the 2014 Annual Meeting Scientific Abstract Listing

Scientific Abstract Listing and Annual Meeting Information

April 26 – May 3, 2O14 Philadelphia, PA

Connecting All of Neurology Early Registration Deadline: April 3, 2O14

The 66th AAN Annual Meeting Experience breakthrough research, exceptional education programs, and boundless networking opportunities at the AAN Annual Meeting in Philadelphia, PA, April 26–May 3, 2014.

2O14 Deadlines-At-A-Glance

Location

¡¡ March 26, 2014: Annual Meeting Hotel Reservation Deadline

¡¡ Pennsylvania Convention Center Philadelphia, PA

¡¡ April 3, 2014: Annual Meeting Early Registration Deadline

Headquarter Hotel ¡¡ Marriott Philadelphia Downtown

Future Annual Meeting Dates and Locations ¡¡ Washington, DC April 18-25, 2015

¡¡ Vancouver, BC, Canada April 16-23, 2016

¡¡ Boston, MA April 22-29, 2017

RED: 14AM Register Online Ad Place in AANnews and Others? 8.25 x 5.4375 4C + Bleed

Search, Find, and Register Online Customize Your Week with Easy Online Registration With online registration, you can: Register Book your hotel Plan your itinerary Search for programs by topic or day New! Choose the “Buy All” option to purchase all education courses at one flat rate!

AAN.com/view/AM14

Table of Contents Introduction

Thursday, May 1

Connecting All of Neurology . . . . . . . . . . . 2

Make the Meeting Your Own . . . . . . . . . . . . . . 3 About Program Listings . . . . . . . . . . . . . . . . 4 What’s Included with Your Registration? . . . . . 6 Look What’s New for 2014 . . . . . . . . . . . . 8 See What’s Back by Popular Demand . . . . . . . . . . 9

Meeting Schedule Overviews Meeting-at-a-Glance . . . . . . . . . . . . . . 10 Scientific Sessions-at-a-Glance . . . . . . . . . 14

2014 Award Recipients . . . . . . . . . . 2014 Research Fellowships . . . . . . . . Annual Meeting Program Schedule . Annual Meeting Programs by Topic .

. . . .

. . . .

. . . .

. . . .

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18 . 22 . 24 . 34

Sunday, April 27

Poster Session VI . . . . . . . . . . . . . . . . . . 104 Frontiers in Neuroscience Plenary Session �����������112 Scientific Sessions . . . . . . . . . . . . . . . . . 114 Integrated Neuroscience Sessions . . . . . . . . . . . 116 Poster Session VII . . . . . . . . . . . . . . . . . 118 Scientific Sessions . . . . . . . . . . . . . . . . . 126 Controversies in Neurology Plenary Session �������128

Friday, May 2 Integrated Neuroscience Session . . . . . . . . . . . 130 Clinical Trials Plenary Session��������������������������������������131 Section Topic Controversies/ Integrated Neuroscience . . . . . . . . . . . . . . . 132 Neurology Year in Review Plenary Session . . . 133

Other Interests

Integrated Neuroscience Sessions/ Section Topic Controversies . . . . . . . . . . . . . . 42 Poster Session Floor Plan . . . . . . . . . . . . 47 Poster Session I . . . . . . . . . . . . . . . . . . 48

Tuesday, April 29 Poster Session II . . . . . . . . . . . . . . . . . . 56 Presidential Plenary Session ������������������������������������������ 64 Section Topic Controversies . . . . . . . . . . . . . . 65 Scientific Sessions . . . . . . . . . . . . . . . . . 66 Integrated Neuroscience Sessions . . . . . . . . . . . 68 Poster Session III . . . . . . . . . . . . . . . . . . 70 Scientific Sessions . . . . . . . . . . . . . . . . . 78 Hot Topics Plenary Session ��������������������������������������������� 80

2O14 Annual Meeting On Demand . . . . . . . 134 Connect at Social Events . . . . . . . . . . . . 136 Highlights for Students, Residents, and Fellows . 138

Registration and Meeting Information General Information . . . . . . . . . . . . . . 140 Registration . . . . . . . . . . . . . . . . . . . 144 Hotel Reservations . . . . . . . . . . . . . . . 146 Hotel Map and Amenities . . . . . . . . . . . 148

Travel Information . . . . . . . . . . . . . . . . . 150 Exhibitor Listing . . . . . . . . . . . . . . . . . . 152 66th Annual Meeting Committee Members . . . . . . . 155 Meeting Information and Contacts . . . . . . . . . . . 158

Wednesday, April 30 Poster Session IV . . . . . . . . . . . . . . . . . . 81 Contemporary Clinical Issues Plenary Session����� 89 Scientific Sessions . . . . . . . . . . . . . . . . . 90 Integrated Neuroscience Sessions . . . . . . . . . . . 92 Poster Session V . . . . . . . . . . . . . . . . . . 94 Platform Blitzes . . . . . . . . . . . . . . . . . . 102



Fast, Easy Registration Online  ·  AAN.com/view/AM14 1

Connecting All of Neurology “Welcome to the 66th AAN Annual Meeting! As the world’s largest gathering of neurologists, the AAN Annual Meeting has a long history of connecting all of neurology by bringing together the latest research on the most critical topics facing neurologists. In fact, the meeting not only attracts scientists from around the globe, but it also garners coverage from world-leading media outlets such as the New York Times, Wall Street Journal, USA Today, CNN, NPR, and more. The Annual Meeting is also the go-to place for unparalleled education programming, connecting neurology professionals to nearly 180 courses on 18 topics of interest. With top-tier programming going on every day, all week long, the Annual Meeting is designed to offer customized convenience, no matter what your schedule. So whether you come for a few days—or stay for all eight, you’re bound to have a great experience and leave feeling an even deeper connection to the world of neurology. I look forward to seeing you in historic Philadelphia.” Stefan M. Pulst, MD, FAAN Chair, Meeting Management Committee

Key Dates and Deadlines: Hotel Reservation Deadline:

Location

March 26, 2014 Early Registration Deadline:

Pennsylvania Convention Center Philadelphia, PA

April 3, 2014

Headquarter Hotel

66th AAN Annual Meeting:

Marriott Philadelphia Downtown

April 26 –May 3, 2014

Visit AAN.com/view/AM14

Make the Meeting Your Own On Your Schedule The AAN Annual Meeting is designed to be completely customizable so you can make the experience all your own—and on the schedule that works best for you and/or your practice. Consider how your practice might get the most out of this year’s meeting: send half your staff for the first few days, then the other for the remainder of the meeting. With so many exceptional education programs and scientific sessions available in a variety of subspecialties, plus unparalleled networking opportunities—all week long—the AAN Annual Meeting can be tailored to be a perfect fit for you no matter what your interest, career stage, or schedule. ¡¡ For Students and Junior Members The Annual Meeting is essential, providing exposure to a variety of interests, career disciplines, and opportunities to network. ¡¡ For Neurologists The Annual Meeting is the place for top CME programming, breakthrough scientific research, and opportunities to collaborate with neurology’s thought leaders from around the world.



¡¡ For Other Physicians and Advanced Practice Providers The Annual Meeting is ideal for comprehensive updates on the latest advances in the science and treatment of patients with common neurologic conditions such as dementia, stroke, migraine, MS, and more.

Fast, Easy Registration Online  ·  AAN.com/view/AM14

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About Program Listings The program listing has changed for the better Please refer to the key for the following program definitions:

C Course (paid education program) CQ Colloquium (education program included with meeting registration)





H I P S

Highlights in the Field (section-provided overview in their subspecialty or topic of interest)

Subspecialty in Focus Track The Subspecialty in Focus Track is a series of six special, intensive topic-specific tracks designed for subspecialists, combining an education course with an Integrated Neuroscience Session. The tracks are divided into a morning and an afternoon portion in a single day. Refer to the Meeting Events Schedule for specific times. Look for the Subspecialty in Focus icons ( ) to identify the tracks of your choice.

Integrated Neuroscience Session (scientific session combining invited speakers, data blitz, and poster discussion; included with meeting registration) Poster Session (a hall of posters on a variety of topics. Posters are displayed for 3½ hours, authors will be present for 90 minutes) Scientific Platform Session (didactic session featuring abstracts)

New Program Feature Icons

These new icons will alert you to features of the program experience: The program is part of a Subspecialty in Focus track The program is included with your registration A registration fee is required The program is one of the AAN Leadership Development sessions

Cerebrovascular Disease Sunday, April 27   C33

Prevention of Cardioembolic Stroke in Patients with Nonvalvular Atrial Fibrillation: Recommendations Based on Evidence-based Guidelines and Recent Randomized Trials . . 24

  I2

New Antithrombotic Agents for Stroke Prevention . . . . . . . . . . . . . . . 43

Epilepsy Sunday, April 27   C51

Algorithms in the Diagnosis and Treatment of Epilepsy . . . . . . . . . . . . . 25

  I1

Temporal Lobe Epilepsy and Febrile Seizures . . . . . . . . . . . . . . . . 42

Child Neurology Monday, April 28   C68

Stroke in Childhood and Adolescence . . . . 25

  I4

Recent Advances in Translational Research in Autism . . . . . . . . . . . . . . 45

Sleep Disorders Monday, April 28   C84

Sleep Principles Applied to Neurological Disease . . . . . . . . . . . . . 26

  I3

Clocks, Sleep, Brain Health and Disorders: Impact on Mechanism, Expression, and Treatment . . . . . . . . . . . . . . . . . . . 44

Sports Neurology/Government Services Friday, May 2   C142 Concussion in the Military and in Sports . . . 31   I12

Concussion in Sports and the Military . . . 132

Geriatric Neurology Friday, May 2   C153 Imaging and Genomics for Detecting

Neurodegenerative Proteinopathy in Clinical Practice . . . . . . . . . . . . . . . . 31

  I11

4

2O14 Scientific Abstract Listing and Annual Meeting Information

Proteinopathy in Neurodegenerative Disease . . . . . . . . 130

April 26–May 3, 2O14 Philadelphia, PA

One Flat Rate

and the Entire Education Program is Yours NEW! Registration Buy All option includes access to all the exceptional 2014 Annual Meeting education courses*—in a wide variety of topics—for one flat rate. A great value in CME programming. Select the Buy All Registration Package when you register.

Register today at AAN.com/view/AM14.

* Skills Workshops and Skills Pavilions excluded from Buy All pricing. Attendee must identify courses to be included as part of “Buy All” purchase. Courses are subject to closure due to reaching maximum capacity. Buy All registration option is only available prior to early registration deadline of April 3, 2014.



What’s Included with Your Registration? When planning your week, be sure and take advantage of these FREE education, scientific, practice, advocacy programs, and social events—going on all week long and at no additional cost to you!

FREE Programs to help you: „„ Stay current with the latest research and scientific sessions „„ Enhance your practice with educational colloquia „„ Network with colleagues „„ Participate in Academy business Saturday, April 26

CQ1  BRAINS Colloquium: Understanding and Improving Your Bottom Line 2:00 p.m.–5:00 p.m. Sunday, April 27

  I1  Temporal Lobe Epilepsy and Febrile Seizures 8:00 a.m.–12:00 p.m. CQ2  Research and Technology Colloquium: From Discovery to Therapy 8:00 a.m.–12:00 p.m. CQ3  Patient Safety Colloquium 9:00 a.m.–12:00 p.m. S1  Section Topic Controversies: ICU EEG Monitoring—Seizures in Critically Ill Patients 1:00 p.m.–2:30 p.m. CQ4  Clinical Research Colloquium 1:00 p.m.–5:00 p.m.   I2  New Antithrombotic Agents for Stroke Prevention 1:00 p.m.–5:00 p.m. CQ5  Practice Colloquium: How to Navigate and Succeed in New Payment Models 2:00 p.m.–5:00 p.m. Opening Party 6:00 p.m.–10:00 p.m. Monday, April 28

C61  Residents and Fellows Career Breakfast: The Early Years (registration required) 6:30 a.m.–8:30 a.m. A AN/AANI Business Meeting 8:00 a.m.–8:30 a.m.   I3  Clocks, Sleep, Brain Health and Disorders: Impact on Mechanism, Expression, and Treatment 8:00 a.m.–12:00 p.m. 6

CQ6  Education Colloquium 8:30 a.m.–12:00 p.m. Government Relations Committee Meet and Greet 12:00 p.m.–1:30 p.m. S2  Cancelled

Exhibit Hall Opening Reception 4:30 p.m.–6:30 p.m. Student Interest Group in Neurology (SIGN) Meeting 4:30 p.m.–6:30 p.m. Consortium of Neurology Residents and Fellows Meeting 5:00 p.m.–6:30 p.m. Residents and Fellows Career Forum and Reception 6:30 p.m.–9:00 p.m. Tuesday, April 29

  I4  Recent Advances in Translational Research in Autism 1:00 p.m.–5:00 p.m. AAN/ABPN MOC Informational Session 1:30 p.m.–3:00 p.m. CQ7  Education Research Colloquium 2:00 p.m.–4:30 p.m. CQ8  Health Information Technology Colloquium: Advancements in Technology 2:00 p.m.–5:00 p.m. P1  Poster Session I 3:00 p.m.–6:30 p.m.

2O14 Scientific Abstract Listing and Annual Meeting Information

P2  Poster Session II 7:30 a.m.–11:00 a.m. Presidential Plenary Session 9:00 a.m.–12:00 p.m. Exhibit Hall 11:30 a.m.–5:00 p.m. S3  Section Topic Controversies: PFO: Aggressive Treatment or Just Aspirin 1:00 p.m.–2:30 p.m. S4–S13  Scientific Platform Sessions 1:00 p.m.–2:45 p.m. I5  Revolution of Genetic Tools and the Impact on Neurology 1:00 p.m.–5:00 p.m. I6  Peripheral Neuropathies 1:00 p.m.–5:00 p.m. P3  Poster Session III 3:00 p.m.–6:30 p.m. S14–S23  Scientific Platform Sessions 3:15 p.m.–5:00 p.m. Hot Topics Plenary Session 5:30 p.m.–6:30 p.m.

  Subspecialty in Focus Track   Included with registration   Registration fee required

Wednesday, April 30

Thursday, May 1

P4  Poster Session IV 7:30 a.m.–11:00 a.m. Contemporary Clinical Issues Plenary Session 9:00 a.m.–12:00 p.m. Exhibit Hall 11:30 a.m.–5:00 p.m. S24–S33  Scientific Platform Sessions 2:00 p.m.–3:45 p.m. I7  Emerging Therapeutic Advances in Multiple Sclerosis 2:00 p.m.–6:00 p.m. I8  Clinical Decision Making After the Dust Settles on Clinical Trials 2:00 p.m.–6:00 p.m. P5  Poster Session V 3:00 p.m.–6:30 p.m. S34–S43  Platform Blitzes 4:00 p.m.–5:45 p.m. Current Practice Issues in Neurology 5:30 p.m.–7:00 p.m. Highlights in the Field Sessions 6:00 p.m.–7:00 p.m. Emerging Science Session 6:00 p.m.–7:30 p.m.

P6  Poster Session VI 7:30 a.m.–11:00 a.m. Frontiers in Neuroscience Plenary Session 9:00 a.m.–12:00 p.m. Exhibit Hall 11:30 a.m.–3:00 p.m. S44–S53  Scientific Platform Sessions 1:00 p.m.–2:45 p.m. I9  Emerging Concepts in Headache Therapy 1:00 p.m.–5:00 p.m. I10  The Global Burden of Neurological Diseases 1:00 p.m.–5:00 p.m. P7  Poster Session VII 3:00 p.m.–6:30 p.m. S54–S63  Scientific Platform Sessions 3:15 p.m.–5:00 p.m. Highlights in the Field Sessions 5:30 p.m.–6:30 p.m. Controversies in Neurology Plenary Session 5:30 p.m.–7:00 p.m.

Friday, May 2

  I11  Proteinopathy in Neurodegenerative Disease 8:00 a.m.–12:00 p.m. Clinical Trials Plenary Session 12:00 p.m.–1:30 p.m. S64  Section Topic Controversies: Pain: Methods of Treatment 1:00 p.m.–2:30 p.m.   I12  Concussion in Sports and the Military 1:00 p.m.–5:00 p.m. Neurology Year in Review Plenary Session 5:30 p.m.–7:00 p.m. Closing Party 7:30 p.m.–9:00 p.m.

Extend Your Experience with These Annual Meeting Resources „„ Academy Central: Your one-stop shop for AAN products, services, and more „„ American Brain Foundation: Support cures for brain disease and see the future of neurology „„ Neurology Career Center in Academy Central and the Exhibit Hall: Meet employers, search for jobs, and get career tools „„ Resident/Medical Student Rush Line: Free education program tickets, first-come, first-served „„ Annual Meeting Mobile App: Lite version available now. Full version available March 2014. „„ Annual Meeting On Demand: The digital library of content from the 2014 AAN Annual Meeting educational programs „„ Residents’ Experience: A unique place to network, find information, and participate in informal presentations specifically geared to those in the early stages of their career „„ International Experience: New! Provides an opportunity for international attendees to network and participate in discussions on a variety of topics

Fast, Easy Registration Online  ·  AAN.com/view/AM14

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Look What’s New for 2014 Buy All Registration Option

Meet to Eat

Take advantage of this new option to purchase all your favorite education courses for one flat rate! Hurry—the BUY ALL* option is only available until the April 3 early registration deadline. See page 144 for more information, including Buy All exclusions and price.

You’ll notice something new in the poster sessions this year: A selection of posters will be presented on large monitors, to allow authors to best highlight visually compelling elements such as images and videos.

Looking for another way to network with other neurology professionals? Try a Meet to Eat event Monday, April 28–Thursday, May 1. Meet to Eat events facilitate a gathering of attendees in a casual dinner setting. Choose one of the four nights and the AAN will make a 7:00 p.m. dinner reservation for you and other AAN Annual Meeting attendees who signed up for the same night at one of Philadelphia’s highly recommended restaurants. Meet new people, make new connections, and enjoy a great meal! This service is free of charge; attendees are responsible for the cost of the meal. Please contact Kristine Mitchell at (612) 928-6062 or [email protected] for more information.

Clinical Research Track

Platform Blitzes

For attendees interested in a research career, the AAN has organized a track of programs with that emphasis.

Utilizing a similar format to the popular Emerging Science Session, these dynamic sessions will feature five-minute author presentations followed by five-minutes of questions and answers. The session will conclude with all authors participating in a panel discussion.

New Digital ePosters

More Opportunities to Network ¡¡ The hour between 12:00 p.m. and 1:00 p.m. will be free from courses and sessions each day, making it easy for you to find time to meet with colleagues ¡¡ Connect with colleagues before, during, and after the meeting with the Annual Meeting LinkedIn Group at AAN.com/view/AMLinkedIn . ¡¡ The International Experience provides a place for international attendees to gather, network, and participate in discussions on a variety of topics. The International Experience is open Saturday, April 26 through Friday, May 2.

* Skills Workshops and Skills Pavilions excluded from BUY ALL pricing. Attendee must identify courses to be included as part of “BUY ALL” purchase. Courses are subject to closure due to reaching maximum capacity. BUY ALL registration option is only available prior to early registration deadline of April 3, 2014. 8

2O14 Scientific Abstract Listing and Annual Meeting Information

See What’s Back by Popular Demand These always-popular scientific programs are included free with your registration!

Section Topic Controversies

Integrated Neuroscience Sessions (INS)

AAN Sections will debate controversies related to a specific Sectionrelated topic. This format will feature two speakers arguing a side of the topic, followed by a rebuttal and question and answer period.

These well-attended sessions offer an in-depth look at subspecialty areas using a variety of presentations, including data blitz sessions, poster rounds, and invited speaker sessions.

AAN Plenary Sessions

Get essential updates covering the past year in your subspecialty or topic of interest. Sections will provide overviews in their areas, featuring scientific and educational abstracts, journal articles, subspecialty society updates, tips, resources, and more.

AAN Plenary Sessions are the signature scientific sessions of the Annual Meeting covering critical issues, hot topics, highlights, and significant advances in neurology from the last year. This year’s sessions showcase an outstanding lineup of premier lecturers, chosen by their peers. Join us as they address the latest controversies, breakthroughs, and advances in neuroscience. Sessions run Tuesday, April 29 through Friday, May 2.

Scientific Poster and Platform Sessions

Poster Session QR Codes

Browse more than 2,500 poster and platform presentations covering the latest research on a wide range of interest areas in neurology. Sessions run Monday, April 28 through Thursday, May 1.

The QR code is one of the most popular types of two-dimensional barcodes. The QR tag can be scanned by smart phones or tablets and will link the attendee to the selected poster via AAN’s mobile access. Once the QR tag is scanned, the attendee’s mobile device will link to the poster title, authors, and links to the abstract, poster PDF, and audio file. An attendee can scan a multitude of posters to see the corresponding content.

Highlights in the Field

**Please note that each poster presenter needs to provide permission for his or her poster information to be accessible in the online poster viewing site.



Fast, Easy Registration Online  ·  AAN.com/view/AM14

9

Meeting Schedule Overviews Meeting-at-a-Glance Saturday April 26

Sunday April 27

6:00 a.m. C20–C26 6:30 a.m.–8:00 a.m.

7:00 a.m. 8:00 a.m.

C27–C35

C1–C4

CQ2

8:00 a.m.–12:00 p.m.

8:00 a.m.–12:00 p.m. 8:00 a.m.–12:00 p.m.

Integrated Neuroscience

8:00 a.m.–12:00 p.m.

9:00 a.m.

C5–C7

C36

9:00 a.m.–5:00 p.m.

9:00 a.m.–12:00 p.m. 9:00 a.m.–12:00 p.m. 9:00 a.m.–5:00 p.m.

CQ3

10:00 a.m.

C37–C41

C42–C44 10:00 a.m.–12:00 p.m.

11:00 a.m. 12:00 p.m. OPEN HOUR 12:00 p.m.–1:00 p.m.

1:00 p.m.

C8–C11 1:00 p.m.–5:00 p.m.

S1 CQ4 C45–C53 Integrated Section Topic 1:00 p.m.–5:00 p.m. 1:00 p.m.–5:00 p.m. Neuroscience 1:00 p.m.–5:00 p.m. Controversies 1:00 p.m.–2:30 p.m.

2:00 p.m. 3:00 p.m.

OPEN HOUR 12:00 p.m.–1:00 p.m.

CQ1

CQ5

2:00 p.m.–5:00 p.m.

2:00 p.m.–5:00 p.m.

C12–C19 3:00 p.m.–5:00 p.m.

4:00 p.m. 5:00 p.m. 6:00 p.m.

Opening Party 6:00 p.m.–10:00 p.m.

7:00 p.m. 8:00 p.m.



Current as of 2/10/2014 –Programs and dates are subject to change

Monday April 28

Tuesday April 29

C54–C60

C61

C89–C94

6:30 a.m.–8:00 a.m.

6:30 a.m.–8:30 a.m. (Free, Registration Required)

6:30 a.m.–8:00 a.m.

State Society Leadership Roundtable

6:30 a.m.–8:30 a.m.

7:00 a.m.–8:30 a.m.

AAN/AANI Business Mtg C62–68 8:00 a.m.–8:30 a.m.

8:00 a.m.–12:00 p.m.

CQ6

Run/Walk for Brain Research

Integrated Neuroscience

P2 Poster Session II

7:30 a.m.–11:00 a.m.

8:00 a.m.–12:00 p.m.

8:30 a.m.–12:00 p.m.

C69–70

C71–C76

9:00 a.m.–12:00 p.m. 9:00 a.m.–5:00 p.m.

Presidential Plenary Session

C77

9:00 a.m.–12:00 p.m.

9:30 a.m.–12:00 p.m.

C78–C79 10:00 a.m.–12:00 p.m.

Exhibit Hall

11:30 a.m.–5:00 p.m.

OPEN HOUR 12:00 p.m.–1:00 p.m.

S2 Cancelled

C80–C85

CQ7

CQ8

C86–C87

2:00 p.m.–4:30 p.m.

2:00 p.m.–5:00 p.m.

2:00 p.m.–5:00 p.m.

1:00 p.m.–5:00 p.m.

Integrated Neuroscience 1:00 p.m.–5:00 p.m.

Government Relations Committee Meet & Greet

12:00 p.m.–1:30 p.m.

AAN/ABPN MOC Informational Session

OPEN HOUR 12:00 p.m.–1:00 p.m.

S3 S4–S13 C95–C99 Integrated Section Topic 1:00 p.m.–2:45 p.m. 1:00 p.m.–5:00 p.m. Neuroscience 1:00 p.m.–5:00 p.m. Controversies 1:00 p.m.–2:30 p.m.

C100 2:00 p.m.–5:00 p.m.

1:30 p.m.–3:00 p.m.

P1 Poster Session I

3:00 p.m.–6:30 p.m.

P3 Poster Session III

S14–S23 3:15 p.m.–5:00 p.m.

3:00 p.m.–6:30 p.m.

Exhibit Hall Opening Reception

4:30 p.m.–6:30 p.m.

Hot Topics Plenary Session 5:30 p.m.–6:30 p.m.

Residents and Fellows Career Forum and Reception 6:30 p.m.–9:00 p.m.

Corporate Therapeutic Updates 7:00 p.m.–10:00 p.m.

Paid Programs/Events Programs/Events Included with Registration Additional Events

Meeting-at-a-Glance Wednesday April 30

Thursday May 1

C101–C107

C114–C119

6:30 a.m.–8:00 a.m.

6:30 a.m.–8:00 a.m.

6:00 a.m. 7:00 a.m. 8:00 a.m.

P4 Poster Session IV

P6 Poster Session VI

7:30 a.m.–11:00 a.m.

9:00 a.m.

7:30 a.m.–11:00 a.m.

Contemporary Clinical Issues Plenary Session

Frontiers in Neuroscience Plenary Session

9:00 a.m.–12:00 p.m.

9:00 a.m.–12:00 p.m.

10:00 a.m. 11:00 a.m. Exhibit Hall

12:00 p.m. 1:00 p.m.

Exhibit Hall

11:30 a.m.–5:00 p.m.

AAN/American Brain Foundation Awards Luncheon

11:30 a.m.–3:00 p.m.

OPEN HOUR

OPEN HOUR 12:00 p.m.–1:00 p.m.

12:00 p.m.–1:30 p.m.

S44–S53

C120–C123 Integrated 1:00 p.m.–5:00 p.m. Neuroscience

1:00 p.m.–2:45 p.m.

1:00 p.m.–5:00 p.m.

2:00 p.m.

S24–S33

C108–113

2:00 p.m.–3:45 p.m.

2:00 p.m.–6:00 p.m.

C124–125

Integrated Neuroscience

2:00 p.m.–5:00 p.m.

2:00 p.m.–6:00 p.m.

3:00 p.m.

P5 Poster Session V

3:00 p.m.–6:30 p.m.

4:00 p.m.

Current Practice Issues in Neurology

Highlights in the Field Sessions

6:00 p.m.–7:00 p.m.

Corporate Therapeutic Updates 7:00 p.m.–10:00 p.m.

8:00 p.m.

3:15 p.m.–5:00 p.m.

3:00 p.m.–6:30 p.m.

4:00 p.m.–5:45 p.m.

5:30 p.m.–7:00 p.m.

7:00 p.m.

S54–S63

S34–S43 Platform Blitzes

5:00 p.m. 6:00 p.m.

P7 Poster Session VII

Emerging Science Session

6:00 p.m.–7:30 p.m.

Highlights in the Field Sessions

5:30 p.m.–6:30 p.m.

Controversies in Neurology Plenary C126–131 Session 6:00 p.m.–9:00 p.m. 5:30 p.m.–7:00 p.m.



Current as of 2/10/2014 –Programs and dates are subject to change

Friday May 2

Saturday May 3

C132–C137

C154–C158 C159

6:30 a.m.–8:00 a.m.

6:30 a.m.–8:00 a.m.

C138–C142 Integrated 8:00 a.m.–12:00 p.m. Neuroscience

C160–C165

6:30 a.m.–8:30 a.m.

8:00 a.m.–12:00 p.m.

8:00 a.m.–12:00 p.m.

C143–C148

C166

9:00 a.m.–5:00 p.m.

9:00 a.m.–12:00 p.m.

C167–169 10:00 a.m.–12:00 p.m.

Clinical Trials Plenary Session 12:00 p.m.–1:30 p.m.

OPEN HOUR 12:00 p.m.–1:00 p.m.

S64 C149–C153 Integrated 1:00 p.m.–5:00 p.m. Neuroscience Section Topic 1:00 p.m.–5:00 p.m. Controversies 1:00 p.m.–2:30 p.m.

Neurology Year in Review Plenary Session 5:30 p.m.–7:00 p.m.

Paid Programs/Events

Closing Party 7:30 p.m.–9:00 p.m.

Programs/Events Included with Registration Additional Events



Scientific Sessions-at-a-Glance Sunday, April 27, 2014

S8

 8:00 a.m.–12:00 p.m. I1 

Temporal Lobe Epilepsy and Febrile Seizures . . . . . . . . . . . . 42

 1:00 p.m.–2:30 p.m. S1 Section Topic Controversies:

ICU EEG Monitoring: Seizures in Critically Ill Patients . . . . . . . . . . 42

S9 Sleep

¡¡ Presentation of the Sleep Science Award ¡¡ Presentation of the Wayne A. Hening Sleep Medicine Investigator Award

 1:00 p.m.–5:00 p.m. I2 

New Antithrombotic Agents for Stroke Prevention . . . . . . . . . 43

S10

Monday, April 28, 2014  8:00 a.m.–12:00 p.m. I3 

Clocks, Sleep, Brain Health and Disorders: Impact on Mechanism, Expression, and Treatment . . . . . . . . . . . . . . . . 44

   1:00 p.m.–2:30 p.m. S2 Cancelled

 1:00 p.m.–5:00 p.m. I4 

Recent Advances in Translational Research in Autism . 45

 3:00 p.m.–6:30 p.m. P1 Poster Session I . . . . . . . . 48–55

Tuesday, April 29, 2014  7:30 a.m.–11:00 a.m. P2 Poster Session II . . . . . . . . 56-63 9:00 a.m.–12:00 p.m.   Presidential Plenary Session . . . . . . . . . . . . . 64 Features the AAN’s premier lecture awards for clinically relevant research and a presentation by a leading lecturer. Top researchers speak on some of the most significant findings in neurology in 2014.

 1:00 p.m.–2:30 p.m. S3 Section Topic Controversies:

PFO: Aggressive Treatment or Just Aspirin . . . . . . . . . . . . . 65

 1:00 p.m.–2:45 p.m. Scientific Platform Sessions . . . 66–67 S4 MS and CNS Inflammatory Disease: Clinical Trials S5 Cerebrovascular Disease and Interventional Neurology: Pre-hospital, Telemedicine, and Related Topics S6 Neuromuscular Disease: Gene Therapy S7 Parkinson’s Disease: Preclinical and Clinical Therapeutics

Aging, Dementia, and Cognitive and Behavioral Neurology: PET Imaging ¡¡ Presentation of the Potamkin Prize for Research in Pick’s, Alzheimer’s Disease, and Related Diseases

HIV, PML, and Cerebral Malaria ¡¡ Presentation of the Bruce S. Schoenberg International Award in Neuroepidemiology

S11

Neuro Trauma, Critical Care, and Sports Neurology Cerebrovascular Disease and Interventional Neurology: Epidemiology and Risk Factors S13 MS and CNS Inflammatory Disease: MRI Atrophy Measures and Correlations  1:00 p.m.–5:00 p.m. I5 Revolution of Genetic Tools and the Impact on Neurology . . . 68  1:00 p.m.–5:00 p.m. I6 Peripheral Neuropathies . . . . . 69  3:00 p.m.–6:30 p.m. P3 Poster Session III . . . . . . . . 70–77  3:15 p.m.–5:00 p.m. Scientific Platform Sessions . . . 78–79 S14 MS and CNS Inflammatory Disease: Animal and In Vitro Studies S15 Cerebrovascular Disease and Interventional Neurology: Clinical and Imaging Biomarkers and Genetics S16 Neuromuscular and Clinical Neurophysiology (EMG): Clinical Trials and Therapy S17 Parkinson’s Disease: Genetics and Epidemiology S18 Aging, Dementia, and Cognitive and Behavioral Neurology: Behavioral Neuroscience S19 Neuro-ophthalmology/Neuro-otology I S20 Pain and Palliative Care ¡¡ Presentation of the Mitchell B. Max Award for Neuropathic Pain S12

S21

Neurorehabilitation and Neural Repair

iPosters, a virtual poster hall, that transforms your poster hall into an online and mobile experience—both during a meeting and long after. ¡¡ Online, interactive, fully searchable poster database with the ability to magnify the poster content for detailed viewing, contact the author directly with comments or questions, bookmark posters for easy access on return visits, and much more.

14

¡¡ New this year: Poster authors have the ability to record a 5- to 7-minute summary of their poster. This summary will be linked to the author’s iPoster submission and will give viewers the ability to hear about the poster from the author, in addition to viewing at it.

2O14 Scientific Abstract Listing and Annual Meeting Information

S22 Neuro-oncology S23

MS and CNS Inflammatory Disease: Novel Therapeutics ¡¡ Presentation of the John Dystel Prize for Multiple Sclerosis Research

5:30 p.m.–6:30 p.m.   Hot Topics Plenary Session . . . . . . . . . . . . . . 80 Features translational research related to clinical issues of

importance. Four outstanding physician-scientists provide summaries of their recent research findings and describe the clinical implications of the results.

Wednesday, April 30, 2014  7:30 a.m.–11:00 a.m. P4 Poster Session IV . . . . . . . . 81–88 9:00 a.m.–12:00 p.m.   Contemporary Clinical Issues Plenary Session . . . . . . . . . . . . . . . . . . . . . . 89 Highlights issues most critical to practicing neurologists,

including abstracts related to new therapeutic developments, clinical applications of basic and translational research, and innovative technical developments. Commentary and discussion follow each presentation.

 2:00 p.m.–3:45 p.m. Scientific Platform Sessions . . . 90–91 S24 Diet and Hormonal Influences in MS S25 Cerebrovascular Disease and Interventional Neurology: Hemorrhage, Aneurysms, and Vascular Malformations S26 Biomarkers in Neuromuscular Diseases S27 Dystonia, Tremor, and Other Movement Disorders ¡¡ Presentation of the Movement Disorders Research Award S28 Aging, Dementia, and Cognitive and Behavioral Neurology: Dementia Genetics ¡¡ Presentation of the Norman Geschwind Prize in Behavioral Neurology S29 Epilepsy and Clinical Neurophysiology: Inflammation, Status Epilepticus, and Genetics ¡¡ Presentation of the Dreifuss-Penry Epilepsy Award S30 Education, Research, and History ¡¡ Presentation of the Lawrence C. McHenry Award: An Award for the History of Neurology ¡¡ Presentation of the S. Weir Mitchell Award S31 General Neurology I S32 Headache: Basic Science and Imaging ¡¡ Presentation of the Harold Wolff-John Graham Award: An Award for Headache/Facial Pain Research S33 Cognition Fatigue in MS  2:00 p.m.–6:00 p.m. I7 Emerging Therapeutic Advances in Multiple Sclerosis . . . . . . . . . . 92



 2:00 p.m.–6:00 p.m. I8 Clinical Decision Making After the Dust Settles on Clinical Trials . . 93  3:00 p.m.–6:30 p.m. P5 Poster Session V . . . . . . . .94–101  4:00 p.m.–5:45 p.m. Platform Blitzes . . . . . . . . . 102–103 S34 MS and CNS Inflammatory Disease: Risk Factors for MS Disease and Course S35 Cerebrovascular Disease and Interventional Neurology: Issues in Acute Treatment S36 Neuromuscular Disease: Clinical S37 Clinical Aspects of Parkinson’s Disease S38 Aging, Dementia, and Cognitive and Behavioral Neurology: Plasma and Other Biomarkers S39 Neuro-ophthalmology/Neuro-otology II S40 General Neurology II S41 Headache: Clinical S42 Child Neurology I S43 Epilepsy and Clinical Neurophysiology (EEG): Cognition  6:00 p.m.–7:00 p.m. Highlights in the Field H1 Child Neurology H2 Epilepsy H3 Geriatric H4 Headache & Facial Pain H5 Movement Disorders H6 Multiple Sclerosis H7 Neural Repair & Rehabilitation H8 Neuro-oncology H9 Neuro-ophthalmology/Neuro-otology H10 Sleep H11 Sports Neurology  6:00 p.m.–7:30 p.m. Emerging Science Session

Thursday, May 1, 2014  7:30 a.m.–11:00 a.m. P6: Poster Session VI . . . . . . 104–111 9:00 a.m.–12:00 p.m.   Frontiers in Neuroscience Plenary Session . . 112 Focuses on translational research related to clinical issues of

importance. Six physician scientists outline their recent research findings, along with the clinical implications.

 1:00 p.m.–2:45 p.m. Scientific Platform Sessions . . 114–115 S44 MS and CNS Inflammatory Disease: Neuroimaging I S45 Cerebrovascular Disease and Interventional Neurology: Rehabilitation, Recovery, and Complications S46 Neuromuscular Disease: Genetics, Pathogenesis, and Measures

Fast, Easy Registration Online  ·  AAN.com/view/AM14 15



Scientific Sessions-at-a-Glance S47

Movement Disorders: Huntington’s Disease, Ataxia, and Wilson’s Disease ¡¡ Presentation of the Jon Stolk Award in Movement Disorders for Young Investigators

S48

Aging, Dementia, and Cognitive and Behavioral Neurology: MRI Imaging Practice, Policy, and Ethics Epilepsy and Clinical Neurophysiology (EEG): Electrophysiology, Imaging and Functional Connectivity ¡¡ Presentation of the Founders Award

S49 S50

S51

Cerebrovascular Disease and Interventional Neurology: Large Vessel Atherosclerotic Disease ¡¡ Presentation of the Michael S. Pessin Stroke Leadership Prize

S52

General Neurology III S53 MS and CNS Inflammatory Disease: Biomarkers and Therapeutic Mechanisms  1:00 p.m.–5:00 p.m. I9 Emerging Concepts in Headache Therapy . . . . . . . . . 116  1:00 p.m.–5:00 p.m. I10 The Global Burden of Neurological Diseases . . . . . . . 117  3:00 p.m.–6:30 p.m. P7 Poster Session VII . . . . . . 118–125  3:15 p.m.–5:00 p.m. Scientific Platform Sessions . . 126–127 S54 MS and CNS Inflammatory Disease: Neuroimaging II S55 Pediatric Stroke and Stroke in the Young S56 Anterior Horn Disease ¡¡ Presentation of the Sheila Essey Award: An Award for ALS Research S57 S58 S59 S60 S61 S62 S63

Movement Disorders: Imaging Aging, Dementia, and Cognitive and Behavioral Neurology: Clinical Aspects Epilepsy and Clinical Neurophysiology (EEG): Reproduction, Health Care Delivery, and Co-morbidities Child Neurology II Muscle Disease: Gene Therapy and Models Cerebrovascular Disease and Interventional Neurology: Cognitive and Behavioral Neuromyelitis Optica and Autoimmune Encephalitis

 5:30 p.m.–6:30 p.m. Highlights in the Field H12 Adult Intellectual and Developmental Disabilities H13 Endovascular and Interventional Neurology, and Stroke and Vascular Neurology H14 Women’s Issues in Neurology H15 Critical Care 5:30 p.m.–7:00 p.m.   Controversies in Neurology Plenary Session . . . . . . . . . . . . . . . . . . . . . . 128 The program features experts discussing the most current and controversial issues in neurology. It is set up as a series of debates in which two speakers argue opposing sides of a single topic, followed by a rebuttal. Each round concludes with a 10-minute question and answer period.

Friday, May 2, 2014  8:00 a.m.–12:00 p.m. I11 

Proteinopathy in Neurodegenerative Disease . . . . 130

12:00 p.m.–1:30 p.m.   Clinical Trials Plenary Session . . . . . . . . . . . . 131 This mid-day session covers important clinical topics that affect patient care identified from other society meetings. The latest updates within several clinical trials conducted over the course of the last year will be presented with an open panel discussion at the conclusion.

 1:00 p.m.–2:30 p.m. S64 Section Topic Controversies: Pain: Methods of Treatment . . . . 132 1:00 p.m.–5:00 p.m. I12  Concussion in Sports   and the Military . . . . . . . . . . . . 132 5:30 p.m.–7:00 p.m.   Neurology Year in Review Plenary Session . . 133 This plenary session will feature six speakers, each focusing on the latest research that has happened in the last year within a specific subspecialty topic.

QR Code ¡¡ The QR code is one of the most popular types of twodimensional barcodes. The QR tag can be scanned by smart phones or tablets and will link the attendee to the selected poster via AAN’s Mobile access. Once the QR tag is scanned,

the attendee’s mobile device will link to the poster title, authors, and links to the abstract, poster PDF, and audio file. An attendee can literally scan a multitude of posters to see the corresponding content.

Please note that each poster presenter needs to provide permission for their poster information to be accessible in the online poster viewing site. 16

2O14 Scientific Abstract Listing and Annual Meeting Information



2014 Award Recipients AAN Alliance Awards

John Dystel Prize for Multiple Sclerosis Research

Founders Award

Presented by the American Academy of Neurology and the National Multiple Sclerosis Society and made possible through a special contribution for the John Dystel Multiple Sclerosis Research Fund at the National Multiple Sclerosis Society.

Sponsored by the American Brain Foundation and endowed by the Alliance Founders and S. Weir Mitchell Permanent Endowment. Recipient: Shennan Weiss, MD, PhD / New York, NY S50: Epilepsy and Clinical Neurophysiology (EEG): Electrophysiology, Imaging, and Functional Connectivity Thursday, May 1, 1:00 p.m. Resection of Ictal Phase Locked HFOs is Correlated With Outcome Following Epilepsy Surgery S. Weir Mitchell Award

Sponsored by the American Brain Foundation and endowed by the Alliance Founders and S. Weir Mitchell Permanent Endowment. Recipient: Michael Fox, MD, PhD / Newton, MA S30: Education, Research, and History Wednesday, April 30, 2:30 p.m. Lesion-Based Network Analysis: Identifying Distributed Effects of Peduncular Hallucinosis Lesions A.B. Baker Award for Lifetime Achievement in Neurologic Education

Recipient: Barry Arnason, MD / Chicago, IL S23: MS and CNS Inflammatory Disease: Novel Therapeutics Tuesday, April 29, 3:15 p.m. Sheila Essey Award: An Award for ALS Research

Presented by the American Academy of Neurology and The ALS Association and supported through the philanthropy of the Essey Family Fund and The ALS Association. Recipient: Jeremy Shefner, MD, PhD / Syracuse, NY S56: Anterior Horn Disease Thursday, May 1, 3:15 p.m. American Brain Foundation Chair’s Award

Sponsored by the American Brain Foundation. Recipient: Linda M. Selwa, MD, FAAN / Ann Arbor, MI

Funded by and endowment created by matching funds from the A.B. Baker Family Trust and Novartis Pharmaceuticals.

Norman Geschwind Prize in Behavioral Neurology

Recipient: Jerome Posner, MD, FAAN / New York, NY CQ6: Education Colloquium Monday, April 28, 8:30 a.m.

Sponsored by the American Academy of Neurology and the AAN Behavioral Neurology Section and endowed through the Dr. Geschwind’s family, friends, and colleagues; Pfizer Inc; and the Society for Behavioral and Cognitive Neurology.

AAN Award for Creative Expression of Human Values in Neurology

Recipient: Roy Hamilton, MD, MS / Philadelphia, PA S28: Aging, Dementia, and Cognitive and Behavioral Neurology: Dementia Genetics Wednesday, April 30, 2:00 p.m.

Sponsored by the Neurology Ethics, Law, and Humanities Committee. Recipient: Jorge L. Almodovar-Suarez, MD / Manchester, NH

Mitchell B. Max Award for Neuropathic Pain

Dreifuss-Penry Epilepsy Award

Sponsored by the American Academy of Neurology and endowed by the United States Cancer Pain Relief Committee, the Mayday Fund, and friends of Dr. Mitchell Max.

Sponsored by the American Academy of Neurology and endowed by members of the AAN Epilepsy Section; Abbott Laboratories, Inc.; Cephalon, Inc.; Cyberonics, Inc.; Elan Pharmaceuticals, Inc.; GlaxoSmithKline; Novartis Pharmaceuticals; Ortho-McNeil Neurologics; Pfizer Inc; Shire US, Inc; and UCB Pharma.

Recipient: Kathleen Foley, MD / New York, NY S20: Pain and Palliative Care Tuesday, April 29, 3:15 p.m.

Recipient: Catherine Schevon, MD, PhD / New York, NY S29: Epilepsy and Clinical Neurophysiology: Inflammation, Status Epilepticus, and Genetics Wednesday, April 30, 2:00 p.m.

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2O14 Scientific Abstract Listing and Annual Meeting Information

Jon Stolk Award in Movement Disorders for Young Investigators

Lawrence C. McHenry Award: An Award for the History of Neurology

Sponsored by the American Academy of Neurology and endowed by Kyowa Pharmaceuticals, Inc.; Lineberry Research; Quintiles; and Dr. Dennis Gillings.

Sponsored by the American Academy of Neurology.

Recipient: Alice Chen-Plotkin, MD / Philadelphia, PA S47: Movement Disorders: Huntington’s Disease, Ataxia, and Wilson’s Disease Thursday, May 1, 1:00 p.m. Association of Indian Neurologists in America (AINA) Lifetime Achievement Award

Endowed by the Association of Indian Neurologists in America (AINA). Recipient: Avindra Nath, MBBS, FAAN / Bethesda, MD During the AINA Business Meeting Tuesday, April 29, 2014, at 7:15 p.m. International Scholarship Award

Sponsored by the American Academy of Neurology International Subcommittee. Recipients: Mohammadkazem Bakhshandeh Bali / Tehran, Iran

Recipients: Farrah Mateen, MD, PhD / Boston, MA Christopher Boes, MD / Rochester, MN S30: Education, Research, and History Wednesday, April 30, 2:00 p.m. “Pinheads”: Neurological Disorders at the Greatest Show on Earth Medical Student Essay Awards

Sponsored by the American Academy of Neurology. Extended Neuroscience Award

Recipient: Ran (Richard) Liu, MSc / Coquitlum, BC, Canada P2: Poster Session II Tuesday, April 29, 7:30 a.m. Voice Discrimination and Recognition in Patients with Prosopagnosic Complaints G. Milton Shy Award in Clinical Neurology

Recipient: David Asuzu, PhD / New Haven, CT P2: Poster Session II Tuesday, April 29, 7:30 a.m. HAT Score Outperforms 7 other Hemorrhagic Transformation Scores



Prasanna Venkatesan Eswaradass / Salem, India



Meng-Shan Tan / Qingdao, China



Teng Jiang / Qingdao, China



Yael Hacohen / London, United Kingdom



Ruth Dobson / London, United Kingdom

Recipient: Trent Hodgson / Chicago, IL P2: Poster Session II Tuesday, April 29, 7:30 a.m. Subspecialization in Neurology: Historical Perspectives on Current Challenges



Marta Campagnolo / Padova, Italy

Saul R. Korey Award in Experimental Neurology



Dimitra Papadimitriou / Athens, Greece



Chiara Dalla Torre / Padova, Italy



Julieta Arena / Buenos Aires, Argentina



Alberto Martinez / Campinas, Sao Paulo



Francisco Varela / Buenos Aires, Argentina

Recipient: Jessica Shields / New Orleans, LA P2: Poster Session II Tuesday, April 29, 7:30 a.m. Probing the Interaction of the Ipsilateral Posterior Parietal Cortex with the Premotor Cortex Using a Novel Transcranial Magnetic Stimulation Technique



Jorge jesús Llibre / Havana, Cuba International Experience Monday, April 28, 1:00 p.m.



Roland P. Mackay Award in Historical Aspects

Minority Scholars Program

Sponsored by a grant from the Allergan Foundation. Recipients: Marcella Evans / University of California School of Medicine

Gregory R. Franklin, II / Medical University of South Carolina



Daniel A. Cristancho / Perelman School of Medicine at the University of Pennsylvania

Fast, Easy Registration Online  ·  AAN.com/view/AM14

19



2014 Award Recipients

Laura C. Ramirez / Temple School of Medicine

Palatucci Advocacy Leadership Forum Advocates of the Year



Jason Neal, PhD / Columbia University, College of Physicians and Surgeons

Sponsored by the AAN Government Relations Committee.



Shekinah Nefreteri Elmore / Harvard Medical School

Patient Safety Award



Julian Flores / Harvard Medical School

Sponsored by Professional Risk Management Services, Inc., management of The Neurologists’ Program.



H. Westley Phillips / Perelman School of Medicine University of Pennsylvania

Recipients: Shelly Ozark, MD / Charleston, SC Physician Patient Safety Award



Sara Dawit / University of Kansas School of Medicine



Catherine Elaine Norise / Perelman School of Medicine University of Pennsylvania

Movement Disorders Research Award

Sponsored by the American Academy of Neurology, the Parkinson’s Disease Foundation, and the AAN Movement Disorder Section and endowed by the Parkinson’s Disease Foundation. Recipient: Eduardo Tolosa, MD, PhD / Barcelona, Spain S27: Dystonia, Tremor, and Other Movement Disorders Wednesday, April 30, 2:00 p.m. Neuroscience Research Prize

Sponsored by the American Academy of Neurology, the American Brain Foundation, and the Child Neurology Society. Recipients: Charlotte Herber / Pound Ridge, NY Stefanie Henry / Brooklyn, NY Lisa Michaels / Plano, TX P3: Poster Session III Tuesday, April 29, 3:00 p.m. Child Neurology Neuroscience Research Prize

Recipient: Donn Dexter, MD, FAAN / Eau Claire, WI



Michael S. Pessin Stroke Leadership Prize

Sponsored by the American Academy of Neurology and endowed by Dr. Pessin’s family, friends, and colleagues. Recipient: Hooman Kamel, MD / New York, NY S51: Cerebrovascular Disease and Interventional Neurology: Large Vessel Atherosclerotic Disease Thursday, May 1, 1:00 p.m. Potamkin Prize for Research in Pick’s, Alzheimer’s, and Related Diseases

Sponsored by the American Academy of Neurology, the American Brain Foundation, and funded through the philanthropy of the Potamkin Family. Recipient: M. Marsel Mesulam, MD / Chicago, IL S8: Aging, Dementia, and Cognitive and Behavioral Neurology: PET Imaging Tuesday, April 29, 1:00 p.m. American Academy of Neurology President’s Award

Sponsored by the American Academy of Neurology. Recipient: Guy McKhann, MD / Baltimore, MD

Sponsored by the American Academy of Neurology, the American Brain Foundation, and the Child Neurology Society. Recipient: Laura Herman / Fort Lauderdale, FL Note: The recipient will attend the 43rd Child Neurology Society Annual Meeting in Columbus, OH

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Julio Rojas-Martinez, MD, PhD/ Dallas, TX Resident Patient Safety Award

2O14 Scientific Abstract Listing and Annual Meeting Information

Quality Award

H. Richard Tyler Award

Recipients: Dheeraj Khurana, MD / India Practicing Physician Quality Award

Sponsored by the American Academy of Neurology and the AAN Archive Committee.



Recipient: Edward J. Fine, MD, FAAN / Buffalo, NY

Laura Rosow, MD / San Francisco, CA Resident Quality Award

Kenneth M. Viste Jr., MD, Patient Advocate of the Year Award

Neuroendocrine Research Award

Sponsored by the American Academy of Neurology and supported by friends of Dr. Andrew Herzog. Recipient: Stafford Lightman, MB BCHir, MRCP, PhD, FRCP / Bristol, United Kingdom Bruce S. Schoenberg International Award in Neuroepidemiology

Endowed by gifts from Dr. Viste’s colleagues, friends, and patients. Recipient: Anthony G. Alessi, MD, FAAN / Norwich, CT Harold Wolff-John Graham: An Award for Headache/Facial Pain Research

Sponsored by the American Academy of Neurology and endowed by Endo Pharmaceuticals.

Endowed by GlaxoSmithKline, Inc. Recipient: Devender Bhalla, PhD / Limoges, France S10: HIV, PML, and Cerebral Malaria Tuesday, April 29, 1:00 p.m.

Recipient: Jakob Møller Hansen, MD, PhD / Los Angeles, CA S32: Headache: Basic Science and Imaging Wednesday, April 30, 2:00 p.m. Wayne A. Hening Sleep Medicine Investigator Award

Sleep Science Award

Sponsored by the American Academy of Neurology and the AAN Sleep Section and endowed by Cephalon, Inc. Recipient: Claudia Trenkwalder, MD / Kassel, Germany S9: Sleep Tuesday, April 29, 1:00 p.m.

Sponsored by the American Academy of Neurology and endowed by UCB, Inc.; Lilly USA; Elite Home Medical & Respiratory, Inc.; Raleigh Neurology Associates; and friends of Dr. Wayne A. Hening. Recipient: Aleksandar Videnovic, MD, MSc / Boston, MA S9: Sleep Tuesday, April 29, 1:15 p.m.

“[The Annual Meeting Science Programs] are amazing. The poster sessions are inspiring. You get these young researchers just starting, and they come out with beautiful things that just blow you away. ” Kathleen M. Fitzgerald, MD Eugene, OR



Fast, Easy Registration Online  ·  AAN.com/view/AM14 21



2014 Research Fellowships American Brain Foundation Clinical Research Training Fellowships

Cosponsored by the American Academy of Neurology and the American Brain Foundation. Recipients: Brian Edlow, MD Massachusetts General Hospital

Stefanie Geisler, MD Washington University, Saint Louis



Eyal Kimchi, MD, PhD Massachusetts General Hospital



Svjetlana Miocinovic, MD, PhD UT Southwestern Medical Center



Lidia Maria Moura, MD Massachusetts General Hospital



Peter Pressman, MD University of California San Francisco



Lucia Rivera Lara, MD Johns Hopkins University School of Medicine



Rainer von Coelln, MD, PhD University of Maryland School of Medicine

Susan S. Spencer Clinical Research Training Fellowship in Epilepsy

Cosponsored by the American Brain Foundation, the American Epilepsy Society, and the Epilepsy Foundation. Recipient: Colin Josephson, MD, MSc University of Calgary Clinical Research Training Fellowship in the Neurologic Application of Neurotoxins

Funded by the Allergan Foundation. Recipients: Srikant Rangaraju, MD Emory University

Valerie Rundle Gonzales, MD University of Florida College of Medicine

American Brain Foundation Practice Research Training Fellowship

Cosponsored by the American Academy of Neurology and the American Brain Foundation. Recipient: David Hwang, MD Yale School of Medicine

Clinical Research Training Fellowship in Ataxia

Cosponsored by the American Brain Foundation and the National Ataxia Foundation. Recipient: Padmaja Vittal, MD, MS Rush University Medical Center Clinical Research Training Fellowship in MS

Cosponsored by the American Brain Foundation and Biogen Idec. Recipient: Bardia Nourbakhsh, MD University of California San Francisco Robert Katzman, MD. Clinical Research Training Fellowship in Alzheimer’s Research

Cosponsored by the American Brain Foundation and the Alzheimer’s Association. Recipient: Elissios Karageorgiou, MD University of California San Francisco Clinician-Scientist Development Three-Year Award in Multiple Sclerosis

Cosponsored by the American Brain Foundation and the National Multiple Sclerosis Society. Recipient: Matthew Schindler, MD, PhD University of Pennsylvania Clinician-Scientist Development Three-Year Award in Myasthenia Gravis and Related Disorders of the Neuromuscular Junction

Cosponsored by the American Brain Foundation and the Myasthenia Gravis Foundation of America. Recipient: Ricardo Roda, MD, PhD New York University Clinician-Scientist Development Three-Year Award in Parkinson’s Disease

Cosponsored by the American Brain Foundation and the Parkinson’s Disease Foundation. Recipient: Amber Van Laar, MD University of Pittsburgh Medical Center Lawrence M. Brass Stroke Research Postdoctoral Fellowship

Cosponsored by the American Brain Foundation and the American Heart Association/American Stroke Association. Recipient: Amin Khalifeh Soltani, MD, MPH University of California San Francisco School of Medicine

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2O14 Scientific Abstract Listing and Annual Meeting Information

New! Clinical Research Track The outlined programs below are part of the new Clinical Research Track for the 2014 AAN Annual Meeting. For more information on the programs below, please visit the Annual Meeting Program Search at AAN.com/view/SearchAM. To register for the programs please visit: AAN.com/view/register.

Saturday, April 26 C7 Research Career Development Symposium: How to Be Successful in Academic Neuroscience 9:00 a.m.–5:00 p.m. This program is designed for academic neurologists who are early in the development of a clinician scientist career. The focus is on strategies for earning a mentored career development award.

Sunday, April 27 CQ2 Research and Technology Colloquium: From Discovery to Therapy 8:00 a.m.–12:00 p.m. Academic, industry, and regulatory representatives will address challenges in the drug development process from drug discovery through clinical trials. Faculty will facilitate a discussion with the attendees on how to advance laboratory findings to novel therapies. CQ4 Clinical Research Colloquium 1:00 p.m.–5:00 p.m. This colloquium provides a brief introduction to the clinical trial, the cohort study, and the case-control study with emphasis on their complementarities and their relative strengths and weaknesses.

Monday, April 28 C79 Strategic Grant Writing 10:00 a.m.–12:00 p.m. Faculty will emphasize strategies for devising strong lab- or patient-based research proposals, from establishing the importance of the research question to developing a strong, biologically based hypothesis, and demonstrating the capability of carrying the study to completion. Futures in Clinical Research Luncheon 12:00 p.m.–2:00 p.m. Provides information on a career in clinical research and an opportunity to interact with senior clinical researchers for students, residents, and fellows. Must sign up to attend. For more details and to register, contact Nate Kosher at [email protected].

Tuesday, April 29 Futures in Clinical Research Luncheon Mentoring Sessions 12:00 p.m.–1:30 p.m. Mentoring sessions for students, residents, and fellows in seven subspecialty areas: Child Neurology, Epilepsy, Headache, Multiple Sclerosis, Muscular Dystrophy, Neurocritical Care, and Parkinson’s Disease. Must sign up to attend.

I5 Revolution of Genetic Tools and the Impact on Neurology 1:00 p.m.–5:00 p.m. This program will provide an integrative journey through the revolution in molecular genetics and associated technologies and their immediate and long-term applications, including a broad perspective on the promise genomic medicine holds, an introduction to the spectrum of genomic information that can be interrogated, perspectives on ethical challenges, and the practical perspective of a neurologist using genomic information.

Wednesday, April 30 I8 Clinical Decision Making After the Dust Settles on Clinical Trials 2:00 p.m.–6:00 p.m. Once a trial establishing the efficacy of a new treatment is published, many questions remain to be answered before a neurologist can apply that new knowledge in a way to produce the full health benefit for individual patients and across that neurologist’s entire practice. In this session, research in key areas that are critical to consider is illustrated, and the current status of each of these areas in neurology is summarized.

For more details and to register, contact Nate Kosher at [email protected].

Included with registration Registration fee required

April 26 – May 3, 2014 Philadelphia, PA



Annual Meeting Program Schedule For full course information please reference the 2014 Annual Meeting Registration and Advance Program or view the Annual Meeting Program Search at AAN.com/view/SearchAM.

Saturday, April 26 8:00 a.m.–12:00 p.m. Clinical Approach to Muscle Disease   C1 How to Analyze Spells by Video-EEG   C2 Assessment of Rapidly Progressive Dementias   C3 and Related Neurologic Conditions Resident Basic Science I: Neuropathology   C4 9:00 a.m.–5:00 p.m. Clerkship and Program Directors Conference   C5 The Practice of Neurology: Issues in   C6 Coding and Reimbursement Research Career Development Symposium:   C7 How to Be Successful in Academic Neuroscience 1:00 p.m.–5:00 p.m. Evaluation and Management of Autonomic Disorders   C8 Differential Diagnosis of Neurologic Infections   C9   C10 Approach to Sleep Symptoms: Sleepy or Sleepless   C11 Resident Basic Science II: Neuroanatomy 2:00 p.m.–5:00 p.m.   CQ1 BRAINS Colloquium: Understanding and Improving Your Bottom Line 3:00 p.m.–5:00 p.m.   C12 The Dystonias: Diagnosis, Treatment, and Update on Causes   C13 Practice Survival for Neurologists: Business Strategies for Success   C14 Preventing a First Stroke: What Every Neurologist Needs to Know   C15 Top 10 Neuro-ophthalmic Diagnoses You Can’t Afford to Miss   C16 Multiple Sclerosis Essentials   C17 Attention Deficit Hyperactivity Disorder Across the Lifespan   C18 Therapy of Headache   C19 Controversies in Brain Death Determination

Sunday, April 27 6:30 a.m.–8:00 a.m.   C20 Neuro Flash: MRI and Multiple Sclerosis   C21 Neuro Flash: Acute Stroke Management   C22 You Make the Call—An Interactive, Multimedia, Case-based Approach to Learning EMG

24

  C23

Hyperkinetic Movement Disorders: Diagnosis and Treatment   C24 Global Health Challenges: Neurology in Developing Countries   C25 Creativity   C26 Introduction to Genetics 8:00 a.m.–12:00 p.m.   CQ2 Research and Technology Colloquium: From Discovery to Therapy 8:00 a.m.–12:00 p.m.   C27 Clinical EMG I   C28 Botulinum Toxins: Practical Issues and Clinical Uses for Neurologists   C29 Multiple Sclerosis Overview I: Basic and Translational Science C30 Sleep for the Practicing Neurologist      C31 Resident Basic Science III: Neuropharmacology   C32 Child Neurology I   C33   Prevention of Cardioembolic Stroke in Patients with Nonvalvular Atrial Fibrillation: Recommendations Based on Evidence-based Guidelines and Recent Randomized Trials   C34 Neuroimaging for the General Neurologist: Brain   C35  Life Reimagined   I1   Temporal Lobe Epilepsy and Febrile Seizures . . 42 9:00 a.m.–12:00 p.m.   CQ3 Patient Safety Colloquium 9:00 a.m.–12:00 p.m.   C36 EEG in Children: Developmental Maturation, Variants, Epilepsy Syndromes, and Identification of Surgical Candidates 9:00 a.m.–5:00 p.m.   C37 Therapy in Neurology   C38 Neurologic Intensive Care   C39 Neuro-ophthalmology   C40 Spine Neurology: Assessment and Management of Common Spine Disorders   C41 Neurophysiologic Intraoperative Monitoring Skills Workshop 10:00 a.m.–12:00 p.m.   C42 Vascular Cognitive Impairment and Dementia: Current Status and Future   C43 E/M: Minimize Mistakes, Maximize Reimbursement   C44 Update on Ataxias

2O14 Scientific Abstract Listing and Annual Meeting Information

  Subspecialty in Focus Track  Leadership Development

1:00 p.m.–2:30 p.m.   S1 Section Topic Controversies:  ICU EEG Monitoring—Seizures in Critically Ill Patients . 42 1:00 p.m.–5:00 p.m.   CQ4 Clinical Research Colloquium 1:00 p.m.–5:00 p.m.   C45 Clinical EMG II   C46 Non-Alzheimer’s Dementia   C47 Multiple Sclerosis Overview II: Clinical Advances   C48 Autoimmune Neurology   C49 Child Neurology II   C50 Core Concepts in Pain Management   C51   Algorithms in the Diagnosis and Treatment of Epilepsy   C52 Neuroimaging for the General Neurologist: Spine and Peripheral Nerve   C53 Clinical Usefulness of Botulinum Toxin and Treatment of Dystonia Skills Pavilion   I2   New Antithrombotic Agents for Stroke Prevention . . . . . . . . . . . . . . . . . . . . . . 43 2:00 p.m.–5:00 p.m.   CQ5 Practice Colloquium: How to Navigate and Succeed in New Payment Models

  Included with registration   Registration fee required

7:00 a.m.–8:30 a.m.   State Society Leadership Roundtable Leadership representatives of state neurological societies are invited to discuss challenges, strategies, and practices related to state society creation and maintenance. Discussion will be facilitated by Academy staff. Participants will learn from the experiences of established societies and be introduced to the resources available from the Academy. 8:00 a.m.–8:30 a.m.     A AN/AANI Business Meeting All members are invited to attend the meeting to take part in the Academy business. 8:00 a.m.–12:00 p.m.   C62 Continuum ® Test Your Knowledge: A Multiple-Choice Question Review   C63 Primer of Behavioral Neurology   C64 Introduction to Primary Headache Disorders   C65 Neurologic Complications of Systemic Cancer   C66 Teleneurology and Technologies   C67 Infections of the Nervous System I: Common Infections   C68   Stroke in Childhood and Adolescence   I3   Clocks, Sleep, Brain Health and Disorders:  Impact on Mechanism, Expression, and Treatment . . . 44

6:00 p.m.–10:00 p.m.   Opening Party . . . . . . . . . . . . . . . . . . . . . . . . . . . . 136 Join your friends and colleagues for an exciting evening filled with entertainment. Each registered meeting attendee will receive one free ticket to these events. Guest tickets are available through registration for $50.

8:30 a.m.–12:00 p.m.   CQ6 Education Colloquium

Monday, April 28

9:00 a.m.–5:00 p.m.   C71 Movement Disorders   C72 Neurology Update I   C73 Clinical EEG   C74 Genetics in Neurology C75     Women in Leadership (must apply)   C76 EMG Skills Workshop: Basic

6:30 a.m.–8:00 a.m.   C54 Morning Report: Lumbar Radiculopathy, Lumbar Spinal Stenosis, Low Back Pain, and Post-Laminectomy Syndrome   C55 Morning Report: Memory Disorders   C56 Neuro Flash: Neuro-ophthalmology   C57 Small Fiber Neuropathies: Sensory, Autonomic and Both   C58 Hallucinations in Parkinson’s Disease   C59 Career Development for Clinician Educators   C60 Prognostication in the Era of Hypothermia 6:30 a.m.–8:30 a.m.   C61 Resident and Fellow Career Breakfast: The Early Years (registration is required)



9:00 a.m.–12:00 p.m.   C69 Improving Accuracy of Dementia Diagnosis: Case Studies with Both Imaging and Neuropathology   C70 Controversies in Multiple Sclerosis Therapy

9:30 a.m.–12:00 p.m.   C77 Philanthropy 101 10:00 a.m.–12:00 p.m.   C78 Tales from the Front Cover: Effective Book Writing and Publishing for Neurologists   C79 Strategic Grant Writing 12:00 p.m.–1:30 p.m.    Government Relations Committee Meet and Greet

Fast, Easy Registration Online  ·  AAN.com/view/AM14 25



Annual Meeting Program Schedule 1:00 p.m.–2:30 p.m.    S2 Cancelled

9:00 a.m.–12:00 p.m.   Presidential Plenary Session . . . . . . . . . . . . . 64

1:00 p.m.–5:00 p.m.   C80 Stroke in Young Adults   C81 Chronic Migraine Education Program   C82 Sports Neurology: Non-Concussion Overview   C83 Infections of the Nervous System II: Advanced and Emerging Infections   C84   Sleep Principles Applied to Neurological Disease   C85  Improving Your Leadership Skills: A Practical Approach   I4   Recent Advances in Translational Research in Autism . . . . . . . . . . . . . . . . . . . . . 45

F eatures the AAN’s premier lecture awards for clinically relevant research and a presentation by a leading lecturer. Top researchers speak on some of the most significant findings in neurology in 2014.

1:30 p.m.–3:00 p.m.    AAN/ABPN MOC Informational Session 2:00 p.m.–4:30 p.m.   CQ7 Education Research Colloquium

Presidential Lecture:

James L. Bernat, MD, FAAN Dartmouth Hitchcock Medical Center, Lebanon, NH Challenges to Ethics and Professionalism Facing the Contemporary Neurologist



George C. Cotzias Lecture: Endowed by Roche Pharmaceuticals.

Stefan M. Pulst, MD, FAAN University of Utah, Salt Lake City, UT Degenerative Ataxias: From Genes to Therapies  Sidney Carter Award in Child Neurology Lecture: Endowed by an anonymous donor.

Darryl C. De Vivo, MD, FAAN Columbia University Medical Center, New York, NY Rare Diseases and Neurological Phenotypes

2:00 p.m.–5:00 p.m.   CQ8 Health Information Technology Colloquium: Advancements in Technology 2:00 p.m.–5:00 p.m.   C86 ICD-10-CM: Essentials of Understanding and Implementation   C87 Eye Movement Disorders: A Systematic Approach to the Evaluation of Diplopia 3:00 p.m.–6:30 p.m. Poster Session I . . . . . . . . . . . . . . . . . . . . 48–55   P1 4:30 p.m.–6:30 p.m. Exhibit Hall Opening Reception 6:30 p.m.–9:00 p.m. Residents and Fellows Career Forum and Reception

Tuesday, April 29

 Robert Wartenberg Lecture:

David M. Holtzman, MD, FAAN Washington University School of Medicine, St. Louis, MO Alzheimer’s Disease in 2014: Mapping a Road Forward 11:30 a.m.–5:00 p.m.   Exhibit Hall 1:00 p.m.–2:30 p.m.   S3 Section Topic Controversies: PFO: Aggressive Treatment or Just Aspirin . . . . . . . . 65 1:00 p.m.–2:45 p.m.    Scientific Platform Sessions . . . . . . . . . . . . . . . 66–67   S4 MS and CNS Inflammatory Disease: Clinical Trials

6:30 a.m.–8:30 a.m.   2014 AAN Run/Walk for Brain Research . . . . 137 6:30 a.m.–8:00 a.m.   C89 Neuro Flash: Epilepsy   C90 Therapy of Multiple Sclerosis   C91 Advances in Autism Spectrum Disorders and Intellectual Disability: From Genetics to Clinical Practice C92 The Neurology of Social Behavior      C93 Therapy of Neuromuscular Disease   C94 Borderlands of Neurology and Internal Medicine 7:30 a.m.–11:00 a.m.   P2 Poster Session II . . . . . . . . . . . . . . . . . . . . 56–63 26

  S5 Cerebrovascular Disease and Interventional Neurology:

Pre-hospital, Telemedicine, and Related Topics   S6 Neuromuscular Disease: Gene Therapy    S7 Parkinson’s Disease: Preclinical and Clinical Therapeutics   S8 Aging, Dementia, and Cognitive and Behavioral Neurology: PET Imaging

¡¡ Presentation of the Potamkin Prize for Research in Pick’s, Alzheimer’s Disease, and Related Diseases    S9 Sleep ¡¡ Presentation of the Sleep Science Award ¡¡ Presentation of the Wayne A. Hening Sleep Medicine Investigator Award

2O14 Scientific Abstract Listing and Annual Meeting Information

  Subspecialty in Focus Track  Leadership Development

   S10 HIV, PML, and Cerebral Malaria

¡¡ Presentation of the Bruce S. Schoenberg International Award in Neuroepidemiology   S11 Neuro Trauma, Critical Care, and Sports Neurology   S12 Cerebrovascular Disease and Interventional Neurology: Epidemiology and Risk Factors   S13 MS and CNS Inflammatory Disease: MRI Atrophy Measures and Correlations 1:00 p.m.–5:00 p.m.   C95 Deep Brain Stimulation Management   C96 The History of Certain Disorders of the Nervous System   C97 Emergency Neurology   C98 Practical Legal Issues for Neurologists   C99 Epilepsy Skills Pavilion   I5 Revolution of Genetic Tools and the Impact on Neurology . . . . . . . . . . . . . . . . . . 68   I6 Peripheral Neuropathies . . . . . . . . . . . . . . . . . . 69 2:00 p.m.–5:00 p.m.   C100 The Intractable Headache Patient 3:00 p.m.–6:30 p.m. Poster Session III . . . . . . . . . . . . . . . . . . . . 70–77   P3 3:15 p.m.–5:00 p.m.    Scientific Platform Sessions . . . . . . . . . . . . . . . . 78–79   S14 MS and CNS Inflammatory Disease: Animal and In Vitro   S15   S16    S17   S18    S19    S20

Studies Cerebrovascular Disease and Interventional Neurology: Clinical and Imaging Biomarkers and Genetics Neuromuscular and Clinical Neurophysiology (EMG): Clinical Trials and Therapy Parkinson’s Disease: Genetics and Epidemiology Aging, Dementia, and Cognitive and Behavioral Neurology: Behavioral Neuroscience Neuro-ophthalmology/Neuro-otology I Pain and Palliative Care

¡¡ Presentation of the Mitchell B. Max Award for Neuropathic Pain   S21 Neurorehabilitation and Neural Repair   S22 Neuro-oncology   S23 MS and CNS Inflammatory Disease: Novel Therapeutics ¡¡ Presentation of the John Dystel Prize for Multiple Sclerosis Research

  Included with registration   Registration fee required

5:30 p.m.–6:30 p.m.   Hot Topics Plenary Session . . . . . . . . . . . . . . 80 Features translational research related to clinical issues of

importance. Four outstanding physician-scientists provide summaries of their recent research findings and describe the clinical implications of the results. Oleg Butovsky, PhD Brigham and Women’s Hospital/Harvard Medical School, Boston, MA Identification of a Unique Molecular and Functional Microglia Signature in Health and Disease Jerome H. Chin, MD, PhD, MPH Alliance for Stroke Awareness and Prevention Project (ASAPP), San Anselmo, CA The Global Epidemic of Stroke: Sounding the Alarm Dennis W. Dickson, MD Mayo Clinic, Jacksonville, FL Emerging Concepts in Chronic Traumatic Encephalopathy David Eidelberg, MD, FAAN Feinstein Institute for Medical Research, Manhasset, NY Functional Connectivity and Functional Imaging in Movement Disorders 7:00 p.m.–10:00 p.m.   Corporate Therapeutic Updates . . . . . . . . . . . . . . . 147  Industry-sponsored, non-CME programs will be offered and are

open to attendees at no charge. They will provide an opportunity for pharmaceutical companies, device companies, or other neurologicrelated organizations to share information regarding their current therapies and projects in the pipeline in accordance with standards set for industry by the FDA.

Wednesday, April 30 6:30 a.m.–8:00 a.m.   C101 Neuro Flash: Child Neurology   C102 Balance and Gait Disorders   C103 Therapy of Stroke   C104 Nystagmus: An Organized Approach   C105 Differential Diagnosis of Dementia: Linking Clinical Syndromes to Biomarkers   C106 Integrative Management of Multiple Sclerosis   C107 Brain Computer Interfaces: Frontiers in Neurology and Neuroscience 7:30 a.m.–11:00 a.m.   P4 Poster Session IV . . . . . . . . . . . . . . . . . . . . 81–88



Fast, Easy Registration Online  ·  AAN.com/view/AM14

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Annual Meeting Program Schedule 9:00 a.m.–12:00 p.m.   Contemporary Clinical    Issues Plenary Session . . . . . . . . . . . . . . . . . 89 Highlights issues most critical to practicing neurologists, including

abstracts related to new therapeutic developments, clinical applications of basic and translational research, and innovative technical developments.







William K. Mountford, PhD Premier Research Services, Wilmington, NC Comparison of Thrombolytic Treatment for Acute Ischemic Stroke Pre- and Post-Telemedicine Implementation in the Spoke Hospital Setting Discussant: Lee H. Schwamm, MD Massachusetts General Hospital, Boston, MA

David R. Jacoby, MD, PhD BioMarin Pharmaceutical Inc., Novato, CA Epigenetic Therapy for Friedreich’s Ataxia: A Phase I Clinical Trial

   Scientific Platform Sessions . . . . . . . . . . . . . . . 90–91   S24 Diet and Hormonal Influences in MS   S25 Cerebrovascular Disease and Interventional Neurology:

Hemorrhage, Aneurysms, and Vascular Malformations   S26 Biomarkers in Neuromuscular Diseases    S27 Dystonia, Tremor, and Other Movement Disorders

  S28

   S29

   S30

William Herring, MD, PhD Merck Research Laboratories, North Wales, PA Clinical Profile of the Orexin Receptor Antagonist Suvorexant for the Treatment of Insomnia in Phase-3 Clinical Trials Discussant: Phyllis C. Zee, MD, PhD Northwestern University Medical School, Chicago, IL

  S31



Jonathan Stone, MB, ChB, FRCP, PhD Western General Hospital, Edinburgh, United Kingdom Functional (Psychogenic) Disorders in Neurology

Kenneth L. Marek, MD Institute for Neurodegenerative Disorders, New Haven, CT Parkinson’s Disease Progression Marker Initiative:  Developing a Translational Toolbox for PD Progression Commentary and discussion follow each presentation. 11:30 a.m.–5:00 p.m.   Exhibit Hall 28

2:00 p.m.–3:45 p.m.

Discussant: Tetsuo Ashizawa, MD, FAAN University of Florida, Gainesville, FL

David B. Goldstein, PhD Duke University, Durham, NC Direct to Consumer Genetic Testing



12:00 p.m.–1:30 p.m. American Academy of Neurology and American Brain Foundation Awards Luncheon . . . . . 137

  S32

  S33

¡¡ Presentation of the Movement Disorders Research Award Aging, Dementia, and Cognitive and Behavioral Neurology: Dementia Genetics ¡¡ Presentation of the Norman Geschwind Prize in Behavioral Neurology Epilepsy and Clinical Neurophysiology: Inflammation, Status Epilepticus, and Genetics ¡¡ Presentation of the Dreifuss-Penry Epilepsy Award Education, Research, and History ¡¡ Presentation of the Lawrence C. McHenry Award: An Award for the History of Neurology ¡¡ Presentation of the S. Weir Mitchell Award General Neurology I Headache: Basic Science and Imaging ¡¡ Presentation of the Harold Wolff-John Graham Award: An Award for Headache/Facial Pain Research Cognition Fatigue in MS

2:00 p.m.–6:00 p.m.   C108 Neurologic Issues in Pregnancy   C109 Emergency Room Neuro-ophthalmology   C110 Sports Concussion and Other Mild Concussive Injuries   C111 Bedside Evidence-based Medicine: How to Deconstruct Articles in Order to Take Care of Patients   C112 Neuromuscular Bedside Rounds Skills Pavilion   C113 Acute Stroke Alert Skills Pavilion   I7 Emerging Therapeutic Advances in Multiple Sclerosis . . 92   I8 Clinical Decision Making After the Dust Settles on Clinical Trials . . . . . . . . . . . . . . . 93 3:00 p.m.–6:30 p.m. Poster Session V . . . . . . . . . . . . . . . . . . . .94–101   P5 4:00 p.m.–5:45 p.m.   Platform Blitzes . . . . . . . . . . . . . . . . . . . . . . 102–103   S34 MS and CNS Inflammatory Disease: Risk Factors for MS Disease and Course   S35 Cerebrovascular Disease and Interventional Neurology: Issues in Acute Treatment

2O14 Scientific Abstract Listing and Annual Meeting Information

  Subspecialty in Focus Track  Leadership Development

  S36 Neuromuscular Disease: Clinical    S37 Clinical Aspects of Parkinson’s Disease   S38 Aging, Dementia, and Cognitive and Behavioral Neurology:    S39    S40   S41   S42   S43

Plasma and Other Biomarkers Neuro-ophthalmology/Neuro-otology II General Neurology II Headache: Clinical Child Neurology I Epilepsy and Clinical Neurophysiology (EEG): Cognition

5:30 p.m.–7:00 p.m.   Current Practice Issues in Neurology

The interactive Current Practice Issues in Neurology session “Do Payer Rankings Keep You at the Top of the Class or Give You a Failing Grade” will give neurologists a chance to hear directly from both a CMS Medical Officer and a private payer Medical Director to gain a better understanding of how to properly interpret their details from the Quality and Resource Use Reports (QRUR) and physician designation programs; how to determine if the information is accurate; the importance of ensuring your rating is accurate; what the steps to take are if there are discrepancies with their information; and navigate through and utilize the CMS Physician Compare website and other available resources. The Academy is pleased to offer this event to continue developing a positive, constructive dialogue with payers at the physician level.

Thursday, May 1 6:30 a.m.–8:00 a.m.   C114 Morning Report: Multiple Sclerosis   C115 Neuro Flash: Palliative Care for the Practicing Neurologist   C116 Learning Movement Disorders in Hindsight: Lessons from My Patients C117 Principles of Genomic Medicine: Whole Exome    Sequencing in Neurologic Disease   C118 Neurotoxicology   C119 Syndromes of Autonomic Dysfunction in Children and Adolescents 7:30 a.m.–11:00 a.m.   P6 Poster Session VI . . . . . . . . . . . . . . . . . . . 104–111 9:00 a.m.–12:00 p.m.   Frontiers in Neuroscience Plenary Session . . 112 Focuses on translational research related to clinical issues of

importance. Six physician scientists outline their recent research findings, along with the clinical implications.



6:00 p.m.–7:00 p.m.

  Included with registration   Registration fee required

   Highlights in the Field Sessions

S . Thomas Carmichael, MD, PhD David Geffen School of Medicine at UCLA, Los Angeles, CA Tissue Environments for Brain Repair Albert Lo, MD, PhD

  H1 Child Neurology

Brown University, Providence VA Medical Center, Providence, RI Opportunities and Challenges of Robot Assisted and Facilitated Neurorecovery

  H2 Epilepsy   H3 Geriatric   H4 Headache & Facial Pain 

  H5 Movement Disorders   H6 Multiple Sclerosis    H7 Neural Repair & Rehabilitation

William Seeley, MD UCSF, San Francisco, CA Network-based Neurodegeneration

  H8 Neuro-oncology Cori Bargmann, PhD

   H9 Neuro-ophthalmology/Neuro-otology

Rockefeller University, New York, NY Using Fixed Circuits to Generate Flexible Behaviors

   H10 Sleep   H11 Sports Neurology

6:00 p.m.–7:30 p.m.   Emerging Science Session



7:00 p.m.–10:00 p.m.   Corporate Therapeutic Updates . . . . . . . . . . . . . . . 147  Industry-sponsored, non-CME programs will be offered and are

open to attendees at no charge. They will provide an opportunity for pharmaceutical companies, device companies, or other neurologic-related organizations to share information regarding their current therapies and projects in the pipeline in accordance with standards set for industry by the FDA.





Bruce R. Rosen, MD, PhD Harvard Medical School, Boston, MA Advances in Mapping Human Brain Connectivity: The Human Connectome Project  aiken Nedergaard, MD, DMSc M University of Rochester Medical Center, Rochester, NY The Nightlife of Astrocytes

Fast, Easy Registration Online  ·  AAN.com/view/AM14

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Annual Meeting Program Schedule 11:30 a.m.–3:00 p.m.   Exhibit Hall 1:00 p.m.–2:45 p.m.    Scientific Platform Sessions . . . . . . . . . . . . . . 114–115   S44 MS and CNS Inflammatory Disease: Neuroimaging I   S45 Cerebrovascular Disease and Interventional Neurology:

Rehabilitation, Recovery, and Complications   S46 Neuromuscular Disease: Genetics, Pathogenesis, and Measures    S47 Movement Disorders: Huntington’s Disease, Ataxia, and Wilson’s Disease

¡¡ Presentation of the Jon Stolk Award in Movement Disorders for Young Investigators   S48 Aging, Dementia, and Cognitive and Behavioral Neurology: MRI Imaging    S49 Practice, Policy, and Ethics    S50 Epilepsy and Clinical Neurophysiology (EEG): Electrophysiology, Imaging and Functional Connectivity ¡¡ Presentation of the Founders Award   S51 Cerebrovascular Disease and Interventional Neurology: Large Vessel Atherosclerotic Disease ¡¡ Presentation of the Michael S. Pessin Stroke Leadership Prize   S52 General Neurology III   S53 MS and CNS Inflammatory Disease: Biomarkers and Therapeutic Mechanisms 1:00 p.m.–5:00 p.m.   C120 Consultations in the Medical Surgical ICU   C121 Office Orthopedics for the Neurologist   C122 Traumatic Brain Injury   C123 Neuro-ophthalmology and Neurovestibular Exam Lab Skills Pavilion   I9 Emerging Concepts in Headache Therapy . . . . . . . . 116   I10 The Global Burden of Neurological Diseases . . . . . . . 117

   S59 Epilepsy and Clinical Neurophysiology (EEG):

Reproduction, Health Care Delivery, and Co-morbidities

   S60 Child Neurology II   S61 Muscle Disease: Gene Therapy and Models   S62 Cerebrovascular Disease and Interventional Neurology:

Cognitive and Behavioral   S63 Neuromyelitis Optica and Autoimmune Encephalitis 5:30 p.m.–6:30 p.m.    Highlights in the Field Sessions   H12 Adult Intellectual and Developmental Disabilities   H13 Endovascular and Interventional Neurology, and

Stroke and Vascular Neurology   H14 Women’s Issues in Neurology   H15 Critical Care

5:30 p.m.–7:00 p.m.   Controversies in Neurology Plenary Session . . 128 The program features experts discussing the most current and controversial issues in neurology. It is set up as a series of debates in which two speakers argue opposing sides of a single topic, followed by a rebuttal. Each round concludes with a 10-minute question and answer period. Does Preventing Relapses Protect Against Progressive MS? Pro: Maria Trojano, MD University of Bari, Bari, Italy Con: Helen Tremlett, PhD, BPharm University of British Columbia, Vancouver, BC, Canada Is Intervention for Asymptomatic AVM Useful? Pro: Robert M. Friedlander, MD UPMC Presbyterian, Pittsburgh, PA

2:00 p.m.–5:00 p.m.   C124 Clinical E-Pearls   C125 Status Epilepticus

Con: J. P. Mohr, MD, FAAN Columbia University, New York, NY

3:00 p.m.–6:30 p.m. Poster Session VII . . . . . . . . . . . . . . . . . . 118–125   P7

Should Neurologists Prescribe Marijuana for Neurological Disorders? Pro: Barbara S. Koppel, MD, FAAN Metropolitan Hospital, Rye, NY

3:15 p.m.–5:00 p.m.    Scientific Platform Sessions . . . . . . . . . . . . . . 126–127   S54 MS and CNS Inflammatory Disease: Neuroimaging II   S55 Pediatric Stroke and Stroke in the Young   S56 Anterior Horn Disease

¡¡ Presentation of the Sheila Essey Award: An Award for ALS Research    S57 Movement Disorders: Imaging   S58 Aging, Dementia, and Cognitive and Behavioral Neurology: Clinical Aspects 30



2O14 Scientific Abstract Listing and Annual Meeting Information

Con: John C. M. Brust, MD, FAAN Columbia University, New York, NY

  Subspecialty in Focus Track  Leadership Development

6:00 p.m.–9:00 p.m.   C126 Case Studies: Unusual Diagnostic and Management of Cases in Neuromuscular Disease   C127 Case Studies: Unusual Movement Disorders   C128 Case Studies in Behavioral Neurology: Focus on Frontotemporal Degeneration   C129 Case Studies: Multiple Sclerosis   C130 Case Studies: Neurologic Consultations in Cancer Patients C131 Test Your Knowledge: A Case-based    Approach to Neuroimaging

Friday, May 2 6:30 a.m.–8:00 a.m.   C132 Neuro Flash: Approach to Acute CNS Infections   C133 The Spectrum of Motor Neuron Disease   C134 Parkinson’s Disease Management: Pearls, Pitfalls, and Future Prospects C135 Continued Challenges of the    Neurohospitalist Model of Care   C136 Important Drug Interactions for Neurologists and Psychiatrists   C137 Mild Cognitive Impairment: Implications for Clinicians 8:00 a.m.–12:00 p.m.   C138 Parkinson’s Disease and Movement Disorders Update   C139 Neuromyelitis Optica: Scientific and Clinical Update   C140 Hot Topics in Headaches and Related Disorders   C141 Neurodevelopmental Disabilities Across the Lifespan   C142   Concussion in the Military and in Sports   I11   Proteinopathy in Neurodegenerative Disease . 130 9:00 a.m.–5:00 p.m.   C143 Peripheral Neuropathy   C144 Neurology Update II   C145 Cerebrovascular Disease   C146 Clinical Epilepsy   C147 Dementia Update   C148 Neuromuscular Ultrasound Skills Workshop

  Included with registration   Registration fee required

12:00 p.m.–1:30 p.m.   Clinical Trials Plenary Session . . . . . . . . . . . . 131 This mid-day session covers important clinical topics that affect patient care identified from other society meetings. The latest updates within several clinical trials conducted over the course of the last year will be presented with an open panel discussion at the conclusion. Michael Wall, MD, FAAN University of Iowa, Iowa City, IA The Idiopathic Intracranial Hypertension Treatment Trial: A Multicenter, Double-Blind, Randomized Clinical Trial Comparing Acetazolamide and Placebo on Visual Outcome Mark R. Gilbert, MD The University of Texas MD Anderson Cancer Center, Houston, TX Anti-angiogenic Therapy for Glioblastoma: A Randomized, Double-Blinded Phase III Trial of Bevacizumab in Newly Diagnosed Patients Aaron E. Miller, MD, FAAN Mt. Sinai School of Medicine, New York, NY TOPIC: Efficacy and Safety of Once-daily Oral Teriflunomide in Patients with First Clinical Episode Consistent with Multiple Sclerosis Jeffrey L. Saver, MD, FAAN UCLA School of Medicine, Los Angeles, CA FAST-MAG Trial in Acute Ischemic Stroke

David Dodick, MD Mayo Clinic, Phoenix, AZ CGRP Monoclonal Antibody LY2951742 for the Prevention of Migraine: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study Peter Goadsby, MD, PhD University of California, San Francisco, CA Randomized, Double-blind, Placebo-controlled Trial of ALD403: An Anti-CGRP Peptide Antibody in the Prevention of Frequent Episodic Migraine 1:00 p.m.–2:30 p.m.   S64 Section Topic Controversies: Pain: Methods of Treatment . . . . . . . . . . . . . . . . 132 1:00 p.m.–5:00 p.m.   C149 Neuro-otology   C150 Neuro-oncology: Primary Brain Tumors   C151 Hot Topics in Sleep Neurology   C152 Symptomatic Management in Multiple Sclerosis   C153   Imaging and Genomics for Detecting Neurodegenerative Proteinopathy in Clinical Practice   I12   Concussion in Sports and the Military . . . . . 132



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31



Annual Meeting Program Schedule 5:30 p.m.–7:00 p.m.   Neurology Year in Review Plenary Session . . 133 This plenary session will feature six speakers, each focusing on the latest research that has happened in the last year within a specific subspecialty topic. Anne H. Cross, MD Washington University School of Medicine, St. Louis, MO Multiple Sclerosis Peter Goadsby, MD, PhD UCSF, San Francisco, CA Headache/Pain Robert C. Griggs, MD, FAAN University of Rochester, Rochester, NY Neuromuscular Kathleen M. Shannon, MD Rush University Medical Center, Chicago, IL Movement Disorders David M. Greer, MD Yale University School of Medicine, New Haven, CT Neurocritical Care Todd E. Golde, MD, PhD University of Florida Collage of Medicine, Gainesville, FL Alzheimer’s Disease 7:30 p.m.–9:00 p.m.   Closing Party . . . . . . . . . . . . . . . . . . . . . . . . . . . 136 Join us at the festive Closing Party, where former NFL star-turnedsinger and Public Leadership in Neurology Award-winner Ben Utecht will enchant you with his inimitable vocal stylings.

Saturday, May 3 6:30 a.m.–8:00 a.m.   C154 Update on Endovascular Treatment of Cerebrovascular Diseases   C155 Cumulative Sports Concussion and Risk of Dementia   C156 Evaluation and Therapy of Restless Legs Syndrome and Periodic Limb Movements in Sleep C157 Therapy of Epilepsy      C158 Psychogenic Movement Disorders 6:30 a.m.–8:30 a.m.   C159 Challenging Headache Cases 8:00 a.m.–12:00 p.m.   C160 Neuromuscular Junction Disorders   C161 Neurologic Complications of Medical Disease   C162 Diagnostic Dilemmas in Multiple Sclerosis   C163 Myelopathies   C164 Practical Psychopharmacology for Neurologists   C165 Critical Care EEG Monitoring 9:00 a.m.–12:00 p.m.   C166 Interpretation of Polysomnography for the Practicing Neurologist 10:00 a.m.–12:00 p.m.   C167 Mitochondrial Disorders in Neurology   C168 Therapy of Movement Disorders: A Case-based Approach   C169 Common Neurologic Problems in Adults with Intellectual and Developmental Disabilities

Current as of 2/13/2014 –Subject to change

“With every Annual Meeting that I attend I always come away from the scientific conferences with something new and different to add to my care and treatment of patients with neurologic diseases.” Christopher J. Prusinski, DO Melbourne, FL

32

2O14 Scientific Abstract Listing and Annual Meeting Information



Annual Meeting Programs by Topic For full course information please reference the 2014 Annual Meeting Registration and Advance Program or view the Annual Meeting Program Search at AAN.com/view/SearchAM. Please refer to the key for the following program definitions: C Course P  Poster Session

CQ Colloquium H  Highlights in the Field S  Scientific Platform Session/Section Topic Controversies

Aging, Dementia, Cognitive, and Behavioral Neurology   C3

Assessment of Rapidly Progressive Dementias and Related Neurologic Conditions   C17 Attention Deficit Hyperactivity Disorder Across the Lifespan C25 Creativity      C42 Vascular Cognitive Impairment and Dementia: Current Status and Future   C46 Non-Alzheimer’s Dementia   C55 Morning Report: Memory Disorders   C63 Primer of Behavioral Neurology   C69 Improving Accuracy of Dementia Diagnosis: Case Studies with Both Imaging and Neuropathology P1 Poster Session I . . . . . . . . . . . . . . . . . . . . 48–55      C92 The Neurology of Social Behavior Poster Session II . . . . . . . . . . . . . . . . . . . . 56–63   P2 Presidential Plenary Session . . . . . . . . . . . . . 64 Aging, Dementia, and Cognitive and   S8 Behavioral Neurology: PET Imaging . . . . . . . . . . . . 66 Poster Session III . . . . . . . . . . . . . . . . . . . . 70–77   P3 S18 Aging, Dementia, and Cognitive and    Behavioral Neurology: Behavioral Neuroscience . . . . . 78   C105 Differential Diagnosis of Dementia: Linking Clinical Syndromes to Biomarkers Poster Session IV . . . . . . . . . . . . . . . . . . . . 81–88   P4   S28 Aging, Dementia, and Cognitive and Behavioral Neurology: Dementia Genetics . . . . . . . . 90 Poster Session V . . . . . . . . . . . . . . . . . . . .94–101   P5   S38 Aging, Dementia, and Cognitive and Behavioral Neurology: Plasma and Other Biomarkers . . 102 Geriatric Neurology Highlights in the Field . . . . . . . . 29   H3 Poster Session VI . . . . . . . . . . . . . . . . . . . 104–111   P6 Frontiers in Neuroscience Plenary Session . . . . 112   S48 Aging, Dementia, and Cognitive and Behavioral Neurology: MRI Imaging . . . . . . . . . . . 114   C122 Traumatic Brain Injury Poster Session VII . . . . . . . . . . . . . . . . . . 118–125   P7   S58 Aging, Dementia, and Cognitive and Behavioral Neurology: Clinical Aspects . . . . . . . . . . 126 34

I  Integrated Neuroscience Session

  C128 Case Studies in Behavioral Neurology:

Focus on Frontotemporal Degeneration

  C137 Mild Cognitive Impairment: Implications for Clinicians   I11

  Proteinopathy in Neurodegenerative Disease . 130

  C147 Dementia Update   C153

  Imaging and Genomics for Detecting Neurodegenerative Proteinopathy in Clinical Practice



Neurology Year in Review Plenary Session . . . . 133

  C155 Cumulative Sports Concussion and Risk of Dementia   C164 Practical Psychopharmacology for Neurologists

Cerebrovascular Disease and Interventional Neurology   C14

Preventing a First Stroke: What Every Neurologist Needs to Know

  C21

Neuro Flash: Acute Stroke Management

  C33

  Prevention of Cardioembolic Stroke in Patients with Nonvalvular Atrial Fibrillation: Recommendations Based on Evidence-based Guidelines and Recent Randomized Trials

  I2

  New Antithrombotic Agents for Stroke Prevention . . . . . . . . . . . . . . . . . . . . . . 43

  C60

Prognostication in the Era of Hypothermia

  C68

Stroke in Childhood and Adolescence

  C80 Stroke In Young Adults   P1

Poster Session I . . . . . . . . . . . . . . . . . . . . 48–55

  P2

Poster Session II . . . . . . . . . . . . . . . . . . . . 56–63

  S3

Section Topic Controversies: PFO: Aggressive Treatment or Just Aspirin . . . . . . . . . . . 65

  S5

Cerebrovascular Disease and Interventional Neurology: Pre-hospital, Telemedicine, and Related Topics . . . . . . 66

  S12

Cerebrovascular Disease and Interventional Neurology: Epidemiology and Risk Factors . . . . . . . . . . . . . . . 67

  P3

Poster Session III . . . . . . . . . . . . . . . . . . . . 70–77

  S15

Cerebrovascular Disease and Interventional Neurology: Clinical and Imaging Biomarkers and Genetics . . . . . . 78

  C103 Therapy of Stroke   P4

Poster Session IV . . . . . . . . . . . . . . . . . . . . 81–88



Contemporary Clinical Issues Plenary Session . . 89

2O14 Scientific Abstract Listing and Annual Meeting Information

  Subspecialty in Focus Track  Leadership Development

  S25   C113   P5   S35   P6

  S45   S51   P7   S55   S62   H13

  C135   C145

  C154

Cerebrovascular Disease and Interventional Neurology: Hemorrhage, Aneurysms, and Vascular Malformations . 90 Acute Stroke Alert Skills Pavilion Poster Session V . . . . . . . . . . . . . . . . . . . .94–101 Cerebrovascular Disease and Interventional Neurology: Issues in Acute Treatment . . . . . . . . . . . . . . . . . 102 Poster Session VI . . . . . . . . . . . . . . . . . . . 104–111 Frontiers in Neuroscience Plenary Session . . . . 112 Cerebrovascular Disease and Interventional Neurology: Rehabilitation, Recovery, and Complications . . . . . . . 114 Cerebrovascular Disease and Interventional Neurology: Large Vessel Atherosclerotic Disease . . . . . . . . . . 115 Poster Session VII . . . . . . . . . . . . . . . . . . 118–125 Pediatric Stroke and Stroke in the Young . . . . . . . . . 126 Cerebrovascular Disease and Interventional Neurology: Cognitive and Behavioral . . . . . . . . . . . . . . . . . 127 Endovascular and Interventional Neurology, and Stroke and Vascular Neurology Highlights in the Field . . 32 Controversies in Neurology Plenary Session . . . 128 Continued Challenges of the Neurohospitalist Model of Care Cerebrovascular Disease Clinical Trials Plenary Session Update on Endovascular Treatment of Cerebrovascular Diseases

Child Neurology and Developmental Neurology   C17   C32   C36

  C49   C68   C80   I4   P1   C91

  P2

  P3   C101   P4   S42

Attention Deficit Hyperactivity Disorder Across the Lifespan Child Neurology I EEG in Children: Developmental Maturation, Variants, Epilepsy Syndromes, and Identification of Surgical Candidates Child Neurology II   Stroke in Childhood and Adolescence Stroke in Young Adults   Recent Advances in Translational Research in Autism . . . . . . . . . . . . . . . . . . . . . 45 Poster Session I . . . . . . . . . . . . . . . . . . . . 48–55 Advances in Autism Spectrum Disorders and Intellectual Disability: From Genetics to Clinical Practice Poster Session II . . . . . . . . . . . . . . . . . . . . 56–63 Presidential Plenary Session . . . . . . . . . . . . . 64 Poster Session III . . . . . . . . . . . . . . . . . . . . 70–77 Neuro Flash: Child Neurology Poster Session IV . . . . . . . . . . . . . . . . . . . . 81–88 Child Neurology I . . . . . . . . . . . . . . . . . . . . . . 103

  Included with registration   Registration fee required

  H1

Child Neurology Highlights in the Field . . . . . . . . . . 29   C119 Syndromes of Autonomic Dysfunction in Children and Adolescents Poster Session VI . . . . . . . . . . . . . . . . . . . 104–111   P6 Poster Session VII . . . . . . . . . . . . . . . . . . 118–125   P7   S60 Child Neurology II . . . . . . . . . . . . . . . . . . . . . . 127   C141 Neurodevelopmental Disabilities Across the Lifespan Epilepsy/Clinical Neurophysiology (EEG)   C2   I1   C36

  C41   S1   C51   C73   P1   C89   P2   C99   P3   P4   S29   P5   S43   H2   P6   S50   C125   P7   S59   C146   C157   C165

How to Analyze Spells by Video-EEG   Temporal Lobe Epilepsy and Febrile Seizures . . 42 EEG in Children: Developmental Maturation, Variants, Epilepsy Syndromes, and Identification of Surgical Candidates Neurophysiologic Intraoperative Monitoring Skills Workshop Section Topic Controversies: ICU EEG Monitoring: Seizures in Critically Ill Patients . . . . . . . . . . . . . . 42   Algorithms in the Diagnosis and Treatment of Epilepsy Clinical EEG Poster Session I . . . . . . . . . . . . . . . . . . . . 48–55 Neuro Flash: Epilepsy Poster Session II . . . . . . . . . . . . . . . . . . . . 56–63 Epilepsy Skills Pavilion Poster Session III . . . . . . . . . . . . . . . . . . . . 70–77 Poster Session IV . . . . . . . . . . . . . . . . . . . . 81–88 Epilepsy and Clinical Neurophysiology:  Inflammation, Status Epilepticus, and Genetics . . . . . 91 Poster Session V . . . . . . . . . . . . . . . . . . . .94–101 Epilepsy and Clinical Neurophysiology (EEG): Cognition . 103 Epilepsy Highlights in the Field . . . . . . . . . . . . . . . 29 Poster Session VI . . . . . . . . . . . . . . . . . . . 104–111 Epilepsy and Clinical Neurophysiology (EEG): Electrophysiology, Imaging, and Functional Connectivity . 115 Status Epilepticus Poster Session VII . . . . . . . . . . . . . . . . . . 118–125 Epilepsy and Clinical Neurophysiology (EEG): Reproduction, Health Care Delivery, and Co-morbidities 127 Clinical Epilepsy Therapy of Epilepsy Critical Care EEG Monitoring

General Neurology   C19

Controversies in Brain Death Determination

  C20 Neuro Flash: MRI and Multiple Sclerosis   C24

Global Health Challenges: Neurology in Developing Countries

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35



Annual Meeting Programs by Topic   C26

Introduction to Genetics

  H13

  C29

Multiple Sclerosis Overview I: Basic and Translational Science

Endovascular and Interventional Neurology, and Stroke and Vascular Neurology Highlights in the Field . . 32

  H14

Women’s Issues in Neurology Highlights in the Field . . . 32

  C34 Neuroimaging for the General Neurologist: Brain



Controversies in Neurology Plenary Session . . . 128

  C37

  C131 Test Your Knowledge:

Therapy in Neurology

A Case-based Approach to Neuroimaging

  C48 Autoimmune Neurology   C52

Neuroimaging for the General Neurologist: Spine and Peripheral Nerve

  C136 Important Drug Interactions for

  C62

Continuum Test Your Knowledge: A Multiple-Choice Question Review

  C144 Neurology Update II

  C69

Improving Accuracy of Dementia Diagnosis: Case Studies with Both Imaging and Neuropathology

  C153 Imaging and Genomics for Detecting Neurodegenerative

Proteinopathy in Clinical Practice

  C161 Neurologic Complications of Medical Disease

  C72

Neurology Update I

  C74

Genetics in Neurology

  C78

Tales from the Front Cover: Effective Book Writing and Publishing for Neurologists

  P1

Poster Session I . . . . . . . . . . . . . . . . . . . . 48–55

  C91

Advances in Autism Spectrum Disorders and Intellectual Disability: From Genetics to Clinical Practice

  C94

Borderlands of Neurology and Internal Medicine

  C9

Differential Diagnosis of Neurologic Infections



Presidential Plenary Session . . . . . . . . . . . . . 64

  C24

  C97

Emergency Neurology

Global Health Challenges: Neurology in Developing Countries

  I5

Revolution of Genetic Tools and the Impact on Neurology . . . . . . . . . . . . . . . . . . 68

  C67

Infections of the Nervous System I: Common Infections

  P3

Poster Session III . . . . . . . . . . . . . . . . . . . . . . 77



Hot Topics Plenary Session . . . . . . . . . . . . . . 80

  P2

Poster Session II . . . . . . . . . . . . . . . . . . . . 56–63

  P4

Poster Session IV . . . . . . . . . . . . . . . . . . . . 81–88

  S10

HIV, PML, and Cerebral Malaria . . . . . . . . . . . . . . 67



Contemporary Clinical Issues Plenary Session . . 89



Hot Topics Plenary Session . . . . . . . . . . . . . . 80

  S31

General Neurology I . . . . . . . . . . . . . . . . . . . . . 91

  P4

Poster Session IV . . . . . . . . . . . . . . . . . . . . 81–88

  I8

Clinical Decision Making After the Dust Settles on Clinical Trials . . . . . . . . . . . . . . . 93

  I10

The Global Burden of Neurological Diseases . . . . . . . 117

  C108 Neurologic Issues in Pregnancy   P5

Poster Session V . . . . . . . . . . . . . . . . . . . .94–101

  S40

General Neurology II . . . . . . . . . . . . . . . . . . . . 103

  C117 Principles of Genomic Medicine:

Whole Exome Sequencing in Neurologic Disease

  C118 Neurotoxicology   C119 Syndromes of Autonomic Dysfunction in

Children and Adolescents

  P6

Poster Session VI . . . . . . . . . . . . . . . . . . . 104–111



Frontiers in Neuroscience Plenary Session . . . . 112

  S52

General Neurology III . . . . . . . . . . . . . . . . . . . . 115

  C121 Office Orthopedics for the Neurologist   C124 Clinical E-Pearls

36

Neurologists and Psychiatrists

  C164 Practical Psychopharmacology for Neurologists   C167 Mitochondrial Disorders in Neurology   C169 Common Neurologic Problems in Adults with Intellectual

and Developmental Disabilities

Global Health and Infectious Disease

  C83 Infections of the Nervous System II: Advanced and

Emerging Infections

  C132 Neuro Flash: Approach to Acute CNS Infections

Headache   C18

Therapy of Headache

  C64

Introduction to Primary Headache Disorders

  C81

Chronic Migraine Education Program

  P1

Poster Session I . . . . . . . . . . . . . . . . . . . . 48–55

  S3

Section Topic Controversies: PFO: Aggressive Treatment or Just Aspirin . . . . . . . . . . . 65

  C100 The Intractable Headache Patient   S32

Headache: Basic Science and Imaging . . . . . . . . . . 91

  P4

Poster Session V . . . . . . . . . . . . . . . . . . . .94–101

  S41

Headache: Clinical . . . . . . . . . . . . . . . . . . . . . 103

  P7

Poster Session VII . . . . . . . . . . . . . . . . . . 118–125

  H5

Headache and Facial Pain Highlights in the Field . . . . . 29

  H12

Adult Intellectual and Developmental Disabilities Highlights in the Field . . . . . . . . . . . . . 32

  P6

Poster Session VI . . . . . . . . . . . . . . . . . . . 104–111

  I9

Emerging Concepts in Headache Therapy . . . . . . . . 116

2O14 Scientific Abstract Listing and Annual Meeting Information

  Subspecialty in Focus Track  Leadership Development

  P7

Poster Session VII . . . . . . . . . . . . . . . . . . 118–125

  C140 Hot Topics in Headaches and Related Disorders



  C158 Psychogenic Movement Disorders   C168 Therapy of Movement Disorders:

A Case-based Approach

Neurology Year in Review Plenary Session . . . . 133

  C159 Challenging Headache Cases

  Included with registration   Registration fee required

MS and CNS Inflammatory Disease

Movement Disorders

  C16

  C12

The Dystonias: Diagnosis, Treatment, and Update on Causes

  C23

Hyperkinetic Movement Disorders: Diagnosis and Treatment

  C28 Botulinum Toxins: Practical Issues and

Clinical Uses for Neurologists

Multiple Sclerosis Essentials

  C20 Neuro Flash: MRI and Multiple Sclerosis   C29

Multiple Sclerosis Overview I: Basic and Translational Science

  C47

Multiple Sclerosis Overview II: Clinical Advances

  C70

Controversies in Multiple Sclerosis Therapy

  P1

Poster Session I . . . . . . . . . . . . . . . . . . . . 48–55

  C44 Update on Ataxias

  C90

Therapy of Multiple Sclerosis

  C53 Clinical Usefulness of Botulinum Toxin and

  P2

Poster Session II . . . . . . . . . . . . . . . . . . . . 56–63

  S4

MS and CNS Inflammatory Disease: Clinical Trials . . . . 66

  S13

MS and CNS Inflammatory Disease: MRI Atrophy Measures and Correlations . . . . . . . . . 67

Treatment of Dystonia Skills Pavilion

  C58 Hallucinations in Parkinson’s Disease   C71

Movement Disorders

  P1

Poster Session I . . . . . . . . . . . . . . . . . . . . 48–55

  P3

Poster Session III . . . . . . . . . . . . . . . . . . . . 70–77

  P2

Poster Session II . . . . . . . . . . . . . . . . . . . . 56–63

  S14

  S7

Parkinson’s Disease: Preclinical and Clinical Therapeutics . . . . . . . . . . . . . . . . . . . . 66

MS and CNS Inflammatory Disease: Animal and In Vitro Studies . . . . . . . . . . . . . . . . . . . . . 78

  S23

  C95

Deep Brain Stimulation Management

MS and CNS Inflammatory Disease: Novel Therapeutics . . . . . . . . . . . . . . . . . . . . . 79

  P3

Poster Session III . . . . . . . . . . . . . . . . . . . . 70–77

  S17

Parkinson’s Disease: Genetics and Epidemiology . . . . . 78



Hot Topics Plenary Session . . . . . . . . . . . . . . 80

  C101 Neuro Flash: Child Neurology   C102 Balance and Gait Disorders

  C106 Integrative Management of MS   P4

Poster Session IV . . . . . . . . . . . . . . . . . . . . 81–88

  S24

Diet and Hormonal Influences in MS . . . . . . . . . . . 90

  S33

Cognition Fatigue in MS . . . . . . . . . . . . . . . . . . 91

  I7

Emerging Therapeutic Advances in Multiple Sclerosis . . 92

  P5

Poster Session V . . . . . . . . . . . . . . . . . . . .94–101

  S34

MS and CNS Inflammatory Disease: Risk Factors for MS Disease and Course102 Multiple Sclerosis Highlights in the Field . . . . . . . . . 29

  P4

Poster Session IV . . . . . . . . . . . . . . . . . . . . 81–88



Contemporary Clinical Issues Plenary Session . . 89

  S27

Dystonia, Tremor, and Other Movement Disorders . . . . 90

  H6

  P5

Poster Session V . . . . . . . . . . . . . . . . . . . .94–101

  C114 Morning Report: Multiple Sclerosis

  S37

Clinical Aspects of Parkinson’s Disease . . . . . . . . . 102

  P6

Poster Session VI . . . . . . . . . . . . . . . . . . . 104–111

  H5

Movement Disorders Highlights in the Field . . . . . . . 29

  S44

MS and CNS Inflammatory Disease: Neuroimaging I . . 114

  C116 Learning Movement Disorders in Hindsight:

  S53

MS and CNS Inflammatory Disease: Biomarkers and Therapeutic Mechanisms . . . . . . . . 115

  P6

Poster Session VI . . . . . . . . . . . . . . . . . . . 104–111

  P7

Poster Session VII . . . . . . . . . . . . . . . . . . 118–125

  S47

Movement Disorders: Huntington’s Disease, Ataxia, and Wilson’s Disease . . . . . . . . . . . . . . . 114

  S54

MS and CNS Inflammatory Disease: Neuroimaging II . . 126

  S63

Neuromyelitis Optica and Autoimmune Encephalitis . . 127

  P7

Poster Session VII . . . . . . . . . . . . . . . . . . 118–125



Controversies in Neurology Plenary Session . . . 128

  S57

Movement Disorders: Imaging . . . . . . . . . . . . . . 126

  C129 Case Studies: Multiple Sclerosis

Lessons from My Patients

  C127 Case Studies: Unusual Movement Disorders

  C139 Neuromyelitis Optica: Scientific and Clinical Update

  C134 Parkinson’s Disease Management: Pearls, Pitfalls, and



Future Prospects

  C138 Parkinson’s Disease and Movement Disorders Update



Clinical Trials Plenary Session . . . . . . . . . . . . 131

  C152 Symptomatic Management in Multiple Sclerosis

Neurology Year in Review Plenary Session . . . . 133



Neurology Year in Review Plenary Session . . . . 133

  C162 Diagnostic Dilemmas in Multiple Sclerosis

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37



Annual Meeting Programs by Topic Neuro Trauma, Critical Care, and Sports Neurology   C38 Neurologic Intensive Care   S1

Section Topic Controversies:  ICU EEG Monitoring: Seizures in Critically Ill Patients . . 42

  P4   S26   C112   P5

  C82 Sports Neurology: Non-Concussion Overview

  S36

  S3

Section Topic Controversies: PFO: Aggressive Treatment or Just Aspirin . . . . . . . . 65

  P6

  S11

Neuro Trauma, Critical Care, and Sports Neurology . . . 67

  C97

Emergency Neurology

  P7



Hot Topics Plenary Session . . . . . . . . . . . . . . 80

  S56

  S46

  C101 Neuro Flash: Child Neurology

  S61

  C109 Emergency Room Neuro-ophthalmology

  C126

  C110 Sports Concussion and Other Mild Concussive Injuries   P5

Poster Session V . . . . . . . . . . . . . . . . . . . .94–101

  H15

Critical Care Highlights in the Field . . . . . . . . . . . . 29

  H11

Sports Neurology Highlights in the Field . . . . . . . . . 29

  C120 Consultations in the Medical Surgical ICU   C121 Office Orthopedics for the Neurologist   C122 Traumatic Brain Injury   C142   S64

  Concussion in the Military and in Sports Section Topic Controversies: Pain: Methods of Treatment . . . . . . . . . . . . . . . . 132

  I12

  Concussion in Sports and the Military . . . . . 132 Neurology Year in Review Plenary Session . . . . 133

 

  C155 Cumulative Sports Concussion and Risk of Dementia   C165 Critical Care EEG Monitoring

Neuromuscular and Clinical Neurophysiology (EMG)   C1

Clinical Approach to Muscle Disease

  C8

Evaluation and Management of Autonomic Disorders

  C22 You Make the Call—An Interactive, Multimedia,

Case-based Approach to Learning EMG

  C27

Clinical EMG I

  C45 Clinical EMG II   C57

Small Fiber Neuropathies: Sensory, Autonomic and Both

  C76

EMG Skills Workshop: Basic

S2 Cancelled      P1

Poster Session I . . . . . . . . . . . . . . . . . . . . 48–55

  C93

Therapy of Neuromuscular Disease

  P2

Poster Session II . . . . . . . . . . . . . . . . . . . . 56–63

  S6

Neuromuscular Disease: Gene Therapy I . . . . . . . . . 66

  I6

Peripheral Neuropathies . . . . . . . . . . . . . . . . . . 69

  P3

Poster Session III . . . . . . . . . . . . . . . . . . . . 70–77

  S16

Neuromuscular and Clinical Neurophysiology (EMG): Clinical Trials and Therapy . . . . . . . . . . . . . . . . . 78

38

  C133   C143   C148

  C160

Poster Session IV . . . . . . . . . . . . . . . . . . . . 81–88 Biomarkers in Neuromuscular Diseases . . . . . . . . . . 90 Neuromuscular Bedside Rounds Skills Pavilion Poster Session V . . . . . . . . . . . . . . . . . . . .94–101 Neuromuscular Disease: Clinical . . . . . . . . . . . . . 102 Poster Session VI . . . . . . . . . . . . . . . . . . . 104–111 Neuromuscular Disease: Genetics, Pathogenesis, and Measures . . . . . . . . . . . . . . . 114 Poster Session VII . . . . . . . . . . . . . . . . . . 118–125 Anterior Horn Disease . . . . . . . . . . . . . . . . . . . 126 Muscle Disease: Gene Therapy and Models . . . . . . . 127 Case Studies: Unusual Diagnostic and Management of Cases in Neuromuscular Disease The Spectrum of Motor Neuron Disease Peripheral Neuropathy Neuromuscular Ultrasound Skills Workshop Neurology Year in Review Plenary Session . . . . 133 Neuromuscular Junction Disorders

Neuro-oncology   C65

Neurologic Complications of Systemic Cancer Poster Session III . . . . . . . . . . . . . . . . . . . . 70–77   P3   S22 Neuro-oncology . . . . . . . . . . . . . . . . . . . . . . 79 Neuro-oncology Highlights in the Field . . . . . . . . . . 29   H8 Poster Session VII . . . . . . . . . . . . . . . . . . 118–125   P7   C130 Case Studies: Neurologic Consultations in Cancer Patients Clinical Trials Plenary Session . . . . . . . . . . . . 131   C150 Neuro-oncology: Primary Brain Tumors Neuro-ophthalmology/Neuro-otology   C15

Top 10 Neuro-ophthalmic Diagnoses You Can’t Afford to Miss   C39 Neuro-ophthalmology   C56 Neuro Flash: Neuro-ophthalmology S2 Cancelled      C87 Eye Movement Disorders: A Systematic Approach to the Evaluation of Diplopia Poster Session II . . . . . . . . . . . . . . . . . . . . 56–63   P2 S19 Neuro-ophthalmology/Neuro-otology I . . . . . . . . . . 79      C104 Nystagmus: An Organized Approach   C109 Emergency Room Neuro-ophthalmology   S39 Neuro-ophthalmology/Neuro-otology II . . . . . . . . . 103   H9 Neuro-ophthalmology/Neuro-otology Highlights in the Field . . . . . . . . . . . . . . . . . . . . 29 Poster Session VI . . . . . . . . . . . . . . . . . . . 104–111   P6

2O14 Scientific Abstract Listing and Annual Meeting Information

  Subspecialty in Focus Track  Leadership Development

  Included with registration   Registration fee required

  C123 Neuro-ophthalmology and Neurovestibular Exam Lab Skills

  C61

Resident and Fellow Career Breakfast: The Early Years

Clinical Trials Plenary Session . . . . . . . . . . . . 131

  C66

Teleneurology and Technologies

  C75

 Women in Leadership Philanthropy 101

Pavilion



  C149 Neuro-otology

  C77

Neuro-rehabilitation

  C85

  C40 Spine Neurology: Assessment and Management of

Common Spine Disorders

  C54 Morning Report: Lumbar Radiculopathy,

 Improving Your Leadership Skills: A Practical Approach

  CQ8 Health Information Technology Colloquium:

Advancements in Technology

Lumbar Spinal Stenosis, Low Back Pain, and Post-Laminectomy Syndrome

  C86

ICD 10-CM: Essentials of Understanding and Implementation

  P1

Poster Session I . . . . . . . . . . . . . . . . . . . . 48–55



Presidential Plenary Session . . . . . . . . . . . . . 64

  S21

Neurorehabilitation and Neural Repair . . . . . . . . . . 79

  C98

Practical Legal Issues for Neurologists

  P4

Poster Session IV . . . . . . . . . . . . . . . . . . . . 81–88

  C107 Brain Computer Interfaces: Frontiers in

Neurology and Neuroscience

  C111 Bedside Evidence-based Medicine:

  H7

Neural Repair and Rehabilitation Highlights in the Field . 29



Frontiers in Neuroscience Plenary Session . . . . 112

  C122 Traumatic Brain Injury

How to Deconstruct Articles in Order to Take Care of Patients

  C115 Neuro Flash: Palliative Care for the

Practicing Neurologist

  C163 Myelopathies

  S49

  C135 Continued Challenges of the

Pain and Palliative Care

Neurohospitalist Model of Care

  C40 Spine Neurology: Assessment and Management of

Common Spine Disorders

Research Methodology, Education, and History

  C50 Core Concepts in Pain Management   C54 Morning Report: Lumbar Radiculopathy,

Lumbar Spinal Stenosis, Low Back Pain, and Post-Laminectomy Syndrome

  S20

Pain and Palliative Care . . . . . . . . . . . . . . . . . . . 79

  P7

Poster Session VII . . . . . . . . . . . . . . . . . . 118–125

  C115 Neuro Flash: Palliative Care for the

Practicing Neurologist

  S64

Practice, Policy, and Ethics . . . . . . . . . . . . . . . . . 115

Section Topic Controversies: Pain: Methods of Treatment . . . . . . . . . . . . . . . . . . . 132

  C4

Resident Basic Science I: Neuropathology

  C7

Research Career Development Symposium: How to Be Successful in Academic Neuroscience

  C11

Resident Basic Science II: Neuroanatomy

  CQ2 Research and Technology Colloquium:

From Discovery to Therapy

  C31   C35

 Life Reimagined   CQ4 Clinical Research Colloquium

  C59

Practice, Policy, and Ethics

Resident Basic Science III: Neuropharmacology

Career Development for Clinician Educators

  CQ6 Education Colloquium

  C5

Clerkship and Program Directors Conference

  C75

 Women in Leadership   C77 Philanthropy 101

  C6

The Practice of Neurology:  Issues in Coding and Reimbursement

  C78

Tales from the Front Cover: Effective Book Writing and Publishing for Neurologists

and Improving Your Bottom Line

  C79

Strategic Grant Writing

  C13

Practice Survival for Neurologists: Business Strategies for Success



Futures in Clinical Research Luncheon (Registration Required) . . . . . . . . . . . . . . . . . . . 23

  C19

Controversies in Brain Death Determination

  C85

 Improving Your Leadership Skills: A Practical Approach

  CQ1 BRAINS Colloquium: Understanding

  CQ3 Patient Safety Colloquium   C43 E/M: Minimize Mistakes, Maximize Reimbursement   CQ5 Practice Colloquium: How to Navigate and

Succeed in New Payment Models

  CQ7 Education Research Colloquium   P1

Poster Session I . . . . . . . . . . . . . . . . . . . . 48–55

  C88 Hot Topics in Education (Tentative)

Fast, Easy Registration Online  ·  AAN.com/view/AM14

39



Programs by Topic

Futures in Clinical Research Luncheon Mentoring Sessions (Registration Required) .   C96 The History of Certain Disorders of the Nervous System Revolution of Genetic Tools and   I5 the Impact on Neurology . . . . . . . . . . . . . . . . . .   S30 Education, Research, and History . . . . . . . . . . . . . Clinical Decision Making After the   I8 Dust Settles on Clinical Trials . . . . . . . . . . . . . . .

