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Thanks Genentech for Welcoming Roche Latin America to San Francisco

Pharma Medicines Leadership Team

Pharma Medicines P. Soriot Global Product Develop.

North America Comm Ops

Global Technical Ops

Western Europe Comm Ops

Global Product Strategy

Asia Pacific Comm Ops

Global Portfolio Mgmt

LatinAmerica Comm Ops

HR.

CEMAI Comm Ops

Finance

Pharma Site Head Basel

H. Barron/ SSF

P. Yang / Basel

D. Loew / Basel

SSF

M. Knierim / SSF

P. Mongrolle / Basel

I. Clark / SSF

P. Hug / Madrid

L. Miels / Shanghai

J. Rupp / Sao Paulo

T. Göker / Basel

M. Baltisberger*

* Not on MLT

Why are we here? Joerg Rupp - Regional Head Latin America To introduce LATAM to Genentech – Careers – Living in the region To help you understand why LATAM offers good career development To profile career opportunities in LATAM To discuss the skills and experiences that make people successful in LATAM To attract amazing US talent to the region To build on our common ambition to improve patients' lives

Latin America to San Francisco

Introduction Video

Latin America Region / Pharma Medicines Head Latin America Pharma Medicines Jörg-Michael Rupp

Finance & SSC Luca Scavo

Argentina & Uruguay Osvaldo de la Fuente

Costa Rica (PRISA) Alvaro Soto

Business Development Marcelo H. Santos

Brazil

Adriano Treve

Mexico

Miguel Munera

Human Resources Carolyn Medley

Chile

Renê Delsin

Peru

Peter Braun

Informatics

Vera Marques

Colombia & Ecuador Rolf E. Hönger

Venezuela

Lars Nielsen

Roche Latin America Overview Roche LA Affiliates & Sales**

Total Sales: CHF 2.8 Bio

Mexico (CHF 534 Mio)

Double-digit sales growth since 2002 Among Top 5 major companies in the total Latin American pharmaceutical market* ~ 4.000 employees; 1.400 Field Force Mexico & Brazil: In the top 10 for Roche and almost 58% of regional sales

Venezuela (CHF 324 Mio) Central America & Caribbean (CHF 138 Mio)

Colombia (CHF 228 Mio)

Ecuador (CHF 48 Mio)

Peru Mio)

(CHF 48

Most Roche companies present in LA for more than 70 years Top selling products 2010: MabThera, Herceptin, Avastin, Tamiflu, Rivotril

Chile (CHF 72 Mio)

Brazil (CHF 1`077 Mio)

Uruguay (CHF 34 Mio)

Argentina Mio)

* Estimates based on IMS Retail Audits + IMS Non-Retail Audits Brazil & Mexico / ** Estimated 2010 sales in CHF at average 2009 exchange rates

(CHF 269

Why Latin America is a good choice for your Career Development?

Entirely different work experience from the US

Enhances your skills of dealing with uncertainty, the unexpected, and shifting priorities Gives you international experiences of dealing across multiple countries & Cultures Stretches your skills in leading a workforce that is incredibly diverse Latin America has developed a leadership pipeline that has enabled people to move to significant leadership roles in other parts of the world

Why Latin America is a good choice for your Career Development?

Gives you the opportunity to work in emerging and growing markets It opens your eyes to entirely new environments - political, social and economic It develops your hands on generalist skills, whilst demanding high level strategic thinking Our regional business team offers demanding career opportunities because they act as the catalyst between HQ and the region. (The face of the region)

David Loew From Mexico to Europe

David Loew Testimonial Video

Regional Team Latin America

Comercial Development Directo LA Marcelo H. Santos

Training Coordinator

Assistant

Márcia Cunha

Regional Strategic Planning Manager Bruno Vasques

Regional Funding Manager Stefan W. Weber

Business Analyst Henrique Leite

Business Analyst Daniel Oliveira

Tatiana Oliveira

Regional Marketing Manager, RA Raul Vivar (MEX)

Marketing Analyst Kory Portela

Regional Clinical Trial Manager, PA Anita Silva

Regional Marketing Manager, Taspoglutide Juliana Pisani

Regional Biosimilars Manager Vanessa Tubel

Regional Marketing Manager, Oncology TBD

Marketing Analyst Maria C. Pinheiro

Regional CRM Manager André Veloso

Why the regional team? Enhances your communication and coordination skills because you will work across every market in the region Offers the unique opportunity to develop an understanding of an entire region. Requires leading and influencing colleagues in the region who do not report directly to you.

