Bacterial pneumonia (Streptococcus pneumoniae)

Zachary Rushton

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Inflammatory condition of the lung affecting the alveoli especially Most common infectious agent leading to hospitalization in the world

http://www.nlm.nih.gov/medlineplus/ency/images/ency/fullsize/19680.jpg

http://textbookofbacteriology.net/PHILspbloodGram.jpg http://pathmicro.med.sc.edu/fox/strep-pneu_small1.jpg

http://www.nature.com/nrmicro/journal/v6/n4/images/nrmicr o1871-f2.jpg

http://worldpneumoniaday.org/learn/2011-progress-report/

http://cid.oxfordjournals.org/content/51/9/1042/F1.medium.g if

http://www.microbiologyinpictures.com/bacteria%20photos/str eptococcus%20pneumoniae%20photos/streptococcus%20pneum oniae%20027.jpg

http://www.thailabonline.com/bacteria6streppneumo.htm

http://upload.wikimedia.org/wikipedia/commons/thumb/f/fd/Streptococcus_p neumoniae_meningitis%2C_gross_pathology_33_lores.jpg/402pxStreptococcus_pneumoniae_meningitis%2C_gross_pathology_33_lores.jpg

http://practicalhospital.com/wpcontent/uploads/2011/07/c7_nasopharynx-297x300.jpg

http://www.thailabonline.com/bacteria6streppneumo.htm

White blood cell

pneumolysin

http://funwithgovernment.blogspot.com/2011/03/killer-diseases-inphilippines.html

http://www.nlm.nih.gov/medlineplus/ency/imagepages/19680.htm

http://www.nlm.nih.gov/medlineplus/ency/imagepages/19680.htm

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Penicillin resistance has led to increase in mortality rate ◦ Penicillin- nonsusceptible  19.4% ◦ Susceptible  15.7% ◦ Production of altered penicillin binding proteins

http://sciencenaturalphenomena.blogspot.com/2009/04/cephalosporins.html

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There currently exists a 23 valent capsular polysaccharide vaccine Based on knowledge that antibodies formed against the capsule are very effective in preventing lethal S. pneumoniae infection

1 shot

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5 years later, a booster is given

http://www.sciencephoto.com/media/283366/enlarge

Arancillo. (2010, February). Pneumonia [Video file] Retrieved from http://www.youtube.com/watch?v=Hat0_VDQACA

Hanage W, Fraser C, Tang J, Connor T, Corander J. 2009. Hyper-Recombination, Diversity, and Antibiotic Resistance in Pneumococcus. Science: 324:1454-1457. Huang SS, Platt R, Rifas-Shiman SL, Pelton SI, Goldmann D, Finkelstein JA. 2005. Post-PCV7 Changes in Colonizing Pneumococcal Serotypes in 16 Massachusetts Communities, 2001 and 2004. Pediatrics: 117:593-594. Magner L N. 2009. A history of infectious diseases and the microbial world. Westport, Conn.: Praeger. xxiv, 225 p. Pneumonia Progress Report 2011. [Internet]. 2012. Baltimore, MD: IVAC. [cited 2012 Mar 29] Available from: http://worldpneumoniaday.org/wp-content/uploads/2011/11/IVAC2011_PNEUMONIA_PROGRESS_REPORT.pdf. "Streptococcus Pneumoniae." Thai Labonline. . 2 April 2012. Tomasz A. c2000. Streptococcus pneumoniae : Molecular biology & mechanisms of disease. Larchmont, NY: Mary Ann Liebert Inc. xxi, 501 p. Washer P. 2010. Emerging infectious diseases and society. Houndmills, Basingstoke, Hampshire [England] ;: Palgrave Macmillan. xiv, 191 p.