  Subspecialty in Focus Track  Leadership Development

23

68 91 93

Sleep   C10

Approach to Sleep Symptoms: Sleepy or Sleepless   C30 Sleep for the Practicing Neurologist   Clocks, Sleep, Brain Health and Disorders:   I3  Impact on Mechanism, Expression, and Treatment . . . 44   Sleep Principles Applied to   C84 Neurological Disease   S9 Sleep . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67 Contemporary Clinical Issues Plenary Session . . 89 Poster Session V . . . . . . . . . . . . . . . . . . . .94–101   P5   H10 Sleep Highlights in the Field . . . . . . . . . . . . . . . . 29   S64 Section Topic Controversies: Pain: Methods of Treatment . . . . . . . . . . . . . . . . . . . 132   C151 Hot Topics in Sleep Neurology   C156 Evaluation and Therapy of Restless Legs Syndrome and Periodic Limb Movements in Sleep   C166 Interpretation of Polysomnography for the Practicing Neurologist

“[At the Education Programs] I like to hear what other people are doing, even if it only confirms that we are doing the up-to-the-date thing. I learn some new ideas, things that have worked, things that haven’t worked. The best part is that [the AAN has] put everything on the web or app, which is new. Major improvement.” David Kauffman, MD Scarsdale, NY

40

  Included with registration   Registration fee required

2O14 Scientific Abstract Listing and Annual Meeting Information



Sunday, April 27 Temporal Lobe Epilepsy and Febrile Seizures

I1 

8:00 a.m.–12:00 p.m.

Coordinators: Shlomo Shinnar, MD, PhD, FAAN and Tallie Z. Baram, MD, PhD Invited Speaker Session:  8:00 a.m.–10:30 a.m. 8:00 a.m.–8:45 a.m.

Epidemiological Aspects of Febrile Seizures, Febrile Status Epilepticus and Temporal Lobe Epilepsy  Dale C. Hesdorffer, PhD

8:45 a.m.–9:30 a.m.

What Are the Causal Relationships of Febrile Seizures / FSE and Temporal Lobe Epilepsy? Challenges and Emerging Answers  Tallie Z. Baram, MD, PhD

9:30 a.m.–10:15 a.m. Febrile Status Epilepticus and Temporal Lobe Epilepsy: Insights from a Multi-Center Prospective Study  Shlomo Shinnar, MD, PhD, FAAN 10:15 a.m.–10:30 a.m. Questions and Answers

Poster Rounds:  10:30 a.m.–11:30 a.m. I1-1.001

Sequential Versus Simultaneous Polytherapy in the Treatment of Status Epilepticus  Claude Wasterlain, Roger Baldwin, Jerome Niquet, Lucie Suchomelova

I1-1.002 Mismatch of Structural and

Functional Reorganization In Language Network asSCX Left Temporal Lobe Epilepsy Shigetoshi Takaya, Naoaki Tanaka, Hesheng Liu, Douglas Greve, Claus Reinsberger, Andrew Cole, Emad Eskandar, Steven Stufflebeam

I1-1.003 Influences of Temporal Lobe

Epilepsy and Temporal Lobe Resection on Olfactory Function  Richard Doty, Isabelle Tourbier, Taehoon Kim, Jonathan Silas, Paul Moberg, Ashwini Sharan, Michael Sperling, Bruce Turetsky

I1-1.004 Physiologic and Cortical

Response to Acute Psychosocial Stress in Left Temporal Lobe Epilepsy Jane Allendorfer, Heidi Heyse, Lucy Mendoza, Jerzy Szaflarski

I1-1.005 Graph Theory Based

Functional Connectivity in Lateralized Temporal Lobe Epilepsy  Sharon Chiang, John Stern, Jerome Engel, Harvey Levin, Zulfi Haneef

I1-1.006

Factors Independently Associated with Anxiety and Depression in Epilepsy  Heidi Munger Clary, Marla Hamberger

I1-1.007

Efficacy of Transcranial Direct Current Stimulation on Working Memory and Mood in Patients with Temporal Lobe Epilepsy  Anli Liu, Orrin Devinsky, Andrew Bryant, Ashlie Jefferson, Daniel Friedman, Mouhsin Shafi, William Barr, Daniel Press, Susan Herman, Margaret O’Connor, Steven Schachter, Alvaro PascualLeone

I1-1.008 Utility of CT Perfusion

(CTP) Imaging in Seizures: A Retrospective Analysis and Literature Review Aunali Khaku, Vishunmurthy Hedna, Michael Waters

I1-1.009

Serum IL6, IL1β and IL1Ra Levels in Patients With Epilepsy Irem Fatma Uludag, Tarik Duksal, Yasar Zorlu, Feriha Ozkaya, Guldal Kirkali

I1-1.010

Is Presurgical MEG Useful in Intractable Temporal Lobe Epilepsy? Helen Barkan, Shannon Sparrow, Ann Marie Collier, Michael Funke

Data Blitz:  11:30 a.m.–12:00 p.m. 11:30 a.m.

I1-2.001

11:35 a.m.

I1-2.002

The Role of Toll-Like Receptor 3 in Epileptogenesis  Felix Benninger, Adi Gross, Israel Steiner, Daniel Offen, Eitan Okun

Human Mesial Temporal Lobe Single Neuron Dynamics During Recruitment Into a Generalizing Seizure  Amrit Misra, Xianda Long, Ashwini Sharan, Michael Sperling, Karen Moxon

11:40 a.m.

I1-2.003

Association Between Human Herpes Virus 6 and Hippocampal Volume in Mesial Temporal Lobe Epilepsy  William Theodore, Emily Leibovitch, Bridgette Billioux, Sierra Germeyan, David Kalikhman, Sara Inati, John Heiss, Kareem Zaghloul, Steven Jacobson

11:45 a.m.

I1-2.004

Virtual Car Accident Rates of Epilepsy Patients are Significantly Increased by Interictal Generalized Spike Waves  Heinz Krestel, Andreas von Allmen, Christian Liechti, Maja Steinlin, Johannes Mathis, Nirkko Arto

S1 Section Topic Controversies: I CU EEG Monitoring: Seizures in Critically Ill Patients

11:50 a.m.

I1-2.005

Correlation Between MRI Findings of Mesial Temporal Sclerosis and Histopathological Findings  Judy Li, Steve Chung

1:00 p.m.–2:30 p.m.

1:00 p.m.–1:05 p.m. Introduction:  Kimford J. Meador, MD, FAAN

42

1:05 p.m.–1:45 p.m.

Debate: Most Critically Ill Patients Should Undergo Continuous EEG Monitoring Pro:  Lawrence J. Hirsch, MD, FAAN Con:  Frank W. Drislane, MD, FAAN

1:45 p.m.–2:25 p.m.

Debate: All Seizures in Critically Ill Patients Should Be Aggressively Treated and Stopped As Soon As Possible Pro:  Stephan A. Mayer, MD Con:  Peter W. Kaplan, MBBS, FRCP, FAAN

2:25 p.m.–2:30 p.m.

Concluding Remarks:  Kimford J. Meador, MD, FAAN

2O14 Scientific Abstract Listing and Annual Meeting Information

Integrated Neuroscience Sessions/Section Topic Controversies  New Antithrombotic Agents for Stroke Prevention

1:00 p.m.–5:00 p.m. Sunday April 27

I2 

Coordinators: Seemant Chaturvedi, MD, FAAN, FAHA and Antonio Culebras, MD, FAAN, FAHA Invited Speaker Session:  1:00 p.m.–3:30 p.m. 1:00 p.m.–1:10 p.m. Introduction  Antonio Culebras, MD, FAAN, FAHA 1:10 p.m.–1:40 p.m.

The “New” Oral Anticoagulants for Stroke Prevention  Cathy A. Sila, MD, FAAN

1:40 p.m.–2:10 p.m.

Periprocedural Management of Antithrombotic Therapy  Jose Biller, MD, FAAN, FACP, FAHA

2:10 p.m.–2:20 p.m. Break 2:20 p.m.–2:50 p.m.

Management of Bleeding Complications  Julius Latorre, MD

2:50 p.m.–3:15 p.m.

Potential Futures Uses of Novel Oral Anticoagulants  Mukul Sharma, MD

3:15 p.m.–3:30 p.m. Discussion

Poster Rounds:  3:30 p.m.–4:30 p.m. I2-1.001 Effect of Apixaban on

All-Cause Mortality in Atrial Fibrillation: An Imputed Placebo Analysis John McMurray, Robert Hart, Greg Flaker, Renato Lopes, Junyuan Wang, Michael Hanna, John Alexander, Christopher Granger, Lars Wallentin

I2-1.002 Risk of Bleeding from

Antithrombotic Agents (AT) in Patients with Cerebral Cavernous Malformations (CCMs).  Robert Wityk

I2-1.003 Diagnostic Yield of

I2-1.006 The Incidence of Secondary

I2-1.004 Stroke in Very Old

I2-1.007 Neuroanatomical Correlates

Prolonged Cardiac Rhythm Monitoring in Cryptogenic Stroke  Rizwan Kalani, Richard Bernstein, Yvonne Curran, Ilana Ruff, Shyam Prabhakaran Patients  Drini Dobi, Mira Kapisyzi, Jera Kruja

I2-1.005 Cryptogenic Stroke with

No Cause Demonstrates the Outcome Prediction Utility of TOAST Classifications in a Large Stroke Patient Sample Tyler Scullen, Dominique Monlezun, Jr, Alexander George, James Siegler, Melissa Schwickrath, Ramy El Khoury, Sheryl Martin-Schild

Stroke Prevention Medication Following Hospitalization for Ischemic Stroke Justin Blackburn, Hong Zhao, Meredith Kilgore, Karen Albright

of Atrial Fibrillation: A Longitudinal MRI Study  Aveen Saed, Nudrat Tasneem, Malik Adil, Mushtaq Qureshi, Adnan Qureshi

I2-1.009 Warfarin Associated

Intracerebral Hemorrhage in Hong Kong Chinese  Kay Cheong Teo, Neeraj R Mahboobani, Raymand Lee, David CW Siu, Raymond Cheung, Shu Leong Ho, Gary KK Lau, Koon Ho Chan

I2-1.010

Stroke Patients and Diagnostic Testing—the Weekend Waiting Game!  Sally Mathias, Jessica Lee

I2-1.008 Etiologies of Intracerebral Hemorrhages from 2009-2012 at Mayo Clinic-Rochester  James Klaas, Sherri Braksick, Robert Brown, Alejandro Rabinstein, Jennifer Fugate

Data Blitz:  4:30 p.m.–5:00 p.m. 4:30 p.m.

I2-2.001

Oral Anticoagulant Therapy Is Associated with Cerebral Microbleeds  Saloua Akoudad, Sirwan Darweesh, Maarten Leening, Peter Koudstaal, Albert Hofman, Aad Van Der Lugt, Bruno Stricker, Mohammad Ikram, Meike Vernooij

4:35 p.m.

I2-2.002

Mobile Cardiac Outpatient Telemetry Identifies Occult Atrial Fibrillation After Cryptogenic Stroke  Erin Ingala, Jenny Jara, Emily Fessler, Brett Cucchiara, Steven Messe, Michael Mullen, Allyson Prasad, Mathew Hutchinson, Scott Kasner



4:40 p.m.

I2-2.003

Use of Apixaban and Warfarin in Patients Undergoing Procedures: Insights from ARISTOTLE  Renato Lopes, David Garcia, Daniel Wojdyla, Paul Dorian, John Alexander, Lars Wallentin, Fernando Lanas, Michael Hanna, Claes Held, Christopher Granger

4:45 p.m.

I2-2.004

4:50 p.m.

I2-2.005

Infarction Volume in Patients with Atrial Fibrillation: The Impact of Left Ventricular Stiffness  Hee-Seung Ahn, Wi-Sun Ryu Direct Thrombin Inhibitors May Have a Decreased Risk of Intracerebral Hemorrhage Compared with Older Anticoagulants  Sindhu Ravipati, Daniel Woo, Padmini Sekar, Charles Moomaw, Matthew Flaherty, Jennifer Osborne

Fast, Easy Registration Online  ·  AAN.com/view/AM14

43



Monday, April 28 I3   Clocks, Sleep, Brain Health and Disorders: Impact on Mechanism, Expression, and Treatment

8:00 a.m.–12:00 p.m.

Coordinators: Bradley V. Vaughn, MD, FAAN and Phyllis C. Zee, MD, PhD Invited Speaker Session:  8:00 a.m.–10:30 a.m. 8:00 a.m.–8:10 a.m. Introduction  Phyllis C. Zee, MD, PhD 8:10 a.m.–8:40 a.m.

Neurobiology of Sleep and Wake Regulation  Clifford B. Saper, MD, PhD, FAAN

8:40 a.m.–9:10 a.m.

The Role of Circadian Rhythm Dysfunction in Huntington Disease  A. Jennifer Morton

9:10 a.m.–9:45 a.m.

Bi-directional Relationship Between Sleep, Circadian Rhythms, and Neurodegeneration  David M. Holtzman, MD, FAAN

9:45 a.m.–10:15 a.m. Circadian Rhythm and Sleep in Epilepsy  Mark S. Quigg, MD 10:15 a.m.–10:30 a.m. Questions and Answers

Poster Rounds:  10:30 a.m.–11:30 a.m. I3-1.001 A Novel Capability for

I3-1.003 Diffusion Tensor Imaging

I3-1.002 Poor Sleep and White

I3-1.004 Investigating the Night to

Monitoring Cerebral and Systemic Hemodynamics, ECG and Actigraphy During Sleep  Vladimir Ivkovic, Gary Strangman, Quan Zhang Matter Quality Among Middle Aged Adults  Kristine Yaffe, Jasmine Nettiksimmons, Lenore Launer, Stephen Sidney, Mercedes Carnethon, Kristine Knutson, Diane Lauderdale, Cora Lewis, Nick Bryan

as a Biomarker for REM Sleep Behavior Disorder and Parkinson’s Disease Matthew Brodsky, John Grinstead, David Lahna, Jeffrey Pollock Night Variability of REM Without Atonia in Parkinson’s Disease  Samuel Bolitho, Sharon Naismith, Ron Grunstein, Zoe Terpening, Moran Gilat, Simon Lewis

I3-1.005 Multiple Sclerosis Reported Fatigue: Obstructive Sleep Apnea and Abnormalities in Sleep Architecture in a Community Cohort  Mark Gudesblatt, Myassar Zarif, Barbara Bumstead, Lori Fafard, Marijean Buhse, Steven Brass, Konstantina Bardhi, Steven Xian

I3-1.006 Diazepam Useful in ESES Treatment  Mirret El-Hagrassy, Chulaka Gunasekara, Yaman Eksioglu

I3-1.007 Sleep Abnormalities in

Children with Dravet Syndrome Radhika Dhamija, Maia Erickson, Erik St Louis, Suresh Kotagal

I3-1.008 Nocturnal Melatonin

Regulation in Post-Traumatic Vegetative State: A Possible Role for Melatonin Supplementation?  Pietro Guaraldi, Elisa Sancisi, Giovanna Calandra-Buonaura, Chiara La Morgia, Valerio Carelli, Cameli Olivia, Alberto Battistini, Pietro Cortelli, Roberto Piperno

I3-1.009 The Efficacy of Gabapentin

Enacarbil (GEn) in Adult Patients with Severe Primary Restless Legs Syndrome (RLS): Pooled Analyses from 3 Randomized Trials  Daniel Lee, William Ondo, Alon Avidan, Diego García-Borreguero, Mark Jaros, Richard Kim, Gwendoline Shang

Data Blitz:  11:30 a.m.–12:00 p.m. 11:30 a.m.

I3-2.001

Distinct Innervation Patterns of the Melanin Concentrating Hormone Neurons from the Basal Forebrain Structures  Minjee Kim, Lindsay Agosstinelli, Thomas Scammell

11:35 a.m.

I3-2.002

Comparing Periodic Limb Movements in Sleep in Subjects with and without Waking Paretic/Plegic Limbs  Mark Dyken, Miriam Zimmerman, Kyoungbin Im, Deborah Lin-Dyken, Christine Glenn, Mark Blumberg, Robert Rodnitzky, Greta Sokoloff

11:40 a.m.

I3-2.003

11:45 a.m.

I3-2.004

Exploring The Neural Circuitry of REM Sleep Behavior Disorder In Parkinson’s Disease Using Functional MRI  Samuel Bolitho, James Shine, Sharon Naismith, Ron Grunstein, Peter Bell, Simon Lewis

Bright Light Therapy Improves Excessive Daytime Sleepiness Associated with Parkinson’s Disease  Aleksandar Videnovic, Angelica Marconi, Teresa Kuhta, Scott Miskevics, Phyllis Zee

S2  Cancelled

44

2O14 Scientific Abstract Listing and Annual Meeting Information

11:50 a.m.

I3-2.005

Antibodies Against the Cell Adhesion Molecule Iglon5 Identify a Novel Tauopathy with NREM/REM Parasomnia and Sleep Breathing Disorder  Carles Gaig, Lidia Sabater, Ellen Gelpi, Luis Bataller, Jan Lewerenz, Estefania Torres-Vega, Angeles Contreras, Bruno Giometto, Yaroslau Compta, Cristina Embid, Isabel Vilaseca, Alex Iranzo, Joan Santamaria, Josep Dalmau, Francesc Graus

1:00 p.m.–2:30 p.m.

Integrated Neuroscience Sessions/Section Topic Controversies I4   Recent Advances in Translational Research in Autism

1:00 p.m.–5:00 p.m.

Coordinators: Margaret L. Bauman, MD, FAAN and Martha R. Herbert, MD, PhD Invited Speaker Session:  1:00 p.m.–3:30 p.m. 1:00 p.m.–1:10 p.m. Introduction Autism Spectrum and Epilepsy Spectrum  Frances E. Jensen, MD

1:40 p.m.–2:10 p.m.

GI and Autism from Research and Clinical Point of View  Kara Gross, MD

2:10 p.m.–2:40 p.m.

Autism, GI, MET Genes, and Connectivity Theory  Pat Levitt, PhD

2:40 p.m.–3:10 p.m.

Mitochondrial Dysfunction, Purinergic Signaling, ASD, and Clinical Trials  Robert Naviaux, MD, PhD

3:10 p.m.–3:30 p.m.

Questions and Answers

Monday April 28

1:10 p.m.–1:40 p.m.

Poster Rounds:  3:30 p.m.–4:30 p.m. I4-1.001 SHANK3 Overexpression

Causes Manic-like Behavior with Unique Pharmacogenetic Properties Jimmy Holder, Huda Zoghbi

I4-1.002 Predictors of Response to

I4-1.004 Knockout of p75NTR in

Cerebellar Purkinje Cells Results in an Autism-like Murine Phenotype Nina Schor, Deborah Cory-Slechta, Louis Lotta, Katherine Conrad

Propranolol for Social Functioning in Autism Spectrum Disorder  David Beversdorf, Rachel Zamzow, Brad Ferguson, Tamera Martin, Morgan Lewis, Janine Stichter

I4-1.005 Resting State EEG Serves

I4-1.003 Cognitive and

I4-1.006 Behavioral Profiles of

Developmental Predictors of ASD in Infants with Tuberous Sclerosis Complex. Shafali Jeste, Joyce Wu, Damla Senturak, Mustafa Sahin, Charles Nelson

as a Promising Biomarker of Cognitive and Language Function in Young Children with ASD.  Kevin McEvoy, Shafali Jeste Children and Adolescents with Specific Language Impairment and High Functioning Autism  Marisela Dy, Angela Ballantyne, Doris Trauner

I4-1.007 Mean EEG Coherence

in Infants at Risk for Autism Spectrum Disorder  April Levin, Marc Shi, Helen Tager-Flusberg, Charles Nelson

I4-1.008 Genetic Animal Models

I4-1.010

Intrinsic Excitability Defects in Specific Subtypes of Medial Prefrontal Cortex Pyramidal Neurons in a Mouse Model of Autism  Audrey Brumback, Vikaas Sohal

of Autism Based on Shank/ Mutation Molecules to Potential Therapeutics Craig Powell

I4-1.009 Autistic Symptoms in a

Geriatric Population with Mild Cognitive Impairment and Early Dementia Danielle Crawford, Erin Abner, Paul Glaser, Gregory Jicha

Data Blitz:  4:30 p.m.–5:00 p.m. 4:30 p.m.

I4-2.001

Abnormal White Matter Connectivity in Children with Autism or Sensory Processing Disorder: Overlap and Divergence.  Elysa Marco, YiShin Chang, Julia Owen, Shivani Desai, Julia Harris, Susanna Hill, Anne Arnette, Pratik Mukherjee

4:35 p.m.

I4-2.002

4:40 p.m.

I4-2.003

Delayed Low Level Visual Processing in Infants with Tuberous Sclerosis Complex (TSC)  Pilar Pichon, Jordan Ko, Charles Nelson III, Shafali Jeste Value of Routine EEG in Autistic Patients with Stereotypic Behavioral Movements  Ankit Nayyar, Neha Mirchandani, Rebecca Spiegel

4:45 p.m.

I4-2.004

High-Functioning Autistic Children Have Abnormal Stapedial Reflexes  Richard Lukose, Randy Kulesza, Kevin Brown, Barber Carol

4:50 p.m.

I4-2.005

Reduction in Retinal Nerve Fiber Layer Thickness in Young Adults with Autism Spectrum Disorders  Matteo Pardini, Leonardo Emberti Gialloreti, Francesca Benassi, Sara Marciano, Mario Amore, Maria Giulia Mutolo, Maria Cristina Porfirio, Paolo Curatolo

“[The Annual Meeting is] so exciting because you see the faces of the people whose papers you have read. People are usually accessible and you can network with them.” Salvatore Di Mauro, MD New York, NY



Fast, Easy Registration Online  ·  AAN.com/view/AM14 45

Introducing ePosters! The new ePoster session will take place in the poster hall, April 28 through May 1 and will feature digital presentations of select scientific posters. This new format will allow authors to feature compelling visual components, such as: ¡ Images ¡ Video ¡ 3D Models For location of the ePoster session, see the poster session floor plan on the next page.

April 26 – May 3, 2014 Philadelphia, PA

Poster Session Floor Plan Poster Session Schedule Monday, April 28 P1  Poster Session I

3:00 p.m.–6:30 p.m. 5:00 p.m.–6:30 p.m.*

ePosters

Tuesday, April 29

015 014 013 012 011

P2  Poster Session II

7:30 a.m.–11:00 a.m. 7:30 a.m.–9:00 a.m.*

016 017 018 019 020

P3  Poster Session III

3:00 p.m.–6:30 p.m. 5:00 p.m.–6:30 p.m.*

Wednesday, April 30 P4  Poster Session IV

7:30 a.m.–11:00 a.m. 7:30 a.m.–9:00 a.m.* P5  Poster Session V

3:00 p.m.–6:30 p.m. 5:00 p.m.–6:30 p.m.*

Thursday, May 1 P6  Poster Session VI

7:30 a.m.–11:00 a.m. 7:30 a.m.–9:00 a.m.* P7  Poster Session VII

3:00 p.m.–6:30 p.m. 5:00 p.m.–6:30 p.m.*

021 022 023 024 025 026 027 028 029 030

060 059 058 057 056 055 054 053 052 051

061 062 063 064 065 066 067 068 069

118 117 116 115 114 113 112 111 110

119 120 121 122 123 124 125 126 127

176 175 174 173 172 171 170 169 168

177 178 179 180 181 182 183 184 185

234 233 232 231 230 229 228 227 226

235 236 237 238 239 240 241 242 243

292 291 290 289 288 287 286 285 284

293 294 295 296 297 298 299 300 301

350 349 348 347 346 345 344 343 342

031 032 033 034 035 036 037 038 039 040

050 049 048 047 046 045 044 043 042 041

070 071 072 073 074 075 076 077 078 079

109 108 107 106 105 104 103 102 101 100

128 129 130 131 132 133 134 135 136 137

167 166 165 164 163 162 161 160 159 158

186 187 188 189 190 191 192 193 194 195

225 224 223 222 221 220 219 218 217 216

244 245 246 247 248 249 250 251 252 253

283 282 281 280 279 278 277 276 275 274

302 303 304 305 306 307 308 309 310 311

341 340 339 338 337 336 335 334 333 332

080 081 082 083 084 085 086 087 088 089

099 098 097 096 095 094 093 092 091 090

138 139 140 141 142 143 144 145 146 147

157 156 155 154 153 152 151 150 149 148

196 197 198 199 200 201 202 203 204 205

215 214 213 212 211 210 209 208 207 206

254 255 256 257 258 259 260 261 262 263

273 272 271 270 269 268 267 266 265 264

312 313 314 315 316 317 318 319 320 321

331 330 329 328 327 326 325 324 323 322

Poster Board Size All posters are 4 feet high by 6 feet wide.



010 009 008 007 006 005 004 003 002 001

Discussion Posters

*First authors stand by posters

Fast, Easy Registration Online  ·  AAN.com/view/am14

47



Monday, April 28 P1  Poster Session I First Authors stand by Posters from 5:00 p.m.–6:30 p.m.

3:00 p.m.–6:30 p.m.

 oster Discussion Session: Aging, Dementia, and Cognitive and Behavioral P Neurology I Utilizing a guided tour format, topic experts will lead attendees around the ten posters in the poster discussion session and facilitate questions with poster authors during the 90-minute author stand-by time.

P1.001

Complementary and Alternative Medicine Use Among Patients with Cognitive Impairment in Singapore  Wahab Hameed, Simon Kang Seng Ting

P1.004

Aerobic Physical Exercise Stabilizes Cognitive Status in NonDemented Elderly: An In-Patient Pilot Study.  Manuel Seijo-Martinez, José María Cancela Carral, Ayán Pérez Carlos

P1.007

P1.002

P1.005

P1.008

Museum-based Creative Arts Programming Is Associated with Less Dementia Patient Apathy and Better Caregiver Well-being  Hannah Roberts, Carolyn Halpin-Healy, Rebecca McGinnis, James Noble

P1.003

Evaluation of a Multidisciplinary “Brain Fitness Program” for Treatment of Cognitive Impairment with Aging  Majid Fotuhi, Mark Trullinger, Brooke Lubinski, Mehdi Ghasemi

Comparative Effectiveness of an Advanced Treatment Protocol for Dementia Versus Standard Community Care  Emilymarie Clionsky

P1.006

Extended-release Daily Memantine Provides Increasing Cumulative Benefits Across Clinical Domains Over 24 Weeks in Patients with Moderate to Severe Alzheimer’s Disease: An Analysis of Area Under the Curve  Alireza Atri, Suzanne Hendrix, Vojislav Pejovic, Stephen Graham

Predictors of Response to 13.3 mg/24 h Rivastigmine Patch in Patients with Severe Alzheimer’s Disease Martin Farlow, Carl Sadowsky, Drew Velting, Xiangyi Meng, Zahur Islam Efficacy of 13.3 mg/24 h versus 4.6 mg/24 h Rivastigmine Patch on Activities of Daily Living in Severe Alzheimer’s Disease: A Factor Analysis  Joseph Micca, Drew Velting, Xiangyi Meng

P1.009

Cognitive Efficacy of 13.3 mg/24 h versus 4.6 mg/24 h Rivastigmine Patch in Severe Alzheimer’s Disease: Severe Impairment Battery Factor Analysis  Steven Ferris, Richard Isaacson, Drew Velting, Xiangyi Meng

P1.010

Bayesian Longitudinal Modeling on Placebo Data from Alzheimer’s Disease Clinical Studies YunFei Chen, Richard Mohs, Ying Ding, Paul Aisen, Ronald Thomas

NEW! e  Poster Session: Movement Disorders I The ePoster session will feature a selection of posters to be presented digitally, rather than in the traditional format. Authors will be able to take advantage of the format to highlight compelling visual features such as images and videos. See poster map on page 47 for location.

P1.011

Validation of a Functional Biomarker of Brain Energy Deficit in Huntington Disease  Fanny Mochel, Isaac Mawusi Adanyeguh, Daisy Rinaldi, Romain Valabregue, Alexandra Durr, Pierre-Gilles Henry

P1.012

Correlating OCT Changes with Disease Severity and Cognitive Status in Parkinson’s Disease  Shirin Vartak, Thomas Guttuso, Jesper Hagemeier, Cheryl Kennedy, Rebecca Melia, Ellen Carl, David Lichter, Robert Zivadinov

General Neurology I P1.021

AML Presenting as Autonomic Autoimmune Ganglionopathy  Joel Phillips, Elmoatazbellah Ibrahim, Mirela Cerghet, Naganand Sripathi, Javier Arias-Stella III

P1.022

Extensor Posturing and a Cingulate Gyrus Lesion: An Unusual Case  Atul Ramesh, Daniel Labovitz, Shouri Lahiri, Alexis Boro

48

P1.013

Deep Brain Stimulation in X-linked Dystonia-Parkinsonism (DYT3/ Lubag): Partial Results from a Prospective Trial of 12 Cases  Aloysius Domingo, Norbert Brüggemann, Roland Dominic Jamora, Cid Diesta, Jose Aguilar, Simone Zittel, Anne Weissbach, Dirk Rasche, Alexander Münchau, Raymond Rosales, Lillian Lee, Volker Tronnier, Christine Klein

P1.015

P1.014

Progressive Supranuclear Palsy (PSP): Diagnosis Through Skin Biopsy  Ildefonso Rodriguez-Leyva, Ana Calderon-Garcidueñas, Martha Santoyo, Erika Chi, Verónica Medina-Mier, Maria Jimenez-Capdeville

P1.016

P1.023

P1.025

Neurologic Imaging and Electroencephalogram Findings After Chasing the Dragon  Kelly Andrzejewski, Michael Devereaux

P1.024

Trends in Outcome and Cost of Hospitalization of Mechanically Ventilated Adult Myasthenia Gravis Patients from 1992 to 2009  Weizhen Wang, Ankit Pahwa, Nizar Souayah

Parkinson Risk in Ashkenazi Jewish Gaucher Patients and GBA Heterozygotes: Is There a Gene Dose Effect?  Roy Alcalay, Tama Dinur, Timothy Quinn, Karina Sakanaka, Oren Levy, Cheryl Waters, Stanley Fahn, Tsvyatko Dorovski, Wendy Chung, Michael Pauciulo, William Nichols, Huma Rana, Manisha Balwani, Louise Bier, Deborah Elstein, Ari Zimran Combined Fenobam and Amantadine Signigficantly Reduce Levodopa-Induced Dyskinesia in the 1-Methyl-4-Phenyl-1,2,3,6Tetrahydropyridine (MPTP)-Lesioned Primate Model of Parkinson’s Disease  Maurizio Facheris, Wai Kin D Ko, Elsa Pioli, Qin Li, Steve McGuire, Alison Urkowitz, Audrey Dufour, Erwan Bezard, Todd Sherer

Assessment of Mortality in Sporadic Inclusion Body Myositis: A Delphi Panel Technique  Victoria Barghout, Mark Price, Olivier Benveniste, Lisa ChristopherStine, Alastair Corbett, Marianne De Visser, David Hilton-Jones, John Kissel, Thomas Lloyd, Ingrid Lundberg, Frank Mastaglia, Tahseen Mozaffar, Merrilee Needham, Jens Schmidt, Kumaraswamy Sivakumar, Carla Demuro, Brian Tseng

2O14 Scientific Abstract Listing and Annual Meeting Information

P1.017

Quantifying Musician Performance using MIDI Analysis Before and After EMG-Guided Botulinum Toxin Injections for Focal Task-Specific Dystonia  Miriam Sklerov, Sarah Boschung, Seth Pullman

P1.018

Kinematic Assessments Effectively Guide Botulinum Neurotoxin Type A Injections For Essential Tremor Treatment  Jack Lee, Fariborz Rahimi, Olivia Samotus, Mandar Jog

P1.019 WITHDRAWN P1.020 WITHDRAWN

P1.026

Neurologic Involvement in Val122 Ile Familial Amyloidosis  Sami Khella, Brian Drachman, Patricia Divito, Michael Polydefkis, Thomas Brannagan, Daniel Judge, Mathew Maurer

P1.027

Paraneoplastic Cerebellar Degeneration with Castleman Disease: A Case Report  Sarah Lee, Scheherazade Le

Poster Session I Search for Autoantibodies Targeting the Nodes of Ranvier in Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Panos Stathopoulos, Harry Alexopoulos, Angie Biba, Domna Karagogeos, Marinos Dalakas

P1.029

Barriers to Discharge: A Quality Improvement Project  Anh-Thu Tran, Thuy-Anh Vu, Sandeep Kahlon

P1.030

NAIL-ing the Diagnosis: Real Neurologists Pay Attention to the Nails  Shin Beh, Teresa Frohman, Amy Conger, Darrel Conger, Laura Balcer, Peter Calabresi, David Zee, Elliot Frohman

P1.031

Cancer Risks Among the Users of Ergot-Derived Dopamine Agonists for Parkinson’s Disease: A Population-Based Case-Control Survey  Vinchi Wang, Chao Tzu-Hao

P1.032

Modulation of the Default-Mode Network and the Attentional Network by Self-Referential Processes in Patients with Disorder of Consciousness  Mirta Villarreal, Verónica Mäki-Marttunen, Lisandro Olmos, Ramón Leiguarda

P1.033

P1.042

The Underlying Mechanisms of Autophagy in Age-related Sensitivity to Parkinsonian Pathogenesis  Ya-Ping Yang, Hui-Fen Zheng, Cheng-Jie Mao, Fen Wang, Li-Fang Hu, Chun-Feng Liu

P1.043

The Role of AlphaSynuclein Oligomerisation in Parkinson’s Disease  Sonia Gandhi, Mathew Horrocks, Plamena Stroh, Marthe Ludtmann, Emma Deas, Nicholas, W Wood, David Klenerman, Andrey Abramov

P1.044

Generation of Alpha Synuclein (Snca) Cell Models for High-Throughput Drug Screening Using Zinc-Finger Nuclease Technology  Warunee Dansithong, Khanh Thai, Sharan Paul, Stefan Pulst, Duong Huynh

P1.045

Ataxin-2 (Atxn2) Regulates Rgs8 Expression via Rna Interaction  Sharan Paul, Warunee Dansithong, Stefan Pulst

P1.046 Sodium-Potassium

Atpase Inhibitors as Inhibitors of Atxn2 Expression  Daniel Scoles, Lance Pflieger, Thomas Dexheimer, David Maloney, Anton Simeonov, Ajit Jadhav, Stefan Pulst

Ehlers-Danlos Syndrome and Postural Tachycardia Syndrome: A Relationship Study  Daniel Wallman, Anna Hohler, Janice Weinberg

P1.047

P1.034

P1.048

Postural Tachycardia Syndrome Associated with Ferritin Deficiency  Daniel Wallman, Anna Hohler, Janice Weinberg, Zetta Fayos

P1.035

How Safe Is Acute High Dose Corticosteroid Therapy in Neurological Disorders?  Itai Lotan, Liora Fireman, Avi Weizman, Israel Steiner

P1.036

A Case of Paraneoplastic Cerebellar Degeneration Associated with Non-Cutaneous Metastastic Merkel Cell Carcinoma  Cen Zhang, Eric Lancaster

P1.037

Expanding the Clinical Spectrum of Neuromyelitis Optica: Three Cases with Brainstem Involvement Faria Amjad, Sean Gratton, Benjamin Osborne, Carlos Mora, Carmelo Tornatore

P1.038

Longitudinally Extensive Spinal Cord Osmotic Myelinolysis Lina Rodriguez, Scott Silliman

P1.039

A Diagnostic Algorithm for Paroxyasmal Kinesigenic Dyskinesia Jasita Sachar, Krishe Menezes, A. Rothner

P1.040

Two-Year Experience of Neuronal Surface Antibodies Mediated Encephalitis Diagnostic Screening in 450 Patients_A Single Center Study from China  Lei Liu, Jiawei Wang

Movement Disorders: Basic Mechanisms P1.041

Cellular Response to Deep Brain Stimulation in a Rat Model Vinata Vedam-Mai, Massoud Baradaran-Shoraka, Alex Mafdali, Sara Ardila, Eun Mi Kim, Jamie Schwarz, Brent Reynolds, Michael Okun

Co-expression Networks in Generation of Induced Pluripotent Stem Cells (Ipscs)  Lance Pflieger, Sharan Paul, Fuying Gao, Giovanni Coppola, Stefan Pulst Optical Coherence Tomography in Parkinson’s Disease: Retinal Structural Injury and Insights Into Disease Pathology  Aashka Shah, Jessica Chorostecki-Vigrass, Ginny Bao, Fen Bao, Carla Santiago Martinez, Veronica Gorden, Christina Caon, Edwin George, Natalya Shneyder, Navid Seraji-Bozorgzad, Shana Krstevska, Elliot Frohman, Omar Khan

P1.049

Rare Variant Pathway Analysis Highlights the Importance of Lysosomal Pathways in Parkinson Disease Jeffery Vance, Karen Nuytemans, Gary Beecham, Vanessa Inchausti, LizMarie Maldonado, Eden Martin, William Perry, Liyong Wang, Margaret Pericak-Vance, William Scott

P1.050

The Relationship Between Dietary Intake, Nutrition Status and Huntington’s Disease Severity Esther Cubo, Jessica Rivadeneyra, Natividad Mariscal, Diana Armesto, Ana Mateos, Rafael Camara

Neuromuscular Disease: Basic Science P1.051

Neuronal Activity Drives Presynaptic pH Regulation: Insights from Live Fluorescent pH Imaging in Drosophila Melanogaster Motor Nerve Terminals.  Adam Rossano, Gregory Macleod

P1.052

Familial Amyotrophic Lateral Sclerosis with Novel p62 Immunopositive Intra-Neuronal Nuclear and Axonal Spheroid Inclusions  Raphael Schneider, Phedias Diamandis, Lorne Zinman, Ekaterina Rogaeva, Janice Robertson, Julia Keith

P1.053

Long-term Electrophysiologic Assessment of a Mild Mouse Model of Spinal Muscular Atrophy  Seward Rutkove, Jia Li



P1.054

A Mouse Model of Adult Polyglucosan Body Disease (Apbd), a Late Onset Variant of Glycogen Storage Disease Type IV (GSD IV).  Hasan Akman, Valentina Emmanuele, Sindu Krishna, Salvatore DiMauro

P1.066

P1.055

Paraneoplastic Antibodies in Patients with Amyotrophic Lateral Sclerosis  Michael Rosario, Richard Bedlack

P1.067

P1.056 Autopsy-proven

P1.068

Amyotrophic Lateral Sclerosis Coexisted with Parkinson Disease: A Novel Association of TDP-43 Proteinopathy and α-Synucleinopathy  Yuishin Izumi, Hiroyuki Sumikura, Koji Fujita, Masaki Kamada, Yoshimitsu Shimatani, Ryosuke Miyamoto, Hidetaka Koizumi, Yoshimichi Miyazaki, Hiroyuki Hatsuta, Hiroyuki Nodera, Yoshihiko Nishida, Shigeo Murayama, Ryuji Kaji

P1.057

Genetic Background Effects on Lifespan of Dynactin P150 Glued Mouse Models of Motor Neuron Disease Terry Heiman-Patterson, Juliann Jiang, Philip Wong, Guillermo Alexander, Elizabeth Blankenhorn

P1.058

Oligomerization of ZASP, a Myofibrillar Myopathy Gene Product, in Vitro and in Vivo  Lisa Brubaker, Rachel Ohman, Ian Chow, Xiaoyan Lin, Ami Mankodi

P1.059

Pathogenic Antigen-Specific Th17 Cells Drive Autoimmunity Myasthenia Gravis  Yonghao Cao, Margarita Dominguez-Villar, Robert Amezquita, Shuqiang Liu, Steven Kleinstein, Jonathan Goldstein, Richard Nowak, Kevin O’Connor

P1.060

IgG from Guillain-BarréSyndrome (GBS) Patients Alter Autonomic Nerve Fiber Function in Mice Christian Ritter, Ilja Bobylev, Abhijeet Joshi, Gereon Fink, Helmar Lehmann

Neuropathy: Animal Models and Experiments P1.061

Characterization of a New Animal Model of Chronic Inflammatory Demyelinating Polyneuropathy Laurent Kremer, Susana Brun, Wissam Beaino, Omar Taleb, Chanh Dao Lam, Nicolas Collongues, Elisabeth Trifilieff, Jerome De Seze

P1.062

CCR2 Gene Deletion and Pharmacologic Blockade Ameliorate a Severe Murine Experimental Autoimmune Neuritis Model of Guillain-Barré Syndrome.  Eroboghene Ubogu

P1.063

Segmental Demyelination in Fig4 Deficiency  Bo Hu, Qing Yan, Jun Li

P1.064

Phenotype in the Heterozygous R98C Knock-in Mouse Model of CMT1B Is not Improved by Neuregulin 1 Type III Overexpression  Yunhong Bai, Chiara Pisciotta, Suola Wang, Xingyao Wu, Laura Feltri, Lawrence Wrabetz, Michael Shy

P1.065

Disruption of Myelin Junctions and Increase of Myelin Permeability in PMP22 Deficiency  Bo Hu, Jiasong Guo, Yang Yang, Leiming Wang, Jiawen Wu, Sezgi Arpag, Bruce Carter, Ueli Suter

Induced Pluripotent Stem Cell Based Models of CMT1A and HNPP Robert Baloh, Irina Epifantseva, Kevin Kim, Shaughn Bell, Sharon Carmona, Sharday Grant, Megan Simpkinson, Matthew Harms, Dhruv Sareen, AKMG Muhammad The Effect of Hyperglycemia on Human Schwann Cells  Nizar Souayah, Hongxin Chen The Effect of Glucose on the Response of Peripheral Nerve to Anoxia  Mark Stecker, Matthew Stevenson

P1.069

Noninvasive Peroneal Sensory and Motor Nerve Conduction Studies in the Rabbit Distal Hindlimb: Feasibility, Variability and Response to Vincristine  John Hotson

Neuromuscular Disease: Pathogenesis and Pathology P1.070

NADPH Oxidases (NOX) Enzymes Induced Oxidative Stress in CIDP Patients  Andrea Calvo, Giuseppe Marrali, Paolina Salamone, Federico Casale, Paolo Cugnasco, Cristina Caorsi, Antonio Amoroso, Leonardo Lopiano, Adriano Chio, Dario Cocito

P1.071

New Markers For Demyelination in Diabetic Neuropathy: A Novel Strategy  Nizar Souayah, Ankit Pahwa, Hongxin Chen

P1.072

Spinal Nerve Root Hypertrophy as Etiology of Back Pain in CIDP  Alexis Shaefer, Mohammad Alsharabati, Gwendolyn Claussen, Shin Oh

P1.073

Investigating the Amyloid Properties of TDP-43 in ALS and FTLDTDP  Shan Desai, Eileen Bigio

P1.074

Pulsatile TH2 Shift of Recovering TCR-Vβ Expanded T-Helper Effector Cells After Initiation of IVIG Treatment in CIDP  Martin Russwurm, Michael Pütz, Tine Höft, Kerstin Schlegel, Michael Happel, Christian Eienbröker, Maria Seipelt, Bjorn Tackenberg

P1.075

The Investigation of Effects of Alpha Lipoic Acid in the Sciatic Nerve and Brain Tissue of Rats Were Created in Experimental Diabetes  Muhammed Said Berilgen, Irem Tasci, Murat Gonen

P1.076

Post Mortem Measurement of Intra-Epidermal Nerve Fiber Density: A Novel Research Tool  Christopher Taicher, Eugene Dulaney, Felix Eckenstein, Michael Hehir, Waqar Waheed, Julian Sprague, Rup Tandan

P1.077

Clinicopathologic Analysis of TDP-43 Expression in the Cerebral Cortex in ALS  Ryoko Takeuchi, Mari Tada, Atsushi Shiga, Takuya Konno, Yasuko Toyoshima, Osamu Onodera, Masatoyo Nishizawa, Akiyoshi Kakita, Hitoshi Takahashi

P1.078

Morphological and Mechanical Abnormalities Detected in Tissue-Engineered Reconstructed Skin Equivalents Derived from ALS Patients  Nicolas Dupre, Peter Gould, Stephan Saikali, Francois Gros-Louis

Fast, Easy Registration Online  ·  AAN.com/view/AM14

49

Monday April 28

P1.028



Monday, April 28 Iatrogenic Spinal Cord Infarction in the Central Artery Distribution Following Cervical Foraminotomy Thananan Thammongkolchai, Pichet Termsarasab, Bashar Katirji

Autonomic Neuropathy

Anterior Horn Cell Disease: Pathogenesis and Pathology

P1.090

P1.079

P1.080

Role of NOX2 Enzyme Activity in Neuroinflammation: Preliminary Results in Amyotrophic Lateral Sclerosis and Parkinson’s Disease  Andrea Calvo, Paolina Salamone, Giuseppe Marrali, Federico Casale, Giuseppe Fuda, Cristiana Caorsi, Antonio Amoroso, Maurizio Zibetti, Mario Rizzone, Leonardo Lopiano, Adriano Chio

P1.081

Fast Skeletal Muscle Troponin Activator Tirasemtiv Increases Muscle Function and Performance in the B6SJLSOD1G93A ALS Mouse Model  Fady Malik, Darren Hwee, Adam Kennedy, Julie Ryans, Jeffrey Jasper

P1.082

“Reporting Biomarkers” in ALS: Experiences from a Pilot Compassionate Use Program Applying G-CSF—Mobilized Hematopoietic Stem Cells in ALS-Patients  Ines Kobor, Dobri Baldaranov, Andrei Khomenko, Siw Johannesen, Jochen Grassinger, Katja Kollewe, Susanne Petri, Jan Kassubek, Albert Ludolph, Michael Deppe, Gerhard Schuierer, Tim-Henrik Bruun, Wilhelm Schulte-Mattler, Ulrich Bogdahn

P1.083

Mutations in ERBB4 That Disrupt the NRG-ErbB4 Pathway Cause Autosomal Dominant Familial ALS Type 19  Yuji Takahashi, Yoko Fukuda, Jun Yoshimura, Atsushi Toyoda, Kari Kurppa, Hiroyoko Moritoyo, Veronique Belzil, Klaus Elenius, Guy Rouleau, Asao Fujiyama, Shinichi Morishita, Jun Goto, Shoji Tsuji

P1.084

Does Altered Growth Hormone Secretion Underlie the Development of Hypermetabolism in Amyotrophic Lateral Sclerosis: Studies in HSOD1G93A Mice  Pamela McCombe, Shyuan Ngo, Frederick Steyn

P1.085

Familial Adult Spinal Muscular Atrophy Associated with VAPB Gene  Marcos de Freitas, Victor Kosac, Osvaldo Nascimento, Frederico Prado

P1.086

Is the Decrease in PGC1Α Detected in ALS Patients an Up Stream Effector or a Byproduct of Mitochondrial Dysfunction?  Rawan Albadareen, Russell Swerdlow

P1.087

Atypical Features in a Spinal and Bulbar Muscular Atrophy Patient with a 68 CAG Repeat  Christopher Grunseich, Ilona Kats, Laura Bott, Ke-lian Chen, Angela Kokkinis, Carlo Rinaldi, Kenneth Fischbeck

P1.088

Phosphorylated Tau Is a Candidate Biomarker for Amyotrophic Lateral Sclerosis  Murray Grossman, Lauren Elman, Leo McCluskey, Corey McMillan, Ashley Boller, John Powers, Katya Rascovsky, William Hu, Leslie Shaw, David Irwin, Virginia Lee, John Trojanowski

50

P1.089

Carbidopa: A Novel Approach to Treating Paroxysmal Hypertension in Afferent Baroreflex Failure  Lucy NorcliffeKaufmann, Jose-Alberto Palma, Jose Martinez, Horacio Kaufmann Cardiac Sympathetic Denervation Without Lewy Bodies in a Case of Multiple System Atrophy Glen Cook, Patricia Sullivan, Courtney Holmes, David Goldstein

P1.091

Early Predictors of Delayed Neurocardiogenic Syncope in Tilt Table Testing  Mohammed Hussain, Derrick Blackmore, Bilal Qarni, Zaeem Siddiqi

P1.092

Gastrointestinal Dysmotility in Postural Tachycardia Syndrome Adam Loavenbruck, Wolfgang Singer, David Sletten, Phillip Low, Adil Bharucha

P1.093

Co-Morbidities of Neuropathic Postural Orthostatic Tachycardia Syndrome and of the Autonomic Neuropathies Kamal Chemali, Kevin Mc Neeley

P1.094

Delayed Orthostatic Hypotension: Implications for Autonomic Testing and Prognosis Christopher Gibbons, Roy Freeman

P1.095

Disproportionate Pupillary Impairment in Diabetic Autonomic Failure  Doyle Yuan, Elaine Spaeth, Steven Vernino, Srikanth Muppidi

P1.096

Determinants of Vagal Baroreflex sensitivity and Normative Data  Naoki Wada, Wolfgang Singer, Tonette Gehrking, David Sletten, Phillip Low

Cerebrovascular Disease and Interventional Neurology: Translational Science P1.097

Carotid Wall Tension and White Matter Lesion  Katsuhiko Kohara, Yoko Okada, Masayuki Ochi, Tokihisa Nagai, Michiya Igase, Tetsuro Miki

P1.098

Effects of Memantine and Clopidogrel Alone and in Combination on Cerebral Ischemia in Rats  Hasan Özdemir, Selçuk Ilhan, Caner Demir, Bekir Akgün, Oktay Kapan, Ataş Eser, Muhammed Said Berilgen, Metin Balduz

P1.099

Post-stroke Administration of Ethanol and Normobaric Oxygen Preserves Oxidative Metabolism by Modulating Pyruvate Dehydrogenase Complex in Transient and Permanent Ischemic Stroke  Omar Elmadhoun, Changya Peng, Xiaokun Geng, Murali Guthikonda, Yuchuan Ding

P1.100 PKC-δ and Akt Signaling

in Reduced Apoptosis by Ethanol After Transient Ischemic Stroke  Adam Hafeez, Xiaokun Geng, Murali Guthikonda, Yuchuan Ding

P1.101

The Importance Of Measuring Cerebrospinal Fluid Biomarkers In Cardiac Arrest Survivors  Hans Rosén, Christoffer Rosén, Ulf Andreasson, Daniel Bremell, Rosemary Bremler, Lars Hagberg, Lars Rosengren, Kaj Blennow, Henrik Zetterberg

3:00 p.m.–6:30 p.m. P1.102

The Effect of Tissue Plasminogen Activator on the Rodent Brain Proteome  Zamir Merali, Meah Gao, Tim Bowes, Jian Chen, Andrea Kassner

P1.114

P1.103

P1.115

Increased Frequency of Circulating BDBF+ T Regulatory Cells in Subjects with Acute Ischaemic Stroke  Pamela McCombe, Jun Yan, Judith Greer

P1.104

Hemorheology of Clinically Silent Multifocal Vascular Cerebral Lesions  Piotr Kowal, Izabela Siemieniak, Anna Marcinkowska-Gapińska Factor VIII as a Predictor of Stroke Etiology  Michael Halstead, Ambert Yeh, Laurie Schluter, Dominique Monlezun, Jr, Alexander George, Corinne Schild, Ramy El Khoury, Sheryl Martin-Schild

Neuroprotection Against Ischemic Brain Injury with Methylene Blue  Julio Rojas, Erik Plautz, Ann Stowe, Mark Goldberg

Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Subtype

P1.105

P1.116

Cerebrovascular Disease and Interventional Neurology: Antiplatelet Agents and Miscellaneous

P1.117

Impact of Stroke on Aβ1-40 and Aβ1-42 Plasmatic Levels Solene Moulin, Didier Leys, Susanna SchraenMaschke, Regis Bordet

P1.106

A Concentration Response Relationship Between the Active Metabolite of Clopidogrel and its Antiplatelet Activity  Francis Gengo, Steve Wolff, Erica Westphal, Michelle Rainka, Vernice Bates

P1.107

Topical Diclofenac Does Not Affect the Antiplatelet Properties of Aspirin as Compared to the Intermediate Effects of Oral Diclofenac: a Prospective, Randomized, Complete Crossover Study  Francis Gengo, Nezami Brigette, Erica Westphal, Michelle Rainka, Meghan Rowcliffe, Vernice Bates

P1.108

Platelet Response to Increased Aspirin Dose in Patients Whose Platelets Were Non-Responsive to Lower Aspirin Doses  Erica Westphal, Francis Gengo, Michelle Rainka, Matt Robson, Maurice Hourihane, Vernice Bates

P1.109

Clopidogrel Enhances Platelet Responsiveness to Aspirin  Erica Westphal, Francis Gengo, Michelle Rainka, Lisa Kurczewski, John Hourihane, Vernice Bates

P1.110

Safety and Efficacy of Fondaparinux for Venous Thromboembolism Prophylaxis After Acute Ischemic Stroke  Santosh Ramanathan, Konark Malhotra, Chris Hackett, Melissa Tian, Matthew Quigley, David Wright, Crystal Wong, Ashis Tayal

P1.111

Primary Prevention of Stroke in Argentina: a Missed Opportunity? Data from the ARENAS Registry  Ana Atallah, Osvaldo Fustinoni, Ricardo Beigelman, Maria Zurru, Sebastian Ameriso, Juan Cirio, Guillermo Burry

P1.112

Combination Therapy of Intravenous Glycoprotein IIB-IIIA Inhibitors and Tissue Plasminogen Activator for Acute Ischemic Stroke  Anshudha Sawhney, Divyanshu Dubey, Chirantan Banerjee

P1.113

Updated Meta-analysis of Hemodilution in Acute Ischemic Stroke  Timothy Chang, Matthew Jensen

2O14 Scientific Abstract Listing and Annual Meeting Information

Cryptogenic Stroke with More than One Cause Versus No Cause by TOAST Classification Lacks Adequate Predictive Power for Stroke Risk Factors and Outcomes  Tyler Scullen, Dominique Monlezun, Jr, Alexander George, James Siegler, Melissa Schwickrath, Ramy El Khoury, Sheryl Martin-Schild Compare the Functional Outcome in Ischemic Strokes Based on the TOAST Classification.  Anand Patel, Zabeend Mahuwala, Kaustubh Limaye, Nicolas Bianchi, Archana Hinduja, Rajan Patel

P1.118

Cryptogenic Stroke with No Cause Demonstrates the Outcome Prediction Utility of TOAST Classifications in a Large Stroke Patient Sample Tyler Scullen, Dominique Monlezun, Jr, Alexander George, James Siegler, Melissa Schwickrath, Ramy El Khoury, Sheryl Martin-Schild

P1.119

GCS Greater than NIHSS Baseline and TOAST Predicts Better Outcomes in Stroke Patients Adam Friedant, Dominique Monlezun, Jr, Alexander George, Ramy El Khoury, Sheryl Martin-Schild

P1.120

Stroke of Cryptogenic Greater than One Cause_Shared Major and Minor TOAST Classifications  Shoichi Shimamoto, Dominique Monlezun, Jr, Tyler Scullen, Alexander George, Corbin Pomeranz, James Siegler, Melissa Schwickrath, Ramy El Khoury, Sheryl Martin-Schild

P1.121

Stroke Risk Factors, Subtypes, and 30-Day Case Fatality in Abuja, Nigeria  Sunday Bwala

P1.122

Seasonal Differences and Circadian Variation in Stroke Occurrence and Stroke Subtypes  Rohit Bhatia, Kishan Raj, Mamta Singh, M Padma, Kameshwar Prasad

P1.123

Cross-Border Acute Ischemic Stroke Subtype Comparison Between Hispanics and Mexican Mestizos Mario Cerdan-Trevino, Leonel Cantu-Martinez, Ramiro Mora-Villalvazo, Hector Martinez, Richard Hughes, Sharon Poisson

P1.124

Hypercoagulability and Vasculitis Unlike Cardioembolic Etiology Predict Bilateral Infarcts  David Lorance, Dominique Monlezun, Jr, Alexander George, Sheryl Martin-Schild, Ramy El Khoury

Poster Session I

P1.125

Utility of Workup for Thrombophilias in a Single Center—A Qualitative Perspective  Akshay Shah, Nicolaas Anderson, Kendra Drake, Maria Proytcheva, Bruce Coull

Cerebrovascular Disease and Interventional Neurology: Atrial Fibrillation and Miscellaneous P1.126

Thoracoscopic Pulmonary Vein Isolation and Atrial Appendage Ligation (TPVIAL) versus Medical Management in Atrial Fibrillation Patients with Prior Stroke  Michael Waters, Vishunmurthy Hedna, Anna Khanna, William Miles, Catherine Price, Ilona Schmalfuss, Debra Robertson, Ashkan Karimi, Thomas Beaver

P1.127

Neuroanatomical Correlates of Atrial Fibrillation: A Longitudinal MRI Study  Aveen Saed, Nudrat Tasneem, Malik Adil, Mushtaq Qureshi, Adnan Qureshi

P1.128

Prognostic significance of Baseline EKG findings and its Association with Future Vascular Event  Anmar Razak, Vishal Jani, Syed Hussain, Abraham Maaz, Ali Saeed, Adnan Sadar, Adil Malik, Adnan Qureshi

P1.129

Sinus Bradycardia Localizes Where?  Johanna Hamel, Trenton Tollefson

P1.130

Frequency of Atrial Arrhythmias in Stroke: Prolonged Monitoring of Cardiac Rhythm for Detection of Atrial Fibrillation After a Cerebral Ischemic Event (PEAACE) study Yaseen Ibrahim, Ghazala Basir, Esseddeeg Ghrooda, Askar Mohammad, Nazim Khan, Peter Dobrowolski, Sajad Ghualmhusein, Ashfaq Shuaib

P1.131

Diagnostic Yield of Prolonged Cardiac Rhythm Monitoring in Cryptogenic Stroke  Rizwan Kalani, Richard Bernstein, Yvonne Curran, Ilana Ruff, Shyam Prabhakaran

P1.132

Gaze Deviation in Acute Stroke: Neuroimaging Evidence, Significance and Clinical Correlation  Nabeel Herial, Rema Raman, Karin Ernstrom, Clarity Coffman, Konrad Schlick, Karen Rapp, Royya Modir, Dawn Meyer, Thomas Hemmen, Brett Meyer

P1.133

Development of National Web-based Registry for Acute Stroke  Leopold J Streletz, Naveed Akhtar, Saadat Kamran, Dirk Deleu

P1.134

Revascularization in Acute Ischemic Stroke Based on Clinical-Diffusion Mismatch (REVASC): A Planned Phase I Trial  Nazli Janjua

P1.135

Stroke and Cerebrovascular Risk Factors Knowledge in Patients Admitted to a Cardiovascular Ward.  Francisco Muñoz Giacomelli, Maria Gonzalez Toledo, Fatima Pagani Cassara, Agustina Tamargo, Alejandro Thomson, Diego Nadile, Andres Ferre, Francisco Klein

Cerebrovascular Disease and Interventional Neurology: Rehabilitation and Recovery P1.136

Inter-individual Variability in Motor and Language Recovery During the Acute Stroke Period  Ronald Lazar, Lauren Dunn, Adam Schweber, Daniel Manson, Andrea Lendaris, Randolph Marshall

P1.137

Factors Influencing SelfPerception of Recovery from Stroke in Comparison to Objective Assessments  T. Keta Hodgson, Randy Sanoff, Gillian Devereux, Star Feudi, Samantha Cherin, Fiona Chatfield, Robin Conwit, Scott Hamilton, Nerses Sanossian, Sidney Starkman, Jeffrey Saver

P1.138

Use of HIRREM, a NonInvasive Neurotechnology, Is Associated with Improved Autonomic Function and Decreased Temporal Hemispheric Asymmetry in A 67 Year Old Male with a Recent Stroke  Charles Tegeler, Jared Cook, Catherine Tegeler, Sung Lee, Jasmyn Nicholas, Hossam Shaltout

P1.139

A Randomized Control Trial of Granulocyte Colony Stimulating Factor (G-CSF) Intervention in Acute Ischemic Stroke to Improve Functional Outcome  Sankar Gorthi, Dheeraj Nauwhar, Pawan Gupta, Kaukab Hassan

P1.140

Statin Therapy Reduces Oxidized Low Density Lipoprotein and Associate with Favorable Outcome in Patients After Acute Ischemic Stroke NaiWen Tsai

P1.141

WITHDRAWN

P1.142

Cortical Activity Modulation by Botulinum Toxin Type A in Patients with Post-Stroke Arm Spasticity: Real and Imagined Hand Movement  Petr Hlustik, Tomas Veverka, Pavel Hok, Zbynek Tudos, Pavel Otruba, Alois Krobot, Petr Kanovsky

P1.143

Satisfaction with Botulinum Toxin Treatment in Post-Stroke Spasticity: Results From Two Cross-Sectional Surveys of Patients and Physicians Djamel Bensmail, Angelika Hanschmann

P1.144

Long Lasting Therapeutic Effects of Yoo’s Solution for Ischemic Stroke  Seo Hong Yoo

Cerebrovascular Disease and Interventional Neurology: Intracranial Disease P1.145

CT Angiography Alone Can Provide Sufficient Angio-Architectual Information About Unruptured Intracranial Aneurysms to Proceed Straight to Treatment  David Ben-Israel, David TurkelParrella, Ekaterina Kouzmina, Thomas Marotta, Julian Spears, Airton Leonardo de Oliveira Manoel

P1.146

Treatment Trends in Management of Intracranial Stenosis in The Pre- and Post-Sammpris Era Swaroop Pawar, Tanya Turan, George Cotsonis, Michael Lynn, Rahim Wooley, Barney Stern, Colin Derdeyn, David Fiorella, Marc Chimowitz



P1.147

Association Between Lipoprotein (a) Levels and Vascular Events in the Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) trial.  Swaroop Pawar, Tanya Turan, Marc Chimowitz

P1.148

Comparison of Intracranial Stent Placement and Best Medical Treatment Alone for Treatment of Symptomatic Intracranial Stenosis Vikram Jadhav, Mushtaq Qureshi, Adnan Qureshi

P1.149

Impact of SAMMPRIS trial on Intracranial Stent Placement: A State Wide Study  Farhan Siddiq, Malik Adil, Saqib Chaudhry, Adnan Qureshi

P1.150

Trends in Cerebral Blood Flow Velocities of Patients with Intracranial Atherosclerotic Disease  Shawna Cutting, Tatjana Rundek, Victor Del Brutto, Sebastian Koch, Ralph Sacco, Jose Romano

P1.151

Association Between Intracranial Stenosis and Cerebro-renal Microvascular Damage in a Latin American Cohort.  Maria Zurru, Claudia Alonzo, Laura Brescacin, Pigreti Santiago, Luis Camera, Gabriel Waisman, Edgardo Cristiano

P1.152

Stroke Among Hospitalized Patients Diagnosed with Vertebrobasilar Insufficiency: A Retrospective Cohort Study  Li Yang, Harrison Bai, Xin Zhao, Yanqiao Xiao, Yuanyuan Yang, Scott Kasner, Liming Tan

P1.153

Long-term Stroke Recurrence in Patients with Basilar Artery Occlusion.  Michael Ruff, Tamika Burrus, Alejandro Rabinstein

P1.154

Postprandial Clearance of Oxidized LDL in Stroke-related Atherosclerosis  Julia Rothlisberger, NgocAnh Le, Christy Cassarly, Renee Martin, Tanya Turan

CNS and Disease Mechanisms in Humans and Animal Models P1.155

Oligodendrocyte Progenitor Cells (OPCs) from Adult Human Brain Expressed Distinct MicroRNAs Compared to OPCs in Development  Soo Yuen Leong, Vijayaraghava Rao, Jenea Bin, Pavel Gris, Mugundhine Sangaralingam, Timothy Kennedy, Jack Antel

P1.156

Astrocyte-derived VEGF-A Drives Blood-brain Barrier Disruption in CNS Inflammatory Disease.  Azeb Argaw, Linnea Asp, Jingya Zhang, Trinh Pham, John Mariani, Dipankar Dutta, Elisabeth Kramer, Napoleone Ferrara, Michael Sofroniew, Gareth John

P1.157

Cytokine Influence on Oligodendrocyte Progenitor Cell Proliferation  Robert Knobler

P1.158

Latent Infection of the Central Nervous System (CNS) and the ‘Inside-Out’ Model of Multiple Sclerosis (MS) Lorne Kastrukoff, Allan Lau, Eva Thomas

P1.159

Protease-activated Receptor-1 (PAR-1) and Interleukin-1Beta Act Synergistically in Granzyme b Mediated Neurotoxicity  Paul Lee, Avindra Nath

P1.160

Myelin Sulfatides Modulate T Cell Function During Autoimmune Demyelination  Marcin Mycko, Beata Sliwinska, Maria Cichalewska, Hanna Cwiklinska, Krzysztof Selmaj

P1.161

Neuroendocrine Dysregulation of the T Cell Response in Early Multiple Sclerosis  Dina Hartmann, Michael Pütz, Kerstin Schlegel, Christian Eienbröker, Michael Happel, Maria Seipelt, Bjorn Tackenberg

P1.162

CD16+/Perforin+ Lymphocytes (NK Cells) May Regulate Autoimmunity in Multiple Sclerosis by Cytolysis of Antigen Laden Cells in the Peripheral Blood.  Ramesh Nayak, Raymond Jacolik

P1.163

Modeling Anti-CD20 Mediated B Cell Depletion Indicates the Role of Treg in the Response to Therapy in MS  Pablo Villoslada, Sara MartinezPasamar, Elena Abad, Beatriz Moreno, Nieves Velez de Mendizabal, Ivan MartinezForero, Jordi Garcia-Ojalvo

P1.164

Development of Inflammatory Demyelinating Lesions in Mouse CNS After Injection of Cerebrospinal Fluid Derived from Progressive MS Patients  Massimiliano Cristofanilli, Daniel Gratch, Benjamin Pagano, Saud Sadiq

P1.165

Adult Neural Progenitor Cells Derived from MS Patients Differentiate into MBP Expressing Cells in the Shiverer Mouse  Massimiliano Cristofanilli, Benjamin Pagano, Daniel Gratch, Violaine Harris, Tamara Vyshkina, Saud Sadiq

P1.166 Hyperoxygenation

Differentiates Vascular Lesions from Parenchymal Lesions Using Susceptibility Weighted MRI in Mice with Experimental Autoimmune Encephalomyelitis Nabeela Nathoo, James Rogers, V. Wee Yong, Jeff Dunn

P1.167

Fgfr1 Ablation in Oligodendrocytes Reduces Disease Severity and Inflammation in the CNS in MOG35-55 Induced EAE Ranjithkumar Rajendran, Mario Giraldo Velasquez, Christine Stadelmann-Nessler, Martin Berghoff

P1.168

Brain Distribution of MS565, an Imaging Analogue of Siponimod (BAF312), in Non-human Primates Adriana Tavares, Olivier Barret, David Alagille, Thomas Morley, Caroline Papin, Ralph Maguire, Emmanuelle Briard, Yves Auberson, Gilles Tamagnan

P1.169

The Role of Class I Haplotype in the Development of Immune Mediated Brain Atrophy in a Murine MS Model  Istvan Pirko, Jeffrey Gamez, Pascal Atanga, Stephanie LaFrance, Aaron Johnson

P1.170 WITHDRAWN P1.171

Il-11 Induces Th17-Cell Responses in Patients with Relapsing Remitting Multiple Sclerosis (RRMS) Silva Markovic Plese, Xin Zhang, Yazhong Tao, Irena Dujmovic-Basuroski, Jelena Drulovic

Fast, Easy Registration Online  ·  AAN.com/view/AM14 51

Monday April 28



First Authors stand by Posters from 5:00 p.m.–6:30 p.m.



Monday, April 28 P1.172

The Peripheral Network Between Oxidative Stress and Inflammation in Multiple Sclerosis Maira Gironi, Marina Saresella, Vittorio Martinelli, Cristina Cursano, Enrica Mariani, Matilde Vaghi, Federica Piancone, Lucia Moiola, Ivana Marventano, Mario Clerici, Giancarlo Comi, Roberto Furlan

P1.185 Genome-wide

P1.173

P1.186

Impaired Immune Regulatory Function of Natural Killer (NK) Cells in Multiple Sclerosis (MS)  Catharina Gross, Andreas Schulte-Mecklenbeck, Anna Rünzi, Antia Posevitz-Fejfar, Heinz Wiendl

P1.174

Assessment of a Fluorinated Analog of N-acetylglucosamine to Promote Myelin Regeneration  Michael Keough, James Rogers, Ping Zhang, Jason Plemel, Chang-Chun Ling, V. Wee Yong

P1.175

Neuroprotective, AntiInflammatory and Immune Tolerizing Properties of Peptides Derived from Diffusion Survival Evasion Protein (DSEP)/ Dermcidin.  Jeffrey Greenstein, Timothy Cunningham

P1.176

Ingested (Oral) Tocilizumab Inhibits EAE  Staley Brod, Victoria Bauer

P1.177 WITHDRAWN P1.178

Deletion of Virus-specific T-cells Enhances Remyelination in a Model of Multiple Sclerosis  Aleksandar Denic, Bharath Wootla, Laurie Zoecklein, Moses Rodriguez

P1.179

Amelioration of Experimental Autoimmune Encephalomyelitis by RNA Polymerase 1 Inhibitor: Molecular and Cellular Mechanisms  Michael Gurevich, Rina Falb, Anat Achiron

P1.180

Stress Induced Angioplasticity Is Protective in Experimental Autoimmune Encephalomyelitis (EAE)  Vladimir Katyshev, Nilufer Esen, Svetlana Katysheva, Zakhar Serkin, Paula Dore-Duffy

P1.181

Inhibition of Hyaluronan Synthesis Protects Against EAE by Inducing CXCL12 in the CNS  Andre Mueller, Bo Hyung Yoon, Saud Sadiq

P1.182

Anti-CD20 Therapy Downregulates Lesion Formation and Microglial Activation in Pattern I and Pattern Ii Rat Models of Multiple Sclerosis Daniel Anthony, Alex Dickens, Nicholas Seneca, Sandra Campbell, Begona Checa, Veerle Kersemans, Edward Warren, Matthew Tredwell, Veronique Gouverneur, David Leppert

P1.183

Bowman-Birk Protease Inhibitor Induces Tr1 Cells and Suppress Effector Phase of EAE Disease; A Potential NOVEL Therapy for Multiple Sclerosis  Farinaz Safavi, Javad Rasouli, Elisabeth Mari, Guang-Xian Zhang, Mohamad Rostami

P1.184

Mir-155 Controls T Helper Cell Autoimmunity During Autoimmune Demyelination via Hsp40 Genes Expression  Marcin Mycko, Maria Cichalewska, Hanna Cwiklinska, Krzysztof Selmaj

52

Pharmacogenomic Study of Response to Cannabinoids in MS Spasticity Patients  Juan Ruiz, Antonio GonzálezPérez, María Isabel Garcia-Sanchez, María Eugenia Saez-Goñi, Macarena Rus Hidalgo, Miguel Lucas, Antonio Alcina, Fuencisla Matesanz, Guillermo Izquierdo Ayuso

3:00 p.m.–6:30 p.m. P1.196 Natalizumab-induced

Circulating Hematopoietic Stem Cells have Intact Progenitor Capacity Miriam Mattoscio, Benedetta Mazzanti, Simone Dal Pozzo, Richard Nicholas, Omar Malik, Riccardo Saccardi, Paolo Muraro

P1.197

Blocking LINGO-1 Does Not Affect Inflammatory Markers in the Cerebrospinal Fluid of Individuals with Multiple Sclerosis  Ann Ranger, Soma Ray, Suzanne Szak, Andrea Dearth, Normand Allaire, Diego Cadavid

Differential Impact of Natalizumab and Fingolimod on the Alpha-4/Beta-1 Expression-Related Subset Diversity of T Cells  Jorg Kraus, Katrin Oppermann, Julia Wanek, Georg Pilz, Peter Wipfler, Johann Sellner, Shahrzad Afazel, Elisabeth Haschke-Becher, Eugen Trinka, Andrea Harrer

P1.187

P1.198

Differentiating Plovamer Acetate and Glatiramer Acetate: Efficacy and Mechanism of Action in a Preclinical Model of Multiple Sclerosis Anneli Savinainen, Kenneth Crook, Timothy Crandall, Michelle Seng, Ursula Boschert, Tammy Dellovade

P1.188

Steady State Pharmacokinetics of Formulations of XP23829, a Novel Prodrug of Monomethyl Fumarate (MMF), in Healthy Subjects  Dmitri Lissin, Wendy Luo, Ezra Tai, Katie Zomorodi, Dan Chen, Son Nguyen, Yongjin Yao, Virna Kim, Joan Zou, Kenneth Cundy

P1.189

Preclinical Efficacy and Phase I Clinical Testing of ATX-MS1467, an Antigen-Specific Immunotherapy for Multiple Sclerosis  David Wraith

P1.190

The Global Neocortical Loss of Neurons in Multiple Sclerosis Daniele Carassiti, Maria Papachatzaki, Francesco Scaravilli, Klaus Schmierer

P1.191

Does Axonal Degeneration Depend on Demyelination in Chronic Multiple Sclerosis?  Daniele Carassiti, Shaima Al Zawawi, Klaus Schmierer

P1.192

Calcitriol and Interferon-beta Treatment Act Synergistically to Induce a Less Inflammatory Response in Stimulated PBMCs  Niall Stewart, Ingrid van der Mei, Bruce Taylor, Steve Simpson, Jr.

P1.193

Laquinimod Reduces Neuronal Injury Through Inhibiting Microglial Activation  Voon Wee Yong, Manoj Mishra, Janet Wang, Michael Keough, Claudia Silva, Yan Fan, Scott Sloka, Liat Hayardeny

P1.194

Cognitive Resilience in Multiple Sclerosis: Characterization of Blood Gene Expression Profiles Associated with Preserved Cognitive Function Anat Achiron, Yoram Barak, Michael Polliack, Michael Gurevich

MS and CNS Inflammatory Disease: Treatment Mechanisms of Action P1.195

Laquinimod Interferes with the Development of Follicular Helper T Cells and Germinal Center B Cells in Cns Autoimmunity  Michel Varrin-Doyer, Ulf Schulze-Topphoff, Kara Pekarek, Scott Zamvil

Suppressed Pro-Inflammatory Properties of Circulating B Cells in Patients with Multiple Sclerosis Treated with Fingolimod, Based on Altered Proportions of B-cell Subpopulations  Yusei Miyazaki, Masaaki Niino, Toshiyuki Fukazawa, Eri Takahashi, Takayuki Nonaka, Itaru Amino, Jun Tashiro, Naoya Minami, Naoto Fujiki, Shizuki Doi, Seiji Kikuchi

P1.199

Interferon-Beta Alters Monocytes and B-cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis.  Axtell Robert, Ryan Schubert, Lawrence Steinman

P1.200

Therapy with Interferon-Beta has No Impact on the T Cell Receptor Repertoire in MS Patients Thomas Dehmel, Clemens Warnke, Anne Mausberg, Manuel Lopez, Xavier Montalban, Hans Hartung, Bernd Kieseier

P1.201

Lymphocyte and Eosinophil Responses in Healthy Subjects Dosed with Tecfidera® and XP23829, a Novel Fumaric Acid Ester (FAE)  Lawrence Steinman, Robert Fox, Dmitri Lissin, Katie Zomorodi, Dan Chen, Lee Clark, Kenneth Cundy

P1.202

Laquinimod Regulates Inflammatory Gene Induction in a Human Model of Reactive Astrogliosis. Trinh Pham, Jingya Zhang, Jeremy Seto, Boris Hartmann, Liat Hayardeny Nisimov, Gareth John

P1.203

Laquinimod Modulates Genes Encoding Cell Migration in Multiple Sclerosis  Rina Zilkha-Falb, Michael Gurevich, Liat Hayardeny Nisimov, Anat Achiron

P1.204

Dimethyl Fumarate and Monoethyl Fumarate Exhibit Differential Effects on Glutathione, Keap1 and Nrf2 Activation In Vitro  Robert Scannevin, Melanie Brennan, Maria Matos, Xiaoping Hronowski, Benbo Gao, Peter Juhasz, Kenneth Rhodes

P1.205

Fumarate Esters Are Distinguished by Differential Inhibition of the NF-κB Mediated Proinflammatory Response.  Geoffrey Gillard, David Huss, John Anderson, Brian Collette, Andrea Bertolotti-Ciarlet, Robert Scannevin, Jason Fontenot

2O14 Scientific Abstract Listing and Annual Meeting Information

P1.206

Dimethyl Fumarate and Monomethyl Fumarate Are Distinguished by Non-Overlapping Pharmacodynamic Effects In Vivo  Melanie Brennan, Normand Allaire, David Huss, Patrick Cullen, Alice Thai, Suzanne Szak, Ankur Thomas, Davide Gianni, John Carulli, Jason Fontenot, Brian Wipke, Kenneth Rhodes, Robert Scannevin

P1.207

Dimethyl Fumarate and Monoethyl Fumarate Exhibit Differential Pharmacodynamic Effects and Pharmacokinetics In Vivo Robert Scannevin, Suzanne Szak, Kristopher King, Melanie Brennan, Normand Allaire, Patrick Cullen, Alice Thai, Ankur Thomas, Davide Gianni, Alexander Chou, Theresa Hillery, Brian Wipke, Liyu Yang, John Carulli, Huang Chaoran, Kenneth Rhodes

P1.208

Immunoregulation During Multiple Sclerosis Relapses. Effects of Intravenous Methylprednisolone. Vincent van Pesch, Nathalie Muls, Christian Sindic

P1.209

Arsenicals May Prevent Axonal Loss in Multiple Sclerosis: A Histopathological Study Dimitrios Papadopoulos, Nikolaos Antoniou, Katerina Tsimaratou, Vassilis Gorgoulis, Dimos Dimitrios Mitsikostas, Richard Nicholas

P1.210

B Cell Receptor Recognition of Glatiramer Acetate Is Required for Efficacy in Experimental Autoimmune Encephalomyelitis and Results in Differential Cytokine Production in MS Patients  Leila Jackson, Sean Selva, Tracy Niedzielko, Timothy Vollmer

P1.211

Pharmacokinetics and Pharmacodynamics of RPC1063 and its Metabolites in Healthy Adult Volunteers  Gregg Timony, Jennifer Brooks, Jeffrey Hartung, Fiona Scott, Allan Olson, Sheila Gujrathi, Marcus Boehm, Robert Peach

P1.212

Gene Expression Studies Comparing Glatiramer Acetate and Proposed Generics  Benjamin Zeskind, Fadi Towfic, Jason Funt, Kevin Fowler, Shlomo Bakshi, Eran Blaugrund, Sarah Kolitz, Maxim Artyomov, Michael Hayden, Iris Grossman, Liat Hayardeny, Rivka Schwartz

P1.213

HLA Genes and InterferonBeta Preparations Influence Risk of Developing Neutralizing Anti-Drug Antibodies in Multiple Sclerosis Katharina Fink, Jenny Link, Malin Lundkvist, Christina Hermanrud, Izaura Lima, Boel Brynedal, Ingrid Kockum, Jan Hillert, Anna FogdellHahn

P1.214

Glatiramer Acetate Treatment Regulates CD44, Receptor for Osteopontin in EAE Mice  Sakhina Begum-Haque, Marc Christy, Kiel Telesford, Yan Wang, Eli Kasper, Azizul Haque, Lloyd Kasper

P1.215

Teriflunomide Does Not Significantly Affect Primary and Memory Antibody Responses to a Viral Antigen in Mice  Andrea Edling, Lisa Woodworth, Adam Stockmann, Tracy Touzjian, Simon Fricker, Bruce Roberts, Johanne Kaplan

Poster Session I

P1.216

ATX-MS-1467, An Immunotolerizing Agent, Halts Disease Progression and Reduces CNS Inflammation in Rodent Models of Multiple Sclerosis  Tammy Dellovade, Stefan Rudin, Alla Zozulya, Blake Tomkinson

P1.217

UVB Light Attenuates the Systemic Immune Response in CNS Autoimmunity  Johanna Breuer, Nicholas Schwab, Tilman Schneider-Hohendorf, Martin Marziniak, Hema Mohan, Urvashi Bhatia, Catharina Groß, Carsten Weishaupt, Sven Meuth, Karin Loser, Heinz Wiendl

P1.218

ONO-4641 (Ceralifimod) Prevents Evoked Potential Deficits in an Animal Model of Multiple Sclerosis Daniel Crawford, Dongzi Yu, Frederic Bernard, Danielle Graham, Ursula Boschert, Tammy Dellovade

P1.219

ONO-4641 (Ceralifimod) Reduces MRI Lesions and Prevents Disease Progression in an Animal Model of Multiple Sclerosis  Shuning Huang, Ji-Kyung Choi, Audrey Gray, Dongzi Yu, Bruce Jenkins, Joseph Mandeville, Guangping Dai, Ursula Boschert, Tammy Dellovade, Danielle Graham

P1.220

Treatment with Anti-mouse CD52 Antibody Is Associated with Preservation of Myelin and Maintenance of Axonal Conduction in the MOG-induced EAE Mouse Model  Jianhua Huang, Petti Pang, Nilesh Pande, Michael Turner, Michael LaMorte, Nathalie Chretien, Carrie Garron, Bruce Roberts, Johanne Kaplan, William Siders

P1.221

Lipoic Acid Reduces Inflammation in a Mouse Focal Cortical Experimental Autoimmune Encephalomyelitis Model.  Priya Chaudhary, Gail Marracci, Danielle Galipeau, Edvinas Pocius, Brooke Morris, Dennis Bourdette

P1.225

Application of the 2010 Macdonald’s Criteria to a Cohort of Patients with Clinically Isolated Spinal Cord Syndromes  Anne Vandendriessche, Helene Zephir, Olivier Outteryck, Damien Fetter, Nicolas Collongues, Nathalie Derache, Gilles Defer, Patrick Vermersch, Jerome De Seze, David Maltete, Bertrand Bourre

P1.226

MRI Phenotypes as Predictors of Clinical Outcomes in Patients with CIS in the Benefit Population  Sven Schippling, Dirk Pleimes, Gilles Edan, Xavier Montalban, Mark Freedman, Hans Hartung, David Miller, Frederik Barkhof, Ernst-Wilhelm Radu, Julia Hermann, Christoph Pohl, Rupert Sandbrink, Roland Martin

P1.227

Randomized Trial of Minocycline for Clinically Isolated Syndrome and Early Single Relapse Multiple Sclerosis: Study Design, Participant Characteristics, and Recruitment Challenges  Luanne Metz, Anthony Traboulsee, David Li, Pierre Duquette, Michael Yeung, Marcelo Kremenchutzky, Galina Vorobeychik, Mark Freedman, Virender Bhan, Gregg Blevins, James Marriott, Francois Grand’Maison, Liesly Lee, Manon Thibault, Misha Eliasziw, V. Wee Yong, Graziela Cerchiaro, Samuel Wiebe, Yan Cheng, Guojun Zhao, Jamie Greenfield, Marites Topor, Andrew Riddehough

P1.228

Predicting Response to Interferon Beta-1B Therapy in Patients with Clinically Isolated Syndrome  MP Sormani, Frederik Barkhof, Ludwig Kappos, Gilles Edan, Mark Freedman, Xavier Montalban, Hans Hartung, David Miller, Julia Hermann, Vivian Lanius, Karola Beckmann, Rupert Sandbrink, Christoph Pohl, Dirk Pleimes

P1.229

Anti-murine CD52 Antibody Treatment Does Not Adversely Affect the Migratory Ability of Immune Cells Evis Havari, Michael Turner, James Dodge, Christopher Treleaven, Lamya Shihabuddin, Bruce Roberts, Johanne Kaplan, William Siders

Longitudinal Mixed-Effect Model Analysis of the Association Between Global and Tissue Specific Brain Atrophy and Lesion Accumulation in Patients with CIS  Mihael Varosanec, Dana Horakova, Jesper Hagemeier, Niels Bergsland, Michaela Tyblova, Zdenek Seidl, Manuela Vaneckova, Jan Krasensky, Michael Dwyer, Eva Havrdova, Robert Zivadinov

P1.223

P1.230

P1.222

Glatiramer Acetate: Shorttime Versus Long-time Administration—A mRNA-Seq Analysis  Marc Kuehl, Paul Hammer, Ronny Amberg, Peter Beyerlein, Juergen Faiss

MS and CNS Inflammatory Disease: Clinically Isolated Syndromes P1.224

An Integrated Model of Risk Factors for Predicting the Early Occurrence of a Second Attack in Patients with Clinically Isolated Syndromes Vittorio Martinelli, Gloria Dalla Costa, Giovanni Di Maggio, Bruno Colombo, Mariaemma Rodegher, Letizia Leocani, Roberto Furlan, Massimo Filippi, Giancarlo Comi

CSF Neurofilament Light Chain Predicts Evolution to MS in Clinically Isolated Syndromes  Stefano Zoccolella, Vita Direnzo, Carla Tortorella, Maddalena Ruggieri, Mariangela Mastrapasqua, Pietro Iaffaldano, Maria Trojano

P1.231

Possible Prognostic Value of Cerebrospinal Fluid in Clinically Isolated Syndrome  Eva Krasulova, Eva Havrdova, David Kemlink, Tomas Uher, Michaela Tyblova, Jana Volna, Katerina Mrazova, Dana Horakova

P1.232

Natural History of Clinically Isolated Syndrome on Conversion to Multiple Sclerosis: A Metaanalysis  Masako Kinoshita, Masako Daifu, Keiko Tanaka, Masami Tanaka

P1.233

Predictors Factora for Risk of Conversion from Clinical Isolated Syndrom to Multiple Sclerosis in a Mixed Brazilian Cohort  Juliana Aurencao, Ana Cristina Wing, Regina Maria Alvarenga, Claudia Cristina Vasconcelos

P1.234

How Much Earlier Can Multiple Sclerosis be Diagnosed Using the McDonald Criteria?  Wallace Brownlee, Josephine Swanton, Olga Ciccarelli, David Miller

Aging, Dementia, and Cognitive and Behavioral Neurology: Basic Science P1.235

PACAP Deficit in Alzheimer’s Disease and Protection Against BetaAmyloid Toxicity  PengCheng Han, Zhiwei Tang, Jun-Xiang Yin, Thomas Beach, Eric Reiman, Jiong Shi

P1.236

Peptidyl-prolyl Isomerase Pin1 as a Potential Target to Protect Synaptic Function in Preclinical Alzheimer’s Disease  Emily Ong, Frances Chow, Yuesong Gong, Carol Lippa

P1.237

Inhibition of Quinone Oxidoreductase 2 Improves Learning in a Mouse Model of Vascular Dementia Jesse Fitzpatrick, Talaignair Venkatraman, Hana Dawson, Haichen Wang, Daniel Laskowitz, Christopher Lascola

Aging, Dementia, and Cognitive and Behavioral Neurology: Biomarkers, Pathology, and Basic Science P1.245

Hereditary Diffuse Leukoencephalopathy with Spheroids (Hdls): Histological Features of Microglia  Mari Tada, Takuya Konno, Masayoshi Tada, Ken-ichi Okazaki, Musashi Arakawa, Kyoko Itoh, Toru Yamamoto, Hideaki Yokoo, Nobuaki Yoshikura, Kenji Ishihara, Yasuko Toyoshima, Osamu Onodera, Masatoyo Nishizawa, Takeshi Ikeuchi, Hitoshi Takahashi, Akiyoshi Kakita

P1.246

The Antibodies Against Gangliosides as Probable Biomarkers in the Serum of Demented Patients Effrosyni Koutsouraki, Eleni Hatzifilippou, Tania Banaki, Vassiliki Costa, Stavros Baloyannis

P1.247

Hippocampal Laminar Distribution of Phospho-Tau Relates to Alzheimer’s Disease and Age of Death  Alon Seifan, James Noble, Jesse Mez, Karen Marder, Lawrence Honig

P1.248

A Beta-2 Adrenergic Agonist Attenuates Cognitive Deficits in Hippocampus of the Mice Following Systemic Inflammation  Hung-Ming Wu, Wan-Yu Huang

P1.249

Abnormal Hypothalamic Leptin Signaling Leads to Early Metabolic Dysfunction in Mice Overexpressing the Amyloid Precursor Protein  Makoto Ishii, Costantino Iadecola

Enhancement of Synaptic Plasticity in Hippocampal Neurons by RNS60, a Novel Therapeutic Containing Charge Stabilized Oxygen-Based Nanostructures.  Avik Roy, Saurabh Khasnavis, Khushbu Modi, Supurna Ghosh, Richard Watson, Kalipada Pahan

P1.239 Amyloid-β Induces NLRP1-

P1.250

P1.238

Dependent Neuronal Pyroptosis in Alzheimer’s Disease  Meng-Shan Tan, Jin-Tai Yu, Teng Jiang, Xi-Chen Zhu, Hui-Fu Wang, Chuan-Dong Jia, Lan Tan

P1.240

Increased Expression of Kv1.3 Channels by Microglia in Alzheimer’s Disease  Srikant Rangaraju, Allan Levey

P1.241

TREM2 Knockdown Exacerbates Aging-related Neuroinflammation and Cognitive Deficiency in SAMP8 Mice  Jiang Teng, Jin-Tai Yu, Lan Tan

P1.242

Direct Actions of Granulocyte-Colony Stimulating Factor on Human Neuronal and Monocytic Cell Lines  Amanda Pennington, Vasyl Sava, Shijie Song, Niketa Patel, Juan SanchezRamos

P1.243 WITHDRAWN P1.244

Pathologic Aggregates of Small Nuclear Ribonucleoproteins (Snrnp) Are Present in Familial Alzheimer’s Disease  Chad Hales, Eric Dammer, Duc Duong, Hong Yi, Marla Gearing, Allan Levey, James Lah, Nicholas Seyfried

Therapeutic Efficacy of D-penicillamine Encapsulated Alginate Nanoparticles in Wistar Rat Model for NonWilsonian Brain Copper Toxicosis  Amit Pal, Rajendra Prasad, Rakesh Vasishta, Babu Thapa

P1.251

Dopamine in Social Valuation: A Genetic and Pharmacological Study  Andrew Kayser, Ignacio Saez, Ming Hsu

P1.252

Activation of Cannabinoid Type 2 Receptors in the Ventral Tegmental Area Modulate Dopamine Excitability via M-Type Potassium Channels.  Brett Larsen, Ming Gao, Jie Wu

P1.253

Insulin-Like Growth Factor-I Receptor Stimulating Activity Is Associated with Dementia  Renée de Bruijn, Joseph Janssen, Michael Brugts, Cornelia van Duijn, Albert Hofman, Peter Koudstaal, Mohammad Ikram

P1.254

De-efferented Motor Cortex Provides a Viable Source of Neural Activity Command Signals for Centrally-Implanted Brain Machine Interfaces  Jose Morales, Karthikeyan Balasubramanian, Kazutaka Takahashi, Nicholas Hatsopoulos

Headache: Basic Science P1.255

Interictal Reduced Cranial Parasympathetic Tone in Cluster Headache  Hilde Karen Ofte, Therese von Hanno, Karl Alstadhaug



Fast, Easy Registration Online  ·  AAN.com/view/AM14

53

Monday April 28



First Authors stand by Posters from 5:00 p.m.–6:30 p.m.



Monday, April 28 P1.256

A Survey of Cluster Headache (CH) Sufferers Using Vitamin D3 as a CH Preventative  Peter Batcheller

P1.257

Optical Imaging of Facial Perfusion in Migraine  Jonas Peterson, Lindsay Hunter, Melissa Cortez, Jeremy Theriot, KC Brennan

P1.258

The CK1δ T44A Mutation Affects Nociceptive Activation of the Trigeminocervical Complex in an In Vivo Model of Migraine  Jan Hoffmann, Margarida Martins-Oliveira, Weera Supronsinchai, Simon Akerman, Michele Lasalandra, Yonglie Zhao, Lina Matsson, Elin Economou-Olsson, Hsien-Yang Lee, Louis Ptacek, Peter Goadsby

P1.259

Characterization of Photosensitivity and Pupil Oscillation Rate in Migraine  Lindsay Hunter, Jonas Peterson, Melissa Cortez, Jeremy Theriot, K.C. Brennan

P1.260

Does Intravenous Hydration Before and After Lumbar Puncture Decrease the Occurrence of Post-Lumbar Puncture Headache?  Nidhi Gupta, Agnieszka Kowalska, Justin Smith, Patricia Coyle

P1.261

Treatment of Withdrawal Headache in Patients with Medication Overuse Headache (MOH): A Randomized, Single-blinded, Placebo Controlled Study  Sabina Cevoli, Giulia Giannini, Valentina Favoni, Elisa Sancisi, Marianna Nicodemo, Stefano Zanigni, Daniela Grimaldi, Giulia Pierangeli, Pietro Cortelli

P1.262

Non-invasive Vagal Nerve Stimulation for the Treatment of Headache Attacks in Patients with Chronic Migraine and Medication-overuse Headache  Innocenzo Rainero, Paola De Martino, Elisa Rubino, Giovanna Vaula, Salvatore Gentile, Lorenzo Pinessi

P1.263

Patient Satisfaction With MAP0004: Results of an Optional Survey During a Long-term Open-label Safety Study  Sheena Aurora, Dawn Buse, Biao Lu, Donald Kellerman, Wade Cooper, Shashidhar Kori

P1.264

Non Invasive Blood Flow Monitoring with Functional Near Infrared Spectroscopy Correlation with Pain Self-Assessment in Subjects Receiving Infusions for Chronic Migrain  David Tabby, Arash Danesh, Ahmad Pourshoghi, Kambiz Pourrezaei

Epilepsy and Clinical Neurophysiology (EEG): Basic Science and ICU Monitoring P1.265 Androgen-mediated

Effects on Ictal Behavior Among Male Rats Is Mediated Through Pregnane Xenobiotic Receptors, which Mediated Neurosteroidognesis  Carolyn Koonce, Jennifer Moore, Swarup Mitra, Cheryl Frye

P1.266

A Novel Mouse Model of X-linked Epilepsy  Ethan Goldberg, Jian Zhou, Douglas Coulter, P. Wang

54

P1.267

Reduction of Tomyson Expression Leads to a Kindling-sensitive Phenotype in a Murine Model of Epilepsy  John Slevin, Seth Batten, Elena Matveeva, Sidney Whiteheart, Thomas Vanaman, Greg Gerhardt

P1.268

Spontaneous Subarachnoid Hemorrhage: Identifying Predictors of Early Outcome Using Continuous EEG. Caitlin Loomis, Scott Kasner, Michael McGarvey, Sarah Schmitt

P1.269

Synchronization Analysis of Depth and Extracranial EEG Seizure Data in Subarachnoid Hemorrhage Ananda-Kriiya Fine, David Albers, J. Michael Schmidt, Deborah Pugin, George Hripcsak, Jan Claassen

P1.270

Evolving Patterns on Prolonged EEG Monitoring in Patients with Therapeutic Hypothermia Post-Cardiac Arrest  Andres Rodriguez-Ruiz, Brandon Foreman, Hyunmi Choi, Stephan Mayer, Jan Claassen, Sachin Agarwal

P1.271

NCSE in Neuro and Medical ICU Patients on Continous EEG Monitoring  Mohamed Tom, Miguel FiolElias

P1.272

Pharmacologically Induced Burst Suppression in Pediatric and Adult Patients—Varying But Predictable Pattern?  Luda Sorin, Brice Jabo, Travis Losey

P1.273

Does the Benefit of Therapeutic Hypothermia in Refractory Status Epilepticus Depend on Seizure Etiology?  Jessica Fesler, Ryan Hakimi, Shrenik Talsania, Emmaculate Fields

P1.274

Role of VEEG Monitoring in Neonates with HIE Undergoing Therapeutic Hypothermia with Correlation of Seizures and Neurodevelopmental Outcome  Misbah Salam, Anjum Hashim, Jasmine Singh

Neural Repair and Neurorehabilitation: Basic Science P1.275

Autologous Bone Marrow Mononuclear Cells for Patients With Motor Neuron Disease—Safety and Feasibility Study  Sankar Gorthi, Pawan Gupta, Satish Kumar, Premkumar Sinha, Harinder Pal Singh

P1.276

Development of a Modified Central Nervous System Extracelluar Matrix with Polylysine.  Eric Marrotte, Naoir Zaher, Yi Zhang, Michael Chopp, Benjamin Buller

P1.277

EEG Characterization of a Cohort of Patients with Disorders of Consciousness: Linking Novel Research Results and Clinical Practice. Peter Forgacs, Mary Conte, Jonathan Victor, Nicholas Schiff

P1.278

Gene Therapy with Neurotrophic Factors Improves Recovery After Sciatic Nerve Injury in Mice Mica Glat, Felix Benninger, Tali Ben-Zur, Yael Barhum, Israel Steiner, David Yaffe, Daniel Offen

3:00 p.m.–6:30 p.m. P1.279

Receptor for AGE (RAGE) Expressed in Macrophages and Neurons Regulates Peripheral Nerve Repair After Injury  Lingling Rong, Shifang Yan, Arthur Hays, Clifton Gooch, Ann Marie Schmidt

P1.280

Evaluation of the Performance of a Brain-Computer Interface Under Two Biofeedback Paradigms  Brian Appavu, Jenessa Lancaster, Remy Wahnoun, P. David Adelson

P1.281

Evoked and Oscillatory Activity Dynamics in Vegetative State  Gonzalo Rivera

P1.282

Functional Organization of the Human Auditory Fields: Activation of Auditory Cortex in a Patient with Auditory Agnosia from Traumatic Injury of the Inferior Colliculus, and the Effects of Transcranial Direct Current Stimulation  Robert Rafal, Oren Poliva, Patricia Bestelmeyer, Nicholas Davis

P1.283

The Therapeutic Capability of Slow-release 4-Aminopyridine for the Treatment of Peripheral Nerve Crush Injury  Kuang-Ching Tseng, John Elfar

P1.284

Predictors of Change in Quality of Life in Patients with Focal Neurological Damage Following an Outpatient Cognitive Rehabilitation Program  Galeno Rojas, Adriana Leis, Natalia Ciufia, Gastón Saux, Carolina Feldberg, Fernando Caceres, Ignacio Demey

History of Neurology P1.285

General Wood: Physician, Rough Rider, Ambassador, Presidential Candidate, Patient.  Mariza Daras, E. Massey

P1.286

Silas Weir Mitchell on Epilepsy Therapy in the Late 19th and Early 20th Centuries  David Burkholder, Christopher Boes

P1.287

Historical Articles in the Neurology® Journal as a Tool to Raise Awareness about the Importance of Bedside Medicine  Raghav Govindarajan, John Morren, Efrain Salgado

P1.288

Philadelphia Odd Couple— Silas Weir Mitchell—NeurologistNovelist-Poet and Phillips Brooks— Brahmin Prophet—Sons of 19th Century Rittenhouse Square  Benjamin Brooks

P1.289

Early Historical and Ethnographic Descriptions of the Properties of Curare in the Spaniards Chronicle.  Carolina Vazquez, Francisco Carod

P1.290

Charcot-Marie-Tooth Disease (CMT): Historical Perspectives and Evolution  Mohamed Kazamel, Christopher Boes

P1.291

History of Anti-inflammatories in Headache: Acetanilid, Antipyrin, Phenacetin and Salicyclic Acid Rosen Noah, Dennis Thornton

P1.292

Jesuit Bark and Horseback Rides: Thomas Jefferson’s “Fits” as a Window into 18th Century Headache Care  Matthew Luedke, E. Massey

2O14 Scientific Abstract Listing and Annual Meeting Information

P1.293

Neurology, Volume 1, 1951  William Campbell

P1.294

Robert E. Lee’s Last Stand: His Dying Words and the Stroke That Killed Him.  Andrew Southerland

P1.295

Introduction of the Pulfrich Phenomenon into Clinical Neurology  James Lanska, Douglas Lanska, Bernd Remler

P1.296

Food for Thought: A Serving of Food-Inspired Eponyms in Neurologic Practice  Shin Beh, Teresa Frohman, Amy Conger, Darrel Conger, Peter Calabresi, Laura Balcer, David Zee, Elliot Frohman

P1.297

125 Hysterical Years—the Contribution of Charcot’s.  Francisco Branco Germiniani, Renato Munhoz, Luciano De Paola, Helio Teive

P1.298

Social Network Analysis of Presidents in Neurology Professional Organizations Since 1948  Amar Dhand, Jordan Harp, Stephen Borgatti

P1.299

Russell N. DeJong: A Seminal Figure in American Neurology William Campbell

P1.300

History of Neurology in Bangladesh  Nasheed Jamal, Shrikant Mishra, Bhavesh Trikamji

P1.301

Rejected Applications: An Early American Academy of Neurology Struggles to Define its Membership Elan Louis

P1.302

Description of the Pulfrich Effect  James Lanska, Douglas Lanska, Bernd Remler

P1.303

Gerstmann, Sträussler, Scheinker Disease: A Famous Syndrome From an Infamous Period in History  Lawrence Zeidman, Matthias Ziller, Michael Shevell

P1.304

Zinc-induced Myelopathy Among Smelter Workers in Upper Silesia During the Late 19th Century Douglas Lanska, Bernd Remler

P1.305

The Visible Brain: Computed Tomography’s Impact on Neurological Practice  Charlene Ong

P1.306

Meta-analyses to Investigate Gene-environment Interactions in Neuroepidemiology  Ingrid van der Mei, Petr Otahal, Steve Simpson, Bruce Taylor, Tania Winzenberg

Neurology Education: Graduate Medical Education P1.307

Simulation Boot Camp for Neurology Residents: A Unique Experience From a Training Perspective  Nauman Tariq, Muna Irfan, Jeffrey Willging, Elisabeth Hurliman, Fitzgerald Lisa, Danielle Hart, Carly Dolan, Ezgi Tiryaki

P1.308

Educating Future Clinical Research Investigators: An 8-Week Clinical Research Education Course for Neurology Residents  Jeanie McGee

Poster Session I

P1.309

Can Young European Neurologists Comfortably Manage Patients with Traumatic Brain, Spine or Nerve Injuries (Tbi)?  Martin Rakusa, Sofya Gak, Yuri Alekseenko, Edvard Ehler, Dafin Muresanu, Josef Opara, Pieter Vos

P1.310

Positive Deviance for Improvement of Efficiency and Resident Satisfaction in Neurology Continuity Clinic  Julio Rojas -Martinez, Kartavya Sharma, Steven Vernino, Pravin Khemani

P1.320

The Rolling Continuity Clinic: A Flexible Scheduling Paradigm  Kristin Scott, Warren Carrigan, Heidi Woessner, David Capobianco, Devon Rubin, Elliot Dimberg

P1.321

Implementation of Active Learning into the Pre-Clinical Neurology Undergraduate Medical Curriculum John Pula, John Nixon, Meenakshy Aiyer, Jorge Kattah

P1.322

Preparing Child Neurology Residents for Inpatient Adult Neurology  Emily Johnson, Tracey Milligan

Heterogeneity in Neurological Education and Care in Asian and Oceanian Region  Man Mohan Mehndiratta, Prachi Mehndiratta, Natasha Gulati, Mohammad Wasay

P1.312

P1.323

P1.311

Clinical Neuroscience Podcasts for Family Medicine, Internal Medicine, and Neurology Residents: A Needs Assessment Study  Tyson Brust, Michael Yeung

P1.313

Trends in American Board of Psychiatry and Neurology Specialties and Neurologic Subspecialties  Larry Faulkner, Dorthea Juul

P1.314

Quantification of Postural Stability Using Accelerometer and Gyroscopic Measures from the iPad Susan Linder, Joshua Hirsch, Mandy Koop, David Schindler, Anil Thota, Jay Alberts

P1.315

Effectiveness of Pairing Weekly Reading Assignments and Quiz with Audience Response System for Neurology Resident Learning Rashedul Hasan, Jennifer Fry, John DeToledo, Jongyeol Kim

P1.316

Standardized Evaluation of Didactic Conference Content in Neurology Residency: A New Approach Arthie Jeyakumar, Constantine Farmakidis

P1.317

Unsuccessful Lumbar Puncture: Blame it on the Patient, Not the Operator  Cory Edwards, Enrique Leira, Pedro Gonzalez-Alegre

P1.318

Changing Medical Student Perceptions of Dementia: An Arts-centered Experience  Hannah Roberts, James Noble

Neurology Education: Graduate Medical Education/ Undergraduate Medical Education P1.319

Computer Generated Checklist Significantly Improves Differential Diagnosis in Neurologic Disease Over Simple Recall  Pasquale Finelli, Andrew McCabe

High-Fidelity Simulation Versus Traditional Didactic Techniques for Teaching Neurological Emergencies to Neurology Residents: A Feasibility Study.  Sachin Agarwal, Neha Dangayach, Priyank Patel, Ashley Roque, Melissa Cappaert, Dennis Fowler, Jan Claassen, Stephan Mayer

P1.324

The One-Year Clinician Educator Curriculum: Neurology Residents as Teachers  Veronica Santini, Anna Hohler

P1.325

Teaching Ophthalmoscopy to Medical Students (TOTeMS) II: A One-Year Retention Study  Devin Mackay, Philip Garza, Beau Bruce, Samuel Bidot, Linda Kelly, Emily Graubart, Nancy Newman, Valerie Biousse

P1.326

An Interactive Mobile Curriculum for Teaching the HypothesisDriven Neurological Examination Dylan Alegria, Vanja Douglas, Chandler Mayfield, Christy Boscardin, S. Josephson, Daniel Lowenstein, Susannah Cornes

P1.327

Neurologists Versus Emergency Physicians: Reliability of a Neurological Script Concordance Test in a Multi-Centre, Cross-disciplinary Setting  Derek Soon, Nigel Tan, Derek Heng, Liqi Chiu, Malcolm Madhevan, Charmaine Manauis, Dong Haur Phua, Gominda Ponnamperuma, Kevin Tan

P1.328

Methodology for Delivering Feedback to Neurology House Staff on Communication Skills Using AIDET (Acknowledge, Introduce, Duration, Explanation, Thank you)  Austin Katona, Elisabeth Kunkel, Jasmine Arfaa, Stephen Weinstein, Christopher Skidmore

P1.329

Zygosity Detection by Next Generation Sequencing in a Clinical Laboratory  Zhenyuan Wang, Christine DiVincenzo, Christopher Elzinga, Martin Bazinet, Sat Dev Batish, Malgorzata Jaremko, Joseph Higgins

Neurology Education and Methodology P1.330

Chasing Veins in Vain? The History of Vessel-Based Aetiological Theories and Pathological Studies in Multiple Sclerosis  Aravind Ganesh, Dawn Pearson, Frank Stahnisch

P1.331

National Survey of UK Medical Students on the Perception of Neurology  Julia Pakpoor, Adam Handel, Giulio Disanto, Richard Davenport, Gavin Giovannoni, Sreeram Ramagopalan

P1.332

Comparison of American Academy of Neurology’s online patient Education Materials to Other Common Internet Sources.  Anjali Dagar, Vineet Punia, Nitin Agarwal, Wenzhuan He, Machteld Hillen

P1.333

Is Formal Faculty Assessment of Bedside Skills Feasible for 3rd Year Medical Students on the Neurology Clerkship?  Robert Thompson-Stone, Erika Wexler, Jonathan Mink, Ralph Jozefowicz

P1.334

Network for Excellence in Neuroscience Clinical Trials, NeuroNEXT: Increasing Efficiency in Clinical Trial Management  Marianne Kearney, Dixie Ecklund, Michael Bosch, Brenda Thornell, Dawn McNeil, Walter Koroshetz, Petra Kaufmann, Christopher Coffey, Merit Cudkowicz

P1.335

Use of Mentored Peer Review of Standardized Manuscripts as an Educational Tool for Neurology Residents  Roy Strowd, Victoria Wong, Rebeca Aragon-Garcia, Yeseon Moon, Blair Ford, Sheryl Haut, Joseph Kass, Zachary London, Mary Mays, Tracey Milligan, Raymond Price, Patrick Reynolds, David Spencer, Mitchell Elkind

P1.336

Scheduled Faculty Modeling of Bedside Skills for 3rd Year Medical Students on the Neurology Clerkship  Robert Thompson-Stone, Trenton Tollefson, Ronald Epstein, Ralph Jozefowicz, Jonathan Mink

P1.337

Parallel Sequencing of 26 Genes Responsible for Metabolic Myopathy and Rhabdomyolysis  Xia Tian, Jing Wang, Margherita Milone, Yanming Feng, Victor Zhang, Lee-jun Wong

P1.338

Comprehensive Diagnosis of Congenital Neuromuscular Disorders by Next Generation Sequencing of 236 Genes with Deep Coverage  Xia Tian, Wen-Chen Liang, Yanming Feng, Jing Wang, Victor Zhang, Lee-jun Wong, Yuh-Jyh Jong

P1.339

Feasibility of Developing a Neurophysiologic Assessment of Concussion  Nolan Williams, Jan Enabore, Emily Williams, Donna Roberts, Jonathan Edwards

P1.340

ALS Clinical Research Learning Institutes: Empowering PALS to be Research Ambassadors Richard Bedlack, Merit Cudkowicz

Child Neurology and Developmental Neurology I P1.341

Continuous Intravenous Valproic Acid as an Abortive Therapy for Pediatric Migraine  Muhammad Zafar, Aaron Cook, Alejandra Stewart, Robert Baumann

P1.342

Fatal Outcome of Status Epilepticus, Hyperthermia, Rhabdomyolysis, Multi-Organ Failure, and Cerebral Edema After 25I-NBOMe Ingestion  Yoshie Umemura, Thomas Andrew, Valerie Jacobs, Andrew Giustini, Lionel Lewis, Jennifer Hanowell, James Filiano

P1.343

Whole Genome Sequencing Identifies a Novel Occludin Mutation in Microcephaly with Band-like Calcification and Polymicrogyria that Extends the Phenotypic Spectrum  Mahmoud Osman, Elizabeth Ross, Alice Abdel Aleem, Khalid Ibrahim, Ben-Omran Tawfeg, Hussein Kamel

P1.344

A Prenatal Presentation of Severe Microcephaly and Brain Anomolies in a Patient with Novel Compound Heterozygous Mutations in the STIL Gene  Harvey Bennett, Amy Presti, Darius Adams, Jose Rios

P1.345

Sleep Abnormalities in Children with Dravet Syndrome Radhika Dhamija, Maia Erickson, Erik St Louis, Suresh Kotagal

P1.346

Utility of Continuous EEG Monitoring in Pediatric Man in the Barrel Syndrome: A Case Report Jessica Goldstein, Bilal Zonjy, Ingrid Tuxhorn, Barbara Bangert, Nancy Bass

P1.347

Prediction of Future Seizures in Neonates Who Received Selective Head Cooling for HIE  Tiffani McDonough, Juliann Paolicchi, Nikkan Das, Murray Engel, Jeffrey Perlman, Zachary Grinspan

P1.348

Value of Routine EEG in Autistic Patients with Stereotypic Behavioral Movements  Ankit Nayyar, Neha Mirchandani, Rebecca Spiegel

2015 Education Course Proposal Process 2015 Annual Meeting: Washington, DC

The AAN invites you to submit an Education Program suggestion for May 16, 2014. To submit your proposal, please visit the 67th Annual Meeting. Proposals for new programs are due by AAN.com/view/SearchAM.