Managing major international and regional events including Oncolatina and Rheumalatina High level of exposure to HQ A mini McKinsey talent development experience Track record of significant career moves out of this team to other parts of the Roche world

Cristina Souza From the Regional Team to Switzerland HQ

Cristina Souza Testimonial Video

Brazil Fact Sheet

Brazil affiliate & LATAM regional team collocated in Sao Paulo Manufacturing facility in Rio de Janeiro Over 1’000 people

36% of Roche LATAM sales World’s 10th largest economy Average GDP Growth 2005 – 2008 4.6% Population of 190 mio with 74% of population living above the poverty line Official Language Portuguese

Why Brazil?

Diverse culture Top 10 Roche Market Highly dynamic environment Complex market with huge upside potential Regional dimension Exposure to high level senior management Ample opportunity for learning!! Rio de Janeiro Carnival!!

Duncan Trew From Mexico to Switzerland HQ

Duncan Trew Testimonial Video

Mexico Fact Sheet

21% of Roche LATAM sales Over 1’000 people Manufacturing facility

12th largest world economy Average GDP growth 2005 – 2008 3.25%.

Why Mexico?

Proximity to the USA

Tends to be more aligned to FDA decisions The taste of a different culture A career enhancing, cross-cultural commercial experience A stable and successful top team Top 10 Roche market Interesting projects because of emerging market status A wide range of products, franchises and business units Amazing beaches and Tequila!!

Dimitrios Papadopoulos From Switzerland HQ to Argentina

Dimitrios Papadopoulos Testimonial Video

Argentina Fact Sheet

10% of Roche LATAM sales Over 400 employees Avergae GDP growth 2005 - 2008 8.3%. Population of 41 mio with 86% of population above poverty line Language: Spanish

Why Argentina?

A blend of cultures – European, Arabic and Asian Quality of Life Index 2010 showed Argentina as the 26th best place to live in the world A challenging social and political environment that stretches your creative skills A very stable management team A mid size player in Latin America with a good share of voice in the region Strong internal investment and budgets especially in oncology The land of tango and great red wine

Max Bucher From Costa Rica and Argentina to Switzerland HQ

Max Bucher Testimonial Video

Central America and The Caribbean Fact Sheet

HQ: Costa Rica 4% of Roche LATAM sales Language: English & Spanish

Central America & The Caribbean A region within a region (23 countries)

Complex geography Different regulatory environments Investment decisions Culturally & Ethnically Diverse. Cross cultural management Different Health Systems Flexibility Amazing Caribbean destinations.

Peter Braun From México to Switzerland HQ and Back to Perú

Experiencie

’10 -

General Manager

’06 –’10

Life Cycle Leader – Herceptin (Tarceva)

’03–’06

Marketing & Sales Director

’00–’03

Business Unit Head – Specialty

’99

MBA

’97-’98

Intl Product Manager – Xenical

’94-’97

Product Manager - Oncology

’92-’93

Business Trainee

’91-’92

Sales Representative

Additional Information

Education • Undergrad – –

BA Arts – U. of Penn (College) BA Sc in Econ – U. of Penn (Wharton)

• Graduate –

Family Danielle (wife) Eric (8) & Nathalie (10)

MBA - INSEAD

Languages • English / Spanish • German • French • Dutch

Mother / Father

Roche-Mexico - Oncology Product Manager

What did I offer?

What did I learn?

• Specific oncology knowledge (in mid-90s Roche was relatively new to field)

• Opportunity to gain broad marketing & sales experience quickly

• Analytical & organizational skills with strategic framework

• Chance to “just do it” – apply analytical and organizational skills with focus on pragmatic solutions to drive business

• Network in Basel Headquarters • Spanish fluency and familiarity with region allowed me to hit ground running

• Importance of people

Keys to success in operating in a foreign country

Open mind to new environment and culture – Genuine interest in country and culture Quiet confidence but listen carefully (you can’t know it all!)

Do not copy paste, previous experience and skills of high value but must be adapted to local situation Energy

So what do we expect from you if you come to LATAM?

High level of integrity, passion and courage

An open mind and the ability to be flexible in this unique environment A commitment to learning the culture and language To bring your knowledge and share it with your colleagues

To be prepared to travel A desire to make a difference in Roche and patients' lives To bring innovative solutions to Latin America business challenges

International Assignments

Long-Term – Assignment duration: 1 – 5 years – Usually part of the career development of high potentials Short-Term – Assignment duration: 3 – 12 months – Skill transfer/project work/trouble shooting Local to Local http://rochenet.roche.com/hr/hr-international_assignments/hr-international_assignment_policies.htm

Q&A

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