Curriculum vitae
Dr. Oliver Spadiut Curriculum vitae Dr. Oliver Spadiut
Personal Details Date and place of birth: Nationality: Academic titles: Address:
07.05.1980 in Vienna, Austria Austria Priv. Doz. Dipl.-Ing. Dr.nat.techn. TU Wien, Institut für Verfahrenstechnik, Umwelttechnik und Techn. Biowissenschaften, Gumpendorferstrasse 1A/166-4, 1060 Wien
E-mail:
[email protected]
Website: http://www.vt.tuwien.ac.at/bioprocess_engineering/integrated_bioprocess_development
Education 10/99-07/05 11/04-04/05 07/05 01/06-11/08
06/06 06/07-11/07 11/08 06/10 06/11 04/15
Master study in “Food Science and Biotechnology”, University of Natural Resources and Life Sciences BOKU, Vienna Visiting scholar at the School of Biotechnology, Suranaree University of Technology SUT, Nakhon Ratchasima, Thailand Master of Science in “Food Science and Biotechnology” graduated with distinction Ph.D. Thesis at the Division of Food Biotechnology, University of Natural Resources and Life Sciences BOKU, Vienna (Title: “Pyranose 2-oxidase: playground for enzyme evolution”) Successful completion of the “Practical Course on Directed Enzyme Evolution” at the Institute of Biotechnology, Vilnius, Lithuania Visiting scientist at the Chemistry Department, University of British Columbia UBC, British Columbia, Canada Ph.D. degree (Dr. nat. techn.) in “Food Science and Biotechnology” graduated with distinction Successful completion of the “Basic Unicorn Training Course” at the GE Healthcare Headquarter, Uppsala, Sweden Successful completion of the course “Design of Experiments” at the Umetrics Head Quarter, Malmö, Sweden Habilitation (venia docendi) in Biotechnology, Habilitation Thesis “Horseradish peroxidase – from genome to protein”
Career History 01/09-08/09
09/09-09/10
09/10-present 01/15-present
Post-Doc at the Division of Glycoscience at the Royal Institute of Technology KTH, Stockholm, Sweden Project “Structure-function studies on enzymes involved in biogenesis and degradation of plant cell walls” Post-Doc at the Division of Glycoscience at the Royal Institute of Technology KTH, Stockholm, Sweden Project “Enzymes for the degradation of wood cell polymers” founded by the Wallenberg Wood Science Center (http://wwsc.se) University Assistant at the Research Division of Biochemical Engineering at the University of Technology VUT, Vienna, Austria Group Leader “Integrated Bioprocess Development” at the Research Division of Biochemical Engineering at the University of Technology VUT, Vienna, Austria
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Curriculum vitae
Dr. Oliver Spadiut
Other academic recognition Main awards 03/09 04/09 09/09 05/12 08/12
“Award for Excellent PhD Thesis 2008” conferred by the University Fellowship Organisation Austria (Allgemeine Hochschulstipendienstiftung Österreich) “Research Award 2009 for Young Scientists” conferred by the AGRANA Group Austria (http://www.agrana.com) “Award for excellent PhD Thesis 2009” conferred by the Austrian Association of Molecular Life Sciences and Biotechnology ÖGMBT (http://www.oegmbt.at) “Paper of the Month Award” conferred by the scientific magazine LABORWELT (http://www.laborwelt.de/) “Achievement Award” conferred by Novartis for developing a business concept for a biotechnology company during Novartis International Biotechnology Leadership Camp 2012
Reviewer American Society of Microbiology, Applied and Environmental Microbiology, Applied Microbiology and Biotechnology, Applied Biochemistry and Biotechnology, BBA General Subjects, Biochemical Engineering Journal, Bioresource Technology, Biotechnology Advances, Biotechnology Progress, Biotechnology Reports, Bioengineered, BMC Biotechnology, Chemical Papers, Clinical and Vaccine Immunology, eBooks Bentham, Enzyme and Microbial Technology, European Food Research and Technology, FEMS Yeast Research, Frontiers in Microbiology, International Journal of Food Engineering, Journal of Bacteriology, Journal of Biological Engineering, Journal of Molecular Catalysis B: Enzymatic, Microbial Cell Factories, Physiologia Plantarum, PLOS One, Preparative Biochemistry and Biotechnology, Process Biochemistry, Processes, Scientific Reports, Sensors, Springer Plus
Summary of Technical Experience Biochemical, microbiological and molecular biological standard techniques Protein engineering: epPCR, gene shuffling, saturation mutagenesis, mutator strain, family shuffling, development of screening assays, FACS Rational protein design Protein production in E. coli and P. pastoris, protein purification techniques and biochemical protein characterization Fermentation (planning, set up, data analysis) in batch, fed-batch and continuous mode Bioconversion experiments and HPLC analysis Downstream Processing Crystallization set-up and data collection at the synchrotron Multivariate Data Analysis; Design of Experiments (MODDE)
Main fields of Research Integrated bioprocess development – from gene to protein; Tailoring enzymes and engineering strains for specific applications; Development of PAT tools for online process monitoring and control
Project Track Record (5 main projects) 2010-2013 since 2011
Project Leader of the Industrial Project “Bulk- und Intermediate-Freezing von Proteinen” in cooperation with the Institut für Luft- und Kältetechnik ILK Dresden Junior Faculty Member of the VUT Doctorate Program on “Catalysis Materials and Technology (CatMat)” (http://catmat.tuwien.ac.at)
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Curriculum vitae since 2012
since 2013
since 2013
Dr. Oliver Spadiut
FWF Stand Alone Project “Glycoengineered horseradish peroxidase for targeted cancer treatment” P24861-B19 funded by the Austrian Science Fund FWF (http://fwf.ac.at/asp/projekt_res.asp) Project Leader of Industrial Project „Quantitative Prozessentwicklung, Produktivitäts-Optimierung sowie Charakterisierung der Produktionsplattform“ in cooperation with Sciotec Diagnostic Technologies GmbH Module Leader of the CD Laboratory Module “Development of an all-in-one methodology for downstream processing and concomitant impurity monitoring”
Main international collaboration partners during the past 5 years Dr. Christina Divne, Royal Institute of Technology KTH, Stockholm, Sweden Prof. Gabi Dachs, University of Otago, Christchurch, New Zealand Dr. Lisa Folkes, University of Oxford, Oxford, United Kingdom Dr. Hidde de Jong, INRIA, Grenoble, France Prof. Hans Geiselmann, University Joseph Fourier, Grenoble, France
Teaching and Tutoring Teaching at the Vienna University of Technology: Biochemistry and Biotechnology LU (3.5 h) Bioprocess Technology and Bioanalytics LU (5.0 h) Modelling and Methods in Bioprocess Development VO (2.0 h) Biotechnological Methodology PS (2.0 h) CatMat lectures Teaching at the Fachhochschule Technikum Vienna: Biotechnology ILV / MTE-3 (3.0 h) Tutoring: Supervision of more than 70 Bachelor and Master students including: planning of theses and corresponding experiments, supervising the students in the lab and correction of theses Supervision of 5 PhD students at the Vienna University of Technology: Christian Dietzsch, Simona Capone, Britta Eggenreich, David Wurm, Vignesh Rajamanickam Supervision of 1 PhD student at the FH Technikum Vienna: Babette Maleiner
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