Fast, Easy Registration Online  ·  AAN.com/view/AM14 55

Monday April 28



First Authors stand by Posters from 5:00 p.m.–6:30 p.m.



Tuesday, April 29 P2  Poster Session II First Authors stand by Posters from 7:30 a.m.–9:00 a.m.

7:30 a.m.–11:00 a.m.

Poster Discussion Session: Movement Disorders II Utilizing a guided tour format, topic experts will lead attendees around the ten posters in the poster discussion session and facilitate questions with poster authors during the 90-minute author stand-by time.

P2.001 Cortico-striatal-thalamic

Network Functional Connectivity in Hemiparkinsonism  Francesca Caso, Federica Agosta, Iva Stankovic, Alberto Inuggi, Igor Petrovic, Marina Svetel, Giancarlo Comi, Vladimir Kostic, Massimo Filippi

P2.002

Neuroanatomical Changes in Parkinson’s Disease: Neuroimaging Evaluation of Pedunculopontine Nucleus  Fang Ba, Marguerite Wieler, Myrlene Gee, Wayne Martin

P2.003 (18)FDG-PET Scan as a

Predictive Marker of Postoperative Apathy After Subthalamic Nucleus Deep Brain Stimulation in Parkinson Disease. Aude Gesquiere-Dando, Eric Guedj, Tatiana Witjas, Frederique Fluchere, Marie Delfini, Laura Mundler, Jean Azulay, Alexandre Eusebio

P2.004

Differential Patterns of White Matter Degradation in Relation to Cognitive and Motor Deficits in Parkinson’s Disease  Yu Zhang, Norbert Schuff

P2.005

Brain Functional Connectomics in Early Parkinson’s Disease Sebastiano Galantucci, Federica Agosta, Iva Stankovic, Alessandro Meani, Igor Petrovic, Marina Svetel, Giancarlo Comi, Vladimir Kostic, Massimo Filippi

P2.006

Corpus Callosum Damage and Motor Function in Parkinson’s Disease  Sebastiano Galantucci, Federica Agosta, Iva Stankovic, Igor Petrovic, Tanya Stojkovic, Giancarlo Comi, Vladimir Kostic, Massimo Filippi

P2.007

Interval Changes of ForebrainCortical Versus Brainstem-thalamic Cholinergic Integrity in Parkinson Disease Progression  Nicolaas Bohnen, Martijn Muller, Vikas Kotagal, Kirk Frey, Roger Albin

P2.008 Dopaminergic Changes in

Corticostriatal Brain Activity and Causal Interactions during Working Memory in Parkinson’s Disease.  Kathleen Poston, Sophie YorkWilliams, Weidong Cai, David Everling, Matthew Cruadhlaoich, Michelle Fenesy, Vinod Menon

P2.009

Striatal and Extrastriatal Dopamine Transporter Levels Relate to Cognition in Lewy Body Diseases Stephen Gomperts, Marta Marquie Sayagues, Joseph Locascio, Dorene Rentz, Alex Becker, Trey Hedden, Keith Johnson, John Growdon

P2.010

Ascending Progression of Grey Matter Atrophy in Parkinson’s Disease  Maria Cristina Arci Santos, Lidiane Campos, Rachel Guimaraes, Camila Piccinin, Paula Azevedo, Luiza Piovesana, Brunno Campos, Augusto Amato-Filho, Fernando Cendes, Anelyssa D’Abreu

NEW! e  Poster Session: Cerebrovascular Disease and Interventional Neurology I The ePoster session will feature a selection of posters to be presented digitally, rather than in the traditional format. Authors will be able to take advantage of the format to highlight compelling visual features such as images and videos. See poster map on page 47 for location.

P2.011

PFO Closure for Stroke Prevention. A Brief Meta-analysis Leila Doldan, Manuel Latini, Jeffrey Saver

P2.012

Stroke and Etonogestrel/ Ethinyl Estradiol Ring (NuvaRing): Clinical, Radiological, and Prognostic Features.  Pirouz Piran, Clotilde Balucani, Brian Tark, Zachary Adler, Steven Levine

P2.013

Intracranial Arterial Dissection  Daiana Dossi, Mauricio Farez, Julieta Arena, Virginia Pujol Lereis, Guillermo Povedano, Sebastian Ameriso

Movement Disorders: Parkinson’s Disease Genetics P2.021 Neuropsychological

Performance in LRRK2 G2019S Carriers with Parkinson’s Disease  Roy Alcalay, Helen Mejia Santana, Anat Mirelman, Rachel Saunders-Pullman, Deborah Raymond, Laurie Ozelius, Avi Orr-Urtreger, Lorraine Clark, Nir Giladi, Susan Bressman, Karen Marder

P2.014

Identifying Barriers in Acute Stroke Therapy in Argentina. ARENAS Registry  Ana Atallah, Osvaldo Fustinoni, Maria Zurru, Ricardo Beigelman, Juan Cirio, Sebastian Ameriso, Guillermo Burry

P2.015

Comparison of Large Vessel Stroke Patient Outcomes Before and After Initiation of On-site Endovascular Stroke Treatment Services  Yamin Shwe, Santiago Ortega-Gutierrez, Amy Walker, Irene Boniece, Alejandro Berenstein, Johanna Fifi

P2.022

Phenotypic Spectrum of SNCA G209A Mutation Carriers for Familial Parkinson’s Disease in Greece  Dimitra Papadimitriou, Roubina Antonelou, Maria Stamelou, Maria Bozi, Matina Maniati, Nikolaos Papagiannakis, Sevasti Bostantjopoulou, Athanassios Leonardos, Sokratis Papageorgiou, Georgios Hadjigeorgiou, Eleni Kapaki, George Tagaris, Alexandros Papadimitriou, Aglaia Athanassiadou, Leonidas Stefanis

P2.023

Clinical and Neuroimaging Features of a Patient with Early-onset Parkinson’s Disease with Dementia Carrying SNCA p.G51D Mutation Takayoshi Tokutake, Atsushi Ishikawa, Nahoko Yoshimura, Akinori Miyashita, Ryozo Kuwano, Masatoyo Nishizawa, Takeshi Ikeuchi

56

P2.016

The Utilization of Forced Aerobic Exercise to Augment the Recovery of Motor Function Following Stroke: A Randomized Clinical Trial  Susan Linder, Anson Rosenfeldt, Amanda Penko, Jay Alberts

P2.018

P2.017

Prediction of Ischemic Brain Penumbra Using Acute MR Information and Inelastic Collision Model  Hassan BagherEbadian, Panayiotis Mitsias, James Ewing, Hamid Soltanian-Zadeh

P2.019 WITHDRAWN

P2.024 Neuropsychiatric

P2.026

Features of GBA-Associated Parkinson Disease  Matthew Swan, Robert Ortega, Matthew Barrett, Jeannie Soto-Valencia, Sarah Boschung, Andres Deik Acosta Madiedo, Harini Sarva, Jose Cabassa, Brooke Johannes, Deborah Raymond, Joan Miravite, William Severt, Rivka Sachdev, Vicki Shanker, Susan Bressman, Rachel Saunders-Pullman

P2.025

Interest in Genetic Testing in Ashkenazi Jewish Parkinson Disease Patients and Their Unaffected Relatives  Manisha Gupte, Roy Alcalay, Helen Mejia Santana, Deborah Raymond, Rachel Saunders-Pullman, Anat Mirelman, Lorraine Clark, Laurie Ozelius, Avi OrrUrtreger, Nir Giladi, Susan Bressman, Karen Marder

2O14 Scientific Abstract Listing and Annual Meeting Information

Prognostic Value of CT Angiography in the Hyperacute Phase of Middle Cerebral Artery Stroke. Pigreti Santiago, Maria Zurru, Ariel Luzzi, Laura Brescacin, Claudia Alonzo, Luis Camera, Gabriel Waisman, Edgardo Cristiano

P2.020 WITHDRAWN

Cognitive Signatures of Parkinson’s Disease and Glucocerebrosidase (GBA) Mutation  Masud Husain, Nahid Zokaei, Alisdair McNeil, Christos Proukakis, Michelle Beavan, Paul Jarman, Prasad Korlipara, Derralyn Hughes, Atul Mehta, Michele Hu, Anthony Schapira

P2.027

Non-motor Symptoms in Genetic Forms of Parkinson Disease EvaJuliane Vollstedt, Christine Klein, Meike Kasten

Poster Session II Marrying Direct to Consumer Genetic Data with Remote Phenotypic Assessments in Parkinson Disease E. Ray Dorsey, Kristin Darwin, Samara Mohammed, Sean Donohue, Alyssa Tethal, Meredith Achey, Susan Ward, Elaine Caughey, Nicholas Eriksson, Emily Conley, Bernard Ravina

P2.029

Exploring Genetic Influences on Variation in the Phenotypic Expression of Parkinson’s Disease.  Naveed Malek, Sarah Marrinan, Nin Bajaj, Roger Barker, Yoav Ben-Shlomo, Catherine Bresner, David Burn, Thomas Foltynie, Huw Morris, Nigel Williams, Nicholas, W Wood, Donald Grosset

Movement Disorders: Friedreich’s and Other Inherited Ataxias P2.030 Predictive Equations to

Muscle Mass Volume in Patients with Spinocerebellar Ataxia  Christiane Leite, Darla Macedo, Maria Schieferdecker, Regina Vilela, Helio Teive, Adriana Moro

P2.031

Clinical and Genetic Profile of Brazilian Patients with Late-Onset Friedreich’s Ataxia  Alberto Martinez, Conrado Borges, Cynthia Bonilha Da Silva, Adriana Moro, Thiago Rezende, Mariana Moscovich, Renato Munhoz, Walter Arruda, Simone Karuta, Anelyssa D’Abreu, Iscia Lopes-Cendes, Marcondes Franca, Jr., Helio Teive

P2.032

Disruption of Binaural Hearing in Spinocerebellar Ataxia Type 13 Michael Waters, Harry Nick, S Subramony, Joel Advincula, Raymond Rosales, Lillian Lee, Tetsuo Ashizawa, Middlebrooks John

P2.033

‘Pseudo-dominant’ Inheritance in Friedreich’s Ataxia: Clinical and Genetic Study of a Brazilian Family  Adriana Moro, Alberto Martinez, Mariana Moscovich, Simone Karuta, Renato Munhoz, Walter Arruda, Salmo Raskin, Francisco Germiniani, Helio Teive

P2.034

Neurodevelopmental Defects in Spinocerebellar Ataxia Type 13 Linked to the EGF-R Signaling Pathway Swati Khare, Donya Salmasinia, Daniela Arbelaez, Jerelyn Nick, Diego Rincon-Limas, Harry Nick, Pedro Fernandez-Funez, Michael Waters

P2.035

When Should We Test Patients with Familial Ataxias for SCA31?  Agessandro Abrahao Junior, Jose Pedroso, Kinya Ishikawa, Salmo Raskin, Paulo Sgobbi de Souza, Hidehiro Mizusawa, Orlando Barsottini

P2.036

Substantia Nigra Echogenicity Is Correlated with Nigrostriatal Impairment in Machado-Joseph Disease  José Luiz Pedroso, Orlando Barsottini

P2.037

Children with Friedreich Ataxia Undergoing Spinal Fusion Are at Risk for Arrhythmias  Kimberly Lin, David Lynch, John Flynn, Joseph Rossano

P2.038

Assessing the Feasibility of Quantitative Gait Analysis as an Outcome Measure for Clinical Trials in Spinocerebellar Ataxias  Hokuto Morita, Heather Vincent, Nawaz Hack, Bryan Conrad, Tetsuo Ashizawa, S Subramony, Guangbin Xia

Movement Disorders: Dystonia P2.039

The Phenomenology and Natural History of Idiopathic Lower Cranial Dystonia  Pichet Termsarasab, Steven Frucht

P2.040

Clinical and Genetic Evaluation for DYT1 and DYT6 Genes in Brazilian Patients with Cervical Dystonia Carlos Camargo, Sarah Camargos, Salmo Raskin, Francisco Cardoso, Helio Teive

P2.041

Familial and Sporadic Cases of Cervical Dystonia in 88 Patients Carlos Camargo, Sarah Camargos, Nilson Becker, Renato Munhoz, Salmo Raskin, Francisco Cardoso, Helio Teive

P2.042

Tricks to Treatments: Sensory Tricks in Dystonia  Vesper Ramos, Barbara Karp, Mark Hallett

P2.043

The Evaluation of Environmental Factors in the Disease Penetrance of Cervical Dystonia Anna Molloy, Okka Kimmich, Laura Williams, Fiona Molloy, Helena Moore, Daniel Healy, Timothy Lynch, Cathal Walsh, Richard Reilly, Sean O’Riordan, Michael Hutchinson

P2.044

Is Geste Antagoniste a Predictive Factor of Effectiveness of Botulinum Toxin A Treatment? Martin Bares, Rastislav Sumec, Pavel Filip

P2.045

Brain Structural Changes in Primary Focal Dystonia  Lidia Sarro, Francesca Caso, Federica Agosta, Sebastiano Galantucci, Aleksandra Tomic, Marina Svetel, Nikola Kresojevic, Giancarlo Comi, Vladimir Kostic, Massimo Filippi

P2.046

Alleviating Maneuvers (Sensory Tricks) in Cervical Dystonia  Neepa Patel, John Hanfelt, Laura Marsh, Joseph Jankovic

P2.047

Sensory Tricks Reverse Intracortical Facilitation Changes in Cervical Dystonia. A Transcranial Magnetic Stimulation Study  Stefano Amadio, Elise Houdayer, Francesca Bianchi, Habtom Tesfaghebriel Tekle, Ivan Urban, Calogera Butera, Roberta Guerriero, Marco Cursi, Letizia Leocani, Giancarlo Comi, Ubaldo Del Carro

Movement Disorders: Co-morbidities and Novel Care Models P2.048 Telehealth in the Parkinson’s

Disease Subspecialty Clinic: The Key to the Patient-Centered Medical Home Meredith Spindler, Eileen Hummel, Stephanie Pawlowski, Daniel Weintraub, Steven Marcus, Margaret Stineman, James Morley, John Duda, Jayne Wilkinson

P2.049

Proof of Concept for Operation House Call for Underserved Parkinson’s Disease Patients  Nawaz Hack, Umer Akbar, Amanda Eilers, Valerie RundleGonzalez, Daniel Martinez-Ramirez, Hokuto Morita, Irene Malaty, Michael Okun

P2.050

Caregiver Tele-support Group for Parkinson’s Disease: A Pilot Study  Shital Shah, Gretchen Glenn, Eileen Hummel, Jane Hamilton, Rebecca Martine, Jayne Wilkinson



P2.051

Zung Self Rating Depression Scale in Parkinson’s Disease: A Validity Study in Veterans  Aliya Sarwar, Max Hirshkowitz

P2.052

MDS-Sponsored Scale Translation Program: Process, Format, and Clinimetric Testing Plan for the MDSUPDRS and UDysRS  Christopher Goetz, Glenn Stebbins, Lu Wang, Nancy LaPelle, Sheng Luo, Barbara Tilley

P2.053

Prevalence of Non-motor Symptoms in Parkinson’s Disease: A Systematic Review with MetaAnalysis  Michele Tagliati, Kallol Chaudhuri, Gennaro Pagano

P2.054

The Relationship Between Vitamin D Concentrations and Leg Strength in Persons with Parkinson’s  Amie Peterson, Brenna Lobb, Charles Murchison, Joseph Quinn

P2.055

Statin Use, Apolipoprotein A1, and Parkinson’s Disease  Yosef Berlyand, Roy Alcalay, Christine Swanson, Stanley Fahn, Cheryl Waters, Oren Levy, Stephen Schwartz, Alice Chen-Plotkin

P2.056

Obesity Associates with Impaired Quality of Life in Parkinson Disease  Vikas Kotagal, Martijn Muller, Nicolaas Bohnen

P2.057

Comorbidities and Causes of Death in a Cohort Of 205 Patients with Parkinsonism  Mariana Moscovich, Gabriela Boschetti, Adriana Moro, Helio Teive, Renato Munhoz

Neuropathy: Genetics and Outcomes P2.058

The Allelic Spectrum of Charcot-Marie-Tooth Disease in Over 17,000 Individuals with Neuropathy  Joseph Higgins

P2.059

Can Glucose Disorders Affect the Severity of CMT1A Neuropathy?  Juliana Algemiro, Rita De Cassia Leal, Charles Lourenco, Waldemar Algemiro, Vanessa Marques, Wilson Marques

P2.060

Whole Exome Sequencing Identified a Novel Mutation in PMCA4 Gene for Autosomal Dominant Familial Spastic Paraplegia (ADFSP) in a Chinese Family  Wing Lok Ho, Shirley Pang, Miaoxin Li, Michelle Kung, Pak-Chung Sham, Shu Leong Ho

P2.061

Early- Versus Late-onset Phenotypes of Transthyretin Val30Met Familial Amyloid Polyneuropathy Valeria Salutto, Valeria Alvarez, Diego Beratti, Fabio Barroso, Claudio Mazia

P2.062

Wide Spectrum of Neuropathy in Homozygous and Heterozygous Novel Frameshift MPZ Mutation in a Tunisian Family  Youssef Sidhom, Imen Kacem, Yousser Hizem, Mouna Ben Djebara, Amina Gargouri, Eric Leguern, Riadh Gouider

P2.063

T118M PMP22 as a Modifier for Hereditary Neuropathy with Liability to Pressure Palsy (HNPP)  Nivedita Jerath, Tiffany Grider, Andrea Swenson, Michael Shy

P2.064 Adrenomyeloneuropathy

Diagnosed in a Young Female with Spastic Paraparesis after Full Exome Sequencing  Tania Garcia, A Ordoñez Ugalde, Beatriz Quintans, Maria Jesus Sobrido, M. C. Amigo, Eva Costa Arpin, Julio Pardo-Fernandez

P2.065

Detection of Copy Number Variation (CNV) in Patients with CMT1A by SNP-Allelotyping  Brett Parker, Ryan Alexander, Nathalie Schnetz-Boutaud, Xingyao Wu, Michael Shy, Jun Li

P2.066

CMT2A2 Associated with Novel MFN2 Gene Double Missense Mutations in CIS  Haatem Reda, Gyorgy Abel, Jayashri Srinivasan

P2.067

Health-related Quality of Life by SF-36 in Patients with HNPP compared to Those with CMT1A  Tiffany Grider, David Cuthbertson, Shawna Feely, Michael Shy

ALS: Genetics and Outcomes P2.068

Madras Pattern Motor Neuron Disease Caused by a Novel Mutation in the UBQLN2 Gene  Hacer Durmus, Aslihan Ozoguz, Ozgun Uyan, Feza Deymeer, Piraye Serdaroglu, Nazli Basak, Yesim Parman

P2.069

Regional Variation of Causative ALS Genes  Summer Gibson, Karla Figueroa, Linh Huynh, Mark Bromberg, Stefan Pulst

P2.070

Meta-Analysis of ALS Risk for Ataxin-2 (SCA2) CAG Repeat Alleles  Annalese Neuenschwander, Khanh Thai, Karla Figueroa, Stefan Pulst

P2.071

Use of Veterans Specific Activity Questionnaire (VSAQ) to Estimate Exercise Tolerance in Ambulatory Amyotrophic Lateral Sclerosis (ambALS) Patients  Mohammed Sanjak, Jasmin Headen, Kendall Barrett, Scott Holsten, Velma Langford, Elena Bravver, William Bockenek, Urvi Desai, J Scott Story, Scott C Lindblom, Thomas Paccico, Benjamin Brooks

P2.072

Amyotrophic Lateral Sclerosis (ALS) Estimates from National Databases in the United States—2001-2010  Marchelle Sanchez, Paul Mehta, Wendy Kaye, Vinicius Antao, D. Kevin Horton

P2.073

Using Mortality Data as a Component of Amyotrophic Lateral Sclerosis (ALS) Surveillance in New Jersey (NJ)  Heather Jordan, Jerald Fagliano, Daniel Lefkowitz, Lindsay Rechtman, Wendy Kaye

P2.074

Mortality and Cause of Death Among Confirmed ALS Cases, Los Angeles and San Francisco Bay Area Metropolitan ALS Surveillance Project 2009-2011 Susan Paulukonis, Jhaqueline Valle, Natalie Collins, Eric Roberts, Paul English, Wendy Kaye

P2.075

Predictors of Early Mortality in Patients with Amyotrophic Lateral Sclerosis Undergoing Elective Percutaneous Endoscopic Gastrostomy or Jejunostomy Placement: The Mayo Clinic Experience  Sherri Braksick, Lyell Jones, Jayawant Mandrekar, Sara Hocker

Fast, Easy Registration Online  ·  AAN.com/view/AM14

57

Tuesday April 29

P2.028



Tuesday, April 29 P2.076

Predictors of Outcome in Amyotrophic Lateral Sclerosis  Elena Ratti, James Berry, Nazem Atassi, Amy Shui, Douglas Hayden, David Schoenfeld, Hong Yu, Robin Conwit, Jeremy Shefner, Merit Cudkowicz

P2.077

Investigating the Relationship Between Length of Stay in Hospice Care and Rates of Change on ALS Functional Rating Scale-Revised and FVC in Patients with Amyotrophic Lateral Sclerosis Grace Shen, Lauren Elman, Nabila Dahodwala, Kelly Almasy, Mary Kelley, Leo McCluskey

Neuromuscular Junction P2.078

Incidence, Risk Factors and Clinical Features of Myasthenic Crises Chi Yan Lee

P2.079

Genetic Predisposition to MuSK -Positive Myasthenia Gravis in Patients from Argentina  Claudio Mazia, Marcelo Francisco Rugiero, Valeria Salutto, Pablo Galarza, Flavia Canitano, Adrian Perusco

P2.080 Is the Decremental Pattern

in Lambert-Eaton Myasthenic Syndrome Different from That in Myasthenia Gravis?  Donald Sanders, Lucy Cao, Janice Massey, Vern Juel, Lisa Hobson-Webb, Jeff Guptill

P2.081

Incidence of Myasthenia Gravis in an HMO of Buenos Aires, Argentina  Marcelo Rugiero, Mariela Bettini, Marcelo Chaves, Diego Giunta, Jimena Vicens, Edgardo Cristiano

P2.082

A Role for BAFF Receptor (BAFF-R; Cd268) and its Ligand Variant(S) in Early-onset Myasthenia Gravis Thymus  Michael Pütz, Hendrik Döbold, Patrick Stelmach, Kerstin Schlegel, Michael Happel, Wolfgang Oertel, Maria Seipelt, Christian Eienbröker, Bjorn Tackenberg

P2.083 Demographics of Ocular

Myasthenia Gravis  Beau Bruce, Elena Bitrian, Mark Kupersmith, Fritz Zimprich, Jason Peragallo, Thomas Whittaker, Michael Lee

P2.084 Prognostic Factors and

P2.088 Increased Number of Hassall’s Corpuscles in Myasthenia Gravis Patients with Thymic Hyperplasia  Naoko Matsui, Ryuji Kaji

P2.089

A Biosensor Assay for the Detection of Muscle Specific Tyrosine Kinase (MuSK) Antibodies in Myasthenia Gravis Patients  Zahra Pakzad, Ebrima Gibbs, Tariq Aziz, Joel Oger

P2.090

Video-assisted Thoracoscopic Surgery for Myasthenia Gravis Associated with Thymoma: A 13-year Experience  Minas Tzagournissakis, Konstantinos Lasithiotakis, Alexandros Andreou, Michalis Mavridis, Vasileios Mastorodemos, Georgios Amoiridis, Andreas Plaitakis, Georgios Chalkiadakis

P2.091

Association of Neuromyelitis Optica Following Thymectomy in Myasthenia Gravis: Case Report and Retrospective Literature Review of 16 Patients  Sajjad Nasir, V Vedanarayanan, Robert Herndon

P2.092

De Novo Mutation in Sodium Channel Gene SCNBA Causes Neuromuscular Junction Disorder in Early Onset Epileptic Encephalopathy Nina Barisic, Sarah Weckhuysen, Peter De Jonghe, Ingo Helbig, Arvid Suls, Vanja Ivanovic, Ivan Lehman, Branka Bunoza, Petra Grdan

Predictive Value of Electrophysiology for Detecting Thymic Pathology in Patients with Myasthenia Gravis  Tushar Gosavi, G Huang, Stephanie Fook-Chong, Yew Long Lo

58

Succesful Treatment of Carotid-Cavernous Fistula Through a Percutaneous Orbital Approach Ricardo Rangel Guerra

Cerebrovascular Disease and Interventional Neurology: Behavioral, Cognitive, and Miscellaneous

P2.101

P2.115

Postoperative Seizure Outcomes in Patients with Intracerebral Cavernous Malformations  Neha Morparia, Cheolsu Shin, Robert Brown, Teresa Christianson, Kelly Flemming

P2.102

Risk of Bleeding from Antithrombotic Agents (AT) in Patients with Cerebral Cavernous Malformations (CCMs).  Robert Wityk

P2.103

Rare Presentation of Churg-Strauss Syndrome: Intracerebral Hemorrhage, Subdural Hemorrhage and an Intracranial Aneurysm  Mandeep Chahil, Justin Morgan, Nicole Gonzales, Tzu-Ching Wu

P2.104

Inflammatory Cerebral Amyloid Angiopathy Mimicking an Aggressive Glioma  Adam Reynolds, Erica Byrd, Arielle Davis, Mahmud Mossa-Basha, Sandeep Khot

P2.105

Cerebrovascular Disease and Interventional Neurology: Childhood and Young Adult

A Case of Lambert-Eaton Myasthenic Syndrome Presenting with Severe Autonomic Failure Ugonma Chukwueke, Digvijaya Navalkele, Marisara Dieppa, Jaya Trivedi, Jeffrey Elliott, Steven Vernino

P2.095

Influence of Immunosuppressive Medication on TCR Vβ Usage and Thymocyte Maturation Stages in Patients with Early-onset Myasthenia Gravis Christian Eienbröker, Michael Pütz, Kerstin Schlegel, Klaus Gellert, Norbert Sommer, Florian Seitz, Wolfgang Oertel, Bjorn Tackenberg

P2.096

P2.087

P2.100

P2.094

Paraneoplastic Myasthenia Gravis associated with Appendiceal Mucinous Neoplasm  Nicholas Lanciano, Victoria Lawson, William Arnold

P2.085 Low Dose Medication

Myasthenia Gravis in the Elderly: Clinical Characteristics, Treatment Considerations, Complications and Prognosis.  Marcelo Rugiero, Mariela Bettini, Marcelo Chaves, Hernan Gonorazky, Vanesa Pytel, Edgardo Cristiano

P2.114

Predictors of Hemorrhagic Complications from Endovascular Treatment of Cerebral Arteriovenous Malformations  Juan Carlos Llibre, Jose Jordan

P2.093

Cerebrovascular Disease and Interventional Neurology: Acquired and Congenital Vascular Malformations

P2.086

P2.099

Cerebral Amyloid Angiopathy Related Inflammation: Case Reports and Imaging Pitfalls  Mark Mcallister, Melissa Armstrong

Health-related Quality of Life (HRQol ) in Ocular Myasthenia Gravis (OMG) Giuliana Galassi, Alessandra Ariatti, Marina Stefani, Pietro Miceli, Manuela Tondelli, Francesca Benuzzi, Paolo Nichelli and Long-term Outcome in Myasthenia Gravis  Salomi Salins, Barbara Teter, Katelyn Kavak, Nicholas Silvestri, Gil Wolfe

7:30 a.m.–11:00 a.m.

Pial Arteriovenous Fistula and Capillary Malformation-Arterial Venous Malformation (CM-AVM) Associated with RASA1 Mutation: 2 Illustrative Cases  Deepak Gulati, Sunil Manjila, Nicholas Bambakidis, Asim Shahid

P2.097

Intracranial Dural Arteriovenous Fistula Presenting with Recurrent Transient Fluent Aphasia Bardia Nourbakhsh, Julio Rojas -Martinez, Chirantan Banerjee, Roberta Novakovic, Worthy Warnack

P2.098

Cerebral Venous Congestion Caused By Cervical Arteriovenous Fistula: A Rare Delayed Complication Following Heart Transplantation  Hlynur Georgsson, Annapoorna Bhat, Machteld Hillen

P2.106

Etiology and the Cost of Pediatric Stroke  William Hamilton, Haijuan Huang, Eric Seiber, Warren Lo

P2.107

Intra-arterial Treatment in a Child with Embolic Stroke due to Atrial Myxoma  Ido Van Der Wyngaard, Marieke Wermer, Marianne van Walderveen, Geert Lycklama a Nijeholt

Hypertensive Disorders in Pregnancy and Future Risk of Stroke: A Systematic Review  Aravind Ganesh, Neha Sarna, Rahul Mehta, Eric Smith

Undiagnosed Cognitive Impairment Among Patients Referred for Carotid Doppler Evaluation Is Associated with Increased Non-adherence with Medical Treatment of Vascular Risk Factors  Angelia Kirkpatrick, Leslie Guthery, Calin Prodan

P2.116

Neuro-QOL for Assessment of Cognitive Impairment After Stroke: Comparison with Modified Rankin Scale  Rajbeer Sangha, Carlos Corado, Deborah Bergman, Andrew Naidech, David Cella, Richard Bernstein, Yvonne Curran, Shyam Prabhakaran

P2.117

The Role of DiffusionPerfusion Mismatch in the Cognitive Changes of Acute Stroke Patients Amanda Ramadan, Melissa Motta, Rebecca Gottesman, Argye Hillis, Richard Leigh

P2.118

The Feeling that ‘I Can Say it in My Head’ Predicts Word-byWord Success in Subsequent Aphasia Treatment.  William Hayward, Kelli Sullivan, Sarah Snider, Elizabeth Lacey, Rhonda Friedman, Peter Turkeltaub

P2.119

An Unusual Cause of Altered Mental Status: Recurrent Cerebral Air Embolism from Atrial-Esophageal Fistula  Iftekhar Ahmed, Trenton Myers, James Kim

P2.120

Stroke Mortality and its Predictors in Nigeria: Results of a HospitalBased Study  Kolawole Wahab, Emmanuel Sanya, Babatunde Ademiluyi, Bello Abiodun, Wemimo Alaofin

P2.121

Heart Rate Variability and Vibration Perception Threshold in Healthy Young Adults with Parental History of Type 2 Diabetes  Rajesh Goit

Measurement of Hemispheric Volume to Detect and Quantify Early Ischemic Changes in Patients with Ischemic Stroke  Asif Khan, Mushtaq Qureshi, Bernard Galea, Malik Adil, Muhammad Suri, Adnan Qureshi

P2.109

P2.122

P2.108

Stroke in a Young Patient: A Sentinel Presentation of Neurosyphilis and HIV  Elizabeth Flaherty, Shawna Cutting

P2.110

Cardiovascular Risk Factors in Young Adults with Stroke from the AISYF Study  Julieta Mazziotti, Ricardo Reisin

P2.111

Left Ventricular Hypertrophy as a predictor of White Matter Hyperintensities in Young Stroke Patients  Luciana Catanese, Ashkan Shoamanesh, Helena Lau, Jose Romero, Viken Babikian, Carlos Kase, Aleksandra Pikula

P2.112

Ethnic Differences in Ischemic Stroke Subtypes: The Stroke Prevention in Young Adults Study  Megh Trivedi, John Cole

P2.113

Pregnancy Associated Cerebral Ischemia in Women with Sickle Cell Disease  Taqi Zafar, Malik Adil, Muhammad Suri, Adnan Qureshi

2O14 Scientific Abstract Listing and Annual Meeting Information

Safety and Tolerability of Gabapentin for Headache After Aneurysmal Subarachnoid Hemorrhage  Laxmi Dhakal, Michael Mayes, Alexa Richie, William Freeman

P2.123

Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopthy (CADASIL) in Argentina  Maximiliano Hawkes, Miguel Wilken, Veronica Bruno, Virginia Pujol Lereis, Guillermo Povedano, Maria Saccoliti, Ana Lia Taratuto, Sebastian Ameriso

P2.124

Episodic Aphasia After Subdural Hemorrhage Due to Cortical Spreading Depression: A Case Report  Jillianne Grayson, Nirav Shah, Shnehal Patel, Alejandro Forteza

Poster Session II

Cerebrovascular Disease and Interventional Neurology: Evaluation, Cost, and Quality

P2.137

Stroke Patients and Diagnostic Testing—the Weekend Waiting Game!  Sally Mathias, Jessica Lee

Sex Disparities in Access to Stand Alone Primary Stroke Centers: Can Telemedicine Mitigate This Effect?  Catherine Wolff, Amelia Boehme, Tzu-Ching Wu, Michael Mullen, Charles Branas, James Grotta, Sean Savitz, Brendan Carr

P2.126

P2.138

P2.125

Which Diagnostic Tests for Stroke Are the Most Costly and May Not be Necessary?  Seemant Chaturvedi, Kumar Rajamani, Pratik Bhattacharya

P2.127

Implementing a Checklist into Cerebrovascular Service Discharges: A Resident-Driven Quality Improvement Project  Kate Daniello, Melissa Rayhill, Ania Busza, Judith Clark, James Otis

P2.128

Transient Ischemic Attack: Symptom Patterns and Imaging Associations  Elissaios Karageorgiou, David Anderson

P2.129

Stroke Patient Length of Stay Benchmarking and Analysis Elizabeth Diebolt, Shannon Sims, James Conners, Vivien Lee

P2.130

Comparability of Charges and Payments for Hospitalized Stroke Sebina Bulic, May Kim, Shuhan He, Suzie Kazaryan, Steven Cen, Shannon He, William Mack, Nerses Sanossian

Medicare Coverage Increases Odds of In-hospital Mortality But Lack of Insurance Increases Odds of Poor Functional Outcome by Modified Rankin Score (mRS)  Adam Friedant, Dominique Monlezun, Jr, Prerana Baranwal, Melisa Valmoria, Amir Shaban, Alexander George, Ramy El Khoury, Sheryl Martin-Schild

P2.139

Medicare and VA Patients Have More Inpatient Complications and Less Neuroimaging than Uninsured Patients  Prerana Baranwal, Dominique Monlezun, Jr, Mathew Ryan, Denise Pineda, Amir Shaban, Alexander George, Ramy El Khoury, Sheryl Martin-Schild

P2.140

Uninsured Patients May Lack Diagnoses for Chronic Diseases That Are Known Stroke Risk Predictors Prerana Baranwal, Dominique Monlezun, Jr, Joel Lanceta, Amir Shaban, Alexander George, Sheryl Martin-Schild, Ramy El Khoury

P2.148

Age-specific Incidence Rate for Dementia and Alzheimer’s Disease in NIA-LOAD/NCRAD and EFIGA Families  Badri Vardarajan, Kelley Faber, Thomas Bird, David Bennett, Roger Rosenberg, Bradley Boeve, Neill GraffRadford, Alison Goate, Martin Farlow, Robert Sweet, Rafeal Lantigua, Martin Medrano, Ruth Ottman, Daniel Schaid, Tatiana Foroud, Richard Mayeux

P2.149

Distinct Genetic Variants in Alzheimer’s Disease and Type 2 Diabetes  Sun Ju Chung, Seong Yoon Kim, Juyeon Kim, Mi-Jung Kim, Young Jin Kim, Jae-Hong Lee

P2.150

TMEM106B Is a Genetic Modifier of Frontotemporal Lobar Degeneration with C9orf72 Hexanucleotide Repeat Expansions  Alice Chen-Plotkin, Michael Gallagher, Eunran Suh, Murray Grossman, Lauren Elman, Leo McCluskey, John Trojanowski, Virginia Lee, Vivianna Van Deerlin

P2.151

HDLS Family Case Showing X-Linked Recessive Heredity Hisatomo Kowa, Takeshi Uenaka, Takehiro Ueda, Takashi Matsukawa, Shoji Tsuji, Fumio Kanda, Tatsushi Toda

P2.158

Functional Neuroimaging of Sensory Conversion Disorder: The Role of Ancillary Activation  Matthew Burke, Omar Ghaffar, W Staines, Jonathan Downar, Anthony Feinstein

P2.159

Impaired Processing of Positive and Negative Facial Expressions in Right Hemisphere Stroke  Donna Tippett, Cameron Davis, Yessina Gomez, Lydia Trupe, Argye Hillis

P2.160

Models for PTSD Subtypes Classification According to Anxiety and Depressive Dominant Symptomatology  Chen Ryder, Gal RichterLevin, Radi Shahien

P2.161

Longitudinal Volume Loss in Neuroanatomical Regions of Emotion Versus Cognition  Peter Pressman, Yuliana Noniyeva, Nicholas Bott, Shubir Dutt, Bruce Miller, Virginia Sturm, Joel Kramer

P2.162

Asymmetry of Perceived Emotional Expression in Facial Chimeras  Jerry Wei, Steven Sparr

Aging, Dementia, and Cognitive and Behavioral Neurology: General Cognition

P2.141

P2.152

Show or No-show—That Is the Question: Lack of Outpatient Follow-up a After Acute Stroke.  Gauhar Chaudhary, Jessica Lee

Adherence with Post-stroke Follow-up Clinic Visits and Factors Influencing Compliance in a Large Urban Hospital.  Mohammad El-Ghanem, Peter Jin, Vineet Punia, Wenzhuan He, Machteld Hillen

P2.132

P2.142

Aging, Dementia, and Cognitive and Behavioral Neurology: Emotion

Primary CNS Lymphoma Versus Intravascular Lymphoma: Differences in Cognitive Presentation  Mariel Deutsch, Mario Mendez

P2.153

P2.165

P2.131

Use of a Patient Navigation System to Increase Attendance at Stroke Follow-up Appointments  Christina Sarris, Aaron Hajart, Ennis Duffis

P2.133

Gender Differences in Primary Stroke Center Evaluation and Utilization of rt-PA  Michael Mullen, Karen Albright, Amelia Boehme, Scott Kasner, Michael Kallan, Charles Branas, Brendan Carr

Risk Factors More Associated with Ischemic Rather Than Hemorrhagic Stroke in Black Africans: Implications for Epidemiologic Transition  Mayowa Owolabi, Atinuke Agunloye

P2.143

Poor Outcome Among Women Following Intracerebral Hemorrhage Preet Varade, Seemant Chaturvedi, Pratik Bhattacharya

Cerebrovascular Disease and Interventional Neurology: Disparity

Aging, Dementia, and Cognitive and Behavioral Neurology: Genetics

P2.134

P2.144

Are Hispanic Subarachnoid Hemorrhage Patients in Border States Treated Differently Than Those Admitted in Non-Border States?  Ameer Hassan, Taqi Zafar, Malik Adil, Muhammad Umair, Ahmed Malik, Wondwossen Tekle, Olive Sanchez, Adnan Qureshi

P2.135

Disparities in Access to Primary Stroke Centers: Geography, Not Gender, Race, or Ethnicity  Michael Mullen, Ariel Bowman, Douglas Wiebe, Catherine Wolff, Karen Albright, Jason Roy, Laura Balcer, Charles Branas, Brendan Carr

P2.136

Are There Disparities in Thrombolytic Treatment and Mortality in Acute Ischemic Stroke in the Hispanic Population Living in Border States Versus Non-Border States?  Ameer Hassan, Malik Adil, Taqi Zafar, Muhammad Umair, Wondwossen Tekle, Olive Sanchez, Adnan Qureshi

Sanger Sequencing Exons of BDNF Gene Derived from a Latino Sample  Sara Dawit, Jazmin Acosta, Mia Champion, Stefanie Velgos, Gabriel Shaibi, Lawrence Mandarino, Nicole Cevette, Richard Caselli, Yonas Geda

P2.145

Lack of AGG Interruptions in FMR1 Is Associated with Cognitive Impairment  Deborah Hall, Victor Kaytser, Raj Shah, David Bennett, Elizabeth BerryKravis

P2.146

Genome-wide Gene-based Analysis of Exome Array Data for Rare Variants in Alzheimer’s Disease  Sun Ju Chung, Seong Yoon Kim, Juyeon Kim, MiJung Kim, Young Jin Kim, Jae-Hong Lee

P2.147

Expression QTL Studies in LOAD and PSP Brains by Next-generation RNA Sequencing  Nilufer Taner, Chen Wang, Minerva Carrasquillo, Mariet Allen, Curtis Younkin, Daniel Serie, Vernon Pankratz, Thuy Nguyen, Li Ma, Kimberly Malphrus, Sarah Lincoln, Ronald Petersen, Neill Graff-Radford, Steven Younkin, Dennis Dickson, Yan Asmann



Altered CpG Methylation of APP, MAPT and GSK3B in Sporadic Alzheimer’s Disease  Atsushi Iwata, Hiroyuki Hatsuta, Shigeo Murayama, Shoji Tsuji

Influence of the Tau Haplotype on Progression and Treatment Response of Neuropsychiatric Symptoms in People with Alzheimer’s Disease  Clive Ballard, Anne Corbett, Byron Creese

P2.154

Visual Hypoemotionality (Secondary Visual Derealization) in a Patient with a Right Posterior Temporoparietal Lesion  David Perez, Sashank Prasad, Diler Acar, Mary-Ellen Meadows, Alexandra Golby, Barbara Dworetzky

P2.155

Major Depression as Initial Manifestation of Limbic Lewy Body Dementia a Clinico-pathological Report  Bernard Michel, Henri Becker, Jean-Francois Pelissier, Bradley Boeve, Nathalie Sambuchi, Annie Bartolin, Catherine Gallant, Jean-Claude Saint Jean, Hui-Mei Chen, Charles Rouyer, Jean Michel Azorin, Ronald Petersen

P2.156

Evaluation of Emotional Blunting in Behavioral Variant Frontotemporal Dementia Compared to Alzheimer’s Disease  Aditi Joshi, Joseph Barsuglia, Michelle Mather, Elvira Jimenez, Jill Shapira, Mario Mendez

P2.157

Autistic Symptoms in a Geriatric Population with Mild Cognitive Impairment and Early Dementia Danielle Crawford, Erin Abner, Paul Glaser, Gregory Jicha

Tuesday April 29



First Authors stand by Posters from 7:30 a.m.–9:00 a.m.

P2.163

Diffuse Lewy Body Disease and Associated Balint’s Syndrome: A Case Series  Ramsey Falconer, Sean Rogers, Fahd Amjad, Benjamin Osborne

P2.164

Using Eye-Movement Trackings to Investigate Mechanisms of Word-object Associations in Primary Progressive Aphasia  Mustafa Seckin, Joel Voss, M. Mesulam, Emily Rogalski, Robert Hurley

P2.166

Nonverbal Oral Apraxia in Primary Progressive Aphasia and Apraxia of Speech  Hugo Botha, Joseph Duffy, Edythe Strand, Jennifer Whitwell, Keith Josephs

P2.167

Routine Cognitive Screening in a General Neurology Clinic: Impact on Physician Behavior  Michael Rosenbloom, Terry Barclay, Maria Pyle, Amanda Cagan, Ann Hanson, Leah Hanson

P2.168

Impaired Grammar in the Speech of Amyotrophic Lateral Sclerosis  Collin York, Lauren Elman, Leo McCluskey, Sharon Ash, Murray Grossman

P2.169

Unawareness of Partners’ Abilities in Aged Subjects  Vahid Behravan, Paul Eslinger, A. Barrett

P2.170

Neurobehavioral Disorders in Parkinsonian Patients Without Dopamine Deficits (SWEDD)  Amin Demerdash, Kenneth Heilman, Joanna Myers, Chase Mitchell, David Standaert, Frank Skidmore

P2.171

A Japanese Family with Idiopathic Basal Ganglia Calcification with Novel SLC20A2 Mutation Presenting with Late-onset Hallucination and Delusion  Kensaku Kasuga, Takuya Konno, Masatoyo Nishizawa, Takeshi Ikeuchi

Fast, Easy Registration Online  ·  AAN.com/view/AM14

59



Tuesday, April 29 P2.172

Bilingualism Is Associated With Less Severe Cognitive Impairment  Claudia Padilla, Elvira Jimenez, Joseph Barsuglia, Aditi Joshi, Edmond Teng, Mario Mendez

P2.173

Differential Longitudinal Changes in Cognition Among Amyotrophic Lateral Sclerosis (ALS) Patients Sharon Xie, Katya Rascovsky, Ashley Boller, Xiaoyan Han, Leo McCluskey, Lauren Elman, David Libon, Murray Grossman

P2.174

Subjective Cognitive Impairment in a French Sample Bernard Michel, Nathalie Sambuchi, Yonas Geda, Isabelle Muraccioli, Veronique Paban, Elisabeth Jouve, Rolland Sambuc, Hui-Mei Chen, Annie Bartolin, Catherine Gallant, Jean-Claude Saint Jean, Charles Rouyer, Christian Brosset, Jean-Michel Azorin, Beatrice Alescio-Lautier, Ronald Petersen

P2.175

Cognitive Decline Is Associated with Progressive Grey Matter Disease in Amyotrophic Lateral Sclerosis (ALS)  Christopher Olm, Lauren Elman, Leo McCluskey, Corey McMillan, Murray Grossman

P2.176

Neurological Examination Findings in Autistic Adults  Bryan Woodruff, Joseph Hentz, Amy Duffy, Elena Pollard, Christopher Smith, Yonas Geda

P2.177

Mild Cognitive Impairment: Neuropsychiatric Symptom Prevalence within Cognitive Subtypes and Obesity  Ashley Hannah, Andrea Bozoki

P2.178

Social and Executive Contributions to Discourse Limitations in Amyotrophic Lateral Sclerosis Anna Menaged, Sharon Ash, Christopher Olm, Corey McMillan, Murray Grossman, Lauren Elman, Leo McCluskey

P2.179

Dissociating the Body Schema: Evidence from Two Case Studies  Jared Medina, Emily Baumert, Megan Ziegler

P2.180

Deficits in Sentence Expression in Amyotrophic Lateral Sclerosis  Sharon Ash, Christopher Olm, Corey McMillan, Ashley Boller, David Irwin, Leo McClusky, Lauren Elman, Murray Grossman

P2.181

Speaking While Gesturing Adversely Affects Limb Praxis in pAD. A. Barrett, Livingston Dore

P2.182

Alabama Brief Cognitive Screener (ABCs): Design and Initial Clinical Experience  Marissa Natelson Love, David Geldmacher

Epilepsy and Clinical Neurophysiology: Genetics P2.183

CLN6 Mutations Cause Teenage-onset Progressive Myoclonus Epilepsy  Danielle Andrade, Tara Paton, Julie Turnbull, Christine Klein, Christian Marshall, Stephen Scherer, Berge Minassian

60

P2.184

Mild Case of UnverrichtLundborg Disease (ULD) Mimicking Juvenile Myoclonic Epilepsy (JME) in Adulthood  Eva Andermann, Dina Amrom, Mahmoud Heshmati Moghaddam, Frederick Andermann, Tarja Joensuu, Anna-Elina Lehesjoki

P2.185

LGI1 Mutation Presenting as Idiopathic Generalized Epilepsy: Importance of Family History for Genetic Testing Dina Amrom, Frederick Andermann, Hans Atli Dahl, Eva Andermann

P2.186 Lacosamide-responsive

Status Epilepticus and Epileptic Spasm in Fumarase Deficiency  France Fung, Patricia Musolino, Ronald Thibert

P2.187

Aicardi Syndrome: Long-term Evolution  Anfal Ali, Nicky Wu, Felippe Borlot, Timo Krings, Danielle Andrade

P2.188

Dravet Syndrome: Seizure Control and Gait in Adults with Different SCN1A Mutations  Jennifer Rilestone, Fernando Coelho, Berge Minassian, Danielle Andrade

P2.189

The Prognosis of Primary Generalized Epilepsy in Patients with Parental Consanguinity: A One-year Retrospective Study  Hussam Assiri, Abdulmajeed Bajunaid, Fawzi Babtain, Muthusamy Velmurugan

P2.190

First Time Seizure in Adult Female as Presentation of Ornithine Transcarbamoylase Deficiency: A Case Report and Literature Review Michael Pizzi, Suparna Krishnaiengar

P2.191

Unusual Presentation of Left Temporal Lobe Epilepsy Due to Large Sphenoidal Encephalocele and Good Epilepsy Surgery Outcome  Tiffany Fisher, Sasaki-Adams Deanna, Hae Won Shin

P2.192

Next Step for Personalized Medicine in Epilepsy: Pharmacogenomic Testing-based Antiepileptic Drugs in Refractory Epilepsy  Andres Cruz, Pedro Bermejo

P2.193

A Novel Gene (Myclonin 3) for Classic Juvenile Myoclonic Epilepsy  Dongsheng Bai, Marco Medina, Reyna Duron, Julia Bailey, Maria Alonso, Toshimitsu Suzuki, Miyabi Tanaka, Iris Martinez-Juarez, Adriana Ochoa, Aurelio Jara-Prado, Jose Serratosa, Kazuhiro Yamakawa, Antonio Delgado-Escueta

MS and CNS Inflammatory Disease: Treatment Safety P2.194

Teriflunomide Treatment Is Not Associated with Increased Risk of Infections: Pooled Data from the Teriflunomide Development Program Barry Singer, Giancarlo Comi, Aaron Miller, Mark Freedman, Myriam Benamor, Philippe Truffinet

P2.195

Cardiovascular Effects of Combined Administration of Siponimod and Popranolol—Importance of Sequencing During Coadministration  Shibadas Biswal, Florine Polus, Atul Pawar, Uday Kiran Veldandi, Eric Legangneux

7:30 a.m.–11:00 a.m. P2.196

Short-term and Long-term Effects of Fingolimod on the Cardiovascular Autonomic Nervous System  Judith Eisele, Jowita Zwierzanska, Manja Reimann, Silke Prieur, Kristin Haink, Thorsten Schultheiss, Tjalf Ziemssen

P2.206 A Case of Hemophagocytic

P2.197

P2.207

Good Cardiac Safety in Patients with Relapsing Remitting Multiple Sclerosis Upon First Fingolimod Dose  Volker Limmroth, Susanne Hoyer, Stephan Schmidt, Michael Lang, Tjalf Ziemssen

P2.198

Successful Detection and Management of Immune Thrombocytopenia in AlemtuzumabTreated Patients with Active RelapsingRemitting Multiple Sclerosis  Adam Cuker, Roberto Stasi, Jeffrey Palmer, Pedro Oyuela, David Margolin, Ann Bass

P2.199

Thyroid Autoimmune Adverse Events in Patients Treated with Alemtuzumab for Relapsing-Remitting Multiple Sclerosis: Four-year Follow-up of the CARE-MS Studies  Cary Twyman, Pedro Oyuela, Jeffrey Palmer, David Margolin, Colin Dayan

P2.200 Safety Profile of Delayed-

Release Dimethyl Fumarate in RelapsingRemitting Multiple Sclerosis (RRMS): Longterm Interim Results From the ENDORSE Extension Study  Ted Phillips, Robert Fox, Krzysztof Selmaj, Ray Zhang, Mark Novas, Marianne Sweetser, Vissia Viglietta, Ralf Gold

P2.201

Safety of Using Diseasemodifying Therapy Post-alemtuzumab Treatment in Patients with RelapsingRemitting Multiple Sclerosis in the Core and Extension Phases of CAMMS223, CARE-MS I, and CARE-MS II Studies Keith Edwards, Christopher LaGanke, Pedro Oyuela, Jeffrey Palmer, David Margolin

P2.202 Baseline Characteristics

and Interim Analysis Results of the Fingolimod Cohort in the Worldwide Post-approval Safety Program (PASSAGE)  Paul Giacomini, Helmut Butzkueven, Stanley Cohan, Tomas Olsson, Dietrich Rothenbacher, Belinda Weller, Tjalf Ziemssen, Anu Gupta, Malika Cremer, Tricia Blankenbiller, Erika Rochotte, Davorka Tomic, Philipp Von Rosenstiel, Maria Trojano

P2.203 Pooled Safety Data from

Four Placebo-Controlled Teriflunomide Studies  Thomas Leist, Mark Freedman, Myriam Benamor, Philippe Truffinet, Deborah Dukovic, Giancarlo Comi

P2.204 Prospective Evaluation

of Development of Skin Rashes in MS Patients Treated with Daclizumab High Yield Process  Irene Cortese, Kaylan Fenton, Joan Ohayon, Edward Cowen, John DiGiovanna, Bibiana Bielekova

P2.205 Safety and Tolerability of

Escalating Doses of Laquinimod, an Oral Immunomodulatory Agent in Development for Treatment of Relapsing-Remitting Multiple Sclerosis  Hayrettin Tumani, Tjalf Ziemssen, Friedemann Paul, Martin Marziniak, Nils Richter, Christoph Heesen, Maya Marglit, Yulia Sidi, Tali Gorfine, Yossi Gilgun-Sherki

2O14 Scientific Abstract Listing and Annual Meeting Information

Lymphohistiocytosis Syndrome in a Patient with Multiple Sclerosis on Fingolimod Therapy.  Pedro Abreu, Carla Peixoto, Claúdia Carvalho, Lurdes Santos, António Sarmento, Maria José Sá A Comparison of the Safety/ Tolerability and Pharmacodynamics of Acthar Gel and Methylprednisolone with Regimens Utilized for the Treatment of MS Exacerbations  Stacie Bell, Jennifer Vincent, Vakessa Hammock, Karen Welch, Julia Chung, Mary Nyberg, Patrice Becker, David Young

P2.208 Efficacy and Safety of

Fingolimod in Hispanic Patients: Pooled Data from Three Phase 3 Clinical Trials  Angel Chinea, Regina Alvarenga, Davorka Tomic, Allitia DiBernardo, Xiangyi Meng, Kathleen Hawker

P2.209 Alemtuzumab Has Similar

Efficacy and Safety in Active RelapsingRemitting Multiple Sclerosis (RRMS) Patients Who Were Treatment-Naive or Who Relapsed on Prior Therapy David Margolin, Bernd Kieseier, Jeffrey Palmer, Tjalf Ziemssen

P2.210

Long-term Safety of Fingolimod: Interim Evaluation of Data from the LONGTERMS Trial  Jeffrey Cohen, Philipp Von Rosenstiel, Rebecca Gottschalk, Linda Cappiello, Ying Zhang, Ludwig Kappos

P2.211

Delayed Third Degree Atrioventricular Block with Pacemaker Placement in a Multiple Sclerosis Patient on Fingolimod Treatment  Johann Sellner, Barbara Holl, Peter Wipfler, Vaclav Chroust, Georg Pilz, Maximilian Winhard, Andrea Harrer, Katrin Oppermann, Eugen Trinka, Jorg Kraus

P2.212

No Clinically Significant Effect on Pulmonary Function Observed with Siponimod (BAF312) Alone or in Combination with Propranolol in Healthy Adult Subjects  Shibadas Biswal, Florine Polus, Atul Pawar, Uday Kiran Veldandi, Eric Legangneux

P2.213

Bullous Drug Eruption with Dimethyl Fumarate  Amir Khoiny, Noushin Khoiny

P2.214

Early Tolerability of Dimethyl Fumarate for Treatment of Multiple Sclerosis  Samuel Cohn, Robert Bermel, Robert Fox, Jeffrey Cohen, Daniel Ontaneda

P2.215

Report an Unusual Thrombotic Complication Two Months After Starting Fingolimod  Nancy Nealon, Nataliya Ternopolska, Halina White

P2.216

Tolerability, Safety and Efficacy of Fingolimod in Clinical Pratice  Jean-Claude Ongagna, Carole Berthe, Nicolas Collongues, Fréderic Blanc, Jerome De Seze

P2.217

GNbAC1, a Humanized Monoclonal Antibody Against the Multiple Sclerosis Associated Retrovirus Envelope Protein, Is Well Tolerated in Patients with Multiple Sclerosis.  Tobias Derfuss, Francois Curtin, Alois Lang, Herve Perron, Ludwig Kappos, Patrice LaLive

Poster Session II

P2.218

The Autonomic Balance Predicts Cardiac Effects After First Dose of Fingolimod  Silvia Rossi, Camilla Rocchi, Valeria Studer, Caterina Motta, Benedetta Lauretti, Giorgio Germani, Giulia Macchiarulo, Gerolama Marfia, Diego Centonze

P2.219

Electrocardiogram Monitoring After the First Fingolimod Doses Begoña Palazon, Ester Carreon, Rocio Hernandez Clares, Judith Jimenez, Gema Salgado, Encarnación Andreu, Jose Javier Martín, Jose Meca

P2.220 Excessive Blood Pressure

Increase during Sustained Handgrip Testing Predicts Bradycardia upon Fingolimod Treatment  Max Hilz, Ralf Linker, Tassanai Intravooth, Sebastian Moeller, De-Hyung Lee, Stefan Schwab, Julia Koehn

P2.221

Safety and Dosing of Autologous Neural Progenitors Injected Intrathecally in Multiple Sclerosis Patients: Results of a Pilot Study  Saud Sadiq, Sydney Chirls, Daniel Koffler, Violaine Harris

P2.222 The Use of MRI to Monitor

the Safety of Anti-LINGO-1: Findings from Phase I Studies in Healthy Volunteers and Subjects with MS  Nancy Richert, Isaac Melamed, Hakop Gevorkyan, Lei Xu, Diego Cadavid

P2.223 Long-term Safety of Rituximab and Peripheral B-Cell Depletion in Multiple Sclerosis and Other CNS Autoimmune Disorders  Anza Memon, Shitiz Sriwastava, Fen Bao, Evanthia Bernitsas, Adil Javed, Christina Caon, Omar Khan

P2.224 Reversible Cerebral

Vasoconstriction Syndrome and Fingolimod: Culprit or Innocent Bystander Jason Fleming, Matthew West

P2.225 Life Threatening Asthmatic

Crisis After 6 Months of Fingolimod Treatment  Matteo Caporro, Claudio Gobbi, Chiara Zecca

P2.226

Tumefactive Multiple Sclerosis in a Patient on Fingolimod  YuanKai Lee, Vijay Sawlani, Gordon Mazibrada

P2.227

Gastrointestinal Tolerability of Delayed-Release Dimethyl Fumarate in a Multicenter, Open-Label Study of Patients with Relapsing Forms of Multiple Sclerosis  Edward Fox, Alberto Vasquez, William Grainger, Tina Ma, Jie Li, Javier Zambrano

P2.228 Transient Neurologic

Worsening After Initiation of Dimethyl Fumarate Therapy in Progressive Multiple Sclerosis Patients  James Stark, Sydney Chirls, Saud Sadiq

P2.229

Absence of a Relevant Effect on Cardiac Repolarization in a QT/QTc (TQT) Study of RPC1063, a Novel, Selective S1P1 Receptor Agonist, in Healthy Adult Volunteers  Hartung Jeffrey, Allan Olson, Robert Peach, Marcus Boehm, Boaz Mendzelevski, Heather Smith, Christine Pan, Gregg Timony, Sheila Gujrathi

P2.230 Dimethyl Fumarate Tolerability and Treatment Adherence Amongst Patients with Multiple Sclerosis Enrolled in Specialty Pharmacy Services. Stephanie Holliday, Alysha Robinson

P2.231

Severe Relapse in a Multiple Sclerosis Patient Associated with Ipilimumab Treatment for Metastatic Melanoma  Edward Gettings, Chris Hackett, Thomas Scott

P2.232

Effects of Therapeutic and Supratherapeutic Doses of Siponimod (BAF312), a Selective S1P1,5 Receptor Modulator, on Cardiac Repolarization: Results of a Thorough QTc (TQT) Study  Kasra Shakeri-Nejad, Louise Mooney, Vassilios Aslanis, Uday Kiran Veldandi, Nicole Pezous, Eric Legangneux

P2.233

Teriflunomide: Non-Clinical Evaluation Demonstrates no Effect on Sperm DNA or Male Fertility Lynn Davenport, Andreas Czich, Sandrine Turpault

Pediatric MS and Other Demyelinating Diseases P2.234

The Symbol Digit Modalities Test Is an Effective Cognitive Screen in Pediatric Onset Multiple Sclerosis (MS)  Lauren Krupp, Leigh Charvet, Rebecca Cleary, Kate Bartolotta, Livana Koznesoff, Rachel Beekman, Anita Belman

P2.235

Downward Educational Trajectory Is Seen in Children and Young Adults After Diagnosis of Pediatric MS  Stephanie Grover, Austin Sye, Berengere Aubert-Broche, Brenda Banwell, Louis Collins, E. Ann Yeh

P2.236

Phenotypic and Functional Analysis of Immune Cell Subsets in Pediatric-onset Multiple Sclerosis (MS): Towards Definition of Earliest Disease Mechanisms  Mukanthu Nyirenda, Rui Li, Craig Moore, Ayal Rozenberg, Ayman Rezk, Trina Johnson, Dessa Sadovnick, Douglas Arnold, Ruth-Ann Marrie, Brenda Banwell, Amit Bar-Or

P2.237

Results of a Population of YOUTH MS; With More Than Ten Years of Follow Up: Some Entity to Think About. C. Curbelo, Maria Curbelo, A. Martínez, G. Rojas, J. Steinberg, A. Carrá

P2.238 Fingolimod in Pediatric MS:

Design of a Double-blind Study Versus Interferon β-1a IM  Tanuja Chitnis, Brenda Banwell, Jutta Gaertner, Goeril Karlsson, Bingbing Li, Martin Bernhard Merschhemke, Norman Putzki

P2.239

Evaluation of Thalamic Fraction in Adults with Pediatric-Onset MS  Samira Farough, Antonia Ceccarelli, Svetlana Egorova, Tanuja Chitnis

P2.240 Clinical and MRI Phenotype

of Children with MOG antibodies Cristina Fernandez Carbonell, David Vargas Lowy, Mussalam Alexander, Brian Healy, Katherine McLaughlin, Kai Wucherpfenning, Tanuja Chitnis



P2.241

Myelin Oligodendrocyte Glycoprotein (MOG) Auto-antibodies in Children Predicts a Non-MS Course of Acquired Demyelination Syndrome (ADS).  Yael Hacohen, Michael Absoud, Kumaran Deiva, Marc Tardieu, Evangeline Wassmer, Ming Lim, Angela Vincent, Patrick Waters

P2.249

P2.242

P2.250 Fingolimod to Treat Severe

Rate of Agreement for Manual and Automated Techniques for Determination of New T2 Lesions in Children with Multiple Sclerosis and Acute Demyelination  Leonard Verhey, Colm Elliott, Helen Branson, Cristina Philpott, Manohar Shroff, Tal Arbel, Brenda Banwell, Douglas Arnold

P2.243 Radiologically Isolated

Syndrome in Children: Report of 5 Children with Long-Term Follow-Up Mefkure Eraksoy, Zuhal Yapici, Pinar Tekturk, Murat Kurtuncu, Hifzi Ozcan

MS and CNS Inflammatory Disease: Progressive Multifocal Leukoencephalopathy Risk P2.244 Low Body Weight

as a Potential Surrogate Risk Factor for Progressive Multifocal Leukoencephalopathy  John Foley, Mark Gudesblatt, Myassar Zarif, Ellen Lathi

P2.245 Lipid-Specific IgM Bands

Contribute to Stratify PML Risk in MS Patients Treated with Natalizumab Luisa Villar, Lucienne Costa-Frossard, Thomas Masterman, Oscar Fernandez, Xavier Montalban, Bonaventura Casanova, Guillermo Izquierdo, Francisco Coret Ferrer, Hayrettin Tumani, Albert Saiz, Rafael Arroyo, Katharina Fink, Laura Leyva, Carmen Espejo, Roberto Alvarez-Lafuente, Javier Olascoaga, Javier Olaskoaga Urtaza, Agustin Oterino, Sara Llufriu Duran, Florian Lauda, Clara De Andres, Juan Antonio Garcia-Merino, Ricardo Fernandez-Bolaños, Lamberto Landete Pascual, Eduardo Aguera Morales, Santiago Diaz Nicolas, Manuel Menendez, Laura Navarro, Domingo Perez, Lluis Ramio, Fernando Sanchez Lopez, Pedro Serrano Castro, Alberto Tuñon, Jose Alvarez-Cermeño

P2.246

Transient Punctuate Gadolinium-enhancing Lesions Preceding Natalizumab-associated Progressive Multifocal Leukoencephalopathy (PML)  Giovanni Castelnovo, Eric Thouvenot, Dimitri Renard, Guillaume Taieb

P2.247

Modeling PML Risk in JCV Sero-Negative Natalizumab-Treated MS Patients  Robert Carruthers, Tanuja Chitnis, Brian Healy

P2.248 Association Between

Infratentorial Onset of Progressive Multifocal Leukoencephalopathy (PML) and Long-Term Exposure to Natalizumab (NAT)  Robert Hoepner, Jonas Ahlbrecht, Ruth Schneider, Stefanie Dahlhaus, Ortwin Adams, Andrew Chan, Martin Stangel, Ralf Gold

Excellent Outcome in Natalizumab-Associated PML Due to Early Diagnosis and Optimal Treatment Georg Pilz, Andrea Harrer, Peter Wipfler, Katrin Oppermann, Johann Sellner, Shahrzad Afazel, Elisabeth Haschke-Becher, Theo Rispens, Desiree van der Kleij, Eugen Trinka, Jorg Kraus Multiple Sclerosis After Natalizumabassociated Progressive Multifocal Leukoencephalopathy: A Valid Option?  Elisabeth Maillart, Céline Louapre, Catherine Lubetzki, Caroline Papeix

P2.251

Multicenter Retrospective Study of extended Dosing of Natalizumab in Multiple Sclerosis: A Strategy for Mitigating Risk of Progressive Multifocal Leukoencephalopathy While Maintaining Efficacy?  Joseph Herbert, Lana Zhovtis Ryerson, Carmelo Tornatore, John Foley, Bianca Weinstock-Guttman, Ilya Kister, Krupa Pandey, Gina Remington, Teresa Frohman, Eugene Major, Sara Qureshi, Shin Beh, Darin Okuda, Puspa Utomo, Channa Kolb, David Hojnacki, Elliot Frohman

Tuesday April 29



First Authors stand by Posters from 7:30 a.m.–9:00 a.m.

P2.252

Immune Modulation During Natalizumab Treatment of Multiple Sclerosis.  Jeffrey Greenstein

P2.253

Dynamics of the Anti-JCvirus Antibody Index in an Austrian MS Cohort  Peter Wipfler, Andrea Harrer, Georg Pilz, Johann Sellner, Michael Guger, Gerhard Ransmayr, Eugen Trinka, Jörg Kraus

MS and CNS Inflammatory Disease: Neuro-Ophthalmology and Optical Coherence Tomography P2.254 Optical Coherence Tomography Correlates of Clinical and Imaging Outcomes in Early Multiple Sclerosis  Amir Hadi Maghzi, Nisha Revirajan, Laura Julian, Rebecca Spain, Ellen Mowry, Shuang Liu, Jacqueline Marcus, Chengshi Jin, Ari Green, Charles McCulloch, Daniel Pelletier, Emmanuelle Waubant P2.255 OCT, Visual Function and

MRI Measures in Acute Optic Neuritis: Baseline Data from a Clinical Trial Rhian Raftopoulos, Simon Hickman, Ahmed Toosy, Claudia Wheeler-Kingshott, Daniel Altmann, Shahrukh Mallik, David Paling, Marios Yiannakas, Klaus Schmierer, Basil Sharrack, Rose Sheridan, Gavin Giovannoni, David Miller, Raju Kapoor

P2.256

Cross-platform Comparison of Retinal Neuronal Layers in Multiple Sclerosis Utilizing a Novel Open-Source Optical Coherence Tomography Automated Segmentation Algorithm  Pavan Bhargava, Andrew Lang, Omar Al-Louzi, Aaron Carass, Shiv Saidha, Jerry Prince, Peter Calabresi

P2.257

Diffusion Tensor Imaging Correlates of Retinal Nerve Fiber Layer Thinning in Early Multiple Sclerosis  Nataliya Ternopolska, Michael Dayan, George Parlitsis, Nancy Nealon, Jai Perumal, Timothy Vartanian, Szilard Kiss, Susan Gauthier

Fast, Easy Registration Online  ·  AAN.com/view/AM14

61



Tuesday, April 29 P2.258 Optic Nerve Head Blood

Flow Assessment by Optical Coherence Tomography Angiography May Be More Sensitive Than Retinal Nerve Fiber Layer Thickness in Detecting Multiple SclerosisRelated Optic Nerve Dysfunction Rebecca Spain, Xiaogang Wang, Yali Jia, Ou Tan, Dennis Bourdette, David Huang

P2.259

In Vivo Assessment Of Retinal Neuronal Layers in Multiple Sclerosis Patients  Muhammad Taimur Malik, Brian Healy, Bonnie Glanz, Howard Weiner, Tanuja Chitnis

P2.260

Factor Affecting Recovery from Acute Optic Neuritis in Multiple Sclerosis Patients  Muhammad Taimur Malik, Brian Healy, Leslie Benson, Pia Kivisakk, Alexander Musallam, Howard Weiner, Tanuja Chitnis

P2.261

Retinal Structural Injury Is Worse in African-Americans than Caucasians with Multiple Sclerosis  Jessica Chorostecki-Vigrass, Ginny Bao, Fen Bao, Shah Aashka, Carla Santiago Martinez, Alexandros Tselis, Christina Caon, Evanthia Bernitsas, Navid Seraji-Bozorgzad, Elliot Frohman, Omar Khan

P2.262

Axonal Protective Role of LINGO-1 Blockade in the Visual System: Results from a Study in Rats and Design of a Phase 2 Clinical Trial for BIIB033, an Anti-LINGO-1 Monoclonal Antibody, in Subjects with a First Episode of Acute Optic Neuritis  Diego Cadavid, Laura Balcer, Steven Galetta, Bing Hu, Kwok-Fai So, Blake Pepinsky, Sha Mi

P2.263

Color Vision Impairment Is Associated with Disease Severity in Multiple Sclerosis  Elena MartínezLapiscina, Santiago Ortiz-Pérez, Elena Fraga, Eloy Martínez-Heras, Iñigo Gabilondo, Sara Llufriu, Santiago Bullich, Marc FiguerasRoca, Albert Saiz, Bernardo SanchezDalmau, Pablo Villoslada

P2.264

Quantification of Macular Blood Flow Volume and Microvascular Network in Multiple Sclerosis (MS) Hong Jiang, Delia Cabrera DeBuc, Silvia Delgado, Aizhu Tao, Byron Lam, Jianhua Wang

MS and CNS Inflammatory Disease: Neuromyelitis Optica and Neuromyelitis Optica Spectrum Disorders P2.265

Estimated Incidence and Prevalence of Neuromyelitis Optica in the England from 1998 to 2011 Cris Constantinescu, I-Jun Chou, Chang-Fu Kuo, Radu Tanasescu, William Whitehouse

P2.266

Aquaporin-4 Antibodypositive Cases Beyond Current Diagnostic Criteria for NMO spectrum Disorders  Douglas Sato, Ichiro Nakashima, Toshiyuki Takahashi, Tatsuro Misu, Patrick Waters, Hiroshi Kuroda, Shuhei Nishiyama, Chihiro Suzuki, Yoshiki Takai, Kazuo Fujihara, Yasuto Itoyama, Masashi Aoki

P2.268

Anti-Aquaporin-4 Antibodies Without Optic Neuritis or Transverse Myelitis  Robert Joshua, Bonnie Keung, Meena Gujrati, Michael Zagardo, Jorge Kattah

P2.269

Neuromyelitis Optica with Severe Behavioral Dysregulation: A Case Report  Teri Schreiner, Cassie Karlsson, Harrison Levine, Julia Barnes, John Binder, Robin Gabriels, Carol Beresford

P2.270

Hydrocephalus in Neuromyelitis Optica  Stacey Clardy, Claudia Lucchinetti, Karl Krecke, Vanda Lennon, Orna O’Toole, Brian Weinshenker, Clara Boyd, Stephen Krieger, Corey McGraw, Yong Guo, Sean Pittock

P2.271

Presence of HLA DR10 in Mexican Patients with Neuromyelitis Optica (Devic’s Disease)  Veronica Rivas, Jose de Jesus Flores, Teresa Corona Vazquez, Julio Granados

P2.272

Distinct Acute Spinal Cord Syndrome Between Aquaporin4IGG Seropositive and Seronegative Longitudinally Extensive Transverse Myelitis  Samira Apostolos-Pereira, Douglas Sato, Frederico Jorge, Paula Melo, Paulo Marchiori, Dagoberto Callegaro

7:30 a.m.–11:00 a.m. P2.280 The Course Of Ocular

Myasthenia Gravis: A Retrospective Study Of 162 Patients  Joao Lemos, Lina Nagia, Khawla Abusamra, Brooke Johnson, Wayne Cornblath, Jonathan Trobe, Christopher Glisson, Sunita Yedavally, David Kaufman, Eric Eggenberger

P2.281

Role of Mitochondrial Reactive Oxygen Species in Cell Death Caused by Connexin 26 Mutations Associated with Keratitis-ichthyosisDeafness Syndrome  Xueshui Guo, Sabrina Yum

P2.282 Modified Brainstem Auditory Evoked Responses Are Associated with Elevated Intracranial Pressure in Subjects with Idiopathic Intracranial Hypertension  Heather Moss, John Fino, Heeren Patel, James Stone

P2.283 Transcranial Direct Current

Stimulation for the Treatment of Chronic Tinnitus: A Randomized, Double-Blind, Sham Controlled Study  David Benninger, Natassja Pal, Marianne Stephan, Francois Herrmann, Raphael Maire

P2.284 Evolution of Macular Findings

Is Optic Neuritis Incidence Rising? Evidence from an Epidemiological Study in Barcelona, Spain 20082012  Elena Martínez-Lapiscina, Elena Fraga, Xavier Pastor, Mónica Gómez, Artur Conesa, Raimundo Lozano-Rubí, Bernardo Sanchez-Dalmau, Alvaro Alonso, Pablo Villoslada

P2.293

Optical Coherence Tomography Visualization of Optic Nerve Head Structure Detects Acute Changes in the Intracranial Pressure  Aashish Anand, Anastas Pass, Eusebia Calvillo, Rosa Tang, Christian Cajavilca, Mian Urfy, Jose Suarez, Chethan Rao, Eric Bershad

P2.294

Comparison Rate Between Headshaking Maneuver And Vibration Maneuver in Ageotrophic Horizontal BPPV  Hyoung Suk Han, Dae Soo Shin

P2.295

Endovascular Treatment of Cerebral Venous Sinus Thrombosis with Combination of Rheolytic Thrombectomy, Angioplasty and tPA Thrombolysis Reversed Severely Elevated ICP Syndrome: A Case Study.  Takamasa Higashimori, Joshua Seinfeld, Victoria Pelak

on Optical Coherence Tomography (OCT) in Papilledema  Farah Villanueva, Fawzi Abukhalil, Mark Morrow

P2.296

P2.285 Measuring Transmission Delay

P2.297

P2.274

P2.286 Retinal Ganglion Cell Layer

P2.298

Neuro-ophthalmology/ Neuro-otology I

P2.287

P2.299

P2.273

Myelin Oligodendrocyte Glycoprotein (MOG) Associated Neuromylitis Optica Sprectum Disorder (NMOSD) Presenting with Isolated Absent F Wave  Shahpar Nahrir, Naim Kajtazi, Jameelah Saeedi Differential Diagnosis of Transverse Myelitis  Maureen Mealy, Daniel Becker, Scott Newsome, John Ratchford, Michael Levy, Carlos PardoVillamizar

P2.275

The Characteristics of Square Wave Jerks in Normal Subjects Michael Rosenberg, Anitha Nimma, Gita Pisupati, Neha Rane

P2.276

Temporal Aspects of Visual Perception Following Demyelination  Gabriel Shear-yashuv, Noa Raz, Shlomo Dotan, Panayiota Petrou, Adi Vaknin-Dembinsky, Netta Levin

P2.277

Lamotrigine as an Effective Pharmacotherapy for Ménière’s Disease: A Case Series  Lixin Zhang, Merika Wilson

P2.278

Diagnostic Algorithm for Approaching Patients with Suspected Giant Cell Arteritis  M. Tariq Bhatti, Mays El-Dairi, Alan Proia, Thomas Cummings

P2.279

High Resolution Optical Coherence Tomography of the Retina Demonstrates Selective Changes in Individual Retinal Layers in Parkinson’s Disease  Irene Gottlob, Anastasia Pilat, Rebecca McLean, Gail Maconachie, Viral Sheth, Yusuf Rajabally, Frank Proudlock

Due to Demyelination in INO Alessandro Serra, Margaret Skelly, Manuela Matta, Jonatan Jacobs, Mark Walker, Jeffrey Cohen, R. John Leigh

Thinning Within One Month of Presentation for Non-arteritic Anterior Ischemic Optic Neuropathy and Optic Neuritis Mark Kupersmith, Mona Garvin, Jui-Wang Wang, Mary Durbin, Randly Kardon Incidence of Visual Defects in Epileptic Children Treated with Vigabatrin Mohammadkazem Bakhshandeh Bali

P2.288 Clinical Characteristics of

Recurrent Benign Paroxysmal Positional Vertigo  Seung-Han Lee, Jong-Kyung Lee, Yun-Ju Choi, Jae-Myung Kim, Byung-Kun Kim

P2.289

Spectral Domain Optical Coherence Tomography Findings in Myotonic Dystrophy.  Maria Laura Ester Bianchi, Edoardo Abed, Guglielmo D’Amico, Marcella Masciullo, Gabriella Silvestri

P2.290

Diffusion Tensor Imaging Evaluations of Visual Pathways in Multiple Sclerosis Patients with Acute and Chronic Optic Neuritis  Ahmet Onur Keskin, Fethi Idiman, Alatas Ozkan, Emel Ada, Ali Osman Saatci, Egemen Idiman

P2.291

The Relationship Between Optical Coherence Tomographic (OCT) and Perimetric Findings in Patients with Papilledema  Mark Morrow

P2.267

Pain at Onset of Neuromyelitis Optica  Elizabeth Shuster, Reema Kola, Tori Hysko, Melanie Box

62

P2.292

2O14 Scientific Abstract Listing and Annual Meeting Information

Abnormal Electroretinogram in Neuromyelitis Optica Spectrum Disorder  Aimee Szewka, Anjali Tannan Unusual Presentation of an Isolated III Cranial Nerve Palsy from Brain Metastasis  Saiqa Choudhry, Reuben Valenzuela, Hrachya Nersesyan, Jorge Kattah Analysis of Anatomical and Functional Outcome in Three Months Follow up After a Single Intravitreal Dexamathazone (Ozurdex) Injection in Retinal Vein Occlusion Avathvadi Srinivasan Utility of Optical Coherence Tomography Measurements as a Biomarker for Systemic Lupus Erythematosus with or Without Neuropsychiatric Symptoms  Gabrielle Liu, Jacqueline Bernard

P2.300 Videoculography (VOG)

Findings with 4 Aminopyridine in Downbeat Ny (DBN): Description of 3 Cases Ana Bisonni, Guillermo Videla, Edgardo Cristiano

P2.301

Dynamic Formation of Macular Microcysts Independent of Vitreous Traction Changes  Timm Oberwahrenbrock, Ella Kadas, Wolf Lagrèze, Friedemann Paul, Alexander Brandt

P2.302

Oculomotor Dysfunction Due to Idiopathic Intracranial Hypertension and Thiamine Deficiency  Channaiah SrikanthMysore, Blanca Marky

CNS Infectious Disease: Miscellaneous P2.303 Predictive Factors of

Central Nervous Infection: Prospective Evaluation of 124 Cases with Suspicion of Meningitis.  Irene Trevino, Maria Alejandra Gonzalez Duarte, Alberto Avila-Funes

P2.304 A Retrospective Study

of Presenting Clinical and Laboratory Variables in HIV Negative Tuberculous Meningitis Patients  Brian Chisulo

Poster Session II

P2.305 NELL-2 as a Biomarker in

Diagnosing Tuberculous Meningitis: An iTRAQ Based Quantitative Proteomic Analysis of Cerebrospinal Fluid Zesong Yang

P2.306 Next-Generation

Sequencing for Pathogen Discovery in Meningoencephalitis  Michael Wilson, Erik Samayoa, Samia Naccache, Sneha Somasekar, Guixia Yu, Joseph DeRisi, Charles Chiu

P2.307

Varicella Zoster Virus Lumbar Radiculitis: A Case Report  Jazba Soomro, Hesham Allam, Aninda Acharya

P2.308 First Case of Familial

Creutzfeldt-Jakob Disease Associated with E200K Mutation in Peru: A Case Report  Jonathan Eskenazi

P2.309

Evoked Potentials in Sarcoidosis Patient  Renata Hebel, Zyta Banecka Majkutewicz

P2.310

Causes of Encephalitis in Buenos Aires: A Retrospective Cohort Study  Wilken Miguel, Mauricio Farez, Ameghino Lucía, Julieta Arena, Angel Cammarota, Martin Alejandro Nogues

Bacterial Illnesses of CNS and West Nile Virus P2.311

MRI Ventral Nerve Root Enhancement In 3 Patients Presenting with Lower Extremity Weakness Secondary to West Nile Virus  Chirag Patel, Shrikant Mishra, Bhavesh Trikamji, Brian Zipser

P2.312

The N-methyl-D-aspartate Receptor Encephalitis Mimicking Bacterial Meningitis  Jeremy Ragland, Hannah Goldstein, Barry Czeisler, Jan Claassen, Stephan Mayer, Sachin Agarwal

P2.313

Diagnostic Dilemma of Encephalomyelitis Due to Lyme Neuroborreliosis  Tiffani Stroup, Sheeraz Daudi, Heeren Patel

P2.314

Disseminated Cerebritis with Myelitis by Propionibacterium Acnes in Healthy Elderly Female  Jinsan Lee, Sung Hyuk Heo, Dae-Il Chang, Ji Hoon Lee, Seon Hee Bu

P2.315 Rhombencephalitis

Due to Listeria Monocytogens in Immunocompetent Patient  Ruchir Shah, Umang Shah, Thomas Bosley

P2.316 Syphilitic

Polyradiculoneuropathy in an Immunocompetent patient  Safaa Zahlane, Nissrine Louhab, Najib Kissani

P2.317

Widespread Leptomeningeal Involvement in Borreliosis  Carolina Maciel, Erwin Wang, Prasad Shirvalkar, Alexander Merkler, Joseph Safdieh

P2.318

Arachnoiditis Associated with an Unusual Pathogen: Aerococcus Urinae  Kara Steijlen, Shawn Vasoo, Berbari Elie, Carrie Robertson

P2.319

PATTERN of Nerve Conduction Study IN leprosy neuropathy Marcia Jardim, Robson Vital, Salim Balassiano, Mariana Hacker, Ximena Illarramendi, Euzenir Sarno

P2.320

A Case Report of CNS Whipple’s Disease  Daniel Smith

Fungi, Parasites, and Other Pathogens P2.321

A Young Woman with Seizures: A Case of Neuroschistosomiasis  Eli Zimmerman, Matthew Rose, Liangge Hsu, Alexandra Golby, Rebecca Folkerth, Sandro Santagata, Danny Milner, Shakti Ramkissoon

P2.322

A Rare Case of Isolated Intramedullary Cervical Spine Neurocysticercosis That Was Initially Misdiagnosed and Treated as Demyelinating Disease—a Case Report.  Crystal Dixon, Yazan Suradi, Rossitza Chichkova

P2.323

Meningitis Due to Cryptococcus gattii: First Reported Case of an Emerging Infectious Disease in an Immunocompetent Patient Residing in the Northeast United States  Katie Warren, Colum Amory, Ellis Tobin

P2.324

The Rhino Without Its Sugar  Jasmine Kahlon, Harneet Gahley, Niket Sonpal, Robert Graham

P2.325

Necrotizing Cryptococcal Fasciitis of the Lower Extremity: Report of a Case Following Orthotopic Cardiac Transplantation for Systemic Amyloidosis  Matthew Cykowski

P2.326

CSF and CSF:Serum Ratios of (1,3)-beta-D-glucan Are Lower in Non-Fungal CNS Pathology than Proven or Probable Fungal CNS Disease Jennifer Lyons, Kiran Thakur, Sean Zhang

P2.327

Chronic Meningitis by Histoplasma Capsulatum in Immunocompetent Patients: a Diagnostic Challenge  Bruna Silva, Alberto Martinez, Marcondes França Jr., Anamarli Nucci, Augusto Penalva-de-Oliveira

P2.328

A Case of Ciguatera Poisoning in a New York City Hospital: Learning Points for Hospitals Serving Diverse Immigrant Populations.  Neville Jadeja, Ali Haider, Reena Gottesman, Mark Kozicky, Abhinav Nafday, Kyle Kelson, Nana Jinjolava

P2.336

P2.329

P2.337

Acute Necrotizing Encephalopathy Caused by Influenza A Leading to a Rapidly Progressive Amnestic Syndrome and Coma  Brett McCray, Deborah Forst, Galen Henderson

Child Neurology and Developmental Neurology II P2.330 Trends in Outcome and

Hospitalization Charges of Pediatric Patients Admitted with Guillain Barre Syndrome Treated with Plasmapheresis in the United States. Data from Kids’ Inpatient Database (KID) 19972009  Weizhen Wang, Wenzhuan He, Nizar Souayah

P2.331

Trends in Outcome and Hospitalization Charges for Pediatric Patients Admitted with Guillain Barre Syndrome Treated with Intravenous Immunoglobulin in the United States. Data from Kids’ Inpatient Database (KID), 19972009  Kathleen Sullivan, Ankit Pahwa, Nizar Souayah

P2.332

Trends in Outcome and Hospitalization Charges of Pediatric Patients Admitted with Botulism in the United States: A Comparative Analysis Between Kids’ Inpatient Database (KID) and National Inpatient Sample (NIS)  Mohammad El-Ghanem, Ankit Pahwa, Nizar Souayah

P2.333

The Six-Minute Walk Test Captures Weakness and Gait Abnormalities in Glut 1 Deficiency Syndrome Michelle Blumenschine, Jacqueline Montes, Ashwini Rao, Aliza Alter, Kristin Engelstad, Darryl De Vivo

Regional Hippocampal Involvement in Paediatric Multiple Sclerosis: A Radial Mapping MR Study  Maria Elisa Morelli, Maria Rocca, Elisabetta Pagani, Lucia Moiola, Angelo Ghezzi, Andrea Falini, Giancarlo Comi, Massimo Filippi MHCI Immune Molecules Are Required for Developmental Synapse Elimination of the Neuromuscular Junction  Mazell Tetruashvily, Lisa Boulanger

P2.338 NextGen Sequencing as a

Tool to Assist in Diagnosis and Expedite Treatment: RAPSN Congenital Myasthenic Syndrome  Alvin Das, Dimitri Agamanolis, Bruce Cohen

P2.339

A Neonatal Case of Congenital Myasthenic Syndrome with COLQ Mutation  Matthew Imperioli, Cristian Ionita, Gyula Acsadi, Andrew Engel

Medical Student Essay Award Recipients

Tuesday April 29



First Authors stand by Posters from 7:30 a.m.–9:00 a.m.

P2.340 Voice Discrimination and Recognition in Patients with Prosopagnosic Complaints  Ran (Richard) Liu

P2.341

HAT Score Outperforms 7 other Hemorrhagic Transformation Scores  David Asuzu

P2.342

Subspecialization in Neurology: Historical Perspectives on Current Challenges  Trent Hodgson

P2.343 Probing the Interaction

of the Ipsilateral Posterior Parietal Cortex with the Premotor Cortex Using a Novel Transcranial Magnetic Stimulation Technique  Jessica Shields

P2.334

Longest Living Reported Case of Congenital Myopathy with Excess of Muscle Spindles  Julia Henry, Yael ShilohMalawsky, Stevie Rowe, Zheng Fan

P2.335

Muscular Distrophy, Mental Retardation and Deletion 2q37: A Case Report  Cristiane Rocha, Carlos Andrade, Isabel Pinheiro, Alzira Carvalho

Membership Pays! Did you know? AAN members save 50% or more on Annual Meeting Registration and program fees. Make sure your membership is up-to-date. Join or renew your AAN membership at AAN.com/membership.

Fast, Easy Registration Online  ·  AAN.com/view/AM14

63



Tuesday, April 29

Current as of 2/13/2014

Presidential Plenary Session

9:00 a.m.–12:00 p.m.

F eatures the AAN’s premier lecture awards for clinically relevant research and a presentation by a leading lecturer. Top researchers speak on some of the most significant findings in neurology in 2014. Moderator: Lisa M. DeAngelis, MD, FAAN

Chair, Science Committee

Presidential Lecture: James L. Bernat, MD, FAAN Dartmouth Hitchcock Medical Center, Lebanon, NH

Challenges to Ethics and Professionalism Facing the Contemporary Neurologist

George C. Cotzias Lecture: Endowed by Roche Pharmaceuticals. Stefan M. Pulst, MD, FAAN University of Utah, Salt Lake City, UT

Degenerative Ataxias: From Genes to Therapies

Sidney Carter Award in Child Neurology Lecture: Endowed by an anonymous donor. Darryl C. De Vivo, MD, FAAN Columbia University Medical Center, New York, NY

Rare Diseases and Neurological Phenotypes

Robert Wartenberg Lecture: David M. Holtzman, MD, FAAN Washington University School of Medicine, St. Louis, MO

Alzheimer’s Disease in 2014: Mapping a Road Forward

For Full Abstracts and Bios for Plenary Speakers Visit AAN.com/view/SearchAM

64

2O14 Scientific Abstract Listing and Annual Meeting Information

Section Topic Controversies S3  Section Topic Controversies: PFO: Aggressive Treatment or Just Aspirin

1:00 p.m.–2:30 p.m.

1:00 p.m.–1:05 p.m. Introduction  Antonio Culebras, MD, FAAN, FAHA 1:05 p.m.–1:30 pm.

PFO: Aggressive Treatment  John D. Carroll, MD

1:30 p.m.–1:55 p.m.

PFO: Just Aspirin  Steven R. Messé, MD, FAAN, FAHA

1:55 p.m.–2:05 p.m. Rebuttal  John D. Carroll, MD 2:05 p.m.–2:15 p.m. Rebuttal  Steven R. Messé, MD, FAAN, FAHA Open Discussion/Conclusion  Antonio Culebras, MD, FAAN, FAHA

Tuesday April 29

2:15 p.m.–2:30 p.m.

Obtaining Your CME and Evaluations To receive CME for education programs or scientific sessions, evaluations must be completed online or via the Annual Meeting mobile app. Wireless internet hotspots will be available at the convention center. Details will be provided prior to the meeting.

Education Program Syllabi Full text syllabi and program slides will be available electronically only—online or via the Annual Meeting mobile app. All registered attendees will receive an email notification once syllabi are available.

Fast, Easy Registration Online  ·  AAN.com/view/AM14

65



Tuesday, April 29 S4 MS and CNS Inflammatory Disease: Clinical Trials 1:00 p.m. S4.001 Rationale for Advancing Laquinimod for Progressive MS: Evidence from Large Clinical Trials in RRMS   Giancarlo Comi, Maria Pia Sormani, Gavin Giovannoni, David Ladkani, Nissim Sasson, Talia Gorfine, Volker Knappertz 1:15 p.m. S4.002 Safety and Tolerability of DelayedRelease Dimethyl Fumarate Administered as Add-On Therapy to Beta Interferons or Glatiramer Acetate in Relapsing-Remitting Multiple Sclerosis (RRMS) Patients   Vissia Viglietta, Timothy Vollmer, Ray Zhang, Mark Novas, Sarah Sheikh, Robert Fox 1:30 p.m. S4.003 Peginterferon Beta-1a May Improve Recovery Following Relapses: Data from the Pivotal Phase 3 ADVANCE Study in Patients with RelapsingRemitting Multiple Sclerosis   Bernd Kieseier, Thomas Scott, Scott Newsome, Sarah Sheikh, Serena Hung, Xiaojun You, Bjorn Sperling 1:45 p.m. S4.004 Effect of Fingolimod on Macular Volume and Retinal Nerve Fiber Layer Thickness: A One-year Longitudinal Study   Pavle Repovic, Dong Won Lee, Steven Hamilton, Eugene May, James Bowen 2:00 p.m. S4.005 Interim Analysis of 2-year Clinical Efficacy and Safety of Peginterferon Beta-1a in Patients with RelapsingRemitting Multiple Sclerosis: Data from the Pivotal Phase 3 ADVANCE Study   Aaron Deykin, Douglas Arnold, Serena Hung, Sarah Sheikh, Ali Seddighzadeh, Ying Zhu, Shifang Liu, Bernd Kieseier 2:15 p.m. S4.006 Natalizumab Treatment Improves Walking Speed in MS Patients: A Post Hoc Analysis of AFFIRM   Richard Rudick, Michael Hutchinson, Eva Havrdova, Xiaojun You, Diego Cadavid, Shibeshih Belachew 2:30 p.m. S4.007 Peginterferon Beta-1a Significantly Increases the Proportion of Patients with Freedom from Measured Disease Activity in RelapsingRemitting Multiple Sclerosis: Findings from the ADVANCE Study   Douglas Arnold, Bernd Kieseier, Sarah Sheikh, Aaron Deykin, Ying Zhu, Xiaojun You, Bjorn Sperling, Serena Hung

66

S5 Cerebrovascular Disease and Interventional Neurology: Pre-hospital, Telemedicine, and Related Topics 1:00 p.m. S5.001 The REliability of MObile TEchnologies for Acute Stroke Neuroimaging Data Interpretation: The REMOTE Study   Clotilde Balucani, Sundeep Mangla, Adrian Marchidann, Michael Szarek, Wissa Usama, Yitzchok Lederman, Charles Ramkishun, Lin Wang, Ethan Brandler, Pia Chatterjee, Susan Law, Craig Linden, Gautam Mirchandani, Diana Rojas-Soto, Daniel Rosenbaum, Hyman Shwarzberg, Richard Sinert, Mark Silverberg, Helen Valsamis, Volodymyr Vulkanov, Shahriar Zehtabchi, David Aharonoff, James Gugger, Mohit Sharma, Andrew Truong, Steven Levine 1:15 p.m. S5.002 Mobile Telestroke During Ambulance Transport Is Feasible in a Rural EMS Setting—Pilot Data from the Improving Treatment with Rapid Evaluation of Acute Stroke via Mobile Telemedicine (iTREAT) Study   Sherita Chapman, Jason Lippman, Brian Gunnell, Timothy McMurry, Prachi Mehndiratta, Donna Burns, Debra Perina, David Cattell-Gordon, Nina Solenski, Bradford Worrall, Andrew Southerland 1:30 p.m. S5.003 Tablet Computers Address Limitations of Telestroke Systems   Steven Rudolph, Susan Law, Holly Morhaim, Jill Slater 1:45 p.m. S5.004 Enrolling Patients in Ambulance Stroke Trials Using Mobile Televideo Consent: Preliminary Experience.   Amrit Ahluwalia, Sidney Starkman, Nerses Sanossian, David Liebeskind, Latisha Ali, Lucas Restrepo, May Kim-Tenser, Miguel Valdes-Sueiras, Marc Eckstein, Franklin Pratt, Samuel Stratton, Robin Conwit, Jeffrey Saver 2:00 p.m. S5.005 Strategy to a 5-Minute Door to Needle Time   Sarah Parker, Teresa Swanson-Devlin, Jan Jahnel, Clayton McNeil, Arun Talkad, Judith Beck, Deepak Nair, David Wang 2:15 p.m. S5.006 Reducing Time to Treatment—The Role of Stroke Neurologist as First Responder   Shelly Ozark, Perette Sabatino, Christine Holmstedt, Tanya Turan 2:30 p.m. S5.007 Novel Graphical Comparative Analyses of 7 Prehospital Stroke Scales   Mohit Sharma, Richard Sinert, Steven Levine, Ethan Brandler

1:00 p.m.–2:45 p.m. S6 Neuromuscular Disease: Gene Therapy

S7 Parkinson's Disease: Preclinical and Clinical Therapeutics

1:00 p.m. S6.001 Safety Profile and Pharmacokinetic Properties of Eteplirsen in the Treatment of Boys with Duchenne Muscular Dystrophy   Jihad Saoud, Jerry Mendell, Louise RodinoKlapac, Zarife Sahenk, Kandice Roush, Loren Bird, Linda Lowes, Lindsay Alfano, Ana Maria Gomez Ramirez, Sarah Lewis, Vinod Malik, Kim Shontz, Christopher Shilling, Peter Sazani, Edward Kaye

1:00 p.m. S7.001 A Large-Scale Non-Human Primate Study of the Safety and Efficacy of Neural Stem Cells Derived from Human Pluripotent Stem Cells   Ruslan Semechkin, Rodolfo Gonzalez, Ibon Garitaonandia, Alina Ostrowska, Tatiana Abramihina, Gerald Wambua, Alexander Noskov, Andrew Crain, Maxim Poustovoitov, Francesca Boscolo, Louise Laurent, Evan Snyder, Eugene Redmond

1:15 p.m. S6.002 Results at 96 Weeks of a Phase IIb Extension Study of the Exon-Skipping Drug Eteplirsen in Patients with Duchenne Muscular Dystrophy (DMD)   Edward Kaye, Jerry Mendell, Louise Rodino-Klapac, Zarife Sahenk, Kandice Roush, Loren Bird, Linda Lowes, Lindsay Alfano, Ana Maria Gomez Ramirez, Sarah Lewis, Vinod Malik, Kim Shontz, Christopher Shilling, Peter Sazani, Jihad Saoud

1:15 p.m. S7.002 TIGAR Inhibition Rescues Dopaminergic Neurons in Common Forms of Early Onset Parkinson’s’ Disease   Oliver Bandmann, Marcus Keatinge, Marc DaCosta, Heather Mortiboys, Laura Flinn

1:30 p.m. S6.003 Results of a Phase 2 Open-Label Study of ISIS-SMNRx in Patients with Infantile (Type 1) Spinal Muscular Atrophy   Richard Finkel, John Day, Claudia Chiriboga, Jiri Vajsar, Dawn Cook, Karolina Watson, Shirley Paulose, Rosangel Cruz, Jacqueline Montes, Darryl De Vivo, Mason Yamashita, Dawn McGuire, Katie Alexander, Daniel Norris, Frank Bennett, Kathie Bishop 1:45 p.m. S6.004 Future Clinical and Biomarker Development for SMT C1100, the First Utrophin Modulator to Enter Clinical Trials for Duchenne Muscular Dystrophy (DMD)   Jon Tinsley, Neil Robinson, Francis Wilson, Graeme Horne, Kay Davies 2:00 p.m. S6.005 Gene Therapy in a Model of CMT1X Neuropathy Using a Lentiviral Vector   Kleopas Kleopa, Alexia Kagiava, Stavros Bashardes, Jan Richter, Christina Christodoulou, Irene Sargiannidou 2:15 p.m. S6.006 Treatment of Experimental CIDP Using Lentivirus Transduced Dendritic Cells Expressing VIP   Mehmet Yalvac, William Arnold, Syed-Rehan Hussain, Cilwyn Braganza, K. Reed Clark, Eroboghene Ubogu, Jerry Mendell, Zarife Sahenk 2:30 p.m. S6.007 Schwann Cell-Derived Desert Hedgehog Provides a Neuroprotective Effect Against the Mechanical Stimuli from Compressive Neuropathies   Tahseen Mozaffar, James Jung, Derek Frump, Jared Su, Ranjan Gupta

2O14 Scientific Abstract Listing and Annual Meeting Information

1:30 p.m. S7.003 Isradipine Rescues Alpha-synuclein Toxicity in a Zebrafish Model of Parkinson’s Disease by Upregulating Autophagy   Mark Stahl, Shubhangi Prabhudesai, Aaron Lulla, Jeff Bronstein 1:45 p.m. S7.004 Phase-3 Clinical Trial of the Adenosine 2a Antagonist Preladenant, Given as Monotherapy, in Patients with Parkinson’s Disease   Fabrizio Stocchi, Olivier Rascol, Robert Hauser, Susan Huyck, Anjela Tzontcheva, Rachel Capece, Kenneth Wolski, Tony Ho, Peter Sklar, Christopher Lines, David Michelson, David Hewitt 2:00 p.m. S7.005 Global Long-term Registry on Efficacy and Safety of DUODOPA in Patients with Advanced Parkinson’s Disease in Routine Care (GLORIA): 12-month interim findings   Angelo Antonini, Ashley Yegin, Cornelia Preda, Werner Poewe 2:15 p.m. S7.006 Real Life Aerobic Walking Exercise in Parkinson’s Disease   Ergun Uc, Kevin Doerschug, Jeffrey Dawson, Joel Kline, Sara Newman, Warren Darling 2:30 p.m. S7.007 Rapid Levodopa Augmentation Following Inhaled CVT-301 Results in Rapid Improvement in Motor Response When Administered to PD Patients in the OFF State   Martin Freed, Donald Grosset, Paul Worth, Tanya Gurevich, Tia Defeo-Fraulini, Jerome Moore, Richard Batycky

S8 Aging, Dementia, and Cognitive and Behavioral Neurology: PET Imaging 1:00 p.m.  Presentation of Potamkin Prize for Research in Pick’s, Alzheimer’s, and Related Diseases Recipient: M. Marsel Mesulam, MD Chicago, IL

1:30 p.m. S8.003 Cerebral Amyloid Related Alterations in Neuronal Metabolism and the Contribution of Multimodal Measures of Vascular Function.   Eric McDade, Albert Kim, Timothy Hughes, Beth Snitz, Ann Cohen, Julie Price, Chester Mathis, James Becker, William Klunk, Oscar Lopez 1:45 p.m. S8.004 Integrated Analysis of (123I)FP-CIT (DaTscan; Ioflupane I123 Injection) SPECT Brain Imaging—Diagnostic Effectiveness in Patients with Movement Disorders and/or Dementia   Donald Grosset, Igor Grachev, John O’Brien, Ian McKeith, Walker Zuzana, Klaus Tatsch, Eduardo Tolosa, Paul Sherwin, Wolfgang Oertel 2:00 p.m. S8.005 Diagnostic Accuracy of Amyloid and FDG PET in Pathologically-Confirmed Dementia   Gil Rabinovici, Manja Lehmann, Howard Rosen, Pia Ghosh, Brendan Cohn-Sheehy, John Trojanowski, Mario Mendez, Harry Vinters, Dennis Dickson, Marilu Gorno-Tempini, Adam Boxer, Joel Kramer, Bruce Miller, Lea Grinberg, William Seeley, William Jagust 2:15 p.m. S8.006 FDG PET, Aging and APOE Genotype in Cognitively Normal Persons   David Knopman, Clifford Jack, Heather Wiste, Emily Lundt, Stephen Weigand, Prashanthi Vemuri, Jeffrey Gunter, Val Lowe, Kejal Kantarci, Matthew Senjem, Michelle Mielke, Rosebud Roberts, Bradley Boeve, Ronald Petersen 2:30 p.m. S8.007 Imaging Tau Pathology in vivo in FTLD: Initial Experience with (18F) T807 PET   Bradford Dickerson, Kimiko Domoto-Reilly, Daisy Hochberg, Michael Brickhouse, Michael Stepanovic, Keith Johnson

Scientific Sessions 1:00 p.m.  Presentation of Sleep Science Award Recipient: Claudia Trenkwalder, MD Kassel, Germany

1:15 p.m.  Presentation of Wayne A. Hening Sleep Medicine Investigator Award Recipient: Aleksandar Videnovic, MD, MSc Boston, MA

1:30 p.m. S9.003 Bright Light Therapy Improves Excessive Daytime Sleepiness Associated with Parkinson’s Disease   Aleksandar Videnovic, Angelica Marconi, Teresa Kuhta, Scott Miskevics, Phyllis Zee 1:45 p.m. S9.004 Distinct Innervation Patterns of the Melanin Concentrating Hormone Neurons from the Basal Forebrain Structures   Minjee Kim, Lindsay Agosstinelli, Thomas Scammell 2:00 p.m. S9.005 Antibodies Against the Cell Adhesion Molecule IgLON5 Identify a Novel Tauopathy with NREM/REM Parasomnia and Sleep Breathing Disorder   Carles Gaig, Lidia Sabater, Ellen Gelpi, Luis Bataller, Jan Lewerenz, Estefania Torres-Vega, Angeles Contreras, Bruno Giometto, Yaroslau Compta, Cristina Embid, Isabel Vilaseca, Alex Iranzo, Joan Santamaria, Josep Dalmau, Francesc Graus 2:15 p.m. S9.006 The Effects of Obstructive Sleep Apnea on Olfactory Functions   Tekeli Hakan, Murat Salihoğlu, Mustafa Kendirli, Aytuğ Altundağ, Melih Cayonu, Mehmet Şenol, Ozdag Fatih

S10 HIV, PML, and Cerebral Malaria 1:00 p.m.  Presentation of Bruce S. Schoenberg International Award in Neuroepidemiology Recipient: Devender Bhalla, PhD Limoges, France

1:30 p.m. S10.003 Delivery of Tenofovir to the Brain by Novel Nano-Vesicles for the Treatment of Neuro-HIV   Eliahu Heldman, Charles Linder, Sarina Grinberg, Mary Popov, Irwin Hollander 1:45 p.m. S10.004 Voxel Based Morphometry Findings in an Irish Cohort of HIV Positive Patients   Patricia McNamara, Janice Redmond, Peter Bede, Andrew Fagan, Colm Bergin, Arun Bokde, Colin Doherty 2:00 p.m. S10.005 Development of a Functional Scale for Progressive Multifocal Leukoencephalopathy: The NIH PML Scale   Gloria Von Geldern, Irene Cortese, Joan Ohayon, Daniel Reich, Avindra Nath 2:15 p.m. S10.006 Survival of Non-AIDS Progressive Multifocal Leukoencephalopathy   Yuri Hanada, Allen Aksamit 2:30 p.m. S10.007 Performance of Cerebrospinal Fluid (CSF) Plasmodium falciparum Histidine-Rich Protein-2 (pfHRP-2) in Prediction of Death in Cerebral Malaria   Kiran Thakur, Jimmy Vareta, Kathryn Carson, Terrie Taylor, David Sullivan, Karl Seydel

S11 Neuro Trauma, Critical Care, and Sports Neurology 1:00 p.m. S11.001 Axonal Injury, Neuroinflammation and Amyloid Pathology after Traumatic Brain Injury: Making Connections to Neurodegeneration   David Sharp, Gregory Scott, Ramlackasingh Anil, Hellyer Peter, Leech Robert, Federico Turkheimer, Paul Matthews, David Brooks 1:15 p.m. S11.002 Evolution of Traumatic Parenchymal Intracranial Hematomas (ICHs): Comparison of High Density and Low Density Components.   Sean Wilkes, Erin McCormack, Leah Harburg, Tanya Bogoslovsky, Kimbra Kenney, Dzung Pham, Ramon Diaz-Arrastia 1:30 p.m. S11.003 King-Devick Test Identifies Symptomatic Concussion in Realtime and Asymptomatic Concussion Over Time.   Priya Dhawan, Amaal Starling, Lisa Tapsell, Jennifer Adler, Steven Galetta, Laura Balcer, David Dodick 1:45 p.m. S11.004 Prognostic Value of Post-anoxic Myoclonus and Malignant EEG Patterns in Comatose Cardiac Arrest Survivors Treated with Hypothermia   Edilberto Amorim, Alexandra Popescu, Maria Baldwin, Yin Zhao, Jon Rittenberger 2:00 p.m. S11.005 Blood Biomarkers for Brain Injury in Concussed Professional Ice Hockey Players   Pashtun Shahim, Yelverton Tegner, David Wilson, Jeffrey Randall, Birgitta Kallberg, Kaj Blennow, Henrik Zetterberg 2:15 p.m. S11.006 Increased Connectivity Between the Sensorimotor Cortex and Dorsal Attention Network in Children After Mild to Moderate Traumatic Brain Injury   Sarah Risen, Anita Barber, Stewart Mostofsky, Stacy Suskauer

2:30 p.m. S9.007 Nocturnal Melatonin Regulation in Post-Traumatic Vegetative State: A Possible Role for Melatonin Supplementation?   Pietro Guaraldi, Elisa Sancisi, Giovanna CalandraBuonaura, Chiara La Morgia, Valerio Carelli, Cameli Olivia, Alberto Battistini, Pietro Cortelli, Roberto Piperno

2:30 p.m. S11.007 Development of a Medical Device for the Rapid Assessment of Concussion   Donald Weaver, Ying Tam, Christopher Barden, Ryan D’Arcy, Love Kalra, Lauren Petley, Chen Wei

S12 Cerebrovascular Disease and Interventional Neurology: Epidemiology and Risk Factors 1:00 p.m. S12.001 Ascertainment of Stroke Incidence Among Alaskan Native Populations, 2005-2009: The Alaska Native Stroke Registry   Bernadette BodenAlbala, Eric Roberts, James Allen, Lisa Bulkow, Brian Trimble 1:15 p.m. S12.002 Racial and Ethnic Disparities in Stroke. Declining Age at Time of Stroke. Analysis of the Nationwide Inpatient Sample 1988-2010   Cynthia Costa, Richard Dubinsky 1:30 p.m. S12.003 Indonesia Stroke Registry   Fenny Yudiarto, Mochammad Machfoed, Amir Darwin, Anam Ong, Muhammad Karyana, - Siswanto 1:45 p.m. S12.004 Mobile Cardiac Outpatient Telemetry Identifies Occult Atrial Fibrillation After Cryptogenic Stroke   Erin Ingala, Jenny Jara, Emily Fessler, Brett Cucchiara, Steven Messe, Michael Mullen, Allyson Prasad, Mathew Hutchinson, Scott Kasner 2:00 p.m. S12.005 Stroke Severity in Men and Women: What Proportion of the Disparity Can be Explained by Differences in Cardiovascular Risk Factors?   Karen Albright, Amelia Boehme, Bisakha Sen, Michael Mullen, Nicole Gonzales, Sean Savitz, Sheryl Martin-Schild 2:15 p.m. S12.006 Less than Ideal: Trends in Cardiovascular Health Metrics Among US Stroke Survivors, NHANES 1988-2010   Michelle Lin, Daniela Markovic, Bruce Ovbiagele, Amy Towfighi 2:30 p.m. S12.007 Incidence and Predictors of Unprovoked Seizures After Stroke   Ettore Beghi

S13 MS and CNS Inflammatory Disease: MRI Atrophy Measures and Correlations 1:00 p.m. S13.001 A Gender-based 3T MRI Comparison of Brain and Spinal Cord Involvement in Relapsing-Remitting Multiple Sclerosis   Antonia Ceccarelli, Gloria Kim, Jennifer Miller, Shahamat Tauhid, Tanuja Chitnis, Mohit Neema, Rohit Bakshi 1:15 p.m. S13.002 Thalamic Atrophy in RIS: MRI Evidence of Early CNS Neurodegeneration   Christina Azevedo, Eve Overton, Sankalpa Khadka, Jessica Buckley, Shuang Liu, Mehul Sampat, Orhun Kantarci, Christine Lebrun Frenay, Aksel Siva, Darin Okuda, Daniel Pelletier 1:30 p.m. S13.003 Thalamic Dysfunction Is Associated with Fatigue in Patients with Multiple Sclerosis: A Graph Theory Study   Massimo Filippi, Paola Valsasina, Alvino Bisecco, Alessandro Meani, Laura Parisi, Maria Josè Messina, Bruno Colombo, Andrea Falini, Giancarlo Comi, Maria Rocca 1:45 p.m. S13.004 Clinical and Paraclinical Parameters Associated with Brain Atrophy in Newly Diagnosed MS Patients.   Bertrand Bourre, Christine Clerc, Frederic Blanc, Vincent Noblet, Stephane Kremer, Julien Lamy, Jean-Paul Armspach, Baradi Brice, Helene Zephir, Olivier Outteryck, Marc Debouverie, Sophie Pittion, Patrick Vermersch, Jerome De Seze 2:00 p.m. S13.005 Magnetic Resonance Imaging Correlates of Clinical Outcomes in Early Multiple Sclerosis   Amir Hadi Maghzi, Nisha Revirajan, Laura Julian, Rebecca Spain, Ellen Mowry, Jacqueline Marcus, Shuang Liu, Chengshi Jin, Ari Green, Charles McCulloch, Daniel Pelletier, Emmanuelle Waubant 2:15 p.m. S13.006 Proportion of Patients with Brain Volume Loss Comparable to Healthy Adults in Fingolimod Phase 3 Multiple Sclerosis Studies   Nicola De Stefano, Davorka Tomic, Dieter Haering, Allitia Dibernardo, Gordon Francis, Ernst-Wilhelm Radue, Ludwig Kappos 2:30 p.m. S13.007 Spinal Cord Lesion Load Is Associated With Disability Independently From Atrophy In Multiple Sclerosis   Hugh Kearney, Rebecca Samson, Marios Yiannakas, Claudia WheelerKingshott, Olga Ciccarelli, David Miller



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Tuesday April 29

S9 Sleep



Tuesday, April 29 I5 Revolution of Genetic Tools and the Impact on Neurology

1:00 p.m.–5:00 p.m.

Coordinators: Petra Kaufmann, MD and Mark F. Mehler, MD, FAAN Invited Speaker Session:  1:00 p.m.–3:30 p.m. 1:00 p.m.–1:25 p.m.

Advances in Epigenetics and their Implications for Understanding and Treating Neurological Disorders  Mark Mehler, MD, FAAN

1:25 p.m.–1:50 p.m.

How Gene Networks and Systems Biology Informs Our Understanding of Nervous System Disease  Daniel Geschwind, MD, PhD

1:50 p.m.–2:15 p.m.

New Genetic Tools and Their Impact on the Diagnosis of Neuromuscular Disorders  Kenneth Fischbeck, MD

2:15 p.m.–2:40 p.m.

Clinical Whole-Exome Sequencing in the Diagnosis of Mendelian Disorders of the CNS  Arthur Beaudet, MD

2:40 p.m.–3:05 p.m.

Using Genomics in Routine Clinical Care  Teri Manolio MD, PhD

3:05 p.m.–3:30 p.m.

Advances in Genetics and Impact on the Treatment of Neurological Disease  Beverly Davidson, PhD

Poster Rounds:  3:30 p.m.–4:30 p.m. I5-1.001 Exome Sequencing

Identifies PINCH2 Mutations in Early Onset Autosomal Recessive LGMD with Severe Cardiomyopathy and Triangular Tongues  Jodi Warman Chardon, Amanda Smith, John Woulfe, Kawan Rakhra, Elena Pena Fernandez, Chandree Beaulieu, Jeremy Schwartzentruber, Cynthia Hawkins, Matthew Harms, Mei Zhang, Jacek Majewski, Dennis Bulman, Kym Boycott, David Dyment

I5-1.002 Genetic and Neuroanatomic

Associations in Sporadic Frontotemporal Lobar Degeneration  Corey McMillan, Jon Toledo, Brian Avants, Philip Cook, Elisabeth Wood, Eunran Suh, David Irwin, John Powers, Christopher Olm, Lauren Elman, Leo McCluskey, Gerard Schellenberg, Virginia Lee, John Trojanowski, Vivianna Van Deerlin, Murray Grossman

I5-1.003 Transcript Profiling Analysis

of Alzheimer’s Disease Brains. Mariet Allen, Daniel Serie, Michael Walsh, Sun Zhifu, Saurabh Baheti, Fanggeng Zou, High Seng Chai, Curtis Younkin, Julia Crook, Vernon Pankratz, Minerva Carrasquillo, Asha Nair, Sumit Middha, Sooraj Maharjan, Thuy Nguyen, Li Ma, Kimberly Malphrus, Sarah Lincoln, Gina Bisceglio, Christopher Kolbert, Jin Jen, Ronald Petersen, Neill Graff-Radford, Dennis Dickson, Steven Younkin, Yan Asmann, Nilufer Taner

I5-1.004 Novel Mutation in VCP

Causes Charcot-Marie-Tooth Type 2 (CMT2) Phenotype  Shawna Feely, Michael Gonzalez, Chris Weihl, Michael Shy, Stephan Zuchner

I5-1.005 GCH1 Heterozygous

I5-1.008 TMEM106B Is a Genetic

I5-1.006 Structural and Functional

I5-1.009 Expression QTL Studies in

Mutation Identified by Whole-ExomeSequencing as a Treatable Condition in a Patient Presenting with Progressive Spastic Paraplegia  Zheng Fan, Robert Greenwood, Ana Felix, Yael ShilohMalawsky, Myra Roche, Kristy Crooks, Jonathan Berg, James Evans Implications of Modeling Non Synonymous Mutations in Patients with SCN1A-related Seizure Disorders  Mu Gao, Hongyi Zhou, Izabela Karbassi, Khalida Liaquat, Daniel Fischer, Jeffrey Skolnick, Joseph Higgins

I5-1.007 The Dissection of

High-Penetrance Variants in Extended Late-onset Alzheimer Disease Families by Whole-Exome Sequencing  Martin Kohli, Brian Kunkle, Adam Naj, Li-San Wang, Kara Hamilton, William Perry, Regina Carney, Patrice Whitehead, John Gilbert, Eden Martin, Gary Beecham, Jonathan Haines, Gerard Schellenberg, Stephan Zuchner, Margaret Pericak-Vance

Modifier of Frontotemporal Lobar Degeneration with C9orf72 Hexanucleotide Repeat Expansions  Alice Chen-Plotkin, Michael Gallagher, Eunran Suh, Murray Grossman, Lauren Elman, Leo McCluskey, John Trojanowski, Virginia Lee, Vivianna Van Deerlin LOAD and PSP Brains by Next-generation RNA Sequencing  Nilufer Taner, Chen Wang, Minerva Carrasquillo, Mariet Allen, Curtis Younkin, Daniel Serie, Vernon Pankratz, Thuy Nguyen, Li Ma, Kimberly Malphrus, Sarah Lincoln, Ronald Petersen, Neill Graff-Radford, Steven Younkin, Dennis Dickson, Yan Asmann

Data Blitz:  4:30 p.m.–5:00 p.m. 4:30 p.m.

I5-2.001

Late-onset Alzheimer Disease Neuropathology Genomic Screen Identifies Novel Loci for Neuritic Plaque and Other AD Neuropathology Features  Gary Beecham, Kara Hamilton, Gerard Schellenberg, Margaret Pericak-Vance, Thomas Montine

4:35 p.m.

I5-2.002

4:40 p.m.

I5-2.003

The TREM2 Variant p.R47H Is a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis  Matthew Harms, Janet Cady, Erica Koval, Bruno Benitez, Craig Zaidman, Jennifer Jockel-Balsarotti, Peggy Allred, Robert Baloh, John Ravits, Ericka Simpson, Stanley Appel, Alan Pestronk, Alison Goate, Timothy Miller, Carlos Cruchaga TIGAR Inhibition Rescues Dopaminergic Neurons in Common Forms of Early Onset Parkinson’s Disease  Oliver Bandmann, Marcus Keatinge, Marc DaCosta, Heather Mortiboys, Laura Flinn

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4:45 p.m.

I5-2.004

Investigation of Transcriptional Regulation at the Alzheimer’s Disease Risk Loci.  Michaela Kachadoorian, Mariet Allen, Aditya Karhade, Lester Manly, Fanggeng Zou, High Seng Chai, Curtis Younkin, Julia Crook, Vernon Pankratz, Minerva Carrasquillo, Asha Nair, Sumit Middha, Sooraj Maharjan, Thuy Nguyen, Li Ma, Kimberly Malphrus, Sarah Lincoln, Gina Bisceglio, Christopher Kolbert, Jin Jen, Ronald Petersen, Neill Graff-Radford, Steven Younkin, Dennis Dickson, Nilufer Taner

2O14 Scientific Abstract Listing and Annual Meeting Information

4:50 p.m.

I5-2.005

Spinal Muscular Atrophy Phenotype Is Ameliorated Either by SMN Increase or Modulation of Secondary Cell Death Events with RNA Therapy  Giulietta Riboldi, Monica Nizzardo, Chiara Simone, Federica Rizzo, Margherita Ruggieri, Serena Pagliarani, Gianna Ulzi, Sabrina Salani, Andrea DalMas, Monica Bucchia, Emanuele Frattini, Giulia Stuppia, Francesca Magri, Nereo Bresolin, Franco Pagani, Giacomo Comi, Stefania Corti

Integrated Neuroscience Sessions I6  Peripheral Neuropathies

1:00 p.m.–5:00 p.m.

Coordinators: P. James B. Dyck, MD, FAAN and Tahseen Mozaffar, MD, FAAN Invited Speaker Session:  1:00 p.m.–3:30 p.m. 1:00 p.m.–1:10 p.m. Introduction  Tahseen Mozaffar, MD, FAAN 1:10 p.m.–1:35 p.m.

Role of Anti-Ganglioside Antibodies in Neuropathies, Including Latest Advances  Kazim Sheikh, MD

1:35 p.m.–2:00 p.m.

Post-Surgical Inflammatory Neuropathies  P. James B. Dyck, MD, FAAN

2:00 p.m.–2:25 p.m.

Role of Exome and Next Generation Sequencing in Peripheral Neuropathies  Christopher J. Klein, MD

2:25 p.m.–2:50 p.m.

Neuropathy in Diabetes and the Metabolic Syndrome  James W. Russell, MD, MS, FRPC, FAAN

2:50 p.m.–3:15 p.m.

Update on Acquired Inflammatory Demyelinating Polyradiculopathies  Kenneth C. Gorson, MD

3:15 p.m.–3:30 p.m.

Panel Discussion

Poster Rounds:  3:30 p.m.–4:30 p.m. Transporter 1 (MCT1) Is Critical for Regeneration in Peripheral Nerves Brett Morrison, Akivaga Tsingalia, Sylvain Lengacher, Luc Pellerin, Pierre Magistretti, Jeffrey Rothstein

I6-1.002 Characteristics of

Muscle Cramps in Patients with Polyneuropathy  Katzberg Hans, Sarah Maxwell, Seint Kokokyi, Hamid Ebadi, Ari Breiner, Vera Bril

I6-1.003 Gene Therapy in a Model

I6-1.004 Peripheral Edema and

Weight Gain in Adult Patients with Painful Diabetic Peripheral Neuropathy (DPN) Receiving Gabapentin Enacarbil (GEn) or Pregabalin Enrolled in a Randomized Phase 2 Trial  Anne Calkins, Joseph Shurman, Mark Jaros, Richard Kim, Gwendoline Shang

I6-1.005 Deletion of Sarm1 Gene

Protects Against Paclitaxel-induced Peripheral Neuropathy  Ahmet Hoke, Elliot Turkiew, Nicole Reed

of CMT1X Neuropathy Using a Lentiviral Vector  Kleopas Kleopa, Alexia Kagiava, Stavros Bashardes, Jan Richter, Christina Christodoulou, Irene Sargiannidou

I6-1.006 Peripheral Nerve

Amyloidosis: Phenotype, Natural History, and Autonomic Dysfunction in Inherited Versus Acquired Subtypes Adam Loavenbruck, Wolfgang Singer, Paola Sandroni, Michelle Mauermann, P. James B. Dyck, Christopher Klein, Phillip Low

I6-1.007 DS-5565 for the Treatment of Diabetic Peripheral Neuropathic Pain: Randomized, Double-blind, Placebo- and Active Comparator-controlled Phase II Study  Aaron Vinik, Uma Sharma, Karen Feins, Ching Hsu, Domenico Merante

I6-1.009 Is IVIg Therapy Warranted

Tuesday April 29

I6-1.001 Monocarboxylate

in Progressive Lower Motor Neuron Syndromes without Conduction Block?  Neil Simon, Gretchen Ayer, Catherine Lomen-Hoerth

I6-1.010

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Sera Alter Regulators of Schwann Cell Differentiation  Abhijeet Joshi, Ilja Bobylev, Christian Ritter, Andre Heinen, Helmar Lehmann

I6-1.008 Neuropathy Associated

with Nondiabetic Obesity  J. Singleton, Eric Volckmann, Timothy Graham, Albert Smith

Data Blitz:  4:30 p.m.–5:00 p.m. 4:30 p.m.

I6-2.001

Schwann Cell-Derived Desert Hedgehog Provides a Neuroprotective Effect Against the Mechanical Stimuli from Compressive Neuropathies  Tahseen Mozaffar, James Jung, Derek Frump, Jared Su, Ranjan Gupta

4:35 p.m.

I6-2.002

4:40 p.m.

I6-2.003

Neuropathy Improvement Following Peripheral Blood Stem Cell Transplantation for POEMS Syndrome.  Chafic Karam, Christopher Klein, Angela Dispenzieri, Jayawant Mandrekar, P. James B. Dyck, Anita D’Souza, Michelle Mauermann

4:45 p.m.

I6-2.004

Induced Pluripotent Stem Cell Based Models of CMT1A and HNPP  Robert Baloh, Irina Epifantseva, Kevin Kim, Shaughn Bell, Sharon Carmona, Sharday Grant, Megan Simpkinson, Matthew Harms, Dhruv Sareen, AKMG Muhammad

4:50 p.m.

I6-2.005

Treatment of Experimental CIDP Using Lentivirus Transduced Dendritic Cells Expressing VIP  Mehmet Yalvac, William Arnold, Syed-Rehan Hussain, Cilwyn Braganza, K. Reed Clark, Eroboghene Ubogu, Jerry Mendell, Zarife Sahenk

Quantification of Sciatic Nerve Pathology in Inherited Neuropathies via Magnetization Transfer MRI  Richard Dortch, Lindsey Dethrage, Audra Hamilton, John Gore, Seth Smith, Jun Li



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Tuesday, April 29 P3  Poster Session III First Authors stand by Posters from 5:00 p.m.–6:30 p.m.

3:00 p.m.–6:30 p.m.

Poster Discussion Session: Epilepsy/Clinical Neurophysiology (EEG) Utilizing a guided tour format, topic experts will lead attendees around the ten posters in the poster discussion session and facilitate questions with poster authors during the 90-minute author stand-by time.

P3.001

Antibodies to GABAa Receptor Associate with Seizures, Status Epilepticus, and Remove the Receptors from Synapses  Mar Petit, Thais Armangue, Xiaoyu Peng, Rebecca Davis, Lindsey McCracken, Rita Balice-Gordon, Francesc Graus, Josep Dalmau

P3.002

Is Generic Drug Quality as Good as Brand? Surveillance Testing of Marketed Lamotrigine Batches and Comparison to Brand Soundarya Vaithianathan, Siddarth Raman, Wenlei Jiang, Tricia Ting, Maureen Kane, James Polli

P3.003

Characteristics of Traumatic Fractures in Patients with Epilepsy  Franziska Herpich, Kenneth Walsh, Neha Vijayvargiya, Wayne Satz, Mercedes Jacobson

P3.004

Utility of Selective Posterior Cerebral Artery Amobarbital Testing in Surgical Evaluation for Patients with Temporal Lobe Epilepsy  Courtney Schusse, Wil Schultz, Caleb Pearson, Steve Chung

P3.005

Utility of CT Perfusion (CTP) Imaging in Seizures: A Retrospective Analysis and Literature Review Aunali Khaku, Vishunmurthy Hedna, Michael Waters

P3.006

Where and How Are the Initial Antiepileptic Drugs Administered to Children Who Develop Refractory Status Epilepticus? Results from the Pediatric Status Epilepticus Research Group (pSERG)  Ivan Sanchez Fernandez, Nicholas Abend, Satish Agadi, Ravindra Arya, Rajit Basu, Jessica Carpenter, Kevin Chapman, Nathan Dean, William Gaillard, Tracy Glauser, Howard Goodkin, Michele Jackson, Mohamad Mikati, Katrina Peariso, Geetanjali Rathore, Robert Tasker, Alexis Topjian, David Turner, Angus Wilfong, Korwyn Williams, Tobias Loddenkemper

P3.007

The Experience of the GENESS International Consortium to Accelerate Discovery of New Epilepsy Genes  Antonio Escueta, Maria Alonso, Marco Medina, Reyna Duron, Julia Bailey, Iris Martinez-Juarez, Miyabi Tanaka, Donsheng Bai, Aurelio Jara-Prado, Adriana Ochoa, Jesus Machado-Salas, Thiery Grisar, Kazuhiro Yamakawa, Elza Targas Yacubian, Laura Guilhoto, Jose Serratosa, Christopher Patterson, Joan Spellman, Jenny Wight, Yu-Chen Lin, Sumia Aftab

P3.010

Reversible Intraoperative Neurophysiologic Monitoring Changes Associated with Surgical Retraction Leslie Lee, Sungho Cho, Viet Nguyen, Gary Steinberg, Steven Chang, Robert Dodd, Stephen Ryu, Jaime Lopez

P3.008

Serum IL6, IL1β And IL1Ra Levels in Patients with Epilepsy Irem Fatma Uludag, Tarik Duksal, Yasar Zorlu, Feriha Ozkaya, Guldal Kirkali

P3.009

Review of Aggression in Adults and Adolescents in Perampanel Phase III Epilepsy Clinical Trials Antonia LoPresti, Alan Ettinger, Haichen Yang, Betsy Williams, Sharon Zhou, Randi Fain, Antonio Laurenza

NEW! e  Poster Session: Neuromuscular and Clinical Neurophysiology (EMG) I The ePoster session will feature a selection of posters to be presented digitally, rather than in the traditional format. Authors will be able to take advantage of the format to highlight compelling visual features such as images and videos. See poster map on page 47 for location.

P3.011

Discriminant Value of 18FDG-PET in Amyotrophic Lateral Sclerosis  Adriano Chio, Marco Pagani, Andrea Calvo, Cristina Moglia, Flavio Nobili, Piercarlo Fania, Silvia Morbelli, Consuelo Valentini, Antonio Canosa, Angelina Cistaro

P3.012

Cytoplasmic Redistribution of Mutant TDP-43 in a BAC Based Mouse Model of Amyotrophic Lateral Sclerosis  Kevin Talbot, David Gordon, Ruxandra Mutihac, Javier AlegreAbarrategui, Lucy Farrimond, Ben Davies, Richard Wade-Martins

P3.013

Real-time Video Microscopy to Assess Pathologic Leukocyte-Endothelial Cell Interactions at the Human BloodNerve Barrier In Vitro: A Tool to Guide Specific Drug Therapy for Peripheral Neuropathies  Eroboghene Ubogu

P3.014

Medical Marijuana Utilization and Perceived Therapeutic Value in Patients with ALS  Jacob Kaufman, Kelly Almasy, Ashley Boller, Nabila Dahodwala, Lauren Elman, Mary Kelley, Leo McCluskey

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P3.015

Looking for an Early Diagnosis in a Late Onset Pompe Disease High Risk Population: a LOPED Study Olimpia Musumeci, Giancarlo la Marca, Severo Pagliardini, M Spada, Cesare Danesino, Giacomo Comi, Elena Pegoraro, Giovanni Antonini, Gianni Marrosu, Rocco Liguori, Lucia Morandi, Maurizio Moggio, Roberto Massa, Sabrina Ravaglia, Antonio Di Muzio, Corrado Angelini, Massimiliano Filosto, Paola Tonin, Giuseppe Di Iorio, Serenella Servidei, Gabriele Siciliano, Tiziana Mongini, Antonio Toscano

P3.016

Plasmapheresis Enables Robust Micro-Dystrophin Expression Following Gene Transfer in Subjects with Pre-Existing Immunity  Louis Chicoine, Chrystal Montgomery, Thomas Preston, Danielle Griffin, William Bremer, K. Reed Clark, Zarife Sahenk, Christopher Walker, Jerry Mendell, Louise Rodino-Klapac

P3.018

Quantitative Ultrasound Provides Insight into How Electrical Impedance Myography Measurements Are Impacted by Disease.  Irina Shklyar, Tom Geisbush, Aleksandar Mijailovic, Amy Pasternak, Nicole Visyak, Heather Szelag, Jim Wu, Craig Zaidman, Basil Darras, Seward Rutkove

P3.019

Anti-Growth Factor Receptor 3 Antibodies Identify a Sub-Group of Sensory Neuropathy Patients JeanChristophe Antoine, Boutahar Nadia, Véronique Rogemond, Jerome Honnorat, Jean-Phillippe Camdessanche

P3.017

Characterization of B-cell Subsets in MuSK Myasthenia Gravis Jeff Guptill, John Yi, Donald Sanders, Amanda Guidon, Sara Sparks, Robyn Osborne, Janice Massey, Vern Juel, Lisa HobsonWebb, Kent Weinhold

2O14 Scientific Abstract Listing and Annual Meeting Information

P3.020

Bone Mineral Content as Measure of Bone Health in Ambulatory Boys with Duchenne Muscular Dystrophy  Cuixia Tian, Meilan Rutter, Lindsey Hornung, Jane Khoury, Lauren Miller, Jean Bange, Brenda Wong

Poster Session III P3.021

A randomized Controlled Trial Comparing Botulinum Toxin Type A Xeomin® and Dysport® for Treatment of Primary Axillary Hyperhidrosis Francesca Pastorelli, Roberto Michelucci, Rosaria Plasmati

P3.022

Multiplex Testing of AntiNeural Autoantibodies  Lars Komorowski, Kristin Rentzsch, Sandra Saschenbrecker, Bianca Teegen, Christian Probst, Winfried Stoecker

P3.023

Brain Lactate in Patients with Autosomal Dominant Adult-Onset Leukodystrophy (ADLD): a 1H-MR Spectroscopy Study.  Stefano Zanigni, Caterina Tonon, Claudia Testa, Rossana Terlizzi, Laura Gramegna, Claudio Bianchini, Pietro Guaraldi, Giovanna Calandra Buonaura, Pietro Cortelli, Raffaele Lodi

P3.035

Neurological Complications After Kidney Transplantation Kateryna Kurako, Nancy Rosales, Ramon Lugo

P3.050

P3.036

P3.051

Relationship Between Bone Mass and Muscle Weakness in Chronic Neurological Diseases  Maria Gutierrez, Gabriel Eduardo Rodriguez, Domingo Garcea, Raul Rey, Sandra Lepera, Ercolano Monica, Drnovsek Monica, Kerzberg Eduardo, SIlva Berenice

P3.037

Functional Brain Dimorphism in Psychopath Offenders Evidenced by QEEG Analysis  Ana Calzada-Reyes, Alfredo Alvarez Amador, Lídice Galán-García

P3.038

The Vulpian-Bernhardt Syndrome in the Clinical Spectrum of Amyotrophical Lateral Sclerosis: A Case Report and Literature Review. Armando Jordan, Marie-Catherine Boll

P3.039

P3.024

Trigeminal Neuralgia to a Tibial tumour; Four Degrees of Separation Laura Williams, Ronan Killeen, Thomas Crotty, Michael Hutchinson, Christopher McGuigan

P3.025

P3.040

Prognosis of Treated Neurosarcoidosis  Allen Aksamit, Blake Fechtel, Tyler VanDyck, Andrew Tseng Spinal Cord Compression Associated with a Systemic IgG4 Disease  Mohamad Ezzeldin, Ahmad Shawagfeh, Vicki Schnadig, Robert Smith, Xiang Fang

P3.026

Conversion of New Active MRI Lesions at 6 Months to T1 Hypointense ‘Black Holes’ at 12 Months in RRMS Subjects from the GALA Study Robert Zivadinov, Joshua Steinerman, Volker Knappertz, Hadas Barkay, Omar Khan

P3.027

Olfactory Dysfunction in Chagas’ Disease  Fidias Leon-Sarmiento, Edgardo A Bayona, Carlos V Rizzo-Sierra, Alicia Garavito, Maria Fernanda Campos, Richard Doty

P3.028

Multiple Sclerosis Comorbidity Study  Robert Simpson

P3.029

Paclitaxel Affects Axonal Mitochondria in a Murine Model of Chemotherapy-Induced Peripheral Neuropathy  Ilja Bobylev, Abhijeet Joshi, Christian Ritter, Ahmet Hoke, Helmar Lehmann

P3.030

Using Rapid Reaching Tasks to Reveal the Underlying Mechanisms of Decision Making in Humans  Maria Khami

P3.031

Acute Focal Dystonia Heralding the Diagnosis of Type 2 Diabetes Mellitus  Alok Sachdeva, Deepak Gulati, Michael Devereaux

P3.032

Primary Angiitis of the Central Nervous System presented with Tumor-like lesion: A Case Report  Yasaman Kianirad, Shyam Prabhakaran

P3.033

Utility of Computed Tomogram of Head for Patients with Altered Mental Status  Sanjeev Sivakumar, Zakhar Serkin, Camelia Arsene, Ramesh Madhavan, Navid Seraji-Bozorgzad

P3.034

A Case of Adult Langerhans Cell Histiocytosis Presenting as Isolated Central Diabetes Insipidus: A Powerful Tool to Detect the Hypophyseal and Extrahypophyseal Involvement Junko Maeda, Junwa Kunimatsu, Sohtaro Mine, Kaoru Aishima, Atsuto Yoshizawa

The European Union Is worth saving  Anne Hoeritzauer, Gavin McDonnell, Marjo Van Der Knaap

Neural Repair and Neurorehabilitation: Clinical P3.041

Hyperbaric Oxygen Therapy Versus Antiepileptic Drugs in the Control of Late Post Traumatic Non Convulsive Epilepsy Refractory to Phenytoin Sherif Abd Elmonem, Soliman Tahon, Ann Abd Elkader, Akram Fayed

P3.042

A Compilation of Spasticity Studies Evaluating Onabotulinumtoxin A  Payal Patel, Aubrey Manack

P3.043

Treating Neglect by Body Movements: A Case Report and Follow-up Study  Amit Chaudhari, Kara Pigott, Peii Chen, A. Barrett

P3.044

A Preliminary Examination of Psychological and Neuropsychological Outcomes in Patients with Mild Traumatic Brain Injury  Shannon McNally, Katherine Lopez, Sarah Levy, John Dsurney, Leighton Chan

P3.045

Functional Motor Recovery In Stroke Survivors—Determinants in a Stroke Unit in Sub-Saharan Africa. Frank Imarhiagbe

P3.046

Cognitive Training Program for Memory/Executive Reasoning Deficits in Adults with Traumatic Brain Injury Barbara Fisher, Danielle Garges

P3.047

Alterations in Muscle Coordination Following Robot-Assisted Gait Training in Hemiparetic Stroke: A Case Series  Adam Thrasher, Stanley Fisher

P3.048

Comparison of Headache in OEF/OIF Veterans with Traumatic Brain Injury (TBI) against Controls Matched for Age, Sex, Race and Deployment Time  James Couch, Kenneth Stewart

P3.049

Higher Coated-Platelets in Patients with Mild Traumatic Brain Injury Correlate with Lower Cognitive Screening Performance  Calin Prodan, Andrea Vincent, George Dale



Patient Registry of Outcomes in Spasticity (PROS) Care World Alberto Esquenazi, Nathaniel Mayer, Stella Lee Fatigue and Functional MRI in Multiple Sclerosis: A Quantitative Coordinate-based Activation Likelihood Estimation Meta-analysis  Radu Tanasescu, Cris Constantinescu, Ali Manouchehrinia, Dorothee Auer, Christopher Tench

P3.052

White Matter Disease Ratings in Right Hemisphere Stroke Annapoorna Bhat, Marianne Kim, Anne Foundas, Peii Chen

P3.053

The Effects of Salsa Dance on Gait and Balance in Multiple Sclerosis  Rosalind Mandelbaum, Elizabeth Triche, Susan Fasoli, Albert Lo

P3.054

Prospective Assessment of Falls Among People with Multiple Sclerosis and Healthy Matched Controls Rajarshi Mazumder, Charles Murchison, Michelle Cameron

P3.055

Brain-Computer Interface Driven Functional Electrical Stimulation System for Overground Walking: A Case Report  Christine King, Colin McCrimmon, Po Wang, Cathy Chou, Zoran Nenadic, An Hong Do

P3.056

Improvement of Gait Following Walking Based Long-term aerobic Endurance Exercise In Mildly Disabled MS Patients  Stephan Schmidt, Marc Wonneberger

P3.057

The Potential Diagnostic Approach to Characterize Peripheral Nerve Injury Using 4-AP  Kuang-Ching Tseng, John Elfar

P3.058

Action Observation Therapy Modifies Structural Brain Plasticity in Healthy Adult Individuals  Paolo Preziosa, Maria Rocca, Roberto Gatti, Melissa Petrolini, Roberta Messina, Gabriele Salini, Silvia Fumagalli, Andrea Falini, Giancarlo Comi, Massimo Filippi

P3.059

VR-based Training Using Wii Fit Improve Obstacle Crossing Performance and Dynamic Balance in Patients with Parkinson Disease  Yingyi Liao, Yea-Ru Yang, Ray-Yau Wang

Movement Disorders: Clinical Features of Parkinson’s Disease P3.060

Parkinson’s Disease Among Mexican Americans Aged 74 Years and Older in the Southwestern United States  Nicte Mejia, Sunshine Rote, NaiWei Chen, Kyriakos Markides, Soham Al Snih

P3.061

Recurrent Falls in Parkinson Disease (PD)  Abraham Lieberman, Rohit Dhall, Aman Deep, Narayanan Krishnamurthi, Naomi Salins, Di Pan

P3.062

Auditory Processing Abilities of Parkinson Disease Patients Robert Folmer, Jay Vachhani

P3.063

Levodopa and Posture— Quantification of Trunk Performance in Parkinson’s Disease  Felix Benninger, Alexander Khlebtovsky, Yaniv Roditi, Eldad Melamed, Ruth Djaldetti

P3.064

Tactile Cueing Improves Motor Performance and Motor-Cognitive Integration in Parkinson’s Disease Vladimir Ivkovic, Stanley Fisher, William Paloski

P3.065

Carotid Artery Thickening and Neurocirculatory Abnormalities in De Novo Parkinson Disease  Joong-Seok Kim, Yoon-Sang Oh, Kwang-Soo Lee, In-Uk Song, Yeong-In Kim, Dong-Won Yang, Ja-Seong Koo, David Goldstein

P3.066

Effect of Parkinson Disease Age of Onset on Family History Nicholas Hac, Madaline Harrison, G. Wooten, Matthew Barrett

P3.067

Discordance Between Medication Apps and Needs of Patients with Parkinson’s Disease Anupama Divakaruni, Melissa Armstrong, Ann GruberBaldini, Lisa Shulman

P3.068

Neuroprotection by Sex Steroid Hormones in Parkinson’s Disease  Kara Smith, Nabila Dahodwala

Tuesday April 29

General Neurology II

P3.069

Gender and Dopaminergic Medication Treatment in Early Parkinson Disease  Chizoba Umeh, Adriana Pérez, Erika Augustine, Rohit Dhall, Richard Dewey, Zoltan Mari, David Simon, Anne Marie Wills, Chadwick Christine, Jay Schneider, Oksana Suchowersky

Movement Disorders: Assessing Parkinson’s Disease P3.070

Motion Sensor Dyskinesia Assessment During Activities of Daily Living  Christopher Pulliam, Michelle Burack, Joseph Giuffrida, Thomas Mera

P3.071

Walking Capacity (WalkCap) Measured by Six-Minute Walk (6MW) Does Not Demonstrate Fatigue in Patients with Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS),and Parkinson Disease (PD)  Mohammed Sanjak, Laura Morgan, Ashely Simpson, Scott Holsten, Mark Hirsch, Danielle Englert, Sanjay Iyer, Jill Conway, Michael Kaufman, Elena Bravver, Urvi Desai, Priscilla Russo, Benjamin Brooks

P3.072

Quantitative Motor Assessment in Parkinson’s Disease (PD) with the MovAlyzeR® Digital Writing Tablet  Alexander Pantelyat, Rebecca Freedman, Stephanie Pawlowski, Adhithi Kesari, Jayne Wilkinson, John Duda, James Morley

P3.073

Dynamic Fall-risk Predictors in Parkinson’s Disease  Ashutosh Mani, Kari Dunning, Travis Larsh, Cyndy Cox, Amit Shukla, Amit Bhattacharya, Fredy Revilla

P3.074

Objective Assessment of Electro-acupuncture Benefit for Improving Balance and Gait in Patients with Parkinson’s Disease  Hong Lei, Nima Toosizadeh, Michael Schwenk, Scott Sherman, Stephen Karp, Saman Parvaneh, Esther Esternberg, Bijan Najafi

P3.075

Low Health Literacy: An Under-Recognized Obstacle in Parkinson’s Disease  Jori Fleisher, James Minger, Whitney Fitts, Nabila Dahodwala

Fast, Easy Registration Online  ·  AAN.com/view/AM14

71



Tuesday, April 29 P3.076

Avoiding Ventricular Transgression During DBS Surgery: A Quality Improvement Intervention  Meagan Bailey, Roy Strowd, Jessica Tate, Ihtsham Haq, Stephen Tatter, Adrian Laxton, Mustafa Siddiqui

P3.077

Sex Differences in Clinical Features of Early, Treated Parkinson Disease  Erika Augustine, Rohit Dhall, Adriana Perez, Chizoba Umeh, Oksana Suchowersky

P3.089

Can Neuronal Voltage-gated Potassium Channels be Associated with Parkinsonism?  Hardik Doshi, Edwin George, Natalya Shneyder

Cerebrovascular Disease and Interventional Neurology: Clinical Management P3.090

Is There a Relationship Between Social Phobia and Parkinson’s Disease?  Christina Saldivar, Guillermo Moguel-Cobos

Factors Associated with 30-day Readmission Rate Among Stroke Patients from 2009-2012 at Two Tertiary Level Hospitals in Metro Portland Area  Amit Kansara, Tamela Stuchiner, Elizabeth Baraban, Archit Bhatt

P3.079

Pronounced Task Specific Writing Tremor in Parkinson’s Disease  Katelyn Smith, Aws Alawi, Joanna Ramiro, Pratap Chand

P3.091

Movement Disorders: Other Parkinsonian Disorders

P3.092

P3.078

P3.080

Olfactory Impairment and Other Features of Parkinson Disease That Predict Persistent Drug-Induced Parkinsonism  James Morley, Stephanie Pawlowski, Alexander Pantelyat, Adhithi Kesari, Ivy Maina, John Duda

P3.081

Long-term Levodopa Use in Normal Substantia Nigra Cases Michele Rajput, Ali Rajput, Christopher Robinson, Alexander Rajput

P3.082

The Entity of Parkinsonism and Associated Lipomatosis Maria Stamelou, Una-Marie Sheerin, Nicholas, W Wood, Kailash Bhatia

P3.083

REM Sleep and Motor Symptoms in Parkinson’s Disease: A Cross Sectional Analysis  Abhimanyu Mahajan, Charlene Gamaldo, Rachel Marie Salas, Gregory Pontone, Chizoba Umeh, Liana Rosenthal, Arita McCoy, Zoltan Mari

P3.084

Mild Parkinsonian Signs Are a Risk Factor for Falls  Nabila Dahodwala, Chinwe Nwadiogbu, Whitney Fitts, Helen Partridge, Jason Karlawish

P3.085

A Family with Corticobasal Degeneration, Parkinson’s Disease, Amyotrophic Lateral Sclerosis, and Dementia  Shinsuke Fujioka, Monica Sanchez Contreras, Audrey Strongosky, Pawel Tacik, Bradley Boeve, A Stoessl, Matthew Baker, Rosa Rademakers, Dennis Dickson, Zbigniew Wszolek

P3.086

Three New Families with Perry Syndrome from Distinct Parts of the World—Novel Mutation and Successful Treatment Attempt of Respiratory Insufficiency  Pawel Tacik, Shinsuke Fujioka, Owen Ross, Wolfdieter Springer, Fabienne Fiesel, Felipe Pretelt, Camilo Castañeda Cardona, Alexa Kidd, Michael Hlavac, Anthony Raizis, Michael Okun, Zbigniew Wszolek

P3.087

Vascular Parkinsonism in a Tertiary Care Stroke Prevention Clinic: Prevalence and Development of a New Screening Strategy  Herbert Manosalva Alzate, Thomas Jeerakathil, Maher Saqqur, Richard Camicioli, Oksana Suchowersky

P3.088 WITHDRAWN

72

Etiologies of Neurologic Deterioration in the First 30 Days Following Ischemic Stroke  Iftekhar Ahmed, Kirstin Hirni, Sakher Albadarin, Neeta Duggal Vertigo and Dizziness in Anterior Circulation Cerebrovascular Disease: A Systematic Review  Yun Zhou, Seung-Han Lee, Georgios Mantokoudis, Ali Saber Tehrani, Sarah Ying, Kevin Kerber, Yu-Hsiang Hsieh, Karen Robinson, Daniel Hanley, David Zee, David Newman-Toker

P3.093

Risk Factors for Ischemic Stroke Mortality  Claudia Alonzo, Maria Zurru, Laura Brescacin, Ariel Luzzi, Luis Camera, Gabriel Waisman, Edgardo Cristiano

P3.094

Relation of Serial Hemodynamic and Autonomic changes in Acute Ischemic Stroke to Stroke Type, Location and Outcome.  Arunodaya Gujjar, Deepali Jaju, Jacob Poovathur, Mohan Dikshit, Abdullah Al-Asmi

P3.095

Cerebral Infarction Occurrence in Settings of Acute Traumatic Injury. Analysis of a Prospective Multicenter Trial  Tanya Mohindroo, Malik Adil, Sheharyar Minhas, Adnan Qureshi

P3.096

Nonmydriatic Ocular Fundus Photography Among Patients with Focal Neurologic Deficits in an Emergency Department (ED)  Beau Bruce, Laurel Vuong, Praneetha Thulasi, Valerie Biousse, David Wright, Nancy Newman

P3.097

Peripheral Artery Disease in Patients with Ischemic Stroke: A Cross Sectional Observational Study Attiya Rahman, Syed Akhtar, Qaiser Jamal

P3.098

Factors Affecting the Acceptance of Decompressive Craniectomy in Patients with a Malignant Middle Cerebral Artery Infarction  Seungnam Son, Jiho Hong, Dae Seob Choi, Min Kyun Oh, Soo-Kyoung Kim, Heeyoung Kang, Ki-Jong Park, Nack-Cheon Choi, Oh-Young Kwon, Byeong Hoon Lim

P3.099

NIH Stroke Scale Change Correlates with Length of Stay in Intensive Care Unit Stroke Patients Prashanth Krishnamohan, Qian Fan, Michael Dobbs

3:00 p.m.–6:30 p.m. Cerebrovascular Disease and Interventional Neurology: tPA P3.100

Stroke Outcomes and Usage of IV Alteplase during Pregnancy in the Nationwide Inpatient Sample 20052010  Sarah Song, Bichun Ouyang, Taylor Knopf, James Conners, Shawna Cutting, Vivien Lee, Laurel Smit, Elena Kuklina

P3.101

Baseline Body Temperature: Paradoxical Association with Severity and Non-Modification of Treatment Benefit in the NINDS TPA Stroke Trials  Seo Hyun Kim, Jeffrey Saver

P3.102

Collateral Circulation Recruitment and Failure in Acute Ischemic Stroke Patients Treated with IV rTPA. Leonard Yeo, Prakash Paliwal, Hock Luen Teoh, Chee Seong Seet, Eric Ting, Bernard Chan, Rahul Rathakrishnan, Jonathan Ong, Vijay Sharma

P3.103

Direct and Indirect Cost Burden of Stroke Mimics Post Intravenous Tissue Plasminogen Activator (IV-tPA): A Single Center Study  Nitin Goyal, Shailesh Male, Ameer Al Wafai, Ramin Zand

P3.104

Is the Use of r-tPA in Mild Stroke Patients Cost-Effective? Gregory Guzauskas, Er Chen, Pooja Khatri, Peter Sandercock, Darren Tayama, David Veenstra

P3.112

Vessel Wall Characteristics of Bilateral and Unilateral Moyamoya Syndrome using High Resolution Magnetic Resonance Imaging  Russell Cerejo, Ferdinand Hui, Stephen Jones, Emmanuel Obusez, Ken Uchino

P3.113

Thyrotoxic Graves’ Disease and Moyamoya-like Vasculopathy in Latino Patients: A Case Series  Nirav Shah, Gillian Gordon-Perue, Gustavo Ortiz, Alejandro Forteza

P3.114

Cephalometric Features of Moyamoya Disease: A Case Control Study  Waqas Gilani, Sarwat Gilani, Malik Adil, Adnan Qureshi

P3.115

The Association and Treatment of Distal PICA Aneurysms with Posterior Fossa Arteriovenous Malformation: A Case Series  David Case, Takamasa Higashimori, Joshua Seinfeld

P3.116

Obesity in a Young Adult Stroke Population  Jina Youn, Joni Clark

P3.117

Erythropoetin associated Posterior Reversible Encephalopathy Syndrome  Rajanandini Muralidharan, Madhurima Anne, Elissa Fory, Wirkowski Elizabeth

P3.118

P3.105

Reversible Cerebral Vasoconstriction Syndrome in Association with Fingolimod Use  Scott Belliston, Nancy Hammond, Jayashree Sundararajan

P3.106

Cerebrovascular Disease and Interventional Neurology: Primary and Comprehensive Stroke Centers

Effect Of Education to Hospital Staff on Efficiency of Acute Stroke Thrombolysis  Dheeraj Khurana, Anish Hirachan, Ashish Bhalla, Sudesh Prabhakaran Etiologies of Neurologic Deterioration Following Intravenous Thrombolysis for Acute Ischemic Stroke.  Alex Perchuk

P3.107

HAT Score External Validity: A Predictor of Hemorrhagic Transformation After Intravenous Thrombolysis Elizeu Neto

P3.108

Determine the Gender Differences in Outcome Following Thrombolysis in Ischemic Stroke. Zabeend Mahuwala, Kaustubh Limaye, Anand Patel, Archana Hinduja, Rajan Patel

P3.109

HAT Score Outperforms 7 Other Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated with Thrombolysis  David Asuzu, Karin Nystrom, Janet Halliday, Charles Wira, David Greer, Joseph Schindler, Kevin Sheth

Cerebrovascular Disease and Interventional Neurology: Large Vessel Nonatherosclerotic Arteriopathies

P3.119

Automated Datamining to Create Stroke Database and Concurrent ‘Managed Alerts’ for Comprehensive Stroke Center Metrics  Ramesh Madhavan, Fnu Abhishek, Connie Parliament, Megan Dietrich, Navid Seraji-Bozorgzad, Pratik Bhattacharya

P3.120

90 Day Outcomes in Stroke/ Transient Ischemic Attack Patients Receiving Initial or Follow-up Care in a Comprehensive Outpatient Stroke Center  Vernice Bates, Erica Westphal, Michelle Rainka, Francis Gengo

P3.121

The Impact of a Stroke Prevention Clinic After Discharge for TIA/ Stroke: University Hospitals Case Medical Center Comprehensive Stroke Center Experience  Tanzila Shams, Kathleen Vickers, Richard Jung, Cathy Sila

P3.122

Quantifying Cerebral Collaterals in Carotid Artery Dissection May Help Stratify Stroke Risk. Andrew Southerland, John Gaughen, Jr., Timothy McMurry, Max Wintermark, Jennifer Majersik, Bradford Worrall

Rates of In-hospital Adverse Events and Discharge Outcomes Among Ischemic Stroke Patients Admitted to Joint Commission Primary Stroke Centers in United States  Saqib Chaudry, Taqi Zafar, Mohammad Afzal, Mohammad Umair, Mohammad Owais, Gautam Sachdeva, Malik Adil, Vishal Jani, Syed Hussain, Adnan Qureshi

P3.111

P3.123

P3.110

Ischemic Stroke and Cervical Artery Dissection. Risk Factors and Functional Outcome in a Single Tertiary Care Hospital: The Clinica Alemana Stroke Registry (RECCA), 1997-2003  Violeta Diaz, Maria Vicuña, Jose Fernandez, Marcela Valenzuela, Pablo Lavados

2O14 Scientific Abstract Listing and Annual Meeting Information

Characteristics of Certified Stroke Center Programs Led by Vascular Neurologists  Lucas Ramirez, Aaron Krug, Joshua Perese, Gregory Gasparian, Suzie Kazaryan, Nerses Sanossian

Poster Session III

P3.124

Failed Bedside Dysphagia Screen Predicts Pneumonia Treatment in Acute Stroke: A Resident Quality Initiative Project in a JC-Certified Primary Stroke Center  Mohamed-Ali Babi, Mark Gorman, Christopher Commichau, Sharon Kenney, Lakshmi Boyle, Mary Comeau, Steve Hulsey

P3.125

Hydration Practices for the Acute Stroke Patient in an Academic, Certified Stroke Center  Mona Bahouth, Argye Hillis, Rebecca Gottesman

P3.126

Leadership of Certified Stroke Center Programs  Lucas Ramirez, Aaron Krug, Joshua Perese, Gregory Gasparian, Suzie Kazaryan, Nerses Sanossian

P3.127

Compare the Weekend Effect in Telestroke and Primary Stroke Center.  Zabeend Mahuwala, Anand Patel, Kaustubh Limaye, Archana Hinduja, Nicolas Bianchi, Rajan Patel

P3.128

Differences in Payment for Inpatient Transient Ischemic Attack Care Between Stroke Center and Non-StrokeCenter Hospitals  Shuhan He, Sebina Bulic, Suzie Kazaryan, Steven Cen, May Kim, May Kim, William Mack, Nerses Sanossian

MS and CNS Inflammatory Disease: Tools for Clinical Assessment and Therapeutic Response P3.129

Multiple Sclerosis Performance Test: A Reliable, Sensitive, and Meaningful Tool to Quantify MS Related Disability  Richard Rudick, Deborah Miller, Francois Bethoux, Stephen Rao, JarChi Lee, Darlene Stough, Christine Reece, David Schindler, Jay Alberts

P3.130

Multiple Sclerosis Documentation System MSDS3D— Innovative Management of Patients with Multiple Sclerosis  Judith Eisele, Raimar Kern, Suhrbier Alexander, Lars Großmann, Thorsten Schultheiss, Tjalf Ziemssen

P3.131

Psychometric Properties of the MSIS-29 and Factors Predicting Score Changes in Clinical Trials: An Analysis of Data from the SELECT Study Glenn Phillips, Jane Castelli-Haley, Shien Guo, Irina Proskorovsky, Jacob Elkins

P3.132

The Multiple Sclerosis Performance Test: An Innovative Approach to Measuring MS-Related Manual Dexterity Impairment  Francois Bethoux, Richard Rudick, Deborah Miller, Stephen Rao, Jar-Chi Lee, Darlene Stough, Christine Reece, David Schindler, Jay Alberts

P3.133

Multiple Sclerosis Decision Model (MSDM): A Multifactorial Model to Monitor Treatment Response and Disease Course in Relapsing Remitting Multiple Sclerosis  Martin Stangel, Iris Katharina Penner, Boris Kallmann, Carsten Lukas, Bernd Kieseier, Ralf Gold

P3.134

Plasticity-Based Cognitive Remediation in Multiple Sclerosis (MS)  Leigh Charvet, Maria Amella, William Scherl, Dana Serafin, Emily Taub, Patricia Melville, Lauren Krupp

P3.135

Kinect-based Gait Analysis in Patients with Multiple Sclerosis Janina Behrens, Karen Otte, Sebastian MansowModel, Alexander Brandt, Friedemann Paul

P3.136

The Turkish Multiple Sclerosis Walking Scale (MSWS-12v2T): Is it the Same Measure as the Original Version?  Hussein Dib, Yusuf Tamam, Murat Terzi, Jeremy Hobart

P3.137

Patient Preferences in the Choice of Disease Modifying Drugs for Multiple Sclerosis  Arnfin Bergmann, Michael Lang, Christian Ludger Bischoff, Petra Schicklmaier, Hans-Dieter Nolting, Guido Schiffhorst, Julian Rellecke, Erika Kunz

P3.138

Identifying Individuals with Multiple Sclerosis in an Electronic Medical Record  Kristen Krysko, Noah Ivers, Jacqueline Young, Paul O’Connor, Karen Tu

P3.139

Assessment of Disability in Multiple Sclerosis Using the Kinect-Camera System: A Proof-of-Concept Study Marcus D Souza, Christian Kamm, Jessica Burggraaff, Prejaas Tewarie, Ben Glocker, Jonas Dorn, Thomas Vogel, Cecily Morrison, Abigail Sellen, Matthias Machacek, Peter Chin, Bernard Uitdehaag, Antonio Criminisi, Frank Dahlke, Chris Polman, Ludwig Kappos

P3.140

Multiple Sclerosis Performance Test: Patients Express High Satisfaction with the Application Deborah Miller, Jar-Chi Lee, Francois Bethoux, Stephen Rao, Jay Alberts, David Schindler, Darlene Stough, Christine Reece, Richard Rudick

P3.141

Cultural Adaptation and Evaluation of the Psychometric Properties of the MSTCQ© “MS Treatment Concerns Questionnaire” Spanish Language Version  Elvira Munteis, Navarro Guillermo, Jose Meca La Llana, Asuncion Maestre Martinez, Ángel Sempere, Julia Gracia, Antonio Pato

P3.142

Validating an Electronic Method for Prospective Fall Counting in People with MS  Ashley Downs, Charles Murchison, Rajarshi Mazumder, Michelle Cameron

P3.143

The Role of G-tubes In Decreasing UTIs in a Cohort of Patients with Advanced MS  Kathleen Healey, Neil Jouvenat, Mac McLaughlin, Lyndsay HartWann, Kristine Rutledge, Rana Zabad

P3.144

Graded Response Analysis of the MSIS-29 in Clinical Trial Participants with Relapse-Remitting Multiple Sclerosis  Glenn Phillips, Elizabeth Danzie, Kathy Wyrwich

P3.145

Comparing Disability of Multiple Sclerosis Cohort in a Tertiary Clinic and Volunteer North American Research Committee on Multiple Sclerosis Registry Using Patient-Derived Multiple Sclerosis Severity Score  Ariel Antezana, Joseph Herbert, Eric Chamot, Gary Cutter, Amber Salter, Ilya Kister



P3.146

Relationship Between Immunological Markers and Short-term Brain Volume Changes in Patients with Relapsing-Remitting Multiple Sclerosis Receiving Interferon Beta-1a Michael Dwyer, Robert Zivadinov, Yazhong Tao, Xin Zhang, Cheryl Kennedy, Niels Bergsland, Deepa Ramasamy, Jackie Durfee, David Hojnacki, Bianca Weinstock-Guttman, Brooke Hayward, Fernando Dangond, Silva Markovic-Plese

P3.153

P3.147

P3.154

Correlations Between Immunological Biomarkers and Conventional and Advanced MRI Measures Following Interferon Beta-1a Treatment for Relapsing-Remitting Multiple Sclerosis  Silva Markovic Plese, Yazhong Tao, Xin Zhang, Michael Dwyer, Cheryl Kennedy, Niels Bergsland, Deepa Ramasamy, Jacqueline Durfee, David Hojnacki, Bianca Weinstock-Guttman, Brooke Hayward, Fernando Dangond, Robert Zivadinov

P3.148

Burden of Multiple Sclerosis on Caregivers and Patients and Degree of Satisfaction with Current Treatment: The MS-Feeling Study  José Meca, Maria Del Mar Mendibe Bilbao

MS and CNS Inflammatory Disease: Clinical Trials Outcomes P3.149

Clinical Trial of Helminthinduced Immunomodulatory Therapy (HINT 2) in Relapsing-Remitting Multiple Sclerosis  John Fleming, Leslie Hartman, Jane Maksimovic, Sara Nace, Christopher Luzzio, Monica Koehn, Anna Ritter, Todd Risa, Benjamin Lawler, Andrea Maser, Pamela Mundt, Loren Rolak, Thomas Cook, Aaron Field, Zsuzsanna Fabry

P3.150

Safety and Efficacy of Teriflunomide for up to 9 Years in Relapsing Forms of Multiple Sclerosis: Update of the TEMSO Extension Trial  Mark Freedman, Jerry Wolinsky, Giancarlo Comi, Ludwig Kappos, Tomas Olsson, Aaron Miller, Myriam Benamor, Deborah Dukovic, Jinjun Liang, Philippe Truffinet, Paul O’Connor

P3.151

Safety and Efficacy of Siponimod (BAF312) in Patients with Relapsing-Remitting Multiple Sclerosis: Results from Dose-blinded Extension Phase of BOLD Study  Ludwig Kappos, Olaf Stuve, Hans Hartung, Mark Freedman, David Li, Bernhard Hemmer, Peter Rieckmann, Xavier Montalban, Tjalf Ziemssen, Brian Hunter, Sophie Arnould, Erik Wallstrom, Krzysztof Selmaj

P3.152

24-month Interim Results of PANGAEA: A 5-year Registry Study Evaluating Long-term Safety, Efficacy and Pharmacoeconomic Data of German Multiple Sclerosis Patients on Fingolimod Therapy  Tjalf Ziemssen, Maria DiazLorente, Alexandra Fuchs, Christian Cornelissen

A Multinational, Multicenter, Randomized, Double-Blind, ParallelGroup, Active-Control Study to Evaluate the Efficacy, Safety, and Tolerability of Oral Laquinimod 0.6mg or 1.2mg QD versus IFNβ-1a in Patients with Relapsing Remitting Multiple Sclerosis Hans-Peter Hartung, Frederik Barkhof, Oscar Fernandez, Jeremy Hobart, Gavin Giovannoni, Maria Pia Sormani, Yuval Dadon, Nissim Sasson, Volker Knappertz Efficacy and Safety of Anti LINGO-1 for the Treatment of Relapsing Forms of Multiple Sclerosis: Design of the Phase 2 SYNERGY Trial  Diego Cadavid, Glenn Phillips, Tuan Dong-Si, Jonathan Tran, Lei Xu

P3.155

Pilot Trial of Recombinant Human Growth Hormone for Remyelination in Multiple Sclerosis: Current Status and Preliminary Safety Analysis Muriel Stoppe, Barbara Ettrich, Eva Thomae, Juergen Kratzsch, Karl-Titus Hoffmann, Dirk Hasenclever, Florian Then Bergh

P3.156

Fingolimod Efficacy and Safety in an African-American Patient Subgroup from FREEDOMS II  Patricia Coyle, Bruce Cree, Philippe Cabre, Matilde Inglese, Jai Perumal, Xiangyi Meng, Peter Chin, Ron Hashmonay, Omar Khan

P3.157

Predicting Confirmed Disability Progression in MS: Importance of Early on-Treatment MRI Changes on Modeling the CombiRx Trial Database  Florent Lalys, Leorah Freeman, John Lincoln, Flavia Nelson, Ponnada Narayana, Stacey Cofield, Tarah Gustafson, Gary Cutter, Fred Lublin, Jerry Wolinsky

P3.158

Alemtuzumab Improves Visual Outcomes Versus Subcutaneous Interferon Beta-1a in Patients with Active RelapsingRemitting Multiple Sclerosis (RRMS) Who Relapsed on Prior Therapy: Analysis from the CARE-MS II Study Jennifer Graves, Laura Balcer, Jeffrey Palmer, David Margolin, Steven Galetta

P3.159

Effect of Delayed-Release Dimethyl Fumarate on Freedom from Measured Clinical and Neuroradiological Disease Activity in Relapsing-Remitting Multiple Sclerosis (RRMS) Patients: An Integrated Analysis of DEFINE and CONFIRM  Eva Havrdova, Ralf Gold, Robert Fox, Ludwig Kappos, J. Theodore Phillips, Annie Zhang, Nuwan Kurukulasuriya, Sarah Sheikh, Vissia Viglietta, Gavin Giovannoni

P3.160

4-Year Follow-up of DelayedRelease Dimethyl Fumarate Treatment in Relapsing-Remitting Multiple Sclerosis (RRMS): Integrated Magnetic Resonance Imaging (MRI) Outcomes from DEFINE, CONFIRM, and the ENDORSE Extension Study  Douglas Arnold, Robert Fox, Ralf Gold, Eva Havrdova, Ludwig Kappos, Tarek Yousry, Ray Zhang, Minhua Yang, Vissia Viglietta, Sarah Sheikh, David Miller

Fast, Easy Registration Online  ·  AAN.com/view/AM14

73

Tuesday April 29



First Authors stand by Posters from 5:00 p.m.–6:30 p.m.



Tuesday, April 29 P3.161

Effect of Ceralifimod (ONO-4641), a Sphingosine-1-Phosphate Receptor-1 and -5 Agonist, on Magnetic Resonance Imaging Outcomes in Patients with Multiple Sclerosis: Interim Results from the Extension of the DreaMS Study Amit Bar-Or, Frauke Zipp, Matthew Scaramozza, Timothy Vollmer, Bryan Due, Karthinathan Thangavelu, Tanya Fischer, Krzysztof Selmaj

P3.162

Effect of Delayed-Release Dimethyl Fumarate on Health-Related Quality of Life in Relapsing-Remitting Multiple Sclerosis (RRMS) Patients According to Prior Therapy: An Integrated Analysis of the Phase 3 DEFINE and CONFIRM Studies Ludwig Kappos, Robert Fox, Ralf Gold, Mariko Kita, J. Theodore Phillips, Sujata Sarda, Lixian Zhong, Timothy Niecko, Nuwan Kurukulasuriya, Gavin Giovannoni

P3.163

Disability Progression in Multiple Sclerosis Patients Treated with Natalizumab in the Long-term STRATA Study  Andrew Goodman, Ludwig Kappos, Fred Lublin, Shibeshih Belachew, Madalina Chirieac, Fiona Forrestal, Petra Duda

P3.164

Patients Free of Clinical MS Activity in TEMSO and TOWER: Pooled Analyses of Two Phase 3 Placebo-Controlled Trials  Tomas Olsson, Giancarlo Comi, Mark Freedman, Aaron Miller, Jerry Wolinsky, Philippe Truffinet, Steven Cavalier, Deborah Dukovic, Paul O’Connor, Ludwig Kappos

P3.165

Sustained Improvement in Disability Outcomes with Alemtuzumab in Active Relapsing-Remitting Multiple Sclerosis Patients Who Participated in CARE-MS II: Three-year Follow-up Gavin Giovannoni, David Margolin, Jeffrey Palmer, Joseph Herbert

P3.166

Categorical Change in T2 Lesion Volume and Clinical Outcomes in the Phase III FREEDOMS and its Extension Study, Evaluating Fingolimod in Patients with Relapsing-Remitting Multiple Sclerosis  Douglas Jeffery, Elisabetta Verdun Di Cantogno, Daniela Meier, Michael Meinel, Peter Chin, William Camu

P3.167

A Stabilized Release Neuropeptide exhibits efficacy in a Phase II Double Blind Placebo Controlled Clinical Trial of Secondary Progressive Multiple Sclerosis  Christopher Moore, Jeffery Vernes, Deirdre McIntosh, Syed Haq

P3.168

Oral versus Intravenous High Doses of Methylprednisolone in Multiple Sclerosis Relapses, a Double Blinded Randomised Controlled Trial (COPOUSEP): Results at 1 Month (Primary End Point)  Emmanuelle Le Page, David Veillard, David Laplaud, Rasha Wardi, Christine Lebrun Frenay, Fabien Zagnoli, Sandrine Wiertlewski, Veronique Deburghgraeve, Marc Coustans, Gilles Edan

P3.169

Subgroup and Sensitivity Analyses of the Primary Endpoint from the Peginterferon Beta-1a ADVANCE Study: A Pivotal Phase 3 Study in Patients with Relapsing-Remitting Multiple Sclerosis  Bernd Kieseier, Douglas Arnold, Ying Zhu, Shifang Liu, Serena Hung, Aaron Deykin, Sarah Sheikh

74

P3.170

A Phase I/II Study of Pixantrone in Patients with an Aggressive RelapsingRemitting or SecondaryProgressive Multiple Sclerosis (PIXAMS)  Richard Gonsette, Gilles Edan, Marc Debouverie, Christian Sindic, Jean Christophe Ferre

P3.171

Clinical Efficacy of DelayedRelease Dimethyl Fumarate in Minority Patients with Relapsing-Remitting Multiple Sclerosis (RRMS): An Integrated Analysis of the Phase 3 DEFINE and CONFIRM Studies  Michael Hutchinson, J. Theodore Phillips, Macaulay Okwuokenye, Nuwan Kurukulasuriya, Ralf Gold, Robert Fox

P3.172

FDA-Approved Phase I Clinical Trial of Autologous Neural Progenitors Injected Intrathecally in Multiple Sclerosis  Violaine Harris, Daniel Koffler, Sydney Chirls, Saud Sadiq

P3.173

4-Year Follow-up of DelayedRelease Dimethyl Fumarate Treatment in Relapsing-Remitting Multiple Sclerosis (RRMS): Integrated Clinical Efficacy Data From DEFINE, CONFIRM, and the ENDORSE Extension Study  Ralf Gold, Ted Phillips, Amit Bar-Or, Michael Hutchinson, Ludwig Kappos, Ray Zhang, Minhua Yang, Vissia Viglietta, Sarah Sheikh, Robert Fox

P3.174

Efficacy of Fingolimod in Pre-treated Patients with Disease Activity: Pooled Analyses of FREEDOMS and FREEDOMS II  Niklas Bergvall, Nicolaos Sfikas, Peter Chin, Davorka Tomic, Philipp Von Rosenstiel, Ludwig Kappos

P3.175

Comparative Efficacy of Switching to Natalizumab Versus Switching to Interferon-Beta or Glatiramer Acetate After On-treatment MS Relapse Using Propensity-Matched Registry Data Maria Trojano, Timothy Spelman, Tomas Kalincik, Annie Zhang, Heinz Wiendl, Ludwig Kappos, Shibeshih Belachew, Robert Hyde, Freek Verheul, Francois Grand-Maison, Helmut Butzkueven

P3.176

The PREFERMS Study: Evaluating Real-world Patient Retention on Oral Fingolimod Compared with Injectable Disease Modifying Therapies in RelapsingRemitting Multiple Sclerosis Nadia Tenenbaum, Lesley Schofield, Xiangyi Meng, Ralph Kern

P3.177

Evaluation of Immunogenicity in Multiple Sclerosis Patients Treated with Daclizumab-HYP During the SELECT and SELECTION Clinical Trials Lakshmi Amaravadi, Alvydas Mikulskis, Manjit McNeill, Katherine Riester, Marianne Sweetser, Jacob Elkins, Gavin Giovannoni

P3.178

Assessing a Scoring System to Predict Disease Activity in Patients with Multiple Sclerosis: Post Hoc Analyses of Data from Clinical Trials of Subcutaneous Interferon Beta-1a  Mark Freedman, Ali-Frédéric Ben-Amor, Ernesto Aycardi, Delphine Issard, Florence Casset-Semanaz

3:00 p.m.–6:30 p.m. P3.179

Lymphocyte Count Reductions in Relapsing-Remitting Multiple Sclerosis (RRMS) Patients Treated with DelayedRelease Dimethyl Fumarate: An Integrated Analysis of the Placebo-Controlled Studies  Robert Fox, Ralf Gold, J. Theodore Phillips, Krzysztof Selmaj, Kartik Raghupathi, Huixing Yuan, John O’Gorman, Mark Novas, Vissia Viglietta, Nuwan Kurukulasuriya

P3.189

P3.180

P3.190

Consistent Reduction in the Annualized Rate of Brain Volume Loss Across Phase 3 Core and Extension Trials of Fingolimod in Relapsing Multiple Sclerosis  Ernst-Wilhelm Radue, Till Sprenger, Peter Chin, Daniela Piani Meier, Nicolaos Sfikas, Frederik Barkhof

P3.181

Lymphocyte Counts Do Not Predict Risk of Subsequent Relapse or Disability Accumulation in AlemtuzumabTreated Relapsing-Remitting Multiple Sclerosis Patients: An Analysis of the CARE-MS Studies  Alasdair Coles, Jeffrey Palmer, David Margolin

P3.182

Early and Consistent Reduction in Relapses among Patients with Relapsing-Remitting Multiple Sclerosis Receiving Subcutaneous Interferon Beta-1a: A Post-Hoc Analysis of PRISMS Data  Mark Cascione, Carol Gaines, Juanzhi Fang, Fernando Dangond, Aaron Miller

P3.183

Patient-Reported Outcomes After Therapy Switch to Fingolimod: Post-hoc Subgroup Analysis of the EPOC Study  Barry Singer, Mark Gudesblatt, Neetu Agashivala, Stan Li, Simrat Randhawa, Kevin McCague, Luigi Barbato

P3.184

Diagnosing Multiple Sclerosis: Analysis of the Output from an Adjudication Panel in the Setting of a MS Diagnostic Assay Clinical Trial  Benjamin Greenberg, Nancy Monson, Douglas Bigwood, Eric Eastman

P3.185

Four-year Expanded Disability Status Scale (EDSS) Outcomes in Patients Treated with Fingolimod in the Phase 3 and Extension Trial Program  Bruce Cree, Jeffrey Cohen, Peter Chin, Shannon Ritter, Daniela Piani Meier, Philipp von Rosenstiel, Ludwig Kappos

P3.186

Natalizumab in Patients with Early MS: The STRIVE Study Roumen Balabanov, Jai Perumal, Robert Fox, Denise Campagnolo, Emese Dian, Stefan Lanker, Jiankang Liu, Mary-Jean Fanelli

P3.187

Reduction in Brain Atrophy with Extended Daclizumab HYP Treatment: Results of SELECT and the SELECT Extension Study  Ernst-Wilhelm Radue, Dusan Stefoski, Ralf Gold, Manjit McNeill, Katherine Riester, Jacob Elkins

P3.188

Decrease in T1 Black Hole Volume Over 2 Years of Daclizumab HighYield Process Treatment  Jacob Elkins, Eva Havrdova, Manjit McNeill, Katherine Riester, Ernst-Wilhelm Radue

2O14 Scientific Abstract Listing and Annual Meeting Information

Clinical Efficacy of DelayedRelease Dimethyl Fumarate in RelapsingRemitting Multiple Sclerosis (RRMS) Patients with Highly Active Disease: An Integrated Analysis of the Phase 3 DEFINE and CONFIRM Studies Michael Hutchinson, Annie Zhang, Minhua Yang, Ray Zhang, Nuwan Kurukulasuriya, Robert Fox, Ralf Gold Do MRI Lesions Predict MS Relapses?  Nancy Richert, Fiona Forrestal, Sophia Lee, Petra Duda

P3.191

The Vitamin D to Ameliorate Multiple Sclerosis (VIDAMS) Trial Pavan Bhargava, Sonya Steele, Sandi Cassard, Elizabeth Sugar, Daniel Pelletier, Emmanuelle Waubant, Ellen Mowry

P3.192

Pharmacokinetics of Vitamin D in Multiple Sclerosis Patients and Healthy Controls.  Sonya Steele, Pavan Bhargava, Jacqueline Marcus, Nisha Revirajan, Emmanuelle Waubant, Ellen Mowry

P3.193

Efficacy Benefits of Fingolimod 0.5 mg Once Daily in Patients Previously Treated with Glatiramer Acetate: Pooled Analysis of the Phase 3, Placebo-controlled FREEDOMS and FREEDOMS II Studies in Relapsing Multiple Sclerosis Douglas Jeffrey, Ernst-Wilhelm Radue, Goeril Karlsson, Hanzhe Zheng, Philipp Von Rosenstiel, Ludwig Kappos

P3.194

Pharmacokinetics and Pharmacodynamics of Peginterferon Beta1a in Patients with Relapsing-Remitting Multiple Sclerosis: Data from the Pivotal Phase 3 ADVANCE Study  Xiao Hu, Yue Cui, Joleen White, Ying Zhu, Aaron Deykin, Ivan Nestorov, Serena Hung

P3.195

Mediation of the Effect of Laquinimod on Disability Progression in Relapsing-Remitting Multiple Sclerosis (RRMS)  Giancarlo Comi, David Ladkani, Timothy Vollmer, Maria Pia Sormani, Yulia Sidi, Volker Knappertz

P3.196

MRI Correlates of Disability: Neuroimaging Substudy at 20 Years in the Ongoing US Glatiramer Acetate Open-label Extension Study  Omar Khan, Fen Bao, Megha Shah, Gautam Ramesh, Christina Caon, Carla Santiago, Zahid Latif, Rimma Aronov, Imad Zak, Yulia Sidi, Scott Kolodny

Aging, Dementia, and Cognitive and Behavioral Neurology: Clinical Aspects P3.197

Validation of a Simple Model for Prediction of Disease Duration in Persons Presenting with Alzheimer Disease: “ Tell Me Doc, How Long do I Have?”  Ashleigh Long, Richard Kryscio, Gregory Jicha

P3.198

Frontal Release Signs in Adults with Down Syndrome Are Associated with Dementia  Gregory Jicha, Mellani Lefta, William Robertson, Elizabeth Head, Frederick Schmitt

P3.199

Computerized Cognitive Testing of Individuals with Down Syndrome and Alzheimer Disease  Michael Gutman, Ethan Moskovic, Joseph Jeret

Poster Session III

P3.200

Clinical Features of Mild Cognitive Impairment of the Cerebrovascular Type (MCI-CVD) Gregory Jicha, Laura Hench, Debra Moser, Erin Abner

P3.201

Clinical Characteristics of bvFTD Across CDR Stages Kamalini Ranasinghe, Peter Pressman, David Perry, Katherine Rankin, Bruce Miller

P3.202

Visual Perception Test Predicts a Pathological Diagnosis of Alzheimer’s Disease in Patients Presenting with Corticobasal Syndrome  Clara Boyd, Michael Tierney, Eric Wassermann, Karen Marder, Salvatore Spina, Adrian Oblak, Bernardino Ghetti, Jordan Grafman, Edward Huey

P3.203

Mental Status Examination Practices Among Resident and Attending Physicians in Patients Hospitalized for Evaluation of Confusion  Serggio Lanata, Brian Ott

P3.204

Assessment of Memory in the Clinic: How Useful Is Cued Recall? Christian Bocti, Catherine Liu, Helene Imbeault, Nancy Leblanc, Francis Langlois

P3.205

Plasma Levels of HDL and Carotenoids Are Lower in Alzheimer’s Disease Patients with Vascular Comorbidities But Plasma Protein Nitration and Oxidation Is Unaffected Gereon Nelles, Irundika Dias, Daniela Weber, Li Li, Wilhelm Stahl, Tilman Grune, Maria Polidori, Helen Griffiths

P3.206

Atypical Antipsychotic Utilization in Dementia Patients at a Long-Term Care Facility: A Retrospective Study  Douglas Scharre, Shu-Ing Chang, Haikady Nagaraja, Michael Merjanian, Gail Greenley, Rebecca Davis

P3.207

P3.212

The Role of Gender Differences in Dementia Caregiver Risk  Carol Lippa, Kate Bowen, Candace Robertson-James, Ana Nunez, Elizabeth Gonzalez

P3.213

Normal Cognition in a 99-yearold Man with High Levels of Alzheimer Disease Pathology  Kristoffer Nissinen, Barbara Agee Shah, Maria Corrada, Ronald Kim, Szofia Bullain, Claudia Kawas

P3.214

Intermittent Temporal Slowing in Cognitively Normal Oldest-old: The 90+ EEG Study  Szofia Bullain, Maria Corrada, Dana Greenia, Claudia Kawas

P3.215

Neuropsychiatric Symptoms, ApoE4 and the Risk of Incident Dementia: The Mayo Clinic Study of Aging  Anna Pink, Jazmin Acosta, Rosebud Roberts, Michelle Mielke, Teresa Christianson, Vernon Pankratz, G Stokin, Bradley Boeve, Yonas Geda

P3.216

Cognitive Reserve markers independently predict Cognitive outcomes in patients with SAH  Neha Dangayach, Laura Zhaodne, Yaakov Stern, Christina Falo, Sachin Agarwal, Meyers Emma, Jan Claassen, Stephan Mayer

Aging, Dementia, and Cognitive and Behavioral Neurology: Executive Function P3.217

Functional Near-Infrared Spectroscopy (fNIR) based Detection of Increased Prefrontal Cortex Activity in Frontotemporal Dementia  Jillian Edwards, Tooba Fayyaz, Lauren Scull, Hasan Ayaz, Patricia Shewokis, David Libon, Carol Lippa, Anahita Deboo, Terry Heiman-Patterson

Amyloid PET Screening for Enrollment into Alzheimer’s Disease Clinical Trials: Initial Experience in a Phase 1b Clinical Trial  Jeff Sevigny, Joyce Suhy, Ping Chiao, Gregory Klein, Joonmi Oh, Derk Purcell, Mehul Sampat, Jerome Barakos

P3.218

P3.208

Cognitive and Functional Decline and their Relationship in Patients with Mild Alzheimer’s Disease  Hong LiuSiefert, Eric Siemers, Karen Sundell, Karen Price, Baoguang Han, Katherine Selzler, Joel Raskin, Richard Mohs

P3.219

P3.209

P3.220

Florbetapir F18 PET Amyloid Neuroimaging and Baseline Characteristics in Patients with Alzheimer’s Dementia Elisabeth Degenhardt, Michael Witte, Michael Case, Peng Yu, David Henley, Helen Hochstetler, Deborah DSouza, Paula Trzepacz

P3.210

Impact of Amyloid Beta Imaging on Diagnosis and Clinical Management of Hypothetical Patients with Mild Cognitive Impairment or Dementia.  Joshua Cohen, Yue Zhong, Jason Karlawish

P3.211

MRI Volumetric Analysis, Cognitive Profiles and Biomarkers in a Sample of Argentina -ADNI patients  Marcos Fernandez Suarez, Griselda Russo, Patricio Chrem Mendez, Fernando Ventrice, Ezequiel Surace, Maria Russo, Jorge Campos, Federico Nahas, Gustavo Sevlever, Silvia Vazquez, Ricardo Allegri

Strategic Choice In Frontotemporal Dementia: Evidence From The Ultimatum Game  Stefano Cappa, Alessandra Dodich, Chiara Cerami, Nicola Canessa, Chiara Crespi, Alessandra Marcone Digit Span: A Comparison of Chinese Versus Alphabetic Language Speakers in Dysexecutive Dementia Patients  Simon Kang Seng Ting, Shahul Hameed, Eng-King Tan, Christopher Gabriel, Kinjal Doshi

P3.224

Neuroanatomy of GoalDirected Behavior in behavioral variant Frontotemporal Degeneration Lauren Massimo, John Powers, Lois Evans, Brianna Morgan, Corey McMillan, Katya Rascovsky, Paul Eslinger, Mary Ersek, Murray Grossman

P3.225

Temporal Discounting of Future Rewards in Behavioral Variant Frontotemporal Dementia (bvFTD) and Alzheimer’s Disease (AD)  Katya Rascovsky, Joe Kable, Rebecca Kazinka, Eileen Moran, Christopher Olm, Jenna Glasenberg, Ashley Boller, Joe McGuire, Corey McMillan, Robin Clark, Murray Grossman

P3.226

Video Tracking of Cancellation Is Sensitive to Acute Brain Impairment and Disability  Lynita Mullins, Victor Mark, Adam Woods, Mary Banasiewicz

Epilepsy and Clinical Neurophysiology: Clinical Manifestations P3.227

Epileptic Vertigo and Dizziness—a Systematic Review of the Literature  Alexander Tarnutzer, Seung-Han Lee, Karen Robinson, Peter Kaplan, David Newman-Toker

P3.228

Whistling Seizure: A Unique Case Report of a Rare Automatism Kaitlyn Lillemoe, Daniel Torres, Anuradha Singh

P3.229

Post-ictal Lateralized Hyperkinetic Motor Behavior  Brian Beck, Gregory Chang

P3.230

Epilepsy Classification in Adults with a First Epileptic Seizure; Experience from a Tertiary Epilepsy Clinic  Michael Koutroumanidis, Vasiliki Tsirka, Ioannis Zoukos, Mark Richardson

P3.231

Seizures Without Awareness: A Pure Cohort  William Tatum, Langston Michael, Kirsten Yelvington, Jerry Shih

P3.232

A Stimulating Inner Conversation  Daniel Goldenholz, Xiangping Zhou, William Theodore, Kareem Zaghloul, Sara Inati

P3.233

Pancytopenia Associated with Shapiro Syndrome in a Patient with Posterior Porencephaly  Jordan Schaefer, Amy Crepeau, Vilmarie Rodriguez

Transfer of Working Memory Performance Enhancement Induced by Transcranial Direct Current Stimulation (tDCS)  Jay Gill, Roy Hamilton

P3.234

P3.221

P3.235

Correlation of Executive Dysfunction and Delusions or Hallucinations with Autoimmune and Paraneoplastic Antibodies in Elderly Presenting with Memory Complaints  Rhonna Shatz, Wendy Lemere, Lynn Etters, Marina Novikova

P3.222

Hyperostosis Frontalis Interna, Causing Frontal Lobe Dysfunction and Refractory Headaches  Mitra Assadi Khansare, Marc Duome, Arlan Mintz

P3.223

Beyond Words: Pragmatic Inference in the Behavioral Variant of Frontotemporal Dementia  Nicola Spotorno, Corey McMillan, Katya Raskovsky, Robin Clark, Murray Grossman



Hemimegalencephaly: Adult Evolution  Nicky Wu, Felippe Borlot, Anfal Ali, Timo Krings, Andres Lozano, Danielle Andrade New Onset Seizures in Elderly: Clinical Presentation and Etiology of First Ever Seizure  Erum Shariff, Majed Alhameed

P3.236

Subclinical EEG Seizures as a Predictor of Tumor Progression in Brain Tumor Patients Presenting with Altered Mental Status  Meghan Ward, Simran Singh, Irena Garic, Jeffrey Kennedy, Priya Kumthekar, Michael Macken, Elizabeth Gerard, Jeffrey Raizer, Stephan Schuele

Epilepsy and Clinical Neurophysiology: AED P3.237

Safety of Eslicarbazepine Acetate in Patients with Refractory PartialOnset Seizures Treated With or Without Concomitant Carbamazepine: A Pooled Analysis of Three Phase III Controlled Studies  Selim Benbadis, Victor Biton, Mercedes Jacobson, Eugen Trinka, Mar Carreño, David Blum, Patrício Soaresda-Silva, Helena Gama, Rui Sousa, Todd Grinnell, Raymond Claus

P3.238

Effects of Eslicarbazepine Acetate on Cardiac Function in Patients with Refractory Partial-Onset Seizures: A Pooled Analysis of Three Phase III Controlled Studies  Inna Vaisleib, Patricia Penovich, Bassel Shneker, Elza Yacubian, David Blum, Helena Gama, Patrício Soaresda-Silva, Todd Grinnell

P3.239

Efficacy of Eslicarbazepine Acetate in Patients with Refractory Partial-Onset Seizures Treated With or Without Concomitant Carbamazepine: A Pooled Analysis of Three Phase III Controlled Studies  Steve Chung, Gregory Krauss, Michael Sperling, Eugen Trinka, Mar Carreño, David Blum, Patrício Soares-daSilva, Rui Sousa, Todd Grinnell, Hailong Cheng

P3.240

Safety of Eslicarbazepine Acetate in Elderly Subjects: A Pooled Analysis of Five Phase II Placebo-controlled Non-Epilepsy Studies  Eva Andermann, R. Eugene Ramsay, Elinor Ben-Menachem, David Blum, Helena Gama, Patrício Soaresda-Silva, Todd Grinnell

P3.241

Incidence of Allergic Reaction Adverse Events during Adjunctive Treatment with Eslicarbazepine Acetate in Patients with Refractory Partial-Onset Seizures: A Pooled Analysis of Three Phase III Placebo-Controlled Studies Joanne Rogin, Trevor Resnick, Laura Strom, Elinor Ben-Menachem, Silvia Kochen, David Blum, Helena Gama, Patrício Soares-da-Silva, Todd Grinnell

P3.242

Conversion to Monotherapy with Eslicarbazepine Acetate in Adults with Partial-Onset Seizures—Results of a North-American Study  Michael Sperling, J. Harvey, David Blum, Todd Grinnell

P3.243

Co-administration of Carbamazepine with Eslicarbazepine Acetate Decreases Eslicarbazepine Exposure: A Population Pharmacokinetic Analysis  Blanca Vazquez, Robert Wechsler, William Rosenfeld, Christian Elger, Pedro Kowacs, Patrício Soares-da-Silva, Joana Moreira, Jahnavi Kharidia, Gary Maier, David Blum, Todd Grinnell

P3.244

Pharmacokinetic Rationale for mg-to-mg Overnight Switch from b.i.d. Immediate Release Topiramate (TPM-IR) to Extended-release Once-daily SPN-538 (Trokendi XR™)  Jennifer Dugan Stocks, Janet Johnson, Scott Brittain, Paolo Baroldi

Fast, Easy Registration Online  ·  AAN.com/view/AM14

75

Tuesday April 29



First Authors stand by Posters from 5:00 p.m.–6:30 p.m.



Tuesday, April 29 P3.245

Steady-State Bioequivalence of Extended-release Once-daily SPN-538 (Trokendi XR™) to Immediate-Release Topiramate (TPM-IR, Topamax®) Janet Johnson, Scott Brittain, Jennifer Dugan Stocks, Paolo Baroldi

P3.246

Topiramate Pharmacokinetics of Extended-release Once-daily SPN-538 (Trokendi XR™) in the Elderly Welton O’Neal, Scott Brittain, Jennifer Dugan Stocks, Janet Johnson, Paolo Baroldi

P3.247 Pharmacokinetic-

Pharmacodynamic Analysis of Extendedrelease Once-daily Oxcarbazepine Formulation SPN-804 (Oxtellar XR™) in Adults with Epilepsy  Scott Brittain, Janet Johnson, Paolo Baroldi

P3.248 Oxcarbazepine

Pharmacokinetics of Extended-release Once-daily SPN-804 (Oxtellar XR™) in the Elderly  Welton O’Neal, Scott Brittain, Janet Johnson

P3.249

Long-Term Efficacy of Clobazam for Drop Attacks in LennoxGastaut Syndrome Is Consistent Across Patient Age Ranges  Jouko Isojarvi, Deborah Lee, Vivienne Shen, Jeffrey Buchhalter

P3.250

Patients Treated with Clobazam Experienced Fewer Seizurerelated Injuries Than Placebo Patients During the Phase III CONTAIN Trial in Lennox-Gastaut Syndrome  Jouko Isojarvi, Michael Sperling, Deborah Lee

P3.251

IV Carbamazepine (CBZ) as Short-Term Replacement Therapy for Oral CBZ in Adults with Epilepsy: Primary Results of a Phase III Safety Trial Suresh Dheerendra, Pavel Klein, Victor Biton, Xiaolin Zhang, Uwa Kalu, Deborah Lee, Jonathan Halford

P3.252

Clobazam Response in Patients with Previous Benzodiazepine Use: Subanalysis of the Phase III CONTAIN Trial in Lennox-Gastaut Syndrome (LGS)  Deborah Lee, William Rosenfeld, Jouko Isojarvi

P3.253

Long-Term Response to Clobazam By Baseline Seizure Frequency in Patients with Lennox-Gastaut Syndrome (LGS)  Deborah Lee, James Wheless, Jouko Isojarvi

P3.254

Efficacy and Safety of Clobazam in Lennox-Gastaut Syndrome: Completers Analysis of the 15-week, Phase III CONTAIN Trial  Joan Conry, Yu-Tze Ng, Guangbin Peng, Deborah Lee, Jouko Isojarvi

P3.255

A Comparison Between Pharmacological Treatment of Epileptic Patients with and Without Intellectual Disability.  Jonathan Fridhandler, Fernando Coelho, Peter Tai, Nathalie Jette, Danielle Andrade

P3.256

How Well Do We Know Our AEDs? Neurology Resident Screening Practices of AED Side Effects Gunjan Narwani, Reena Nanjireddy, Aashit Shah, Maysaa Basha

76

P3.257

Impact of Delayed-Dose Administration of USL255, an Extendedrelease Topiramate Formulation Bob Anders, Qiang Lu, Elizabeth Ludwig, Annie Clark

P3.258

Comparison of the Pharmacokinetics of USL255, an Extendedrelease Topiramate, When Sprinkled onto Soft Food or Swallowed Intact  Annie Clark, Bob Anders, Mark Halvorsen

P3.259

Extended-release Oncedaily SPN-538 (Trokendi XR™) Versus Twice-Daily TPM-IR (Topamax®): Impact of Dosing Irregularities on Topiramate Concentrations  Scott Brittain

P3.260

Dose Linearity and Dose Strength Equivalence of Extendedrelease Once-daily SPN-538 (Trokendi XR™)  Jennifer Dugan Stocks, Erika Roers, Scott Brittain, Paolo Baroldi

P3.261

Efficacy, Safety, and Impact on Quality of Life of USL255 in Patients with Refractory Partial-Onset Seizures: The PREVAIL Study  Steve Chung, Toufic Fakhoury, Stephan Arnold, Balduin Lawson, Ilan Blatt, Annie Clark, Mark Halvorsen, Venkatesh Nagaraddi, Bob Anders

P3.262

Adverse Event Profile of USL255 in Patients with Refractory PartialOnset Seizures: The PREVAIL Study Robert Hogan, Stephan Arnold, Toufic Fakhoury, Bob Anders

P3.263

Efficacy of USL255 Across Partial-Onset Seizure Types and Refractory Patient Status: Subgroup Analyses From the PREVAIL Study  Ilan Blatt, Venkatesh Nagaraddi, Robert Hogan, Stephan Arnold, Balduin Lawson, Bob Anders, Annie Clark, Mark Halvorsen, Steve Chung

P3.264

Early Onset of Efficacy and Safety Outcomes with USL255 Treatment: The PREVAIL Study  Venkatesh Nagaraddi, Steve Chung, Stephan Arnold, Annie Clark, Bob Anders, Toufic Fakhoury

P3.265

USL255, Extended-release Topiramate, Displays an Improved Pharmacokinetic Profile with Reduced Adverse Events Compared with ImmediateRelease Topiramate  Annie Clark, Robert Hogan, Bob Anders

P3.266

Comparison of Adverse Effects of USL255 and Commonly Prescribed AEDs: Assessment of Relative Risk  Kimford Meador, Frank Gilliam, Robert Hogan, Mary Holmay, Annie Clark, Bob Anders

P3.267

Therapeutic Time Window of Perampanel for the Termination of Diazepam-Resistant Status Epilepticus (SE) in a Lithium-Pilocarpine Rat Model  Katsutoshi Ido, Takahisa Hanada

P3.268

Perampanel Clinical Studies: Analysis of Psychiatric and Behavioral Events  Alan Ettinger, Antonia LoPresti, Haichen Yang, Betsy Williams, Sharon Zhou, Randi Fain, Antonio Laurenza

3:00 p.m.–6:30 p.m. P3.269

Effect of Adjunctive Lacosamide on Complex Partial Seizures and Partial Seizures with Secondary Generalization in Adults: Pooled Analysis of Three Open-label Extension Trials Svetlana Dimova, Cindy McShea, Pamela Doty, Konrad Werhahn, Marc De Backer

P3.270

Anti-Seizure Effects of Perampanel in Combination with Other Antiepileptic Drugs (AEDs) in a Rat Amygdala Kindling Model  Ting Wu, Takahisa Hanada

P3.271

Interim Efficacy and Safety Analysis of Adjunctive Perampanel in the Adolescent Population from the Extension Phase of 3 Double-Blind, Placebo-Controlled, Phase 3 (Core) Studies in Patients with Refractory Partial-Onset Seizures  Ben Renfroe, Haichen Yang, Betsy Williams, Steven Huang, Antonio Laurenza

P3.272

Analysis of Falls in Epilepsy Patients with Partial Onset Seizures in Perampanel Phase 3 Trials  Ilo Leppik, Haichen Yang, Betsy Williams, Sharon Zhou, Randi Fain, Antonio Laurenza

P3.273

Efficacy and Safety of Adjunctive Perampanel Based on Number of Antiepileptic Drugs at Baseline Tracy Glauser, Antonio Laurenza, Haichen Yang, Betsy Williams, Dongyuan Xing, Randi Fain

P3.274

Lacosamide Conversion to Monotherapy for the Treatment of Partialonset Seizures in Adults: Results from a Multicenter, Randomized, Double-blind, Historical-controlled Trial  Robert Wechsler, George Li, Jacqueline French, Terence O’Brien, O Neil D’Cruz, Paulette Williams, Melissa Brock

P3.275

Lacosamide Added to Existing Monotherapy in Epilepsy Patients with Partial Onset Seizures: Second Interim Analysis of the VITOBA Study Matthias Noack-Rink, Thomas Mayer, Stephan Arnold, Uwe Runge

P3.281

Differences in Usage of Clobazam Versus Clonazepam for Epilepsy  Daniel Jones, Jouko Isojarvi, Alice Guiraud-Diawara, Vivienne Shen, Patrice Verpillat

P3.282

What a “Drop-Out” Reveals About the Nocebo Effect in Patients Tricia Ting, James Polli, Wenlei Jiang

P3.283

Hematologic Profile Associated with Newer-generation Anti-epileptic Medications in the Pediatric Population  Puja Joshi, Sonam Verma, Anita Sui, Yen-Hong Kuo, Victor Johnson, Richard Sultan

P3.284

Long-term Open-label Extension (OLE) Study Evaluating USL255, Once-daily Extended-release Topiramate, in Patients with Partial Onset Seizures: Interim Analysis from PREVAIL OLE Toufic Fakhoury, Robert Hogan, Ilan Blatt, Steve Chung, Bob Anders

P3.285

Pharmacokinetics of USL261, a Novel Intranasal Formulation of Midazolam, in Subjects with Epilepsy Lindy Bancke, Heather Dworak, Mark Halvorsen

P3.286

Lacosamide Experience in Patients with Lennox-Gastaut Syndrome and Epilepsy  Pedro Bermejo, Andres Cruz

P3.287

Cortical Mapping of Language in the Basal Temporal Area in Pediatric Patients Undergoing Epilepsy Surgery Evaluation.  Christelle Moufawad El Achkar, Joseph Madsen, Jeffrey Bolton, Tobias Loddenkemper

Myopathies/Muscle Disease P3.288

Abnormalities of Mitophagy in Sporadic Inclusion-Body Myositis (s-IBM) Muscle Fibers  Anna Nogalska, Carla D’Agostino, Mafalda Cacciottolo, King W. Engel, Valerie Askanas

P3.289

P3.276

Lacosamide for Uncontrolled Primary Generalized Tonic-clonic Seizures: An Open-label Extension Study Stephen Yates, Robert Wechsler, Cynthia Beller

Progressive Ophthalmoplegia with Ocular and Generalized Myopathy with Ragged-Red Fibers, Linear Scleroderma and Contralateral Cerebral Hemiatrophy  Walter Haupt, Monika Rabenstein, Anna Brunn, Lothar Burghaus

P3.277

Safety and Pharmacodynamics of USL261, a Novel Intranasal Formulation of Midazolam, in Subjects with Epilepsy  Robert Hayes, Lindy Bancke, Heather Dworak

P3.290

P3.278

P3.291

Can We Trust Standard Healthy Volunteer Data to Assess Generic Drug Quality: Lamotrigine Experience in Patients?  James Polli, Tricia Ting, Wenlei Jiang

P3.279

Levetiracetam in the Treatment of Epilepsy as Add On or Mono Therapy  Sarwer Al-Bajalan, Murad Kamel

P3.280

Use of Investigator Training to Improve Seizure Classification in PREVAIL: A Phase 3, Global Study Evaluating USL255, Once-daily Extended-release Topiramate, in Adults with Partial-Onset Seizures  Bree DiVentura, Jacqueline French, Bob Anders, Dawn Laine

2O14 Scientific Abstract Listing and Annual Meeting Information

Carnitine Deficiency, A Spectrum Disorder: Case Series and Histopathological and Ultrastructural Characterization  Amanda Michael, Bassam Malo, Stanley Iyadurai Early Onset and Fulminant Course of Sporadic Inclusion Body Myositis (sIBM): A Case Report  Alison Walsh, Goran Rakocevic

P3.292

Lipid Storage Myopathy Unmasked by the Antianginal Drug Ranolazine  Charles Kassardjian, Duygu Selcen, Georgirene Vladutiu, Lee-jun Wong, Margherita Milone

P3.293

Late-onset Pompe Disease: A Case Series.  Omar Jawdat, Mamatha Pasnoor, April McVey, Ahmad Abuzinadah, Laura Herbelin, Richard Barohn, Mazen Dimachkie, Majed Dasouki

P3.294

Not PFK Deficiency Lydia Sharp, Nadine Romain, Ronald Haller

Poster Session III

P3.295

Clinical Anatomical and Epidemiologic Study of 11 Patients with McArdle’s Disease  Alzira Carvalho, Pâmela Delgado, Miriam Koch, David Feder

P3.296

Asymptomatic Pompe Disease: A Study of 6 Patients. Andoni Echaniz-Laguna, Robert-Yves Carlier, Kenza Laloui, Pierre Carlier, Emmanuelle SalortCampana, Jean Pouget, Pascal Laforet

Neurologic Complications of Cancer P3.307

Myelitis Following Intrathecal Chemotherapy in Acute Lymphoblastic Leukemia: A Case Report  Alicia Parker, Ahmed Yassin, Karin Woodman

P3.308

Muscle Disease

Atypical Neurological Complications of Ipilimumab Therapy in Patients with Metastatic Melanoma Alicia Parker, Ahmed Yassin, Karin Woodman

P3.297

P3.309

Pompe Disease: Distal Myopathy in a Previously Unreported Heterozygous Variant  João Dib, Osvaldo Nascimento, Eduardo Davidovich, Ricardo Dornas, Camila Pupe, Bruno Coutinho

P3.298

Frequencies of Seven Muscle Enzyme Deficiencies in Samples Tested for Myoglobinuria in a Clinical Laboratory  Malgorzata Jaremko, Kaylan Burnham, Maximo Tatis, Jamie Willis, Sat Dev Batish, Joseph Higgins

P3.299

A Diagnostic Flowchart for POLG Related Diseases Based on Signs Sensitivity and Specificity Maya Tchikviladzé, Mylène Gilleron, Thierry Maisonobe, Damien Galanaud, Pascal Laforet, Alexandra Durr, Bruno Eymard, Fanny Mochel, Hélène Ogier, Anthony Béhin, Tanya Stojkovic, Bertrand Degos, Isabelle Gourfinkel-An, Frederic Sedel, Mathieu Anheim, Alexis Elbaz, Karine Viala, Marie Vidailhet, Alexis Brice, Claude Jardel, Anne Lombes

P3.300 Myopathy as a Cause of

Camptocormia: A Prospective Study JeanBaptiste Chanson, Béatrice Lannes, Andoni Echaniz-Laguna

P3.301

Serum Cytokine Analysis in Idiopathic Inflammatory Myopathies Diagnosed on the Basis of Pathological Findings  Meiko Maeda

P3.302

Expanding the Clinical and Genetic Spectrum of MYH7 Related Skeletal Myopathies in the United Kingdom  Kathryn Brennan, Anna Sarkozy, Cheryl Longman, Michela Guglieri, Tuomo Polvikoski, Maria Farrugia, Richard Petty, Victoria Murday, Dean John, Steven Hardy, Hanns Lochmuller, Katie Bushby, Volker Straub

P3.303

Paroxysmal Vocal Cord Motion Dysfunction Masquerading as Neuromuscular Disorders  Darine Kassar, William Arnold, Chad Hoyle, John Kissel

A Unique Presentation of Pediatric Stroke Attributed to Intrathecal Methotrexate  Mohammed Ilyas, Mitchel Williams

P3.310

Nafcillin® and Rifampin® Therapy for MSSA Ventriculitis Associated with CSF Shunt: A Case Report Christopher Goshgarian, Abdulrahman Alwaki, Anibal Lugo, Tamer Abdelhak

P3.311

Corneal Confocal Microscopy in Patients with Chemotherapy-Induced Neuropathy  Marta Campagnolo, Daniela Lazzarini, Iva Fregona, Mario Cacciavillani, Francesca Bergamo, Raffaele Parrozzani, Edoardo Midena, Chiara Briani

P3.312

Characterization of Seizures and Their Response to Treatment in a Cohort of Patients with Glial Tumors in a University Institute  José Tafur Canabal, Alejandra Gonzalez Roffo, Valeria Beatriz Kuchkaryan, Victoria Campanucci, Jorge Igirio Gamero, Alejandra Báez, Cecilia Sánchez Retamar, Ignacio Casas Parera

P3.313

Epilepsy and Cancer: Ancient Problem in a Top Mortality Illness Bernardo Cacho Diaz

P3.314

Palinopsia and Palinacousis  Emily Johnson, Mohammad Salajegheh

P3.315

Focal Injection of Incobotulinum Toxin A Improves Refractory Local Cancer Pain at the Site of Radiation/ Surgery  Rezvan Rostami, Duarte Machado, Diana Richardson, Bahman Jabbari

P3.316

Neuropathic Itch as a Presenting Feature of Post-Mastectomy Pain Syndrome  Robert Knobler

Neuro-oncology: Paraneoplastic Syndromes and Other Antibodymediated Disorders P3.317

P3.304

Myalgia and Hyper-CKemia Due to Novel Homozygous ANO5 Deletion  Rajat Lahoria, Thomas Winder, Jie Liu, Margherita Milone

Humoral Immune Response Against Neural Antigens in Endometrial Cancer Patients  Slawomir Michalak, Karolina Poplawska-Domaszewicz, Agata Paluch, Dariusz Szpurek, Stefan Sajdak, Wojciech Kozubski

P3.305

P3.318

Slow Channel Syndrome Leading to Distal Myopathy in a Large Family: Therapeutic Perspectives Corrado Angelini, Giovanni Vazza, Maria Mostacciuolo

P3.306

Familial Distal Myopathy Due to PNLPA2 Mutation  Corrado Angelini, Daniela Tavian, Elisabetta Tasca, Sara Missaglia

The Expression of Neurotrophic Factors in Peripheral Blood Mononuclear Cells and Neurological Complications of Cancer Slawomir Michalak, Joanna Rybacka-Mossakowska, Daria Swiniuch, Joanna Gazdulska, Maria Litwiniuk, Rodryg Ramlau, Wojciech Kozubski

P3.320 Anti-NMDA-receptor

Encephalitis: Case Report of Persistent Anti-NMDAR Antibodies 10 Years from Initial Undiagnosed Presentation Maria Fang-Chun Chen, Michelle Dougherty, Josep Dalmau

P3.321

Atypical Encephalitis with Voltage-gated Potassium Channel (VGKC) and N-Methyl-D-Aspartate-Receptor (NMDAR) Antibodies with HIV and Pathologic Confirmation  Debra Ehrlich, Atul Ramesh, Steven Herskovitz, Howard Geyer, Patrick Lasala, Karen Weidenheim, Jerome Graber

P3.322

Suspected Paraneoplastic Autonomic Neuropathy in a Patient with Newly Diagnosed Glioblastoma Multiforme  Alyx Porter, Brent Goodman

P3.323

The Population-based Survey of Paraneoplastic Neurological Syndromes in the Czech Republic During the Eight Years´ Period  Pavel Stourac, Jana Bednarova, Petra Praksova, Magdalena Hladikova, Krystyna Kantorova

Child Neurology and Developmental Neurology III P3.332

Behavioral Profiles of Children and Adolescents with Specific Language Impairment and High Functioning Autism  Marisela Dy, Angela Ballantyne, Doris Trauner

P3.333

Acute Disseminated Encephalomyelitis in a Pediatric RenalTransplant Recipient.  Daniel Vela-Duarte, Eugene Schnitzler, Vikram Prabhu

P3.334

An Unusual Prolonged Presentation of Synthetic Cathinone Encephalopathy Responsive to Steroids: A Case Report  Rawan Albadareen, Jennifer Lowry, Stephen Thornton, Arezou Heshmati

P3.335

A Polio-Like Syndrome in California: Clinical, Radiologic, and Serologic Evaluation of Five Children Identified by a Statewide Laboratory Over a Twelve-Month Period  Alexandra Roux, Sabeen Lulu, Emmanuelle Waubant, Carol Glaser, Keith Van Haren

P3.324

P3.336

Neuro-oncology: Meningioma, Neurofibromatosis, and Other Non-glial Tumors

P3.337

Glioblastoma Multiforme in a Patient with Multiple Sclerosis: A Case Report  Carlos Romo, Aline Herlopian, Nabeel Chauhan, Robert Archer, Shirley Ong

P3.325

Hormone Replacement Therapy Increases the Risk of Cranial Meningioma  Lene Andersen, Soren Friis, Jesper Hallas, Pernille Ravn, Henrik Daa Schrøder, David Gaist

P3.326

Clinical and Radiological Response of NF2 Associated Tumours to Bevacizumab in an English Cohort Katrina Morris, Shazia Afridi, Patrick Axon, Gareth Evans, Allyson Parry, Dorothy Halliday, Pieter Pretorius

P3.327

Neurofibromatosis 2 with Limited Phenotype in a Kindred with Deletion of Exon 9 in the NF2 Gene. Leif Wiklund, Anna Flodin, Karin Zyk-Zackrisson, Ole Kvorning, Margareta Nordling

P3.328

Novel Constitutional Chromosomal Deletion, 4q32.1, in a Patient with Neurofibromatosis Type 1 and Glioblastoma Multiforme Amanda Michael, Colin Hirst, Ryan Miller, Miguel Guzman, Ghazala Hayat

P3.329

Diagnostic Dilemma of Bell’s Palsy: Case of Facial Nerve Schwannoma Presenting as Acute Bell’s Palsy Nidhi Mehta, Satinder Kaur, Kelsey West

Abnormalities of the Brain Functional Connectome in Pediatric Patients with Multiple Sclerosis Massimo Filippi, Paola Valsasina, Sara Sala, Vittorio Martinelli, Angelo Ghezzi, Pierangelo Veggiotti, Andrea Falini, Giancarlo Comi, Maria Rocca Ten Years in the Making—A Longitudinal Study of Language Development in Children and Adolescents  Jerzy Szaflarski, Yingying Wang, Mekibib Altaye, Akila Rajagopal, Anna Byars, Elena Plante, Scott Holland

P3.338 Magnetoencephalographic

Parameters of Fetal Brain Maturation  Naim Haddad, Hari Eswaran, Eric Siegel, Curtis Lowery, Rathinasami Govindan, Srinivasan Vairavan

Neuroscience Research Prize Recipients P3.339

Evidence of Toll-like Receptor Nine-mediated Amelioration of Amyloid Pathology in a TgSwDI Mouse Model of Alzheimer’s Disease  Charlotte Herber

P3.340

Promoting Repair of Damaged Corticospinal Tract  Stefanie Henry

P3.341 Pan-neuronal

Over-expression of the GCLc Gene to Mitigate Redox Stress and Mitochondrial ETC Complex Dysfunction in Alzheimer’s Disease  Lisa Michaels

P3.330

Treatment of Pituitary Tumors with Temozolomide: A Case Series Justin Jordan, Tucker Cushing, Jorg Dietrich

P3.331

Thoracolumbar Spinal Angiolipoma Demonstrating High Signal on STIR Imaging: A Case Report.  Alex Linn, Denny Reyes

P3.319

Atypical Neuroimaging Findings in Hodgkin’s Lymphoma Associated with Anti-GAD Antibodies  Caelan Ford, Ratna BhavarajuSanka, Rebecca Romero



Fast, Easy Registration Online  ·  AAN.com/view/AM14

77

Tuesday April 29



First Authors stand by Posters from 5:00 p.m.–6:30 p.m.



Tuesday, April 29 S14 MS and CNS Inflammatory Disease: Animal and In Vitro Studies 3:15 p.m. S14.001 Endothelial TREK1 Potassium Channels Are Critical Regulators of Immune Cell Migration into the CNS   Stefan Bittner, Tobias Ruck, Kerstin Goebel, Nico Melzer, Heinz Wiendl, Sven Meuth 3:30 p.m. S14.002 Amyloid Fibril-forming Hexapeptides Modulate the Immune Response and Reduce Symptoms in an Animal Model of Multiple Sclerosis   Michael Kurnellas, Jonathan Rothbard, Jill Schartner, Lawrence Steinman 3:45 p.m. S14.003 Contribution of a Dysfunctional RNA Binding Protein, hnRNP A1, to Neurodegeneration in MS   Michael Levin, Sangmin Lee, Lidia Gardner, Joshua Douglas, Yoojin Shin, Paul Sawchenko, Stephen Lalor, Benjamin Segal 4:00 p.m. S14.004 A Nasal Anti-CD3 Vaccine Treats a Model of Secondary Progressive MS by Inducing IL-10 Dependent T Regulatory Cells and Regulating CNS Innate Immunity   Lior Mayo, Andre Pires Da Cunha, Raymond Sobel, Hans Lassmann, Francisco Quintana, Howard Weiner 4:15 p.m. S14.005 IRX4204: A Highly Selective RXR Agonist Modulates Adaptive Treg Differentiation Independent of RAR, and Effectively Inhibits Central Nervous System Inflammation   Elizabeth Nowak, Rosh Chandraratna, Randolph Noelle 4:30 p.m. S14.006 IRX4204: A Clinical Stage, Potent, and Highly Selective RXR Agonist Compound Is Brain Penetrant, and Promotes Differentiation of Oligodendrocyte Precursor Cells (OPCs) In Vitro   Martin Sanders, Satish Medicetty, Rosh Chandraratna 4:45 p.m. S14.007 Effects of Polarized Human Lymphocytes and Myeloid Cells on Astrocyte Responses and Oligodendrocyte Differentiation   Craig Moore, Nebras Warsi, Qiao Ling Cui, Bryce Durafourt, Jack Antel, Amit Bar-Or

78

S15 Cerebrovascular Disease and Interventional Neurology: Clinical and Imaging Biomarkers and Genetics 3:15 p.m. S15.001 Abnormal Left Ventricular Geometry in Lacunar Stroke: Spectrum, Prevalence and Prognostic Implications in the SPS3 Trial   Thalia Field, Lesly Pearce, Nathan ChanSmyth, Sabe De, Gordon Gubitz, Stephen Phillips, Robert Hart, Oscar Benavente 3:30 p.m. S15.002 Infarction Volume in Patients with Atrial Fibrillation: The Impact of Left Ventricular Stiffness   Hee-Seung Ahn, Wi-Sun Ryu 3:45 p.m. S15.003 The Collateral Circulation on Day-2 CT Angiography Is a Reliable Predictor of Functional Outcomes in Acute Ischemic Stroke.   Leonard Yeo, Prakash Paliwal, Hock Luen Teoh, Bernard Chan, Chee Seong Seet, Eric Ting, Gavin Lim, Venetia Ong, Ganesh Shamugam, Amit Varma, Vijay Sharma 4:00 p.m. S15.004 Identifying Novel Biomarkers of Cerebral Ischemia through the Use of Mass Spectroscopy   Paul George, Christopher Adams, Michael Mlynash, Christian Kjaergaard, Calvin Kuo, Stephanie Kemp, Madelleine Garcia, Gregory Albers, Jean-Marc Olivot 4:15 p.m. S15.005 Proteomic Profiling of Acute Stroke Patients Post IV Thrombolysis: Mapping tPA Efficacy in Real Time   MingMing Ning, Mary Lopez, David Sarracino, David McMullin, Xiaoying Wang, Ferdinando Buonanno, Eng Lo 4:30 p.m. S15.006 COL4A1 Mutations: Clinical and Radiological Phenotypes in a French Adult Cohort   Aurélie Siri, Elisabeth Tournier-Lasserve, Manuelle Mine, Eloi Magnin, Eric Berger, Caroline Arquizan, Xavier Ayrignac, Clarisse Carra-Dalliere, Giovanni Castelnovo, Nicolas De Champfleur, Pierre Labauge, Jean Philippe Neau, Tiphaine Rouaud, Sonia Alamowitch 4:45 p.m. S15.007 An Autosomal Dominant Arteriopathy of the Brain Due to a Novel Mutation in Collagen 4A1 Gene in a Family with Early-onset Stroke and Leukoencephalopathy   Matthew Schrag, William Graf, Anna Szekely

3:15 p.m.–5:00 p.m. S16 Neuromuscular and Clinical Neurophysiology (EMG): Clinical Trials and Therapy 3:15 p.m. S16.001 Lack of Correlation Between Biomarker and Clinical Outcome Measures in the Arimoclomol Inclusion Body Myositis Pilot Study   Mazen Dimachkie, Pedro Machado, Jianghua He, Yunxia Wang, April McVey, Mamatha Pasnoor, Philip Gallagher, Laura Herbelin, Jeffrey Statland, Adrian Miller, Linda Greensmith, Janice Holton, Michael Hanna, Richard Barohn 3:30 p.m. S16.002 Phase II Trial of Methotrexate in Myathenia Gravis   Mamatha Pasnoor, Laura Herbelin, Jianghua He, Mazen Dimachkie, Sharon Nations, Vera Bril, Annabel Wang, John Kissel, Ted Burns, David Saperstein, Jeffrey Rosenfeld, Aziz Shaibani, Carlayne Jackson, Andrea Swenson, James Howard, Namita Goyal, Matthew Wicklund, Joann Miller, Richard Barohn, MSG Methotrexate Study MG Group 3:45 p.m. S16.003 A Single-Blind, Randomized, Controlled Clinical Trial of Exercise in Ambulatory Spinal Muscular Atrophy (SMA) Patients   Jacqueline Montes, Samantha Kramer, Sally Dunaway, Megan Montgomery, Brendan Carr, Shirit Rosenberg, Douglas Sproule, Nancy Strauss, Carol Garber, Darryl De Vivo 4:00 p.m. S16.004 Is IVIg Therapy Warranted in Progressive Lower Motor Neuron Syndromes Without Conduction Block?   Neil Simon, Gretchen Ayer, Catherine Lomen-Hoerth 4:15 p.m. S16.005 The Effect of Tirasemtiv on Functional Status in Patients with ALS   Jeremy Shefner, Jacqueline Lee, Donna Barragan, Lisa Meng, Andrew Wolff, Jinsy Andrews 4:30 p.m. S16.006 Randomized Trial of Rifampicin in MSA: Effect on Autonomic Function   Wolfgang Singer, William Cheshire, Robert Fealey, Paola Sandroni, J. Ahlskog, Joseph Matsumoto, James Bower, Melinda Burnett, Andrew McKeon, Tonette Gehrking, Jade Gehrking, Eduardo Benarroch, Phillip Low 4:45 p.m. S16.007 Neuropathy Improvement Following Peripheral Blood Stem Cell Transplantation for POEMS Syndrome.   Chafic Karam, Christopher Klein, Angela Dispenzieri, Jayawant Mandrekar, P. James B. Dyck, Anita D’Souza, Michelle Mauermann

2O14 Scientific Abstract Listing and Annual Meeting Information

S17 Parkinson's Disease: Genetics and Epidemiology 3:15 p.m. S17.001 Mutations in the GCH1 Gene Are Associated with Parkinson Disease   Niccolò Mencacci, Ioannis Isaias, Martin Reich, Christos Ganos, James Polke, Jose Bras, Joshua Hersheson, Maria Stamelou, Alan Pittman, Alastair Noyce, Kin-Ying Mok, Thomas Opladen, Erdmute Kunstmann, Katie Sidle, Mary Sweeney, Henry Houlden, Hodecker Sybille, Amit Batla, Alexander Munchau, Jens Volkmann, Samuel Samnick, Giorgio Marotta, Anna Zecchinelli, Gianni Pezzoli, Andrew Lees, Paulo Alegria, Paul Krack, Florence Cormier, Suzanne Lesage, Alexis Brice, Peter Heutink, Thomas Gasser, Huw Morris, Steven Lubbe, Elisa Majounie, Raphael Gibbs, Andrew Singleton, John Hardy, Stephan Klebe, Kailash Bhatia, Nicholas, W Wood, None International Parkinson’s Disease Genomics Consort 3:30 p.m. S17.002 Age Specific Penetrance of the LRRK2 G2019S Mutation in the Michael J Fox Ashkenazi Jewish (AJ) LRRK2 Consortium   Karen Marder, Mingxin Tang, Roy Alcalay, Helen Mejia-Santana, Deborah Raymond, Anat Mirelman, Rachel SaundersPullman, Lorraine Clark, Laurie Ozelius, Avi Orr-Urtreger, Nir Giladi, Susan Bressman 3:45 p.m. S17.003 RER1: A Novel Regulator of AlphaSynuclein   Nikolaus McFarland, Hyo-Jin Park, Lauren Ricchiuti 4:00 p.m. S17.004 Apolipoprotein A1 Levels Are Associated with APOA1 Promoter Variation and Influence Parkinson’s Disease Risk   Christine Swanson, Katherine Li, Travis Unger, Michael Gallagher, Vivianna Van Deerlin, Pinky Agarwal, James Leverenz, John Roberts, Ali Samii, Rachel Goldmann Gross, Howard Hurtig, Jacqueline Rick, Daniel Weintraub, John Trojanowski, Cyrus Zabetian, Alice Chen-Plotkin 4:15 p.m. S17.005 Prevalence and Predictors of AntiParkinson Drug Use in a Nationally Representative Sample of Medicare Beneficiaries, 2006-2010   Nabila Dahodwala, Allison Willis, Pengxiang Li, Jalpa Doshi 4:30 p.m. S17.006 Serum Cholesterol, Statin, and Parkinson’s Risk in the Atherosclerosis Risk in Communities (ARIC) Study   Xuemei Huang, Alvaro Alonso, Xuguang Guo, David Umbach, Richard Mailman, Thomas Mosley, Honglei Chen 4:45 p.m. S17.007 Time Trends in the Incidence of Parkinsonism and Parkinson Disease in Olmsted County, Minnesota Over Thirty Years   Rodolfo Savica, Brandon Grossardt, James Bower, J. Ahlskog, Walter Rocca

S18 Aging, Dementia, and Cognitive and Behavioral Neurology: Behavioral Neuroscience 3:15 p.m. S18.001 Neuroeconomic Measures of Impaired Decision-Making in Frontotemporal Dementia   Winston Chiong, Kristie Wood, Andrew Kayser, Mark D’Esposito, Howard Rosen, Bruce Miller, Joel Kramer 3:30 p.m. S18.002 Strategic Problem Solving in Behavioral Variant Frontotemporal Dementia   Laura Baehr, Corey McMillan, Katya Rascovsky, John Powers, Lisa Burkholder, Murray Grossman 3:45 p.m. S18.003 A CSF Signature of Frontotemporal Lobar Degeneration with C9orf72 Repeat Expansions   William Hu, Jonathan Glass, Vivianna Van Deerlin, Murray Grossman, Kelly Watts, James Lah, John Trojanowski, Allan Levey 4:00 p.m. S18.004 Cholinergic Integrity and Visual Hallucinations in Parkinson Disease   Nicolaas Bohnen, Martijn Muller, Vikas Kotagal, Roger Albin, Kirk Frey 4:15 p.m. S18.005 Neuropsychological Profiles of Voltage-gated Potassium Channel Complex and Other Autoimmune Encephalopathies; More Than Memory Impairment   Michael Geschwind, Jeffrey Gelfand, Sarosh Irani, John Neuhaus, Sven Forner, Brianne Bettcher 4:30 p.m. S18.006 Predictors of Response to Propranolol for Social Functioning in Autism Spectrum Disorder   David Beversdorf, Rachel Zamzow, Brad Ferguson, Tamera Martin, Morgan Lewis, Janine Stichter 4:45 p.m. S18.007 SHANK3 Overexpression Causes Manic-like Behavior with Unique Pharmacogenetic Properties   Jimmy Holder, Huda Zoghbi

Scientific Sessions 3:15 p.m. S19.001 Good Vibrations: A Novel Method of Damping Acquired Pendular Nystagmus with Vibration   Shin Beh, Amir Kheradmand, Teresa Frohman, Darrel Conger, Amy Conger, Peter Calabresi, Laura Balcer, Elliot Frohman, David Zee 3:30 p.m. S19.002 A Novel Quantitative Bedside Test of Balance Function: the Video Visually Enhanced Vestibulo-ocular Reflex (VVOR)   David Szmulewicz, Hamish MacDougall, Elsdon Storey, Ian Curthoys, Michael Halmagyi 3:45 p.m. S19.003 Alice in Wonderland Syndrome: Presenting and Follow-up Characteristics   Grant Liu, Alessandra Liu, Jonathan Liu, Geraldine Liu 4:00 p.m. S19.004 Eye Movement Perimetry for Evaluation of Visual Field Loss in Patients with Glaucoma and Recovered Optic Neuritis   Matthew Thurtell, David Warren, Alice Xu, Andrew Papendieck, Michael Wall 4:15 p.m. S19.005 Evaluation of Face and Voice Perception and Recognition Impairments in Prosopagnosia   Ran (Richard) Liu, Raika Pancaroglu, Charlotte Hills, Bradley Duchaine, Jason Barton 4:30 p.m. S19.006 Vision Testing Is Additive to the Sideline Assessment of SportsRelated Concussion   Rachel Ventura, Zoe Marinides, Steven Galetta, James Clugston, Laura Balcer 4:45 p.m. S19.007 Capturing Episodic Vertigo   Miriam Welgampola, Corinna Lechner, Hamish Macdougall, Michael Halmagyi

S20 Pain and Palliative Care 3:15 p.m.  Presentation of Mitchell B. Max Award for Neuropathic Pain Recipient: Kathleen Foley, MD New York, NY

3:30 p.m. S20.002 ALS: Pain in Addition to Anything Else   Nathalie Guy, Catherine Cornut Chauvinc, Xavier Moisset, Pierre Clavelou 3:45 p.m. S20.003 Identifying Palliative Care Needs in the Neurological Intensive Care Unit   Claire Creutzfeldt, J Curtis 4:00 p.m. S20.004 DS-5565 for the Treatment of Diabetic Peripheral Neuropathic Pain: Randomized, Double-Blind, Placeboand Active Comparator-controlled Phase II Study   Aaron Vinik, Uma Sharma, Karen Feins, Ching Hsu, Domenico Merante 4:15 p.m. S20.005 Peripheral Edema and Weight Gain in Adult Patients with Painful Diabetic Peripheral Neuropathy (DPN) Receiving Gabapentin Enacarbil (GEn) or Pregabalin Enrolled in a Randomized Phase 2 Trial   Anne Calkins, Joseph Shurman, Mark Jaros, Richard Kim, Gwendoline Shang 4:30 p.m. S20.006 Botulinum Toxin for Muscle Cramps Associated with Diabetic Neuropathy: A DoubleBlind, Placebo-Controlled Study   Domenico Restivo, Antonino Pavone, Damiano Gullo, Stefano Jann, Riccardo Vigneri 4:45 p.m. S20.007 Virtual Family Meetings in the ICU Setting: Results from an Audiovisual Conferencing Intervention   Adam de Havenon, Casey Petersen, Ali Sultan-Qurraie, Robert Hoesch

S21 Neuro-rehabilitation and Neural Repair

S22 Neuro-oncology

3:15 p.m. S21.001 Randomized Controlled Trial of Constraint-induced Aphasia Therapy in Patients with Chronic Stroke   Jerzy Szaflarski, Jane Allendorfer, Angel Ball, Christi Banks, Aimee Dietz, Kimberly Hart, Christopher Lindsell, Amber Martin, Jennifer Vannest

3:15 p.m. S22.001 A Vaccine Targeting Mutant IDH1 Induces Antitumor Immunity   Michael Platten, Theresa Schumacher, Lukas Bunse, Felix Sahm, Stefan Pusch, Jasmin Quandt, Oliver Menn, Matthias Osswald, Angelika Riemer, Philipp Beckhove, Manuel Alexander Friese, Andreas von Deimling, Wolfgang Wick

3:30 p.m. S21.002 Measuring Health-related Quality of Life (HRQOL) During Inpatient Stroke Rehabilitation   Pasquale Frisina, Ann Kutlik, Kimberly Hreha, A. Barrett

3:30 p.m. S22.002 Neurocognitive Function (NCF) Substudy and Mini-Mental State Examination (MMSE) Results from the Randomized, Placebo-Controlled Phase III AVAglio Trial of Bevacizumab (BEV) Added to Radiotherapy (RT) and Temozolomide (TMZ) for Newly Diagnosed Glioblastoma   Jeffrey S Wefel, Olivier Chinot, Wolfgang Wick, Warren Mason, Roger Henriksson, Frank Saran, Ryo Nishikawa, Cedric Revil, Josep Garcia, Timothy Cloughesy

3:45 p.m. S21.003 Brain Structural and Functional Changes After Action Observation Therapy in Parkinson’s Disease Patients with Freezing of Gait   Federica Agosta, Elisa Canu, Elisabetta Sarasso, Mariano Gemma, Alessandro Meani, Antonietta Volonté, Lidia Sarro, Sebastiano Galantucci, Andrea Falini, Giancarlo Comi, Roberto Gatti, Massimo Filippi 4:00 p.m. S21.004 Neuroprotective and Neurorestorative Effects of Thymosin Beta4 Treatment After Traumatic Brain Injury   Asim Mahmood, Ye Xiong, Michael Chopp 4:15 p.m. S21.005 Recovery from Brain Injury After Prolonged Disorders of Consciousness: Outcome of Patients Admitted to Rehabilitation with 1-8 Year Follow-up   Douglas Katz, Meg Polyak, Daniel Coughlan, Emily Goff, Meline Nichols, Alexis Roche 4:30 p.m. S21.006 Comparison of the Checkerboard P300 Speller Versus the Row-Column Speller in Normal Elderly and an Aphasic Stroke Population   Jerry Shih, George Townsend, Dean Krusienski, Kevin Shih, Ryan Shih, Kristin Heggeli, Trevor Paris, James Meschia 4:45 p.m. S21.007 Individualized Treatment with Transcranial Direct Current Stimulation in Patients with Chronic Nonfluent Aphasia Due to Stroke   Priyanka Shah, Catherine Norise, Gabriella Garcia, Jose Torres, Olu Faseyitan, Roy Hamilton

3:45 p.m. S22.003 Overview of Arterial Thromboembolic Events (ATEs) in AVAglio, a Randomized, Placebo-controlled Phase III Trial of Bevacizumab, Radiotherapy and Temozolomide (BEV+RT/TMZ) for Newly Diagnosed Glioblastoma   Warren Mason, Timothy Cloughesy, Wolfgang Wick, Roger Henriksson, Frank Saran, Ryo Nishikawa, Sunita Dhar, Cedric Revil, Josep Garcia, Olivier Chinot 4:00 p.m. S22.004 Predicting Progressive Gangliogliomas: Early Identification of Those at Risk in a Sample of 156 Consecutive Patients Treated at the Barrow Neurological Institute   Glynnis Zieman, Christopher Dardis, Andrea Gomes, Adrienne Scheck, Jennifer Eschbacher, Lynn Ashby 4:15 p.m. S22.005 The Neurologic Assessment in Neuro-Oncology (NANO) Scale: A Tool to Assess Neurologic Function for Integration in the Radiologic Assessment in Neuro-Oncology (RANO) Criteria   Lakshmi Nayak, Lisa DeAngelis, Patrick Wen, Alba Brandes, Riccardo Soffietti, Nancy Lin, David Peereboom, Marc Chamberlain, David Macdonald, Evanthia Galanis, James Perry, Kurt Jaeckle, Minesh Mehta, Roger Stupp, Martin Van Den Bent, David Reardon 4:30 p.m. S22.006 Improved Progression Free Survival in 1p/19q Co-deleted Anaplastic Oligodendroglioma Treated with Both Chemotherapy and Radiation Therapy at Diagnosis   Jacob Mandel, Courtney Webre, Nicole Shonka, W K Yung, John De Groot

S23 MS and CNS Inflammatory Disease: Novel Therapeutics 3:15 p.m.  Presentation of John Dystel Prize for Multiple Sclerosis Research Recipient: Barry Arnason, MD Chicago, IL

3:45 p.m. S23.003 A Combination Trial of Estriol Plus Glatimer Acetate in Relapsing-Remitting Multiple Sclerosis   Rhonda Voskuhl, HeJing Wang, T.C. Jackson Wu, Nancy Sicotte, Angela Bates, Gary Beaver, John Corboy, Anne Cross, Suhayl Dhib-Jalbut, Corey Ford, Barbara Giesser, Dina Jacobs, Sharon Lynch, Andrew Pachner, Michael Racke, John Ratchford, Anthony Reder, John Rose, Dean Wingerchuk, Margaret Burnett, Chi Hong Tseng, Robert Elashoff 4:00 p.m. S23.004 Effect of Alfacalcidol on Fatigue in MS Patients: A Randomized, Doubleblind Study   Yoram Barak, David Magalashvili, Mark Dolev Dolgopiat, David Ladkani, Dalia Nitzani, Zeev Mazor, Anat Achiron 4:15 p.m. S23.005 STREAMS: A Phase 2 Clinical Trial of Autologous Mesenchymal Stem Cells in Active Multiple Sclerosis   Rehiana Ali, Stephen Marley, Renuka Palanicawandar, Francesco Dazzi, Richard Nicholas, Paolo Muraro 4:30 p.m. S23.006 The MIRROR Study: A Randomized, Double-blind, Placebo-controlled, Parallel-group, Dose-ranging Study to Investigate the Safety and MRI Efficacy of Subcutaneous Ofatumumab in Subjects with Relapsing-Remitting Multiple Sclerosis (RRMS)   Amit Bar-Or, Richard Grove, Daren Austin, Jerry Tolson, Susan Vanmeter, Eric Lewis, Per Solberg Sorensen 4:45 p.m. S23.007 Randomized Controlled Trial of CI Therapy for Progressive MS: Increased Real-world Function and Neuroplasticity on MRI   Victor Mark, Edward Taub, Gitendra Uswatte, Gary Cutter, David Morris, Staci McKay, Mary Bowman, Michelle Haddad, Tyler Rickards, Chelsey Sterling

4:45 p.m. S22.007 Ionizing Radiation Arrests Subventricular Zone Neural Precursors in G2/M without Affecting Long-Term Self-Renewal   Hongxin Chen, Sonia De Toledo, Matthew Goodus, Azzam Edward, Steve Levison, Nizar Souayah



Fast, Easy Registration Online  ·  AAN.com/view/AM14

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Tuesday April 29

S19 Neuro-ophthalmology/ Neuro-otology I



Tuesday, April 29

Current as of 2/13/2014

Hot Topics Plenary Session

5:30 p.m.–6:30 p.m.

F eatures translational research related to clinical issues of importance. Four outstanding physician-scientists provide summaries of their recent research findings and describe the clinical implications of the results. Moderator: Aleksandar Videnovic, MD, MSc

Member, Science Committee



Identification of a Unique Molecular and Functional Microglia Signature in Health and Disease Oleg Butovsky, PhD Brigham and Women’s Hospital/Harvard Medical, Boston, MA



The Global Epidemic of Stroke: Sounding the Alarm Jerome H. Chin, MD, PhD, MPH Alliance for Stroke Awareness and Prevention Project (ASAPP), San Anselmo, CA



Emerging Concepts in Chronic Traumatic Encephalopathy Dennis W. Dickson, MD Mayo Clinic, Jacksonville, FL



Functional Connectivity and Functional Imaging in Movement Disorders David Eidelberg, MD, FAAN Feinstein Institute for Medical Research, Manhasset, NY

For Full Abstracts and Bios for Plenary Speakers Visit AAN.com/view/SearchAM

80

2O14 Scientific Abstract Listing and Annual Meeting Information

Wednesday, April 30

Poster Session IV

P4  Poster Session IV First Authors stand by Posters from 7:30 a.m.–9:00 a.m.

7:30 a.m.–11:00 a.m.

Poster Discussion Session: MS and CNS Inflammatory Disease I Utilizing a guided tour format, topic experts will lead attendees around the ten posters in the poster discussion session and facilitate questions with poster authors during the 90-minute author stand-by time.

Autologous Hematopoietic Stem Cell Transplantation in Neuromyelitis Optica  Jodie Burton, Jan Storek, Fiona Costello, Peter Duggan, Luanne Metz

P4.002

Rate Evaluation of 25-Hydroxy-Vitamin D in Neuromyelitis Optica  Laurent Kremer, Ilhame Slassi Sennou, Nada Benkirane, Adil Araqi Houssaini, Nicolas Collongues, Jean Baptiste Chanson, Frederic Blanc, MarieCéline Fleury, Arnaud Theulin, Rose-Marie Javier, Jerome De Seze

P4.003

Laquinimod Prevents NMOIginduced Disease Exacerbation in a Model of Neuromyelitis Optica.  Azeb Argaw, Linnea Asp, Jingya Zhang, Patrick Waters, Liat Hayardeny Nisimov, Michael Levy, Gareth John

P4.004

Trial of C1-Esterase Inhibitor in Acute Relapses of Neuromyelitis Optica  Michael Levy, Maureen Mealy

P4.005

Analysis of the Treatment of Neuromyelitis Optica at the Hospital of the University of Pennsylvania Jose Torres, Amy Pruitt, Clyde Markowitz, Nabila Dahodwala

P4.006

Adoptive Transfer of T-cells Reactive to Aquaporin-4 Creates Neuromyelitis Optica Mouse Model  Michael Levy, Melina Jones, Hwa Huang, Maureen Mealy

P4.007

The Largest Genomics Study of NMO in History: Whole Genome Sequencing of 150 Patients with Neuromyelitis Optica  Benjamin Greenberg, Douglas Kerr, Tim Harris, Aaron DayWilliams, John Carulli

P4.008

Typical and Atypical Initial Presentations of Neuromyelitis Optica: A Retrospective Study  Juebin Huang, Burhan Chaudhry, Kimberly McDonald, V Vedanarayanan, Colette Parker, James Corbett, Robert Herndon

P4.009

The Spectrum of Brain MRI Abnormalities in Neuromyelitis Optica Spectrum Disorders  Juebin Huang, Burhan Chaudhry, Kimberly McDonald, V Vedanarayanan, Colette Parker, James Corbett, Robert Herndon

P4.010

Neuromyelitis Optica and Neuromyelitis Optica Spectrum Disorders: The Evaluation of 70 Patients Followed by Istanbul Bilim University, Department of Neurology  Burcu Altunrende, Ayca Altınkaya, Baris Topcular, Kocaslan Meryem, Sadik Server, Sinem Firtina, Sedef Yenice, Gulsen Akman-Demir

NEW! e  Poster Session: Aging, Dementia, and Cognitive and Behavioral Neurology II The ePoster session will feature a selection of posters to be presented digitally, rather than in the traditional format. Authors will be able to take advantage of the format to highlight compelling visual features such as images and videos. See poster map on page 47 for location.

P4.011

PET Amyloid Imaging with Florbetapir Predicts Cognitive Decline in the Oldest-Old  Dana Greenia, Claudia Kawas, Michelle Caunca, Szofia Bullain, Maria Corrada

P4.012

Assessing Brain System Dysfunction in Amnesic Mild Cognitve Impairment Through MRI-based Connectomics  Federica Agosta, Elisa Canu, Sebastiano Galantucci, Alessandro Meani, Giuseppe Magnani, Alessandra Marcone, Andrea Falini, Giancarlo Comi, Massimo Filippi

P4.013

Cerebral Blood Flow and White Matter Hyperintensities in Nondemented Elderly  Lisa Silbert, Hiroko Dodge, David Lahna, Nutta-on Promjunyakul, William Rooney, Deniz ErtenLyons, Jeffrey Kaye

P4.014

Genetic Influences of Survival in the Behavioral Variant of Frontotemporal Degeneration  David Irwin, Corey McMillan, Eunran Suh, Katya Rascovsky, Jon Toledo, Virginia Lee, John Trojanowski, Vivianna Van Deerlin, Murray Grossman

P4.015

Utility of Amyloid Neuroimaging in Clinical Practice Patricio Chrem Mendez, Gabriela Cohen, Julieta Russo, Marcos Fernandez Suarez, Jorge Campos, Griselda Russo, Janus Kremer, Alejandra Amengual, Silvia Vazquez, Ramon Leiguarda, Gustavo Sevlever, Ricardo Allegri

P4.016

Improved Accuracy of the Diagnosis of Early Alzheimer’s Disease Using Combined Measures of Hippocampal Volume and Sulcal Morphology Lorraine Hamelin, Cruz de Souza Leonardo, Fabian Corlier, Helene Corne, Marie Chupin, Bruno Dubois, Michel Bottlaender, Olivier Colliot, Marie Sarazin

P4.017

Presence of Microinfarcts at Autopsy Is Associated with Increased Rate of Gray Matter Atrophy on Antemortem MRI  Mekala Raman, Matthew Senjem, Jeffrey Gunter, Scott Przybelski, Prashanthi Vemuri, Melissa Murray, Bradley Boeve, David Knopman, Ronald Petersen, Joseph Parisi, Dennis Dickson, Clifford Jack, Kejal Kantarci



P4.018

Longitudinal Patterns of Brain Atrophy in Frontotemporal Lobar Degeneration Clinical Syndromes Compared with Alzheimer’s Disease Pilar Ferraro, Federica Agosta, Elisa Canu, Giuseppe Magnani, Alessandra Marcone, Andrea Falini, Giancarlo Comi, Massimo Filippi

P4.019

White-Matter Evidences of Corticospinal Pathway Involvement in Frontotemporal Dementia Chiara Crespi, Chiara Cerami, Alessandra Dodich, Alessandra Marcone, Nicola Canessa, Sandro Iannaccone, Massimo Corbo, Christian Lunetta, Elisa Scola, Andrea Falini, Stefano Cappa

P4.020

Whole Brain, Voxel Level Analysis of Grey Matter Volume and Time to Incident Mild Cognitive Impairment or Alzheimer’s Disease  Lubov Zeifman, William Eddy, Oscar Lopez, Lewis Kuller, Cyrus Raji, James Becker

Fast, Easy Registration Online  ·  AAN.com/view/AM14 81

Wednesday April 30

P4.001



Wednesday, April 30 General Neurology III P4.021

Lumbar Spine Manifestation of Intracranial Hypotension  Brion Reichler, Darius Melisaratos

P4.022

Case Report—Multi-focal Intracranial Tuberculoma in the Setting of Miliary TB in an Immunocompetent Patient  Ali Saeed, Gautam Sachdeva, Syed Hussain

P4.023

Anti-NMDA Receptor Encephalitis Presenting with Atrial Fibrillation  Olha Taraschenko, Josep Dalmau, Earl Zimmerman, Mary Ann McKee

P4.024

The Gender Divide in Multiple Sclerosis: A Review of the Environmental Factors Influencing the Increasing Prevalence of Multiple Sclerosis in Women  Rebecca Klein, Jodie Burton

P4.025

Population Based Study of Co-Morbidity of Neurological Autoimmune Diseases and Thyroid Disease in Buenos Aires, Argentina  Andres Villa, Florencia Aguirre, Luciana Melamud, Marianna Di Egidio, Ricardo Alonso, Raul Rey

P4.026

Lupus-Associated Transverse Myelitis Masquerading as Septic Shock  Rahul Dave, Ciro Ramos Estebanez

P4.027

Third Ventricular Tumors and Sudden Deterioration: Is Coronary Vasospasm a Missing Link? Marissa Kellogg, Holly Hinson

P4.028

Hypoxic Ischemic Brain Injury Following in Hospital Cardiac Arrest— Lessons from Autopsy  Harsh Gupta, Archana Hinduja, Sanjeeva Onteddu, Ju Dong Yang

P4.029

Multiple Cranial Neuropathy in Paraneoplastic Anti-Hu Antibody Syndrome  Thomas Schmidt, Andrew Solomon

P4.030

Dysganglionosis as a Cause of Idiopathic Gastroparesis. A New Way to its Diagnosis and Treatment  Ulrich Liebetrau, Volker Limmroth, Carl Eisenberger, Anke Brunn, A.J. Dormann

P4.031

Quality of Life in Liver Transplant Patients with Neurologic Complications.  Maria Gonzalez Toledo, Analia Calle, Fatima Pagani Cassara, Agustina Tamargo, Alejandro Thomson, Diego Nadile, Fernando Gruz, Vladimiro Sinay

P4.032

Brain and Liver Iron Accumulation Demonstrated by 1.5-tesla and 3-tesla MRI in Aceruloplasminemia  Koji Fujita, Yusuke Osaki, Masafumi Harada, Satoshi Kono, Hiroaki Miyajima, Yuishin Izumi, Ryuji Kaji

P4.033

Akinetic Mutism and Parkinsonian Features Progressing to Coma Following a Hypoxic Event with Extended Lucid Interval: Manifestations of Delayed Post-hypoxic Leukoencephalopathy Alden P. Doerner Rinaldi, Eliza Miller, Barry Czeisler, Joshua Willey, Crary John, Jan Claassen, Stephan Mayer, Sachin Agarwal

82

P4.034

A Winged Scapula and Dropped Wrist: Cervical Radiculomyelopathy as an Unusual Presenting Manifestation of Copper Deficiency  Sajish Jacob, Harsh Gupta, Robert Archer, Betul Gundogdu

P4.035 Metachromatic

Leukodystrophy Mistaken for Manganese Toxicity in a Patient with Common Variable Immunodeficiency: A New Triad of Devastating Disease?  Zubair Ahmed, Hesham Abboud, Edward Manno

P4.036

Treatment of Post-Influenza Vaccination-induced Acute Disseminated Encephalomyelitis (ADEM) with Plasma Exchange—a Case Report Mandeep Chahil, Clement Pillainayagam, Paul Schulz

P4.037

A Rare Case of Churg Strauss Syndrome associated with Cervical Spine and Brain Involvement  Shilpi Mittal, Agnes Acsadi, Lorinda Cruz, Taylor Aglio, Kirsten Ek, Santhanam Lakshminarayanan, Kristen Logee

P4.038

Neurology Telemedicine Interest in Arkansas  L Greenfield, Maryam Bashiri, Sukanthi Kovvuru

P4.039

Subacute Sclerosing Panencephalitis: Case study and Literature Review  Danny Estupinan, Nikolaus McFarland

P4.040

Thoracic Myelopathy Due to Hypertrophic Pachymeningitis Secondary to Adalimumab  Yefim Yushvayev-Cavalier, Warren Zeigler, Mary Ann McKee, Marjorie Bunch, Adolfo Ramirez Zamora

Movement Disorders: Parkinson’s Disease Biomarkers P4.041

Longitudinal Quantitative EEG Changes Correlate With Neuropsychological Assessment Decline  John Caviness, Joe Hentz, Erika Driver-Dunckley, Christine Belden, Jessica Powell, Michael Ahmadi, Charles Adler

P4.042

Glucocerebrosidase Enzyme Activity in GBA1 Mutation Parkinson Disease  Robert Ortega, Paola Torres, Sarah Boschung, Matthew Swan, Jeannie Soto-Valencia, Matthew Barrett, Brooke Johannes, Deborah Raymond, Lawrence Severt, Vicki Shanker, Susan Bressman, Gregory Pastores, Rachel Saunders-Pullman

P4.043

The BioFIND Study (Fox Investigation For New Discovery Of Biomarkers In Parkinson’s Disease): Design And Methodology  Un Kang, Roy Alcalay, Jennifer Goldman, Claire Henchcliffe, Penelope Hogarth, Paul Tuite, Tao Xie, Mark Frasier, Catherine Kopil, Lona Vincent, Nicole Willis, Cindy Casaceli, Alice Rudolph

P4.044

Evaluation of the Cutaneous Silent Period in Patients with Parkinson’s Disease  Serdar Tasdemir, Hakan Akgun, Mehmet Yucel, Semih Alay, Oguzhan Oz, Umit Ulas, Seref Demirkaya

P4.045

Association of Serum Cystatin C Levels on the Progression and Cognition in Parkinson’s Disease  Jing Chen, Chunfeng Liu

7:30 a.m.–11:00 a.m. P4.046

Defining Impaired Olfaction in Parkinson’s Disease: a Comparison of Methods.  Katherine Grosset, Naveed Malek, Sarah Marrinan, Nin Bajaj, Waiken Chan, Christina Banks, Huw Morris, Roger Barker, Thomas Foltynie, Nicholas, W Wood, Nigel Williams, Yoav Ben-Shlomo, David Burn, Donald Grosset

P4.047

An Aptamer-Based Screen of 1000+ Plasma Proteins for Diagnostic Biomarkers in Parkinson’s Disease  Benjamine Liu, Christine Swanson, Jacqueline Rick, Daniel Weintraub, Howard Hurtig, John Trojanowski, Alice Chen-Plotkin

P4.048

Plasma Long Chain Fatty Acids and Cognition in Parkinson’s Disease  Charles Murchison, Joseph Quinn, Brenna Cholerton, James Leverenz, Thomas Montine, Cyrus Zabetian, Kathryn Chung, Amie Peterson, Gene Bowman

Movement Disorders: Biomarkers and Treatment P4.049

In Vivo Gastric Detection of α-Synuclein Inclusions in Parkinson’s Disease  Alvaro Sanchez, Alberto Rabano, Maria-Jose Catalan, Fernando Canga, Servando Fernandez-Diez, Jaime Herreros-Rodriguez, Elvira Garcia-Cobos, Marina Mata Alvarez-Santull, Lydia LopezManzanares, Mosqueira Antonio J, Lydia Vela, Juan Lopez-Lozano, Eva Lopez-Valdes, Jose Antonio Molina

P4.050

Reduction in Post-Botulinum Toxin Flu-like Symptoms After Injection with Incobotulinum Toxin  Edwin George, Natalya Shneyder

P4.051

Antibody Mediated Movement Disorders and Their Differential Response to Immunomodulatory Therapy  Laura Bishop, Mustafa Siddiqui, Jessica Tate, Ihtsham Haq

P4.056

Physical Activity and Risk of Comorbid Depression with Parkinson Disease  Rui Liu, David Umbach, Yikyung Park, Xuemei Huang, Albert Hollenbeck, Aaron Blair, Honglei Chen

P4.057

Hereditary Spastic Paraplegia Due to a Novel Mutation in SPG11 Gene Presenting as Dopa Responsive Dystonia, Parkinsonism and Spasticity Subhashie Wijemanne, Joseph Jankovic

P4.058

The Relationship Between Motor Symptom Lateralization and NonMotor Symptoms (NMS) in Parkinson’s Disease Patients  Tarannum Khan, Raja Boddepalli, Denny Reyes

Movement Disorders: Hyperkinetic Disorders: Chorea and Tic Disorders P4.059

Acute Recurrent, Persistent Hypoglycemia-induced Chorea/Ballism in a Diabetic Patient on Hemodialysis Padmaja Vittal, Cynthia Comella, Kathleen Shannon

P4.060

Clinical Pyramidal Signs in a Series of Patients with Huntington’s Disease  Emilia Gatto, Virginia Laura Parisi, Ana Sanguinetti, Jose Luis Etcheverry, Gabriel Persi

P4.061

Estimating Huntington’s Disease (HD) Onset Using a Low-Cost Balance Assessment  Andrew Herndon, Jody Corey-Bloom, Marcella Scholl, Danielle Burt, Sean Huynh, Daniel Goble

P4.062

Estimate Huntington Disease Prevalence in Latin America  Emilia Gatto, Virginia Laura Parisi, Ana Sanguinetti, Gabriel Persi, Jose Luis Etcheverry

P4.063

P4.052

Primary CNS Lymphoma Presenting with a Rapidly Progressive Huntington’s Disease-Like Picture Hesham Abboud, Mohamed Hegazy, Rebecca Kuenzler, David Peereboom

P4.053

P4.065

A Comprehensive Approach to Parkinson’s Disease  Camille Vaughan, Anna Vandenberg, Felicia Goldstein, Lynn-Marie Trotti, Adriana Hermida, Mary Weeks, Stewart Factor Safety and Efficacy Study of ADS-5102 (amantadine HCl) Extended Release Capsules in Levodopa-Induced Dyskinesia (EASED Study)  Rajesh Pahwa, Caroline Tanner, Robert Hauser, Kapil Sethi, Stuart Isaacson, Daniel Truong, Lynn Struck, Mary Jean Stempien, Natalie McClure, Greg Went

P4.054

Economic Burden of Parkinson´s Disease in a Population of Monterrey, Mexico  Leonel Cantu-Martinez, Jesus Santos-Guzman, Ingrid EstradaBellman, Ramiro Mora-Villalvazo, Erika Salinas-Lezama, Hector Martinez

P4.055

Dietary Source of Vitamin D Is Associated with Parkinson Disease and Total Vitamin D Modifies the Genetic Association Between Vitamin D Receptor (VDR) Gene and Parkinson Disease Liyong Wang, Jeffery Vance, Marian Evatt, Lizmarie Maldonado, William Perry, James Ritchie, Gary Beecham, Eden Martin, Jonathan Haines, Margaret Pericak-Vance, William Scott

2O14 Scientific Abstract Listing and Annual Meeting Information

P4.064

Psychogenic Movement Disorders in Nonagenarians: Report of Two Cases  Stephen Reich, Melissa Armstrong, Ana Sanchez, Roy Fried A Case of Psychogenic Belching  Rainer Paine, Mark Hallett

P4.066

Social Functioning in Youth with Tourette Syndrome  Sarah Pearl Aronow-Werner, Heather Adams, Amy Vierhile, Alyssa Thatcher, Jonathan Mink, Erika Augustine

P4.067

Increased Dopamine Receptor Occupancy in People with Tourette Syndrome, Obsessive-Compulsive Disorder, and Neuroleptic Exposure  James Brasic, Harvey Singer, Eram Zaidi, Emily Gean, Anil Kumar, Anil Mathur, Rebecca MellingerPilgrim, Vanessa Raymont, Ahmet Dogan, Mohab Alexander, Marika Maris, Gerald Nestadt, Albert Gjedde, Dean Wong

Movement Disorders: Essential and Other Tremors P4.068

Clinical and Surface Electromyography (SEMG) Correlation in Tremors  Man Mohan Mehndiratta, Munish Kumar, Sanjay Pandey, Dinesh Sharma

Poster Session IV

P4.069

Decreased EAAT2 Protein Expression in the Essential Tremor Cerebellar Cortex  Sheng-Han Kuo, Michelle Lee, Etty Cortes, Jean Paul Vonsattel, Elan Louis, Phyllis Faust

P4.070

Genome-Wide Linkage Scan for Essential Tremor: The FASET Study  Lorraine Clark, Nora Hernandez, Ruth Ottman, Iuliana Ionita-Laza, Elan Louis

P4.071

Case Control Analysis of Spinocerebellar Ataxia (SCA) Loci Repeat Expansion Size in Essential Tremor (ET)  Lorraine Clark, Xinmin Liu, Xin Ye, Nora Hernandez, Ruth Ottman, Iuliana IonitaLaza, Elan Louis

P4.072

Tacrolimus-Induced Tremor: Switching from Immediate-release (IR-TAC) to LCP-Tacro Extended-release Tacrolimus (LCPT) Reduces Tremor and Improves Quality of Life  John Morgan, Anthony Langone, Vincenza Nigro, Shyamal Mehta, Kapil Sethi

P4.073

Shaky Handwriting: What Is the Rate of Decline During Prospective Follow-up of Essential Tremor?  Elan Louis, Monika Michalec, Art Gillman

P4.074

Case Study: First Reported Case of Interferon-alpha Induced Postural and Action Tremor  David Rydz, Madeleine Sharp, Stanley Fahn

P4.081

Eighteen Month Experience with Diaphragmatic Pacing in ALS: Outcomes, Efficacy and Adversities  Margaret Allred, Robert Baloh, Ashraf Elsayegh, Evgeny Tsimerinov, Abirami Muthukumaran, Anishee Shah, Richard Lewis

P4.090

P4.082

P4.091

Effects of Cough Augmentation on Pulmonary Morbidity, Survival, and Quality of Life in Patients with Amyotrophic Lateral Sclerosis in Respiratory Failure: A Randomised Trial  Muhammad Rafiq, Michael Bradburn, Alison Proctor, Christopher McDermott, Pamela Shaw

P4.083

Phrenic Nerve Conduction Studies as a Biomarker of Respiratory Insufficiency in ALS  Liberty Jenkins, Sarada Sakamuri, Jonathan Katz, Dallas Forshew, Lee Guion, Dan Moore, Robert Miller

P4.084

Vitamin D Is a Prognostic Factor of Amyotrophic Lateral Sclerosis and Confers Protection to Motoneurons in Vitro  Camu William, Boris Tremblier, Carine Plassot, Sebastien Alphandery, Celine Salsac, Nicolas Pageot, Raul JuntasMorales, Frederique Scamps, Jean Pierre Daures, Cedric Raoul

P4.085

ALS: Trials and Biomarkers

Serum Creatinine, a Biomarker for Muscle Mass in Amyotrophic Lateral Sclerosis (ALS), Predicts Loss of Ambulation Measured by ALS Functional Rating Scale-Revised Walking Item Score (ALSFRS-Rw)  Benjamin Brooks, Michael Fischer, Mohammed Sanjak, Scott Holsten, Boris Kandinov, William Bockenek, Elena Bravver, Urvi Desai, John Scott Story, Thomas Pacicco, Scott Lindblom, Velma Langford, Kathryn Wright, Amber Ward, Nicole Lucas, Nicole Smith, Mindy Nichols, Cynthia Lary, Joanne Nemeth, Priscilla Russo

P4.077

P4.086

P4.075

Tremor Assessment: Correlation Between Clinical and Functional Performance Tests Munish Kumar, Man Mohan Mehndiratta, Sanjay Pandey

P4.076

Functional Balance Difficulty in Essential Tremor: The Role of Cognition  Ashwini Rao, Arthur Gilman, Elan Louis

Tirasemtiv Amplifies Skeletal Muscle Response to Nerve Activation in Humans  Fady Malik, Richard Hansen, Vipin Vijayakumar, Stoltz Randall, Roger Enoka, David Morgans, Andrew Wolff

P4.078

A Pilot Trial of High Frequency High Dose Granulocyte Colony Stimulating Factor (GCSF) in Patients with Amyotrophic Lateral Sclerosis (ALS)  Tuan Vu, Terry McClain, Chuanhai Cao, Natalie Tucker, Brittany Golden, Lara Katzin, Clifton Gooch

P4.079

Safety and Tolerability of Systemic Beta-2-Adrenergic Agonist (Albuterol) as Pharmacological Therapy in Non-Invasive Ventilation (NIV) -supported Amyotrophic Lateral Sclerosis (ALS)Patients with Chronic Respiratory Failure Benjamin Brooks, Boris Kandinov, Velma Langford, Scott Lindblom, Mohammed Sanjak, Kathryn Wright, Amber Ward, Scott Holsten, Michael Fischer, Nicole Lucas, Nicole Smith, Mindy Nichols, Cynthia Lary, Joanne Nemeth, Priscilla Russo, William Bockenek, Elena Bravver, Urvi Desai, John Scott Story, Thomas Pacicco

P4.080

Bilateral Phrenic Nerve Pacing (PNP) in Amyotrophic Lateral Sclerosis (ALS) Patients: The Mayo Clinic Current Experience  Mohamed Kazamel, Ronald Reeves, Eric Sorenson

A Clinical Demonstration of an EEG Brain-Computer Interface (BCI) for ALS Patients (VA Cooperative Study #567): Enrollment, Retention, and Adherence  Richard Bedlack, Robert Ruff, Domenic Reda, Theresa Vaughan, Helen Shi, Katya Hill, Robert Ringer, Patricia Banks, Tamara Paine, Jonathan Wolpaw

Anterior Horn Cell Disease: Biomarkers P4.087

Sensory-motor Circuit Dysfunction in Adult Ambulatory SMA Type 3 Patients  Claudia Chiriboga, Louis Weimer, Jonathan Marra, Nicole Holuba LaMarca, Jacqueline Montes, Sally Dunaway, George Mentis, Brian McCabe, Darryl De Vivo

P4.088

A Significant Increase of Apparent Diffusion Coefficients in Corticospinal Tracts Differentiates Amyotrophic Lateral Sclerosis from Cervical Spondylotic Myelopaty Yuka Koike, Masato Kanazawa, Kensi Terajima, Kei Watanabe, Naoto Endo, Takayoshi Shimohata, Masatoyo Nishizawa

P4.089

Excessive Daytime Sleepiness Does Not Predict the Degree of Sleep Disordered Breathing in ALS: An Autonomic Dysfunction Matrix  Urvi Desai



Chronological Changes in Cardiac Sympathetic Function in Patients with Ayotrophic Lateral Sclerosis: An Analysis Using Cardiac I-123-MIBG Scintigraphy  Yuji Tanaka, Megumi Yamada, Akihiro Koumura, Yuichi Hayashi, Akio Kimura, Takashi Inuzuka Familial Amyloid Polyneuropathy Presenting as Atypical Lower Motor Neuron Disease: A Case Report  Fabrizio Salvi, Plasmati Rosaria, Francesca Pastorelli, Claudio Rapezzi

P4.092

Uric Acid in Amyotrophic Lateral Sclerosis: No Effect on Outcome in a Population-based Series Antonio Canosa, Andrea Calvo, Davide Bertuzzo, Galmozzi Francesco, Cugnasco Paolo, Pisano Fabrizio, Giancarlo Logroscino, Cristina Moglia, Enrica Bersano, Letizia Mazzini, Adriano Chio

P4.093

Sexual Dimorphism in ALS  Peter Bede, Marwa Elamin, Susan Byrne, Orla Hardiman

P4.094

Subscales of the ALS Functional Rating Scale (ALSFRS-R) as Determinants of Survival in Amyotrophic Lateral Sclerosis (ALS)  Katya Rascovsky, Sharon Xie, Ashley Boller, Xiaoyan Han, Leo McCluskey, Lauren Elman, Murray Grossman

P4.095

Time to Generalization as a Predictor of Prognosis in ALS. Rosanna Tortelli, Massimiliano Copetti, Federica Siena, Rosa Cortese, Rosa Capozzo, Fabio Pellegrini, Isabella Simone, Giancarlo Logroscino

P4.101

Magnetic Resonance Imaging Brachial Plexus Alterations in ALS Patients  Edoardo Spinelli, Gerevini Simonetta, Federica Agosta, Nilo Riva, Elisabetta Pagani, Andrea Falini, Giancarlo Comi, Massimo Filippi

P4.102

Predominantly C8 Myotomal Electrodiagnostic Findings in Hirayama Disease  Timothy Rust, William Arnold, Miriam Freimer

P4.103

Electrical Impedance Myography for the Evaluation of the Tongue Musculature in Amyotrophic Lateral Sclerosis.  Seward Rutkove, Sanjana Shellikeri, Yana Yunusova, Jordan Green, Lorne Zinman

P4.104

Functional Connectivity Measured by Spectral EEG as Potential Biomarker for Amyotrophic Lateral Sclerosis  Parameswaran Iyer, Bart Michaels, Edmund Lalor, Richard Reilly, Orla Hardiman, Orla Hardiman

P4.105

Multiple System Atrophy and Amyotrophic Lateral Sclerosis in a Family with Hexanucleotide Repeat Expansions in C9orf72  Jill Goldman, Cheryl Waters, Hiroshi Mitsumoto, Thomas Brannagan, Stephanie Cosentino, Edward Huey, ShengHan Kuo

Neuromuscular: Electrodiagnostic P4.106

Differences in Denervation Patterns Between Patients with Limb Onset and Bulbar Onset ALS  Rocio Garcia Santibanez, Stephen Scelsa

Can Follow-up Electrodiagnostic Studies in Patients with CIDP That Improved Following IGIV-C Treatment Predict Relapse After Treatment Discontinuation?  Russell Chin, Chunqin Deng, Vera Bril, Norman Latov, Hans Hartung, Ingemar Merkies, Peter Donofrio, Pieter Van Doorn, Marinos Dalakas

P4.097

Voxel-based Morphometry (VBM) Study in ALS (Amyotrophic Lateral Sclerosis): Temporal Cortical Damage as a Prognostic Marker  Milena Albuquerque, Helen Andrade, Cynthia Silva, Anamarli Nucci, Marcondes Franca, Jr.

P4.107

P4.098

P4.108

P4.096

Cognitive Changes and White Matter Tract Damage in the Motor Neuron Disease Spectrum  Elisa Canu, Federica Agosta, Edoardo Spinelli, Nilo Riva, Massimiliano Copetti, Adriano Chiò, Stefano Messina, Sandro Iannaccone, Andrea Calvo, Vincenzo Silani, Andrea Falini, Giancarlo Comi, Massimo Filippi

P4.099

Non-invasive Imaging of Transplanted Neural Stem Cell Survival in Amyotrophic Lateral Sclerosis Amit Srivastava, Sarah Gross, Piotr Walczak, Camille Bulte, Nicholas Maragakis, Jeff Bulte

P4.100

Cortical Hemodynamics Assessment in ALS During Cognitive Testing Using Functional Near Infrared Spectroscopy (fNIR)  Tooba Fayyaz, Jillian Edwards, Lauren Scull, Hasan Ayaz, Patricia Shewokis, David Libon, Anahita Deboo, Terry Heiman-Patterson

Clinical and Neurophysiological Spectrum of Peripheral Neurotoxicity in Patients with CD30Positive Malignancies, Treated with Brentuximab Vedotin.  Rosaria Plasmati, Francesca Pastorelli, Fabrizio Salvi Characteristics and Differential Diagnosis of Neuropathy in a Tertiary Neuromuscular Clinic  Hui Gong, Amaiak Chilingaryan, Grigor Harutunian, Nazely Ashikian, Said Beydoun

P4.109

The Neurohysiological Phenotype Of AH-TTR Amiloidoses  Francesca Pastorelli, Rosaria Plasmati, Claudio Rapezzi, Fabrizio Salvi

P4.110

Evaluation of Conduction Slowing in Amyotrophic Lateral Sclerosis: A Novel Approach  Zubeda Sheikh, Ankit Pahwa, Hongxin Chen, Nizar Souayah

P4.111

IVIG Responsive Motor Neuropathy in the legs: A Diagnostic Challenge  Eliz Agopian, Dale Lange

P4.112

Absence of Spontaneous Activity in Cervical Paraspinal Musculature in Patients with Multifocal Motor Neuropathy/Motor Neuropathy Nuri Jacoby, Russell Chin, Bridget Carey, Jennifer Langsdorf, Naomi Feuer, Norman Latov

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Wednesday April 30



First Authors stand by Posters from 7:30 a.m.–9:00 a.m.



Wednesday, April 30 P4.113

Diagnostic Utility of Repetitive Nerve Stimulation Test of the Trapezius Muscle in Amyotrophic Lateral Sclerosis  Yuki Hatanaka, Takashi Chiba, Hidehiko Okuma, Takamichi Kanbayashi, Midori Kuwabara, Mana Higashihara, Masahiro Sonoo

P4.114

A Standardized Grading System for Ulnar Neuropathy at the Elbow.  Ebinehita Arhebamen, Faten Abu Ghazal, Dilip Pandey, Lawrence Zeidman

P4.115

Association of Autonomic Symptoms in Carpal Tunnel Syndrome with Abnormalities in Sympathetic Skin Responses  Anibal Lugo, Faisal Ahmad, Lonni Schultz, Jose Garcia, Abdulrahman Alwaki, Naganand Sripathi

Neuropathy: Pathogenesis and Diagnostic Testing P4.116

Reduced Neurofilament Expression in Cutaneous Nerve Fibers of CMT2E Patients  Chiara Pisciotta, Yunhong Bai, Kathryn Brennan, Tiffany Grider, Shawna Feely, Suola Wang, Steven Moore, Michael Shy

P4.117

Characteristics of Patients Evaluated for Small Fiber Neuropathy with Skin Biopsy  David Saperstein, Todd Levine, Glenn Lopate, Mamatha Pasnoor, Kayla Newby

P4.118

Comparison of Epidermal Nerve Fiber Density and Quantitative Sudomotor Axon Reflex in Neuropathy Diagnosis  Ahmad Abuzinadah, Patricia Kluding, Douglas Wright, Linda D’Silva, Janelle Ryals, Bill Hendry, Omar Jawdat, Laura Herbelin, April McVey, Richard Barohn, Mazen Dimachkie, Mamatha Pasnoor

P4.119

Characterisation and Diagnostic Evaluation of Chronic Polyneuropathies Induced by Oxaliplatin and Docetaxel Comparing Skin Biopsy to Quantitative Sensory Testing and Nerve Conduction Studies  Thomas Krøigård, Henrik Schrøder, Camilla Qvortrup, Lise Eckhoff, Per Pfeiffer, David Gaist, Soren Sindrup

P4.120

Comparison of CIDP and MGUS Associated Neuropathy Patients  Nuha Alkhawajah, Samantha Dunnigan, Vera Bril

P4.121

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Skin Biopsies Gene Expression Analysis Thierry Kuntzer, Adrian Panaite, Puttini Stefania, Susanne Renaud, Andreas Steck

P4.122

Chronic Immune-Mediated Demyelinating Polyneuropathy After Cetuximab  Sarah Kranick, Tanya Lehky, Christine Chung, Hyunseok Kang

P4.123

Peripheral Neuropathy in Primary Sjögren’s Syndrome Camila Leijoto, Osvaldo Nascimento, Frederico Prado, Victor Kosac, Caroline Bittar, Giseli Quintanilha, Carlos Bruno Nogueira, Felipe Vianna

84

P4.124

Peripheral Neuromuscular Manifestations of Sarcoidosis Lipika Nayak, Brennen Bittel, Yunxia Wang, Mazen Dimachkie, Laura Herbelin, April McVey, Richard Barohn, Mamatha Pasnoor

P4.125

Monofocal Motor Neuropathy: A Case Series  Dipika Aggarwal, Mamatha Pasnoor, Laura Herbelin, Mazen Dimachkie, Richard Barohn, April McVey

MS and CNS Inflammatory Disease: Biomarkers P4.126

Cerebrospinal Fluid Protein Expression Profiles in Benign and Aggressive Multiple Sclerosis  Ying Liu, Marwan Alahiri, Shivani Agarwal, Saud Sadiq

P4.127

Extracellular Vesicles Isolated by Cerebrospinal Fluid as Biomarkers of Inflammation in Multiple Sclerosis and Inflammatory Neurological Diseases Paolo Ragonese, Maria Antonietta Mazzola, Fabiana Geraci, Giuseppina Turturici, Giulia Musso, Rosaria Tinnirello, Vincenzina Lo Re, Sabrina Realmuto, Marianna Lo Re, Paolo Aridon, Giuseppe Salemi, Gabriella Sconzo, Giovanni Savettieri

P4.128

Recirculating Phagocytes Are a Novel Source of Biomarkers for Brain Injury  Ramesh Nayak, Timothy Vollmer, Roberto Bomprezzi, Raymond Jacolik

P4.129

CSF Biomarkers in Tumefactive Multiple Sclerosis and Other Disease Subtypes  Ayse Altintas, Hayrettin Tumani, Sinem Yazici, Vera Lehmensiek

P4.130

Is KIR4.1 Antibody a Marker of Multiple Sclerosis ?  Elodie Nerrant, Mahmoud Charif, Xavier Ayrignac, Clarisse Carra-Dalliere, Giovanni Castelnovo, Celine Salsac, Cedric Raoul, Jean Francois Eliaou, Pierre Labauge, Thierry Vincent

P4.131

JCV Antibody Positivity and Status Switching Depends on Assay Cutpoint  Florian Deisenhammer, Micheal Auer

P4.132

Changes in Immunological Biomarkers in Patients with RelapsingRemitting Multiple Sclerosis Treated with Interferon Beta-1a  Xin Zhang, Yazhong Tao, Bianca Weinstock-Guttman, Robert Zivadinov, Brooke Hayward, Fernando Dangond, Silva Markovic Plese

P4.133

A Multicentric Crosssectional Study of the Usefulness of Cerebrospinal Fluid-Glial Fibrillary Acidic Protein (CSF-GFAP) in the Diagnosis and Prognosis of Inflammatory Demyelinating Diseases  Shuhei Nishiyama, Tatsuro Misu, Yuko Shimizu, Kazumasa Yokoyama, Takashi Kageyama, Yoshiki Takai, Rina Takano, Toshiyuki Takahashi, Juichi Fujimori, Shigeru Satoh, Ichiro Nakashima, Yasuto Itoyama, Kazuo Fujihara, Masashi Aoki

P4.134

B Cell Subsets in the Cerebrospinal Fluid of Multiple Sclerosis Patients  Christopher Sears, Jerry Lin, Alexandra Berman, Saud Sadiq

P4.135

Reduced Level of Sialylated IgG Antibody in the CSF of Patients with Multiple Sclerosis  Xiaoli Yu, Kathryn Dennison, Tiffany Pointon, Timothy Vollmer

7:30 a.m.–11:00 a.m. P4.136

CSF Isoelectric Focusing Differentiates Multiple Sclerosis from Other CNS Autoimmune Disorders Abdulradha Alqallaf, Shitiz Sriwastava, Fen Bao, Evanthia Bernitsas, Erica Errigo, Alexandros Tselis, Scott Millis, Christina Caon, Omar Khan

P4.137

Can inflammatory Markers from CSF be Helpful in Diagnosis of Multiple Sclerosis?  Zuzana Matejcikova, Hana Prikrylova-Vranova, Jana Klosova, Vladimira Sladkova, Jana Zapletalova, Jan Mares, Petr Kanovsky

P4.138

Update on MSPrecise: A Novel Diagnostic Test for Multiple Sclerosis  Nancy Monson, Eric Eastman, Douglas Bigwood, Mikhail Levin, William Rounds, Lindsay Cowell, Benjamin Greenberg

P4.139

Detection of Anti-natalizumab Antibodies in Treated Multiple Sclerosis Patients Using a Biacore™ Platform Fronda Anna, Ebrima Gibbs, Tariq Aziz, Joel Oger

P4.140

A One Year Follow-up of JCV Serology with Index Values in a French Natalizumab Treated Multiple Sclerosis Cohort  Olivier Outteryck, Hélène Zephir, Arnaud Kwiatkowski, Albert Verier, Didier Ferriby, Marine Viallet, Philippe Devos, Jean-Bertin N’Kuendjo, Olivier Derepeer, Patrick Hautecoeur, Patrick Vermersch

P4.148

Pharmacoeconomic and Clinical Characteristics in Patients with Multiple Sclerosis Treated with Disease Modifying Therapies: PEARL—24 Months Results  Sylia Moser, Sonja Ortler, Tom van Lokven, Tjalf Ziemssen

P4.149

Estimated Productivity Loss amongst U.S. Employees with Multiple Sclerosis  Slaven Sikirica, Huanxue Zhou, Vivian Herrera, Jinhee Park, Rahul Sasane

P4.150

The Impact of Spasticity Severity on Healthcare Utilization Among MS Patients: A Large-Scale Six-year Follow-up Study  Tuula Tyry, Amber Salter, Joan Largent, Ruth-Ann Marrie

P4.151

Substantial Declines in Rates of Hospitalization in Multiple Sclerosis: A Population-based Study Ruth-Ann Marrie, Nancy Yu, Aruni Tennakoon, James Marriott, Michael Cossoy, Lawrence Elliott, James Blanchard

P4.152

MS Related Employment in Germany After the Introduction of Disease Modifying Drugs  Alexei Korchounov

P4.153

Nursing Home MS Residents Experience Less Stress and Pessimism Compared to Home-Based NonAmbulatory MS Patients.  Zilfah Younus, Irfan Ahsan, Sahil Gupta, Katelyn Kavak, Barbara Teter, Bianca Weinstock-Guttman

P4.141

P4.154

P4.142

MS and CNS Inflammatory Disease: Pregnancy and Hormonal Influences

Anti-JC Virus Antibody Prevalence in Canadian MS Patients  Virender Bhan, Yves Lapierre, Mark Freedman, Pierre Duquette, Daniel Selchen, Vladimir Migounov, Len Walt, Annie Zhang Cerebrospinal Fluid Mononuclear Phagocytes Are Decreased in Number and Express Less IL-10 in Multiple Sclerosis Compared to Values Seen with Normal Controls  Shivani Agarwal, Irene Jarchum, Ying Liu, Saud Sadiq

P4.143

Fetuin-A, a Cerebrospinal Fluid (CSF) Biomarker of Multiple Sclerosis (MS) Disease Activity, Promotes Immune Cell Infiltration into the CNS  Lena Bell, Violaine Harris, Mark Landy, Kristi Clark, Saud Sadiq

P4.144

Association Between Immune Cell Neurotrophins Levels and Subcortical Grey Matter Volume in Multiple Sclerosis Patients  Alicja Kalinowska-Lyszczarz, Mikolaj Pawlak, Slawomir Michalak, Wlodzimierz Paprzycki, Wojciech Kozubski

Cost and Impact Care of MS P4.145

The Economic Impact of Functional Impairment Among Respondents with Multiple Sclerosis: Findings from the US Medical Expenditure Panel Survey Ravi Iyer, Matthew Sussman, Monica Fay, Terrie Livingston, Glenn Phillips, Joseph Menzin

P4.146

Peginterferon Beta-1a Reduces Relapse-Associated Costs in Patients with Relapsing-Remitting Multiple Sclerosis  Ken O’Day, Kellie Meyer, Matt Mitchell, Sonalee Agarwal, Elizabeth Kinter

P4.147

Cost Sharing Among Persons with MS  Eric Cheng, Vinita Dora, Miriam Ayad, Alex Chen, Annette Langer-Gould, Susan Ettner

2O14 Scientific Abstract Listing and Annual Meeting Information

Satisfaction with Multiple Sclerosis Care in Daily Practice of Patients Without an Immunmodulating Therapy—Results of a Patient Survey (FOLLOW)  Volker Heeschen

P4.155

Birth Outcomes In Newborns Fathered By Men With Multiple Sclerosis Exposed To Disease-Modifying Drugs Ellen Lu, Feng Zhu, Yinshan Zhao, Mia van der Kop, Anne Synnes, Leanne Dahlgren, Dessa Sadovnick, Anthony Traboulsee, Helen Tremlett

P4.156

Gestational Exposure to Natalizumab and Pregnancy Outcomes— Results from a Prospective Cohort with Relapsing Remitting Multiple Sclerosis  Neda Ebrahimi, Sandra Herbstritt, Ralph Gold, Lilyana Amezcua, Gideon Koren, Kerstin Hellwig

P4.157

Pregnancy and Fetal Outcomes After Paternal Exposure to Disease Modifying Drugs for Multiple Sclerosis  Maria Pia Amato, Marta Giannini, Emilio Portaccio, Angelo Ghezzi, Bahia Hakiki, Luisa Pasto’, Lorenzo Razzolini, Chiara Pecori, Andrea Sturchio, Laura De Giglio, Carlo Pozzilli, Damiano Paolicelli, Maria Trojano, Maria Marrosu, Francesco Patti, Gian Luigi Mancardi, Claudio Solaro, Rocco Totaro, Maria Tola, Giovanna De Luca, Alessandra Lugaresi, Lucia Moiola, Vittorio Martinelli, Giancarlo Comi

P4.158

Serum Anti-Müllerian Hormone Levels in Reproductive-age Women with Relapsing Remitting Multiple Sclerosis  Kerstin Hellwig, Susanne Kollar, Gisa Ellrichmann, Darryl Nousome, Ingo Kleiter, Ralf Gold, Jan Thoene

Poster Session IV

P4.159

Pregnancy Decisionmaking for Women with Multiple Sclerosis  Barbara Teter, Katelyn Kavak, Karen Zakalik, Channa Kolb, Patricia Coyle, Bianca Weinstock-Guttman

P4.160

Reproductive Attitudes and Pregnancy in Females with Multiple Sclerosis: Outcomes and Exposure to Disease-Modifying Drugs  Ayse Altintas, Bjar Najar, Gokcen Gozubatik-Celik, Sukriye Menku

P4.161

Updated Pregnancy Outcomes in Patients and Partners of Patients in the Teriflunomide Clinical Trial Program Lily Jung Henson, Myriam Benamor, Philippe Truffinet, Bernd Kieseier

P4.162

Influence of Sex Hormone Ratios on the Clinical Course of Multiple Sclerosis: A Case Study After the First Year of Follow Up.  Dimitrios Kitsos, Charis Liapi, Sotirios Tsiodras, Antonios Poulios, Konstantine Voumvourakis

P4.163

Menopause in a Longitudinal Clinical Cohort of Women with Multiple Sclerosis.  Riley Bove, Brian Healy, Alexander Musallam, Nafiseh Alsharif, Bonnie Glanz, Tanuja Chitnis

P4.164

Differencies in the Severity of Multiple Sclerosis Within Gender Determinated by Age at Onset Jimena Míguez, Juan Ignacio Rojas, Liliana Patrucco, Edgardo Cristiano

Cognition in MS P4.165

Mismatch Negativity Links to Information Processing in Multiple Sclerosis (MS)  Felicia Jackson, Leigh Charvet, Maria Amella, Greg Proudfit, Lauren Krupp

P4.166

Cognitive Dysfunction in Patients with Multiple Sclerosis Is Related with Apathy and Depression, But Not Subjective Fatigue  Masaaki Niino, Nobuhiro Mifune, Susumu Kusunoki, Yusei Miyazaki, Seiji Kikuchi

P4.167

Presence and Significant Determinants of Cognitive Impairment in a Large Sample of Patients with Multiple Sclerosis  Martina Borghi

P4.168

Predictivity of Executive Functions in Episodic Memory in Multiple Sclerosis  Rekha Barthelemy, Bruno Lenne, Dephine Leuse, Arnaud Kwiatkowski, Patrick Hautecoeur

P4.169

The Symbol Digit Modalities Test (SDMT) Has Been the Standard Cognitive Measure Used in Multiple Sclerosis (MS) Clinical Trials: How Does It Correlate with Computerized Cognitive Screening Tools?  Myassar Zarif, Mark Gudesblatt, Barbara Bumstead, Marijean Buhse, Lori Fafard, Cynthia Sullivan, Jeffrey Wilken, Glen Doniger, Juskaran Chahda

P4.170

Cognitive Changes During and After MS Relapses—6 Months FollowUp  Katrin Gross-Paju

P4.171

Cognitive Evolution in Tysabri (natalizumab)-Treated Multiple Sclerosis Patients  Francois Jacques, Brian Harel, Adrian Schembri, Joanne Gale

P4.172

Effects of Natalizumab on Cognition and Neurodegeneration in Relapsing-Remitting Multiple Sclerosis  Garrick Talmage, Oscar Coppes, Ashley Finch, Christina Sprayberry, Adil Javed, Jacqueline Bernard

P4.181

P4.173

P4.182

Multiple Sclerosis and Driving: Cognitive Profile Correlation to Patient Self-Reported Driving  Mark Gudesblatt, Myassar Zarif, Barbara Bumstead, Marijean Buhse, Smitha Thotam, Lori Fafard, Jennifer Kalina, Cynthia Sullivan, Jeffrey Wilken, Glen Doniger

MS and CNS Inflammatory Disease: Quality of Life P4.174

Quality of Life and Fatigue in Radiologically Isolated Syndrome Christine Lebrun Frenay, Mikael Cohen, Pierre Clavelou

P4.175

Cognition and Grey Matter Atrophy Are Predictive of Health Related Quality of Life in Early Treated Patients with Clinically Isolated Syndrome Mikael Cohen, Bruno Brochet, Pierre Clavelou, Emmanuelle Lepage, Patrick Vermersch, Ayman Tourbah, Thibault Moreau, Christine Lebrun Frenay

P4.176

Health-Related Quality of Life in US Patients with Relapsing-Remitting Multiple Sclerosis (RRMS) Treated with Delayed-Release Dimethyl Fumarate: An Integrated Analysis of the Phase 3 DEFINE and CONFIRM Studies  Mariko Kita, Robert Fox, Ralf Gold, Sujata Sarda, Ravi Iyer, Timothy Niecko, Leslie Meltzer, J. Theodore Phillips

P4.177

Peginterferon Beta-1a Treatment Reduces the Impact of Multiple Sclerosis Relapse and Disability Progression on Health-Related Quality of Life: Results from the ADVANCE Trial  Elizabeth Kinter, Shien Guo, Arman Altincatal, Irina Proskorovsky, Glenn Phillips, Bjorn Sperling

P4.178

Two-Year Interim Analysis of Quality of Life in Patients with RelapsingRemitting Multiple Sclerosis (RRMS) treated with Delayed-Release Dimethyl Fumarate in the ENDORSE Study Mariko Kita, Robert Fox, Ralf Gold, Gavin Giovannoni, J. Theodore Phillips, Sujata Sarda, Macaulay Okwuokenye, Jessica Kong, Ray Zhang, Vissia Viglietta, Sarah Sheikh, Ludwig Kappos

P4.179

Interim Results of the Swiss Post Marketing Surveillance Monitoring Quality of Life and Treatment Satisfaction in Patients with Relapsing-Remitting Multiple Sclerosis (SWISSASCENT) Adam Czaplinski, Emilie Jaquiery, Petra Stellmes, Simon Ramseier, Andreas Baumann, Oleg Kurlandchikov, Christian Berger, Michel Chofflon, Franziska Lieder, Sandra Gass, Thomas Maier

P4.180

Patient-reported Quality of Life in the BENEFIT Trial  Gilles Edan, Ludwig Kappos, Xavier Montalban, Mark Freedman, Hans Hartung, David Miller, Frederik Barkhof, Julia Hermann, Vivian Lanius, Christoph Pohl, Rupert Sandbrink, Dirk Pleimes



Multiple Sclerosis: the Need to Understand Patients’ Quality of Life in a Latin American Country  Sandra Vanotti, Natalia Ciufia, Cecilia Yastremiz, Maria Saladino, Nora Fernandez Liguori, Alberto Yorio, Fernando Caceres Health-Related Quality of Life in Relapsing-Remitting Multiple Sclerosis (RRMS): Comparison with Other Medical Conditions and Effect of Delayed-Release Dimethyl Fumarate Treatment Sujata Sarda, Glenn Phillips, Julia Gaebler, Nuwan Kurukulasuriya

P4.183 Patient-Reported

Psychological Functioning in Natalizumabtreated Patients with Multiple Sclerosis in US Clinical Practice  John Foley, Kavita Nair, Judith Stephenson, Timothy Vollmer, Timothy Niecko, Sonalee Agarwal, Crystal Watson

MS and CNS Inflammatory Disease: Disability Progression P4.184

Predicting Disability in the Modern MS Cohort  Roland Henry, Esha Datta, Alyssa Zhu, Bagrat Amirbekian, Regina Schlaeger, Refujia Gomez, Rachel Kanner, Caroline Ciocca, Jeffrey Gelfand, Douglas Goodin, Ari Green, Stephen Hauser, Bruce Cree

P4.185

The Risk of Progression in MS Depends on the Features of Preceding Relapses: Application to First Generation Immunomodulating Theraphy Helen Tedeholm, Bengt Skoog, Bjorn Runmarker, Anders Odén, Oluf Andersen

P4.186

Incomplete Relapse Recovery and Sustained Disability Progression in Multiple Sclerosis in Pittsburgh Edward Gettings, Chris Hackett, Carol Schramke, Thomas Scott

P4.187

Clinical Predictors of Expanded Disability Status Scale Rank Change Over 5-Year Intervals in the MSBase Registry  Stella Hughes, Timothy Spelman, Maria Trojano, Alessandra Lugaresi, Guillermo Izquierdo, Francois Grand-Maison, Pierre Duquette, Marc Girard, Pierre Grammond, Celia OrejaGuevara, Raymond Hupperts, Cavit Boz, Roberto Bergamaschi, Giorgio Giuliani, Edite Rio, Jeannette Lechner-Scott, Vincent Van Pesch, Gerardo Iuliano, Marcela Fiol, Freek Verheul, Michael Barnett, Mark Slee, Joseph Herbert, Ilya Kister, Norbert Vella, Fraser Moore, Tatjana Petkovska-Boskova, Vahid Shaygannejad, Vilija Jokubaitis, Gavin McDonnell, Stanley Hawkins, Frank Kee, Helmut Butzkueven, Orla Gray

P4.188

Predictors of Disability Extremes in Patients with Multiple Sclerosis Treated with Interferon-beta Using the Swedish MS Registry Katharina Fink, Anna Fogdell-Hahn, Jan Hillert

P4.189

Previous Disability Has an Influence in Recovery of Multiple Sclerosis Relapses Treated with Methylprednisolone?  Cristina Ramo, Laia Grau-López, Maria Tintore-Subirana, Alex Rovira, Lluis Ramio, Luis Brieva, Albert Saiz, Carlos Nos, Antonio Cano, Olga Carmona, Ferran Torres, Jose Vicente Hervas, Xavier Montalban, Joan Costa

P4.190

Relationship Between Sustained Expanded Disability Status Scale Progression and Simultaneous Changes in Individual Functional Systems in RelapsingRemitting Multiple Sclerosis Thomas Scott, Bjorn Sperling, Ping Wang, Xiaojun You, Monica Mann

P4.191

Evaluating TMS Motor Evoked Potentials in Early Stages of Multiple Sclerosis Aid in Predicting Disability  Nilufer Kale, Gulten Ozdemir, Eda Coban, Jale Agaoglu

P4.192

Sustained Disability Improvement Associated with Reduced MRI Lesion Burden in Natalizumab-Treated Patients with Multiple Sclerosis Luca Prosperini, Floriana De Angelis, Rosanna De Angelis, Fulvia Fanelli, Carlo Pozzilli

P4.193

A Multi-Modal Neurophysiological Evaluation of Primary Progressive Multiple Sclerosis—a Cross Sectional and Longitudinal Cohort Analysis  Luke Canham, David Cottrell, Nick Kane, Jonathan Witherick, Kelly Blake, Peter Walsh

Aging, Dementia, and Cognitive and Behavioral Neurology: Early Diagnostic Markers P4.194

Normal HDL But Not the HDL from Patients with Coronary Heart Disease Prevent LDL Induced Toxicity in Cultured iCell Neurons.  Samra Vazirian

P4.195

A Predictive Model for Cognitive Impairment in Individual Patient with Diabetes Mellitus  Martin Rakusa, Matej Rakusa, Miro Cokolic

P4.196

Mild Cognitive Impairment (MCI)in Parkinson Disease (PD) and Lewy Body Disease(LBD): Who Became to Dementia?  Maria Garcia Basalo, Maria Fernandez, Carla Stefani, Waleska Berrios, Diego Bauso, Juan Ignacio Rojas, Edgardo Cristiano, Angel Golimstok

P4.197

A portable Non-Invasive Biosensor Based Approach to Actively Assess Cognitive Function in Alzheimer’s Disease (AD) and Beyond  Allan Bernstein, Terry Hess, Parham Ghorbanian, Hashem Ashrafiuon, David Devilbiss, Adam Simon

P4.198

Cognitive Impairment in Healthy Filipino Adults with MRI Nonspecific White Matter Change  Ty Alekzander Talamera, Jacqueline Dominguez, Merceditas Dizon

P4.199

Microstuctural Alteration of the Default Mode Network as a Predictor of Cognitive Impairment in Alzheimer’s Disease  Marina Weiler, Brunno de Campos, Mateus Nogueira, Tátila Lopes, Benito Damasceno, Fernando Cendes, Marcio Balthazar

P4.200

Theory of Mind: a Cognitive Marker of Conversion from Mild Cognitive Impairment to Alzheimer Disease? Noémie Moreau, Stéphane Rauzy, François Viallet, Maud Champagne-Lavau

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Wednesday April 30



First Authors stand by Posters from 7:30 a.m.–9:00 a.m.



Wednesday, April 30 P4.201

The Pituitary Adenylate Cyclase Activating Polypeptide Levels Are Associated with Pathological Features of Alzheimer’s Disease  Jiong Shi, P Han, L Baxter, W Liang, Z Tang, J Yin, T Beach, R Caselli, E Reiman

Aging, Dementia, and Cognitive and Behavioral Neurology: Frontotemporal Lobar Degeneration P4.202

Motor Neuron Dysfunction In Frontotemporal Lobar Degeneration: A Clinical and Neurophysiological Study  Chiara Cerami, Alessandra Marcone, Claudio Marangoni, Chiara Crespi, Alessandra Dodich, Nicola Canessa, Sandro Iannaccone, Zamboni Michele, Valeria Golzi, Maria Cristina Giusti, Stefano Cappa

P4.203

Do We Need a Change? Utility of Standard Cognitive Screening Instruments in Patients with Amyotrophic Lateral Sclerosis  Eileen Moran, Katya Rascovsky, Ashley Boller, Leo McCluskey, Lauren Elman, David Libon, Murray Grossman

P4.204

Cognitive Impairment (CI) in Amyotrophic Lateral Sclerosis (ALS): A Clinical Based Study  Marcelo Chaves, Maria Garcia Basalo, Mariela Bettini, Maria Fernandez, Edgardo Cristiano, Marcelo Francisco Rugiero, Angel Golimstok

P4.205

Cytokine Gene Expression in Peripheral Cells from Patients with Frontotemporal Lobar Degeneration Due to GRN and C9ORF72 Mutation Daniela Galimberti, Chiara Fenoglio, Rossana Bonsi, Maria Serpente, Chiara Villa, Sara Cioffi, Cinzia Barone, Andrea Arighi, Laura Ghezzi, Giorgio Fumagalli, Elio Scarpini

P4.206

TDP-43 in Alzheimer’s Disease Is Not Associated with Parkinsonian Features or Clinical FTD  Youngsin Jung, Dennis Dickson, Melissa Murray, David Knopman, Bradley Boeve, Ronald Petersen, Keith Josephs

P4.207

The Clock Drawing Test in Behavioral Variant Frontotemporal Dementia Versus Alzheimer’s Disease  Robin Barrows, Joseph Barsuglia, Donald Eknoyan, Valeriy Sabodash, Mario Mendez

P4.208

Clinician Versus Family Caregiver Ratings of Behavioral Variant Frontotemporal Dementia Joseph Barsuglia, Hemali Panchal, Aditi Joshi, Robin Barrows, Michelle Mather, Elvira Jimenez, Mario Mendez

7:30 a.m.–11:00 a.m.

Cerebrovascular Disease and Interventional Neurology: Acute Stroke Endovascular

Cerebrovascular Disease and Interventional Neurology: Acute Stroke Thrombolysis

P4.209

P4.219

“Heparin-Less” Protocol for Endovascular Treatment of Acute Ischemic Stroke  Asif Khan, Ameer Hassan, Taqi Zafar, Ahmed Malik, Malik Adil, Muhammad Suri, Adnan Qureshi

P4.210

Interim Recanalization in Acute Ischemic Stroke Patients Selected for Endovascular Treatment by CT Angiography  Mushtaq Qureshi, Farhan Siddiq, Daraspreet Kainth, Adnan Qureshi

P4.211

Troponin Elevation in Intraarterial Stroke Intervention  Abhay Kumar, Sonal Mehta, Aws Alawi, Amanda Michael

P4.212

Downstream Clot Fragment Migration During Endovascular Clot Extraction Adversely Affects Clinical Outcome  James Frey, Carol Darbonne, Joni Clark, Allison Tucker, Christina Chapple

P4.213

Intervention Stroke Assessment Scale for Eligibility in Endovascular Therapy (ISASET)  Dababneh Haitham, Asif Bashir, Mohammed Hussain, Sara Misthal, Mohammad Moussavi, Jawad Kirmani

P4.214

“No Turn Back Approach” to Reduce Treatment Time for Endovascular Treatment of Acute Ischemic Stroke  Hossam Egila, Malik Adil, Harris Siddiqi, Nidaullah Mian, Ameer Hassan, Jefferson Miley, Gustavo Rodriguez, Muhammad Suri, Adnan Qureshi

P4.215

Thrombus Density Predicts Successful Recanalization with StentRetriever Thrombectomy in Acute Ischemic Stroke  Maxim Mokin, Simon Morr, Sabareesh Natarajan, Adnan Siddiqui, Elad Levy

P4.216

Optical Bedside Monitoring of Cerebral Blood Flow in Acute Ischemic Stroke Patients During Head of Bed Manipulation  Christopher Favilla, Rickson Mesquita, Michael Mullen, Turgut Durduran, Meeri Kim, David Minkoff, Scott Kasner, Greenberg Joel, Arjun Yodh, John Detre

P4.217

Endovascular Treatment of Acute Basilar Artery Occlusion Roman Herzig, Tomas Dornak, David Skoloudik, Daniel Sanak, Martin Kuliha, Martin Roubec, Roman Havlicek, Lenka Hajdukova, Martin Kocher, Vaclav Prochazka, Jiri Lacman, Frantisek Charvat, Michal Kral, Tomas Veverka, Jana Zapletalova

P4.218

Intra-procedural Heparin Increases Mortality and Reduces Rates of Favorable Outcome in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment  Vishal Jani, Avean Saed, Tanya Mohindroo, Mushtaq Qureshi, Syed Hussain, Fareed Suri, Adnan Qureshi

Safety of tPA + Transcranial Emission of Low-energy Lasers for Acute Stroke Recovery—Results Thomas Hemmen, Rema Raman, Souvik Sen, Madeleine Geraghty, Karen Rapp, Steven Richeri, Brett Meyer, Justin Zivin, Christopher Fanale

P4.220

Thrombolytic Outcomes for Acute Ischemic Stroke in Patients with Primary Brain Tumors in the United States  Santosh Murthy, Yogesh Moradiya, Shreyansh Shah, Aditi Shastri, Eric Bershad, Jose Suarez

P4.221

Balancing Rapid Treatment Goals with Thorough Laboratory Evaluation in Alteplase Candidates: A Review of a Stroke Center’s Current Practices and Outcomes  Stacy Smith, John Volpi

P4.222

Serum Albumin Is Associated with Cerebral Hemorrhage in PostIntravenous Thrombolytic Therapy for Acute Stroke: A Retrospective Chart Review  Haris Kamal, Ping Li, Kelly Smith, Ghulam Mustafa, Robert Sawyer, Marilou Ching, Bijal Mehta

P4.223

Thrombolytic Treatment for Acute Ischemic Stroke Patients with History of Migraine Headaches Ahmed Malik, Malik Adil, Saqib Chaudhry, Adnan Qureshi

P4.224

Intravenous Thrombolysis for Acute Ischemic Stroke in the 3- to 4·5-hour Window—the Malabar Experience  Karadan Ummer, K. Salam, Mohan Noone, Pradeep Kumar

P4.225

The effect of statin pretreatment and Serum Lipid Values on Hemorragic Conversion After rt-PA for Acute Ischemic Stroke  Ayaz Khawaja, Michael Lyerly, Gyanendra Kumar, Kara Sands, Reza Bavarsad Shahripour, Andrei Alexandrov

P4.226

Can CT Perfusion Identify Patients Unlikely to Show Improvement Following Intravenous Thrombolysis?  Dushyant Damania, Nancy Kung, George Koch, Minal Jain, Anunaya Jain, Babak Jahromi

Life Threatening Intracranial Hemorrhage as a Consequence of Dobutamine Stress Echocardiography: A Case Report  Adithya Sivaraju, Vineet Punia, Machteld Hillen

P4.231

Can Transthoracic Echocardiography be Useful Detecting Patent Foramen Ovale in Stroke? The of Valsalva Maneuver  Ana Iglesias Mohedano, Fernando Diaz Otero, Andres García Pastor, Raquel Yotti, PIlar Vazquez Alen, Raul Dominguez Rubio, Fernando Romero Delgado, Adriana Muñoz González, Pilar Sobrino García, Yolanda Fernández Bullido, Antonio Villanueva Osorio, Antonio Gil-Nunez

P4.232

Cardiac Autonomic Neuropathy, Screening, Staging and Follow-Up, a Five Year Study from a General Hospital  Lalitha Rajanala, Sundarachary Nagarjunakonda, Veeramma Doctor

P4.233

Cardiac Valve Strands in Ischemic Stroke: Strand Effects and Outcomes of Medical or Surgical Intervention  Jennifer Chu, Roderic Fabian

P4.234

Review of Cardiac Abnormalities with Hypercoagulable Testing in Ischemic Stroke Patients  Nicolaas Anderson, Akshay Shah, Kendra Drake, Maria Proytcheva, Bruce Coull

P4.235

Systemic Inflammation Exacerbates Stroke in Patients with Left Ventricular Assist Device  Ryo Ohtomo, Atsushi Iwata, Osamu Kinoshita, Jun Shimizu, Minoru Ono, Shoji Tsuji

P4.236

Transcranial Doppler to Assess Cerebral Blood Flow in Patients on Extra Corporeal Membrane Oxygenation  Sanam Baghshomali, Patrick Reynolds, Aarti Sarwal

Cerebrovascular Disease and Interventional Neurology: Endovascular Neurology P4.237

Venous Flow Stagnation in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment  Mushtaq Qureshi, Daraspreet Kainth, Adeel Memon, Adnan Qureshi

P4.227

P4.238

Cerebrovascular Disease and Interventional Neurology: Cardiac

P4.239

Vitreous Hemorrhage as a Complication of IV-tPA Therapy in a Patient with Acute Stroke  Laxmi Shah, Thierry Verstraeten, David Wright, Sandeep Rana

P4.228

Utility of Pelvic MRV in Evaluation of Patients with Cryptogenic Stroke and PFO  Marcey Osgood, Elizabeth Budman, Nils Henninger

P4.229

Effect of Patent Foramen Ovale (PFO) Endovascular Closure on Stroke Quality of Life  Feeney-Heinzelmann K, MingMing Ning, W Deng, T Wickham, I Inglessis, Eng Lo, I Palacios, Ferdinando Buonanno

86

P4.230

2O14 Scientific Abstract Listing and Annual Meeting Information

Functional Status and 5-year Survival Among Elderly Americans: Implications for Patient Selection for Surgical and Endovascular Procedures  Ahmed Malik, Malik Adil, Adnan Qureshi Is Hemoglobin A1c (HbA1C) Level an Independent Predictor of Adverse Outcomes in Patients with Acute Ischemic Stroke Undergoing Endovascular Treatment?  Mohammad Afzal, Saqib Chaudry, Taqi Zafar, Ali Saeed, Mohammad Owais, Malik Adil, Vikram Jadhav, Ameer Hassan, Syed Hussain, Adnan Qureshi

Poster Session IV

P4.240

Motor Component of National Institute of Health Stroke Scale Effect on Functional Outcome and Mortality at Discharge in Patient Receiving Endovascular Therapy Sara Misthal, Dababneh Haitham, Asif Bashir, Mohammed Hussain, Mohammad Moussavi, Jawad Kirmani

P4.241

Intravenous Thrombolysis Versus Endovascular Treatment for Acute Ischemic Stroke: A Meta-Analysis of Randomized Controlled Trials Nidaullah Mian, Farhan Siddiq, Mushtaq Qureshi, Malik Adil, Asif Khan, Muhammad Suri, Adnan Qureshi

P4.253

Case of Occipital Epilepsia Partialis Continua Presenting as Status Migrainosus: Clinical, EEG and Brain MRI Findings  Weiwei Dai, Madeleine GriggDamberger

P4.254

Efficacy of Lacosamide in Epilepsia Partialis Continua Devanshi Jadhav, Daniel Birnbaum, Kathleen Burger, Mohamad Koubeissi

P4.255

Epilepsia Partialis Continua Secondary to Ischemic Stroke, Responsive to the Combination of Levetiracetam and Lacosamide  Rebecca Thompson, Najib Murr, Pierre Fayad

P4.242

Epilepsy and Clinical Neurophysiology (EEG): Non-Epileptic Seizures and SUDEP

P4.243

P4.256

The Future Role of Interventional Neurology—A Survery of Neurology Department Program Directors and Clerkship Directors.  John Leschke An Updated CostEffectiveness Analysis (CEA) of r-tPA for Acute Ischemic Stroke (AIS) Treated Within 3 Hours of Symptom Onset Denise Boudreau, Gregory Guzauskas, Darren Tayama, Susan Fagan, David Veenstra

P4.244

The Future Role of Interventional Neurology—a Survey of Neurology Department Chairmen. John Leschke

P4.245

Performance Metrics for The Interventional Treatment of Acute Ischemic Stroke; Results from a Comprehensive Stroke Center  Ali Sultan-Qurraie, Adam de Havenon, Kyra Becker, Deepak Sharma, Danial Hallam, Basavaraj Ghodke, Louis Kim, David Tirschwell

Epilepsy and Clinical Neurophysiology (EEG): Status Epilepticus P4.246 WITHDRAWN P4.247 Non-convulsive

Status Epilepticus in Comatose Patients.  Alejandro Thomson, Analia Calle, Agustina Tamargo, Maria Gonzalez Toledo, Fatima Pagani Cassara, Diego Nadile, Vladimiro Sinay, Alfredo Thomson

P4.248

Early Identification of Status Epilepticus Etiology with a Simple Clinical Tool  Vincent Alvarez, Jong Lee, M. Westover, Andrea Rossetti

P4.249

Intravenous Versus Non-intravenous Benzodiazepines for the Treatment of Status Epilepticus: A Systematic Review and MetaAnalysis  Ahmad Abulaban, Abdussalam Alshehri, Suleiman Kojan, Rakan Bokhari

P4.250 Benzodiazepine

Administration for Seizure Emergencies: A Review  Sheryl Haut, Syndi Seinfeld, John Pellock

P4.251

Diazepam Useful in ESES Treatment  Mirret El-Hagrassy, Chulaka Gunasekara, Yaman Eksioglu

P4.252

Temperature Modulation for Refractory Status Epilepticus Barry Czeisler, Sohil Manvar, Gian Marco De Marchis, Deborah Pugin, Andres Fernandez, Brandon Foreman, J. Michael Schmidt, Neeraj Badjatia, Sachin Agarwal, Stephan Mayer, Jan Claassen

A Case Series Exploration of a Possible Relationship Between Non-Epileptic Behavioral Spells and Migraine  Andrew Tseng, Jeffrey Staab, Ivan Garza, Gregory Cascino

P4.257

Relevance of Psychogenic and Epileptic Seizures Coexisting in an Epilepsy Monitoring Unit Population  Alan Krumholz, Diane Thomas

P4.258

Role of Placebo Induction in Epilepsy Monitoring Unit  Ahmed Yassin, Todd Masel

P4.259

Diagnostic Yield of Prolonged Electroencephalogram In Pediatric Syncope Patients  Cimy Jacob, Alice Daniel, Josiane LaJoie

P4.260

The Spectrum of Ictal Asystole: A Case Series  David Harris, Maromi Nei

P4.261

Age-specific Periictal Electroclinical Features of Generalized Tonic-clonic Seizures and Potential Risk of Sudden Unexpected Death in Epilepsy (SUDEP).  Gurmeen Kaur, Joel Freitas, Samden Lhatoo, Guadalupe FernandezBacaVaca, Curtis Tatsouko

P4.267

Lamotrigine, a Narrow Therapeutic Index Drug or Not? Wendy Cai, Tricia Ting, James Polli, Michel Berg, Michael Privetera, Wenlei Jiang

P4.268

Psychogenic Non-Epileptic Spells: Analysis of Clinical Perspectives and Practice  Amy Hessler, Barbara Slevin, Malachy Bishop, Amelia Anderson

P4.269

Pharmaceutical Quality Assessment of Generic Lamotrigine Immediate Release (IR) Tablets  Kunyi Wu, Daniel Peng, Wenlei Jiang

P4.270

The Effect of an Educational Intervention on Compliance with AAN Guidelines for Return Epilepsy Visits: A Quality Improvement Project  Gary Nelson, Lynne Kerr, Francis Filloux

P4.271

David Versus Goliath: Two Competing US Trials of 3,4-Diaminopyridine (3,4-DAP) in Lambert-Eaton Myasthenic Syndrome (LEMS)  Donald Sanders

P4.272

Development and Implementation of a Quality Improvement Strategy for Obtaining Muscle Biopsies Utilizing DMAIC Methodology Charles Kassardjian, Michelle Williamson, Dorothy Van Buskirk, Floranne Ernste, Andrea Leep Hunderfund

P4.273

Routine Versus Electronic Data Collection in Multiple Sclerosis Patients  Wael Richeh, Jesus Lovera, Amparo Gutierrez, Nicole VillemarettePittman, Raisa Martinez

P4.274

Cross Validation of Local Labs to Eliminate Reference Lab Testing for Varicella Zoster ELISA: A Model for Reducing Send Out Labs to Improve Care and Lower Cost.  Alexander Hartmann

P4.275

Does Effective Communication Between Patients and Ordering Physicians Improve Patient Satisfaction and the Quality of Electrodiagnostic Studies?  Divpreet Kaur, Yadira VelazquezRodriguez, Aiesha Ahmed

P4.262

Practice, Policy, and Ethics: Training and Common Practices in Neurology

P4.263

P4.276

Epilepsy, Syncope, and SUDEP, a Small Case Series  Camilo Garcia-Gracia, Nancy Rosales, Rachana Gandhi Efficacy and Safety of Vigabatrin in 90 Pediatric and Adult Patients with Epilepsy  Dimitrios Arkilo, Caitlin Narusiewicz, Janet Branson, Jennifer Brunn, Carol Hoskin, Patricia Penovich, Michael Frost

P4.264

Lacosamide Retention Rates in Pediatric Epilepsy  Emily Robbins, Sudha Kessler, Julia Cohen

P4.265

Prescribing Trends of Antiepileptic Drugs for Epilepsy Within the Veterans Health Administration  Tung Tran, Rizwana Rehman, Aatif Husain

Practice, Policy, and Ethics: Epilepsy, Neuromuscular, and Neuroimmunology P4.266

Improving Patient Satisfaction The Neurology Service  Sonia Krish, Nicole Harrison, Enedra Allen-Mcbride, Paul Schulz



Unplanned Transfers to a Neurological Intensive Care Unit  Carl Gold, Stephan Mayer, Laura Lennihan, Joshua Willey

P4.277

Who Is Your Neurologist?: Measuring the Efficacy of a Resident Run Continuity Clinic  Reshma Gokaldas, Maheep Singh, Robert Fekete

P4.278

Improving Patient Hand-Offs in a University Neurology Residency Program  Catherine Porter, Lynn Chouhfeh, Alyssa Fiddler, Salomi Salins, Novreen Shahdad, Nicholas Silvestri

P4.279

Standardized Patient Handoff Improves Resident Confidence and Patient Safety  Justin Jordan, Steven Vernino

P4.280

Timeliness of Neurology Consultations in the Emergency Department: A Quality Evaluation  Samantha Holden, Steven Lewis

P4.281

Lumbar Puncture: a Dying Procedure Among Neurologists?  Elizabeth Flaherty, Aimee Szewka

P4.282

Physician Compensation and Patient Satisfaction: Unintended Consequences of Policy Misalignment  Jack Riggs, Kevin Riggs

P4.283

Analysis of Inter-Provider Conflicts in Healthcare  Mark Stecker, Mona Stecker

Practice, Policy, and Ethics: Stroke, Critical Care, and Other P4.284

Timely Initiation of Therapeutic Hypothermia Following Cardiac Arrest: A Resident-Driven Quality Improvement Project  Laura Rosow, S. Josephson

P4.285

Re-evaluating Brain Death: The Potential for Treatment and Recovery After Brain Injury  Philip Defina, Christine Zakrzewski, Charles Prestigiacomo, Calixto Machado, Peter Bernad, James Halper, Jonathan Fellus

P4.286

Are AHA/ASA Stroke Guidelines Evident Enough? Swaroop Pawar, Andrea Boan, M. Kamran Athar, Tanya Turan

P4.287

Improving Secondary Stroke Prevention Following Acute Ischemic Stroke: A Practice Improvement Project.  Andrea Harriott

P4.288

Natural Language Processing Method Accurately Classifies and Extracts Unstructed Data from Stroke Admission and Progress Notes  Daniel Franc

P4.289

What’s the True Definition of an Adverse Event?  Raghav Govindarajan

P4.290

Improving Assessment and Documentation of Pain Management at University of Florida—Jacksonville. Denys Shapovalov, Nader Antonios

P4.291

Quality Improvement Project on Hand Washing at Memorial Hermann Hospital  Jitesh Kar, Kristin Brown, Terry Walker, Janete Sheiner, Janelle Headley, Allison Murphy, Stephanie Cooper, Enedra Allen-McBride, Miriam Morales, Paul Schulz

Global Health and Infection P4.292

Helping Haiti: Addressing the Burden of Neurologic Disease Veronica Santini, Anthony Alessi, Elaine Jones, Mill Etienne, Anna Hohler

P4.293

Cognitive and Neurodegenerative Disorders in Adults in Africa: A Systematic Review Hannah McLane, Tarun Singhal, Joel Negin, Neelum Aggarwal, Anhar Hassan, Farrah Mateen

P4.294

Epidemiology and Etiology of Acute Infectious Neurologic Disease (AIND) in Singapore  Kevin Tan, Monica Chan, Nadika Wijesoma, Peng Soon Ng, Ambihai Sivalingam, Tianrong Yeo, Yee-Sin Leo, October Sessions, Eng-Eong Ooi, Duane Gubler, Umapathi Thirunagnam, James Sejvar

Fast, Easy Registration Online  ·  AAN.com/view/AM14

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Wednesday April 30



First Authors stand by Posters from 7:30 a.m.–9:00 a.m.



Wednesday, April 30 P4.295 NeurologicManifestations

of Neglected Tropical Diseases Pooja Raibagkar, Aaron Berkowitz, Bobbi Pritt, E. Tessa Headley-Whyte, Farrah Mateen

P4.296

Aspirin for Acute Stroke of Undetermined Etiology in Resource-limited Settings: A Decision Analysis Aaron Berkowitz, M. Westover, Matt Bianchi, Sherry Chou

P4.297

Risk Factors for Cerebral Palsy in Botswana  David Bearden, Baphaleng Monokwane, Dennis Kolson, Greg Bisson

P4.298

Variations in Brain Death Declaration: A Worldwide Survey Sarah Wahlster, Eelco Wijdicks, Pratik Patel, David Greer, Claude Hemphill, Farrah Mateen

P4.299

Neurology International Residents Videoconference and Exchange (NIRVE)  Mary Jane Lim Fat, Manav Vyas, Jenny Tsai, Mark Kinach, Tim Patterson, Morris Freedman

P4.300

International Affiliation as a Tool to Improve the Quality and Safety of Inpatient Care. Experience Neurological Center, the American British Cowdray Medical Center. Mexico City Aurelio Mendez, Roberto Alfonso De Leo-Vargas, Alejandro Alfonso-Díaz, Guillermo ReyesCaballero, Marco Alegria, Patricia ConchaHein, Claudia Cabrera

P4.301

International Electives in Neurology Training: A Survey of U.S. and Canadian Program Directors Jennifer Lyons, Mary Coleman, John Engstrom, Farrah Mateen

P4.307

Central and Peripheral Markers of Neurodegeneration and Monocyte Activation in HIV-Associated Neurocognitive Disorders Jennifer McGuire, Alexander Gill, Steven Douglas, Dennis Kolson

P4.308

The Effects of a Novel Interferon Inhibitor in a Model of HIV Encephalitis  William Tyor, Cari Lessing, Ramzi Shawahna, Jennifer Ward, Leonard Maroun

P4.309

Biochemical Evidence of Neuronal Injury in HIV Patients with Normal Neurocognitive Function Defines Pre-symptomatic Stage  Gloria Von Geldern, Caroline Anderson, Ned Sacktor, Justin McArthur, Avindra Nath

P4.310

Establishment of a Multi-disciplinary Platform for HIVinfected Patients with Neurological Complications  Renaud Du Pasquier, Samanta Simioni, Deolinda Alves, Reto Meuli, Giorgio Maccaferri, Alexandre Berney, Matthias Cavassini

P4.311

Clinical and Bacteriological Features of Central Nervous System Tuberculosis in Patients with HIV-Infection in Siberian Region of Russia  Yury Bykov, Tatiana Filippova, Olga Novitskaya

Viral Encephalitis and Progressive Multifocal Leukoencephalopathy P4.312

NeuroAIDS

Analysis of YouTube as a Source of Information for West Nile Virus Infection  Anshudha Sawhney, Divyanshu Dubey, Amod Amritphale, Nupur Amritphale

P4.302

P4.313

Risk Factors for Epilepsy in Children with HIV/AIDS in Botswana David Bearden, Greg Bisson, Dennis Kolson, Andrew Steenhoff, Sudha Kessler, Dennis Dlugos

P4.303

Stroke in Children with Human Immunodeficiency Virus in Botswana: A Report of Six Cases  Esha Khurana, David Bearden

P4.304

The Risk of Large-Artery Atherosclerotic Stroke Is Proportionally Greater than Cardioembolic Stroke in HIV-Infected Individuals Compared to HIVUninfected Controls  Felicia Chow, Richard Price, Priscilla Hsue, Anthony Kim

P4.305

Neurological Disease Presentations in an Out-patient Setting in the Effective Antiretroviral Therapy Era  Samitha Fernando, Matthew Poynton, Alex Everitt, Alan Winston

P4.306

Deficiency of Brain Heme Oxygenase-1 in HIV-Infected Individuals: Potential Target for Adjunctive Therapy  Alexander Gill, Suren Ambegaokar, Colleen Kovacsics, Stephanie Cross, Benjamin Gelman, Dennis Kolson

88

HSV 2 Encephalitis Presenting as Episodic Receptive Aphasia Mohamad Ezzeldin, Ahmed Yassin, Merry Chen

P4.314

Diagnostic Delay in a Case of HSV Encephalitis  Janhavi Modak, Kevin McMahon, Avinash Prasad

P4.315

HHV6 Encephalitis Complicating Post Stem Cell Transplantation Course: A Case Series of Five Leukemic Patients  Ahmed Yassin, Tummala Sudhakar

P4.316

Eastern Equine Encephalitis in a Patient Treated with Rituximab: Clinical Presentation and Histopathology Shibani Mukerji, Pedro Ciarlini, Sandro Santagata, Umberto De Girolami, Sashank Prasad

P4.317

Magnetic Resonance Imaging and Electroencephalograhic Characteristics in Two Cases of Fatal Eastern Equine Encephalitis (EEE)  Mohamed-Ali Babi, Angela Applebee, Robert Shapiro, Todd Raleigh, Joseph McSherry

P4.318

Thrombocytopenia as a Prognostic Factor in Encephalitis Anthony Asemota, Kiran Thakur, Romergryko Geocadin, Arun Venkatesan

7:30 a.m.–11:00 a.m. P4.319

Progressive Multifocal Leukoencephalopathy Associated with Ofatumumab Presenting as Alexia Without Agraphia: A Case Report  Jose Avila, Jennifer Han, Islam Zaydan

P4.320

Non-HIV PML: A Case of PML in an Immunocompetent Patient with a Retrospective Review on Non-HIV PML Risk Factors  Barbara Graves, William Bambach, Rebecca Hosey, Jonathan Hosey

P4.321

A Unique Case of Progressive Multifocal Leukoencephalopathy in a Patient with Chronic Lymphocytic Leukemia Who Has Never Received Chemotherapy  Jared Noroozi, Sonia Lal, Brij Ahluwalia-Singh, Ramandeep Sahni

Child Neurology and Developmental Neurology IV P4.322

Diagnostic Yield of Pediatric EMG in Myopathic Disorders Partha Ghosh, Eric Sorenson

P4.323

Can You Fine Tune the Ketogenic Diet  Jessica Selter, Zahava Turner, Sarah Doerrer, Eric Kossoff

P4.324

Occipital Headaches and Neuroimaging in Children  Joshua Bear, Amy Gelfand, Peter Goadsby, Nancy Bass

P4.325

Infantile Cerebral Arterial Calcification  Jennifer Chu, Shannon DiCarlo, Robert Zeller

P4.326

Efficacy and Tolerability of Intravenous Lacosamide in Children Less Than 12 Years of Age  Dimitrios Arkilo, Mary Gustafson, Jason Doescher, Frank Ritter

P4.327

Methylphenidate Exerts DoseDependent Effects on Glutamate Receptors and Cognitive Behaviors  Jia Cheng, Zhe Xiong, Lara Duffney, Sihang Liu, Zhen Yan

P4.328

Neurologic Injury in Isolated Sulfite Oxidase Deficiency  Thomas Bosley, Ibrahim Alorainy, Darren Oystreck, Khaled Abu-Amero, Mustafa Salih

P4.329

The Epidemiology of Pediatric Open Brain Surgery in the United States.  Shalini Selvarajah, Nicholas Carchedi, Edward Hammond, Marcelo Cerullo, Anthony Asemota, Joseph Canner, Eric Schneider

P4.330

Hemodynamic Changes Associated with Interictal Epileptiform Activities Using Simultaneous Video Electro-encephalography (EEG)/Near Infrared Spectroscopy (NIRS) in Patient Self Control Study  Kumar Sannagowdara

P4.331

Management of Choreoathetosis Secondary to Sequential Herpes Simplex Virus Type-1 Infection and Anti-NMDA Receptor Encephalitis in a 6-Month-Old Girl  Yefim YushvayevCavalier, Charles Nichter, Adolfo Ramirez Zamora

2O14 Scientific Abstract Listing and Annual Meeting Information

P4.332

Eight-year Latency to Diagnosis in an Adolescent with Bilateral Basal Ganglia Germinomas Mimicking a Neurodegenerative Condition Anna Nordvig, Alexis Dallara, Arthur Mandel, Toni Pearson

P4.333

3D Kinematic Gait Analysis in Mucopolysaccharidoses  Igor Nestrasil, Christopher Fuller, Alia Ahmed, Elsa Shapiro, John Anderson

P4.334

Correlation Between MRI Findings of Mesial Temporal Sclerosis and Histopathological Findings  Judy Li, Steve Chung

P4.335

Familial Episodic Encephalopathy, Dysarthria, and Paralysis Is Associated with a Dominantly Inherited Mutation in ATP1A3  Gyula Acsadi, Richard Young, Tara Newcomb, Benjamin Nelson, Louis Viollet, Kathryn Swoboda

P4.336

Genetic Animal Models of Autism Based on Shank/ Mutation Molecules to Potential Therapeutics Craig Powell

P4.337

Knockout of p75NTR in Cerebellar Purkinje Cells Results in an Autism-like Murine Phenotype Nina Schor, Deborah Cory-Slechta, Louis Lotta, Katherine Conrad

P4.338

Exonic Deletion of SLC9A9 in Autism with Epilepsy  Meeta Wagle, Jimmy Holder

P4.339

High-Functioning Autistic Children Have Abnormal Stapedial Reflexes  Richard Lukose, Randy Kulesza, Kevin Brown, Barber Carol

P4.340

Delayed Low Level Visual Processing in Infants with Tuberous Sclerosis Complex (TSC)  Pilar Pichon, Jordan Ko, Charles Nelson III, Shafali Jeste

P4.341

Mean EEG Coherence in Infants at Risk for Autism Spectrum Disorder  April Levin, Marc Shi, Helen Tager-Flusberg, Charles Nelson

CNS and Disease Mechanisms in Humans and Animal Models P4.342

B Cells from Blood of Patients with Relapsing-Remitting Multiple Sclerosis Induce Apoptosis in Neurons In Vitro  Robert Lisak, Liljana Nedelkoska, Hanane Touil, Joyce Benjamins, Beverly Bealmear, Riu Li, Hetoum Misirliyan, Amit Bar-Or

Plenary Session

Current as of 2/13/2014 

Contemporary Clinical Issues Plenary Session  ighlights issues most critical to practicing neurologists, including H abstracts related to new therapeutic developments, clinical applications of basic and translational research, and innovative technical developments.

9:00 a.m.–12:00 p.m. Moderator: Lisa M. DeAngelis, MD, FAAN

Chair, Science Committee

Comparison of Thrombolytic Treatment for Acute Ischemic Stroke Pre- and PostTelemedicine Implementation in the Spoke Hospital Setting 

William K. Mountford, PhD Premier Research Services, Wilmington, NC



Discussant: Lee H. Schwamm, MD Massachusetts General Hospital, Boston, MA

Epigenetic Therapy for Friedreich’s Ataxia: A Phase I Clinical Trial 

David R. Jacoby, MD, PhD BioMarin Pharmaceutical Inc., Novato, CA



Discussant: Tetsuo Ashizawa, MD, FAAN University of Florida, Gainesville, FL

Clinical Profile of the Orexin Receptor Antagonist Suvorexant for the Treatment of Insomnia in Phase-3 Clinical Trials 

William Herring, MD, PhD Merck Research Laboratories, North Wales, PA

David B. Goldstein, PhD Duke University, Durham, NC

Direct to Consumer Genetic Testing

Discussant: Phyllis C. Zee, MD, PhD Northwestern University Medical School, Chicago, IL

Jonathan Stone, MB, ChB, FRCP, PhD Western General Hospital, Edinburgh, United Kingdom

Functional (Psychogenic) Disorders in Neurology

Kenneth L. Marek, MD Institute for Neurodegenerative Disorders, New Haven, CT

Parkinson’s Disease Progression Marker Initiative: Developing a Translational Toolbox for PD Progression

For Full Abstracts and Bios for Plenary Speakers Visit AAN.com/view/SearchAM

Fast, Easy Registration Online  ·  AAN.com/view/AM14

89



Wednesday, April 30 S24 Diet and Hormonal Influences in Multiple Sclerosis 2:00 p.m. S24.001 Increased Archaea Species and Changes with Therapy in Gut Microbiome of Multiple Sclerosis Subjects   Sushrut Jhangi, Roopali Gandhi, Bonnie Glanz, Sandra Cook, Parham Nejad, Doyle Ward, Ning Li, Georg Gerber, Lynn Bry, Howard Weiner 2:15 p.m. S24.002 Role of Melatonin in MS Pathogenesis   Mauricio Farez, Santiago Mendez Huergo, Iván Mascanfroni, Gabriel Rabinovich, Francisco Quintana, Jorge Correale 2:30 p.m. S24.003 Investigation of Sex Differences in the Association Between Multiple Sclerosis Disease Severity and Hormonal Markers of Vitamin D, Obesity, and Testosterone.   Riley Bove, Alexander Musallam, Brian Healy, Pejvak Soltany, Pia Kivisakk, Bonnie Glanz, Philip De Jager, Karen Miller, Tanuja Chitnis 2:45 p.m. S24.004 Body Mass Index and Multiple Sclerosis Risk. The Role of Leptin   Jorge Correale, María Eugenia Balbuena Aguirre, Mauricio Farez 3:00 p.m. S24.005 Differential Effects of Vitamin D in GA- Versus IFN-Treated MS Patients   Dalia Rotstein, Brian Healy, Muhammad Taimur Malik, Robert Carruthers, Alexander Musallam, Pia Kivisakk, Bonnie Glanz, Tanuja Chitnis 3:15 p.m. S24.006 Delayed−Release Dimethyl Fumarate and Pregnancy: Preclinical Studies and Pregnancy Outcomes Reported During the Clinical Development Program   Ralf Gold, J. Theodore Phillips, Eva Havrdova, Amit Bar-Or, Ludwig Kappos, Janet Clarke, Huixing Yuan, Mark Novas, Jie Li, Marianne Sweetser, Nuwan Kurukulasuriya, Vissia Viglietta, Robert Fox 3:30 p.m. S24.007 Aromatic-Turmerone Induces Neural Stem Cell Proliferation In Vitro and In Vivo   Michael Schroeter, Joerg Hucklenbroich, Klein Rebecca, Bernd Neumaier, Rudolf Graf, Gereon Fink, Maria Rueger

S25 Cerebrovascular Disease and Interventional Neurology: Hemorrhage, Aneurysms, and Vascular Malformations 2:00 p.m. S25.001 Clinical Outcomes of Aneurysmal Subarachnoid Hemorrhage with Cocaine Use in the United States   Santosh Murthy, Shreyansh Shah, Yogesh Moradiya, Aditi Shastri, Stelios Smirnakis 2:15 p.m. S25.002 CSF Diversion in Aneurysmal Subarachnoid Hemorrhage: How Low Should We Go?   Jennifer Fugate, Alejandro Rabinstein, Eelco Wijdicks, William Freeman, Giuseppe Lanzino 2:30 p.m. S25.003 The SEDAN Score and the Risk of Intracerebral Hemorrhage in Monocenter-Study   Toralf Brüning, Mohamed Al-Khaled 2:45 p.m. S25.004 Validation of the ICH Score in Hyperacute Intracerebral Hemorrhage   Sebina Bulic, Nerses Sanossian, Sidney Starkman, David Liebeskind, Pablo Villablanca, Scott Hamilton, Robin Conwit, Jeffrey Saver

S26 Biomarkers in Neuromuscular Diseases 2:00 p.m. S26.001 Quantitative Muscle Ultrasound: Comparison of Backscatter Versus Grayscale Methods in Duchenne Muscular Dystrophy Patients and Healthy Controls   Irina Shklyar, Tom Geisbush, Aleksandar Mijailovic, Amy Pasternak, Nicole Visyak, Heather Szelag, Jim Wu, Basil Darras, Seward Rutkove, Craig Zaidman 2:15 p.m. S26.002 Basal Ganglia Involvement in Amyotrophic Lateral Sclerosis   Peter Bede, Marwa Elamin, Susan Byrne, Russel McLaughlin, Kevin Kenna, Alice Vajda, Niall Pender, Daniel Bradley, Orla Hardiman 2:30 p.m. S26.003 Impaired Cortico-Ponto-Cerebellar Networks Underlie Pseudobulbar Affect In Motor Neuron Disorders   Mary Kay Floeter, Rohan Katipally, Meredith Kim, Olivia Schanz, Stephen Matthew, Laura Danielian, Tianxia Wu, Edward Huey, Avner Meoded

3:00 p.m. S25.005 Vitamin C Depletion Is Spontaneous Intracerebral Hemorrhage Risk Factor.   Stéphane Vannier, Ronzière Thomas, Ferré Jean-christophe, Jean Francois Pinel, Marc Verin

2:45 p.m. S26.004 Pre-symptomatic Loss of Cerebral White Matter Integrity in Those at Genetic Risk of Amyotrophic Lateral Sclerosis   Martin Turner, Nicola Filippini, Varan Govind, Peter Andersen, Christine Stanislaw, Eliana Reyes, Sumaira Hussain, Joanne Wuu, Michael Benatar

3:15 p.m. S25.006 Spinal Cord Cavernous Malformations; 62-patient Retrospective Review to Define Disease Natural History   Lindsy Williams, Kelly Flemming, Robert Brown

3:00 p.m. S26.005 Profiling of miRNAs in Cerebrospinal Fluid from Patients with Amyotrophic Lateral Sclerosis   Akira Machida, Takuya Ohkubo, Atsunobu Tsunoda, Hidenori Matsuo, Yokota Takanori, Hidehiro Mizusawa

3:30 p.m. S25.007 Effect of Hyperosmolar Therapy on Outcome Following Spontaneous Intracerebral Hemorrhage: The ERICH Study   Manan Shah, Jennifer Rasmussen, Lee Birnbaum, Charles Moomaw, Padmini Sekar, Jennifer Osborne, Esther Nanez, Anastasia Vashkevich, Daniel Woo

3:15 p.m. S26.006 Diagnostic Utility of p62 Immunohistochemistry for Differentiating s-IBM from PM   Chiseko Ikenaga, Jun Shimizu, Hida Ayumi, Shoji Tsuji 3:30 p.m. S26.007 Clinical Patterns in NT5C1A Antibody Positive Sporadic Inclusion Body Myositis Patients Compared to Seronegative Patients   Namita Goyal, Farzin Pedouim, Usman Alam, Sameen Enam, Farah Mozaffar, Tahseen Mozaffar

2:00 p.m.–3:45 p.m. S27 Dystonia, Tremor, and Other Movement Disorders 2:00 p.m.  Presentation of Movement Disorders Research Award Recipient: Eduardo Tolosa, MD, PhD Barcelona, Spain

2:30 p.m. S27.003 Conversion from AbobotulinumtoxinA to IncobotulinumtoxinA Formulation of Botulinum Toxin: Clinic Experience in 257 Cases   Donald Grosset, Elaine Tyrrell, Katherine Grosset 2:45 p.m. S27.004 Clinimetric Testing of the Modules for the Comprehensive Cervical Dystonia Rating Scale (CCDRS)   Cynthia Comella, Joel Perlmutter, H. Jinnah, Charles Adler, Richard Barbano, Stewart Factor, Susan Fox, Christopher Goetz, Wendy Galpern, Joseph Jankovic, Laura Marsh, William Mcdonald, Stephen Reich, Ramon Rodriguez, Ami Rosen, William Severt, Tracy Waliczek, Glenn Stebbins 3:00 p.m. S27.005 Focused Ultrasound MR Guided Thalamotomy: 2 Year Follow-Up Safety and Efficacy Data   Binit Shah, Diane Huss, Tiffini Voss, Johanna Loomba, Mohamed Khaled, Madaline Harrison, W. Jeffrey Elias 3:15 p.m. S27.006 Predictors of Subjective Disability in Functional Movement Disorders   Tracy Fulton, Kathrin LaFaver, Sarah Kranick, Mark Hallett 3:30 p.m. S27.007 Clusterin CSF Levels in Differential Diagnosis of Neurodegenerative Disorders   Hana Prikrylova Vranova, Eva Henykova, Michaela Kaiserova, Katerina Mensikova, Miroslav Vastik, Jan Mares, Petr Hlustik, Jana Zapletalova, Miroslav Strnad, David Stejskal, Petr Kanovsky

S28 Aging, Dementia, and Cognitive and Behavioral Neurology: Dementia Genetics 2:00 p.m.  Presentation of Norman Geschwind Prize in Behavioral Neurology Recipient: Roy Hamilton, MD, MS Philadelphia, PA

2:15 p.m. S28.002 Late-onset Alzheimer Disease Neuropathology Genomic Screen Identifies Novel Loci for Neuritic Plaque and Other AD Neuropathology Features   Gary Beecham, Kara Hamilton, Gerard Schellenberg, Margaret Pericak-Vance, Thomas Montine 2:30 p.m. S28.003 Whole-exome Sequencing of Hispanic Early-onset Alzheimer Disease Families Identifies Rare Variants in Multiple Alzheimer-related Genes   Christiane Reitz, Brian Kunkle, Badri Vardarajan, Martin Kohli, Adam Naj, Patrice Whitehead, William Perry, Eden Martin, Gary Beecham, John Gilbert, Lindsay Farrer, Jonathan Haines, Gerard Schellenberg, Margaret Pericak-Vance, Richard Mayeux 2:45 p.m. S28.004 The Dissection of High-Penetrance Variants in Extended Late-onset Alzheimer Disease Families by Wholeexome Sequencing   Martin Kohli, Brian Kunkle, Adam Naj, Li-San Wang, Kara Hamilton, William Perry, Regina Carney, Patrice Whitehead, John Gilbert, Eden Martin, Gary Beecham, Jonathan Haines, Gerard Schellenberg, Stephan Zuchner, Margaret Pericak-Vance 3:00 p.m. S28.005 Transcript Profiling Analysis of Alzheimer’s Disease Brains.   Mariet Allen, Daniel Serie, Michael Walsh, Sun Zhifu, Saurabh Baheti, Fanggeng Zou, High Seng Chai, Curtis Younkin, Julia Crook, Vernon Pankratz, Minerva Carrasquillo, Asha Nair, Sumit Middha, Sooraj Maharjan, Thuy Nguyen, Li Ma, Kimberly Malphrus, Sarah Lincoln, Gina Bisceglio, Christopher Kolbert, Jin Jen, Ronald Petersen, Neill Graff-Radford, Dennis Dickson, Steven Younkin, Yan Asmann, Nilufer Taner 3:15 p.m. S28.006 Investigation of Transcriptional Regulation at the Alzheimer’s Disease Risk Loci.   Michaela Kachadoorian, Mariet Allen, Aditya Karhade, Lester Manly, Fanggeng Zou, High Seng Chai, Curtis Younkin, Julia Crook, Vernon Pankratz, Minerva Carrasquillo, Asha Nair, Sumit Middha, Sooraj Maharjan, Thuy Nguyen, Li Ma, Kimberly Malphrus, Sarah Lincoln, Gina Bisceglio, Christopher Kolbert, Jin Jen, Ronald Petersen, Neill Graff-Radford, Steven Younkin, Dennis Dickson, Nilufer Taner 3:30 p.m. S28.007 Screening for NOTCH3 Mutation in Patients with Subcortical Vascular Cognitive Impairment   Cindy Yoon, Young-Eun Kim, Jong-Won Kim, Duk L. Na, Chang-Seok Ki, Sang Won Seo

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2O14 Scientific Abstract Listing and Annual Meeting Information

Scientific Sessions S30 Education, Research, and History

2:00 p.m.  Presentation of Dreifuss-Penry Epilepsy Award

2:00 p.m.  Presentation of Lawrence C. McHenry Award: An Award for the History of Neurology

Recipient: Catherine Schevon, MD, PhD New York, NY

Recipient: Farrah Mateen, MD, PhD Boston, MA

2:15 p.m. S29.002 The Role of Toll-like Receptor 3 in Epileptogenesis   Felix Benninger, Adi Gross, Israel Steiner, Daniel Offen, Eitan Okun 2:30 p.m. S29.003 Association Between Human Herpes Virus 6 and Hippocampal Volume in Mesial Temporal Lobe Epilepsy   William Theodore, Emily Leibovitch, Bridgette Billioux, Sierra Germeyan, David Kalikhman, Sara Inati, John Heiss, Kareem Zaghloul, Steven Jacobson 2:45 p.m. S29.004 Sequential Versus Simultaneous Polytherapy in the Treatment of Status Epilepticus   Claude Wasterlain, Roger Baldwin, Jerome Niquet, Lucie Suchomelova 3:00 p.m. S29.005 Etiology of Pediatric Refractory Convulsive Status Epilepticus. Results from the Pediatric Status Epilepticus Research Group (pSERG)   William Gaillard, Howard Goodkin, Nicholas Abend, Satish Agadi, Ravindra Arya, Rajit Basu, Jessica Carpenter, Kevin Chapman, Nathan Dean, Tracy Glauser, Michele Jackson, Mohamad Mikati, Katrina Peariso, Geetanjali Rathore, Ivan Sanchez Fernandez, Robert Tasker, Alexis Topjian, David Turner, Angus Wilfong, Korwyn Williams, Tobias Loddenkemper

Recipient: Christopher Boes, MD Rochester, MN

2:30 p.m.  Presentation of S. Weir Mitchell Award Recipient: Michael Fox, MD, PhD Newton, MA

2:45 p.m. S30.004 The Effects of Repeated Quizzing on Long-Term Retention in AAN Annual Meeting Courses   Douglas Larsen, Wint Yan Aung, John Corboy, Deborah Friedman, Ann Tilton, Andrew Butler 3:00 p.m. S30.005 Osler, MacNalty, and the Recognition of Encephalitis Lethargica in England   Christopher Boes 3:15 p.m. S30.006 Closing the Loop: Mount Sinai Neurology Resident Clinical Acumen Assessment Project   Sarah Zubkov, Rachel Brandstadter, Christine Hannigan, Stephen Krieger 3:30 p.m. S30.007 Development of a Simulated Patient Exercise to Improve Acute Stroke Care by Neurology Residents   Adam Kelly, Ralph Jozefowicz

S31 General Neurology I 2:00 p.m. S31.001 Gadolinium Enhancement in Spondylotic Myelopathy Mimicking Tumors and Inflammation: A Case Series of 56 Patients   Eoin Flanagan, Karl Krecke, Richard Marsh, Caterina Giannini, Mark Keegan, Brian Weinshenker 2:15 p.m. S31.002 GLACIER: an Open-label, Randomized, Multicenter Study to Assess Safety and Tolerability of Glatiramer Acetate 40 mg/1mL 3-times Weekly Versus 20 mg/1mL Daily in Patients with Relapsing-Remitting Multiple Sclerosis   Wolinsky Jerry, Thor Borresen, Dennis Dietrich, Beverly Gilder, Yulia Sidi, Volker Knappertz, Scott Kolodny 2:30 p.m. S31.003 24-Month Efficacy and Safety of Glatiramer Acetate 40mg/1mL 3-Times Weekly: Open-label Extension Study of the GALA Trial in Subjects with Relapsing-Remitting Multiple Sclerosis   Omar Khan, Peter Rieckmann, Alexey Boyko, Krzysztof Selmaj, Hadas Barkay, Scott Kolodny, Robert Zivadinov 2:45 p.m. S31.004 B Cell-specific Signal in Whole Blood and Serum of NatalizumabTreated PML Patients Is Revealed Using Transcript and Protein Profiling   Tatiana Plavina, John Carulli, Huo Li, Daniel Park, Raghavendra Hosur, Normand Allaire, Peter Juhasz, Teresa Compton 3:00 p.m. S31.005 Neuroimaging and Clinical Features in Late Onset Alexander Disease   Jonathan Graff-Radford, Kara Schwartz, Ralitza Gavrilova, Daniel Lachance, Neeraj Kumar

3:15 p.m. S29.006 Hippocampal Malrotation Is Associated with Chromosome 22Q11.2 Microdeletion   Anne Bassett, Timo Krings, Eva Chow, Tim-Rasmus Kiehl, Danielle Andrade

3:15 p.m. S31.006 Dosing Feasibility and Pharmacokinetics by Seizure Type and Status, and Tolerability of Intranasal Diazepam in Adults with Epilepsy   Michael Sperling, Hussam Seif Eddeine, Kevin Haas, Gregory Krauss, Herbert Henney III, Adrian Rabinowicz, Gary Bream, David Squillacote, Enrique Carrazana

3:30 p.m. S29.007 Structural and Functional Implications of Modeling Non Synonymous Mutations in Patients with SCN1A-related Seizure Disorders   Mu Gao, Hongyi Zhou, Izabela Karbassi, Khalida Liaquat, Daniel Fischer, Jeffrey Skolnick, Joseph Higgins

3:30 p.m. S31.007 Dextromethorphan and Quinidine for Treatment of Pseudobulbar Affect (PBA): Time Course of PBA Episode Remission   Andrea Formella, Benjamin Brooks



S32 Headache: Basic Science and Imaging 2:00 p.m.  Presentation of Harold Wolff-John Graham: An Award for Headache/Facial Pain Research Recipient: Jakob Møller Hansen, MD, PhD Los Angeles, CA

2:15 p.m. S32.002 Ictal Lack of Binding of (11C)Dihydroergotamine to Brain Parenchyma Suggests That the Blood-Brain Barrier Remains Intact During Migraine Attacks   Christoph Schankin, Farooq Maniyar, Youngho Seo, Shashidar Kori, Michael Eller, Joseph Blecha, Stephanie Murphy, Till Sprenger, Henry VanBrocklin, Peter Goadsby 2:30 p.m. S32.003 Multi-Center 3T MRI Study of Thalamic Morphology in Migraine Using Label-Fusion-Based Segmentation and Deformation Based Morphometric Surface Analysis   Stefano Magon, Arne May, Anne Stankewitz, Peter Goadsby, Amy Tso, Messoud Ashina, Faisal Amin, Christian Seifert, Mallar Chakravarty, Jannis Müller, Till Sprenger 2:45 p.m. S32.004 Enhanced Pain-Induced Activation of Pain Processing Regions in Interictal Episodic Migraine   Todd Schwedt, Catherine Chong, Chia-Chun Chiang, Leslie Baxter, Bradley Schlaggar, David Dodick 3:00 p.m. S32.005 Therapeutic Efficacy of Transcranial Direct Current Stimulation in Trigeminal Neuralgia   Mark Obermann, Vera Bude, Dagny Holle, Tim Hagenacker, H. Diener, Zaza Katsarava 3:15 p.m. S32.006 Interictal Resting-State Connectivity of the Insula Is Altered in Migraine Without Aura   Amy Tso, Andrew Trujillo, Christine Guo, Peter Goadsby, William Seeley 3:30 p.m. S32.007 Autonomic Dysfunction in Migraine: Comparison Between Populations With and Without Orthostatic Intolerance   Mark Stillman, Lan Zhou, Fetnad Fouad-Terazi

S33 Cognition Fatigue in MS 2:00 p.m. S33.001 Processing Speed Test (PST): A Self-Administered iPad®-Based Tool for Assessing MS-Related Cognitive Dysfunction   Stephen Rao, Jay Alberts, Deborah Miller, Francois Bethoux, Jar-Chi Lee, Darlene Stough, Christine Reece, Lyla Mourany, David Schindler, Joshua Hirsch, Richard Rudick 2:15 p.m. S33.002 Structural MRI Corrrelates of Cognitive Impairment in Patients with Multiple Sclerosis: A Multi Center Study   Paolo Preziosa, Maria Rocca, Matteo Atzori, Frederik Barkhof, Nicola De Stefano, Christian Enzinger, Franz Fazekas, Antonio Gallo, Hanneke Hulst, Laura Mancini, Xavier Montalban, Elisabetta Pagani, Alex Rovira, Maria Laura Stromillo, Gioacchino Tedeschi, Giancarlo Comi, Massimo Filippi 2:30 p.m. S33.003 A Longitudinal Evaluation of MRI Predictors of Cognitive and Clinical Impairment in Multiple Sclerosis   Alfredo Damasceno, Benito Damasceno, Fernando Cendes 2:45 p.m. S33.004 Longitudinal Evaluation of Cognitive Functioning in Pediatric Multiple Sclerosis (MS): Report from the U.S. Pediatric Multiple Sclerosis Network   Lauren Krupp, Leigh Charvet, Ellen O’Donnell, Rebecca Cleary, Dana Serafin, Joy Parrish, Laura Julian, Natalie Baruch, Anita Belman, Ralph Benedict, Tanuja Chitnis, Jayne Ness, Moses Rodriguez, Emmanuelle Waubant, Bianca Weinstock-Guttman 3:00 p.m. S33.005 Longitudinal Evidence for Brain Reserve and Cognitive Reserve in Multiple Sclerosis: Larger Maximal Lifetime Brain Growth and Greater Intellectual Enrichment Attenuate Cognitive Decline Over 4.5 Years   James Sumowski, Maria Rocca, Victoria Leavitt, Jelena Dackovic, Sarlota Mesaros, Jelena Drulovic, John DeLuca, Massimo Filippi 3:15 p.m. S33.006 Social Cognition in Pediatric Multiple Sclerosis (MS)   Leigh Charvet, Rebecca Cleary, Katherine Vazquez, Livana Koznesoff, Kate Bartolotta, Jeremy Benhamroun, Lauren Krupp 3:30 p.m. S33.007 Deep Transcranial Magnet Stimulation Can Improve Depression and Fatigue in Multiple Sclerosis—a Clinical Phase I/IIa Study   Sven Schippling, Marina Tiede, Ina Lorenz, Caspar Pfueller, Jan Doerr, Judith Bellmann-Strobl, Abraham Zangen, Friedemann Paul, Gunnar Gaede

Fast, Easy Registration Online  ·  AAN.com/view/AM14

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Wednesday April 30

S29 Epilepsy and Clinical Neurophysiology: Inflammation, Status Epilepticus, and Genetics



Wednesday, April 30 I7  Emerging Therapeutic Advances in Multiple Sclerosis

2:00 p.m.–6:00 p.m.

Coordinators: Robert J. Fox, MD, FAAN and Eric Klawiter, MD Invited Speaker Session:  2:00 p.m.–4:30 p.m. 2:00 p.m.–2:10 p.m. Introduction 2:10 p.m.–2:35 p.m.

Treating Relapsing MS: Choosing Among the Options  Myla Goldman, MD

2:35 p.m.–3:00 p.m.

Treating Relapsing MS: Risk Stratification and Mitigation  Bruce A. C. Cree, MD, PhD, MCR

3:00 p.m.–3:25 p.m.

Is No Evidence of MS Disease Activity an Achievable Goal?  Robert A. Bermel, MD

3:25 p.m.–3:50 p.m.

Treating MS in 2020: Remyelination, Progressive MS, and Beyond  Catherine Lubetzki, MD

3:50 p.m.–4:15 p.m.

Treating Pediatric MS: Is It Different from Adults?  Tanuja Chitnis, MD

4:15 p.m.–4:30 p.m.

Questions and Answers

Poster Rounds:  4:30 p.m.–5:30 p.m. I7-1.001

S1P Receptor Modulation by Fingolimod Promotes Human Oligodendrocyte Progenitor Cell Differentiation Through Cell-Autonomous and Non-Cell Autonomous Mechanisms via ERK1/2 and p38MAPK Activation Qiaoling Cui, Timothy Kennedy, Guillermina Almazan, Jack Antel

I7-1.002 Peginterferon Beta-1a May

Improve Recovery Following Relapses: Data from the Pivotal Phase 3 ADVANCE Study in Patients with Relapsing-Remitting Multiple Sclerosis  Bernd Kieseier, Thomas Scott, Scott Newsome, Sarah Sheikh, Serena Hung, Xiaojun You, Bjorn Sperling

I7-1.003 A Nasal Anti-CD3 Vaccine

Treats a Model of Secondary Progressive MS by Inducing IL-10 Dependent T Regulatory Cells and Regulating CNS Innate Immunity  Lior Mayo, Andre Pires Da Cunha, Raymond Sobel, Hans Lassmann, Francisco Quintana, Howard Weiner

I7-1.004 Differential Effects of

Vitamin D in GA- versus IFN-Treated MS Patients  Dalia Rotstein, Brian Healy, Muhammad Taimur Malik, Robert Carruthers, Alexander Musallam, Pia Kivisakk, Bonnie Glanz, Tanuja Chitnis

I7-1.005 Therapeutic Plasma

Exchange in 90 GlucocorticosteroidUnresponsive Patients with Multiple Sclerosis—Prediction of Response  Johannes Ehler, Martin Sauer, Sebastian Koball, Steffen Mitzner, Heiko Hickstein, Reiner Benecke, Uwe Zettl

I7-1.006 A Phase II Trial of

Neuroprotection with Riluzole in Early Relapsing-Remitting MS: Lessons for Future Neuroprotection Trials Emmanuelle Waubant, Amir-Hadi Maghzi, Nisha Revirajan, Rebecca Spain, Laura Julian, Ellen Mowry, Jacqueline Marcus, Shuang Liu, Ari Green, Charles McCulloch, Daniel Pelletier

I7-1.007

The MIRROR Study: A Randomized, Double-blind, Placebocontrolled, Parallel-group, Dose-ranging Study to Investigate the Safety and MRI Efficacy of Subcutaneous Ofatumumab in Subjects with Relapsing-Remitting Multiple Sclerosis (RRMS)  Amit Bar-Or, Richard Grove, Daren Austin, Jerry Tolson, Susan Vanmeter, Eric Lewis, Per Solberg Sorensen

I7-1.009 Laquinimod Reduces

Neuronal Injury Through Inhibiting Microglial Activation  Voon Wee Yong, Manoj Mishra, Janet Wang, Michael Keough, Claudia Silva, Yan Fan, Scott Sloka, Liat Hayardeny

I7-1.010

I7-1.008 Randomized Controlled

Alemtuzumab Improves Visual Outcomes Versus Subcutaneous Interferon Beta-1a in Patients with Active Relapsing-Remitting Multiple Sclerosis (RRMS) Who Relapsed on Prior Therapy: Analysis from the CARE-MS II Study  Jennifer Graves, Laura Balcer, Jeffrey Palmer, David Margolin, Steven Galetta

5:40 p.m.

5:45 p.m.

I7-2.004

5:50 p.m.

I7-2.005

Trial of CI Therapy for Progressive MS: Increased Real-World Function and Neuroplasticity on MRI  Victor Mark, Edward Taub, Gitendra Uswatte, Gary Cutter, David Morris, Staci McKay, Mary Bowman, Michelle Haddad, Tyler Rickards, Chelsey Sterling

Data Blitz:  5:30 p.m.–6:00 p.m. 5:30 p.m.

I7-2.001

IRX4204: A Clinical Stage, Potent, and Highly Selective RXR Agonist Compound Is Brain Penetrant, and Promotes Differentiation of Oligodendrocyte Precursor Cells (OPCs) In Vitro  Martin Sanders, Satish Medicetty, Rosh Chandraratna

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5:35 p.m.

I7-2.002

A Combination Trial of Estriol Plus Glatimer Acetate in Relapsing-Remitting Multiple Sclerosis  Rhonda Voskuhl, HeJing Wang, T.C. Jackson Wu, Nancy Sicotte, Angela Bates, Gary Beaver, John Corboy, Anne Cross, Suhayl Dhib-Jalbut, Corey Ford, Barbara Giesser, Dina Jacobs, Sharon Lynch, Andrew Pachner, Michael Racke, John Ratchford, Anthony Reder, John Rose, Dean Wingerchuk, Margaret Burnett, Chi Hong Tseng, Robert Elashoff

I7-2.003

Safety and Tolerability of Delayed-Release Dimethyl Fumarate Administered as Add-on Therapy to Beta Interferons or Glatiramer Acetate in Relapsing-Remitting Multiple Sclerosis (RRMS) Patients  Vissia Viglietta, Timothy Vollmer, Ray Zhang, Mark Novas, Sarah Sheikh, Robert Fox

2O14 Scientific Abstract Listing and Annual Meeting Information

Deep Transcranial Magnet Stimulation Can Improve Depression and Fatigue in Multiple Sclerosis—a Clinical Phase I/ IIa Study  Sven Schippling, Marina Tiede, Ina Lorenz, Caspar Pfueller, Jan Doerr, Judith Bellmann-Strobl, Abraham Zangen, Friedemann Paul, Gunnar Gaede Stopping Disease Modifying Therapy in Progressive Multiple Sclerosis—a Prospective Study  Gary Birnbaum

Integrated Neuroscience Sessions I8 Clinical Decision Making After the Dust Settles on Clinical Trials

2:00 p.m.–6:00 p.m.

Coordinators: Barbara G. Vickrey, MD, MPH, FAAN and Linda S. Williams, MD, FAAN Invited Speaker Session:  2:00 p.m.–4:30 p.m. 2:00 p.m.–2:10 p.m. Introduction 2:10 p.m.–2:40 p.m.

Intervention Research on Improving Access to and Quality of Neurologic Care  Ray Dorsey, MD, MBA

2:40 p.m.–3:10 p.m.

Effectiveness Research in Neurology  Seemant Chaturvedi MD, FAAN, FAHA

3:10 p.m.–3:40 p.m.

Translating Neurologic Advancements into Practice through Decision Support  Eric M. Cheng MD, MS, FAAN

3:40 p.m.–4:10 p.m.

Research on Incorporating Patient Preferences in Neurologic Care  Adam Kelly, MD

4:10 p.m.–4:30 p.m.

Questions and Answers

Poster Rounds:  4:30 p.m.–5:30 p.m. Patients’ Preferences for Communication About Advanced Care Planning Keiran Tuck, Lissa Brod, John Nutt, Erik Fromme

I8-1.002 Vascular Parkinsonism in

a Tertiary Care Stroke Prevention Clinic: Prevalence and Development of a New Screening Strategy  Herbert Manosalva Alzate, Thomas Jeerakathil, Maher Saqqur, Richard Camicioli, Oksana Suchowersky

I8-1.003 Multiple Sclerosis

Documentation System MSDS3D— Innovative Management of Patients with Multiple Sclerosis  Judith Eisele, Raimar Kern, Suhrbier Alexander, Lars Großmann, Thorsten Schultheiss, Tjalf Ziemssen

I8-1.004 Neuro-oncology

Telemedicine Follow-up Visits Richard Green, Emily Woyshner, Amanda Hauser Dehaven

I8-1.005 Long Term Efficacy of

Outpatient Interdisciplinary Treatment for Patients Suffering from Chronic Headaches  Mark Stillman, Steven Krause

I8-1.006 Adherence to Oral

I8-1.008 Treatment Trends in

I8-1.007 Influence of CREST on

I8-1.009 Antiepileptic Drug

5:40 p.m.

I8-2.003

5:50 p.m.

5:45 p.m.

I8-2.004

Migraine Preventive Medications Among Patients with Chronic Migraine: Analysis of a Large US Health Insurance Claims Database  Zsolt Hepp, David Dodick, Sepideh Varon, Patrick Gillard, Ryan Hansen, Emily Devine CEA and CAS Trends in Women—Do the Results Matter?  Shahram Khalid, Sanath Reddy, Seemant Chaturvedi, Kumar Rajamani, Pratik Bhattacharya, Navid SerajiBozorgzad

Management of Intracranial Stenosis in the Pre- and Post-sammpris Era Swaroop Pawar, Tanya Turan, George Cotsonis, Michael Lynn, Rahim Wooley, Barney Stern, Colin Derdeyn, David Fiorella, Marc Chimowitz Prescribing for OEF/OIFVeterans with NewOnset Epilepsy: 2008-2010  Mary Jo Pugh, Anne Van Cott, Christine Baca, Megan Amuan

Data Blitz:  5:30 p.m.–6:00 p.m. 5:30 p.m.

I8-2.001

Identifying Palliative Care Needs in the Neurological Intensive Care Unit  Claire Creutzfeldt, J Curtis

5:35 p.m.

I8-2.002

Appropriateness of Dopamine Antagonist Prescribing in Hospitalized Patients with Dopamine Requiring Diseases After Implementation of an Automated Prescribing Alert System  Marie Morris, Allison Willis, Franklin McCann, Angela Birke, Brad Racette

Development and Implementation of a Quality Improvement Strategy for Obtaining Muscle Biopsies Utilizing DMAIC Methodology  Charles Kassardjian, Michelle Williamson, Dorothy Van Buskirk, Floranne Ernste, Andrea Leep Hunderfund A Comparison of Co-located and Traditional Outpatient Consultation for the Treatment of ADHD in Two Urban Medical Homes: Costs and Outcomes  David Urion



I8-2.005

Malformation Risks of Antiepileptic Drug Monotherapies in Pregnancy: An Update From the UK and Ireland Epilepsy and Pregnancy Registers  Ellen Campbell, Fiona Kennedy, Aline Russell, W Smithson, Linda Parsons, Beth Irwin, Brenda Liggan, Norman Delanty, Patrick Morrison, Stephen Hunt, John Craig, Jim Morrow

Fast, Easy Registration Online  ·  AAN.com/view/AM14

93

Wednesday April 30

I8-1.001 Parkinson’s Disease



Wednesday, April 30 P5  Poster Session V First Authors stand by Posters from 5:00 p.m.–6:30 p.m.

3:00 p.m.–6:30 p.m.

 oster Discussion Session: P Cerebrovascular Disease and Interventional Neurology II Utilizing a guided tour format, topic experts will lead attendees around the ten posters in the poster discussion session and facilitate questions with poster authors during the 90-minute author stand-by time.

P5.001

MRI Detection of Blood After Perimesencephalic Subarachnoid Hemorrhage  Jordan Samuels, James Conners, Sarah Song, Shawna Cutting, Vivien Lee

P5.002

Use of Apixaban and Warfarin in Patients Undergoing Procedures: Insights from ARISTOTLE  Renato Lopes, David Garcia, Daniel Wojdyla, Paul Dorian, John Alexander, Lars Wallentin, Fernando Lanas, Michael Hanna, Claes Held, Christopher Granger

P5.004

Oral Anticoagulant Therapy Is Associated with Cerebral Microbleeds  Saloua Akoudad, Sirwan Darweesh, Maarten Leening, Peter Koudstaal, Albert Hofman, Aad Van Der Lugt, Bruno Stricker, Mohammad Ikram, Meike Vernooij

P5.005

The Incidence of Secondary Stroke Prevention Medication Following Hospitalization for Ischemic Stroke Justin Blackburn, Hong Zhao, Meredith Kilgore, Karen Albright

P5.006

Effects of Angiopoietin-1 on Hemorrhagic Transformation and Cerebral Edema After Tissue Plasminogen Activator Treatment for Ischemic Stroke Masato Kanazawa, Kunio Kawamura, Tetsuya Takahashi, Hironaka Igarashi, Tsutomu Nakada, Masatoyo Nishizawa, Takayoshi Shimohata

P5.008

P5.007

P5.009

The Influence of Obesity on Outcomes After Intravenous Thrombolysis for Acute Ischemic Stroke  AV Nickles, Saqib Chaudry, Syed Hussain, M J Reeves

P5.003

Effect of Apixaban on AllCause Mortality in Atrial Fibrillation: An Imputed Placebo Analysis  John McMurray, Robert Hart, Greg Flaker, Renato Lopes, Junyuan Wang, Michael Hanna, John Alexander, Christopher Granger, Lars Wallentin

A Utility-Weighted Modified Rankin Scale: Derivation and Application to Completed Stroke Trials Napasri Chaisinanunkul, Jeffrey Saver, Tudor Jovin, Scott Berry, Roger Lewis, Kennedy Lees, Anthony Furlan, Blaise Baxter, Helmi Lutsep, Marc Ribo, Olav Jansen, Rishi Gupta, Vitor Pereira-Mendes, Raul Nogueira Geography of Stroke Mortality: Hotspotting Areas for Targeted Interventions  Catherine Wolff, Michael Mullen, Douglas Wiebe, Charles Branas, Brendan Carr

P5.010

Predictors of Neurological Deficit After Endovascular Treatment of Cerebral Arteriovenous Malformations and Functional Repercussion in Prospective Follow-Up  Juan Carlos Llibre, Jose Antonio Jordan

NEW! e  Poster Session: MS and CNS Inflammatory Disease II The ePoster session will feature a selection of posters to be presented digitally, rather than in the traditional format. Authors will be able to take advantage of the format to highlight compelling visual features such as images and videos. See poster map on page 47 for location.

P5.011

Therapeutic Plasma Exchange in 90 Glucocorticosteroid-unresponsive Patients with Multiple Sclerosis— Prediction of Response  Johannes Ehler, Martin Sauer, Sebastian Koball, Steffen Mitzner, Heiko Hickstein, Reiner Benecke, Uwe Zettl

P5.012

MRI Detection of Pial and Subpial Abnormalities in the MS Spinal Cord  Hugh Kearney, Marios Yiannakas, Rebecca Samson, Claudia WheelerKingshott, Olga Ciccarelli, David Miller

P5.013

Phenotypic Differences in the Distribution of Gray Matter Lesions in Multiple Sclerosis and Their Relevance to Cognition  Varun Sethi, Tarek Yousry, Nils Muhlert, Daniel Tozer, Daniel Altmann, Maria Ron, Claudia Wheeler-Kingshott, David Miller, Declan Chard

P5.014

EDSS and MSFC Incompletely Capture Patient Reported Disability in a Longitudinal Cohort of Patients with Multiple Sclerosis  Carolyn Bevan, Pierre-Antoine Gourraud, Monica Bucci, Regina Schlaeger, Refujia Gomez, Caroline Ciocca, Rachel Kanner, William Stern, Alan Evangelista, Samuel Arnow, Aya Abounasr, Adam Santaniello, Jeffrey Gelfand, H. Von Budingen, Ari Green, Douglas Goodin, Sergio Baranzini, Stephen Hauser, Roland Henry, Bruce Cree

94

P5.015

The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS): Normative Values with Gender, Age and Education Corrections in the Italian Population  Maria Pia Amato, Emilio Portaccio, Claudia Niccolai, Bahia Hakiki, Benedetta Goretti, Andrea Sturchio, Vittorio Martinelli, Monica Falautano, Eleonora Minacapelli, Ugo Nocentini, Chiara Incerti, Maria Marrosu, Eleonora Cocco, Monica Murgia, Giuseppe Fenu, Ferdinando Ivano Ambra, Elisabetta Garofalo, Maurizio Maddestra, Marilena Consalvo, Giovanni Zimatore, Nunzia Alessandra Losignore, Alessandra Lugaresi, Erika Pietrolongo, Rosa Viterbo, Maria Trojano

P5.016

Vitamin D as Predictor of Multiple Sclerosis Activity and Progression in Patients with CIS Treated Early with Interferon Beta-1b Alberto Ascherio, Kassandra Munger, Rick White, Karl Kochert, Kelly Claire Simon, Mark Freedman, Hans Hartung, David Miller, Xavier Montalban, Gilles Edan, Frederik Barkhof, Dirk Pleimes, Rupert Sandbrink, Ludwig Kappos, Christoph Pohl

P5.017

A Phase II Trial of Neuroprotection with Riluzole in Early Relapsing-Remitting MS: Lessons for Future Neuroprotection Trials Emmanuelle Waubant, Amir-Hadi Maghzi, Nisha Revirajan, Rebecca Spain, Laura Julian, Ellen Mowry, Jacqueline Marcus, Shuang Liu, Ari Green, Charles McCulloch, Daniel Pelletier

P5.018

Implicating MicroRNAs as Regulators of Microglia and Astrocyte Responses in Human CNS Inflammatory Disease  Craig Moore, Vijayaraghava Rao, Shih-Chieh Fuh, Barry Bedell, Samuel Ludwin, Amit Bar-Or, Jack Antel

P5.019

Grey Matter Expression of Fetuin-A Correlates with Cortical Demyelination in Multiple Sclerosis Mark Landy, Ying Liu, Violaine Harris, Saud Sadiq

P5.020 WITHDRAWN

2O14 Scientific Abstract Listing and Annual Meeting Information

Poster Session V P5.035

P5.048

P5.021

The Utility of Paraneoplastic Serology in the Saskatoon Health Region  Ilia Poliakov, Gary Hunter

Is Intracranial Arterial Involvement a Subgroup of Neuro-Behcet Syndrome?  Burcu Zeydan, Ugur Uygunoglu, Melih Tutuncu, Cengiz Yalcinkaya, Ayse Altintas, Sabahattin Saipoglu, Aksel Siva

America’s First Epilepsy Journal: Transactions of the National Association of the Study of Epilepsy and Care and Treatment of Epileptics Edward Fine, Alyssa Fiddler

Epilepsy and Clinical Neurophysiology (EEG): Epidemiology and Health Care Utilization

P5.022

P5.036

P5.049

P5.062

Isolated Cerebral Mucormycosis: A Case Report Monica Dhakar, Mahmoud Rayes, Kupsky Williams, Alexandros Tselis, Gregory Norris

P5.023

Role of Neurological Consultation in Evaluating Syncope  Adithya Sivaraju, Appaji Rayi, David Marks

P5.024

Anomalous Origins of Bilateral Anterior Cerebral Arteries (ACA) from the Cavernous Internal Carotid Arteries (ICA).  Swetha Pedavally, Matthew Omojola

P5.025

A Case Report of a Transient Lesion of the Splenium Resulting from Vasospasm Secondary to Pituitary Apoplexy  Tooba Fayyaz, Jocelyn Cheng

P5.026

Rare Neurological Complications After Epidural Anesthesia in Obstetric Patients: 2 Case Reports Gayane Melikyan, Naveed Akhtar, Saadat Kamran, Hassan Al-hail, Dirk Deleu

P5.027

Tongue Abnormalities on MRI Associated with Severity and Progression in ALS  César Escamilla, Hector Martinez, Jorge Moreno-Cuevas, Maria Teresa Gonzale-Garza, Sergio Salazar Marioni, Alfonso Gil Valadez

P5.028

Management Standardization of Limbic Encephalitis and Rapidly Progressive Dementia Elmoatazbellah Ibrahim, Joel Phillips, Andrew Biondo

P5.029

Anti-Aquaporin 4 Autoantibodies in Patients with Systemic Lupus Erythematosus Without CNS Involvement: A long-term assessment  Ioanna Tatouli, Harry Alexopoulos, Sofia Akrivou, Athanasios Tzioufas, Marinos Dalakas

P5.037

Clinical Prodromes of Neurodegeneration in Anderson-Fabry Disease  Matthias Löhle, Alan Milligan, Linda Richfield, Heinz Reichmann, Derralynn Hughes, Atul Mehta, Anthony Schapira

P5.038

This Is a Novel Case a Variant of Miller-Fisher Syndrome with a Positve Anti-GQ1b Antibody Presenting as Parinaud’s Syndrome.  Rick Magun, Jamie Silva

P5.039

Evaluating the True Clinical Relevance of Genomic Intervals Associated with Amyotrophic Lateral Sclerosis Kevin Kenna, Russell Mc Laughlin, Susan Byrne, Marwa Elamin, Mark Heverin, Elaine Kenny, Paul Cormican, Derek Morris, Colette Donaghy, Daniel Bradley, Orla Hardiman

P5.040

Alcoholic Wernicke’s Encephalopathy with Cranial Nerve XII Involvement on MRI  Maya Lichtenstein, Dan Nguyen

P5.041

Delayed Recognition of POEMS  Hai Chen, Benjamin Greenberg, Steven Vernino

First-time Seizure or Seizurelike Presentations in U.S. Adult Emergency Departments 2007-2010  Wenyu Sun, Anbesaw Selassie, Paul Pritchard

P5.050

Necessity of Emergency Medical Care for Patients with Epilepsy Presenting with Typical Seizures Timothy Rust, Bassel Shneker

P5.051

Economic Outcomes in Patients Receiving Anti-epileptic Drug (AED) Adjunctive Therapy  Zhixiao Wang, Xuan Li, Annette Powers, Jose Cavazos

Epilepsy and Clinical Neurophysiology: EEG P5.052

Utility of After Hours Emergency Electroencephalograms Ram Narayan, Puneet Gupta, Barbara Voth, Lakshmi Beeravolu, Ryan Hays, Pradeep Modur, Paul Van Ness, Mark Agostini

P5.053

Usefulness of Emergent Electro-Encephalogram In Known Epileptic Patients  Louise Tyvaert, Marie Girot, Xavier Lenne, Pierre Williate, William Szurhaj, Stephanie Leblanc, Maxime Chochoi, Herve Hubert, Philippe Derambure

P5.054

Use of Prolonged VEEG Monitoring in Children with First Unprovoked Seizure  Misbah Salam, Anjum Hashim, Jasmine Singh

P5.055

Frequent Additional Epileptogenic Abnormalities Detected with Inpatient Long-Term EEG Monitoring  Ehtesham Khalid, Shobhit Sinha, Khurram Siddiqui

A Presentation of Progressive Multifocal Leukoenceophalopathy Leading to Diagnosis of Underlying Marginal Zone Lymphoma: An Unusual Antecedent Cause of Immunosuppression. Alexander Hartmann, Sara Mayer

Epilepsy and Clinical Neurophysiology (EEG): Quality Improvement, Health Care Utilization, and History of Epilepsy

P5.030

Multiple Autoimmune Antibody Limbic Encephalitis: A Case in a Pregnant Woman  Meha Goyal, Kasey Gildersleeve, Stuart Tomko, Joseph Kass

P5.042

Variation in Quality of Epilepsy Care and Association with Seizure Control.  Lidia Moura, Jonathan de Jesus, Rogger Andrade, Daniel Hoch

Should Idiopathic Generalized Epilepsy be Labeled “generalized” or “System” Epilepsy Syndromes? Istabrak Abdelkefi, Yousser Hizem, Imen Kacem, Mouna Ben Djebara, Amina Gargouri, Olivier Dulac, Riadh Gouider

P5.031 Hemophagocytic

P5.043

P5.057

Lymphohystiocytosis Associated with Encephalitis: Two Case Reports Sheetal Sheth, Carl Gold, Emma Meyers, Amy Jongeling, Stephan Mayer, Sachin Agarwal, Jan Claassen, Brandon Foreman

P5.032

Extending the Olive Branch: A Cost-Benefit Analysis of Thymectomy in Myasthenia Gravis  Shrikant Mishra, Nasheed Jamal, Poonum Chaturvedi, Bhavesh Trikamji

P5.033

Determination of Antibodies to GAD67 and Other Antigens in Patients with GAD65 Antibody-associated Syndromes  Núria Gresa-Arribas, Helena Ariño, Lidia Sabater, Eva Caballero, Mercè Alba, Eugenia Martínez-Hernandez, Mar Petit, Albert Saiz, Josep Dalmau, Francesc Graus

P5.034

Basal Ganglia Encephalitis and Autoimmune Retinitis Associated with Influenza B  Barbara Graves, Jonathan Hosey

Implementation of an Easyto-use Database for the Assessment of Physician Performance in Epilepsy Care  Rodolfo Callejas, Yamil Matuk-Perez, Daniel Vargas-Mendez, Nephtali CruzReyes, Nelson Garcia, Ildefonso RodriguezLeyva

P5.044

Complications in the Epilepsy Monitoring Unit: A Nationwide Study  Monica Dhakar, Maysaa Basha

P5.045

How Long Is Long Enough? The Utility of Prolonged Inpatient Video EEG Monitoring  Brian Moseley, Sandra Dewar, Zulfi Haneef, John Stern

P5.046

Epidemiological Pilot Analysis of Epilepsy Patients in a Community Clinic Aims to Inform Effective Care  Laura Karas, Corey Goldsmith, Sara Ruppelt, Alica Goldman

P5.047

Epilepsy Surgery: Historical Perspective  Pawan Rawal



P5.056

“Re-build Up” Phenomenon Revisited  Hesham Allam, Daniel Weber, Stanley Iyadurai

P5.058

Infraslow Delta Co-exists with High Frequency Oscillation in Cases of Ictal Internal Vibration Aura  Hisanori Hasegawa

P5.059

Quantitative EEG (qEEG) as Marker for Mild Cognitive Impairment (MCI) in Patients with Parkinson’s Disease (PD)  Habib Bousleiman, Shaheen Ahmed, Martin Hardmeier, Florian Hatz, Christian Schindler, Volker Roth, Ronan Zimmermann, Ute Gschwandtner, Peter Fuhr

P5.060

Triphasic Waves and Epileptiform Correlates on Electroencephalogram  Alyssa Fiddler, Osman Farooq, Barbara Teter, Katelyn Kavak, Arie Weinstock

P5.061

When Should We Treat Periodic Lateralized Epileptiform Discharges (PLEDS)  Ahmad Solaiman, Anza Memon, Maysaa Basha, Lusine Avedian

Hospitalization Rates and Early Versus Late Addition of Adjunctive Anti-epileptic Drugs: A Retrospective Study in a Commercially-Insured U.S. Population  Fulton Velez, Thirupathi Pattipaka, Maria Malmenäs

P5.063

Knowledge About Sudden Unexpected Death in Epilepsy Among Health Personnel, Epilepsy Patients and Their Relatives. A Pilot Survey in Honduras.  Reyna Duron, Juan Argenal, Sylvia Gonzalez-Canelo, Dario ZunigaMartinez, Lupe Martinez, Susan PietschEscueta

P5.064

A Unique Partnership for Research in Epilepsy Outcomes: The Emory University and UCB Pharma Collaboration  Sandra Helmers, Fred Cox, David Thurman, R Faught, Archna Patel, Tracy Durgin, Patty Fritz, Kelly Simontacchi, Akshatha Kalsanka Pai

P5.065

Risk of Bone Fractures Among Epilepsy Patients in the United States: An Analysis of a Large Administrative Claims Database  Fulton Velez, Joseph Menzin, Michael Munsell, Molly Frean

P5.066

Known Epileptic Patients Use of Emergency Departments  Marie Girot, Philippe Derambure, Maxime Chochoi, Stephanie Leblanc, Patrick Goldstein, William Szurhaj, Pierre Williate, Xavier Lenne, Eric Wiel, Herve Hubert, Florence Richard, Louise Tyvaert

P5.067

Known Epileptic Patients Use of Resources of Emergency Departments  Marie Girot, Xavier Lenne, Stephanie Leblanc, William Szurhaj, Maxime Chochoi, Patrick Goldstein, Pierre Williate, Eric Wiel, Herve Hubert, Philippe Derambure, Louise Tyvaert

P5.068

Severe Overutilization of the Emergency Department in Patients with Uncontrolled Epilepsy  Neha Vijayvargiya, Steven Tobochnik, Kenneth Walsh, Camilo Gutierrez, Wayne Satz, Mercedes Jacobson

P5.069

Comparison of Health Care Resource Utilization and Costs in Treatment-Adherent Patients with Epilepsy With and Without Breakthrough Seizures in A U.S. Managed Care Population Charles Makin, Allison Petrilla, Victoria Divino, Vamsi Bollu, Fulton Velez, Shawn Hallinan, Alan Ettinger

P5.070

Resource Utilization in Patients with Suspected Psychogenic Non-epileptic Seizures and Drug Resistant Epilepsy in the Harris County Health District Between 2009 and 2012 Brian Wolf, Bonnie Hayashi, Ezekiel Sachs, Colin Van Hook, Dona Murphey, Corey Goldsmith

P5.071

The Economic Burden of Uncontrolled Epilepsy: A Retrospective Study in a Commercially-Insured U.S. Population  Maria Malmenas, Thirupathi Pattipaka, Vamsi Bollu, Fulton Velez

Fast, Easy Registration Online  ·  AAN.com/view/AM14

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Wednesday April 30

General Neurology IV



Wednesday, April 30 P5.072

Real-World Persistence and Treatment Failure Associated with First Line Use of Antiepileptic Drug Treatment in a Large U.S. Managed Care Population  Victoria Divino, Allison Petrilla, Shawn Hallinan, Vamsi Bollu, Fulton Velez, Alan Ettinger, Charles Makin

ALS: Epidemiology and Registries P5.073

Increased Prevalence of ALS in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans Sasha Zivkovic, Anne Van Cott, Huned Patwa, Mary Jo Pugh

P5.074

Verification of Amyotrophic Lateral Sclerosis (ALS) Cases Reported to the State and Metropolitan Area ALS Surveillance Projects  Wendy Kaye, Laurie Wagner, Vinicius Antao, Eric Sorenson

P5.075

State and Metropolitan Areabased Amyotrophic Lateral Sclerosis (ALS) Surveillance  Laurie Wagner, Wendy Kaye, Heather Jordan, Lindsay Rechtman, Maggie Ritsick, Marchelle Sanchez

P5.076

The Northeast ALS Consortium (NEALS) Upper Motor Neuron Disease (UMND) Registry  Alyssa Murphy, Lorena Loci, Hiroshi Mitsumoto, Catherine Lomen-Hoerth, Yasushi Kisanuki, Jinsy Andrews, Merit Cudkowicz, Nazem Atassi

P5.077

Using the National Amyotrophic Lateral Sclerosis Registry as a Subject Recruitment Tool for Research D. Kevin Horton, Vinicius Antao, Paul Mehta

P5.078

National ALS Biorepository Feasibility Study  Wendy Kaye, Laurie Wagner

P5.079

Enhancements to the U.S. National Amyotrophic Lateral Sclerosis (ALS) Registry  Paul Mehta, Vinicius Antao, D. Kevin Horton

P5.080

Findings from the New Jersey State-wide Amyotrophic Lateral Sclerosis (ALS) Surveillance Project  Heather Jordan, Jerald Fagliano, Daniel Lefkowitz, Lindsay Rechtman, Wendy Kaye

P5.081

Cognitive Reserve in ALS with Comorbid Frontotemporal Dementia (FTD): A Population-Based Study Antonio Canosa, Anna Montuschi, Barbara Iazzolino, Andrea Calvo, Cristina Moglia, Davide Bertuzzo, Leonardo Lopiano, Gabriella Restagno, Maura Brunetti, Irene Ossola, Anna Lo Presti, Stefania Cammarosano, Adriano Chio

P5.084

Physical Activity Profile and Barriers to Physical Activity in Individuals with Myotonic Dystrophy  Katy Eichinger, Jeanne Dekdebrun, Nuran Dilek, Shree Pandya, Ding-Geng Chen

P5.095

P5.085

P5.096

Brain Gray Matter and White Matter Alterations in Patients with Myotonic Dystrophy 1  Stojan Peric, Federica Agosta, Francesca Caso, Vidosava Rakocevic-Stojanovic, Giancarlo Comi, Vladimir Kostic, Massimo Filippi

P5.086

Congenital Centronuclear Myopathy Mimicking Congenital Myotonic Dystrophy  Watcharasarn Rattananan, Jill Blandford, Gwendolyn Claussen, Shin Oh, Mohammad Alsharabati

P5.087

Electrical Impedance Myography Discriminates Congenital Muscular Dystrophy from Controls Daniel Schwartz, Anam Salman, Janannaz Dastgir, Barbara Lear, Carsten Bonnemann, Tanya Lehky

Hereditary Inclusion Body Myositis (IBM2) with a GNE c.2228 T>C Mutation in 3 Saudi Arabian Families.  Ahmed Basndwah, Enass AlMowalad, Yousef Al-Said, Edward Cupler

P5.098

Immunotherapy for Respiratory Complications of Sporadic Late Onset Nemaline Myopathy (SLONM) with Monoclonal Gammopathy  Nancy Rosales, Mihael Varosanec, Ramon Lugo, Richard Prayson, Megan Rahmlow

P5.099 Human α7 Integrin Gene

P5.108

Can Ultrasonography of Median Nerve Differentiate Between Mild, Moderate and Severe Carpal Tunnel Syndrome?  Vasudeva Iyer

P5.109

The Specificity of Prolonged CMAP Durations and Severe CMAP Reductions in Critical Illness Neuromyopathy  Christopher Kramer, Andrea Boon, C. Harper, Brent Goodman

P5.110

Longitudinal Quantitative EMG Findings During Reinnervation After Complete Nerve Lesions  Christian Krarup, Michel Boeckstyns, Allan Ibsen, Simon Archibald

Cerebrovascular Disease and Interventional Neurology: Epidemiology

P5.100

Desmin C-terminus Tail Mutation Is a New Cause of Autosomal Dominant Limb-girdle Muscular dystrophy  Joshua Lovinger, Anna Szekely, Huned Patwa, Zarife Sahenk

Stroke and Non Convulsive Status Epilepticus. A Topographic and Prognosis Description.  Francisco Muñoz Giacomelli, Analia Calle, Maria Gonzalez Toledo, Fatima Pagani Cassara, Agustina Tamargo, Alejandro Thomson, Diego Nadile, Francisco Klein

P5.090

Neurophysiology/EMG

P5.113

Evaluation in 476 Turkish Dystrophinopathy Patients  Hacer Durmus, Nihan ErginelUnaltuna, Poda Mehves, Arman Çakar, Ayca Altinkaya, Filiz Guclu-Geyik, Feza Deymeer, Yesim Parman, Asli Tolun, Piraye Serdaroglu Sociodemographic and Health Related Profile of Adults with Duchenne/ Becker Muscular Dystrophy (DBMD): Data from the Muscular Dystrophy Surveillance, Tracking and Research Network (MD STARnet)  Shree Pandya, Anil Kumar, Kathy James, Christine Westfield, Emma Ciafaloni, Christopher Cunniff, Paul Romitti, Richard Moxley

P5.091

Baseline Performance on 6MWT Correlates with Other Functional Outcomes in a Phase IIb Study of ExonSkipping Antisense Oligonucleotide Eteplirsen for Use in Duchenne Muscular Dystrophy (DMD)  Jihad Saoud, Jerry Mendell, Louise Rodino-Klapac, Zarife Sahenk, Kandice Roush, Loren Bird, Linda Lowes, Lindsay Alfano, Ana Maria Gomez Ramirez, Sarah Lewis, Vinod Malik, Kim Shontz, Christopher Shilling, Peter Sazani, Edward Kaye

P5.092

P5.093

96

P5.097

Ulnar Palm to Finger Sensory Nerve Conduction  Eduardo Davidovich, Osvaldo Nascimento, Bruno Coutinho, Victor Kosac

P5.089 Genotype-Phenotype

Muscular Dystrophies Correlation Between Muscle Histopathology Impairment and Spliceopathy in Myotonic Dystrophies  Giovanni Meola, Enrico Bugiardini, Giuliana Rossi, Laura Valentina Renna, Annalisa Botta, Rosanna Cardani

Analysis of Myostain and Related Proteins in a Cardiotoxin Injury Muscle Atrophy Model  Kenya Murata, Hidefumi Ito

P5.107

(ITGΑ7) Delivered by Adeno-Associated Virus Reverses the Phenotype of the Double Knock Out (DKO) Mouse Devoid of Dystrophin and Utrophin  Kristin Heller, Chrystal Montgomery, Kim Shontz, Paul Janssen, Reed Clark, Jerry Mendell, Louise Rodino-Klapac

Telemedicine in the Home for Veterans with Amyotrophic Lateral Sclerosis  Richard Bedlack

P5.083

A Novel Form of Nemaline Myopathy Caused by an In-Frame Deletion in TNNT1  Sarada Sakamuri, Carly Siskind, Karolina Watson, Thomas Winder, Hannes Vogel, John Day

To Report Clinical Heterogeneity of Facio-scapulo-humeral Muscular Dystrophy in Which Two Patients Presented with Recurrent Facial Palsy  Uzma Usman, Bilal Hameed, Johnny Salameh

P5.088

Elucidating the Mechanism of Anoctamin 5 Deficiency with a Novel KO Mouse Model  Danielle Griffin, Eric Pozsgai, William Grose, Kristin Heller, Jerry Mendell, Zarife Sahenk, Louise Rodino-Klapac

P5.082

3:00 p.m.–6:30 p.m.

C. Elegans as a model System to Study Nemaline Myopathy  Ge Xiong, Ken Choe, David Leung, Hiroshi Qadota, Guy Benian, Desmond Zeng, Karen McFarland, Tetsuo Ashizawa

P5.094

A Novel Heterozygous L1453P Mutation in the MYH7 Gene Resulting in Laing Distal Myopathy in an Irish Family  Stela Lefter, Orla Hardiman, Russell McLaughlin, Sinead Murphy, Michael Farrell, Aisling Ryan

P5.101 Intraoperative

Neurophysiologic Monitoring with Hoffman Reflex During Thoracic Spine Surgery: A Lesson from a Series of 18 Patients  Anteneh Feyissa, Robert Smith, Sudhakar Tummala

P5.102

Motor Evoked Potentials From Multiple Recording Sites of the Lower Limbs as a Monitoring Tool of Central Motor Function  Walter Troni, Antonio Bertolotto, Federica Melillo, Simona Malucchi, Paola Berchialla, Francesca Sperli, Alessia Di Sapio

P5.103

Electrophysiological Findings in Acute Solanum Torvum Toxicity Robert Glover, Daniel Patterson, Nichloas Connors, Silas Smith, Mark Milstein, Michael Swerdlow

P5.104

The Pain of Anticipation: Differences Between Expected and Experienced Pain in Electrodiagnostic Testing  John Barghols, Samiullah Kundi, David Thompson, Eduardo De Sousa, Calin Prodan

P5.105

Levodopa Responsiveness of Blink Reflex Recovery Index: An Objective Method of Differenting Parkinson Disease from Parkinson Plus Syndromes Chandana Gaddipati, Meenakshisundaram Umaiorubahan

P5.106

Frequency of Radiculopathy in Patients with Carpal Tunnel Syndrome and Paracervical Pain  Rocio Garcia Santibanez, Nabil Altememi, Stephen Scelsa

2O14 Scientific Abstract Listing and Annual Meeting Information

P5.111

Cocaine and Ischemic Stroke: Epidemiological and Clinical Characteristics  Anand Vaishnav, Kerri Remmel, Kari Moore, Craig Ziegler

P5.112

Incidence and Mortality of Ischemic Stroke Subtypes in Joinville, Brazil: A Population-Based Study Marcos Lange, Norberto Cabral, Carla Moro, Alexandre Longo, Anderson Goncalves, Viviane Zetola, Tatjana Rundek

P5.114

Incident Cancer in Stroke Survivors: Analysis of the Vitamin Intervention for Stroke Prevention (VISP) Trial  Muhammad Suri, Malik Adil, Gustavo Rodriguez, Saqib Chaudhry, Adnan Qureshi

P5.115

Time Trends in Transient Ischemic Attack Admission from the Emergency Department  Karen Albright, John Donnelly, Michael Mullen, Brett Cucchiara, Justin Blackburn, Alexander Lo

P5.116

Temporal Trends in Hospitalization for Transient Ischemic Attack in the United States, 20002010  May Kim-Tenser, Lucas Ramirez, Natalie Valle, Steven Cen, William Mack, Nerses Sanossian, Amy Towfighi

P5.117

Education Status and Ischemic Stroke in Young: A Potential Target Towards Future Population Based Preventive Strategies.  Anand Vaishnav, Radhika Vaishnav

P5.118

Which Metabolic Syndrome Criteria Is More Relevant for the Prediction of Silent Brain Infarction? A Study in a Korean Population  Yong Bum Kim, PilWook Chung

P5.119

Neurology House Staff Experience Doesn’t Affect Acute Stroke Treatment  Gonzalez Castellon Marco, Joshua Stillman, Mitchell Elkind, Randolph Marshall, Joshua Willey

Poster Session V

P5.120

“On-the-job” Fatal Cardiovascular Events: Analysis of National Institute for Occupational Safety and Health Data  Amna Zarar, Aveen Saed, Nudrat Tasneem, Malik Adil, Adnan Qureshi

Cerebrovascular Disease and Interventional Neurology: Intracranial Aneurysms and Subarachnoid Hemorrhage P5.121 Thromboelastography

Determines a Transient Late Hypercoagulable State After Aneurysmal Subarachnoid Hemorrhage Preethi Ramchand, S Frangos, F Quattrone, S Doerfler, K Nawalinski, B Michel, C Ju, S Nyirjesy, N Driscoll, E Maloney-Wilensky, D Sandsmark, Michael Mullen, M Smith, B Pukenas, E Zager, S Stein, Scott Kasner, Joshua Levine, Monisha Kumar

P5.122

Inflammation, Nutritional Status and Outcome after Aneurysmal Subarachnoid Hemorrhage Neeraj Badjatia, Aimee Monahan, Amanda Carpenter, Laura Friedman, Jacqueline Zimmerman, J. Michael Schmidt, Jan Claassen, Kiwon Lee, E. Sander Connolly, Stephan Mayer, Wahida Karmally, David Seres

P5.123

THE VASOGRADE—A Simple, Reliable Grading Scale for Aneurysmal Subarachnoid Hemorrhage Airton Leonardo de Oliveira Manoel, David Turkel-Parrella, Ekaterina Kouzmina, Simon Abrahamson, Thomas Marotta, Tom Schweizer, Julian Spears, Loch MacDonald

P5.124

Clinical Outcomes After High-Grade Aneurysmal Subarachnoid Hemorrhage  Airton Leonardo de Oliveira Manoel, David Turkel-Parrella, Alberto Goffi, Victoria McCredie, David Ben-Israel, Ekaterina Kouzmina, Julian Spears, Thomas Marotta, Simon Abrahamson

P5.125

Headaches Following Endovascular Treatment of Cerebral Aneurysms: Coil Embolization Versus Flow Diversion  Martin Ollenschleger, Michael Mancini, Stephen Ohki, Gary Spiegel

P5.126

Rebleeding of a Cerebral Aneurysm During Transcranial Doppler: Hemodynamic Changes and Response to Treatment  Eric Marrotte, Tamer Abdelhak, Leonard Melvin, Panayiotis Varelas

P5.127

Extensive Proximal Migration of Posterior Communicating Artery Aneurysm Coil Presenting with a Transient Ischemic Attack  Ahmed Itrat, Esteban Cheng-Ching, Muhammad Hussain

P5.128

Utilization and Outcomes of Ventriculostomy in Non-traumatic Subarachnoid Hemorrhage During Last Decade in United States  Yogesh Moradiya, Santosh Murthy, Shreyansh Shah, Sneha Modi

P5.129

New Risk Score Improves Vasospasm Prediction following Subarachnoid Hemorrhage Using Markers of Vascular Compliance  Aashish Anand, Haitham Hussein, Mustapha Ezzeddine, Joseph Kass, Jose Suarez

P5.130

Long Term Survival and Hospital Re-admission Rates in Elderly Patients with Subarachnoid Hemorrhage Treated with Surgical or Endovascular Treatment  Saqib Chaudry, Mohammad Afzal, Alexanderos L. Georgiadis, Adnan Qureshi

P5.142

Validation of ICH and ICH-GS Scores in an Indian Cohort of Patients with Intracerebral Hemorrhage Treated Medically and with Surgical Interventions  Rohit Bhatia, V Sreenivas, Shaily Singh, M. v Padma, Kameshwar Prasad

P5.143

Spontaneous Spine Epidural Hematoma Is Most Frequently Idiopathic in Cause  Michael Pizzi, Scott Silliman

Predictors of the CT Angiography Spot Sign in Deep and Lobar Intracerebral Hemorrhage Farid Radmanesh, Guido Falcone, Christopher Anderson, Thomas Battey, Alison Ayres, Anastasia Vashkevich, Kristin Schwab, Javier Romero, Anand Viswanathan, Steven Greenberg, Joshua Goldstein, Jonathan Rosand, H. Bart Brouwers

P5.132

P5.144

Cerebrovascular Disease and Interventional Neurology: Intracerebral Hemorrhage and Other Hemorrhages P5.131

Spinal Epidural Hematoma in a Patient with Repair of Aortic Coarctation  Imad Khan, Neha Mirchandani, Laura Donarummo

P5.133

Cervico-Dorsal Intramedullary Hematoma in a Patient with Pompe Disease  Diego Nadile, Maria Gonzalez Toledo, Agustina Tamargo, Fatima Pagani Cassara, Alejandro Thomson, Francisco Muñoz, Francisco Klein

Development of PeriHematomal Edema Measurements in Intracerebral Hemorrhage Sebastian Urday, Lauren Beslow, David Asuzu, Anastasia Vashkevich, Alison Ayres, Thomas Battey, Magdy Selim, Jonathan Rosand, William Kimberly, Kevin Sheth

P5.145

P5.134

Intracerebral Hemorrhage Associated with Dietary Supplement Containing DMAA  Janet Elgallab, Robert Glover, Deepa Bhupali, David Gordon, Kathryn Kirchoff-Torres

The Impact on Radiology Utilization of Disseminating an Analysis on the Value of Neuroimaging Studies in Intracerebral Hemorrhage: The University Hospitals Case Medical Center Comprehensive Stroke Center Experience  Tanzila Shams, LeighAnne McCartney, Polly Westerberg, Cathy Sila

P5.135

P5.146

Lone Intraventricular Hemorrhage and Intraventricular Hemorrhage Associated with Small Parenchymal Component: Two Different Clinical Entities  Ather Taqui, Lauren Koffman, Muhammad Hussain, Ken Uchino

Etiologies of Intracerebral Hemorrhages from 2009-2012 at Mayo Clinic-Rochester  James Klaas, Sherri Braksick, Robert Brown, Alejandro Rabinstein, Jennifer Fugate

P5.153

Clinical Profile of Longitudinally Extensive Transverse Myelitis in Indian Population: A Prospective Study from a Tertiary Teaching Hospital of South India  Dhairyawan Pokalkar, Veena Narisetty, Murali Chekuri, Sowjanya Poosarla, Srilatha Sripuram, Sateesh Kumar Kamera

P5.154

Common Comorbidities Among Multiple Sclerosis Patients in the United States: An Analysis of In-patient Hospitalizations  Anthony Asemota, Han Wang, Shalini Selvarajah, Xuan Hui, Eric Schneider, Arun Venkatesan

P5.155

Demographics and Clinical Characteristics of Multiple Sclerosis in Kuwait: An Analysis of the National MS Registry  Raed Alroughani, S Ahmed, Jassem Al Hashel

P5.156

Familial Multiple Sclerosis Recurrence Risk in Argentina Francisco Varela, Mauricio Farez, María Balbuena Aguirre, Vanesa Nagel, Alejandro Köhler, Jorge Correale

P5.157

Excess Mortality in Multiple Sclerosis: A Meta-Analysis of Incidence and Standardized Mortality Rates Radu Tanasescu, Cris Constantinescu, Christopher Tench, Ali Manouchehrinia

P5.158

Sociocultural and Demographic Risk Factors for the Development of Multiple Sclerosis in Kuwait  Suhail Al-Shammri, Arpita Chattopadhyay, Magdy Girgis, Reema Mathew, Chetana Madala, Abayomi Akanji

P5.147

Fever and Transient Neurologic Worsening in Intracerebral Hemorrhage  Matthew Maas, Michael Berman, James Guth, Eric Liotta, Shyam Prabhakaran, Andrew Naidech

P5.159

Role of Magnetic Resonance Imaging in Non-Lobar Hypertensive Intracerebral Hemorrhage  Amir Adeli, Reza Behrouz

P5.137

P5.148

CNS Diseases and Differential Diagnosis

P5.136

Type of Substance Use Predicts Hemorrhage Versus Ischemia  Emma Kaplan, Rebecca Gottesman, Rafael Llinas, Elisabeth Marsh

P5.138

Intracerebral Hemorrhage Associated with Oral Phenylephrine Use  Brian Tark, Steven Messe, Clotilde Balucani, Steven Levine

P5.139

Reversible Cerebral Vasoconstriction Syndrome Presenting as Coital Headache and Intracerebral Hemorrhage  Alex Linn, Nancy Rosales, Camilo Garcia-Gracia, Efrain Salgado

P5.140

Direct Thrombin Inhibitors May Have a Decreased Risk of Intracerebral Hemorrhage Compared with Older Anticoagulants  Sindhu Ravipati, Daniel Woo, Padmini Sekar, Charles Moomaw, Matthew Flaherty, Jennifer Osborne

Cerebrovascular Disease and Interventional Neurology: Intracerebral Hemorrhage P5.141

Assessing the Safety and Cost-Effectiveness of Admission of Patients with Intracerebral Hemorrhage (ICH) to a Neurovascular Step Down Unit. Shaheryar Hafeez, Reza Behrouz



Intracerebral Hemorrhage Transfer Rates from U.S. Emergency Departments: Findings from the National Hospital Ambulatory Medical Care Survey  John Donnelly, Michael Mullen, Karen Albright, Justin Blackburn, Brett Cucchiara, Alexander Lo

P5.149

Primary Intraventricular Hemorrhage: A Review with Focus on Diagnostic Testing and Etiologies Ather Taqui, Lauren Koffman, Muhammad Hussain, Ken Uchino

P5.150

Yield of Follow-Up Imaging in Workup of Intracerebral Hemorrhage—a Retrospective Chart Review Clifford Meyers, Adam Kelly

MS and CNS Inflammatory Disease: Epidemiology P5.151

Clinical and Demographic Profile of Multiple Sclerosis Patients in India: Registry database of MS patients from All India Institute of Medical Sciences(AIIMS), New Delhi  Ankit Singhal, Rohit Bhatia

P5.152

Unveiling Multiple Sclerosis in Nigeria: The Conundrum of Diagnosis and Access to Disease Modifying Therapies  Njideka Okubadejo, Oluwadamilola Ojo, Temitope Lawal, Francis Ojini, Mustapha Danesi

The Diagnosis of Multiple Sclerosis in Hispanics Occurs Sooner in the Young Than in Adults  Megan Langille, Lilyana Amezcua, Margaret Burnett, Jose Aparicio, Wendy Mitchell

P5.160

Clinical and Immunological Features of Hashimoto’s Encephalopathy Presenting with Limbic Symptoms Akiko Matsunaga, Toru Kishitani, Tomoko Muramatsu, Tomomi Kame, Masamichi Ikawa, Osamu Yamamura, Tadanori Hamano, Yasunari Nakamoto, Makoto Yoneda

P5.161

Susac’s Syndrome in a 25-year-old Pregnant Woman Yasemin Tashman

P5.162

Postcontrast T2-FLAIR: a Useful Tool for Diagnosing and Monitoring Susac Syndrome  Irene Cortese, Govind Nair, Joan Ohayon, Luisa Vuolo, Martina Absinta, Pascal Sati, Bibiana Bielekova, Daniel Reich

P5.163

MRI in Susac’s Syndrome: A Propos of the Barkhof-Tintore Criteria  Sreekanth Koneru, Neil Jouvenat, Kathleen Healey, Rana Zabad

P5.164

Long Segment Spinal Cord Involvement as the Initial Clinical Manifestation of Sarcoidosis Jamie Adams, Steven Galetta

Fast, Easy Registration Online  ·  AAN.com/view/AM14

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Wednesday April 30



First Authors stand by Posters from 5:00 p.m.–6:30 p.m.



Wednesday, April 30 P5.165

IgG4-Related Disease Manifesting as Middle Cranial Fossa Mass: A Case Report  Prerna Malla, Joseph Zachariah, Bashar Katirji

P5.166

Catatonia: a Duel of Hashimoto’s Encephalopathy and Anti NMDA Receptor Encephalitis Elena Grebenciucova

P5.167

Clinical Manifestations, Imaging Findings, and Immunomodulatory Therapeutic Strategies for Three Patients with Concurrent Stiff Person Syndrome and Cerebellar Ataxia Due to Anti-GAD Antibodies: A Case Series  Lauren DeNiro, Jerome Graber, Howard Geyer, Alexis Boro

P5.168

Association of Parenchymal and Vascular Damage (Mixed Pattern) in Neurobehçet: A Case Series Study  Youness Habtany, Fatima Dany, Nada Benkirane, Bouchra El Moutawakil, Mohamed Abdoh Rafai, Ilham Slassi

P5.169

A Rare Autoimmune Encephalitis—Due to DipeptidylPeptidase-like Protein-6 (DPPX) Autoantibody; A Case Report Shawna Suchecki, Laura Risley, Earl Zimmerman, Eric Molho, Era Hanspal, Josep Dalmau

P5.170

Cytokine Disarrangement and Increased Soluble Amyloid A (SAA) in Cerebrospinal Fluid (CSF) of Patients with Neurosarcoidosis (NS)  Maria ReyesMantilla, Anupama Kumar, Jorjetta Ilieva, Carlos Pardo-Villamizar

P5.171

Common Variable Immunodeficiency Mimicking Neurosarcoidosis  Konark Malhotra, Santosh Ramanathan, Deeksha Agrawal, Sandeep Rana, Thomas Scott

P5.172

Primary Central Nervous System Lymphoma Mimicking Multiple Sclerosis with Spontaneously Remitting Lesions  Erin Longbrake, Robert Schmidt, Anne Cross, Enrique Alvarez

P5.173 Leukoencephalopathy

Associated with Levamisole Toxicity from Cocaine Use  Nicky Sheldon, Bridget Bagert

P5.174

Hematopoietic Stem Cell Transplantation for Adult Cerebral X-linked Adrenoleukodystrophy  Wolfgang Köhler, Jörn-Sven Kühl

P5.175

Monoclonal B Cell Population in a Patient with Neurosarcoidosis Justine Brink

P5.176

TWEAK Stimulation of Microglia and Implications for Neuropsychiatric Lupus  Ariel Stock, Chaim Putterman

P5.177

Distinguishing ClinicoRadiological Features in Patients with Central Nervous System Tumefactive White Matter Lesions  Xuling Lin, Kevin Tan, Lishya Liauw, Aung Soe Tin, Weiling, Eileen Soon, Zhu Yin Shih, Raphael, Boon Ping Toe, Hwee Yee Lee, Wai-Yung Yu

P5.178

Memory Disturbance in the Mice Treated with Intraventricular Administration of CSF from NMDAREncephalitis Patients  Keiko Tanaka, Yongzhi Li, Nobuo Kato, Tsutomu Takegami

98

P5.179

Anti-NMDA Receptor Antibodies in Neurologic Disease Jessica Panzer, Bailey Baumann, Hiro Furukawa, Noriko Simorowski, Amy Gleichman, David Lynch

P5.180

Acute Transverse Myelitis: CSF Determinants in the Differential Diagnostics  Laura Kupila, Nina Jaakonmäki, Heini Huhtala, Laura Airas

P5.181

A Note of Caution About the Diagnosis and Treatment of Suspected Transverse Myelitis (TM)  Jorge Jimenez Arango, Maureen Mealy, Phillipe Gailloud, Carlos Pardo-Villamizar

P5.182

Contribution of Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) in Myelitis: A Multicentre Cohort of 13 Cases Jessica Orgeval, Denis Mariano Goulart, Laurent Collombier, Giovanni Castelnovo, Mahmoud Charif, Clarysse Carra, Xavier Ayrignac, Nicolas Gaillard, Mohamed Chbicheb, Dimitri Renard, Guillaume Taieb, Eric Thouvenot, Astrid Corlobe, Nicolas Champfleur, Pierre Labauge

P5.183

3:00 p.m.–6:30 p.m. P5.191

Urinary Retention as the Presenting Symptom of West Nile Encephalitis: Report of Two Cases.  Rashedul Hasan, John DeToledo

P5.204

P5.192

Multiple Mothballs or Multiple Sclerosis: A Diagnostic Dilemma  Divyanshu Dubey, Vibhash Sharma, Olaf Stuve

P5.205

P5.193

P5.206

Magnetic Resonance Imaging Changes After Plasma Exchange Treatment in Steroid-Refractory Relapses in Multiple Sclerosis and Other CNS Idiopathic Inflammatory Demyelinating Diseases.  Jose Meca-Lallana, Rocio Hernandez Clares, Ester Carreon Guarnizo, Adelaida Leon Hernandez, Begoña Palazon Cabanes, Gema Salgado Cecilia, Encarna Andreu Reinon, Judith Jimenez Veiga, Margarita Cacho Perez, Guadalupe Ruiz Merino, Jose Javier Martin Fernandez

P5.194

Multiple Sclerosis Diagnosis: A Survey of Neurology Residents’ Knowledge on Current Diagnostic Criteria  Salim Chahin, Nikitha Ashok, Raymond Price, Clyde Markowitz

Cognitive Deficits, Cerebrospinal Fluid Pleocytosis and White Matter Lesions Following Parvovirus B19 Infection in an Immunocompetent Adult  Ariel Antezana, Joseph Herbert, Ilya Kister

P5.195

P5.184

P5.196

The Specificity of CSF B Cell Reactivity in HTLV-1 Associated Myelopathy  Jerry Lin, Alexandra Berman, Christopher Sears, Saud Sadiq

P5.185

Acute Disseminated Encephalomyelitis Following an Acute JC Virus Infection  Sean Rogers, Ramsey Falconer, Yasar Torres-Yaghi, Heather Boynton, Chris Sonne, Carlos Mora, Carmelo Tornatore

P5.186 Paraneoplastic

Myelopathy with Positive Antigolgi Autoantibody  YuanKai Lee, Sonia Kumari, Gordon Mazibrada

P5.187

N-methyl D-aspartate Receptors (NMDAR) Antibodies Associated with Distinct Clinico-Radiological White Matter Syndromes: Clinical Evidence for an Anti-NMDAR Leukoencephalopathy? Yael Hacohen, Michael Absoud, Cheryl Hemingway, Leslie Jacobson, Jean-Pierre Lin, Mike Pike, Sunil Pullaperuma, Ata Siddiqui, Evangeline Wassmer, Camila Buckley, Sarosh Irani, Angela Vincent, Ming Lim

P5.188

New Autoantibodies Against Neutral Glycolipids in Encephalomyeloradiculoneuropathy Tatsuro Mutoh, Sayuri Shima, Tomomasa Ishikawa, Akihiro Ueda, Kunihiko Asakura

P5.189

The Oxford Experience: Clinical Features and Outcomes of 25 NMDAR-Ab Positive Patients Including Those with Atypical Presentations Katrina Morris, Camilla Buckley, Belinda Lennox, Yael Hacohen, Ester Coutinho, Angela Vincent

P5.190

Clinical Features, Diagnostic Findings and Treatment of Susac Syndrome: A Case Series  Ivana Vodopivec, Sashank Prasad, Nagagopal Venna

Bradycardia Leading to Pacemaker Placement: A Characteristic Prodromal Syndrome of VGKCC/LGI1 Antibody Associated Encephalitis Georges Naasan, Sarosh Irani, Brianne Bettcher, Michael Geschwind, Jeffrey Gelfand MR Imaging Trailing Clinical Expression of Natalizumab-Associated PML in Multiple Sclerosis: A Rare But Serious Diagnostic and Management Problem  Christopher Muth, Christian Hernandez, Dusan Stefoski, Roumen Balabanov, Michael Ko

P5.197

Predominantly Spinal Phenotype of Relapsing-Remitting Multiple Sclerosis  Jacob Cogan, Nataliya Ternopolska, Wendy Vargas, Susan Gauthier, Nancy Nealon, Timothy Vartanian, Jai Perumal

Headache: Epidemiology P5.198

Headache in Service Members Deployed to Afghanistan  Richard Young, Michael Myslenski, Peter Petrillo

P5.199

Distinctive Anatomical and Physiological Features of Migraine Aura Revealed by 18 Years of Recording. Jakob Hansen, Serapio Baca, Andrew Charles

P5.200

Chiari Headache Mechanisms: The Role of Neck Spasm and Migraine  Fredric Cantor, Jessica Mack, John Heiss

P5.201 WITHDRAWN P5.202

Developing and Validating the ID-Chronic Migraine (ID-CM) Screening Tool  Richard Lipton, Daniel Serrano, Andrew Blumenfeld, David Dodick, Sheena Aurora, Werner Becker, H. Diener, ShuuJiun Wang, Maurice Vincent, Dawn Buse, Joanna Sanderson, Sepideh Varon, Michael Reed

P5.203

No Laughing Matter: A Case of Gelastic Migraine  Paul Mathew, Carrie Robertson

2O14 Scientific Abstract Listing and Annual Meeting Information

A Closer Look at the Patients Who Present to the Emergency Department with Headache  Mia Minen, Benjamin Friedman The Case of Migraine with Visual and Olfactory Hallucination Related to Food Allergy  Vladimir Klinov, Larisa Syrow Multifocal Multiform Nummular Headache (NH): A Case Report  Stephanie Goldberg, Sarah Vollbracht, Brian Grosberg

P5.207

Peripartum Pneumocephalus Associated with Epidural Anesthesia for Labor  Sudama Reddi, Valentyna Honchar, Matthew Robbins

Aging, Dementia, and Cognitive and Behavioral Neurology: Epidemiology P5.208

Learning from our Mistakes: APOE4 Influences Misdiagnosis of Alzheimer’s Disease and Frontotemporal Degeneration  Jenna Haley, Corey McMillan, David Irwin, Beth McCarty Wood, Katya Rascovsky, David Wolk, John Trojanowski, Leslie Shaw, Vivianna Van Deerlin, Murray Grossman

P5.209

Epidemiology of Tandem Gait Abnormalities in Aging  Ilya Bragin, Vijayaleskhmi Nair, Joe Verghese

P5.210

Risk Factors for Cognitive Change in Patients with Dementia Due to Alzheimer’s Disease  Fabricio Oliveira, Paulo Bertolucci, Marilia Smith, Elizabeth Chen

P5.211

Prevalence, Incidence, and Associations between APOE Genotype, Cardiovascular Risk Factor, and Dementia in Cuban Populations  Jorge Jesús Llibre Guerra, Milagros Guerra, Juan Carlos Llibre Guerra, Juan Jesús Llibre Rodriguéz

P5.212

Cardiac Function and the Risk of Dementia  Renée de Bruijn, Maarten Leening, Oscar Franco, Albert Hofman, Peter Koudstaal, Mohammad Ikram

P5.213

Long-term Mortality in Incident MCI Subtypes. Data from the NEDICES Cohort  Félix Bermejo-Pareja, Alvaro Sánchez-Ferro, Israel Contador Castillo, Elina Boycheva, Rocio Trincado, Sara Llamas, Alejandro Herrero, Fernando Sierra, Alberto Villarejo Galende, Julian Benito-Leon

P5.214 Plasma β-Amyloid and MRI

markers of Structural Brain Aging Sara Kaffashian, Christophe Tzourio, Aicha Soumare, Carole Dufouil, Bernard Mazoyer, Susanna Schraen-Maschke, Luc Buee, Stephanie Debette

P5.215

Comparing Cognitive Screening Tools in a Rural Ecuadorian Population: The Atahualpa Project Clinton Wright, Hannah Gardener, Mauricio Zambrano, Victor Del Brutto, Oscar Del Brutto

Poster Session V

P5.216

Cognitive Impairment, Asymptomatic Carotid Stenosis and Arterial Hypertension in Adult Persons Without a History of Stroke: A PopulationBased Epidemiological Study Petya Mineva, Dimitar Talalaev, Valentin Proychev

Aging, Dementia, and Cognitive and Behavioral Neurology: Cerebrovascular Ischemia, Metabolism, and Epidemiology P5.217

Cognitive Enhancer Based Treatment Outcome in Mild to Moderate Alzheimer’s Disease Is Modulated by Severity of White Matter Hyperintensity  Kok Pin Ng, Aloysius Ng, Nagaendran Kandiah

P5.218

Clinical Predictors of a Higher Cerebrovascular Burden in Dementia: A Clinicopathological Study.  Solene Moulin, Julia Salleron, Gauthier Calais, Florence Pasquier, Vincent Deramecourt

P5.219

Food Insecurity Is Associated with Development of Faster Cognitive Decline in the Boston Puerto Rican Health Study  Janice Wong, Tammy Scott, Yinge Li, Katherine Tucker, Xiang Gao

P5.220

Silent Cerebral Ischemia Is Highly Prevalent in AD and Is Independently Associated with Medial Temporal Atrophy  Nagaendran Kandiah, Russell Chander, Aloysius Ng, Pryseley Assam

P5.221

Effectiveness of Cognitive Enhancers in Alzheimer’s Disease with Concomitant Small Vessel Cerebrovascular Disease.  Kok Pin Ng, A Ng, E Heng, S Huang, P Assam, Nagaendran Kandiah

P5.222

Burden of Silent Cerebrovascular Disease and Not Acute Infarct Characteristics Determine PostStroke Cognitive Impairment, Both in Small Vessel and Large Vessel Strokes Yen Yeong Poh, Yun Qi Josephine Poh, Aloysius Ng, Maznah Marmin, Yee Lean Ho, Hani Zainal, Nagaendran Kandiah

P5.223

Pharmacogenetics of Lipid Metabolism Modulators in Patients with Dementia Due to Alzheimer’s Disease  Fabricio De Oliveira, Paulo Bertolucci, Marilia Smith, Elizabeth Chen

P5.224

Evidence on Diet Modification for Alzheimer’s Disease and Mild Cognitive Impairment  Hilary Glazer, Christine Greer, Dulce Barrios, Christopher Ochner, James Galvin, Richard Isaacson

P5.225

Dementia: An Emerging Field in Pakistan  Quratulain Khan

P5.226

Forgetful But Not Disabled: Predictors of Incident IADL Limitations  Pamela Rist, Jessica Marden, Benjamin Capistrant, Qiong Wu, M. Maria Glymour

Aging, Dementia, and Cognitive and Behavioral Neurology: Creutzfeldt-Jakob Disease and Subacute Encephalopathies P5.227

A Case of Refractory Hashimoto’s Encephalopathy Demonstrating Improvement with Plasmapheresis  Sarah Nelson, Yasir Jassam, Lynne Taylor

P5.228

Voltage Gated Calcium Channels Antibody-associated Autoimmune Encephalitis Abdulrahman Alwaki, Anibal Lugo, Christopher Goshgarian, Omar Ahmad, Hebah Hefzy, Panayiotis Mitsias

P5.229

Hashimoto Encephalopathy: A Study of Clinical Profile, Radiological and Electrophysiological Correlation in a Tertiary Care Centre in South India  Rangasetty Srinivasa, Surya Sharma, J.v. Mahendra, Rohan. Mahale, Madhusudhan B.K

P5.230

Reversible Dementia with Myoclonus due to Concurrent HSV-2 and Syphilis Central Nervous System Infection in an Immunocompetent Man. Liliana Robles, Aashish Anand, Joseph Kass

P5.238

Paired Comparison Study Distinguishing Parkinsonian Dementia Syndromes from Parkinson’s Disease  Douglas Scharre, Shu-Ing Chang, Haikady Nagaraja, Ariane Park, Punit Agrawal, Anahita Adeli, Shannon Linder, Anne Kloos, Deborah Kegelmeyer, Nora Fritz, Maria Kataki

P5.239

Education Effects on Rate of Cognitive Decline Compared in Autopsy Confirmed Alzheimer’s, Lewy Body and Vascular Dementia  Lyla Mourany, Jagan Pillai

P5.240

Cognitive and Behavioral Changes in PSP: Comparison of PSPParkinsonism with PSP-Richardson Syndrome  Saria Refai, Linda Hershey, David Thompson, Jennifer Lippoldt

P5.241

Direction of Finger Displacement in Parkinson Disease (PD) May Predict the Onset of Dementia Aman Deep, Abraham Lieberman, Rohit Dhall, An Tran, Ming-Jai Liu, Kamala Saha, Naomi Salins, Arshia Sadreddin, Guillermo Moguel-Cobos, John Karis, Narayanan Krishnamurthi

P5.242

Presence of Voltage-gated Potassium Channel (VGKC)-complex Antibody in a Case of Genetic Prion Disease  Adham Jammoul, Richard Lederman, Jinny Tavee, Yuebing Li

Transcranial Sonography(TCS) in Lewy Body Disease (LBD) Versus Other Dementia. Correlation with Clinical Symptoms.  Maria Fernandez, Nuria Campora, Waleska Berrios, Juan Ignacio Rojas, Jorge Norscini, Edgardo Cristiano, Angel Golimstok

P5.232

P5.243

P5.231

Creutzfeldt-Jakob Disease with Unusual Finding of Significant CSF Pleocytosis  Pawan Rawal, Drew Uhrig, Leonardo Almeida, Hassan FathallahShaykh

P5.233

Hyperacusis as the Initial Presentation of Creutzfeldt-Jakob Disease  Alexander Merkler, Joseph Safdieh

P5.234

Increased Interleukin-17 in the Cerebrospinal Fluid in Sporadic CreutzfeldtJakob Disease  Koji Fujita, Naoko Matsui, Yukitoshi Takahashi, Yasushi Iwasaki, Mari Yoshida, Tatsuhiko Yuasa, Yuishin Izumi, Ryuji Kaji

P5.235

Wernicke-Korsakoff Syndrome Mimicking Sporadic Jakob-Creutzfeldt Disease  Serggio Lanata, Pierluigi Gambetti, Michael Geschwind

P5.236

Novel Pomegranate Oil NanoEmulsions for the Prevention and Treatment of Neurodegenerative Diseases: The Case of Genetic CJD  Ruth Gabizon, Michal Mizrahi, Yael Friedman-Levy, Liraz Larush, Kati Frid, Orli Binyamin, Nina Feinstein, Dvir Dori, Haim Ovadia, Tamir Ben-Hur, Shlomo Magdassi

Aging, Dementia, and Cognitive and Behavioral Neurology: Behavioral Neurology of Movement Disorders P5.237

Environmental Predictors of Cognitive Impairment in Parkinson’s Disease  Anna Blanken, Mona Beyer, OleBjorn Tysnes, Guido Alves, Jan Larsen, Liana Apostolova



Simple Motor Stereotypies Are Not Specific Core Features of Behavioral Frontotemporal Dementia Sara Pompanin, Chiara Formentin, Zarantonello Giulia, Nela Jelcic, Giacomo Rolma, Matteo Tagliapietra, Giovanni Zorzi, Annachiara Cagnin

P5.244

Modulation of FeedbackRelated Negativity During Trial-and-error Task in Parkinson Disease: Assessing the Role of Apathy and Depression in Cognitive Deficits  René Quilodran, Laura Viñales, Alex Araneda, Irving Santos, Francisco Castilla

P5.245

Focused Ultrasound Thalamotomy Modulates Inhibitory Motor Control in Essential Tremor  Scott Sperling, Carol Manning, W. Jeffrey Elias, Scott Wylie

P5.246

A Common Movement Abnormality in Patients with LGI1 Limbic Encephalitis Is a Manifestation of Tonic Seizures.  Danielle Andrade, Peter Tai, Josep Dalmau, Richard Wennberg

Movement Disorders: Atypical Parkinsonism P5.247

Clinical Features of Patients with Concomitant Parkinson’s Disease and Progressive Supranuclear Palsy Pathology  Heather Rigby, Brittany Dugger, Charles Adler, Thomas Beach, Holly Shill, Erika Driver-Dunckley, Marwan Sabbagh, Lucia Sue, John Caviness

P5.248

Three Sib-Pairs of AutopsyConfirmed Progressive Supranuclear Palsy  Shinsuke Fujioka, Monica Sanchez Contreras, Audrey Strongosky, Kotaro Ogaki, Nathaniel Whaley, Pawel Tacik, Jay Van Gerpen, Ryan Uitti, Owen Ross, Zbigniew Wszolek, Rosa Rademakers, Dennis Dickson

P5.249

Mutational Analysis of COQ2 in Italian Patients with MSA  Dario Ronchi, Sara Bonato, Ernesto Di Biase, Valentina Melzi, Ilaria Trezzi, Stefania Corti, Nereo Bresolin, Giacomo Comi, Alessio Di Fonzo

P5.250

Hypercapnic Respiratory Failure Is Often Seen in Advanced Progressive Supranuclear Palsy Nobu Komai, Chiho Ishida, Kazuya Takahashi, Atsuro Tagami

P5.251

FDG-PET in Pathologically Confirmed 4R-Tauopathy Variants Nicholas Zalewski, Hugo Botha, Jennifer Whitwell, Val Lowe, Dennis Dickson, Keith Josephs

P5.252

Human Mirror Neuron System Is the Anatomical Substrate for Imitation Apraxia in Corticobasal Syndrome: (18F)FDG PET and MRI studies  HyukJun Yoon, Seok Min Kim, Hyuk Jin Yun, Kyung A Kim, Doris Doudet, Jong-Min Lee, Chong S Lee

P5.253

Do Autonomic Studies Help Differentiate Multiple System Atrophy from PD with Dysautonomia in Clinical Practice?  Aashoo Mentreddi, Svjetlana Miocinovic, Pravin Khemani, Steven Vernino, Srikanth Muppidi

P5.254

Atypical Parkinsonism Following Occult Carbon Monoxide Exposure  Shruti Raja, Tara Dutta, Justin Kwan

P5.255

A Case of Klinefelter Syndrome Associated with Parkinsonism  Lourdes Lago, Henry Moore, Carlos Singer

Movement Disorders: Cognition and Parkinson’s Disease P5.256

Which Cognitive Subdomain Is Related with Motor Symptoms in the Early Stage of Parkinson’s Disease?  Minjik Kim

P5.257

Hallucinations and Dementia in Parkinson’s Disease: Clinically Related But Structurally Distinct  Jennifer Goldman, Glenn Stebbins, Doug Merkitch, Vy Dinh, Bryan Bernard, Leyla DeToledo-Morrell, Christopher Goetz

P5.258

What Level of Parkinson’s Disease Severity Is Associated with Significant Differences in Cognitive Function?  Christian Lachner, Melissa Armstrong, Ann Gruber-Baldini, Erik Barr, Paul Fishman, Stephen Reich, William Weiner, Lisa Shulman

P5.259

Association of Cognitive Screening Tests with Disability in Parkinson’s Disease  Melissa Armstrong, Erik Barr, Ann Gruber-Baldini, Stephen Reich, Christian Lachner, Paul Fishman, Lisa Shulman

Fast, Easy Registration Online  ·  AAN.com/view/AM14

99

Wednesday April 30



First Authors stand by Posters from 5:00 p.m.–6:30 p.m.



Wednesday, April 30 P5.260

Long-term Outcomes of Parkinson’s Disease Patients with Normal Cognition.  Kara Pigott, Jacqueline Rick, Howard Hurtig, Alice Chen-Plotkin, John Duda, James Morley, Lama Chahine, Nabila Dahodwala, Jori Fleisher, Rizwan Akhtar, Andrew Siderowf, Rachel Goldmann Gross, Sharon Xie, John Trojanowski, Daniel Weintraub

P5.261

Parkinson’s Disease Patients with Mild Cognitive Impairment do Not Have Increased Brain Iron Concentrations as Compared to Patients Without Cognitive Impairment  Jesper Hagemeier, Thomas Guttuso, Niels Bergsland, Mari HeininenBrown, Ellen Carl, David Lichter, Robert Zivadinov

P5.262

Cognitive Deficits in Veterans with Parkinson’s Disease: A National Database Analysis  Brandon Barton, Zhiping Huo, Sandra Kletzel, Kevin Stroupe, Christopher Goetz, Frances Weaver

P5.263

Cholinesterase Inhibitors for Cognitive Impairment in Patients with Parkinson’s Disease: A MetaAnalysis  Gennaro Pagano, Giuseppe Rengo, Michele Tagliati

P5.264

Parkinson’s Disease Motor Phenotype Predicts Cognitive Performance  David Isaacs, Joshua Herb, Nelleke Van Wouwe, Daniel Claassen

P5.265

Lower Education Status Associates with Axial Motor Burden in Parkinson Disease  Vikas Kotagal, Roger Albin, Martijn Muller, Robert Koeppe, Kirk Frey, Nicolaas Bohnen

Movement Disorders: Sleep and Movement Disorders and Miscellaneous Diagnoses P5.266

Restless Limbs Syndrome (RLS) Presenting as Hemisyndrome: A Case of Dejerine-Roussy Syndrome Responsive to Dopamine Agonists  David Dickoff

P5.267

Restless Limb Syndrome (R.L.S.): The Real Patient Experience. David Dickoff, Stephanie Dontje

P5.268

Effect of Rotigotine Transdermal System on Nocturnal Blood Pressure Changes Associated with Periodic Limb Movements During Sleep in Patients with Restless Legs Syndrome Wolfgang Oertel, Axel Bauer, Werner Cassel, David Rye, Arthur Walters, John Winkelman, Lars Bauer, Lars Joeres, Frank Grieger, Kimberly Moran, Erwin Schollmayer, John Whitesides, Claudia Trenkwalder

P5.269

Extrapontine Myelinolysis Presenting as L-DOPA-Unresponsive Parkinsonism  Nicolaas Anderson, Akshay Shah

P5.270

Effect of IVIg on GAD Epitopes in Patients with Stiff-Person Syndrome: Implications for Other Antibody-Mediated Neurological Disorders Responding to IVIg  Penelope Fouka, Harry Alexopoulos, Panagiotis Politis, Marinos Dalakas

P5.271

Movement Disorders in Chronic Regional Pain Syndrome (CRPS)  Mitesh Lotia, Kathrin LaFaver

100

P5.272

Hyperactivity and Obsessive Compulsive Disorder: An Unusual Presentation in Perry Syndrome. A Clinicopathological Study. Guillaume Lamotte, Françoise Chapon, Gilles Defer

P5.273

Factors Influencing Medical Treatment of Parkinsonism with Conflicting DaT Imaging: The Cleveland Clinic Experience  Dimitrios Nacopoulos, Srivadee Oravivattanakul, Anwar Ahmed, Hubert Fernandez

P5.274

Dopaminergic Neurons Loss in Parkinson’s Disease: How Much Sex Hormones Decline Contribute to?  Mahmoud Elhusseiny, Mohamed Sarhan, Mohamed Salama, Mohamed Elgamal, Sherif Shawer, Ahmed Attia, Mohamed Sobh

P5.275

Investigating the Night to Night Variability of REM Without Atonia in Parkinson’s Disease  Samuel Bolitho, Sharon Naismith, Ron Grunstein, Zoe Terpening, Moran Gilat, Simon Lewis

Sleep: Sleep Related Breathing P5.276

Frequency and Causes of Discontinuation of Continuous Positive Airway Pressure Treatment in Multiple System Atrophy  Takayoshi Shimohata, Hideaki Nakayama, Masatoyo Nishizawa

P5.277

REM Sleep Rebound on a First CPAP Recovery Night in Severe Obstructive Sleep Apnea Patients  Raoul Biniaurishvili

P5.278

PAP Therapy Boosts REM Dependent Memory Consolidation for Perceptual Skill Learning in Patients with Obstructive Sleep Apnea.  Heidi Roth, Chayla Hart, David Sanders, Young Truong, Bradley Vaughn, Robert Stickgold

P5.279

Subjective Sleep Quality and Insomnia: Correlation with Cardiovascular Health Status in Community-Dwelling Elders Living in Rural Coastal Ecuador— The Atahualpa Project  Pablo Castillo, Oscar Del Brutto, Robertino Mera, Victor Del Brutto

P5.280

OSA Is Under-reported in Patients Admitted with Acute Stroke Scott Shorten, Richard Dubinsky

P5.281

A Pilot Study Identifying a Unique Pattern on the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) that Predicts Obstructive Sleep Apnea (OSA) in a Dementia Screening Setting  Amber Gerber, Donn Dexter

P5.282

A Novel Capability for Monitoring Cerebral and Systemic Hemodynamics, ECG and Actigraphy During Sleep  Vladimir Ivkovic, Gary Strangman, Quan Zhang

P5.283

Diagnostic Thresholds for Quantitative REM Sleep Muscle Densities, Phasic Burst Duration, and REM Atonia Index in REM Sleep Behavior Disorder with Co-morbid Obstructive Sleep Apnea Erik St. Louis, Stuart McCarter, Bradley Boeve, Michael Silber

3:00 p.m.–6:30 p.m. Sleep: Parasomnias and Measurement Technologies P5.284

Cortical Excitability Relation to Periodic Leg Movements (PLMS) and Sleep in Restless Legs Syndrome (RLS)  Rachel Marie Salas, Aadi Kalloo, Tiana Krum, Richard Allen

P5.285

Sleep Quality, Duration, Insomnia Symptoms, and Prevalence of Sleep Disordered Breathing in Parkinson’s Disease  Shirin Shafazand, Douglas Wallace, Silvia Vargas, Henry Moore, Corneliu Luca, Heather Katzen, Bonnie Levin, Carlos Singer

P5.286

Comparing Periodic Limb Movements in Sleep in Subjects with and Without Waking Paretic/Plegic Limbs  Mark Dyken, Miriam Zimmerman, Kyoungbin Im, Deborah Lin-Dyken, Christine Glenn, Mark Blumberg, Robert Rodnitzky, Greta Sokoloff

P5.287

Use of a Non-invasive Neurotechnology, HIRREM, Is Associated with Improved Sleep and Mood in a Heterogeneous Cohort.  Jared Cook, Catherine Tegeler, Sung Lee, Hossam Shaltout, Meghan Franco, Charles Tegeler

P5.288

Treatment of Restless Legs Syndrome (Willis-Ekbom Disease) with Rotigotine and Pramipexole.  Diego GarciaBorreguero, Melissa Sweeney

P5.289

The Effect of Prior Exposure to Dopamine Agonists (DA) on Response to Treatment with Gabapentin Enacarbil (GEn) in Adult Patients with Moderate-toSevere Primary Restless Legs Syndrome (RLS): Pooled Analyses from 3 Randomized Trials  William Ondo, Neal Hermanowicz, Diego García-Borreguero, Mark Jaros, Richard Kim, Gwendoline Shang

P5.290

The Efficacy of Gabapentin Enacarbil (GEn) in Adult Patients with Severe Primary Restless Legs Syndrome (RLS): Pooled Analyses from 3 Randomized Trials  Daniel Lee, William Ondo, Alon Avidan, Diego García-Borreguero, Mark Jaros, Richard Kim, Gwendoline Shang

P5.294

Kleine-Levin Syndrome with Rapid Cycling—Case Report and Review of the Literature  Claudio De Gusmao, Kiran Maski, David Urion

P5.295

Sleep Dependent Memory Consolidation in Children with Autism Spectrum Disorders  Kiran Maski, Hannah Holbrook, Dara Manoach, Ellen Hanson, Kush Kapur, Robert Stickgold

P5.296

Evaluation of the Effect of Modafinil on Cognitive Functions in Patients with Idiopathic Hypersomnia with P300  Mehmet Yaman, Fatıma Karakaya, Hasan Mayda, Ibrahim Guzel, Gokhan Koyuncu, Serdar Oruc

P5.297

Sleep and Sleep Disruption in Predator Odor Trauma Model of Posttraumatic Stress Disorder  Omar Taranissi, Rishi Sharma, Pradeep Sahota, Mahesh Thakkar

P5.298

Sudden Onset of Sleep Due to Bilateral Hypothalamic Lesions in Neuromyelitis Optica Spectrum Disorder Positive for Aquaporin 4 Antibody (AQP4)  Hidehiko Okuma, Yuki Hatanaka, Kuwabara Midori, Kanbayashi Takamichi, Masahiro Sonoo

Neuro Trauma, Critical Care, and Sports Neurology: Concussion P5.299

A Portable Non-invasive Biosensor Based Approach to Actively Assess Sports Concussion and Mild Traumatic Brain Injury  Adam Simon, Janet Van Gelder, Hashem Ashrafiuon, David Devilbiss

P5.300

Effect of Concussion and Blast Exposure on Clinical Symptoms Following Deployment of U.S. Military Personnel  Mikias Wolde, Briana Perry, Jay Haran, Justin Campbell, Alia Creason, Catalina Sher, Lauren Stentz, Jack Tsao

P5.301

Hyperglycemia and Leukocytosis as Predictors of Abnormal Head CT Following Concussion Aakash Bodhit, Yasamin Daneshvar, Pratik Patel, Keith Peters, Latha Ganti

P5.291

P5.302

Sleep: Intrinsic Disorders of Sleep

P5.303

Subjective Perception of Sleepiness in a Driving Simulator Is Different from Perception in the Maintenance of Wakefulness Test David Schreier, Corinne Roth, Johannes Mathis

P5.292

Energy Expenditure in Narcolepsy Patients and Controls Claire Donjacour, Paul Schoffelen, Sebastiaan Overeem, Gert Jan Lammers, Hanno Pijl, Klaas Westerterp

P5.293

Respiratory Safety of the Orexin Receptor Antagonist Suvorexant During Sleep in Patients with Compromised Respiratory Function and in Healthy Subjects  Matthew Troyer, Naoto Uemura, Jackie McCrea, John Palcza, Mardik Donikyan, Gary Zammit, Rong Liu, Tara Siringhaus, Janice Rowe, Deborah Card, Sabrina Marsilio, Timothy Grant, Russell Rosenberg, John Wagner, Hong Sun

2O14 Scientific Abstract Listing and Annual Meeting Information

Validation of a SelfAdministered iPad®- and iPod®-Based Tool for Assessing Information Processing  Andrew Russman, Joshua Hirsch, David Schindler, Daniel Burke, Susan Linder, Jay Alberts A Potential Biomarker in Sports-Related Concussion: Brain Functional Connectivity Alteration of the Default-mode Network Measured with Sequential Resting-state fMRI David Zhu, Tracey Covassin, Sally Nogle, Scarlett Doyle, Doozie Russell, Randolph Pearson, Jeffrey Monroe, Christine Liszewski, J DeMarco, David Kaufman

P5.304

Structural Imaging Correlations with Memory Assessment and Concussion in Retired NFL Athletes Kyle Womack, Jeremy Strain, Nyaz Didehbani, Heather Conover, Michael Kraut, Munro Cullum, John Hart

Poster Session V

P5.305

Atlanto-axial Subluxation: Treatable Cause of Post Concussion Syndrome  Kevin Crutchfield, Dennis Rivenburgh, Laura Morris, Jenna Werner

P5.317

P5.306

Prevalence of Sleep and Psychiatric Disorders in Patients Who Present to the Emergency Department with Concussion  Pratik Patel, Aakash Bodhit, Yasamin Daneshvar, Latha Ganti

P5.318

P5.307

P5.319

The King-Devick Test Is Vastly Superior to the Symbol Digit Modalities Test as a Sideline Determinant of Concussion in Mixed Martial Arts Fighters  Daniel Kantor

P5.308

Barriers to Recovery after Concussion  Teena Shetty, Kelianne Cummings, Christine Villegas, Erin Manning, Niesha Voigt, Maxwell Singer, Joseph Nguyen

P5.309

Post Concussion Delirium in Children: Two Cases  Gail Schuman

P5.310

fMRI Neuropsychological Battery for Athletes with Concussion  David Hubbard, Adam Hampshire, Adrian Owen

P5.311

The Utility of Pain Drawings in the Diagnosis and Treatment of Military Post-traumatic Headache  Alan Finkel, Juanita Yerry, Brian Ivins, Young Choi

P5.312

Clinical Course of Recovery from Concussion in Children 6-12 Years of Age  Sarah Risen, Jennifer Reesman, Gayane Yenokyan, Kelly Clark, Beth Slomine, Stacy Suskauer

P5.313

Use of a Non-invasive Neurotechnology, HIRREM, Is Associated with Improved Sleep, Mood, and Baroreflex Sensitivity in Athletes with Persisting PostConcussion Symptoms  Charles Tegeler, Catherine Tegeler, Jared Cook, Sung Lee, Meghan Franco, Lee Gerdes, Hossam Shaltout

Field Utilization of the Cleveland Clinic Concussion iPad Assessment Tool  Jay Alberts, Joshua Hirsch, Susan Linder, David Schindler Quantification of the Balance Error Scoring System with an iPad Application  David Schindler, Susan Linder, Mandy Koop, Joshua Hirsch, Daniel Kana, Jay Alberts Consequences of Traumatic Brain Injury in Male Ice Hockey Players  Ozan Toy, Mill Etienne, Ronald Bogdasarian

P5.320

Comparison of Common Football Helmets in Preventing Concussion, Hemorrhage and Skull Fracture Using a Modified Drop Test.  John Lloyd, Francis Conidi

Neuro Trauma, Critical Care, and Sports Neurology: Traumatic Brain Injury P5.321

A Multiscale Biology Approach in the Identification of Dementia Risks in Subjects with TBI History Giulio Pasinetti, Ke Hao, Drew Helmer

P5.322

MEG Findings Correlate to Speech-Language Pathology Deficits in Combat-Related mTBI and PTSD Maria DeGraba, Warren Merrifield, Erin Mattingly, Judy Mikola, Mihai Popescu, Anda Popescu, Alexander Balbir, Thomas Balkin, Joseph Bleiberg, Thomas DeGraba

P5.323

Etiology and Epidemiology of Traumatic Brain injury in Relation to Gender Differences Among African American Patients  Lien Diep, Robert Farney, Stacy Cary-Thompson, Jean Belcourt, Robert Farney, Janaki Kalyanam, Annapurni JayamTrouth

P5.324

P5.314

Onabotulinum Toxin A for the Treatment of Chronic Post-Traumatic Headache in Service Members with a History of Mild Traumatic Brain Injury  Juanita Yerry, Alan Finkel, Devon Kuehn, Steven Lewis

P5.315

P5.325

Alterations in Network Dynamics Following Blast-induced Mild Traumatic Brain Injury  Andrei Vakhtin, Paul Taylor, Corey Ford Thalamic Volumes and Exposure to Head Trauma in Retired Professional Fighters  Charles Bernick, Sarah Banks, Nancy Obuchowski, Wanyong Shin, Mark Lowe, Michael Phillips, Michael Modic, Stephen Jones

P5.316

Post-traumatic Headache in Soldiers: A Retrospective Record Review of Active Duty Soldiers Presenting to a Military Concussion Care Clinic Center for Evaluation and Treatment of Headache  Alan Finkel, Juanita Yerry, Brian Ivins, Young Choi

Is There Chronic Brain Damage in Retired NFL Players? Neuroradiology, Neuropsychology and Neurology of 45 Retired Players  Ira Casson, David Viano, E. Mark Haacke, Zhifeng Kou, Danielle LeStrange

P5.326

Progressive Return to Activity Following Acute mTBI: A Standardized Approach  Robert Labutta, Therese West, Helen Coronel, Katherine Helmick

P5.327

Interdisciplinary Assessment and Care in Service Members with Combat Related TBI and PTSD  Thomas DeGraba, James Kelly, Joseph Bleiberg, Geoffrey Grammer, Jesus Caban, Jennifer Bell, Robert Koffman

P5.328

Thromboelastography Defines Late Hypercoagulability After TBI Allie Massaro, Sean Doerfler, Kelsey Nawalinski, Nicolette Driscoll, Connie Ju, Hiren Patel, Sarah Nyirjesy, Francis Quattrone, Suzanne Frangos, Eileen Maloney-Wilensky, Robert Siman, Sean Grady, Sherman Stein, Scott Kasner, Monisha Kumar

P5.329

Mid-life Hypometabolism in the Precuneus May Be Associated with Prior History of Traumatic Brain Injury (TBI)  Salil Soman, Jauhtai Cheng, Steven Chao, Jennifer Kong, Maheen Adamson, J. Wesson Ashford, Ansgar Furst

P5.330

Antiplatelet Agent Use Impacts Mortality But Not Progression of Hemorrhagic Injury After Traumatic Brain Injury  Richard Choi, Rajanandini Muralidharan, Connie Ju, Kelsey Nawalinski, Francis Quattrone, Suzanne Frangos, Eileen Maloney-Wilensky, Sue Auerbach, Elsa Lin, Michael Miszczanczuk, Bruce Sachais, Patrick Kim, Scott Kasner, Soojin Park, Joshua Levine, W Kofke, Peter Leroux, Monisha Kumar

P5.331

The Natural History of Acute Recovery of Blast-induced Mild Traumatic Brain Injury: A Case Series During War  Jason Hawley, David Larres, Elizandro Gonzales, Walter Carr

P5.332

A Portable Non-invasive Biosensor Based Approach to Actively Assess Cognitive Function and Mild Traumatic Brain Injury  Stephen Martino, Adam Simon, David Devilbiss

P5.336

Subarachnoid Hemorrhage— Which Grading Scale Best Predicts Outcome?  Kushak Suchdev, Hardik Doshi, Mohammad Ibrahim, Navid SerajiBozorgzad

P5.337

How Much Does a Traumatic Brain Injury Cost?  Aakash Bodhit, Pratik Patel, Yasamin Daneshvar, Keith Peters, Latha Ganti

P5.338

Utility of Non-conventional MRI in Assessing White Matter Damage After Carbon Monoxide Poisoning Hiroshi Kuroda, Kazuo Fujihara, Shigeki Kushimoto, Masashi Aoki

P5.339

The Burden of Pediatric Spinal Cord Injury in the United States Shalini Selvarajah, Eric Schneider, Adil Haider, Daniel Becker, Edward Hammond

P5.340

Utility of EEG During the Early Hospital Course After Resuscitation from Cardiac Arrest  Elizabeth Cahill, David Tirschwell, Glenn Schubert, Mark Holmes, Shahin Hakimian, W. T. Longstreth, Michele Olsufka, Kim Francis

P5.341

Study of Pseudobulbar Affect Symptoms in Veterans with Mild Traumatic Brain Injury  Jennifer Fonda, Regina McGlinchey, William Milberg, James Rudolph, Phillip Hunt, Matthew Reynolds, Charles Yonan

P5.342

Management of Intracranial Hemorrhage and Return to Play in Sports: Cases Without Neurologic Deficit Jose Posas, Vernon Williams

P5.343

CNS Injuries Associated with the Sport of Ice Hockey.  Ozan Toy, Arielle Berkowitz, Mill Etienne

Neuro Trauma, Critical Care, and Sports Neurology: Outcomes P5.333

The Value of Neurocognitive Testing after Mild TBI in the Emergency Department  Latha Ganti, Pratik Patel, Aakash Bodhit, Yasamin Daneshvar, Keith Peters

P5.334

Ventilator Associated Pneumonia in Neurology and Neurosurgery Intensive Care Unit: Incidence, Risk Factors and Pathogens  Man Mohan Mehndiratta, Rajeev Nayak, Sanjay Pandey, Ajay Sharma, Archana Thakur

P5.335

Developing an Emergency Department Based Protocol for Evaluating Concussion—a Prospective Observational Study  Latha Ganti, Pratik Patel, Aakash Bodhit, Yasamin Daneshvar, Keith Peters

Available March 2014! Browse abstracts for the Annual Meeting Scientific Program with the Annual Meeting mobile app available for iPhone®, iPad®, and Android® devices. Abstracts will also be searchable online. Learn more at AAN.com/view/AM14.

Fast, Easy Registration Online  ·  AAN.com/view/AM14

101

Wednesday April 30



First Authors stand by Posters from 5:00 p.m.–6:30 p.m.



Wednesday, April 30

4:00 p.m.–5:45 p.m.

Utilizing a similar format to the popular Emerging Science Session, these dynamic sessions will feature five-minute author presentations followed by five-minutes of questions and answers. The session will conclude with all authors participating in a panel discussion. S34 MS and CNS Inflammatory Disease: Risk Factors for MS Disease and Course

S35 Cerebrovascular Disease and Interventional Neurology: Issues in Acute Treatment

4:00 p.m. S34.001 Integrating Genetic Burden and Environmental Factors to Stratify Risk for Multiple Sclerosis   Zongqi Xia, Alina von Korff, Daniel Reich, Lori Chibnik, Philip De Jager

4:00 p.m. S35.001 Minor Stroke and Rapidly Improving Stroke Symptoms: To Treat or Not to Treat?!   Clotilde Balucani, Riccardo Bianchi, Edward Feldmann, Jeremy Weedon, Steven Levine

4:10 p.m. S34.002 A Multivariate Risk Calculator for Multiple Sclerosis and Study of an Endophenotype in Siblings of People with Multiple Sclerosis   Ruth Dobson, Joanne Topping, Declan Chard, Klaus Schmierer, Paul Smith, Sreeram Ramagopalan, Gavin Giovannoni

4:10 p.m. S35.002 Expedited Code Stroke Protocol: An Updated Experience   Ilana Spokoyny, Rema Raman, Karin Ernstrom, Dawn Meyer, Justin Sattin, Thomas Hemmen, Brett Meyer

4:20 p.m. S34.003 Hormonal Contraceptives and Multiple Sclerosis Susceptibility   Kerstin Hellwig, Lie Chen, Annette Langer-Gould 4:30 p.m. S34.004 Population Attributable Fractions and Joint Effects Among Key Risk Factors for Multiple Sclerosis: The Ausimmune Study   Ingrid van der Mei, Robyn Lucas, Bruce Taylor, Anne-Louise Ponsonby 4:40 p.m. S34.005 Vaccines and the Risk of Multiple Sclerosis and Other CNS Demyelinating Diseases   Annette Langer-Gould, Lie Chen, Sara Tartof, Chun Chao, Hung-Fu Tseng 4:50 p.m. S34.006 Early Relapse-recovery Impacts Progressive Disease Course in Multiple Sclerosis   Martina Novotna, Melih Tutuncu, M. Paz Soldan, Daniel Crusan, Elizabeth Atkinson, Orhun Kantarci 5:00 p.m. S34.007 Measuring Enduring Worsening of Multiple Sclerosis in the Combirx Study   Fred Lublin, Stacey Cofield, Flavia Nelson, Ponnada Narayana, Tarah Gustafson, Jerry Wolinsky, Gary Cutter 5:10 p.m. S34.008 Are Recent Hispanic Immigrants at Higher Risk of Disability with Multiple Sclerosis?   Lilyana Amezcua, Karina Ladezma, Maziar Eslami, Jose Aparicio, Annette Langer-Gould 5:20 p.m. S34.009 CSF1R Gene Screening in a Cohort of 218 Primary Progressive Multiple Sclerosis (PPMS) Patients from the Norwegian and Swedish National PPMS Registries   Christina Sundal, Matthew Baker, Virginija Karrenbauer, Kjell-Morten Myhr, Kristoffer Haugarvoll, Shinsuke Fujioka, Hanne Harbo, Jan Aasly, Jan Hillert, Zbigniew Wszolek, Rosa Rademakers, Oluf Andersen 5:30 p.m.

Panel Discussion

4:20 p.m. S35.003 Effect of IV rtPA in Mild Strokes in the Third International Stroke Trial (IST3)   Pooja Khatri, Darren Tayama, Geoff Cohen, Richard Lindley, Joanna Wardlaw, Sharon Yeatts, Joseph Broderick, Peter Sandercock 4:30 p.m. S35.004 Futile Revascularization After Mechanical Thrombectomy for Acute Ischemic Stroke: Pooled Analysis of the Multi MERCI, TREVO and TREVO 2 Trials   Zhong-Song Shi, David Liebeskind, Bin Xiang, Sijian Grace Ge, Lei Feng, Gregory Albers, Ronald Budzik, Thomas Devlin, Rishi Gupta, Olav Jansen, Tudor Jovin, Monika Killer-Oberpfalzer, Helmi Lutsep, Juan Macho, Raul Nogueira, Marilyn Rymer, Wade Smith, Nils Wahlgren, Gary Duckwiler 4:40 p.m. S35.005 Testing the Presumption of Consent to Emergency Thrombolysis for Stroke   Winston Chiong, Anthony Kim, Ivy Huang, Nita Farahany, S. Josephson 4:50 p.m. S35.006 Prehospital Factors Associated with Stroke Misdiagnosis by EMS Providers   Ethan Brandler, Mohit Sharma, Elizabeth Helzner, Steven Levine 5:00 p.m. S35.007 CT Perfusion Variables Within 4.5 Hours of Stroke: Relating Physiology to Time Since Onset   Smriti Agarwal, Tomasz Matys, S Tulasi Marrapu, Jennifer Mitchell, P Simon Jones, Jean-Claude Baron, Elizabeth Warburton 5:10 p.m. S35.008 Acute Stroke Reperfusion Trends in the Expanded Time Window Era   Ganesh Asaithambi, Xin Tong, Mary George, Albert Tsai, James Peacock, Russell Luepker, Kamakshi Lakshminarayan 5:20 p.m. S35.009 National Trends in Utilization and Outcomes of Intravenous Thrombolytic Treatment Among Pediatric Patients with Acute Ischemic Stroke in United States   Mohammad Afzal, Saqib Chaudry, Taqi Zafar, Mohammad Owais, Malik Adil, Vishal Jani, Gautam Sachdeva, Swaroop Pawar, Syed Hussain, Adnan Qureshi 5:30 p.m.

102

S36 Neuromuscular Disease: Clinical 4:00 p.m. S36.001 ALS-Plus Syndrome: Nonmotor Features in a Large ALS Cohort   Shannon Vandriel, Leo McCluskey, Lauren Elman, Ashley Boller, Murray Grossman 4:10 p.m. S36.002 Prevalence, Course and Associations of Depression in ALS: Lack of Worsening With Disease Progression.   Nimish Thakore, Erik Pioro 4:20 p.m. S36.003 Secondary Health Conditions Among Males with Duchenne or Becker Muscular Dystrophy (DBMD)   Rebecca Napoliello, Natalie Street, Kristin Caspers, Emma Ciafaloni, Christopher Cunniff, Jennifer Donnelly, Deborah Fox, Kathy James, Joyce Oleszek, Christina Westfield 4:30 p.m. S36.004 Thymectomy for Non-thymomatous Myasthenia Gravis: A Propensity Score Matched Study.   Carolina Barnett Tapia, Hans Katzberg, Shaf Keshavjee, Vera Bril 4:40 p.m. S36.005 A Distinctive, Delayed Form of Exertional Rhabdomyolysis   Lydia Sharp, Ronald Haller 4:50 p.m. S36.006 Neuropathy Associated with Nondiabetic Obesity   J. Singleton, Eric Volckmann, Timothy Graham, Albert Smith 5:00 p.m. S36.007 Comparison of Baroreflex Sensitivity to Fall and Rise in Blood Pressure Induced by the Valsalva maneuver   Naoki Wada, Wolfgang Singer, Tonette Gehrking, David Sletten, James Schmelzer, Phillip Low 5:10 p.m. S36.008 Peripheral Nerve Amyloidosis: Phenotype, Natural History, and Autonomic Dysfunction in Inherited Versus Acquired Subtypes   Adam Loavenbruck, Wolfgang Singer, Paola Sandroni, Michelle Mauermann, P. James B. Dyck, Christopher Klein, Phillip Low 5:20 p.m. S36.009 Is the Rituximab Response in Acetylcholine Receptor Autoantibody Myasthenia Gravis Durable?   Kimberly Robeson, Benison Keung, Daniel DiCapua, Jonathan Goldstein, Kevin O’Connor, Richard Nowak 5:30 p.m.

Panel Discussion

Panel Discussion

2O14 Scientific Abstract Listing and Annual Meeting Information

S37 Clinical Aspects of Parkinson's Disease 4:00 p.m. S37.001 Low Diagnostic Accuracy of a Clinical Diagnosis of Early Parkinson’s Disease: Findings of the Arizona Parkinson’s Disease Consortium   Charles Adler, Thomas Beach, Joseph Hentz, Holly Shill, John Caviness, Erika DriverDunckley, Marwan Sabbagh, Lucia Sue, Sandra Jacobson, Christine Belden, Brittany Dugger 4:10 p.m. S37.002 Mechanisms of Profound Myocardial Norepinephrine Depletion in Parkinson Disease   David Goldstein, Patti Sullivan, Courtney Holmes, Gary Miller, Yehonatan Sharabi, Irwin Kopin 4:20 p.m. S37.003 Determining Optimal Cutoff Scores and Neuropsychological Tests for the Diagnosis of Mild Cognitive Impairment in Parkinson’s Disease   Samantha Holden, Bichun Ouyang, Glenn Stebbins, Bryan Bernard, Christopher Goetz, Jennifer Goldman 4:30 p.m. S37.004 Heart Rate Variability in LRRK2 Parkinson’s Disease   Samuel Goldman, Birgitt Schuele, Grace Bhudhikanok, Stephanie Cash, Monica Korell, Yamah Amiri, Chen Meng, Kathleen Comyns, Dolores Guest, Linda Rees, Sam Kim, Farah Kausar, Sakunthala Sundarrajan, Emily Drabant Conley, Nicholas Eriksson, Grace Liang, Melanie Brandabur, James Tetrud, J Langston, Caroline Tanner 4:40 p.m. S37.005 What Are the Determinants of Leaving the Workforce in Parkinson’s Disease?   Melissa Armstrong, Ann Gruber-Baldini, Stephen Reich, Christian Lachner, Karen Anderson, Paul Fishman, Lisa Shulman 4:50 p.m. S37.006 α-Synuclein in Red Blood Cells Is a Potential Diagnostic Biomarker for Parkinson’s Disease   Rodolfo Savica, Roy Dyer, Michelle Mielke, Bryan Klassen, Bradley Boeve, George Klee, J. Ahlskog, Walter Rocca, Marina RamirezAlvarado 5:00 p.m. S37.007 Alpha-Synuclein within Cutaneous Autonomic Nerves in Parkinson Disease: A Biomarker of Disease Severity and Autonomic Dysfunction   Christopher Gibbons, Ningshan Wang, Roy Freeman 5:10 p.m. S37.008 Elevated Blood Harmane (1-methyl-9H-pyrido[3,4-b]indole) Concentrations in Parkinson’s Disease   Elan Louis, Monika Michalec, Wendy Jiang, Pam FactorLitvak, Wei Zheng 5:20 p.m. S37.009 Oral Inosine Persistently Elevates Plasma Antioxidant Capacity in Early Parkinson’s Disease   Shamik Bhattacharyya, Rachit Bakshi, Robert Logan, Alberto Ascherio, Eric Macklin, Michael Schwarzschild 5:30 p.m.

Panel Discussion

S38 Aging, Dementia, and Cognitive and Behavioral Neurology: Plasma and Other Biomarkers 4:00 p.m. S38.001 A Plasma-based Biomarker Panel Identifies Preclinical Alzheimer’s Disease   Mark Mapstone, Massimo Fiandaca, Amrita Cheema, Xiaogang Zhong, Ming Tan, Claudia Kawas, Howard Federoff 4:10 p.m. S38.002 High Accuracy of a MicroarrayBased Blood Test for Alzheimer’s Disease   Lucas Restrepo, Phillip Stafford, Stephen Johnston 4:20 p.m. S38.003 Presence of Phosphorylated Tau, Alpha-Synuclein and Amyloid Protein in the Skin of Patients with Clinical Diagnosis of Alzheimer Disease   Ildefonso Rodriguez-Leyva, Ana Calderon-Garciduenas, Martha Santoyo, Erika Chi, Verónica MedinaMier, Maria Jimenez-Capdeville 4:30 p.m. S38.004 Increased Plasma Pyroglutamate-3 Amyloid Beta Protein Levels in Older Persons with Down Syndrome (DS)   Pankaj Mehta, Bruce Patrick, Marc Barshatzky, David Miller 4:40 p.m. S38.005 Association of Plasma Aβ Levels with MRI Markers of Cerebral Small Vessel Disease   Sara Kaffashian, Christophe Tzourio, Aicha Soumare, Carole Dufouil, Fabrice Crivello, Yicheng Zhu, Susanna SchraenMaschke, Bernard Mazoyer, Luc Buee, Stephanie Debette 4:50 p.m. S38.006 An Abeta Oligomer Receptor Antagonist and Antibodies to Specific Target Receptor Epitopes Displace Abeta Oligomers in Alzheimer’s Patient Brain Tissue Sections   Susan Catalano, Nicholas Izzo, Courtney Rehak, Raymond Yurko, Kelsie Mozzoni, Colleen Silky, Gary Look, Gilbert Rishton, Hank Safferstein, Tara Spires-Jones 5:00 p.m. S38.007 Prevalence of Lewy-type Synucleinopathy in the Submandibular Gland of Subjects with NeuropathologicallyConfirmed Dementia with Lewy Bodies.   Thomas Beach, Charles Adler, Holly Shill, Lucia Sue, Geidy Serrano, Brittany Dugger, Sandra Jacobson, Marwan Sabbagh 5:10 p.m. S38.008 Association of the MAPT with Cerebrospinal Fluid Phosphorylated Tau Levels in Frontotemporal Degeneration   Nam Eun Min, Corey McMillan, David Irwin, Virginia Lee, John Trojanowski, Vivianna Van Deerlin, Murray Grossman 5:20 p.m. S38.009 Complement Factor H Is a Biomarker for Mild Cognitive Impairment Not Due to Alzheimer’s Disease   Trung Nguyen, Kelly Watts, James Lah, Jonathan Glass, Allan Levey, William Hu 5:30 p.m.

Panel Discussion

Platform Blitzes

4:00 p.m. S39.001 Pediatric Primary Pseudotumor Cerebri Syndrome (PTCS): New Insights from Detailed Endocrine Assessments   Grace Lin, Claire Sheldon, Evanette Burrows, Marianne Chilutti, Shana McCormack, Grant Liu 4:10 p.m. S39.002 White Matter Microstructure Abnormalities in Patients with Dominant Optic Atrophy and OPA1 Mutations   Roberta Messina, Maria Rocca, Stefania Bianchi Marzoli, Iacopo Milesi, Maria Lucia Cascavilla, Melissa Petrolini, Andrea Falini, Giancarlo Comi, Massimo Filippi 4:20 p.m. S39.003 Baseline Optical Coherence Tomography (OCT) Measurements in the Idiopathic Intracranial Hypertension Treatment Trial: Correlations and Relationship to Clinical Features   Mark Kupersmith 4:30 p.m. S39.004 Opponent Mechanisms of Cone and Melanopsin Pupil Control   Geoffrey Aguirre, Manuel Spitschan, Jain Sandeep, David Brainard 4:40 p.m. S39.005 Pre-Existing Afferent Visual System Abnormalities Confound Vigabatrin (VGB) Vision Analyses of Patients with Epilepsy   Robert Sergott, Rod Foroozan, Chris Johnson, Deborah Lee, Jouko Isojarvi 4:50 p.m. S39.006 MRI Findings of Elevated Intracranial Pressure in Pseudotumor Cerebri Syndrome With and Without Papilledema   Robert Mallery, John Woo, Madhura Tamhankar, Kenneth Shindler, Yin Chen, Eric Medina, Kathleen Digre, Deborah Friedman, Grant Liu 5:00 p.m. S39.007 Four-Year Results from the Sabril® Registry Yield a Low Rate of Discontinuation Secondary to Reports of Visual Deficits   Robert Sergott, Rod Foroozan, John Pellock, R Faught, W Shields, Greg Burkhart, Vijay Prabhakaran, Sarah Torri, Deborah Lee, Jouko Isojarvi 5:10 p.m. S39.008 Visual Pathway Structure and Function, Optic Neuritis and Fatigue in Multiple Sclerosis.   Salim Chahin, Deborah Miller, Nikitha Ashok, Reiko Sakai, James Wilson, Clyde Markowitz, Dina Jacobs, Ari Green, Peter Calabresi, Elliot Frohman, Steven Galetta, Laura Balcer 5:20 p.m. S39.009 Effects of Stimulating MelanopsinContaining Retinal Ganglion Cells in Migraine Patients Using Multifocal Objective Pupillometry   Christian Lueck, Eman Ali, Teddy Maddess, Corinne Carle 5:30 p.m.

Panel Discussion

S40 General Neurology II 4:00 p.m. S40.001 DPPX Autoantibody: Frequency, Clinical Accompaniments and Outcomes   W. Oliver Tobin, Vanda Lennon, Lars Komorowski, Christian Probst, Stacey Clardy, Allen Aksamit, Claudia Lucchinetti, Sean Pittock, Maja Tippmann-Peikert, Elaine Wirrell, Andrew McKeon 4:10 p.m. S40.002 Plasma Lipids and Cerebral Small Vessel Disease   Sabrina Schilling, Christophe Tzourio, Carole Dufouil, Yicheng Zhu, Claudine Berr, Annick Alpérovitch, Fabrice Crivello, Bernard Mazoyer, Stéphanie Debette 4:20 p.m. S40.003 Neurocognitive Changes in High-Altitude U-2 Pilots: Relationship to White Matter Hyperintensities   Adam Willis, John Sladky, David Tate, Kent McDonald, Joe Wood, Paul Sherman, Peter Kochunov, Stephen McGuire 4:30 p.m. S40.004 Detection of Increased Transcripts of Human Endogenous Retrovirus in Plasma of Patients with Frontotemporal Dementia Associated Amyotrophic Lateral Sclerosis   Tariq Alfahad, Allan Levey, Avindra Nath 4:40 p.m. S40.005 Quantification of Sciatic Nerve Pathology in Inherited Neuropathies via Magnetization Transfer MRI   Richard Dortch, Lindsey Dethrage, Audra Hamilton, John Gore, Seth Smith, Jun Li 4:50 p.m. S40.006 A Single Mode of Brain Alteration in Blindness. A Multimodal MR Imaging Study.   Ritobrato Datta, Noah Benson, Aleksandra Daina, Efstathios Gennatas, Sashank Prasad, Omar Butt, Geoffrey Aguirre 5:00 p.m. S40.007 Subcortical White Matter Hyperintensities on MRI in Two Populations Exposed to Hypobaric Non-Hypoxic Conditions   Andrew Robinson, Patrick Grogan, Peter Kochunov, Paul Sherman, Stephen McGuire 5:10 p.m. S40.008 Ascending Paralysis from Rabies 17 Months Following Kidney Transplant   Sean Rogers, Mary Denny, Rebecca O’Dwyer Vourganti, Ramsey A. Falconer, Ping Zhai, Friedhelm Sandbrink 5:20 p.m. S40.009 The Effects of Combination Therapy with Sodium Valproate, Peg-alpha Interferon and Prednisolone on Clinical Manifestations of Patients With HTLV-1 Associated Spastic Paraparesis (HAM/TSP)   Ali Shoeybi, Reza Boostani, Mohammad Mehdi Etemadi, Seyed Abdolrahim Rezaee, Mehdi Moshfegh 5:30 p.m.

Panel Discussion

S41 Headache: Clinical 4:00 p.m. S41.001 Combined Concordant Peripheral Neurostimulation for Chronic Migraine Headaches: A Retrospective Analysis of 188 Consecutive Patients   Kenneth Reed, Francis Conidi, Robert Bulger, Kelly Will 4:10 p.m. S41.002 Sociodemographic, Disability, and Employment Differences Between Persons with Chronic and Episodic Migraine: Results of the CaMEO (Chronic Migraine Epidemiology and Outcomes) Study   Richard Lipton, Daniel Serrano, Dawn Buse, Kristina Fanning, Aubrey Manack, Michael Reed 4:20 p.m. S41.003 Symptom Codes and Opioids: Disconcerting Headache Practice Patterns in Academic Primary Care.   K.C. Brennan, Colin Farrell, Gregory Keough, Susan Baggaley, Karly Pippitt, Susan Pohl, Kathleen Digre, Lisa Gren 4:30 p.m. S41.004 Long-term Efficacy of Outpatient Interdisciplinary Treatment for Patients Suffering from Chronic Headaches   Mark Stillman, Steven Krause 4:40 p.m. S41.005 Influence of Psychiatric Comorbidities in Migraineurs in the Emergency Department: A Cross Sectional Analysis   Mia Minen, Kaloyan Tanev 4:50 p.m. S41.006 Headache Characteristics at Baseline in the Idiopathic Intracranial Hypertension Treatment Trial   Deborah Friedman 5:00 p.m. S41.007 Association Between Stress and Headache Frequency   Sara Schramm, Susanne Moebus, Nils Lehmann, Ursula Galli, Mark Obermann, Eva Bock, Min-Suk Yoon, H. Diener, Zaza Katsarava 5:10 p.m. S41.008 A Case Report of Acute Intracerebral Vascular Ischemic Stroke After Treatment with Dihydroergotamine in a Patient with New Onset of Migraine New Daily Persistent Headache with Thunderclap Onset   Sana Ghafoor, William Young 5:20 p.m. S41.009 Adherence to Oral Migraine Preventive Medications Among Patients with Chronic Migraine: Analysis of a Large US Health Insurance Claims Database   Zsolt Hepp, David Dodick, Sepideh Varon, Patrick Gillard, Ryan Hansen, Emily Devine 5:30 p.m.

Panel Discussion

S42 Child Neurology I 4:00 p.m. S42.001 A Novel Homozygous Mutation of SLC52A3 Gene Associated with Brown-Vialetto-Van Laere Syndrome (BVVL)   Sunil Naik, Eisha Chopra, Beth Pletcher, Chirag Gordhan, Xue Ming 4:10 p.m. S42.002 Abnormalities of the Attentional Network Following Traumatic Brain Injury in Pediatric Patients: A fMRI Study   Maria Rocca, Sandra Strazzer, Paola Valsasina, Ermelinda De Meo, Erika Molteni, Monica Recla, Susanna Galbiati, Alessandra Bardoni, Giancarlo Comi, Massimo Filippi 4:20 p.m. S42.003 Hypertension Is Associated with Increased Mortality After Ischemic Stroke in Children   Alfredo Caceres, Malik Adil, Adnan Qureshi, Lori Jordan 4:30 p.m. S42.004 Neuronal Activity Promotes Oligodendrogliogenesis and Myelination in the Mammalian Brain   David Purger, Erin Gibson, Christopher Mount, Andrea Goldstein, Grant Lin, Ingrid Inema, Sarah Miller, Gregor Bieri, J. Bradley Zuchero, Ben Barres, Pamelyn Woo, Hannes Vogel, Michelle Monje 4:40 p.m. S42.005 Identification of New Genes and Pathways for Undiagnosed Infantile Spinal Muscular Atrophy Disorders.   Lisa Baumbach-Reardon, Jesse Hunter, Mary Ellen Ahearn, Judith Hall, John Carpten 4:50 p.m. S42.006 Functional Outcome After Perinatal Cerebral Sinovenous Thrombosis: A Prospective Cohort Study   Lori Billinghurst, Michael Uohara, Daniel Licht, Rebecca Ichord 5:00 p.m. S42.007 Everolimus Long-Term Efficacy and Safety for the Treatment of Subependymal Giant Cell Astrocytoma (SEGA) Associated With Tuberous Sclerosis Complex (TSC)   David Franz, Elena Belousova, Steven Sparagana, E Bebin, Michael Frost, Rachel Kuperman, Olaf Witt, Michael Kohrman, J. Robert Flamini, Joyce Wu, Paolo Curatolo, Petrus de Vries, Noah Berkowitz, Oezlem Anak, Julie Niolat, Sergiusz Jozwiak 5:10 p.m. S42.008 Cognitive and Developmental Predictors of ASD in Infants with Tuberous Sclerosis Complex.   Shafali Jeste, Joyce Wu, Damla Senturak, Mustafa Sahin, Charles Nelson 5:20 p.m. S42.009 Memantine for the Treatment of Autism Spectrum Disorder: Overview of the Phase II Clinical Development Program   Ephraim Katz, Jordan Lateiner, Allan Spera, Robert Palmer, Stephen Graham 5:30 p.m.

Panel Discussion

S43 Epilepsy and Clinical Neurophysiology (EEG): Cognition 4:00 p.m. S43.001 A Pilot Study of a Self-Management Intervention for Cognitive Impairment in Epilepsy   Tracie Caller, Karen Secore, Robert Ferguson, Robert Roth, Faith Alexandre, Jessica Harrington, Barbara Jobst 4:10 p.m. S43.002 Cognitive Effects of Extended-release Once-daily SPN-538 (Trokendi XR™) Versus b.i.d. Immediate-Release Topiramate (TPM-IR, Topamax®) in Healthy Volunteers   Janet Johnson, Scott Brittain, Stefan Schwabe 4:20 p.m. S43.003 Stereotactic Laser Ablation of Hippocampus Leads to Better Cognitive Outcome Than Open Temporal Lobe Resections for the Treatment of Epilepsy   Daniel Drane, David Loring, Voets Natalie, Price Michele, Jon Willie, Sandra Helmers, Jeffrey Ojemann, Vaishali Phatak, John Miller, Kimford Meador, Robert Gross 4:30 p.m. S43.004 Virtual Car Accident Rates of Epilepsy Patients Are Significantly Increased by Interictal Generalized Spike Waves   Heinz Krestel, Andreas von Allmen, Christian Liechti, Maja Steinlin, Johannes Mathis, Nirkko Arto 4:40 p.m. S43.005 Mismatch of Structural and Functional Reorganization in Language Network in Left Temporal Lobe Epilepsy   Shigetoshi Takaya, Naoaki Tanaka, Hesheng Liu, Douglas Greve, Claus Reinsberger, Andrew Cole, Emad Eskandar, Steven Stufflebeam 4:50 p.m. S43.006 Efficacy of Transcranial Direct Current Stimulation on Working Memory and Mood in Patients with Temporal Lobe Epilepsy   Anli Liu, Orrin Devinsky, Andrew Bryant, Ashlie Jefferson, Daniel Friedman, Mouhsin Shafi, William Barr, Daniel Press, Susan Herman, Margaret O’Connor, Steven Schachter, Alvaro Pascual-Leone 5:00 p.m. S43.007 Seizures Lower the Pathologic Threshold for the Development of Mild Cognitive Impairment and Early Dementia in Alzheimer’s Disease   Ryan Patrick, Erin Abner, Peter Nelson, Gregory Jicha 5:10 p.m. S43.008 Key Pathways for Visual Naming and Object Recognition Revealed by Diffusion Tensor Imaging Probabilistic Tractography in Epilepsy Surgery Patients   Daniel Drane, Matthew Glasser, Natalie Voets, Jeffrey Ojemann, Amit Saindane, David Loring, Michele Price, Mirjana Ivanisevic, Vaishali Phatak, Jon Willie, Kimford Meador, John Miller, Robert Gross 5:20 p.m. S43.009 Facial Emotion Processing in Left Temporal Lobe Epilepsy   Jane Allendorfer, Heidi Heyse, Lucy Mendoza, Basia Szaflarski, Nancy Cohen, Jerzy Szaflarski 5:30 p.m.



Panel Discussion

Fast, Easy Registration Online  ·  AAN.com/view/AM14

103

Wednesday April 30

S39 Neuro-ophthalmology/ Neuro-otology II



Thursday, May 1 P6  Poster Session VI First Authors stand by Posters from 7:30 a.m.–9:00 a.m.

7:30 a.m.–11:00 a.m.

Poster Discussion Session: General Neurology V Utilizing a guided tour format, topic experts will lead attendees around the ten posters in the poster discussion session and facilitate questions with poster authors during the 90-minute author stand-by time.

P6.001

Analyses of Neural Autoantibodies by a Clinical Laboratory for the Evaluation of Paraneoplastic and NonParaneoplastic Neuronal Disorders Valerie Brachet, Malgorzata Jaremko, Brian Sansoucy, Sat Dev Batish, Keith Morneau, Zhenyuan Wang, Michael Levy, Kaylan Burnham, Joseph Higgins

P6.002

Cross-cultural Comparison of Stigma Toward Mental and Neurological Disorders  Laila Gharzai, Jennifer Harney, Suzanne Higgins, Robin High, Liyan Xu, Ashley Reynolds, Douglas Inciarte, Diego Torres-Russotto

P6.003

Efficacy of Dalfampridine in Hereditary Spastic Paraplegia: a Prospective Open Study Nicolas Collongues, Matthieu Bereau, Jean Baptiste Chanson, Gregory Tio, Yon Andoni Echaniz Laguna, Christel Depienne, Mathieu Anheim, Jerome De Seze

P6.004

Multidisciplinary Management of Cerebral Edema Associated with Fulminant Hepatic Encephalopathy in a Neurosciences Intensive Care Unit  Panayiotis Varelas, Riad Ramadan, Chandan Mehta, Marlissa Hawley, Tamer Abdelhak, Mohammed Rehman

P6.005 WITHDRAWN

P6.006

Discharge Delays on an Inpatient Neurology Service  Ayush Batra, Joel Salinas, Adam Cohen

P6.007

Taking Neurology to the Underserved—a Pilot Initiative in an Urban Homebound Program  Ritesh Ramdhani, Michelle Fabian, Ania Wajnberg, Linda DeCherrie, Stephen Krieger

P6.008

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Sera Alter Regulators of Schwann Cell Differentiation  Abhijeet Joshi, Ilja Bobylev, Christian Ritter, Andre Heinen, Helmar Lehmann

P6.009

Methotrexate Induced Cerebellar Leukoencephalopathy  Christopher Goshgarian, Abdulrahman Alwaki, Anibal Lugo, Kavita Grover

P6.010

Subclinical Primary Sjögren’s Syndrome and Associated Peripheral Neuropathy: Optimizing Diagnostic Approach.  Etienne Laverse, Amal Samaraweera, Wan Fai Ng, James Miller

NEW! e  Poster Session: Child Neurology V The ePoster session will feature a selection of posters to be presented digitally, rather than in the traditional format. Authors will be able to take advantage of the format to highlight compelling visual features such as images and videos. See poster map on page 47 for location.

P6.011

Recurrent Stroke-like Events Preceding the X-linked Charcot-MarieTooth Disease Diagnosis  Tara Kimbason, Arayamparambil Anilkumar, Oleg Bronov

P6.012

Abnormal White Matter Connectivity in Children with Autism or Sensory Processing Disorder: Overlap and Divergence.  Elysa Marco, YiShin Chang, Julia Owen, Shivani Desai, Julia Harris, Susanna Hill, Anne Arnette, Pratik Mukherjee

P6.013

An Abbreviated Exposure to Chronic Hypoxia Is Sufficient to Induce CNS Hypomyelination and Impair Motor Development in Neonatal Mice Jens Watzlawik, Meghan Painter, Louisa Papke, Robert Kahoud, William Carey, Moses Rodriguez

P6.014 Infraslow

Electroencephalography Changes in Infantile Spasms  Ken Myers, Luis BelloEspinosa, Morris Scantlebury

P6.015

Anti NMDA Receptor Encephalitis (ANMDARE): Outcome in a Cohort of 13 Children  Jay Selman

General Neurology VI P6.021

Postural Orthostatic Tachycardia Syndrome (POTS) and its associated symptoms  Anindita Deb, Karen Morgenshtern, Anna Hohler

P6.022

Neurological Sequelae of Varicella Zoster Virus Infection ( VZV): Case Series of Varied Presentations Shamaehah Javed, Maheep Singh, Stephen Marks, Ramandeep Sahni, Brij Ahluwalia-Singh

P6.023

Hashimoto’s Encephalopathy Complicated by Cerebellar Ataxia: A Case Report  Michael Hossack, Perry Richardson

P6.024

Unusual Presentation of Acute Carbon Monoxide Poisoning Shivnaveen Bains, Derrece Reid, Xuemei Huang

104

P6.025

Dabigatran—the Future of Cortical Venous Thrombosis Therapy—a Case Series Study  Thomas Mathew, Lobo Alexander, Gosala Sarma, Raghunandan Nadig

P6.026

Intrathecal Baclofen Toxicity Mimicking Nonconvulsive Status Epilepticus  Glynnis Zieman, Richard Burns

P6.027

Case Report: Uncommon Presentation of Neurosarcoidosis Ikjae Lee, Pooja Khatri, Ady Kendler, Jennifer Molano

P6.028

Central Pontine and Extrapontine Myelinolysis: Risk Factors and Clinical Expression in Liver Transplanted Patients  Silvia Favaretto, Annachiara Cagnin, Cristina Crivellin, Patrizia Boccagni, Umberto Cillo, Patrizia Burra, Marco Senzolo

P6.016

Novel Mechanism for Monitoring Cerebral Hemodynamics in Pediatric ECMO  David Busch, Ann McCarthey, Jennifer Lynch, Erin Buckley, James Connelly, Maryam Naim, Daniel Licht

P6.017

Stiff Person Syndrome in Childhood: SPS-C Recognition and Review  Bennett Lavenstein, Sarah Evans, Olga Morozova

P6.018

A Rare Case of Microcephaly-Capillary Malformation Syndrome Diagnosed via Whole Exome Sequencing  Nassim Zecavati, Reem Saadeh-Haddad, Cesar Santos, Chahira Kozma

P6.029

Unusual Case of Delayed Postpartum Preeclampsia Associated with Reversible Splenial Lesion Syndrome  Pedro Oliveira, Osama Zaidat

P6.030

Hypercholesterolemia and Neurological Diseases Related Mortality in the NEDICES Cohort  Fernando SierraHidalgo, Alvaro Sanchez-Ferro, Rocio Trincado, Jaime Díaz Guzmán, Jesús Hernández Gallego, Julian Benito-Leon, Saturio Vega, Felix Bermejo-Pareja

P6.031

Atypical Presentation of Posterior Reversible Encephalopathy Syndrome  Annapoorna Bhat, Machteld Hillen

P6.032

Neurological Disorders In Rosai-Dorfman Disease  Coralie Casulli, Nathalie Caucheteux, Agnes Fromont, Caroline Antoniol, Ayman Tourbah, Thibault Moreau

2O14 Scientific Abstract Listing and Annual Meeting Information

P6.019

Does Duration of Steroid Treatment Matter in Pdiatric Optic Neuritis?  Himali Jayakody, Daniel Bonthius, Reid Longmuir, Charuta Joshi

P6.020

Functional Neurological Disorder in the Pediatric Emergency Room: Characteristics, Outcome and Diagnostic Accuracy  Claudio De Gusmao, Rejean Guerriero, Miya Bernson-Leung, Danielle Pier, Patricia Ibeziako, Simona Bujoreanu, Kiran Maski, David Urion, Jeffrey Waugh

P6.033

Olfactory Function of the Patients with Psoriasis  Ercan Karabacak, Hakan Tekeli, Aytuğ Altundağ, Ersin Aydin, Mustafa Kendirli, Murat Salihoglu, Melih Çayonu, Halit Yasar

P6.034

The Need for Repeat Diagnostic Testing for the Identification of Ovarian Pathology in a Patient with antiNMDA Receptor Limbic Encephalitis Mona Bahouth, Carlos Pardo-Villamizar, Michael Johnston

P6.035

Quality Improvement: Maintaining an Accurate Medication List by Standardizing the Outpatient Medication Reconciliation Method  Christina Nguyen, Zhi-Jian Chen

Poster Session VI Guillain-Barre in a Small Illinois Community: An Epidemiology Perspective  Valerie Arias, Benjamin Claytor, Anand Oroskar, Mujtaba Akhter, Jorge Kattah

P6.037

The Epidemiology of Neuromyelitis Optica at a City Hospital in the Bronx, New York  Sylvia Mohen, Lenore Ocava

P6.038

Symptomatic Vitamin D Deficiency in Dubai  Stephanie Ybanez, Tania Tayah

P6.039

Hyperkalemic Periodic Paralysis Masquerading as Sleep Paralysis  Yelena Gorfinkel Pyatkevich

P6.040

POEMS Syndrome Associated with Autoimmune Limbic Encephalitis, an Unusual Occurrence  Niraj Arora, Rohini Bhole, Enrique Aradillas

P6.041

Neuroscience Education in the Medical College: The Qatar Experience  Leopold Streletz, Naim Haddad, Ziad Kronfol, Joseph Safdieh, Basim Uthman

P6.042

Posterior Reversible Encephalopathy Syndrome and GuillainBarre Syndrome in a Pregnant Lady: A Case Report from a Tertiary Teaching Hospital of South India  Dhairyawan Pokalkar, Veena Narisetty, Sateesh Kamera, Sowjanya Poosarla, Srilatha Siripuram

Movement Disorders: Spinocerebellar Ataxias P6.043

Spinal Cord Damage in Machado-Joseph Disease  Camila Fahl, Lucas Branco, Felipe Bergo, Iscia LopesCendes, Marcondes Franca, Jr.

P6.044

The Evaluation of Swallowing in Patients with Spinocerebellar Ataxia and Oropharyngeal Dysphagia: A Comparison Study of Videofluoroscopic and Sonar Doppler  Edna Marcia Abdulmassih, Helio Teive, Rosane Sampaio Santos, Bianca Simone Zeigelboim

P6.045

Polysomnographic Findings in Machado-Joseph Disease: Evaluation of 47 Patients  José Luiz Pedroso, Diogo Santos, Gilmar Prado, Lucila Prado, Luciane Carvalho, Pedro Braga-Neto, Orlando Barsottini

P6.046

De Novo Deletion of AFG3L2 Causing Spinocerebellar Ataxia Type 28 in the Context of Multiple Genomic Anomalies  Ken Myers, Jodi Chardon, Kym Boycott

P6.047

Coenzyme Q10, Statin, and Spinocerebellar Ataxias  Sheng-Han Kuo, Raymond Lo, Karla Figueroa, Stefan Pulst, Susan Perlman, George Wilmot, Christopher Gomez, Jeremy Schmahmann, Henry Paulson, Vikram Shakkottai, Sarah Ying, Theresa Zesiewicz, Khalaf Bushara, Michael Geschwind, Guangbin Xia, S Subramony, Tetsuo Ashizawa

P6.048

Audiological Evaluation in Spinocerebelar Ataxia  Hélio Teive, Bianca Zeigelboim, Walter Arruda, Ari Jurkiewicz, Denise França, Jair Marques, Hugo Carvalho, Edna Marcia Abdulmassih

P6.049

Wide Spectrum of Clinical Presentation of Spinocerebellar Ataxia Type 2  Shilpa Kolli, Anna Sorokin, Duarte Machado

P6.050

Widespread Cerebral Cortical Damage in Machado-Joseph Disease  Thiago Rezende, Anelyssa D’Abreu, Rachel Guimarães, Iscia LopesCendes, Tátila Lopes, Gabriela Castellano, Marcondes Franca, Jr.

P6.051

Dystonia in Machado-Joseph Disease: Clinical Features and Levodopa Response  Marcelo Nunes, Alberto Martinez, Iscia Lopes-Cendes, Anelyssa D’Abreu, Marcondes Franca, Jr.

P6.052

Treatment of Spinocerebellar Ataxia with Intravenous Immune Globulin (IVIG)  Theresa Zesiewicz, Tuan Vu, Kelly Sullivan, Clifton Gooch, Israt Jahan, Christopher Ward, Seok Kim

Movement Disorders: Miscellaneous Ataxias P6.053

Paroxysmal Dysarthria and Ataxia After Treatment of Brainstem Encephalitis  James Klaas, Christopher Boes, Allen Aksamit

P6.054

Sporadic Cerebellar GADAtaxia: A Retrospective Analysis Pezhman Roohani, Adam Rizvi, Sara Mayer, Khalaf Bushara

P6.055

Elevated Thyroid Antibody Associated Sporadic Cerebellar Ataxia: A Retrospective Analysis  Pezhman Roohani, Jamie Starks, Nik Haliza Nik Hassan, Khalaf Bushara

P6.056

Autoimmune Cerebellar Degeneration with Voltage Gated Calcium Channel Antibodies: A Case Report and Study of Antibody Reactivity Marilyn McKasson, Stacey Clardy, Mark Bromberg, Noel Carlson, John Greenlee

P6.057

Cerebellar Ataxia with CoQ10 deficiency Due to a Novel Mutation in ADCK3  Emanuele Barca, Olimpia Musumeci, Lorenzo Peverelli, Anna Ciranni, Salvatore DiMauro, Michio Hirano, Catarina Maria Quinzii, Antonio Toscano

P6.058

A Novel Spinocerebellar Ataxia with Hematologic Cytopenias: Linkage Analysis and Exome Sequencing Identifies a Candidate Gene Dong-Hui Chen, Piper Below, Youngmee Sul, Mark Matsushita, John Wolff, Emily Bonkowski, Wendy Raskind, Thomas Bird

P6.059

iPatax: A New Method for Quantitative Assessment for Motor Coordination of Ataxia  Masayoshi Tada, Jun Tokunaga, Takahiro Nagai, Masatoyo Nishizawa, Osamu Onodera

P6.060

Mutations in PNPLA6 Cause a Range of Neurodegenerative Phenotypes  Stephan Zuchner, Matthis Synofzik, Marie Coutelier, Charles Marques Lourenço, Tobias Haack, Rebecca Schüle, Wilson Marques Junior, Ludger Schols, Giovanni Stevanin



P6.061

Spinocerebellar Ataxias with Hypogonadism: Unraveling a Novel Group of Inherited Neurometabolic Disorders  Charles Lourenco, Claudia Sobreira, Roberto Giugliani, Stephan Zuchner, Wilson Marques, Jr.

P6.062

The Use of Adjustments to Facilitate the Written in Patients Diagnosed with Spinocerebellar Ataxia  Thais Canelossi Rosa, Renato Nickel, Paulo Liberalesso, Helio Teive

Movement Disorders: Parkinson’s Disease Imaging P6.063

Cognitive Associations of White Matter Hyperintensities in NonDemented Parkinson’s Disease Patients: A Voxel-Wise Lesion Probability Study Elijah Mak, Michael Dwyer, Deepa Ramasamy, Wing Au, Louis Tan, Robert Zivadinov, Nagaendran Kandiah

P6.064

A Longitudinal (11C)(±) Dihydrotetrabenazine PET Study of Gender Difference in the Progression of Dopaminergic Dysfunction in the Parkinsonian Caudate Nandhagopal Ramachandiran, Michael Schulzer, Lisa Kuramoto, Jacquelyn Cragg, Vesna Sossi, Raúl de la Fuente-Fernández, A Stoessl

P6.065

Hyperechogenicity of Substantia Nigra: A Potential Disease Progression Marker in Early Onset Parkinson’s Disease (EOPD) Balaji Krishnaiah, Kala Venkiteswaran, Vikram Shivkumar, Timothy Gilmour, Nitish Harid, Robert Saadi, Thyagarajan Subramanian

P6.066

Mapping Track Density Changes in Nigrostriatal and Extranigral Pathways in Parkinson’s Disease Gaëtan Garraux, Erik Ziegler, Maud Rouillard, Elodie André, Tim Coolen, Johan Stender, Evelyne Balteau, Christophe Phillips

P6.067

Subcortical Atrophy Is Associated with Cognitive Impairment in Mild Parkinson’s Disease: A Combined Volumetric and Vertex-Based Shape Analysis Study  Elijah Mak, Niels Bergsland, Robert Zivadinov, Kandiah Nagaendran

P6.068

Cerebellar Atrophy in Patients with Parkinson´s Disease Using the SUIT Tool for Voxel-Based Morphometry Camila Piccinin, Maria Cristina Santos, Luiza Piovesana, Rachel Guimaraes, Brunno Campos, Lidiane Campos, Paula Azevedo, Fabio Torres, Marcondes Franca Jr, Augusto Amato-Filho, Iscia Lopes-Cendes, Fernando Cendes, Anelyssa D’Abreu

P6.069

Quantitative MRI Biomarker Study in Parkinson’s Disease: High-field 1H-MR Spectroscopic and Multi-Modal MRI Longitudinal Study of the Substantia Nigra  Navid Seraji-Bozorgzad, Fen Bao, Natalya Shneyder, Edwin George, Carla Santiago Martinez, Veronica Gorden, Shana Krstevska, Christina Caon, Omar Khan

P6.070

Accuracy and Diagnosis Cutoff Points of 123I-metaiodobenzylguanidine Myocardial Scintigraphy for Lewy Body Disease Diagnoses in Parkinsonian Syndromes: A Study of 62 Consecutive Patients in an Expert Center. Guillaume Lamotte, Adrien Lebasnier, Denis Agostini, Gilles Defer

P6.071

Multi-Modal High-Field MRI Longitudinal Study of the Deep Gray Matter, Frontal Lobe, and Corpus Callosum in Parkinson’s Disease.  Raeesa Khan, Fen Bao, Natalya Shneyder, Navid SerajiBozorgzad, Krishna Thakore, Carla Santiago Martinez, Veronica Gorden, Edwin George, Shana Krstevska, Omar Khan

P6.072

Therapeutic Occupany of the Dopamine Receptor Agonist Pramipexol in Parkinson´s Disease (18F-Fallypride PET study)  Angela Deutschlaender, Christian La Fougere, Guoming Xiong, Kai Bötzel, Paul Cumming

Movement Disorders: Deep Brain and Other Stimulation/Imaging and Other Biomarkers P6.073

Stimulating Frontostriatal Circuitry to Treat Motor and Non-Motor Symptoms of Parkinson’s Disease Nolan Williams, Baron Short, Alexandra Jeffery, Emily Williams, Colleen Hanlon, Gregory Sahlem, Jeffery Korte, Gonzalo Revuelta, Mark George

P6.074

Tinnitus After Deep Brain Stimulation Surgery, a Case Series Umer Akbar, Geoffrey Panjeton, Patrick Antonelli, Pam Zeilman, Takashi Morishita, Michael Okun

P6.075

Clinical Manifestations of Tolerance to Deep Brain Stimulation  Deepal Shah, Joohi Jimenez Shahed

P6.076

Use of Interleaving in Deep Brain Stimulator Programming in Patients with Movement Disorders  Joohi Jimenez Shahed, Olga Waln

P6.077

Clinical Significance of Abnormal Electrode Impedance Readings in Deep Brain Stimulation for Treatment of Movement Disorders  Olga Waln, Joohi Jimenez Shahed

P6.078

A Case of Dystonic Head Tremor Treated with Bilateral Globus Pallidus Pars Interna Deep Brain Stimulation  Joanna O’Leary, M Brodsky

P6.079

Parkinson’s Disease Is Associated with Enhanced Pain-Related Disability and the Selective Loss of Gray Matter in Subcortical Regions of the Brain Related to Pain Processing  Andrew Ahn, Jared Tanner, Ann Horgas, Michael Okun, Catherine Price

P6.080

Effect of Laterality in Parkinson`s Disease: A Voxel-based Morphometry Study  Maria Cristina Arci Santos, Lidiane Campos, Rachel Guimaraes, Camila Piccinin, Paula Azevedo, Luiza Piovesana, Brunno Campos, Augusto Amato-Filho, Fernando Cendes, Anelyssa D’Abreu

Fast, Easy Registration Online  ·  AAN.com/view/AM14

105

Thursday May 1

P6.036



Thursday, May 1 P6.081 (18F)FDG PET, (18F)FP-CIT

PET and MR Morphometry in Lewy Body Dementia: Comparison with Alzheimer Disease  Hyunjin Kim, Seok Min Kim, Hyuk Jin Yun, Sujeong Kim, Doris Doudet, JongMin Lee, Chong S. Lee

P6.082

Delivery of GDNF to the Brain by Novel Nanovesicles for the Treatment of Parkinson’s Disease  Eliahu Heldman, Sarina Grinberg, Charles Linder, Mary Popov, Irwin Hollander

Neuropathy: Imaging and Biomarkers P6.083

High Resolution Ultrasound in Combat-Related Peripheral Nerve Injuries: A Case Series  Jonathan Smith, Matthew Miller, Craig Carroll, Walter Faillace, Leon Nesti, Christina Cawley, Mark Landau

P6.084

Accuracy of Ultrasound for Diagnosis of Carpal Tunnel Syndrome in Patients with Bifid Median Nerve  Jonathan Beary, Seby John, Youran Fan, Steven Shook

P6.085

Distinctive Patterns of Sonographic Nerve Enlargement in Charcot-Marie-Tooth type 1A and Hereditary Neuropathy with Pressure Palsies.  Stephan Goedee, Geert Brekelmans, Leonard Van den Berg, Leendert Visser

P6.086

Peripheral Nerve Ultrasound in Small Fiber Neuropathy  Hamid Ebadi, Hans Katzberg, Mylan Ngo, Vera Bril

P6.087

Neuromuscular Ultrasound Findings in Eosinophilic Fasciitis Sarah Stone, Lisa Hobson-Webb, Justin Mhoon, Amanda Guidon, Carolina De Jesus-Acosta, Michael Cartwright

P6.088

The Value of Including Sweat Gland Nerve Fiber Density (SGNFD) Analysis in the Neuropathy Workup  Amiram Katz, Janet Berkley

P6.089 99mTc-DPD

Cardiac Scintigraphy in Familiar Amyloidosis  Suzane Ferreira, Caroline Amaral, Osvaldo Nascimento, Claudio Tinoco, Ribeiro Sandra, Victor Kosac, Frederico Prado

P6.090

Blood Pressure Dipping During the Deep Breathing Maneuver (BPDB) While Supine May be a Marker of Severe Sympathetic Denervation Alexandru Barboi, Vivialyn Cadell

P6.091

Increased Frequency of Rhabdomyolysis in Familial Dysautonomia  Jose-Alberto Palma, Lucy Norcliffe-Kaufmann, Felicia Axelrod, Horacio Kaufmann

P6.092

Subacute Onset of Severe CIDP Weakness Associated with Tumorlike Nerve Root Involvement: A Case Report  Sharon Stoll, Goran Rakocevic

Neuromuscular Disease P6.093

Peripheral Neuropathy (PN) in Individuals with Neurofibromatosis Type 1 (NF1) and Plexiform Neurofibromas (PNF)  Tanya Lehky, Justin Kwan, Eva Dombi, Andrea Baldwin, Srivandana Akshintala, Andy Gillespie, Brigitte Widemann

P6.094

Evaluation of Central and Peripheral Neuropathy in Type 2 Diabetes: A Case-Control Study Prasanna Venkatesan Eswaradass, Ramadoss Kalidoss

P6.095

Idiopathic Peripheral Neuropathy and Subsequent Development of Diabetes Mellitus  Ritika Mahajan, Molly King

P6.096

Opioid Usage in Peripheral Neuropathy: A Population-Based Study  E. Matthew Hoffman, Nathan Staff, Christopher Klein

P6.097

Reference Attributes of Nerve Conduction and Ethnicity: Comparison in Northern Plain Indians, Mexican Americans and Caucasians  Rajat Lahoria, William Litchy, P. James B. Dyck, Jenny Davies, Rickey Carter, Peter Dyck

P6.098

A Population-Based Epidemiologic Study of Adult Neuromuscular Disease in the Republic of Ireland  Stela Lefter, Orla Hardiman, Aisling Ryan

P6.099

Trends in Outcome and Cost of Hospitalization of Elderly Myasthenia Gravis Patients Treated with Plasmapheresis from 1992 to 2009 Sedeek Elmoursi, Mohammad El-Ghanem, Ankit Pahwa, Wenzhuan He, Nizar Souayah

P6.100

Emerging Epidemiological Trends of Autoimmune Myasthenia Gravis in Connecticut  Matthew Imperioli, Agnes Acsadi

P6.101

Fainting in Teenagers Is not Always Faking  Sreenivas Avula, Manikum Moodley

P6.102

CNS Toxoplasmosis: A Serious Complication of Immunotherapy in the Neuromuscular Patient  Dan Bernardo, Nizar Chahin

P6.103

Fingolimod (FTY720) Oral for the Treatment of Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): Study Design of the Phase 3 FORCIDP Trial  Hans Hartung, Gen Sobue, Marinos Dalakas, Norman Latov, Jean-Marc Leger, Ingemar Merkies, Eduardo NobileOrazio, Katherine Agoropoulou, Dieter Häring, Lixin Zhang-Auberson, Philipp Von Rosenstiel, Richard Hughes

P6.104

Characteristics of Muscle Cramps in Patients with Polyneuropathy  Hans Katzberg, Sarah Maxwell, Seint Kokokyi, Hamid Ebadi, Ari Breiner, Vera Bril

P6.105

Electrodiagnostic Profile of Demyelination in Diabetic Neuropathy: A novel approach  Zubeda Sheikh, Ankit Pahwa, Hongxin Chen, Nizar Souayah

106

7:30 a.m.–11:00 a.m. P6.106

West Nile Virus Encephalomyelityis Simulating Brain Death  Channaiah Srikanth-Mysore, John Bertoni, Pariwat Thaisetthawatkul, Matthew White, Jose Americo Fernandes-Filho

P6.107

Zoster Associated Limb Paresis (ZALP) Is Associated with Prolonged Weakness and Pain: A Natural History Study  Alex Nelson, James Watson, Haatem Reda, Lyell Jones

P6.108

Branching Enzyme Deficiency: Expanding the Clinical Spectrum Carmen Paradas, Orhan H. Akman, Carolina Ionete, Heather Lau, Peter Riskind, David Jones, Thomas Smith, Michio Hirano, Salvatore DiMauro

P6.109

Oxidative Metabolism During Forearm Exercise in McArdle Disease  Ronald Haller, Lydia Sharp, Lauren Phillips, Marta Newby, Phil Wyrick, Katja Heinicke

P6.110

The Pattern of Pain in Carpal Tunnel Syndrome Follows a Bell-shaped Curve  Benn Smith, Mark Ross, Brent Goodman, Greg Thaera, Jonathan McKinnon

P6.111

When Expected Turns Unexpected: A Case of Subacute Progressive Weakness and Paresthesias of the Distal Lower Extremities Following a Brief Diarrheal Episode.  Divpreet Kaur, Yadira Velazquez-Rodriguez, Aiesha Ahmed

MS and CNS Inflammatory Disease: Neuroimaging P6.112

Clinical Impact of Brain Tissue Damage Quantified by Fully Automated Analysis of MR Images in Patients with Multiple Sclerosis  Alaleh Raji, Gerhard Winkler, Lothar Spies, Anja Tewes, Roland Opfer

P6.113

Sub-optimal Response to Therapy in Disease-free MS Patients: A Paradox?  Fernando Figueira, Gustavo Figueira, Paula Soares

P6.114

Longitudinal Effects of Interferon-beta-1a Treatment on Cortical Thickness in Relapsing-Remitting Multiple Sclerosis Patients  Anat Achiron, Chen Hoffmann, Yael Nissan, Shmuel Miron

P6.115

Associations Between Changes in Ferritin Levels and Susceptibility-Weighted Imaging Filtered Phase in Patients with Relapsing-Remitting Multiple Sclerosis over Six Months Therapy with Interferon Beta-1a  Michael Dwyer, Robert Zivadinov, Silva Markovic-Plese, Niels Bergsland, Mari Heininen-Brown, Ellen Carl, Cheryl Kennedy, Bianca Weinstock-Guttman, Brooke Hayward, Fernando Dangond

P6.116

Evolution of Corpus Callosum Index in Patients with Relapsing Remiting Multiple Sclerosis Treated with Natalizumab  Eva Costa Arpin, Tania Garcia Sobrino, Clara Dominguez Vivero, M. C. Amigo, Jose Prieto, Ana Rodriguez Regal, Manuela Lema Bouzas

2O14 Scientific Abstract Listing and Annual Meeting Information

P6.117

Corpus Callosum Volume Change in the First Year Is the Strongest Predictor of 9-year Clinical Disability in Multiple Sclerosis  Dana Horakova, Tomas Kalincik, Jan Krasensky, Manuela Vaneckova, Zdenek Seidl, Eva Havrdova

P6.118

A New Composite Scale of MRI-defined Disease Severity in Multiple Sclerosis  Mohit Neema, Antonia Ceccarelli, Brian Healy, Bonnie Glanz, Shahamat Tauhid, Gloria Kim, Jennifer Miller, Rohit Bakshi

P6.119

Fully Automated Detection and Quantification of T1 Hypointense Lesions in Multiple Sclerosis  Alaleh Raji, Gerhard Winkler, Lothar Spies, Anja Tewes, Roland Opfer

P6.120

Cerebellar and Brain Gray-Matter Damage Predicts Fatigue in Multiple Sclerosis  Alfredo Damasceno, Benito Damasceno, Fernando Cendes

P6.121

Abnormal White Matter Fraction Predicts Cognitive Dysfunction in Multiple Sclerosis Patients  Manuela de Stefano, Francesco Patti, Luigi Lavorgna, Patrizia Montella, Silvia Messina, Chisari Clara Grazia, Domenico Ippolito, Roberta Lanzillo, Giuseppe Salemi, Paola Valentino, Gabriella Coniglio, Maria Buccafusca, Damiano Paolicelli, D’Ambrosio Alessandro, Vincenzo Brescia Morra, Giovanni Savettieri, Bruno Alfano, Antonio Gallo, Isabella Simone, Mario Zappia, Panetta Valentina, Simona Bonavita, Gioacchino Tedeschi

P6.122

Diffusional Kurtosis MRI Correlates of Cognitive Functions in Primary-Progressive MS  Maria Petracca, Heidi Bender, Colleen Farrell, Roxana Teodorescu, Jonathan Howard, Claire Riley, Johanna Cahall, Franchesca Arias, Michelle Fabian, Fred Lublin, Matilde Inglese

P6.123

Functional Correlates of Impaired Working Memory in MS Patients: A Multicentre Study  Alvino Bisecco, Maria Rocca, Paola Valsasina, Khaled Abdel-Aziz, Frederik Barkhof, Christian Enzinger, Franz Fazekas, Antonio Gallo, Hanneke Hulst, Xavier Montalban, Nils Muhlert, Gianna Carla Riccitelli, Alex Rovira, Gioacchino Tedeschi, Giancarlo Comi, Massimo Filippi

P6.124

Cognitive Reserve in Multiple Sclerosis Modulates Hippocampal Functional Connectivity and Protects from Memory Deficits  Maria Rocca, Alessandro Meani, Paola Valsasina, Gianna Carla Riccitelli, Mariaemma Rodegher, Bruno Colombo, Andrea Falini, Giancarlo Comi, Massimo Filippi

P6.125

Iron in the Deep Gray Matter: Association with Cognitive Impairment in Multiple Sclerosis  Claire Modica, Robert Zivadinov, Michael Dwyer, Niels Bergsland, Andre Weeks, Ralph Benedict

P6.126

Brain White Matter Tract Microstructural Alterations in Multiple Sclerosis Patients with Depression and Fatigue: A Diffusion Tensor MRI Study  Gianna Riccitelli, Maria Rocca, Emanuele Pravatà, Elisabetta Pagani, Marta Radaelli, Claudio Gobbi, Filippo Martinelli Boneschi, Andrea Falini, Giancarlo Comi, Massimo Filippi

Poster Session VI

P6.127

Contribution of Global and Regional Damage of the Gray and White Matter to Fatigue in MS  Laura Parisi, Maria Rocca, Elisabetta Pagani, Bruno Colombo, Vittorio Martinelli, Andrea Falini, Giancarlo Comi, Massimo Filippi

P6.128

Network Efficiency as a Final Common Pathway for Cognitive Deficits in Multiple Sclerosis: A Single Network Graph Theory Study  Matteo Pardini, Varun Sethi, Nils Muhlert, Oezguer Yaldizli, Fulvia Palesi, Daniel Altmann, Maria Ron, Claudia Wheeler-Kingshott, David Miller, Declan Chard

P6.129

Microstructural Damage to NAWM and GM But Not to Cortical Lesions Contributes to Cognitive Impairment in Multiple Sclerosis: A Diffusion Tensor MRI Study  Maria Elisa Morelli, Maria Rocca, Elisabetta Pagani, Paolo Preziosa, Massimiliano Copetti, Mariaemma Rodegher, Federica Esposito, Andrea Falini, Giancarlo Comi, Massimo Filippi

P6.130

Patterns of Regional Gray Matter and White Matter Atrophy in “Cortical Multiple Sclerosis”  Laura Parisi, Maria Rocca, Flavia Mattioli, Ruggero Capra, Massimo Filippi

P6.131

The Rate of New GM Lesion Development Is Similar in all MS Disease Subtypes  Rasha Abdel-Fahim, Olivier Mougin, Christopher Allen, Alain Pitiot, Penny Gowland, Nikos Evangelou

P6.132

Global and Regional Brain Concentration of Intra- and Extracellular Sodium in MS: A 7 Tesla MRI Study  Lazar Fleysher, Roxana Teodorescu, Maria Petracca, Laura Jonkman, Niels Oesingmann, Joseph Herbert, Matilde Inglese

P6.133

Accrual and Evolution of Cortical Gray Matter Lesions in People with Relapse-onset Multiple Sclerosis Varun Sethi, Tarek Yousry, Nils Muhlert, Daniel Tozer, Daniel Altmann, Maria Ron, Claudia Wheeler-Kingshott, David Miller, Declan Chard

P6.134

MRI-Based Detection and Characterization of Leptomeningeal Contrast Enhancement in Multiple Sclerosis  Luisa Vuolo, Martina Absinta, Elizabeth Sweeney, Daniel Reich

P6.135

The Use of BigBrain in MS: An Ultrahigh-resolution 3D Template for Grey Matter MRI Segmentation  Shuang Liu, Christina Azevedo, Daniel Pelletier

P6.136

A Robust and Fast Algorithm for Quantifying Spinal Cord Cross-sectional Area in Myelitis  Govind Nair, Winston Liu, Raya Massoud, Daniel Reich, Steven Jacobson

P6.137

Relationship Between Spinal Cord Atrophy and Brain Cortical Lesions in Primary-Progressive MS Roxana Teodorescu, Maria Petracca, Colleen Farrell, Jonathan Howard, Claire Riley, Michelle Fabian, Fred Lublin, Matilde Inglese

P6.138

The Neurofunctional Basis of Sensorimotor Preservation in Multiple Sclerosis  Victoria Leavitt, James Sumowski

P6.139

Normal Appearing White Matter Injury in MS Is Affected by the Distance to the Nearest Cortical Lesion  Nikos Evangelou, Rasha AbdelFahim, Olivier Mougin, Justina Ruksenaite, Abigail Lazenbury, Penny Gowland, Alain Pitiot

Risk Factors for MS Disease and Course P6.140

Level of Homocysteine, Homocysteine Thiolactone and Antibodies Against N-homocysteinylated Proteins in Patients with Multiple Sclerosis Anna Jamroz-Wisniewska, Jerzy Beltowski, Konrad Rejdak, Halina Bartosik-Psujek

P6.141

Smoking Cessation and Disability Progression in Multiple Sclerosis: An Observational Cohort Study Cris Constantinescu, Ali Manouchehrinia, Radu Tanasescu, John Britton

P6.142

Serum Lipid and Antiphospholipid Antibodies Profiles in Different Phases of Multiple Sclerosis  Tatiana Koudriavtseva, Chiara Mandoj, Giovanni Cigliana, Giovanna D’Agosto, Paola Cordiali-Fei, Laura Conti

P6.143

Multiple Sclerosis and Premorbid Risk Behaviour: Association Is Not Necessarily Causation Christopher Hawkes, David Boniface

P6.144

Vitamin D and Multiple Sclerosis: Are We Still in the Dark?  Michael Douglas, Lindsay Durant, Ghaniah Hassan-Smith, James Hodson, John Curnow, Atalanti Tsentemeidou

P6.145

Vitamin D Deficiency in Multiple Sclerosis: Possible Influence of Circulating Vitamin D Binding Protein Levels.  Suhail Al-Shammri, Abayomi Akanji, Arpita Chattopadhyay, Chetana Madala, Reema Mathew

P6.146

Modulating Effects of WT1 on the Relationship Between Interferon-β and Vitamin D Levels in the Patients with Multiple Sclerosis  Rui Lin, Steve Simpson, Jr., Jac Charlesworth, Ingrid van der Mei, Leigh Blizzard, Niall Stewart

P6.147

The Role of Vitamin D in Optic Neuritis—an Update  Jodie Burton, Jessie Trufyn, Chelsia Tung, Misha Eliasziw, Fiona Costello

P6.151

Identification of Clostridium Perfringens Epsilon Toxin as a Candidate Trigger for New Lesion Formation in Multiple Sclerosis  Timothy Vartanian, Kareem Rumah, Jennifer Linden

P6.152

Effects of a Low Fat Plant Based Diet in Multiple Sclerosis (MS): Results of a 1-year Long Randomized Controlled (RC) Study  Vijayshree Yadav, Gail Marracci, Edward Kim, Rebecca Spain, Michelle Cameron, Shannon Overs, John McDougall, Jesus Lovera, Dennis Bourdette

P6.153

Expression of Multiple Sclerosis Susceptible Loci Genes May Assist in Diagnostic Decision Making  Michael Gurevich, Gadi Miron, Erez Hanael, Anat Achiron

P6.154

A Multiple SclerosisAssociated Single Nucleotide Polymorphism in the MERTK Receptor Is Correlated with Altered MERTK Expression  Trevor Kilpatrick, Michele Binder, Judith Field, Helmut Butzkueven, Melissa Gresle

P6.155

Is it Worth it to Study Families with Multiple Sclerosis (MS)? the Case of a Novel Rare Variant in a Novel Unexpected Interferon-stimulated Gene. Filippo Martinelli Boneschi, Federica Esposito, Ana-Maria Osiceanu, Melissa Sorosina, Davide Cittaro, Dejan Lazarevic, Elia Stupka, Giancarlo Comi

P6.156

CD58 and Multiple Sclerosis: Genetic Association, Gene Expression and Prognostic Value  Michael Hecker, Jana Blaschke, Paul Blaschke, Brit Fitzner, Dirk Koczan, Hans-Juergen Thiesen, Uwe Zettl

P6.157

An Analysis of Novel Antibody Repertoires in Patients with Multiple Sclerosis: Do Particular Antibody Genes Recognize Gray Matter Cellular Targets?  Ann Ligocki, William Rounds, Min Li, Paul Henson, Donna Graves, Elliot Frohman, Ann Stowe, Jacqueline Rivas, Alyssa Guzman, Sally Ward, Benjamin Greenberg, Nancy Monson

P6.158

Molecular Network of ChIPSeq-Based EBNA1-Target Cellular Genes Supports Biological Implications of EBV Persistence in Multiple Sclerosis Jun-ichi Satoh, Yoshihiro Kino

MS Symptoms and Comorbidities

P6.148

Vitamin D, B-Cell Immunoreactivity, and B-Cell Phenotypes in Cerebrospinal Fluid of Patients with Multiple Sclerosis  Brigitte Wildemann, Alexander Schwarz, Mirjam KorporalKuhnke, Sven Jarius, Juergen Haas

P6.159

P6.149

P6.160

Dietary Saturated Fatty Acids Promote Differentiation of Th1 and Th17 Cells and Aggravate Neuroinflammation  Ralf Linker, Markus Kleinewietfeld, De-Hyung Lee, Dominik Muller, Arndt Manzel

P6.150

Sodium Intake Is Associated with Increased Disease Activity in Multiple Sclerosis  Mauricio Farez, Marcela Fiol, Maria Gaitan, Francisco Quintana, Jorge Correale



Gustatory Dysfunction in Multiple Sclerosis  Richard Doty, Isabelle Tourbier, Fidias Leon-Sarmiento, Jayaram Udupa, Bilge Karacali, Gul Moonis, Evan Beals, Laura Fabius, Taehoon Kim, Bala Palecanda, Andre Souza Multiple Sclerosis Reported Fatigue: Obstructive Sleep Apnea and Abnormalities in Sleep Architecture in a Community Cohort  Mark Gudesblatt, Myassar Zarif, Barbara Bumstead, Lori Fafard, Marijean Buhse, Steven Brass, Konstantina Bardhi, Steven Xian

P6.161

Visual Field Defects in Multiple Sclerosis and Related Disorders  Dong Joo Yun, Jae-Gyu Kwak, Byoung-Joon Kim

P6.162

Multiple Sclerosis Exacerbation Presenting as Stress Cardiomyopathy  Tyler Webb, Tania Reyna, Robert Blair, Robert Foreman

P6.163

Headache in Multiple Sclerosis: Features and Implications for Disease Management  Jessica Wilcox, David Tabby, Muhammad Hassan Majeed, Branden Youngman

P6.164

Neuropathic Pain in Multiple Sclerosis: A Contact Heat Evoked Potential Stimulator (CHEPS) Evaluation Victor Kosac, Osvaldo Nascimento, Frederico Prado, Andre Matta, Eduardo Davidovich, Bruno Coutinho, João Dib

P6.165

Longitudinal Changes of Olfactory and Gustatory Function in Patients with Multiple Sclerosis Felix Schmidt, Christian Gertz, Florian Uecker, Lutz Harms

P6.166

Multiple Sclerosis Compromises Various Aspects of Female Sexual Function  Julia Koehn, Ralf Linker, Tassanai Intravooth, Carl Crodel, Martina Deutsch, De-Hyung Lee, Max Hilz

P6.167

Head-up Tilt Test, R-R Interval Variation and Sympathetic Skin Response in the Assessment of the Autonomic Nervous System of Patients With Multiple Sclerosis  Hizir Ulvi

P6.168

Metabolic Syndrome and Disability in Multiple Sclerosis: A Retrospective Study  Idanis Berrios Morales, Chutima Saipetch, Anya Turetsky, Kevin Kane, Neeta Garg, Peter Riskind

P6.169

Multiple Sclerosis and Stroke  Eleanor Sung, Lilyana Amezcua, Steven Cen, Aaron Krug, Nerses Sanossian

P6.170

Prevalence of Thyroid Disease in a Multiple Sclerosis Clinic Cohort Donald Barone, Serge Khelemsky, Decosy Hercules, Kathleen Barone

P6.171

A Study of Insulin Resistance in Multiplesclerosis Subjects and Healthy Controls  Myla Goldman, Scott Koenig, Rebecca Yeamans, Karen Johnston

P6.172

Multiple Sclerosis Patients with Allergies Demonstrate Better Physical Outcomes But Worse Psychological Symptoms.  Sahil Gupta, Katelyn Kavak, Barbara Teter, Bianca Weinstock-Guttman

P6.173

Right Under Our Noses: Olfactory Pathology in Central Nervous System Demyelinating Diseases Gabriele De Luca, Albert Joseph, Jithin George, Richard Yates, Marie Hamard, Margaret Esiri

P6.174

Deterioration or Improvement of Depression in Women Is Associated with Site and Size of Multiple Sclerosis Lesions  Klemens Winder, Tobias Engelhorn, Ingrid Wagner, Carl Crodel, Martina Deutsch, Julia Koehn, Ralf Linker, De-Hyung Lee, Max Hilz

P6.175

Functional Limitations Associated with Multiple Sclerosis: Findings from the US Medical Expenditure Panel Survey  Joseph Menzin, Matthew Sussman, Monica Fay, Terrie Livingston, Glenn Phillips, Ravi Iyer

Fast, Easy Registration Online  ·  AAN.com/view/AM14

107

Thursday May 1



First Authors stand by Posters from 7:30 a.m.–9:00 a.m.



Thursday, May 1 P6.176

Increased Incidence of Breast Cancer in Multiple Sclerosis: The Influence of Vitamin D and Estrogen in MS-Breast Cancer Concordance  Jacquelyn Laplant, Robert Knobler

P6.177

Smoking in Multiple Sclerosis Patients Is Negatively Associated with Patient Perceived Psychosocial Factors  Katelyn Kavak, Barbara Teter, Bianca Weinstock-Guttman

P6.178

Risk of Mood Changes with High Dose Corticosteroid Treatment for Demyelinating Event in Multiple Sclerosis  Sarah Morrow, Jennifer Barr, Heather Rosehart, Manera May, Sandra Ulch

P6.188

The Outcome of Preconceptual Counselling in Women with Epilepsy. Ellen Campbell, Beth Irwin, Inez Cooke, Stephen Hunt, John Craig, Jim Morrow

P6.189

The Effect of Valproate and Lamotrigine Monotherapy on Bone Health in Adult Epileptic Patients Mohammad Alhalabi, Ola Albaghdadi, Zaynab Alourfi, Lama Youssef

Epilepsy and Clinical Neurophysiology (EEG): MEG and Imaging P6.190

Epilepsy and Clinical Neurophysiology (EEG): Quality of Life and Comorbidities

Response-driven Models based on MRI and SPECT findings on Hippocampus for Lateralization of Temporal Lobe Epilepsy Mohammadreza Nazemzadeh, Jason Schwalb, Kost Elisevich, Hassan Bagher-Ebadian, Hamid Soltanian-Zadeh

P6.179

P6.191

Patient and Caregiver Quality of Life in Psychogenic NonEpileptic Seizures Compared to Epileptic Seizures  Ioannis Karakis, Georgia Montouris, Charitomeni Piperidou, Marta San Luciano, Kimford Meador, Andrew Cole

P6.180

Impact of Seizure Frequency Reduction on Health-Related Quality of Life Among Clinical Trial Subjects with Refractory Partial-Onset Seizures: A Pooled Analysis of Phase III Clinical Trials of Eslicarbazepine Acetate Kathryn Anastassopoulos, Fulton Velez, Rui Sousa, T. Christopher Bond, Xuezhe Wang, David Blum, Joyce Cramer

P6.181

Quality of Life and Sleep in Young Male Patients with Epilepsy Hakan Tekeli, Halit Yasar, Semih Alay, Mustafa Kendirli, Mehmet Senol, Turker Turker, Mehmet Saracoglu

P6.182

STOP-BANG Screening for Obstructive Sleep Apnea in Epilepsy Joon Kang, Maromi Nei

P6.183

Effects of Lacosamide on Sleep Parameters in Healthy Subjects: Results from an Open-label Study John Hudson, Stephen Yates, Paulette Williams, Jeff Guptill, William Byrnes, Neil D’Cruz

P6.184

Systematic Review of the Impact of Rapid Eye Movement Sleep on Seizure Frequency  Marcus Ng, Milena Pavlova

P6.185

Do Antidepressants Make Seizures More or Less Likely in Focal Epilepsy Patients Undergoing Elective EEG Monitoring?  Alyssa Brandt, Rachel Godfred, Mihir Parikh, Alan Haltiner, Nicole Fortier, Lisa Caylor, Jehuda Sepkuty, Michael Doherty

P6.186

Does Vitamin D Use Alter Seizure Collections During Elective Adult Inpatient Video EEG Monitoring? Alyssa Brandt, Rachel Godfred, Mihir Parikh, Nicole Fortier, Alan Haltiner, Lisa Caylor, Jehuda Sepkuty, Michael Doherty

P6.187

Prevalence of Metabolic Syndrome in Valproate-treated Adult Patients with Epilepsy  Aleksei Rakitin, Triin Eglit, Sulev Kõks, Margus Lember, Sulev Haldre

108

Subtraction Imaging and MR Co-registration to Increase Diagnostic Yield of Ictal and Interictal SPECT in Localization of Epileptogenic Foci in Patients with Intractable Seizures  Zachary Abramson, Asim Choudhri, Hubert Magill, James Wheless

P6.192

Magnetic Resonance Grading of Hippocampal Sclerosis in Temporal Lobe Epilepsy Patients Using an Equilibrium Model  Hassan Bagher-Ebadian, Mohammadreza Nazem-Zadeh, Jason Schwalb, Abdelrahman Hassane, Hamid Soltanian-Zadeh

P6.193

Cerebral Hyperperfusion and Vasodilatory Changes in Acute Seizure— Report of Three Cases  Balaji Krishnaiah, Sarita Said Said, Krishnamoorthy Thamburaj

P6.194

Quantitative Analyses of EEG with Special Electrodes in TGA Patients  Hye Ihn Kim, Jeong-Youn Kim, Chang-Hwan Im, Won-Joo Kim

P6.195

WITHDRAWN

P6.196

Is Presurgical MEG Useful in Intractable Temporal Lobe Epilepsy? Helen Barkan, Shannon Sparrow, Ann Marie Collier, Michael Funke

P6.197

Validation of Magnetoencephalography (MEG) as Presurgical Evaluaiton Tool in Pediatric Patients with Localization-Related Intractable Epilepsy.  Helen Barkan, Marie Collier, Shannon Sparrow, Michael Funke

P6.198

Comparison of Diagnostic Methods for Optimizing Epilepsy Surgery Outcome Including Magnetoencephalography  William Boles, Jane Boggs, Valerie Woodard, Cormac O’Donovan

7:30 a.m.–11:00 a.m. P6.200

F MRI Analysis in Chronic Migraine: Preliminary Report  Licia Grazzi, Frank Andrasik, Stefania Ferraro, Susanna Usai, Luisa Chiapparini, Maria Grazia Bruzzone, Gennaro Bussone

P6.201

White Matter Microstructure Abnormalities in Paediatric Migraine Patients: In-Vivo Measures of Brain Hyperexcitability?  Roberta Messina, Maria Rocca, Bruno Colombo, Elisabetta Pagani, Andrea Falini, Giancarlo Comi, Massimo Filippi

P6.202

A Case of Supratrochlear, Supraorbital, and Trigeminal Neuralgia Associated with Neurofibromas of Multiple Cranial Nerves  Kristina Lopez, David Watson, Jeffery Hogg

P6.203

Mid-life Migraine and Late-life Movement Disorder Symptoms: AGES-Reykjavik Study  Ann Scher, G. Ross, Sigurdur Sigurdsson, Melissa Garcia, Larus Gudmundsson, Sigurlaug Sveinbjornsdottir, Vilmundur Gudnason, Lenore Launer

Retrospective Analysis of the Predictors of Successful Posterior Fossa Decompression in Patients with Headaches Attributed to Chiari Malformation Naresh Mullaguri, Rahul Khanna, Gulshan Uppal, Prityi Rani, Natasha Kataria, Gauravjot Sandhu, Niranjan Singh

P6.213

A Nutrition Intervention for Migraines  Anne Bunner, Joseph Gonzalez, Francesca Valente, Ulka Agarwal, Neal Barnard

P6.214 Individualized

Pharmacogenetic Testing Improves Mood and Anxiety Treatment Outcomes in Chronic Migraine Patients Sandeep Vaishnavi, Qian Liu, Liz Griffin, Tim Ramsey, Mark Brennan

P6.215

A Live Patient Simulation Model to Effectively Manage Difficult Headache Patients  Fermina Pirmohamed

P6.216

P6.204

Does the New International Classification of Headache Disorders Affect the Prevalence of Aura in Patients with Migraine ?  Hossein Ansari

Chronic Migraine with Medication Overuse Is Associated with Low Cognitive Reserve  Marian Gomez Beldarrain, Ane Anton Ladislao, Urko Aguirre Larracoechea, Alberto Cabrera Zubizarreta, Isabel Oroz, Carlos GarciaMonco Carra

P6.205

P6.217

Barriers to Chronic Migraine Care: Results of the CaMEO (Chronic Migraine Epidemiology and Outcomes) Study  Dawn Buse, Richard Lipton, Michael Reed, Daniel Serrano, Kristina Fanning, Aubrey Manack

P6.206

Association of the Long Pentraxin PTX3 Gene Polymorphism (rs3815627) With Migraine in Iranian Population  Alireza Zandifar, Niloufar Iraji, Maryam Taheriun, Mohamadhasan Tajaddini, Faraidoon Haghdoost, Ehsan Zandifar, Samaneh Zandifar, Shaghayegh Javanmard

P6.207

Sinking Bone Flap Causing Paradoxical Orthostatic Headaches Mitra Assadi Khansare, Aimee Walsh, Mandy Binning

P6.208

Investigation of Chemokine Receptor CCR2V64Il Gene Polymorphism and Migraine in Iranian Population Alireza Zandifar, Maryam Taheriun, Samira Soleimani, Faraidoon Haghdoost, Mohamadhasan Tajaddini, Samaneh Zandifar, Ehsan Zandifar, Shaghayegh Javanmard

Headache: Outcomes P6.209

Idiopathic Intracerebral Hypertension (IIH)/pseudotumor: Removing Less CSF Is Best  Franchesca Fiorito-Torres, Melissa Rayhill, Michael Perloff

P6.210

Headache: Imaging and Epidemiology

Peri Ictal Headache in Epilepsy  Natarajan Visvanathan, Ramakrishnan Ramalingam, Radha Mahadevan

P6.199

P6.211

Circle of Willis, Cerebral Blood Flow, and White Matter Hyperintensities in Migraine  Brett Cucchiara, Ronald Wolf, Lidia Nagae, Scott Kasner, John Detre

P6.212

Validating a Definition of Alcohol Sensitivity in Women with Migraine  Qinyi Jiang, William Young, Michael Oshinsky, Seokmin Kim, Evan Klein

2O14 Scientific Abstract Listing and Annual Meeting Information

Bilateral Pain Hypersensitivity over the Trigeminal Region and Dental Deafferentations in Patients with Classical Trigeminal Neuralgia  Nathalie Guy, Béatrice Claise, Pierre Clavelou, Radhouane Dallel

Aging, Dementia, and Cognitive and Behavioral Neurology: Structural Imaging P6.218

Diffusion Tensor Imaging in PSEN1-Related Spastic Paraparesis Reveals Widespread White Matter Abnormalities  Steffan Soosman, Meredith Braskie, Jeffry Alger, David Wharton, John Ringman

P6.219

Shared Vulnerability of Two Synaptically-Connected Medial Temporal Areas to Age and Cognitive Decline: A 7T MRI Study  Geoffrey Kerchner, Jeffrey Bernstein, Michelle Fenesy, Gayle Deutsch, Manojkumar Saranathan, Michael Zeineh, Brian Rutt

P6.220

White Matter Disease in Behavioral Variant Frontotemporal Dementia Correlates with Risk-taking Behavior  John Powers, Corey McMillan, Katya Rascovsky, Lisa Burkholder, Murray Grossman

P6.221

The Symmetric and Asymmetric Variant of Microvascular White Matter Disease  Bernard Galea, Mushtaq Qureshi, Malik Adil, Muhammad Suri, Adnan Qureshi

P6.222

Voxel-based Morphometry Reveals Gray Matter Loss in Patients with Paget’s Disease of the Bone Carrying SQSTM1 Gene Mutations Innocenzo Rainero, Elisa Rubino, Federico D’Agata, Silvia Rossetti, Laura Gastaldi, Mauro Bergui, Laura Orsi, Lorenzo Pinessi, Giancarlo Isaia, Marco Di Stefano

Poster Session VI

P6.223

Regional Brain Differences in Cortical Thickness Between Patients with Amnesic Mild Cognitive Impairment and Alzheimer`s Disease Dementia Ignacio Demey, Fernando Ventrice, Galeno Rojas, Veronica Somale, Ricardo Allegri, Fabian Bevacqua, Sebastian Lescano

P6.224

Hippocampal Subfield Analysis in MCI Patients: Comparing FreeSurfer on 3T MRI with Hand Segmentation on 7T Data  Salil Soman, Ansgar Furst, Geoffrey Kerchner

Aging, Dementia, and Cognitive and Behavioral Neurology: Language P6.225

Functional Language Lateralization of Primary Progressive Aphasia Variants  Zachary Miller, Leighton Hinkley, Danielle Mizuiri, Susanne Honma, Anne Findlay, Bruce Miller, Srikatan Nagarajan, Maria Gorno Tempini

P6.226

A Cross-Culturally Valid Assessment of Object Semantics Bonnie Breining, Trisha Lala, Kyrana Tsapkini, Eleni Peristeri, María Macarena Martínez Cuitiño, Facundo Manes, Argye Hillis

P6.227

Neural Correlates of Sentence Repetition in the Logopenic Variant of Primary Progressive Aphasia Drew Goldberg, Anna Isenberg, Murray Grossman

P6.228

Predictors of Recovery of Chronic Aphasia  Aarushi Suneja, Marlis Gonzalez-Fernandez, Argye Hillis

P6.229

Syntactic Processing Skills in the Three Variants of PPA Rajani Sebastian, Cameron Davis, Yessenia Gomez, Lydia Trupe, Argye Hillis

Aging, Dementia, and Cognitive and Behavioral Neurology: Memory P6.235

Correlation between Cortical Thickness Measurements from Magnetic Resonance Imaging and Cognitive Performance on Episodic and Semantic Memory Tests  Ignacio Demey, Galeno Rojas, Veronica Somale, Fernando Ventrice

P6.236

Preservation of Spatial Function: Role in Differential Diagnosis of Behavioral Variant Frontotemporal Dementia  Anneliese Radke, Tracy Jerard, Joel Kramer, Katherine Possin, Nikolas Block, Alexander Beagle, Bruce Miller

P6.237

Validation of the Dynamic Affect Recognition Test (DART): Behavior and Anatomy in Neurodegenerative Disease  Anneliese Radke, Babu Adhimoolam, Tal Shany-Ur, Katherine Possin, David Marin, Diana Zackey, Pardis Poorzand, Bruce Miller, Katherine Rankin

P6.233

Sensitivity of Consensus Criteria in the Quantitative Classification of Primary Progressive Aphasia Meredith Wicklund, Joseph Duffy, Edythe Strand, Mary Machulda, Jennifer Whitwell, Keith Josephs

P6.234

Bilingualism and Language Networks in the Semantic Variant of Primary Progressive Aphasia. Ismael Calandri, Alejandra Amengual, Hernán Chaves, Cecilia Rollán, Mauricio Farez, Liliana Sabe, Cristina Medina, Griselda Russo, Silvia Vazquez, Ricardo Allegri

Anabolic Steroids Abuse and Ischemic Stroke: A Case Report and Literature Review  Ge Xiong, Arnaldo Velez, Anna Khanna

P6.262

P6.248

P6.263

A Case Series of Nonbacterial Thrombotic Endocarditis Associated with Gynecological Malignancies  Alice Schabas, Philip Teal, Samuel Yip, Sharanpal Mann

P6.249

Pituitary Apoplexy Presenting as Anterior Choroidal Artery Territory Infarct: A Case Report  Sasikanth Gorantla, Kasra Maasumi, Jason Felton, Nabeel Dar, Jongyeol Kim

P6.250

Lacunar Infarct Presenting Like Axillary Nerve Lesion: A case report  Oguzhan Oz, Serdar Tasdemir, Hakan Akgun, Semih Alay, Ahmet Cetiz, Zeki Odabasi, Seref Demirkaya

P6.239

White Matter Disease and Cognitive Impairment in FMR1 Premutation Carriers  Christopher Filley, Mark Brown, Karen Onderko, Megan Ray, Rachael Bennett, Jim Grigsby

P6.252

P6.240

Age Effects on the Neural Basis of Self-Generation in Verbal Paired Associate Learning  Jennifer Vannest, Thomas Maloney, Benjamin Kay, Miriam Siegel, Jane Allendorfer, Christi Banks, Jerzy Szaflarski

P6.253

P6.241

P6.254

P6.242

18F-FDG-PET Metabolic Patterns in the Semantic Variant of PPA: Functional/Clinical Correlations. SingleSubject 18F-FDG-PET Beyond MRI Daniela Perani, Leonardo Iaccarino, Lucia Guidi, Pasquale Della Rosa, Giuseppe Magnani, Stefano Cappa

P6.247

P6.251

P6.231

P6.232

P6.261

Cognitive Deficits of Large-Vessel and Small-Vessel Vascular Dementia  Ju-Young Na, Bong-Goo Yoo

Language Networks Imaging in Primary Progressive Aphasia in a Latin Population  Ismael Calandri, Alejandra Amengual, Hernán Chaves, Cecilia Rollán, Mauricio Farez, Liliana Sabe, Cristina Medina, Zanuzo Patricia, Jorge Campos, Gabriela Cohen, Jorge Calvar, Silvia Vazquez, Ricardo Allegri Impairment in Sentence Comprehension in Patients with the Behavioral Variant of Frontotemporal Degeneration (bvFTD)  Rebecca Williams, Katya Rascovsky, Murray Grossman

A Case of Akinetopsia  Wolfgang Grisold, Sabine Pollanz, Birgit Surböck, Barbara Horvath

P6.238

Accentuated Brain Responses During Semantic Object Memory Retrieval in Amnestic Mild Cognitive Impairment as Measured by Event-Related Potentials  Hsueh-Sheng Chiang, Raksha Mudar, Justin Eroh, Jeffrey Spence, Athula Pudhiyidath, Jeremy Tanner, Erin Venza, Audette Rackley, Kristin Martin-Cook, Kyle Womack, Elizabeth Bartz, Michael Kraut, John Hart

P6.230

P6.246

Relationship Between Dementia Severity Ratings and Memory Accuracy Versus Certainty Matthew Harris, Daniel Kaufer

P6.243

Changes of Face Recognition After Medial Temporal Lobe Resection  Masoud Majed, Emad Ahmadi, Seyed Mohammad Ghodsi, Sina Tafazoli, Abdol Hossein Abbassian

Cerebrovascular Disease and Interventional Neurology: Case Reports P6.244

A Case of Perioperative Stroke Caused by Tumor Embolus.  Stella Hughes, Annemarie Hunter, Jamie Campbell, Aidan Brady, Brian Herron, Graham Smyth, Ian Rennie, Stephen Hunt

P6.245

Thrombosis of the Vein of Trolard Secondary to Renal Minimal Change Disease: A Case Report and Literature Review  Marcelo Rocha, Steven Feske, Allan Ropper



Case of Neurosyphilis Presenting as MoyaMoya Syndrome  Saima Ali, Soundarya Gowda Two Cases of Malignant Cerebral Edema Related to Systemic Lupus Erythematous  Lauren Koffman, Khaled Asi, Ashlee Russo, Dhimant Dani, Edward Manno Case Report: Multiple Scattered Ischemic and Hemorrhagic Strokes after Transarterial Chemoembolization for Hepatocellular Carcinoma  Alhamza Al-Bayati, Douglas Smith, Elia Haddad The Clinical Features of Cerebral Vein and Sinus Thrombosis in Male Patients  Hongyan Ding, Qiang Dong

P6.255

Intracranial Venous Sinus Thrombosis: Report of Three Cases Hans Reyes Garay, Carla Sueldo Feijoo, Jorge Martin Gavidia Chucan

P6.256

Generalized Dilative Arteriopathy Without Myopathy: A New Phenotype of Pompe Disease Andoni Echaniz-Laguna, Marc Bataillard, Véronique Quenardelle

P6.257

Brain Herniation Due to Mitochondrial Encephalomyopathy, Lactic Acidosis, Stroke Like Events (MELAS) with 3256 Mutation Responsive to Decompressive Craniotomy  Chunmei Cui, Robert Schwendimann

P6.258

Cerebral Varicella Zoster Vasculopathy Sine Herpete: Atypical Ramsay-Hunt Syndrome presentation in an Immunocompetent Patient Karina Gonzalez Otarula, Verónica Bruno, Virginia Pujol-Lereis, Sebastian Ameriso

Amusia: Unique Presentation of Stroke  Charu Ramchandani, Fawaz Alsmaan, Heidi Schwarz, Ziad Alkhoury Recurrent Intra-luminal Aortic Thrombus and Ischemic Stroke in a Patient with Essential Thrombocythemia Daniel Vela-Duarte, Murray Flaster Right Hemispheric Acute Ischemic Stroke Secondary to Right Common Carotid Artery Free Floating Thrombus Due to Hypercoagulable State in an Otherwise Healthy 48-year-old Woman.  Karen Orjuela, Rick Gill, Luka Vlahovic, Sarkis Morales-Vidal

P6.264

Uncomon Cause Stroke: Thalamic Stroke as Initial Presentation of Dunnigan Familial Partial Lipodystrophy (FPLD)  Fatai Radji, Elena Leca Radu, Kahina Dannepond, Marie-Laure Nunes

P6.265

Is Achondroplasia Linked to Stroke?  Harpreet Kaur, Shilpi Mittal, Catherine Hosley

P6.266

“Pseudostroke”: Clinically Diagnosed Ischemia Shown to Be Multiple Sclerosis at Autopsy: A Case Report  Gulshan Uppal, Natasha Kataria, Prityi Rani, Douglas Miller

P6.267

Delayed Cortical Blindness After Cardiac Arrest  Anibal Lugo, Abdulrahman Alwaki, Christopher Goshgarian, Justin Belsky, Panayiotis Mitsias

P6.268

Case Report—Cerebral Amyloid Angiopathy with Granulomatous Angiitis  Ali Saeed, Vibhav Bansal, Howard Chang, Michael Flink, Anmar Razak, Syed Hussain

P6.269

Paradoxical Cerebral Embolism from Thrombolysis of a Clotted Arteriovenous Graft  Umang Shah, Ruchir Shah

P6.270

A Rare Association Between Ulcerative Colitis and Bilateral Thalamic Stroke  Sara Misthal, Dababneh Haitham, Asif Bashir, Mohammed Hussain, Mohammad Moussavi, Jawad Kirmani

P6.271

Monocular Diplopia After Left Posterior Cerebral Artery Territory Infarction  Konstantinos Papadopoulos, Brigitte Capron, Raphael Hourez

P6.272

Rapid High Volume CSF Loss: A New Cause of Coma  Minjee Kim, Rose Du, Sherry Chou

P6.273

Thrombectomy with the Penumbra 5 MAX ACE Achieves More Efficient Recanalization  Nazli Janjua, Jeffrey Farkas, Karthikeyan Arcot, Rajesh Kumar, Delbrune Jean, Nikolaos Papamitsakis, Yevgeny Margulis, Subasini Dash, Kenneth Levin, Salman Azhar

P6.259

Synthetic Cannabis and Acute Ischemic Stroke  Miya Bernson-Leung, Lester Leung, Sandeep Kumar

P6.260

A Novel Heterozygous c.164G>C Mutation in the Exon 2 of the NOTCH3 Gene Causing Cadasil Raphael Hourez, Konstantinos Papadopoulos, Guy Bruninx, Yves Sznajer

Fast, Easy Registration Online  ·  AAN.com/view/AM14

109

Thursday May 1



First Authors stand by Posters from 7:30 a.m.–9:00 a.m.



Thursday, May 1 Cerebrovascular Disease and Interventional Neurology: Risk Factors

P6.285

P6.274

P6.286

Visit-to-visit Systolic Blood Pressure Variability Predicts All-cause and Cardiovascular Mortality After Lacunar Infarct  Gary Lau, Yuen Kwun Wong, Richard Chang, KC Teo, Sonny Hon, Koon Chan, KL Wat, Raymond Cheung, Leonard Li, David Siu, Shu Leong Ho, Hung Fat Tse

P6.275

Medicare’s New Two Midnight Rule for In-patient Status Admission Applied to Transient Ischemic Attack Patients Predicted by Hypertension History and Age  Maria Chavez-Keatts, Dominique Monlezun, Jr, Alexander George, Ramy El Khoury, Sheryl Martin-Schild

P6.276

High Burden of Brain Microvascular Disease in Difficult-tocontrol Hypertension  Maria Zurru, Claudia Alonzo, Laura Brescacin, Ariel Luzzi, Luis Camera, Gabriel Waisman, Edgardo Cristiano

P6.277

Comparison of Classical Risk Factors, Lypids, Stress and Depression Among Patients with First Ischemic Stroke and Acute Myocardial Infarction in a Center from Buenos Aires.  Dario Lisei, Martin Lopez Vicchi, Gabriel Persi, Matías Failo, Ricardo Iglesias, Maria Ballarino, Sebastian Camerlingo, Virginia Laura Parisi, Emilia Gatto

P6.278

Analysis of Comorbidities in Ischemic Stroke Patients  Thomas Cochran, Jose Chaves, Eric Fulmer, Dawn Blackhurst, Shannon Sternberg, R. Leacock, Thomas Nathaniel

P6.279

Low Density Lipoprotein Receptor Related Protein-1 and 6 Gene Variants and Ischemic Stroke Risk Andrea Harriott, Michael Heckman, Sruti Rayaprolu, Alexandra Soto-Ortolaza, Rainer Malik for METASTROKE Consortium, John Cole, James Meschia, Owen Ross

P6.280

Stroke in Very Old Patients  Drini Dobi, Mira Kapisyzi, Jera Kruja

P6.281

Analysis of the Relation Between Chronic Kidney Disease and Acute Ischemic Stroke.  Patricio Blaya, Mariano Borrelli, Mariela Cabrera, Claudia Gonzalez, Walter Gramajo, Javier Rolle, Nestor Estevez, Jorge Gimenez, Cristina Trujillo, Marcelo Mattiazzi

P6.282

The Relationship Between Leukocytosis and Time to Neurodeterioration  Amelia Boehme, James Siegler, Karen Albright, Alexander George, Dominique Monlezun, Jr, Adam Friedant, Brittany Gouse, T. Beasley, Sheryl Martin-Schild

Neuro-ophthalmology/ Neuro-otology II P6.283

Incidence, Seasonality, and Comorbidity in Vestibular Neuritis Ivan Adamec, Magdalena Krbot, Mario Habek

P6.284

Retinal Ganglion Cell Injury Precedes RNFL loss in Acute Optic Neuritis  John Guy, Vittorio Porciatti, William Feuer, Angela Herro, Byron Lam

110

Gordon Holmes 100 Years Later: Cortical Folding Predicts Retinotopic Organization  Noah Benson, Omar Butt, David Brainard, Geoffrey Aguirre Retinal Structure and Function in Adults with Refractory Complex Partial Seizures (rCPS) Treated with Vigabatrin: Initial Results of the Sabril Vision Study  Robert Wechsler, Chris Johnson, Robert Sergott, Kenneth Laxer, Yekaterina Dribinsky, Colleen Canavan, Jouko Isojarvi, Deborah Lee

P6.287

Vision-Based Concussion Testing in a Youth Ice Hockey Cohort: Effects of Age and Visual Crowding  Jennifer Morganroth, Steven Galetta, Laura Balcer

P6.288

Saccade Properties and Fixation Instability Differentiate Ataxias  Pamela Federighi, Francesca Rosini, Elena Pretegiani, Claudia Vinciguerra, Gabriele Lucii, David Zee, R. John Leigh, Lance Optican, M.T. Dotti, Antonio Federico, Alessandra Rufa

P6.289

Quantitative Videooculography to Differentiate Stroke from Vestibular Neuritis in Acute Vertigo—Vestibulo-ocular Reflex Gain Distributions and Optimal Test Thresholds for Diagnosis  Ali Saber Tehrani, Georgios Mantokoudis, Amy Wozniak, Karin Eibenberger, Jorge Kattah, Cynthia Guede, David Zee, David Newman-Toker

P6.290

Susac’s Syndrome: Five Cases with Predominant Branch Retinal Artery Occlusion  Thomas Seifert-Held, Alexander Barounig, Maria Storch, Hans Offenbacher, Martin Weger, Beate Langner-Wegscheider, Franz Fazekas

P6.291

Correlation of Acute Phase Reactants and Temporal Artery Biopsy (TAB) in Patients with Giant Cell Arteritis (GCA)  Padmaja Sudhakar, Sachin Kedar

P6.292

Clinical and Electrophysiological Photostress Recovery Times in Distinguishing Demiyelinating Optic Neuritis And Maculopathy Fethi Idiman, Ahmet Onur Keskin, Mahmut Kaya, Egemen Idiman, Onur Bulut

P6.293

A Retrospective Study of Chronic Relapsing Inflammatory Optic Neuropathy (CRION)  Padmaja Sudhakar, Sachin Kedar, Joseph Berger

P6.294

Eye Movement Features in Rare Hereditary Parkinsonian Syndromes  Elena Pretegiani, Gabriele Lucii, Pamela Federighi, Francesca Rosini, Antonio Federico, Alessandra Rufa

P6.295

Ocular Motility Disturbances in Orbitofacial Neurofibromatosis Type 1  Thomas Bosley, Ibrahim Alorainy, Jose Morales, Imtiaz Chaudhry, Darren Oystreck

P6.296

Neurosurgical Cases with Cortical Vision Loss Followed by Improvement  Bonnie Keung, Julian Lin, Jeffrey Klopfenstein, Jorge Kattah

P6.297

Optical Coherence Tomography Quadrant Analysis of Retinal Nerve Fiber Layer in Relapsing and Remitting Multiple Sclerosis  John Rose, Anette Fjeldstad

7:30 a.m.–11:00 a.m. P6.298

Demyelinating Optic Chiasmopathy Due to Mycobacterium Haemophilum in a Patient with AIDS  Alexander Merkler, George Parlitsis, Alison May, Dara Bier, Sara Simpson, Sarju Patel, Ehud Lavi, Audrey Shuetz, Marc Dinkin

P6.299

Visual Evoked Potential and Magnetic Resonance Imagine Are More Effective Markers of Multiple Sclerosis Progression Than Laser Polarimetry with Variable Corneal Compensation Ema Kantorova, Peter Žiak, Koyšová Mária, Kamil Zeleňák, Egon Kurča, Mária Hladká, Alexandra Sedláková

P6.300

Presence of AQP4 Antibodies Correlates with Negative Outcome of Optic Neuritis  Jana Lizrova Preiningerova, Petra Nytrova, Pavel Kuthan, Pavel Diblik, Eva Havrdova

P6.301

Evidence of Multi-Domain Mild Cognitive Impairment in Idiopathic Intracranial Hypertension  Anat Kesler

P6.302

‘Ping-Pong’ Gaze in Hypoglycemic Encephalopathy  Saima Ali, Scott Haines

P6.303

Do Not Forget Susac Syndrome in Patients with Unexplained Acute Confusion  Michael Star, Maria Bruzzone, Felipe De Alba, Rick Gill, Michael Schneck, Jose Biller

P6.304

Clinical Utility of Cervical Vestibular Evoked Myogenic Potential (VEMPc) in Ménière’s disease Guillermo Videla, Ana Bisonni, Jorge Norscini, Edgardo Cristiano

P6.305

An Unusual Case Of Idiopathic Intracranial Hypertension Presenting with Simultaneous IIIrd, VIth and V11th Nerve Palsies  Akshat Katyayan, Venu Parachuri, Delphin Sallowm, Ryan Walsh

P6.306

Restricted Diffusion Imaging in Active Seizure: A Case Report Adnan Subei, Eric Eggenberger

P6.307

Presence of AQP4 Antibodies Correlates with Negative Outcome of Optic Neuritis  Jana Lizrova Preiningerova, Petra Nytrova, Pavel Kuthan, Pavel Diblik, Eva Havrdova

P6.308

Diplopia and Esophoria Induced by Medial Thalamic Deep Brain Stimulation  Barbara Kelly Changizi, Catherine Cho, Brian Kopell, Janet Rucker

Aging, Dementia, and Cognitive and Behavioral Neurology: Imaging P6.309

Decline in Perceptual Motor Speed and Cognitive Flexibility Associated with Regional Patterns of FDG PET Hypometabolism  Alan Lerner, Alok Sachdeva, Curtis Tatsuoka

P6.310

A fMRI Graph Theory Study of the Effect of Gender and Aging on Topology of Functional Brain Networks Gianna Riccitelli, Maria Rocca, Paola Valsasina, Alessandro Meani, Federica Agosta, Massimo Filippi

2O14 Scientific Abstract Listing and Annual Meeting Information

P6.311

Early Striatal Perfusion Deficits in Autosomal Dominant Alzheimer Disease Detected with Arterial Spin Labeled MRI.  Eric McDade, Albert Kim, Jeffrey James, Davneet Minhas, Snezana Ikonomovic, Oscar Lopez, Beth Snitz, Julie Price, James Becker, Chester Mathis, William Klunk

P6.312

The Effect of Age of Onset on the Brain Functional Connectivity in Alzheimer’s Disease: A Graph Analysis Study  Elisa Canu, Federica Agosta, Sebastiano Galantucci, Alessandro Meani, Giuseppe Magnani, Alessandra Marcone, Andrea Falini, Giancarlo Comi, Massimo Filippi

P6.313

Microstructural White Matter Alterations Correlate with Cerebral Amyloid Angiopathy Burden and Cognitive Measures: A DTI/PET Study  Yael Reijmer, Panagiotis Fotiadis, Sergi Martinez-Ramirez, Aaron Schultz, Anne Reed, Alison Ayres, Kristin Schwab, Jonathan Rosand, Anand Viswanathan, Keith Johnson, Steven Greenberg, Edip Gurol

P6.314

Strategic Choice in Frontotemporal Dementia: A Pilot Study  Alessandra Dodich, Chiara Cerami, Nicola Canessa, Chiara Crespi, Alessandra Marcone, Andrea Falini, Stefano Cappa

P6.315

Decreased White Matter NAA in Alzheimer’s Disease  Navid SerajiBozorgzad, Fen Bao, Krishna Thakore, Omar Khan

P6.316

Medial Parietal Cortex GABA Measurements in Alzheimer’s Disease Are Inversely Associated with Functional Response  Novraj Dhanjal, Mark McPhail, Marzena Wylezinska, Richard Wise

P6.317

Dorsolateral Prefrontal Cortex Modulation by Caudate Dopamine During a Working Memory Task in Parkinson Disease  Joseph Masdeu, Daniel Eisenberg, Catherine Hegarty, Brett Cropp, Daniel Rubinstein, Philip Kohn, Karen Berman

P6.318

Region Specific Alpha-band Resting-state Functional Connectivity Predicts Focal Cognitive Deficits in Alzheimer’s Disease Spectrum Kamalini Ranasinghe, Leighton Hinkley, Alexander Beagle, Danielle Mizuiri, Anne Dowling, Susanne Honma, Mariel Finucane, Carole Scherling, Bruce Miller, Srikatan Nagarajan, Keith Vossel

P6.319

Florbetapir F18 Positron Emission Tomography Identification of Beta-Amyloid in the Living Brain: A Consecutive Clinical Case Series Effie Mitsis, Heidi Bender, Lale Kostakoglu, Josef Machac, Jane Martin, Jennifer Woehr, Martin Goldstein, Mary Sano, Samuel Gandy

P6.320

Differences in 11C-PIBPET Imaging Patterns in Patients with Alzheimer’s Disease Without Microbleeds and Those with Cerebral Amyloid Angiopathy  Yuichi Hayashi, Jun Shinoda, Nobuaki Yoshikura, Masahiro Waza, Yoshitaka Asano, Akio Kimura, Takashi Inuzuka



Poster Session VI

First Authors stand by Posters from 7:30 a.m.–9:00 a.m. P6.321

Association Between Longitudinal Increases in Serum Glucose and Metabolic Decline in Azheimer’s Disease-Related Brain Regions Christine Burns, Alfred Kaszniak, Kewei Chen, Wendy Lee, Daniel Bandy, Richard Caselli, Eric Reiman Effects of β-Amyloid Load on White Matter Integrity in Dementia with Lewy Bodies  Zuzana Nedelska, Christopher Schwarz, Bradley Boeve, Robert Reid, Scott Przybelski, Jeffrey Gunter, Matthew Senjem, Glenn Smith, Tanis Ferman, Yonas Geda, David Knopman, Ronald Petersen, Clifford Jack, Kejal Kantarci

P6.322

P6.323

Florbetapir Scanning Excludes Alzheimer’s Disease in a Retired NFL Player with Delayed Cognitive Impairment Effie Mitsis, Silvana Riggio, Emily D’Antonio, Martin Goldstein, Steven DeKosky, Thomas Naidich, Bradley Delman, Josef Machac, Lale Kostakoglu, Gregory Elder, Mary Sano, Samuel Gandy, Wayne Gordon

P6.324

Alzheimer as a Default Mode Network Disease: A Grey Matter, Functional and Structural Connectivity Study  Marcio Balthazar, Marina Weiler, Brunno Campos, Thiago Rezende, Benito Damasceno, Fernando Cendes

P6.325 (18F)FDG PET Evidence of

PIB-Positive PET in Individuals with Early- But Not Late-onset Frontotemporal Dementia  Eric Brown, Ariel Graff-Guerrero, Sylvain Houle, Alan Wilson, Zahinoor Ismail, Bruce Pollock, Benoit Mulsant, David Tang-Wai, Nicolaas Verhoeff, Morris Freedman, Romina Mizrahi, Tiffany Chow

P6.332

P6.327

P6.333

Cavum Septum Pellucidum in Symptomatic Retired Pro-football Players  Raquel Gardner, Christopher Hess, Katherine Possin, Brendan Cohn-Sheehy, Joel Kramer, Mitchel Berger, Bruce Miller, Kristine Yaffe, Gil Rabinovici

P6.328

Reliable Detection of Striatal Amyloid with (18F) Flutemetamol: Validation with Postmortem Histopathology Thomas Beach, Dietmar Thal, Adrian Smith, Chris Buckley

P6.329

Progressive Hippocampus Atrophy in Persons with Mild Cognitive Impairment: A Longitudinal MRI Study  Iryna Lobanova, Amna Sohail, Malik Adil, Adnan Qureshi

P6.330 WITHDRAWN P6.331

Pathologic validation of the EADC-ADNI Harmonized Hippocampal Protocol  Liana Apostolova, Chris Zarow, Kristina Biado, Sona Babakchanian, Marina Boccardi, Johanne Somme, Hedieh Honarpisheh, Anna Blanken, Jenny Brook, Spencer Tung, Denise Ng, Jeffrey Alger, Harry Vinters, Martina Bocchetta, Martina Bocchetta, Henri Duvernoy, Clifford Jack, Giovanni Frisoni

Dementia with Lewy bodies: Pathological Basis of the Cingulate Island Sign  Jonathan Graff-Radford, Melissa Murray, Val Lowe, Bradley Boeve, Tanis Ferman, Scott Przybelski, Timothy Lesnick, Matthew Senjem, Jeffery Gunter, Glenn Smith, David Knopman, Clifford Jack, Dennis Dickson, Ronald Petersen, Kejal Kantarci Progressive Hippocampus Atrophy in Persons with Alzheimer’s Disease: A Longitudinal MRI study Iryna Lobanova, Amna Sohail, Malik Adil, Aveen Saed, Adnan Qureshi

P6.334

Genetic Variation Within the Oxidative Phosphorylation Pathway in Stroke and Alzheimer’s Disease  Alessandro Biffi, Mert Sabuncu, Rahul Desikan, Schmansky Nick, David Salat, Jonathan Rosand, Christopher Anderson

Epilepsy and Clinical Neurophysiology: Autoimmune Epilepsy, Intraoperative Monitoring, and Corticography P6.335

Stereo-electroencephalography Versus Subdural Grids and Depth Electrode Placements: When to Use Which? Adetoun Abisogun, Zianka Fallil, Ashesh Mehta, Cynthia Harden

P6.336

Critical Intraoperative Neurophysiologic Monitoring (IONM) Changes Associated with Patient Positioning Maneuvers  Leslie Lee, Sungho Cho, Viet Nguyen, John Ratliff, Jongsoo Park, Jaime Lopez

P6.337

Does Intraoperative Neurophysiologic Monitoring (IONM) Cause Delays in Surgical Cases? Forough Ghavami, Viet Nguyen, Scheherazade Le, Leslie Lee, Charles Cho, Richard Jaffe, Jaime Lopez

P6.338

Fingerprinting Method for Identifying Spatiotemporal-Frequency Motifs in Electrocorticographic Data. Dan Bernardo, Tim Pluta, Hae Won Shin

P6.339

Post Resection Electrocorticography Predicts Seizure Outcome—a Multivariate Logistic Analysis  Sonia Krish, Omotola Hope, Giridhar Kalamangalam, Jeremy Slater, Nitin Tandon

P6.340

The Predictive Value of Electrocorticography in Patients with Mesial Temporal Lobe Epilepsy Undergoing Selective Amygdalohippocampectomy Aline Herlopian, L Greenfield, Bashir Shihabuddin

P6.341

Refractory Status Epilepticus: a Report of Two Cases to Illustrate the Significance of GAD Antibody Ayaz Khawaja, Amy Amara

P6.342

NMDA Receptor Encephalitis Presenting as Partial Status Epilepticus. Case Report and Discussion Simona Proteasa, Josiane LaJoie, Joseph Maytal

P6.343

Is Rasmussen’s Encephalitis a NMDA Encephalitis? A Case Report and Review of Literature  Simona Proteasa, Lines Vargas Collado, Shefali Karkare

P6.344

Intravenous Immunoglobulin Therapy for Late-Stage Rasmussen’s Encephalitis: Long-Term Seizure Freedom  Rahul Dave, Enrique Serrano

Thursday May 1

Atypical Medial Temporal Lobe Dysfunction in Prodromal Alzheimer’s Disease Chiara Cerami, Pasquale Della Rosa, Alessandra Dodich, Giuseppe Magnani, Alessandra Marcone, Andrea Falini, Stefano Cappa, Daniela Perani

P6.326

2015 Education Course Proposal Process 2015 Annual Meeting: Washington, DC

The AAN invites you to submit an Education Program suggestion for May 16, 2014. To submit your proposal, please visit the 67th Annual Meeting. Proposals for new programs are due by AAN.com/view/SearchAM.



Fast, Easy Registration Online  ·  AAN.com/view/AM14 111



Thursday, May 30

Current as of 2/13/2014

Frontiers in Neuroscience Plenary Session

9:00 a.m.–12:00 p.m.

F ocuses on translational research related to clinical issues of importance. Six physician scientists outline their recent research findings, along with the clinical implications. Moderator: Massimo Pandolfo MD Member, Science Committee; Chair, International Subcommittee

Tissue Environments for Brain Repair

Using Fixed Circuits to Generate Flexible Behaviors

S. Thomas Carmichael, MD, PhD David Geffen School of Medicine at UCLA, Los Angeles, CA

Cori Bargmann, PhD Rockefeller University, New York, NY

Opportunities and Challenges of Robot Assisted and Facilitated Neurorecovery

Advances in Mapping Human Brain Connectivity: The Human Connectome Project

Albert Lo, MD, PhD Brown University, Providence VA Medical Center, Providence, RI

Bruce R. Rosen, MD, PhD Harvard Medical School, Boston, MA

The Nightlife of Astrocytes

Network-based Neurodegeneration

Maiken Nedergaard, MD, DMSc University of Rochester Medical Center, Rochester, NY

William Seeley, MD UCSF, San Francisco, CA

For Full Abstracts and Bios for Plenary Speakers Visit AAN.com/view/SearchAM

112

2O14 Scientific Abstract Listing and Annual Meeting Information

American Academy of Neurology and American Brain Foundation

2O14 Awards Luncheon Join AAN leaders for lunch honoring top accomplishments in the field from enterprising high school students to world-renowned researchers. Seating is limited.

Wednesday, April 30 12:00 p.m.-1:30 p.m.

Public Leadership in Neurology Award Winner Ben Utecht NFL star-turned-singer Ben Utecht will receive the American Brain Foundation’s 2014 Public Leadership in Neurology Award for his commitment to spreading the word about how concussions and traumatic brain injury have affected his life. After winning a Super Bowl ring in 2007, his career ended unexpectedly after a traumatic brain injury in 2009. Many saw this as an ending, but Ben saw an opportunity to pursue another lifelong passion—singing.

April 26 – May 3, 2014 Philadelphia, PA



Thursday, May 1 S44 MS and CNS Inflammatory Disease: Neuroimaging I

S45 Cerebrovascular Disease and Interventional Neurology: Rehabilitation, Recovery, and Complications

1:00 p.m. S44.001 Leptomeningeal Contrast Enhancement in Multiple Sclerosis: a Possible Marker of Inflammation in the Subarachnoid Space   Daniel Reich, Anuradha Rao, Luisa Vuolo, Martina Absinta, Govind Nair, John Butman, Irene Cortese

1:00 p.m. S45.001 Stroke Survivors with Aphasia May Overestimate Communication Skills: Survivor Versus Caregiver Report   Vahid Behravan, James Maniscalco, Darlene Williamson, A. Barrett

1:15 p.m. S44.002 Direct MRI Detection of Impending Plaque Development in MS   Martina Absinta, Pascal Sati, Govind Nair, Massimo Filippi, Irene Cortese, Daniel Reich

1:15 p.m. S45.002 The Association Between Meeting Life’s Simple 7 Goals and Mortality After Stroke in the US   Michelle Lin, Daniela Markovic, Bruce Ovbiagele, Amy Towfighi

1:30 p.m. S44.003 In Vivo PET Imaging of Activated Microglial Cells Can Be Used to Differentiate Between Inactive and Active Chronic Lesions in Progressive Multiple Sclerosis   Laura Airas, Eero Rissanen, Jouni Tuisku, Alex Dickens, Daniel Anthony, Juha Rinne

1:30 p.m. S45.003 The Amphetamine-Enhanced Stroke Recovery (AESR) Trial: Primary Part 1 Results   Larry Goldstein, Meheroz Rabadi, Michael Reding, Laura Lennihan, David Good, Alexander Dromerick, John Pura, Gregory Samsa

1:45 p.m. S44.004 Myelin-Related Advanced MRI Demonstrates Different Degrees of Change Between Various White Matter Tracts in MS   Shannon Kolind, Irene Vavasour, Alexander Rauscher, Andrew Riddehough, David Leppert, Nicolas Seneca, Yinshan Zhao, Roger Tam, A. MacKay, David Li, Anthony Traboulsee

1:45 p.m. S45.004 Hospital Factors Associated with Feeding Tube Placement for US Stroke Inpatients   Benjamin George, Adam Kelly, Eric Schneider, Robert Holloway

2:00 p.m. S44.005 Longitudinal Changes in Myelin Water Fraction in New Multiple Sclerosis Lesions   Wendy Vargas, Elizabeth Monohan, Sneha Pandya, Michael Dayan, Thanh Nguyen, Ashish Raj, Susan Gauthier 2:15 p.m. S44.006 Ultra-high-resolution Imaging of Brain-free Water for Rapid Atrophy Assessment in MS   Katherine Gao, Govind Nair, Irene Cortese, Alan Koretsky, Daniel Reich 2:30 p.m. S44.007 Intracortical Laminar Pathology in the Motor Cortex Is Associated with Tractographically Connected White Matter Injury in Multiple Sclerosis: a Multimodal 7T and 3T MRI Study.   Céline Louapre, Sindhuja Govindarajan, Costanza Giannì, Julien Cohen-Adad, Sean Tobyne, Revere Kinkel, Caterina Mainero

114

2:00 p.m. S45.005 Utilization of In-hospital Palliative Care for Ischemic Stroke Deaths in United States   Shah Shreyansh, Yogesh Moradiya, Santosh Murthy 2:15 p.m. S45.006 Subjective Judgments of Physicians and Nurses Are More Accurate Than Formal Clinical Scales in Predicting Functional Outcome After Intracerebral Hemorrhage   David Hwang, Cameron Dell, Mary Sparks, Tiffany Watson, Carl Langefeld, Mary Comeau, Jonathan Rosand, Thomas Battey, Sebastian Koch, Mario Perez, Michael James, Jessica McFarlin, Jennifer Osborne, Daniel Woo, Steven Kittner, Kevin Sheth 2:30 p.m. S45.007 Efficacy of Single and Multiple Injections of Human Umbilical Tissue-Derived Cells Following Experimental Stroke in Rats   Amjad Shehadah, Jieli Chen, Brian Kramer, Alex Zacharek, Yisheng Cui, Cynthia Roberts, Mei Lu, Michael Chopp

1:00 p.m.–2:45 p.m. S46 Neuromuscular Disease: Genetics, Pathogenesis, and Measures 1:00 p.m. S46.001 Exome Sequencing Identifies PINCH2 Mutations in Early Onset Autosomal Recessive LGMD with Severe Cardiomyopathy and Triangular Tongues   Jodi Warman Chardon, Amanda Smith, John Woulfe, Kawan Rakhra, Elena Pena Fernandez, Chandree Beaulieu, Jeremy Schwartzentruber, Cynthia Hawkins, Matthew Harms, Mei Zhang, Jacek Majewski, Dennis Bulman, Kym Boycott, David Dyment 1:15 p.m. S46.002 Founder Mutation in the γ-Sarcoglycan Gene Causes Milder Phenotype of Limb-Girdle Muscular Dystrophy Type 2C (LGMD2C) in the Hispanic Population of Puerto Rico   Samiah Al-Zaidy, Vinod Malik, Kelley Kneile, Xiomara Rosales, Julie Gastier-Foster, Peter Kang, Basil Darras, Louis Kunkel, Steven Moore, Robert Pyatt, Jerry Mendell 1:30 p.m. S46.003 Novel Mutation in VCP Causes Charcot-Marie-Tooth Type 2 (CMT2) Phenotype   Shawna Feely, Michael Gonzalez, Chris Weihl, Michael Shy, Stephan Zuchner 1:45 p.m. S46.004 Ethoxyquin Prevents Development of Neuropathy in Rodent Models of Diabetic Peripheral Neuropathy and HIV-Associated Neuropathy   Ahmet Hoke, Nicole Reed, Jing Zhu 2:00 p.m. S46.005 Monocarboxylate Transporter 1 (MCT1) Is Critical for Regeneration in Peripheral Nerves   Brett Morrison, Akivaga Tsingalia, Sylvain Lengacher, Luc Pellerin, Pierre Magistretti, Jeffrey Rothstein 2:15 p.m. S46.006 Amyotrophic Lateral Sclerosis Quality Measures   Robert Miller, Benjamin Brooks, Rebecca SwainEng, Robert Basner, Gregory Carter, Patricia Casey, Adam Cohen, Richard Dubinsky, Dallas Forshew, Carlayne Jackson, Edward Kasarskis, Nicholas Procaccini, Mohammed Sanjak, Fredrik Tolin 2:30 p.m. S46.007 NeuroBANK™ and Global Unique Patient Identifier Allow for Secure Collaboration, Data Aggregation and Sharing   Alexander Sherman, Igor Katsovskiy, Roger Selsov, Ervin Sinani, Jason Walker, James Berry, Jonathan Katz, Merit Cudkowicz

2O14 Scientific Abstract Listing and Annual Meeting Information

S47 Movement Disorders: Huntington's Disease, Ataxia, and Wilson's Disease 1:00 p.m.  Presentation of Jon Stolk Award in Movement Disorders for Young Investigators Recipient: Alice Chen-Plotkin, MD Philadelphia, PA

1:15 p.m. S47.002 The Huntington’s Disease-Behavioral Questionnaire (HD-BQ): a New Screening Tool for Behavioral Disturbances in HD   Jody CoreyBloom, Andrew Herndon, Elizabeth Breen, Sean Huynh, Paul Gilbert 1:30 p.m. S47.003 Selected Health and Life Style Factors and Time to Phenoconversion in Huntington’s Disease   Caroline Tanner, Karen Marder, Shirley Eberly, Kevin Biglan, David Oakes, Ira Shoulson 1:45 p.m. S47.004 Safety and Tolerability of Selisistat for the Treatment of Huntington’s Disease: Results from a Randomized, Double-Blind, Placebo-Controlled Phase II Trial   Ralf Reilmann, Ferdinando Squitieri, Josef Priller, Carsten Saft, Caterina Mariotti, Sigurd Suessmuth, Andrea Nemeth, Sarah Tabrizi, Oliver Quarrell, David Craufurd, Hugh Rickards, Anne Rosser, Darpo Borje, Tessari Michaela, Szynol Angieszka, David Fischer, Douglas Macdonald, Ignacio Munoz-Sanjuan, Robert Pacifici, Chris Frost, Ruth Farmer, Bernhard Landwehrmeyer, Goran Westerberg 2:00 p.m. S47.005 A Novel Familial Mutation in the CACNA1A Gene Associated with an Episodic Ataxia Type 2 Phenotype   Jessica Tate, Mustafa Siddiqui, Ihtsham Haq 2:15 p.m. S47.006 Treatment of Spinocerebellar Ataxia Type 2 (SCA2) with MOE Antisense Oligonucleotides   Daniel Scoles, Gene Hung, Lance Pflieger, Khanh Thai, Frank Bennett, Stefan Pulst 2:30 p.m. S47.007 Complete Neurological Recovery in Wilson Disease: Experience with 100 Consecutive Patients Seen from 2005-2013   Annu Aggarwal, Mohit Bhatt

S48 Aging, Dementia, and Cognitive and Behavioral Neurology: MRI Imaging 1:00 p.m. S48.001 Focal Cortical Patterns in Hippocampal Sparing AD Reveal Significant Clinical Differences   Melissa Murray, Ranjan Duara, Ashley Cannon, Amanda Liesinger, Owen Ross, Ronald Petersen, Bradley Boeve, Neill Graff-Radford, Dennis Dickson 1:15 p.m. S48.002 Subcortical Rather Than Cortical Microinfarcts Are More Strongly Associated with Cerebral Cortical Atrophy on MRI   Ling Zheng, Harry Vinters, Wendy Mack, Michael Weiner, Helena Chui 1:30 p.m. S48.003 Microinfarcts Are as Strongly Related to Dementia as Tangles in the Oldest-Old: the 90+ Study   Maria Corrada, Claudia Kawas, Szofia Bullain, Joshua Sonnen 1:45 p.m. S48.004 Pattern of Brain Atrophy Rates on Serial MRI in Autopsy-confirmed Dementia with Lewy Bodies   Zuzana Nedelska, Tanis Ferman, Bradley Boeve, Scott Przybelski, Timothy Lesnick, Melissa Murray, Jeffrey Gunter, Matthew Senjem, Glenn Smith, Yonas Geda, Jonathan Graff-Radford, David Knopman, Ronald Petersen, Clifford Jack, Joseph Parisi, Dennis Dickson, Kejal Kantarci 2:00 p.m. S48.005 ApoE4 Worsens Hippocampal CA1 Apical Neuropil Atrophy and Episodic Memory   Geoffrey Kerchner, Daniela Berdnik, Jadon Shen, Jeffrey Bernstein, Michelle Fenesy, Gayle Deutsch, Tony Wyss-Coray, Brian Rutt 2:15 p.m. S48.006 The EADC-ADNI Harmonized Protocol for Hippocampal Segmentation on Magnetic Resonance: Evidence of Validity   Marina Boccardi, Martina Bocchetta, Clarissa Ferrari, Simon Duchesne, Clifford Jack, Giovanni Frisoni 2:30 p.m. S48.007 Genetic and Neuroanatomic Associations in Sporadic Frontotemporal Lobar Degeneration   Corey McMillan, Jon Toledo, Brian Avants, Philip Cook, Elisabeth Wood, Eunran Suh, David Irwin, John Powers, Christopher Olm, Lauren Elman, Leo McCluskey, Gerard Schellenberg, Virginia Lee, John Trojanowski, Vivianna Van Deerlin, Murray Grossman

Scientific Sessions 1:00 p.m. S49.001 Prospective Study of Cost of Care at Multidisciplinary Centers Adhering to AAN Amyotrophic Lateral Sclerosis (ALS) Practice Parameters   Rup Tandan, Kevin Boylan, Todd Levine, Catherine Lomen-Hoerth, Peter Callas, Kimberly Maginnis, Mary Lyon 1:15 p.m. S49.002 Redesigned Stroke Care for a Value Based World: Better Outcomes, Lower Spending   Waimei Tai, Lucy Kalanithi, Jared Conley, Arnold Milstein 1:30 p.m. S49.003 Readmission Rates to the UAMS Inpatient Neurology Services   Jay Hinkle, Archana Hinduja 1:45 p.m. S49.004 Social Media and Multiple Sclerosis: An Italian Experience   Luigi Lavorgna, Manuela De Stefano, Daniela Buonanno, Eboli Simone, Gallo Antonio, Simona Bonavita, Gioacchino Tedeschi 2:00 p.m. S49.005 Appropriateness of Dopamine Antagonist Prescribing in Hospitalized Patients with Dopamine Requiring Diseases After Implementation of an Automated Prescribing Alert System   Marie Morris, Allison Willis, Franklin McCann, Angela Birke, Brad Racette 2:15 p.m. S49.006 High Accordance Rate of Neurologist Referrals for Psychogenic Patients with Expert Opinion at the Movement Disorders Screening Clinic at the Human Motor Control Section of the National Institute of Neurologic Disorders and Stroke   Vesper Ramos, Monica Anne Faye Villegas, Alina Esquenazi, Mark Hallett 2:30 p.m. S49.007 Limitations of Quantative EEG Analysis in the Adult ICU.   Mirhan Ozbalik, Victor Gonzalez-Montoya, Soundarya Gowda, Lawrence Morton

S50 Epilepsy and Clinical Neurophysiology (EEG): Electrophysiology, Imaging and Functional Connectivity

S51 Cerebrovascular Disease and Interventional Neurology: Large Vessel Atherosclerotic Disease

1:00 p.m.  Presentation of Founders Award

1:00 p.m.  Presentation of Michael S. Pessin Stroke Leadership Prize

Recipient: Shennan Weiss, MD, PhD New York, NY

1:15 p.m. S50.002 Extra-hippocampal Gray Matter Atrophy in Seizure-free Patients with Temporal Lobe Epilepsy With and Without Hippocampal Sclerosis   Marina Alvim, Ana Coan, Clarissa Yasuda, Brunno Campos, Fernando Cendes 1:30 p.m. S50.003 Resection of Ictal Phase Locked HFOs Is Correlated with Outcome Following Epilepsy Surgery   Shennan Weiss, Robert Connors, Garrett Banks, Guy McKhann Jr, Binsheng Zhao, Christopher Filippi, Ronald Emerson, Andrew Trevelyan, Catherine Schevon 1:45 p.m. S50.004 Human Mesial Temporal Lobe Single Neuron Dynamics During Recruitment into a Generalizing Seizure   Amrit Misra, Xianda Long, Ashwini Sharan, Michael Sperling, Karen Moxon 2:00 p.m. S50.005 Functional Connectivity Between Insula, Hippocampus, and Amygdala Investigated Using Cortico-Cortical Evoked Potentials (CCEPs)   Bilal Zonjy, Ayham Alkhachroum, Emine Kahriman, Nuria Lacuey, Jonathan Miller, Hans Luders 2:15 p.m. S50.006 Graph Theory Based Functional Connectivity in Lateralized Temporal Lobe Epilepsy   Sharon Chiang, John Stern, Jerome Engel, Harvey Levin, Zulfi Haneef 2:30 p.m. S50.007 Physiologic and Cortical Response to Acute Psychosocial Stress in Left Temporal Lobe Epilepsy   Jane Allendorfer, Heidi Heyse, Lucy Mendoza, Jerzy Szaflarski



Recipient: Hooman Kamel, MD New York, NY

1:15 p.m. S51.002 Vascular Inflammation Imaging with 18F-FDG PET/CT for In-Stent Restenosis After Intracranial Stent Deployment in a Swine Model   Zhong-Song Shi, Zhong Liu, Jin-Shan Wang, Dong-Hong Liu, Xin-Chong Shi, Xiang-Song Zhang, De-Ji Chen, Ying Liu, Yan-Qiu Liu, Qing-Yuan Wang, Lei Feng 1:30 p.m. S51.003 Safe Triage to Acute Versus Delayed Carotid Imaging Is Achievable Using ABCD3 Scores   Johansson Elias, Jakob Bjellerup, Per Wester 1:45 p.m. S51.004 Frequency of Occurrence Acute Asymptomatic Ischemic Lesions of Brain After CAS.   I. Sinitsyn 2:00 p.m. S51.005 Effect of Carotid Revascularization Endarterectomy Versus Stenting Trial Results on Performance of Carotid Artery Stent Placement and Carotid Endarterectomy in United States   Farhan Siddiq, Malik Adil, Ahmed Malik, Saqib Chaudhry, Adnan Qureshi 2:15 p.m. S51.006 The Cost Per Stroke Prevented (CPSP) from Symptomatic Carotid Artery Stenosis in Ontario, Canada   David Turkel-Parrella, Airton de Oliveira Manoel, Thomas Marotta, Julian Spears 2:30 p.m. S51.007 Delay in the Diagnosis of Basilar Artery Ischemic Stroke   Joseph Burns, Rima Sestokas, Christopher Carr, Helena Lau, Deborah Green, Anna Marisa Cervantes-Arslanian, Rony Salem, Carlos Kase

S52 General Neurology III 1:00 p.m. S52.001 Intra-spinal Transplantation of Mesenchymal Stem Cell-Neural Progenitor (MSC-NP) in Patients with Amyotrophic Lateral Sclerosis (ALS)   Saeed Shahbeigi, Ehsaun Hamediseresht, Nasser Aghadmi, Reza Bakhshandepour, Abbas Najjari, Forough Nejatollahi, Ghazal Jalilzadeh, Sara Samavati, Maliheh Heydari, Toraj Orang, Somaye Noroozi 1:15 p.m. S52.002 Connecting Invasive and Noninvasive Brain Stimulation   Michael Fox, Randy Buckner, Andres Lozano, Alvaro Pascual-Leone 1:30 p.m. S52.003 Autoimmunity to Inhibitory Synaptic Proteins in Stiff-Person Spectrum of Symptoms   Eugenia MartinezHernandez, Nuria Gresa-Arribas, Mar Petit-Pedrol, Helena Ariño, Albert Saiz, Francesc Graus, Josep Dalmau 1:45 p.m. S52.004 GCH1 Heterozygous Mutation Identified by Whole-ExomeSequencing as a Treatable Condition in a Patient Presenting with Progressive Spastic Paraplegia   Zheng Fan, Robert Greenwood, Ana Felix, Yael ShilohMalawsky, Myra Roche, Kristy Crooks, Jonathan Berg, James Evans 2:00 p.m. S52.005 Confirmed: The Antigen of Paraneoplastic Antibodies Previously Named “anti-Tr” Is Delta/Notch-like Epidermal Growth Factor-related Receptor (DNER)   Maxwell Greene, Yongjie Lai, Josep Dalmau, Eric Lancaster 2:15 p.m. S52.006 Aphasia as a Complication of CD19Targeted Chimeric Antigen Receptor Immunotherapy   Sarah Kranick, Giao Phan, James Kochenderfer, Steven Rosenberg, Avindra Nath 2:30 p.m. S52.007 Does Therapeutic Hypothermia Affect the Prognostic Accuracy of a Clinical Neurological Examination and SSEP?   Dragancea Irina

S53 MS and CNS Inflammatory Disease: Biomarkers and Therapeutic Mechanisms 1:00 p.m. S53.001 Following Anti-CD20 Treatment Immune-Competent B Cells Reoccur in Bone Marrow and Spleen Before They Can Be Detected in Peripheral Blood   Martin Weber 1:15 p.m. S53.002 B Lymphocytes Induce CNS Pathology Involving Reactive Astrogliosis and Oligodendrocyte Loss in a Murine System and in Human Multiple Sclerosis   Leila Jackson, Danielle Harlow, Sean Selva, Tracy Niedzielko, Wendy Macklin, Timothy Vollmer 1:30 p.m. S53.003 Increased CSF Level of Monocyte/ Microgrial Activation Maker in Progressive-Multiple Sclerosis   Mika Komori, Andrew Blake, Elena Romm, Yen-Chih Lin, Bibiana Bielekova 1:45 p.m. S53.004 S1P Receptor Modulation by Fingolimod Promotes Human Oligodendrocyte Progenitor Cell Differentiation Through Cell-Autonomous and Non-Cell Autonomous Mechanisms via ERK1/2 and p38MAPK Activation   Qiaoling Cui, Timothy Kennedy, Guillermina Almazan, Jack Antel 2:00 p.m. S53.005 Chitinase 3-like 1 and Chitinase 3-like 2 as Diagnostic and Prognostic Biomarkers of Multiple Sclerosis   Eric Thouvenot, Geoffrey Hinsinger, Nathalie Galeotti, Nicolas Nabholz, Serge Urbach, Valerie Rigau, Christophe Demattei, Sylvain Lehmann, William Camu, Pierre Labauge, Giovanni Castelnovo, David Brassat, Laplaud DavidAxel, Olivier Casez, Joël Bockaert, Philippe Marin 2:15 p.m. S53.006 Dimethyl Fumarate Utilizes Nrf2-independent and Nrf2dependent Pathways for Immune Modulation   Ulf Schulze-Topphoff, Michel Varrin-Doyer, Kara Pekarek, Robert Scannevin, Scott Zamvil 2:30 p.m. S53.007 Antibodies Against the Inward Rectifying Potassium Channel KIR4.1 Precede the Onset of Multiple Sclerosis   Viola Biberacher, Rajneesh Srivastava, Sudhakar Reddy Kalluri, Lucas Schirmer, Dorothea Buck, Rebecca Selter, Bernhard Hemmer

Fast, Easy Registration Online  ·  AAN.com/view/AM14 115

Thursday May 1

S49 Practice, Policy, and Ethics



Thursday, May 1 I9  Emerging Concepts in Headache Therapy

1:00 p.m.–5:00 p.m.

Coordinators: Andrew H. Ahn, MD, PhD and Morris Levin, MD, FAAN Invited Speaker Session:  1:00 p.m.–3:30 p.m. 1:00 p.m.–1:30 p.m.

Pathophysiology of Migraine: New Therapeutic Targets  Andrew Charles, MD

1:30 p.m.–2:00 p.m.

Critical Challenges in the Diagnosis of Headache  Peter Goadsby, MD, PhD

2:00 p.m.–2:30 p.m.

Opportunities and Controversies in Headache Medicine  Richard B. Lipton, MD, FAAN

2:30 p.m.–3:00 p.m.

How Comorbidities Set the Agenda for Headache Therapy  Deborah I. Friedman, MD, FAAN

3:00 p.m.–3:30 p.m.

Neuromodulation: Increasing the Gain on Headache Therapy  Morris Levin, MD, FAAN

Poster Rounds:  3:30 p.m.–4:30 p.m. I9-1.001

Patient Satisfaction with MAP0004: Results of an Optional Survey During a Long-term Open-label Safety Study  Sheena Aurora, Dawn Buse, Biao Lu, Donald Kellerman, Wade Cooper, Shashidhar Kori

I9-1.004 Barriers to Chronic Migraine

I9-1.002 Optical Imaging of Facial

I9-1.005 Bilateral Pain

Perfusion in Migraine  Jonas Peterson, Lindsay Hunter, Melissa Cortez, Jeremy Theriot, KC Brennan

I9-1.003 Therapeutic Efficacy of

Transcranial Direct Current Stimulation in Trigeminal Neuralgia  Mark Obermann, Vera Bude, Dagny Holle, Tim Hagenacker, H. Diener, Zaza Katsarava

Care: Results of the CaMEO (Chronic Migraine Epidemiology and Outcomes) Study  Dawn Buse, Richard Lipton, Michael Reed, Daniel Serrano, Kristina Fanning, Aubrey Manack Hypersensitivity over the Trigeminal Region and Dental Deafferentations in Patients with Classical Trigeminal Neuralgia  Nathalie Guy, Béatrice Claise, Pierre Clavelou, Radhouane Dallel

I9-1.006 Idiopathic Intracerebral

Hypertension (IIH)/pseudotumor: Removing Less CSF Is Best  Franchesca Fiorito-Torres, Melissa Rayhill, Michael Perloff

I9-1.007 Long Term Therapeutic

Response of Sphenopalatine Ganglion (SPG) Stimulation for Cluster Headache— Pathway CH-1 Study  Miguel Lainez, Rigmor Jensen, Arne May, Charly Gaul, Anthony Caparso, Amy Goodman, Jean Schoenen

I9-1.008 White Matter

Microstructure Abnormalities in Paediatric Migraine Patients: In-Vivo Measures of Brain Hyperexcitability?  Roberta Messina, Maria Rocca, Bruno Colombo, Elisabetta Pagani, Andrea Falini, Giancarlo Comi, Massimo Filippi

I9-1.009 Interictal Reduced

Cranial Parasympathetic Tone in Cluster Headache  Hilde Karen Ofte, Therese von Hanno, Karl Alstadhaug

I9-1.010

Treatment of Withdrawal Headache in Patients with Medication Overuse Headache (MOH): A Randomized, Single-blinded, Placebo Controlled Study  Sabina Cevoli, Giulia Giannini, Valentina Favoni, Elisa Sancisi, Marianna Nicodemo, Stefano Zanigni, Daniela Grimaldi, Giulia Pierangeli, Pietro Cortelli

Data Blitz:  4:30 p.m.–5:00 p.m. 4:30 p.m.

I9-2.001

Mid-life Migraine and Late-life Movement Disorder Symptoms: AGES-Reykjavik Study  Ann Scher, G. Ross, Sigurdur Sigurdsson, Melissa Garcia, Larus Gudmundsson, Sigurlaug Sveinbjornsdottir, Vilmundur Gudnason, Lenore Launer

4:35 p.m.

I9-2.002

Efficacy and Safety of AVP-825, a Novel Breath-Powered™ Powder Sumatriptan Intranasal Treatment, for Acute Migraine  Roger Cady, John Messina, Jennifer Carothers, Ramy Mahmoud

4:40 p.m.

I9-2.003

Characterization of Photosensitivity and Pupil Oscillation Rate in Migraine  Lindsay Hunter, Jonas Peterson, Melissa Cortez, Jeremy Theriot, K.C. Brennan

4:45 p.m.

I9-2.004

4:50 p.m.

I9-2.005

Chronic Migraine with Medication Overuse Is Associated with Low Cognitive Reserve  Marian Gomez Beldarrain, Ane Anton Ladislao, Urko Aguirre Larracoechea, Alberto Cabrera Zubizarreta, Isabel Oroz, Carlos Garcia-Monco Carra Gammacore Device for Treatment of Migraine Attack: Preliminary Data  Licia Grazzi, Susanna Usai, Gennaro Bussone

116

2O14 Scientific Abstract Listing and Annual Meeting Information

Integrated Neuroscience Sessions I10  The Global Burden of Neurological Diseases

1:00 p.m.–5:00 p.m.

Coordinators: Jerome H. Chin, MD, PhD, MPH and Massimo Pandolfo, MD Invited Speaker Session:  1:00 p.m.–3:30 p.m. 1:00 p.m.–1:15 p.m.

Global Health and Neurology  Jerome H. Chin, MD, PhD, MPH; Massimo Pandolfo, MD

1:15 p.m.–1:45 p.m.

Global Epidemiology of Parkinson’s Disease  Walter A. Rocca, MD, MPH

1:45 p.m.–2:15 p.m.

Neurocysticercosis and Epilepsy  Oscar H. Del Brutto MD, FAAN

2:15 p.m.–2:45 p.m.

Cerebrovascular Disease in China  Yi-Cheng Zhu, MD, PhD

2:45 p.m.–3:15 p.m.

Traumatic Brain Injury: The Neglected Global Epidemic  Jerome H. Chin, MD, PhD, MPH

3:15 p.m.–3:30 p.m.

Questions and Answers

Poster Rounds:  3:30 p.m.–4:30 p.m. I10-1.001 Risk Factors for Epilepsy in

Children with HIV/AIDS in Botswana David Bearden, Greg Bisson, Dennis Kolson, Andrew Steenhoff, Sudha Kessler, Dennis Dlugos

I10-1.002 Comparing Cognitive

Screening Tools in a Rural Ecuadorian Population: The Atahualpa Project Clinton Wright, Hannah Gardener, Mauricio Zambrano, Victor Del Brutto, Oscar Del Brutto

I10-1.003 The Risk of Large-artery

I10-1.004 Incidence and Mortality

I10-1.006 Neuro-Developmental

I10-1.005 Prevalence, Incidence and

I10-1.007 Clinical and Bacteriological

of Ischemic Stroke Subtypes in Joinville, Brazil: A Population-based Study Marcos Lange, Norberto Cabral, Carla Moro, Alexandre Longo, Anderson Goncalves, Viviane Zetola, Tatjana Rundek Associations Between APOE Genotype, Cardiovascular Risk Factor and Dementia in Cuban Populations  Jorge Jesús Llibre Guerra, Milagros Guerra, Juan Carlos Llibre Guerra, Juan Jesús Llibre Rodriguéz

Atherosclerotic Stroke Is Proportionally Greater than Cardioembolic Stroke in HIV-infected Individuals Compared to HIVuninfected Controls  Felicia Chow, Richard Price, Priscilla Hsue, Anthony Kim

Disorders in India—From Epidemiology to Public Policy  Donald Silberberg, Narendra Arora, Vinod Bhutani, Maureen Durkin, Shefalli Gulati, Mkc Nair, Jennifer PintoMartin Features of Central Nervous System Tuberculosis in Patients with HIV-Infection in Siberian Region of Russia  Yury Bykov, Tatiana Filippova, Olga Novitskaya

I10-1.009 A Phone App to Diagnose

Epileptic Seizures: A Useful Tool to Reduce the Epilepsy Treatment Gap in Poorer Countries  Victor Patterson, Mamta Singh, Hemav Rajbhandari

I10-1.010 Hypertension in Rural

Uganda: Findings from a Community-Based Screening Project  Jerome Chin

I10-1.008 Stroke Mortality and Its

Predictors in Nigeria: Results of a HospitalBased Study  Kolawole Wahab, Emmanuel Sanya, Babatunde Ademiluyi, Bello Abiodun, Wemimo Alaofin

Data Blitz:  4:30 p.m.–5:00 p.m. I10-2.001

The Association Between Meeting Life’s Simple 7 Goals and Mortality After Stroke in the US  Michelle Lin, Daniela Markovic, Bruce Ovbiagele, Amy Towfighi

4:35 p.m.

I10-2.002

4:40 p.m.

I10-2.003

Variations in Brain Death Declaration: A Worldwide Survey  Sarah Wahlster, Eelco Wijdicks, Pratik Patel, David Greer, Claude Hemphill, Farrah Mateen

Indonesia Stroke Registry  Fenny Yudiarto, Mochammad Machfoed, Amir Darwin, Anam Ong, Muhammad Karyana, Siswanto



4:45 p.m.

I10-2.004

Helping Haiti: Addressing the Burden of Neurologic Disease  Veronica Santini, Anthony Alessi, Elaine Jones, Mill Etienne, Anna Hohler

4:50 p.m.

I10-2.005

Performance of Cerebrospinal Fluid (CSF) Plasmodium falciparum Histidine-Rich Protein-2 (pfHRP-2) in Prediction of Death in Cerebral Malaria  Kiran Thakur, Jimmy Vareta, Kathryn Carson, Terrie Taylor, David Sullivan, Karl Seydel

Fast, Easy Registration Online  ·  AAN.com/view/AM14

117

Thursday May 1

4:30 p.m.



Thursday, May 1 P7  Poster Session VII First Authors stand by Posters from 5:00 p.m.–6:30 p.m

3:00 p.m.–6:30 p.m.

 oster Discussion Session: P Neuromuscular and Clinical Neurophysiology (EMG) II Utilizing a guided tour format, topic experts will lead attendees around the ten posters in the poster discussion session and facilitate questions with poster authors during the 90-minute author stand-by time.

P7.001

Deletion of Sarm1 Gene Protects Against Paclitaxel-induced Peripheral Neuropathy  Ahmet Hoke, Elliot Turkiew, Nicole Reed

P7.002

Frequency and Time to Relapse after Discontinuing 6-month Therapy with Intravenous Immunoglobulin or Methylprednisolone in Chronic Inflammatory Demyelinating Polyradiculoneuropathy Eduardo Nobile-Orazio, Dario Cocito, Stefano Jann, Antonino Uncini, Paolo Messina, Ettore Beghi, Giovanni Antonini, Raffaella Fazio, Francesca Gallia, Angelo Schenone, Ada Francia, Davide Pareyson, Lucio Santoro, Stefano Tamburin, Guido Cavaletti, Fabio Giannini, Mario Sabatelli

P7.003

Sudoscan as a Diagnostic Tool for Diabetic and Idiopathic Peripheral Neuropathy  A. Smith, Margaret Lessard, J. Singleton

P7.004

Defective Muscle Mitochondrial Biogenesis in Spinal Muscular Atrophy.  Dario Ronchi, Michela Ripolone, Emanuele Barca, Angela Berardinelli, Lucia Morandi, Marina Mora, Andreina Bordoni, Francesco Fortunato, Gigliola Fagiolari, Raffaella Violano, Dionis Vallejo, Stefania Corti, Antonio Toscano, Monica Sciacco, Salvatore DiMauro, Giacomo Comi, Maurizio Moggio

P7.005

Genetic Epidemiology of C9ORF72 in ALS: a National Study in Italy  Adriano Chio, Stefania Battistini, Andrea Calvo, Claudia Caponnetto, Francesca Conforti, Massimo Corbo, Fabio Giannini, Jessica Mandrioli, Fabrizio Salvi, Gabriele Mora, Mario Sabatelli, Vincenzo La Bella, Giancarlo Logroscino, Isabella Simone, Maria Monsurrò, Letizia Mazzini, Giuseppe Borghero, Francesco Logullo, Christian Lunetta, Paolo Volanti, Maura Pugliatti, Paola Mandich, Sandra D’Alfonso, Silvana Penco, Marcella Zollino, Maria Murru, Gabriella Restagno

P7.006

Increased Cerebral Oxidative Stress in Amyotrophic Lateral Sclerosis: A 62 Cu-ATSM PET Study  Masamichi Ikawa, Hidehiko Okazawa, Tetsuya Tsujikawa, Tomoko Muramatsu, Toru Kishitani, Tomoko Kamisawa, Akiko Matsunaga, Osamu Yamamura, Tetsuya Mori, Tadanori Hamano, Yasushi Kiyono, Yasunari Nakamoto, Makoto Yoneda

P7.008

P7.007

P7.009

The Diagnostic Value of Diffusion Tensor MRI Metrics in Relation to the MND Phenotype Heterogeneity  Edoardo Spinelli, Federica Agosta, Nilo Riva, Massimiliano Copetti, Sebastiano Galantucci, Adriano Chiò, Stefano Messina, Sandro Iannaccone, Andrea Calvo, Vincenzo Silani, Andrea Falini, Giancarlo Comi, Massimo Filippi

Muscular Dystrophy Association U.S. Neuromuscular Disease Registry—Preliminary Findings  Jodi Wolff, Joline Dalton, Valerie Cwik, Annie Kennedy, Michelle Morgan, Jane Larkindale, Alan Beggs, Joshua Benditt, James Berry, Thomas Crawford, Emily Munson, Rachel Richesson, Jeffrey Rosenfeld, Carly Siskind, Kevin Flanigan The Course and Outcome of Pregnancy in Women with Nondystrophic Myotonias  Yuliya Snyder, Colleen DonlinSmith, Eva Pressman, Emma Ciafaloni

P7.010

Myasthenia and Risk of Cancer: A Population-based Case-control Study  Emil Pedersen, Anton Pottegaard, Jesper Hallas, Soren Friis, Klaus Hansen, Poul Erik Jensen, David Gaist

NEW! e  Poster Session: Neuro-oncology The ePoster session will feature a selection of posters to be presented digitally, rather than in the traditional format. Authors will be able to take advantage of the format to highlight compelling visual features such as images and videos. See poster map on page 47 for location.

P7.011

Differential Sensitivity of Oligodendrocyte Precursor Cells and Microglia to Methotrexate in Grey Versus White Matter  Lauren Wood, Sarah Miller, Hannes Vogel, Michelle Monje

P7.013

P7.012

Functional Expression of K2P Potassium Channels in Tumor Infiltrating Lymphocytes of Malignant Glioma Ole Simon, Thomas Muentefering, Stefan Bittner, Nico Melzer, Heinz Wiendl, Oliver Grauer, Sven Meuth

P7.014

General Neurology VII

P7.024

Polyneuropathy in Multiple Myeloma Patients Correlate with the Presence of Autoantibodies Adam Niezgoda, Slawomir Michalak, Lidia Gil, Mieczyslaw Komarnicki, Wojciech Kozubski Development of a Mouse Model of Leptomeningeal Metastasis  Adrienne Boire, Lisa DeAngelis, Joan Massagué

P7.021

Babinski or Withdrawal? A New Way to Decide  Sayyed Sohrab, Douglas Gelb

P7.022

P7.025

P7.023

Rare Presentation of Eagle’s Syndrome as Bell’s Palsy  Nancy Rosales, Rachana Gandhi, Ramon Lugo

118

Paraneoplastic Neurological Syndromes: A Single Institution 10-Year Case Series  Amy Chan, Joachim Baehring

P7.017

Delayed Diagnosis of Brachial Plexus Neurolymphomatosis in Post-transplant Patient with Diffuse Large B-cell Lymphoma  Milena Stosic, Sudhakar Tummala

P7.015 WITHDRAWN

When the Typical Becomes Atypical: Anti-Ri Antibody Associated Paraneoplastic Syndrome WITHOUT Opsoclonus-Myoclonus  Yadira VelazquezRodriguez, Divpreet Kaur, Aiesha Ahmed

Absent Inferior Vena Cava with Resulting Venous Congestion Causing Intermittent Cauda Equina Dysfunction  Carrie Grouse, Steven Lewis

P7.016

Diagnostic Confusion About a Confused Patient: A Case of Delayed Post-Anoxic Leukoencephalopathy Syndrome  Tammam Dayyoub, Ahmad Riad Ramadan, Panayiotis Mitsias

P7.026

Nutritional Intake and Iron Bioavailability in Adolescents with Postural Tachycardia Syndrome  Imad Jarjour, Keli Hawthorne, Steven Abrams

P7.027

Restoration of Altered Epigenetic Signature by a Quinoline Compound, S4, (2-(2-methylquinolin-4ylamino)-N-phenyl acetamide), Resulting in Inhibition of Alcohol Drinking Tuhin Banerjee

P7.028

Mitochondrial Variants in ALS  Kevin Kenna, Russell McLaughlin, Susan Byrne, Marwa Elamin, Colette Donaghy, Daniel Bradley, Orla Hardiman

P7.029

Refractory IgG4Related Intracranial Hypertrophic Pachymeningitis  Bing Liao, Carlos Kamiya Matsuoka, Xiang Fang, Robert Smith

2O14 Scientific Abstract Listing and Annual Meeting Information

P7.018

Non-Richter’s Transformation CLL in the CNS: A Case Series Varoon Thavapalan, Lawrence Kenyon, Moshe Mizrahi

P7.019

Photodynamic Therapy (PDT) of Brain Tumors  Venu Parachuri, Akshat Katyayan, Harry Whelan

P7.020

Primary Central Nervous System Lymphoma in Rheumatoid Arthritis Treated with Leflunomide  Andrew Bayat, Jeremy Jones, Harris Naina

P7.030

Detecting Malingering: The Honest Palm Sign  David Black

P7.031

Case Report of Weston Hurst Syndrome  Rick Magun, John Provias

P7.032

A Case of PML After Initiation of Brentuximab Vedotin for CD30 Positive Cutaneous T Cell Lymphoma  Judy Jia, Ethan Goldberg, Joseph Berger, Amy Pruitt

Poster Session VII Electroencephalographic and Positron Emission Tomography Correlates in Anti-N-methyl-D-aspartate Receptor Encephalitis  David Benavides, John Probasco, Beatriz Wills, Angela Wabulya, Gregory Bergey, Peter Kaplan

P7.046

P7.034

P7.047

Extra-motor Symptoms in Amyotrophic Lateral Sclerosis. Analysis of 112 Patients  Hector Martinez, Jorge Moreno-Cuevas, María-Teresa GonzalezGarza, Arturo Robles Tenorio, César Escamilla Ocañas, Sergio Salazar Marioni, Ubaldo Martínez

P7.035 Hyperammonemic

Encephalopathy in Late-Onset Ornithine Transcarbamylase (OTC) Deficiency Unmasked by Acetaminophen Overuse  Heeral Mehta, Danyel Tacker, Anne Josiah, Paola Pergami

P7.036

Picture This! A Meta-Analysis Comparing Affective Salience of Words Versus Images  Eithan Kotkowski, Peter Fox

P7.037

The Belgian Neuromuscular Disease Registry, Results of the 2012 Data  Anna Roy, Philip Van Damme, Peter Van den Bergh, Viviane Van Casteren

P7.038

Abnormal Near Field Potentials of Brainstem Origin in Parkinson’s Disease (PD)  Fidias LeonSarmiento, Rosanna Sobota, Richard Doty

P7.039

CXCL10, CCL5 and IL-6 in Cerebrospinal Fluid of Neuropsychologically Unaffected Patients Correlate with Neurofilament H  Simon Faissner, Björn Ambrosius, Norbert Brockmeyer, Gabriele Arendt, Ralf Gold, Thomas Grunwald, Andrew Chan

P7.040

Prevalence and Predictors of Suicidal Ideation in Epilepsy and Multiple Sclerosis  Leah Dickstein, Amy Nowacki, Adele Viguera

Movement Disorders: Deep Brain Stimulation for Parkinson’s Disease P7.041

How Thin Can a Deep Brain Stimulation Lead Be?  Zhe Li, Khong Siong Ng, Yan Ye, Xiaoping Li

P7.042

Wearable Sensors for Quantifying Deep Brain Stimulation Washout Effects on Gait in Parkinson’s Disease  Elizabeth Brokaw, Thomas Mera, David Riley, Benjamin Walter, Alberto Espay, Fredy Revilla, Joseph Giuffrida, Dustin Heldman

P7.043

How Optogenetics Can Help Improve Deep Brain Stimulation for the Motor Symptoms of Parkinson’s Disease  John Eraifej, Hardev Pall

P7.044

Neuronal Oscillation Patterns in the Subthalamic Nucleus in Parkinsonia Patients with Off Dystonia  Ping Zhuang, Mark Hallett, Li Xiaoyu, Yuqing Zhang, Jianyu Li, Yongjie Li

P7.045

Deep Brain Stimulation (DBS) and Oropharyngeal Dysfunction in Parkinson’s Disease (PD): A Case Report  Pichet Termsarasab, Winona Tse

Impedance Changes Occur During Threshold Measurements in Deep Brain Stimulation Patients Stephen Carcieri, Martin Reich, Frank Steigerwald, Michael Barbe, Ljubomir Manola, Lars Timmermann, Jens Volkmann Atrophy and the Emergence of Induced Side Effects in Deep Brain Stimulation  Daniel Martinez-Ramirez, Takashi Morishita, Pam Zeilman, Michael Okun

P7.048

Comorbidities and the Outcome of Deep Brain Stimulation Surgery in Parkinson’s Disease Faisal Alsallom, Hesham Abboud, Gencer Genc, Srivadee Oravivattanakul, Anwar Ahmed, Scott Cooper, Michal Gostkowski, Andre Machado, Hubert Fernandez

P7.049

A Multiple-Target DBS Strategy for Parkinson’s Disease. MasaAki Higuchi, Takashi Morishita, Kelly Foote, Kelsey Nestor, Justin Hillard, Michael Okun

P7.050

Deep Brain Stimulation of the Nucleus Accumbens Has Positive Effects on Parkinson’s Disease-related Apathy Nolan Williams, Baron Short, Emily Williams, Alexandra Jeffery, Suzanne Kerns, Gregory Sahlem, Colleen Hanlon, Gonzalo Revuelta, Istvan Takacs, Mark George

Movement Disorders: Surgical Approaches to Parkinson’s Disease P7.051

Acute Lower Urinary Tract Dysfunction After Bilateral STN Deep Brain Stimulation Surgery for PD: Case Reports and Literature Review  Richard Salazar, Toby Chai, Paul Fishman, Howard Eisenberg, Stephen Reich

P7.052

Determinants of the Frequency of Post-Operative DBS Office Visits  Justin Martello, Melissa Armstrong, Ann Gruber-Baldini, Erik Barr, Stephen Reich, Paul Fishman, Lisa Shulman

P7.053

Contextual Regulation of Simple Decisions in Parkinson’s Disease: Effects of STN-DBS and L-Dopa Miguel Ulla, Philippe Domenech, Valentin Wyart, Laetitia Silvert, Jean Claude Dreher, Franck Durif

P7.054

Interleaving Could be a Better Programming Technique for Parkinson’s Disease and Dystonia Patients Denny Reyes, Michelle Ferreira, Nestor GalvezJimenez, Tarannum Khan

P7.058

Impact of Socioeconomic Status on Outcome of Deep Brain Stimulation Surgery for Parkinson’s Disease  Gencer Genc, Hesham Abboud, Srivadee Oravivattanakul, Faisal Alsallom, Nicholas Thompson, Scott Cooper, Michal Gostkowski, Andre Machado, Hubert Fernandez

P7.059

Effect of Dorsal and Ventral Subthalamic Nucleus Deep Brain Stimulation on Actual and Perceived Sense of Postural Balance  Travis Larsh, Jonathan Eskenazi, Enrique Urrea Mendoza, Ashutosh Mani, Amit Bhattacharya, Andrew Duker, Cyndy Cox, Maureen Gartner, Fredy Revilla

P7.060

Dorsal and Ventral Subthalamic Nucleus Deep Brain Stimulation Induced Cerebral Blood Flow and Motor Responses  Mwiza Ushe, Meghan Campbell, Samer Tabbal, Morvarid Karimi, Johanna Hartlein, Tamara Hershey, Joel Perlmutter

Movement Disorders: Dystonia Treatment



Movement Disorders: Treatment of Parkinson’s Disease and Other Disorders P7.070

Mayo Clinic Florida Collection of Human Skin Fibroblast Cultures from Patients with Hereditary Neurodegenerative Disorders Zbigniew Wszolek, Pawel Tacik, Shinsuke Fujioka, Audrey Strongosky, Jing Zhao, Takahisa Kanekiyo, Guojun Bu

P7.071

P7.072

Cervical Dystonia Patient Registry for Observation of OnabotulinumtoxinA Efficacy (CD PROBE): Treatment Patterns and Subject Disposition  P. Charles, Joseph Jankovic, Cynthia Comella, Mark Stacy, Marc Schwartz, Aubrey Manack, Mitchell Brin

P7.063 ANCHOR-CD

(AbobotulinumtoxinA Neurotoxin: Clinical and Health Economics Outcomes Registry in Cervical Dystonia): A Multicenter, Observational Study of Dysport in Cervical Dystonia: Baseline Data and Cycle One Efficacy Data  Daniel Truong, Richard Trosch, Cynthia Comella, Jack Chen, Dominic Marchese, Chandra Abbott, Wes Cetnarowski, Alberto Espay

P7.064

Clinical Audit of the Efficacy of Xeomin Against Dysport for the Treatment of Dystonia  Daveena Meeks, Christopher Clough

P7.065

P7.066

Globus Pallidus Versus Subthalamic Nucleus Deep Brain Stimulation For Parkinson’s Disease: A Meta-Analysis  Michele Tagliati, Valentina Pecoraro, Giuseppe Rengo, Cristina Motto, Lorenzo Moja, Gennaro Pagano

Treatment Outcomes in Cervical Dystonia Patient Registry for Observation of OnabotulinumtoxinA Efficacy (CD PROBE)  Joseph Jankovic, Charles Adler, P. Charles, Cynthia Comella, Mark Stacy, Marc Schwartz, Aubrey Manack, Mitchell Brin

P7.062

P7.056

P7.057

P7.069

Response to IncobotulinumtoxinA After Resistance to OnabotulinumtoxinA and RimabotulinumtoxinB  Vesper Ramos, Barbara Karp, Codrin Lungu, Katharine Alter, Mark Hallett

P7.061

Concurrent Bilateral Vim and STN DBS in a Patient with ET/ PD  Subhashie Wijemanne, Olga Waln, Joohi Jimenez Shahed Comparison of Screening Tools for Assessing Deep Brain Stimulation Candidacy in Parkinson Disease Kelvin Chou, Robert Coleman, Parag Patil, Vikas Kotagal

Stability of Botulinum Toxin A Dosage Over Time in Patients with Hemifacial Spasm, Blepharospasm and Cervical Dystonia/Torticollis. Shira McMahan, Denny Reyes, Tarannum Khan

Changes in Troublesome Dyskinesia and its Relationship with Dose in Advanced Parkinson’s Disease Patients Treated with Levodopa-Carbidopa Intestinal Gel Infusion  Angelo Antonini, Victor Fung, James Boyd, John Slevin, Coleen Hall, Jordan Dubow, Krai Chatamra, Janet Benesh

The Retrospective Evaluation of the Dose of IncobotulinumtoxinA and OnabotulinumtoxinA for the Clinical Management of Cervical Dystonia and Blepharospasm: TRUDOSE Pilot Study  Charalampos Tzoulis, Ruth Kent, Adrian Robertson, John Maltman, Chris Purdy, Raf Magar

P7.055

P7.068

Deep Brain Stimulation In Patients with Primary Dystonia with GNAL Mutation: A Case Series  Harini Sarva, Richard Trosch, Amanda Glickman, Deborah Raymond, Laurie Ozelius, Susan Bressman, Rachel Saunders-Pullman

P7.067

Patient experience of Botulinum toxin injections for dystonia and hemifacial spasm: knowledge of diagnosis and treatment  David Grosset, Elaine Tyrrell, Katherine Grosset, Donald Grosset

Apomorphine Improves Morning Akinesia in Parkinson’s Disease: Interim Analysis of the AM-IMPAKT Trial  Stuart Isaacson, William Ondo, Fernando Pagan

P7.073

Approach to Treatment of Depression in Parkinson’s Disease: Results from NPF-QII  Peter Schmidt, Mark Guttman, Laura Marsh, John Nutt, Tanya Simuni, Eugene Nelson, Jorge Zamudio, Michael Okun

P7.074

Pathophysiological Decrease in the Regional Cerebral Blood Flow in Pure Autonomic Failure with Lewy Body  Tomoko Kamisawa, Masamichi Ikawa, Yuki Saito, Tomoko Muramatsu, Akiko Matsunaga, Osamu Yamamura, Tadanori Hamano, Shigeo Murayama, Yasunari Nakamoto, Hidehiko Okazawa, Makoto Yoneda

P7.075

Complicated Hereditary Paraplegia with Novel B4GALNT1 Mutations Expanding, the Phenotype and Genotype  Saeed Bohlega, Salma Wakil, Dorota Monies, Edward Cupler, Layla Bastaki, Brian Meyer

P7.076

Spinal Cord Atrophy in Hereditary Spastic Paraplegia Caused by SPG4 Mutations  Lucas Branco, Lamas Gustavo, Felipe Bergo, Iscia Lopes-Cendes, Marcondes Franca, Jr.

P7.077

Cerebral Damage in SPG4Hereditary Spastic Paraplegia (HSP): a VBM Study  Gustavo Lamas, Cynthia Bonilha Da Silva, Thiago Rezende, Iscia Lopes-Cendes, Marcondes Franca, Jr.

P7.078

A Novel Objective Brain MRI Assessment Scale for Wilson disease (MAS for WD)  Annu Aggarwal, Mihir Munshi, Darshana Sanghvi, Amruta Ravan, Saloni Parekh, Pooja Rane, Mohit Bhatt

Fast, Easy Registration Online  ·  AAN.com/view/AM14

119

Thursday May 1

P7.033



Thursday, May 1 P7.079

Dystonia in Machado-Joseph Disease (MJD/SCA3) Is Associated with Thalamic and Brainstem Atrophy Alberto Martinez, Marcelo Nunes, Thiago Rezende, Rachel Guimarães, Anelyssa D’Abreu, Iscia Lopes-Cendes, Marcondes Franca, Jr.

Movement Disorders: Parkinson’s Disease Therapy P7.080

IPX066 Dose Conversion from Immediate-Release Carbidopa-Levodopa, Carbidopa-Levodopa+Entacapone, and Controlled-Release Carbidopa-Levodopa in Patients with Advanced Parkinson’s Disease (PD)  Ann Hsu, Sarita Khanna, Sherron Kell, Robert Rubens, Suneel Gupta

P7.081

Long-term Safety and Maintenance of Efficacy from an Openlabel Extension of the Double-blind Pivotal Study of Levodopa-carbidopa Intestinal Gel (LCIG) in Advanced Parkinson’s Disease Patients  Hubert Fernandez, Rejko Krueger, John Slevin, Coleen Hall, Susan Eaton, Jordan Dubow, Krai Chatamra, Janet Benesh

P7.082

Improved Motor Performance Associated with Smoother Levodopa Time-Concentration Profiles with DM-1992, a Gastroretentive, Extendedrelease Carbidopa/Levodopa Tablet, in Patients with Advanced Parkinson’s Disease  Leonard Verhagen Metman, Natividad Stover, Cuiping Chen, Verne Cowles, Michael Sweeney

P7.083

Safety Analyses from Openlabel Clinical Trials of Levodopa-Carbidopa Intestinal Gel in Patients with Advanced Parkinson’s Disease: Events Not Related to Device or Procedure  Anthony Lang, Sylvain Chouinard, Cindy Zadikoff, Weining Robieson, Jordan Dubow, Krai Chatamra, Janet Benesh

P7.084

OPTIPUMP: Different Treatment Strategies Using Continuous Apomorphine Pump Therapy in Parkinsonian Patients and Their Influence on Patient Quality of Life. A French 6 Month, 145 Patients, Propective, Multicentre, Observational Study Sophie Drapier, Marc Verin, David Devos, Alexandre Eusebio, Emmanuel Roze, Bertrand Degos, Caroline Moreau, Jean Azulay, Francois Viallet, Luc Defebvre, Christine BrefelCourbon, Christine Tranchant, Valérie Fraix, Sébastien Woynar, David Andrieu, Adrien Borsik, Laetitia Mauger, Franck Durif

P7.085

Gastrointestinal Safety of the Levodopa-Carbidopa Intestinal Gel Delivery System in Treating Advanced Parkinson’s Patients  Michael Epstein, David Johnson, Robert Hawes, Nathan Schmulewitz, Arvydas Vanagunas, Susan Eaton, Krai Chatamra, Weining Robieson, Janet Benesh

P7.086

A Novel Approach to Treating Impulse Control Disorders (ICDs) in Parkinson’s Disease (PD)—a Case Series  John Liang, Mark Groves, Vicki Shanker

120

P7.087

Phase-3 Clinical Trials of Adjunctive Therapy with Preladenant, an Adenosine 2a Antagonist, in Patients with Parkinson’s Disease  Robert Hauser, Fabrizio Stocchi, Olivier Rascol, Susan Huyck, Xianwei Ha, Rachel Capece, Kenneth Wolski, Tony Ho, Peter Sklar, Christopher Lines, David Michelson, David Hewitt

P7.088

Post-hoc Analyses of Phase-3 Data with Preladenant, an Adenosine 2a Antagonist, in Patients with Parkinson’s Disease  Olivier Rascol, Robert Hauser, Fabrizio Stocchi, Xianwei Ha, Rachel Capece, Kenneth Wolski, Tony Ho, Peter Sklar, Christopher Lines, David Michelson, David Hewitt, Susan Huyck

Neuromuscular Disease: Therapy P7.089 WITHDRAWN P7.090

The Effect of Intravenous Immunoglobulin on Regulatory T Cells and Disability Progression in Patients with Chronic Inflammatory Demyelinating Polyradiculoneuropathy  Jason Thonhoff, Luis Lay, Sharon Halton, David Beers, Ericka Simpson

P7.091

Anti-TNF Alpha-induced Neuropathies  Pinelopi Tsouni, Olivier Bill, David Benninger, Francois Ochsner, Thierry Kuntzer

P7.092

Multicentre, Randomised, Open-label Trial to Compare Efficacy and Tolerance of Prednisone and IVIG in Patients with CIDP on a One-year FollowUp  Jean-Philippe Camdessanche, Karine Ferraud, Emmeline Lagrange, Karine Viala, Victor Chan, Nathalie Guy Renouil, Sarah Louis Leonard, Andoni Echaniz-Laguna, Gerard Besson, Francoise Bouhour, Emilien Delmont, Agnes Fromont, Julien Gallard, Armelle Magot, Guillaume Nicolas, David Uzenot, Blanc-Lassere Karine, Tanya Stojkovic, Sandrine Wiertlevski, Boutte Celia, Jean-Christophe Antoine

P7.093

Small Fiber Neuropathy in Sarcoidosis: The Cleveland Clinic Experience  Zubair Ahmed, Jinny Tavee, Daniel Culver, Joseph Parambil

P7.094

Effect of Agmatine Sulfate on Neuropathic Pain  Vahid Tohidi, Bahareh Hassanzadeh, Karna Sherwood, Wei Ma, Michael Rosenberg, Varda Gilad, Gad Gilad

P7.095

Assessment of 2 Patients with Myotonia Congenita Following Intravenous Lidocaine Treatment  Saugat Dey, David Roshal, Luisa Rojas, Robert Schwartzman, Anahita Deboo, Terry Heiman-Patterson

P7.096

Angiotensin Receptor Blockade Can Ameliorate Peripheral Nerve Inflammation in Experimental Autoimmune Neuritis  Toshiki Fujioka, Hisao Kitazono, Wataru Hagiwara, Masashi Inoue, Shingo Konno

P7.097

Agomelatine Increases Muscle Strength and Reduces the Expression of Inflammatory Cytokines in mdx Dystrophic Mice  Alzira Carvalho, Vinicius Tondato, Larissa Iamnhuk, Fernanda Gomiero, Giuliana Petri, Pamela Delgado, Beatriz Alves, Fernando Fonseca, David Feder

3:00 p.m.–6:30 p.m. P7.098

Assessment of Bulbar Function in ALS Clinical Trials Richard Smith, Gary Pattee, Erik Pioro, David Schoenfeld

Neuromuscular Health Services/ Outcomes Research P7.099

Ig Treatment Outcomes Assessment and Clinical Guidelines Study (the “INSIGHTS Study”): Preliminary Findings on Scope of Practice from the INSIGHTS Database  Todd Levine, Jonathan Katz, Richard Barohn, Tahseen Mozaffar, Gil Wolfe, David Saperstein, Lara Katzin, Mazen Dimachkie, Elissa Ritt, Leslie Vaughan, Michelle Greer

P7.100

Trends in Outcome and Cost of Hospitalization of Elderly Myasthenia Gravis Patients from 1992 to 2009 Data from Nationwide Inpatient Survey (NIS)1997-2009  Andrew Ji, Ankit Pahwa, Nizar Souayah

P7.101

Racial and Ethnic Differences Across Amyotrophic Lateral Sclerosis (ALS) Cases from Three State and Eight Metropolitan Area Surveillance Projects  Lindsay Rechtman, Heather Jordan, Laurie Wagner, D. Kevin Horton, Wendy Kaye

P7.102

Profile of Medical Care Costs in Patients with Amyotrophic Lateral Sclerosis in Medicare Program and Under Commercial Insurance  Lisa Meng, Scott Jordan, Amy Bian, Jinsy Andrews, Jeremy Shefner, Andrew Wolff, Helen Blumen, Kosuke Iwasaki, Bruce Pyenson

P7.103

Is Intravenous Immunoglobulin More Cost Effective Than Plasmapheresis in Treatment of Pediatric Myasthenia Gravis Patients? Data from Kids’ Inpatient Database (KID) and Nationwide Inpatient Sample (NIS)  Ankit Pahwa, Rania Elenein, Nizar Souayah

P7.104

The Safety Profile of Home Infusion of Intravenous Immunoglobulin in Neuroimmunological Disorders Ankit Pahwa, Melissa Allan, Shari O’Connor, Kelly Corl, Nizar Souayah

P7.105

Trends in Outcome and Cost of Hospitalization of Adult Myasthenia Gravis. Data Analysis from Nationwide Inpatient Survey (NIS) from 1992 to 2009 Wenzhuan He, Weizhen Wang, Anshul Saxena, Hafiz Khan, Ankit Pahwa, Nizar Souayah

P7.106

ALD Connect, an Allinclusive Consortium to Improve Care and Drug Discovery for X-Linked Adrenoleukodystrophy  Florian Eichler, Ben Lenail, Keith van Haren, Ali Fatemi, Anthony Gonzalez, Gerald Raymond, Leila Jamal, Joshua Bonkowsky, Sanjay Magavi, John Fink, Tara O’Meara, Robert Brown, Amber Salzman, Alexander Sherman

P7.107

Con-focal Microscopy Documents Significant Epidermal Nerve Demyelization in Patients with Clinical Neuropathy But Normal Neurophysiologic Studies  Amiram Katz

2O14 Scientific Abstract Listing and Annual Meeting Information

P7.108

Validation of Diseasespecific Patient Reported Outcomes in the Home Environment  Gretchen Ayer, Lisa Christopher-Stine, Shafeeq Ladha, Tahseen Mozaffar, Yuen So, Michael Hehir, Nicholas Silvestri

Neuromuscular Outcome Measures P7.109

Axonal GBS in a Midwest Medical Center; Clinical Characteristics and Outcome  Muna Irfan, Pezhman Roohani, Ezgi Tiryaki

P7.110

Recommended Cut-off Values for Diagnosis of Carpal Tunnel Syndrome Using Ultrasonography in Females Ha Ra Jeon, Jung Bin Shin, Seong Woo Kim, Hyoung Seop Kim, Ji Sung Hong, Da Wa Jung, Da Sol Ha, Hyo In Kim, Jin Hyoung Lee

P7.111

Efficacy and Safety of Home Infusion of Intravenous Immunoglobulin in Multifocal Motor Neuropathy: A Longitudinal Study.  Gretchen Ayer, Nizar Souayah

P7.112

Efficacy and Safety of Video Assisted Thoracoscopic Surgery Thymectomy for Myasthenia Gravis With and Without Thymoma: A Comparative Study  Deepa Dash, V. Goyal, A. Kumar, G. Shukla, M. Behari

P7.113

A Retrospective Analysis of Patient-reported Outcomes for 34 Patients with Stiff Person Syndrome Receiving Home IVIG Infusions.  Shafeeq Ladha, Gretchen Ayer, Nizar Souayah

P7.114

Electrophysiological Motor Unit Function in SMNΔ7 Mice Following SMN Restoration  William Arnold, Vicki McGovern, Xiaohui Li, Arthur Burghes

P7.115

Neuropathy Signs and Tests in Therapeutic Trials of Transthyretin Amyloidosis Polyneuropathy Narupat Suanprasert

P7.116

Retrospective Review of Patients with Sciatic Nerve Palsy After Total Joint Arthoplasty  Teena Shetty, Erin Manning, Kelianne Cummings, Christine Villegas, Niesha Voigt, Maxwell Singer, Joseph Nguyen

P7.117

Perceived Fatigue and Physiological Fatigue in Spinal Muscular Atrophy (SMA): Are They Related? Sally Dunaway, Jacqueline Montes, Samantha Kramer, Bernadette Podwika, Ashwini Rao, Darryl De Vivo

Cerebrovascular Disease and Interventional Neurology: Issues in Acute Stroke Treatment P7.118

The Discharge Modified Rankin Scale Score Correlates with Established Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated with Thrombolysis  David Asuzu, Karin Nystrom, Janet Halliday, Charles Wira, David Greer, David Pritchard, Joseph Schindler, Kevin Sheth

Poster Session VII

P7.119

Predictors of Hemorrhagic Transformation of Acute Ischemic Stroke: Prospective Validation of a Hemorrhage Risk Model  Elisabeth Marsh, Rafael Llinas, Argye Hillis, Rebecca Gottesman

P7.120

The Western States Stroke Consortium Telestroke Project  Gene Sung, Bart Demaerschalk, Christopher Fanale, Jennifer Majersik, Matthew Grantz, Nobl Barazangi, Dan Capampangan

P7.132

Perception of Stroke Symptoms and Utilization of Emergency Medical Systems in Argentina Maximiliano Hawkes, Ismael Calandri, Mauricio Farez, Julieta Arena, Virginia Pujol Lereis, Sebastian Ameriso

P7.133

Awareness of Stroke and Knowledge of its Warning Signs and Risk Factors in a Developing Country Omer Sokrab, Ahmed Sokrab, El Fadil Hassan

P7.121

“Tele” Phone Medicine—Is Hearing Enough?  Rebecca Sugg, Milner Jessica, Alexander Auchus

P7.134

P7.122

P7.135

Why Ischemic Stroke Patients Do Not Receive Thrombolytic Treatment?  Sourabh Lahoti, Jessica Lee

P7.123

Intravenous Thrombolysis Resulting in Acute Ischemic Stroke Recanalization Can Lead to Cerebral Hyperperfusion Syndrome  Jonathan Ong, Leonard Yeo, Eric Ting, Arvind Sinha, Hock Luen Teoh, Bernard Chan, Chee Seong Seet, Vijay Sharma

P7.124

Cerebral Ischemic Events Associated with Intravenous Thrombolytic Administration in International Joint Efficacy Comparison of Thrombolytics (INJECT) Trial  Nudrat Tasneem, Malik Adil, Muhammad Suri, Adnan Qureshi

P7.125

A Smartphone Application to Aid in the Evaluation, Treatment, and Clinical Trial Enrollment of the Acute Stroke Patient  Claude Nguyen, Tzu-Ching Wu, Andrew Barreto, James Grotta, Sean Savitz

Cerebrovascular Disease and Interventional Neurology: Barriers and Opportunities in Acute Stroke Treatment

Stroke Awareness in Aseer Region, Community Based Cross Sectional Study  Adel Alhazzani Stroke Awareness Among Community Residents in Chicago Subin Mathew, Kathleen O’Neill, Heather Beckstrom, Fredrick Giles, Neelum Aggarwal, Shyam Prabhakaran

Cerebrovascular Disease and Interventional Neurology: Intracerebral Hemorrhage Outcome and Mortality P7.136

Hyperacute Neurologic Changes and Outcome after Intracerebral Hemorrhage  Matthew Maas, Michael Berman, James Guth, Eric Liotta, Shyam Prabhakaran, Andrew Naidech

P7.137

Body Mass Index and Intracerebral Hemorrhage Stephanie Holmes, Rajeev Garg, James Conners, Vivien Lee

P7.138

Predictors of Inpatient Mortality After Intracerebral Hemorrhage. Analysis of US Nationwide Inpatient Sample Database.  Vijayakumar Javalkar, Robert Schwendimann, Anil Nanda

P7.139

Where Are Opportunities to Increase Intravenous Thrombolysis in Current Practice?  George Koch, Nancy Kung, Dushyant Damania, Minal Jain, Anunaya Jain, Curtis Benesch, Babak Jahromi

Being Overweight or Obese Is Associated with Lesser Disability After Intracerebral Hemorrhage Neha Dangayach, Gian Marco De Marchis, Harpreet Grewal, Rachel Bruce, Aarti Chhatlani, Christina Falo, E. Sander Connolly, Sachin Agarwal, Jan Claassen, Michael Schmidt, Stephan Mayer

P7.127

P7.140

P7.126

Intravenous Thrombolysis Onset to Treatment Time Has a Small Effect on In-hospital Outcomes in Acute Ischemic Stroke  Konark Malhotra, Santosh Ramanathan, Chris Hackett, Matt Quigley, Melissa Tian, Jack Protetch, Crystal Wong, David Wright, Ashis Tayal

P7.128

Modified Helsinki Model Reduced Stroke Thrombolysis Delays in a Resource Limited, Non-Metropolitan Australian Hospital (RLNMAH) Nirosen Vijiaratnam, Elizabeth Mackey, Hans Tu, Zelko Matkovic, Tissa Wijeratne

Risk Factors and Outcomes of Prolonged Hospitalization After Intracerebral Hemorrhage in United States  Yogesh Moradiya, Santosh Murthy, Shreyansh Shah, Sneha Modi

P7.141

Antiplatelet Drugs Resumption After Antiplatelet-Related Intracerebral Hemorrhage In Chinese  Kay Cheong Teo, Gary Lau, Raymand Lee, Richard SK Chang, David CW Siu, Gilberto KK Leung, Raymond Cheung, Shu Leong Ho, Koon Ho Chan

P7.142

An Initiative to Improve Door to Needle Time for Stroke Thrombolysis in Chicago  Shyam Prabhakaran, Kathleen O’Neill

Warfarin Associated Intracerebral Hemorrhage in Hong Kong Chinese  Kay Cheong Teo, Neeraj R Mahboobani, Raymand Lee, David CW Siu, Raymond Cheung, Shu Leong Ho, Gary KK Lau, Koon Ho Chan

P7.130

P7.143

P7.129

Quality Improvement Project: Improving the Time To Treatment in Inpatient Acute Ischemic Stroke John Liang, Rocio Garcia Santibanez, Amy Walker, Irene Boniece

P7.131

The Presence of Neurology Impacting Door to Needle Time in Acute Stroke  Donna Kurowski, Oscar Soto

Blood Transfusion Does Not Improve Outcomes in Patients with Spontaneous Intracerebral Hemorrhage  Wazim Mohamed, Sanath Reddy, Sanjeev Sivakumar, Gregory Norris, Mohammad Ibrahim



P7.144

Seasonal Variation in the Incidence and Mortality of Intracerebral Hemorrhage.  Anand Patel, Archana Hinduja, Jamil Dibu, Eugene Achi, Rajan Patel

P7.145

Intracerebral Hematoma Volume Measurement Using ITK-SNAP Software: Initial Experience Monika Mishra, Priyank Shukla, Aakash Bodhit, Ganesh Asaithambi, Arnaldo Velez, Christian Rosado, Mohit Mishra, Pradeepan Saravanapavan, S Khan, V Reddy, Vishunmurthy Hedna

Cerebrovascular Disease and Interventional Neurology: Predictors of Outcome After Ischemic Stroke P7.146

Natural Autoantibodies in the Serum of Post-stroke patients with Different Clinical Outcomes  Alla Guekht, Eugene Gusev, Vera Alferova, Natalia Gulyaeva, Alexander Poletaev, Alexander Yakovlev

P7.147

Impact of Stroke Location on Stroke Outcome  Archana Hinduja, Kaustubh Limaye, Anand Patel, Zabeend Mahuwala

P7.148 WITHDRWN P7.149

Predictors of Outcome in Patients with Acute M2 Occlusion Muhib Khan, Jiaying Zhang, Majaz Moonis, Richard Goddeau, Nils Henninger

P7.150

Elderly Non-Demented Patients Have Better Outcome with Reperfusion Therapy Than Demented Patients Following Ischemic Stroke Neeta Duggal, Trenton Myers, James Kim, Iftekhar Ahmed

P7.151

Diastolic Function of Heart and Outcomes After Ischemic Stroke Ahn Hee Seung, Ryu Wi-Sun

P7.152

Combined Elevation of FVIII and von Willebrand Factor Predicts Risk for Worse Outcomes in Patients with Acute Ischemic Stroke (AIS)  Alyana Samai, Dominique Monlezun, Jr, Alexander George, Lauren Dowell, Laurie Schluter, Ramy El Khoury, Sheryl Martin-Schild

P7.153

Leukoaraiosis Is Associated with Impaired Functional Recovery and Outcome After Mild Ischemic Stroke.  Sanjeeva Onteddu, Artin Minaeian, Richard Goddeau, Nils Henninger

P7.154

Does the Magnitude of the Electrocardiogram QT Interval Dispersion Predict Stroke Outcome? Yitzchok Lederman, Leah Steinberg, Clotilde Balucani, Charles Philip, Jason Lazar, Jeremy Weedon, Gautam Mirchandani, Giovanna Viticchi, Lorenzo Falsetti, Mauro Silvestrini, James Gugger, David Aharonoff, Pirouz Piran, Zachary Adler, Steven Levine

P7.155

Areas of Cerebral Ischemia Have Increased Propensity to Convert to Infarct Among Diabetics  Wazim Mohamed, Sanath Reddy, Pratik Bhattacharya

Cerebrovascular Disease and Interventional Neurology: Post-Stroke Function P7.156

Return to Driving Following Stroke  Shelly Ozark, Andrea Boan, Tanya Turan, Charles Ellis, Daniel Lackland, David Bachman

P7.157

Evaluation of Sexual Functions of Women with Stroke  Haluk Gumus, Halim Yilmaz, Sema Yilmaz

P7.158

NIHSS Score May Help Predict Health Literacy Levels After Acute Ischemic Stroke  Kalina Sanders, Carmen Smotherman, Scott Silliman

P7.159

Dysphagia in Patients with Acute Ischemic Stroke  Mohamed AlKhaled, Christine Matthis, Georg Royl

P7.160

Relative Importance of Stroke Sequelae According to Patients and Caregivers.  Victor Urrutia, Brenda Johnson, Argye Hillis

P7.161

BMI Impact in Neurological Diseases  Jora Xhaxho, Sokrat Xhaxho, Drini Dobi, Jera Kruja

P7.162

The Association of Clinical Factors and Highly-Sensitive C-Reactive Protein (hsCRP) with Depression in Stroke Patients  Ahmed Itrat, Sandra Griffith, Nicolas Thompson, George Tesar, Irene Katzan

P7.163

Proteomics Reveals the Dysregulation of Lipid Metabolism in the Plasma of Post Stroke Depression Patients  Jun Mu

P7.164

Correlation of NIH Stroke Scale Change and Vascular Risk Factors in Acute Stroke Patients Prashanth Krishnamohan, Michael Dobbs

Cerebrovascular Disease and Interventional Neurology: Carotid Disease P7.165

Rates and Predictors of Five Year Survival in Asymptomatic Medicare Beneficiaries Undergoing Carotid Revascularization  Muhammad Suri, Saqib Chaudhry, Adnan Qureshi

P7.166

Influence of CREST on CEA and CAS Trends in Women—do the Results Matter?  Shahram Khalid, Sanath Reddy, Seemant Chaturvedi, Kumar Rajamani, Pratik Bhattacharya, Navid SerajiBozorgzad

P7.167

Carotid Artery Stent Placement and Carotid Endarterectomy in Patients with Dialysis Dependent Renal Failure  Malik Adil, Fahad Saeed, Adnan Qureshi

P7.168

Basilar TIAs of Symptomatic Carotid Artery Stenosis  Felix Veloso

P7.169

Symptomatic Carotid NearOcclusion with String Sign Incurs a Very High Risk of Stroke  Elias Johansson, Per Wester

P7.170

Carotid Artery Stenosis and Randomized Controlled Trials—Should We Abandon the Gold Standard  Akshal Patel, Gary Gronseth, Michael Glantz

Fast, Easy Registration Online  ·  AAN.com/view/AM14 121

Thursday May 1



First Authors stand by Posters from 5:00 p.m.–6:30 p.m



Thursday, May 1 P7.171

Early and Long-term Outcome After Carotid Endarterectomy Is Determined Not by Coexisting Traditional High Risk But by Risk of Coronary Heart Disease Only  Sung Hyuk Heo, Hyojung Nam, Jinsan Lee, Dae-Il Chang, Seon Hee Bu

P7.172

Are Carotid Artery StenosisIsolated and Carotid Artery-Plus Two Distinct Entities?  Vishal Jani, Adil Malik, Syed Hussain, Adnan Qureshi

P7.173

Pituitary Apoplexy: An Unusual Complication of Carotid Endarterectomy  Sandrine Jeangette, Denis Bataille, Guy Bruninx, Christo Chaskis, Raphael Hourez

P7.174

Association of Resting Heart Rate with Cerebrovascular Risk Factors and Carotid Artery Stenosis.  Syed Hussain, Vishal Jani, Adnan Safdar, Anmar Razak, Mounzer Kassab, Malathi Rao, Asif Khan, Adil Malik, Adnan Qureshi

Headache: Treatment P7.175

Assessment of Cardiovascular Safety in Cynomolgus Monkeys Following IV Administration of LBR-101  Sarah Walter, Michele Bronson, Marcelo Bigal

P7.176

Spinning Out of Control: The Black Box of Basilar and Hemiplegic Migraine  Regina Krel, Paul Mathew, Warren Spinner, Shivang Joshi

P7.184

Incidence of Adverse Events with MAP0004 Does Not Increase with Increased Frequency of Dosing: Results from a Long-Term Phase 3 Study Paul Winner, Sylvia Lucas, Biao Lu, Emilee Connors, Frederick Freitag, Shashidhar Kori

P7.185

SUNCT Syndrome Responding to OnabotulinumtoxinA Injections: A Case Report  Jina Youn, Kerry Knievel

P7.186

The Durability of OnabotulinumtoxinA for the Treatment of Chronic Migraine: CLARITY Pilot Study  Andrew Blumenfeld, Andrew Inocelda, Cedric Cunanan, Chris Purdy, Laura Dalfonso, Raf Magar

P7.187

Headache and Treatment of Unruptured Intracranial Aneurysms Julieta Arena, Maximiliano Hawkes, Mauricio Farez, Lucia Pertierra, Alejandro Kohler, Dario Benito, Maria Goicochea, Virginia Pujol Lereis, Juan Miranda, Sebastian Ameriso

P7.188

Incobotulinumtoxin A for the Preventive Treatment of Chronic Migraine Headaches  Patrick Grogan, Andrew Robinson, Wendy Chao, Aven Ford

P7.189

The IV Pharmaokinetics of Single and Multiple Doses of LBR-101 in Healthy Volunteers  Sarah Walter, Rafael Escandon, Marcelo Bigal

P7.190

P7.177

Safety and Tolerability of LBR-101, a Humanized Monoclonal Antibody That Blocks the Binding of CGRP to Its Receptor—Results of the Phase 1 Program  Rafael Escandon, Michele Bronson, Sarah Walter, Marcelo Bigal

P7.178

P7.191

Randomized Controlled Trial: Targeted Neck Cooling in the Treatment of the Migraine Patient  Alexandra Gabriel, Jon Brown, Melvin Yee Successful Treatment of Spontaneous Low-Pressure Headache Due to Prominent Cervical CSF Leak with Cervical Epidural Blood Patch Eugene Wang, Dajie Wang

P7.179

Intranasal Capsaicin (IC) Rapidly Relieves the Pain of Migraine and Other Severe Headaches  Maria Alexianu, Anjan Chatterjee

P7.180

An Inpatient Course of Intravenous Dihydroergotamine Use for New Daily Persistent Headache Michael Eller, Amy Gelfand, Nina Riggins, Peter Goadsby

P7.181

Cerebral Blood Flow Velocity in Migraine and Tension-type Headache Patients  Sebnem Karacay Ozkalayci, Ceyla Irkec, Bijen Nazliel

P7.182

A Randomized, Open-label, Parallel Two-arm Study Evaluating the Efficacy of H.P. Acthar Injection Gel in the Treatment of Adults with Intractable Chronic Migraine  Laszlo Mechtler, John Rothrock, Roger Cady, Peter McAllister

P7.183

Trigeminal Trophic Syndrome with Intractable Pain, Successfully Treated with Spinal Cord Stimulation  Erin Golden, Carrie Robertson, John Moossy, Paola Sandroni, Ivan Garza

122

High Asymmetric Dimethylarginine Levels in Migraine During the Interictal Period  Aylin Reyhani, Yahya Celik, Talip Asil, Hakan Karadag, Ozgur Gunduz, Necdet Sut

P7.192

Effects of Antiepileptic Drugs on Spreading Depression in the Chick Retina: Implications for Migraine Prophylaxis  Joao De Moraes

P7.193

Lamotrigine as a Prophylactic Treatment for Migraine-Associated Vertigo: A Case Series  Lixin Zhang, Merika Wilson, Lisa Yamagishi

3:00 p.m.–6:30 p.m. P7.198

Cardiovascular and Hemodynamic Parameters in Women Following IV Administration of LBR101, a Monoclonal Antibody Against CGRP  Marcelo Bigal, Abbas Alibhoy, Michele Bronson, Sarah Walter, Rafael Escandon

P7.199

Efficacy and Safety of High Dose of Intravenous Methylprednisolone in Cluster Headache Patients Not Responders to Oral Therapy  Elisa Rubino, Paola De Martino, Giovanna Vaula, Salvatore Gentile, Lorenzo Pinessi, Innocenzo Rainero

P7.200

Safety of Dihydroergotamine Use in Patients with Symptoms of Hemiplegic or Basilar Type Migraine Brad Klein, Wael Hanna, Bhuvin Buddhdev, Mary Naglak

P7.201

Long Term Therapeutic Response of Sphenopalatine Ganglion (SPG) Stimulation for Cluster Headache— Pathway CH-1 Study  Miguel Lainez, Rigmor Jensen, Arne May, Charly Gaul, Anthony Caparso, Amy Goodman, Jean Schoenen

P7.202

Peripheral Nerve Blocks for Pregnant Patients with Headache Shravya Govindappagari, Tracy Grossman, Ashlesha Dayal, Brian Grosberg, Sarah Vollbracht, Matthew Robbins

P7.203

Efficacy and Safety of AVP-825, a Novel Breath-Powered™ Powder Sumatriptan Intranasal Treatment, for Acute Migraine  Roger Cady, John Messina, Jennifer Carothers, Ramy Mahmoud

P7.204

Initial Management of Migraine Headaches with Oral Medications in a Pediatric Emergency Unit Bhooma Aravamuthan, Kristine Williams, Soe Mar

MS and CNS Inflammatory Diseases: Treatment P7.205

An Observational Comparison of Natalizumab and Fingolimod Using JCV Serology to Randomize Therapy Robert Carruthers, Dalia Rotstein, Brian Healy, Tanuja Chitnis, Howard Weiner, Guy Buckle

P7.206

Cardiac Side Effects of Dihydroergotamine  Erin Bange, Robert Rennie, Betts Patti-Ann, Christina Szperka

Fingolimod Is Not Able to Inhibit Multiple Sclerosis Disease Reactivation After Natalizumab Discontinuation  Marco Capobianco, Alessia Di Sapio, Simona Malucchi, Maria Malentacchi, Manuela Matta, Francesca Sperli, Alessandra Oggero, Antonio Bertolotto

P7.196

Gammacore Device for Treatment of Migraine Attack: Preliminary Data  Licia Grazzi, Susanna Usai, Gennaro Bussone

P7.207

P7.197

P7.208

P7.194

A Critical Evaluation of Migraine Trigger Site Deactivation Surgery  Paul Mathew

P7.195

Transient Exacerbation Of Headache In Patients Receiving Intravenous Dihydroergotamine For Inpatient Management Of Chronic Migraine Does Not Alter Outcomes  Michael Eller, Amy Gelfand, Nina Riggins, Christoph Schankin, Peter Goadsby

Stopping Disease Modifying Therapy in Progressive Multiple Sclerosis—a Prospective Study Gary Birnbaum Comparison of Switching to Natalizumab Versus Remaining on Interferon-Beta or Glatiramer Acetate After On-Treatment MS Relapse Using Propensity-Matched Registry Data  Timothy Spelman, Tomas Kalincik, Fabio Pellegrini, Annie Zhang, Maria Trojano, Heinz Wiendl, Ludwig Kappos, Robert Hyde, Shibeshih Belachew, Freek Verheul, Francois Grand-Maison, Helmut Butzkueven

2O14 Scientific Abstract Listing and Annual Meeting Information

P7.209

Natalizumab in Multiple Sclerosis with Spinal Involvement Chiara Zecca, Christian Kamm, Gianna Carla Riccitelli, Mirjam Heldner, Matteo Caporro, Claudio Staedler, Claudio Gobbi

P7.210

Impact of Natalizumab Treatment for Multiple Sclerosis on Patientreported Physical Functioning Over 3 Years in US Clinical Practices  Timothy Vollmer, John Foley, Kavita Nair, Judith Stephenson, Timothy Niecko, Sonalee Agarwal, Crystal Watson

P7.211

Relapse Rates Among Patients with Multiple Sclerosis Who Switch from Interferon Therapy to Fingolimod or Glatiramer Acetate: A Retrospective US Claims Database Analysis  Raquel Lahoz, Niklas Bergvall, Neetu Agashivala, Ashish Pradhan, Gorana Capkun, Jonathan Korn, Allison Petrilla, Swapna Karkare, Catherine Balderston McGuiness, Charles Makin

P7.212

Reactivation During Switch from Natalizumab to Fingolimod: Is it Predictible?  Adil Maarouf, Anne Laure Pernelet, Adrien Maitrot, Nathalie Caucheteux, Laure Daelman, Marie-Pierre Chaunu, Laurent Pierot, Ayman Tourbah

P7.213

Multiple Sclerosis Symptom Recrudescence Is Common at the End of the Natalizumab Dosing Cycle John Ratchford, Regina Brock-Simmons, Amanda Augsburger, Sonya Steele, Kristie Mohn, Mandi Rhone, Jinyan Bo, Kathleen Costello

P7.214

Estimating the Onset of Efficacy with Teriflunomide in Patients with Relapsing Forms of Multiple Sclerosis  Jerry Wolinsky, Deborah Dukovic, Philippe Truffinet, Ludwig Kappos

P7.215

A Five-year Clinical Follow-up Study of Patients with Multiple Sclerosis Who Started Natalizumab  Luca Prosperini, Valeria Barletta, Laura De Giglio, Fulvia Fanelli, Giovanna Borriello, Carlo Pozzilli

P7.216

Natalizumab Therapy, How to Treat How to Stop: The TY-STOP Study  Marinella Clerico, Stefania De Mercanti, Federico Piazza, Eleonora Virgilio, Dario Gned, Vincenzo Brescia Morra, Roberta Lanzillo, Luca Amato, Mario Quarantelli, Angelo Ghezzi, Anna Bianchi, Damiano Baroncini, Giuseppe Salemi, Sabrina Realmuto, Maria Teresa Ferrò, Francesca Vitetta, Giulia Superti, Paola Cavalla, Mariangela D’Onghia, Damiano Paolicelli, Irene Schiavetti, Maria Pia Sormani, Lorenzo Pinessi, Maria Trojano, Luca Durelli

P7.217

Recommendations for Fingolimod Treated Patients Vacinated for Varicella Zoster Virus.  Sergio Stecchi, Cinzia Scandellari, Liliana Gabrielli, Tiziana Lazzarotto

P7.218

Treatment Satisfaction After Switching to Fingolimod Directly from an Injectable Therapy  Edward Fox, Keith Edwards, John Burch, Kevin McCague, Luigi Barbato

Poster Session VII

P7.219

Adherence to, and Effectiveness of, Treatment with Subcutaneous Interferon Beta-1a in Relapsing Multiple Sclerosis Patients Using RebiSmart™ for Self-Injection: Final Results of the One-Year International, Observational SMART Study Antonios Bayas, Jean-Christophe Ouallet, Boris Kallmann, Raymond Hupperts, Ulrich Fulda, Kurt Marhardt

P7.220

Improved Estimation of Treatment Effects: Analysis of Time to Recurrent Relapse with Fingolimod or Intramuscular Interferon Beta-1a Treatment Using the Proportional Means Model  Xiangyi Meng, M. Zahur Islam, Peter Chin, Nadia Tenenbaum, Gary Cutter

P7.221

Switching from Injectable Therapy Leads to High Continuation Rate on Fingolimod  Yves Lapierre, Daniel Selchen, Virginia Devonshire, Robyn Schecter

P7.222

Relapse Rates Among Patients with a History of Relapses Treated with Fingolimod Compared with Interferons or Glatiramer Acetate for the Treatment of Multiple Sclerosis: A Retrospective US Claims Database Analysis Jonathan Korn, Niklas Bergvall, Raquel Lahoz, Neetu Agashivala, Ashish Pradhan, Gorana Capkun, Allison Petrilla, Swapna Karkare, Catherine Balderston McGuiness, Charles Makin

P7.223

Efficacy of Fingolimod Therapy Does Not Depend on the Individual Body Mass Index in Patients with MS Thomas Dehmel, Clemens Warnke, Anne Mausberg, Kathleen Wolffram, Maria Diaz-Lorente, Hans Hartung, Bernd Kieseier

P7.229

Marburg Variant Multiple Sclerosis, Responsive to Natalizumab Acutely and Chronically  Sara Mayer, Adam Carpenter, Pezhman Roohani

P7.230

Fingolimod Treatment In Relapsing-Remitting Multiple Sclerosis Patients: A Clinical Practice Experience  Rocco Totaro, Gianfranco Costantino, Roberta Fantozzi, Paolo Bellantonio, Caterina Di Carmine, Aurora Fuiani, Ciro Mundi, Stefano Ruggieri, Antonio Carolei

P7.231

Prospective Evaluation of Persistence, Treatment Adherence, Quality of Life, and Treatment Satisfaction in Patients Treated with an Intramuscular Interferon Beta-1a Autoinjector in a RealWorld Clinical Setting  Antonio Salgado, Veit Becker, Raymond Hupperts, Claes Martin, Sergio Slawka, Xiaojun You, Bjorn Sperling

P7.232

Comparison of Efficacy and Treatment Satisfaction of Patients on Baseline Therapy or Fingolimod: Results of the Interim Analysis of Two German Registry Studies PANGAEA and PEARL  Tjalf Ziemssen, Sylia Moser, Alexandra Fuchs, Christian Cornelissen

P7.233

Fingolimod First-dose Effects in Patients with Relapsing-Remitting Multiple Sclerosis Concomitantly Treated with Serotonin-Specific Reuptake Inhibitors  Robert Bermel, Ron Hashmonay, Xiangyi Meng, Philipp Von Rosenstiel, Nicolaos Sfikas, Simrat Randhawa, Daniel Kantor

P7.234

Positive Response to Alemtuzumab (ALE) Rescue Immunotherapy in a High Disability, Treatment-Refractory Multiple Sclerosis (MS) Cohort Samuel Hunter, Heli Hunter, Daniel Kantor

Systematic Literature Review and Network Meta-Analysis of Pegylated Interferon Beta-1a and Disease Modifying Therapies for Relapsing/Remitting Multiple Sclerosis  Keith Tolley, Michael Hutchinson, Andrew Pachner, Elizabeth Kinter, Bjorn Sperling, Xiaojun You, Ping Wang, Ankush Taneja, Mohd. Kashif Siddiqui

P7.225

P7.235

P7.224

Persistence and Adherence of Fingolimod Compared with Other DiseaseModifying Therapies for the Treatment of Multiple Sclerosis: A Retrospective US Claims Database Analysis Jonathan Korn, Niklas Bergvall, Raquel Lahoz, Neetu Agashivala, Ashish Pradhan, Gorana Capkun, Allison Petrilla, Swapna Karkare, Catherine Balderston McGuiness, Charles Makin

P7.226

Clinical Predictors for Fingolimod (Gilenya) Treatment Response in Multiple Sclerosis Patients  Dalia Rotstein, Muhammad Taimur Malik, Brian Healy, Howard Weiner, Tanuja Chitnis

P7.227

Changes in Natalizumab Treatment Patterns and Association with Relapse Outcomes: A Retrospective Study  Robert McQueen, Brieana Buckley, Terrie Livingstone, Timothy Vollmer, John Corboy, Kavita Nair, Jonathan Campbell

P7.228

A Two-Year Retrospective Analysis of Rituximab Therapy in Secondary-Progressive Multiple Sclerosis  Christopher Perrone, Biljana Beretich, Peter Riskind, Carolina Ionete

Treatment Satisfaction, Adherence and Behavioral Assessment in Patients De-Escalating from Natalizumab to Interferon Beta  Claudio Gobbi, Gianna Riccitelli, Pasquale Calabrese, Emanuele Pravatà, Ursula Candrian, Charles Guttmann, Chiara Zecca

P7.236

The Providence MS Center’s Dimethyl Fumarate (DMF) Registry Kyle Smoot, Bobbie Lee Roth, Chiayi Chen, Kiren Kresa-Reahl, Leah Gaedeke, Stanley Cohan

P7.237

Pharmacokinetics of Laquinimod, an Oral Immunomodulatory Agent in Development for The Treatment of Relapsing-Remitting Multiple Sclerosis  Hayrettin Tumani, Tjalf Ziemssen, Friedemann Paul, Martin Marziniak, Nils Richter, Christoph Heesen, Yossi GilgunSherki, Tali Gorfine, Ofer Spiegelstein, Emil Samara, Yulia Sidi, Dorit Mimrod

P7.238

Clinical And Radiological Activity During The Fingolimod Treatment Prescribed After Natalizumab. A Multiple Sclerosis Unit Experience  Rocio Hernandez Clares, Ester Carreon, Begoña Palazon, Encarnación Andreu, Jose Javier Martin, Jose Meca La Llana



P7.239

Safety and Efficacy in Patients Receiving Natalizumab Therapy in Hungary  Tunde Csepany, Lovas Gabor, Bencsik Krisztina, Csilla Rozsa, Magdolna Simo, Krisztina Kovacs, Samuel Komoly, Peter Barsi, Zoltan Mor

P7.240

Subcutaneous Interferon Beta1a Decreases the Evolution of GadoliniumEnhancing Lesions Into Chronic Black Holes in Relapsing Multiple Sclerosis Anthony Traboulsee, David Li, Yinshan Zhao, Roger Tam, Guojun Zhao, Yan Cheng, Andrew Riddehough, Fernando Dangond, Juanzhi Fang, Ludwig Kappos

P7.241

Risk Factors for Relapses After Switching from Natalizumab to Fingolimod  Joachim Havla, Robert Hoepner, Christian Eienbröker, Bjorn Tackenberg, Kerstin Hellwig, Ingrid Meinl, Ralf Gold, Reinhard Hohlfeld, Tania Kuempfel, Ingo Kleiter

P7.242

Short-term Follow-up of Central Motor Conduction Failure in Relapsing Multiple Sclerosis Patients Undergoing High-dose Steroid Treatment  Alessia Di Sapio, Antonio Bertolotto, Federica Melillo, Simona Malucchi, Paola Berchialla, Francesca Sperli, Walter Troni

P7.243

Epidemiological Study to Identify Factors That Influence Clinical Decision Making in Patients with Relapsing Remitting Multiple Sclerosis (RRMS) After at Least 2 Years of Treatment with Immunomodulators in Germany (EPIDEM)  Stephan Schmidt, Petra Schicklmaier, Christine Winterstein, Wettmarshausen Christine, Matthias Meergans, Colin Wernsdoerfer

Treatment of Specific Multiple Sclerosis Symptoms P7.244

Dalfampridine Real World Utilization and Efficacy Assessment Sylvia Klineova, Joshua Friedman, Colleen Farrell, Christine Hannigan, Fred Lublin, Stephen Krieger

P7.245

Aspirin Is Unlikely to Have a Clinically Meaningful Effect on Multiple Sclerosis-Related Fatigue: Data from a Randomized Controlled Trial Dean Wingerchuk, Mark Keegan, Elizabeth Shuster, Jonathan Carter, Joe Hentz, Greg Thaera, Melissa Cortez, Moses Rodriguez

P7.246

Effects of Prolonged-Released Fampridine on Walking Parameters, Upper Limb Function, Fatigue and Quality of Life  Etienne Allart, Anne Benoit, Anne Blanchard, Helene Zephir, Olivier Outteryck, Arnaud Lacour, Patrick Vermersch

P7.247

Prolonged-release Fampridine (Fampyra®) Post-marketing Experience in the Alsace Region  Jean-Claude Ongagna, Carole Berthe, Nicolas Collongues, Frederic Blanc, Jerome De Seze

P7.248

Long-Term Course and Clinical Assessment Parameters of Patients with Multiple Sclerosis Under Dalfampridine  Tobias Ruck, Stefan Bittner, Nico Melzer, Heinz Wiendl, Matthias Schilling, Sven Meuth

P7.249

Monotherapy with THC/ CBD Spray in Multiple Sclerosis Induced Spasticity  Juergen Koehler, Walter Poellmann, Wolfgang Walter Feneberg, Martin Meier

P7.250

Use of Medical Marijuana for Symptoms of Multiple Sclerosis (MS) Among Participants of the Pacific Northwest MS Registry (PNWMSR)  Tamela Stuchiner, Elizabeth Baraban, Chiayi Chen, Stanley Cohan

P7.251

Attenuation of Dimethyl Fumarate-related Gastrointestinal Symptoms with Montelukast Carmelo Tornatore, Faria Amjad

P7.252

25G Sprotte Needle Strongly Reduces the Risk of Post-Lumbar Puncture Headache in Clinical Practice. Antonio Bertolotto, Francesca Sperli, Marco Capobianco, Maria Malentacchi, Annalisa Pulizzi, Simona Malucchi

P7.253

A Double-blind Placebo Controlled Study of the Effect of BetaAlanine, a Nonessential Amino-Acid, on Neurologic, Motor Function, Quality of Life, and Fatigue in Patients Diagnosed With Multiple Sclerosis  John Kanter, Elizabeth Keiner, Arielle Biwer, Elizabeth Coughlin, Brittany DiFabio, Donya Salmasinia, Michael Ormsbee, John Giannini, Charles Maitland

Neuro-oncology: CNS Metastases and Complications of Treatment P7.254

Brain Metastases In Ovarian Cancer—a Comprehensive Review.  Shabnam Pakneshan, Damoun Safarpour, Fattaneh Tavassoli, Bahman Jabbari

P7.255

A Case of Primary Meningeal Melanoma  Bhaskar Roy, Fatmah Al Zahmi, Richard Danialan, Srinivas Mandavilli

P7.256

Isolated Primary CNS Infiltrative Parenchymal Histiocytosis with Intraventricular Hemorrhage Eric Mittelmann, Patrick LaSala, Karen Weidenheim, Jerome Graber

P7.257

Brainstem Glioma 8 Years After External Beam Radiotherapy for Pituitary Macroadenoma: Correlation with Radiation Treatment Dose and Volume  Salim Abboud, Leo Wolansky, Sunil Manjila, Simon Lo, Bahaudden Arafah, Warren Selman, Lisa Rogers

P7.258

Effects of Ionizing Radiation on Human Microglial Cells  Hongxin Chen, Sonia De Toledo, Edward Azzam, Nizar Souayah

Neuro-oncology: Primary CNS Lymphoma and Other Hematologic Malignancies P7.259

Salvage Therapy with Bendamustine for Methotrexate Refractory Recurrent Primary CNS Lymphoma: A Retrospective Case Series Marc Chamberlain

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Thursday May 1



First Authors stand by Posters from 5:00 p.m.–6:30 p.m



Thursday, May 1 P7.260

Primary Natural Killer/T-cell Lymphoma Presenting as Leptomeningeal Disease  Carlos Kamiya-Matsuoka, Bing Liao, Yun Gong, Merry Chen, Karin Woodman, Nathan Fowler, Charles Conrad

P7.261

Rituximab and Bendamustine for CNS Involvement by Chronic Lymphocytic Leukemia  Geraldine Faivre, Samuel Singer, Lisa DeAngelis, Ariela Noy, Antonio Omuro

P7.262 Neurolymphomatosis:

Heterogenous Presentations Daniel Winkel

P7.263

VEGF and Pentraxin-3 Levels in POEMS Syndrome: A 2-Year Longitudinal Study.  Chiara Dalla Torre, Marina Scarlato, Federica Lessi, Marta Campagnolo, Marta Lucchetta, Susanna Ruggero, Elisabetta Toffanin, Angelo Manfredi, Mario Ermani, Fausto Adami, Chiara Briani

P7.264

Bing-Neel Syndrome: Presentation of Three Unusual Patients  Louis Royer-Perron, François Moreau, Sylvie Gosselin

P7.265

Central Neuropathy in a Patient with Waldenstrom’s Macroglobulinemia: Should You Suspect Bing-Neel Syndrome Even in the Absence of Abnormal Brain Imaging?  Neha Gupta

Neuro-oncology: Primary CNS Tumors: Gliomas P7.266

Hormone Replacement Therapy and Risk of Glioma: A Nationwide Nested Case-Control Study Lene Andersen, Soren Friis, Jesper Hallas, Pernille Ravn, David Gaist

P7.267

Epilepsy and Clinical Neurophysiology (EEG): Surgery and Neurostimulation

Aging, Dementia, and Cognitive and Behavioral Neurology: Attention/Neglect

P7.275

P7.286

Outcome of Intracranial EEG Monitoring and Surgery in MRI-negative Temporal Lobe Epilepsy  Ricky Lee, Marietta Hoogs, David Burkholder, Max Trenerry, Joseph Drazkowski, Jerry Shih, William Tatum, Gregory Cascino, Elaine Wirrell, Gregory Worrell, Elson So

P7.276

Comparison of Seizure Outcome After Selective Amygdalohippocampectomy in Adult Versus Pediatric Onset Temporal Lobe Seizures  Aradia Fu, Steve Chung

P7.277

Reasons for Delayed Temporal Lobe Epilepsy Surgery  Aditi Narechania, Paz Abergel, Irena Garic, Michael Macken, Elizabeth Gerard, Stephan Schuele

P7.278

Surgical Outcome of Parietal Lobe Epilepsy  Anna-Marieta Moise, Janice Jordan, Lola Morgan, Linda Leary, Kameel Karkar, Octavian Lie, Jose Cavazos, JeanLouis Caron, Alexander Papanastassiou, Charles Szabo

P7.279

Electrical Stimulation of the Anterior and Centromedian Nucleus of Thalamus for Treatment of Refractory Epilepsy—Report of Four Cases  Wei Hu, Bryan Klassen, Kendall Lee, Daniel Clayton, Squire Stead

P7.280

Deep Brain Stimulation for the Management of Seizures in MECP2 Duplication Syndrome.  Fabio Nascimento, Hanna Faghfoury, Timo Krings, Anfal Ali, Jonathan Fridhandler, Andres Lozano, Richard Wennberg, Danielle Andrade

Relationship Between CD44v6 and E-cadherin Expression in Human Primary Brain Tumors  Leslaw Zub, Boguslaw Paradowski, Julia Bar, Anna LisNawara, Leszek Noga, Michal Jelen

P7.281

P7.268

A Novel Therapeutic Target for Treatment of Malignant Brain Tumors  Nazanin Majd, Kazutaka Sumita, Hirofumi Yoshino, Dillon Chen, Atsuo Sasaki

P7.282

P7.269

P7.283

Posterior Fossa Recurrences of Supratentorial WHO Grade II and III Gliomas  Robert Terziev, Gregorio Petrirena, Jean-Yves Delattre

P7.270

Posterior Fossa Tumours in Children as Seen in a Tertiary and Referral Hospital in Sub-Saharan Africa Victor Kwasi

P7.271

Oligodendroglial Gliomatosis Cerebri Exhibiting Leptomeningeal and Nerve Root Involvement  Grace Mcmacken, Brian Herron, Ailsa Fulton

P7.272

A Case Report: Primary Glioblastoma of the Pineal  Regina Krel, Yana Krutoshinskaya, Arthur Rosiello, Roberta Seidman, Agnes Kowalska

P7.273

Aggressive Medical Care at the End of Life (EOL) in Glioblastoma (GBM): The 5-year Memorial Sloan-Kettering Cancer Center (MSKCC) Experience Alexis Dallara, Alan Carver, Eli Diamond

3:00 p.m.–6:30 p.m.

The Efficacy of VNS in Patients with Pharmacoresistant Epilepsy of Temporal Versus Extra-temporal Locations  Abuhuzeifa Abubakr, Ilse Wambacq Prospective Memory After Mesial Temporal Resection  Carla Adda, Luiz Henrique Castro, Carmen Jorge, Rosa Valerio, Hung Wen Database Systems and Online Tools for Early Referral to Epilepsy Surgery Evaluation in Mesial Temporal Lobe Epilepsy  Rodolfo Callejas, Ildefonso Rodriguez-Leyva

P7.284

Association Between Chronobiology of Seizures and Hemispheric Laterality in Patients Who Underwent Surgery for Refractory Epilepsy Anca Popescu, Amrit Misra, Maromi Nei

P7.285

Vagal Nerve Stimulation and Cortical Source Localization in Pre- and Post-operation EEG Data: A Case Study  Hakan Ekmekci, Mastaneh Torkamani Azar, Ali Okatan, Serefnur Ozturk

Memantine Effects on Attention in FXTAS: A Double-blind ERP Study  Jinchen Yang, Annette Rodriguez, Merve Avar, Ryan Brill, Christa Simon, Yu-Qiong Niu, Ashley Royston, Randi Hagerman, John Olichney

P7.287

The Mind’s Eye: Effects of Aging, Hemispace and Movement Direction on Estimates of Distance  Tigran Kesayan, Adam Falchook, John Williamson, Kenneth Heilman

Emergence of New Responders to Treatment and New Adverse Events in Clinical Trials of Pregabalin in Diabetic Peripheral Neuropathy and Postherpetic Neuralgia  Parsons, Birol Emir

P7.300

Contact Heat Evoked Potentials Stimulator (CHEPS) in the Assessement of Painful Leprosy Neuropathy  Camila Pupe, Osvaldo Nascimento, Marcos Freitas, Eduardo Davidovich, Caroline Bittar, Ricardo Dornas, Bruno Coutinho

P7.301 Pharmacological,

Predictors of Recovery of Allocentric and Egocentric Neglect: The Role of Education  Joseph Posner, Lydia Trupe, Cameron Davis, Yessenia Gomez, Donna Tippett, Argye Hillis

Pharmacokinetics and Safety Profiles of DS-5565, a Novel α2δ Ligand Tomihisa Yokoyama, Naohisa Arakawa, Yuki Domon, Fumihiko Matsuda, Tatsuya Inoue, Yutaka Kitano, Makoto Takahashi, Naotoshi Yamamura, Kiyonori Kai

P7.289

P7.302

P7.288

Spatial Neglect Commonly Occurs After Traumatic Brain Injury Peii Chen, Irene Ward, Kimberly Hreha, Yan Liu, Ummais Khan

P7.290

Changes of Vertical and Horizontal Pseudoneglect with Aging  Nicholas Milano, Anouchka Douyon, Adam Falchook, Kenneth Heilman

P7.291

Effects of Gaze, Head and Hand Location on Motor Function: Evidence from TMS in Normal Subjects  H. Coslett, Olu Faseyitan, Jared Medina, Michael Iannacone

P7.292

Things Look Up With Aging  Anouchka Douyon, Adam Falchook, Kenneth Heilman, Nicholas Milano

P7.293

Leftward Where Bias and Rightward Distraction in Chronic Neglect.  A. Barrett, Kelly Goedert, Mooyeon Oh-Park

P7.294

Spatial Neglect and Parkinson Disease  Adam Falchook, Liliana Salazar, Dan Neal, Tigran Kesayan, John Williamson, Irene Malaty, Nikolaus McFarland, Michael Okun, Ramon Rodriguez, Aparna WagleShukla, Kenneth Heilman

P7.295

Apparent Body Size Alters Motor Function  H. Coslett, Jared Medina, Olu Faseyitan

Pain and Palliative Care P7.296

Central Nervous System Safety and Tolerability of DS-5565: A Randomized, Double-Blind, Placebo- and Active Comparator-controlled Phase II Study in Diabetic Peripheral Neuropathic Pain  Aaron Vinik, Uma Sharma, Karen Feins, Ching Hsu, Domenico Merante

P7.297

Pharmacologic and Non-Pharmacologic Treatments of Adolescents with Chronic Tension-type Headache.  Peter Przekop, Allison Przekop

P7.298

Efficacy of Pregabalin in the Treatment of Prediabetic Neuropathic Pain  Maria Alejandra Gonzalez Duarte, Karla Cardenas-Soto, Monica Lem, Cinthia Castillo, Christopher Gibbons, Roy Freeman

P7.274

Neuro-oncology Telemedicine Follow-up Visits  Richard Green, Emily Woyshner, Amanda Hauser Dehaven

124

P7.299

2O14 Scientific Abstract Listing and Annual Meeting Information

An Assessment of Pain Reports in Amyotrophic Lateral Sclerosis Using Three Large Data Sets Helen Stephens, Stephanie Felgoise, Susan Walsh, Zachary Simmons

P7.303

Parkinson’s Disease Patients’ Preferences for Communication About Advanced Care Planning  Keiran Tuck, Lissa Brod, John Nutt, Erik Fromme

P7.304

Quality of Care in the Recognition and Management of Pain Syndromes at the Emergency Room of a Tertiary Hospital from January 2010-December 2010 (A Needs Assessment)  Ma. Alma Carandang, Amado San Luis

P7.305

Mindfulness-Based Therapies in the Treatment of Somatization Disorders: A Meta-Analysis  Lakhan Shaheen

P7.306

False Localizing Exam in a Lumbar Spinal Epidural Abscess (SEA): Right Paraspinal Pain and Contralateral Leg Weakness  Pavis Laengvejkal, Inhyup Kim, Kunut Kijsirichareanchai, Sahawat Tantikittichaikul, John DeToledo

P7.307

The PRIZM (Patient Registry of Intrathecal Ziconotide Management) Study for Patients with Severe Chronic Pain  Michael Saulino, David Caraway, Eric Grigsby, Michael Leong, Richard Rauck, Timothy Deer, Philip Kim, Mark Wallace, Gladstone MCDowell, Sonja Hokett, Sarah Alvarez-Horine, Geertrui Vanhove

P7.308

Relationship Between Pharmacokinetics and Urine Drug Screen for Opioids: A Method to Determine Efficacy, Safety and Abuse  Fadi Delly, Gulshan Oberoi, Rudram Muppuri, Shushovan Chakrabortty

P7.309

Persistent Na+ and K+ Channel Dysfunctions After Chronic Exposure to Insecticides and Pyridostigmine Bromide  Nan Jiang, Thomas Nutter, Brian Cooper

P7.310

Pain Profiles in Small Fiber Neuropathy  Maria Alejandra Gonzalez Duarte, Karla Cárdenas-Soto, Mónica Lem, Cinthia Castillo, Enoe Cruz-Martinez

Poster Session VII

P7.311

Contact Heat Evoked Potentials Stimulator (CHEPS) and Thermal Quantitative Sensory Testing (QST) in the Assement of Atypical Orofacial Pain Bruno Coutinho, Osvaldo Nascimento

P7.312

Shifts in Pain Severity Categories Among Patients with Painful Diabetic Peripheral Neuropathy or Postherpetic Neuralgia Treated with Pregabalin  Parsons Bruce, Birol Emir

P7.313

Pharmacokinetics of DS-5565, a Novel α2δ Ligand, in Rats and Monkeys, and Assessment of DDI Risk Naotoshi Yamamura, Makiko Yamada, Makoto Takahashi, Minoru Uchiyama, Hiroko Koda, Tsuyoshi Mikkaichi, Yumi Nishiya, Tomoyo Honda, Naohisa Arakawa, Yuki Domon, Thomas Fischer, Juergen Mueller

P7.314

Suicide in a Woman Diagnosed with Bulbar Predominant Amyotrophic Lateral Sclerosis: A Case Report and Literature Review Maggie McNulty, John-Michael Li, Madhu Soni

P7.315

Approaching the Mechanisms Underlying Analgesia Induced by High Voltage Electrical Stimulation of Lumbosacral Nerve Roots  Walter Troni, Federica Melillo, Alessia Di Sapio, Antonio Bertolotto

P7.316

The Palliative Care Needs of Patients Living with Life-Limiting Neurological Illness  Marvin Chum, Valerie Schulz, Christopher Watling, Teneille Gofton

P7.317

Combined Supraorbital (SONS) and Occipital Nerve Stimulation (ONS) for Intractable Post-Herpetic Neuralgia  Robert Bulger, Francis Conidi, Kenneth Reed

P7.318

The Need for Early Recognition of Complex Regional Pain Syndrome to Facilitate Early Effective Treatment  Jacquelyn Laplant, Robert Knobler

Child Neurology and Developmental Neurology VI P7.319

Abnormal Measures of White Matter Integrity in Newborns with Hypoxic Ischemic Encephalopathy (HIE) Paola Pergami, Tania Nanavati, Bob Hou, Panitan Yossuck, Ashley Smith, Jeffrey Carpenter, Mark Haut

P7.320

A Noninvasive Neurotechnology, HIRREM, Is Associated with Symptom Reduction and Improved Cardiovascular Autonomic Measures in Adolescents with POTS  Catherine Tegeler, John Fortunato, Jared Cook, Sung Lee, Meghan Franco, Charles Tegeler

P7.321

A Novel SUCLA2 Mutation Associated with a Complex Childhood Movements Disorder  Caterina Garone, Juliana Gurgel-Giannetti, Simone SannaCherchi, Sindu Krishna, Ali Naini, Catarina M Quinzii, Michio Hirano

P7.322

An Unusual Presentation of Neuropathy Secondary to Leprosy (Hansen’s disease)  Derrece Reid, Debra Byler, Kimberly Harbaugh, Jennifer Baccon

P7.323

Increased Coherence Between the Basal Ganglia and Motor Cortex in a Rat Model of Pediatric Asphyxial Cardiac Arrest.  Bhooma Aravamuthan, Michael Shoykhet

P7.324 Neuro-Developmental

Disorders in India—From Epidemiology to Public Policy  Donald Silberberg, Narendra Arora, Vinod Bhutani, Maureen Durkin, Shefalli Gulati, Mkc Nair, Jennifer PintoMartin

P7.325

Rituximab Therapy as a First-line Immunosuppressive Treatment in Children with Neuromyelitis Optica Spectrum Disorder: A Single-center Experience.  Giulia Longoni, Brenda Banwell, Massimo Filippi, E. Ann Yeh

P7.326 Periventricularlaminar

Heterotopia (PLH): Characterization in a Series of 18 Patients  Dina Amrom, Firas Fahoum, Francois Dubeau, Gary Clark, Eugen Boltshauser, Paolo Curatolo, Renzo Guerrini, Ruben Kuzniecky, Anne Tsai, Parul Jayakar, Mitsuhiro Kato, A Barkovich, Donatella Tampieri, Denis Melancon, Frederick Andermann, Eva Andermann, William Dobyns

P7.327

A Case Report of 4H Syndrome Probably Caused by a Heterozygous Abnormality of the POLR3A Gene with Preserved Intellectual Function  Kuwabara Midori, Yuki Hatanaka, Takamichi Kanbayashi, Hidehiko Okuma, Masahiro Sonoo, Hirotomo Saitsu, Naomichi Matsumoto

P7.328

Sideroflexin-4 Defects Cause a New Infantile Mitochondrial Disorder Affecting Hematopoietic and Central Nervous Systems.  Caterina Garone, Gordon J Hildick-Smith, Jeffrey D Cooney, Laura S Kremer, Tobias B Haack, Jonathan N Thon, Non Miyata, Daniel Lieber, Sarah Calvo, Orhan H. Akman, Yvette Y Yen, Nicholas C Huston, Diana S Branco, Dhvanit I Shah, Matthew L Freedman, Carla M Koehler, Joseph E Italiano, Andreas Merkenschlager, Skadi Beblo, Tim Strom, Thomas Meitinger, Peter Freisinger, Alice Donati, Holger Prokisch, Vamsi Mootha, Barry Paw, Salvatore DiMauro

P7.329

Intrinsic Excitability Defects in Specific Subtypes of Medial Prefrontal Cortex Pyramidal Neurons in a Mouse Model of Autism  Audrey Brumback, Vikaas Sohal

P7.330

A Comparison of Colocated and Traditional Outpatient Consultation for the Treatment of ADHD in Two Urban Medical Homes: Costs and Outcomes  David Urion

P7.331

Ehlers-Danlos Type IV Presenting with a Peroneal Neuropathy  Amitha Ananth, Yaping Yang, Seema Lalani, Lotze Timothy

P7.332

Patients with Electrical Status Epilepticus in Sleep and Normal Magnetic Resonance Imaging Have Smaller Thalamic Volume than Controls  Ivan Sanchez Fernandez, Alireza Akhondi-Asl, Jacquelyn Klehm, Simon Warfield, Jurriaan Peters, Tobias Loddenkemper

P7.333

Brainstem Disconnection Syndrome in a Patient with Fetal Alcohol Syndrome  Chandan Mehta, Rajkumar Agarwal, Ajay Kumar, Mohsin Maqbool

P7.334

Cerebrospinal Fluid Opening Pressure in a Pediatric Demyelinating Disease Cohort  Sona Narula, Grant Liu, Robert Avery, Brenda Banwell, Amy Waldman

P7.335

Soto-like Syndrome and Cortical Malformation Associated with Chromosome 19p13.2 Microdeletion Including Nuclear Factor-1X (NFIX) Swati Karmarkar, Ina Amarillo, Douglas Larsen

P7.337

Neurocognitive and Psychological Profiles of Children with Idiopathic Epilepsy  Adel Eladl, Hoda Atwa

P7.338 Multi-domain

Neurodevelopmental Delays in Multiple Gestation and Singleton Preterm Infants  Imad Jarjour, Laila Jarjour, Alexandra Sibley

P7.339

Retrospective Review of Inpatient Headache Admissions: Looking AT Determinants of a Successful Admission  Arnold Sansevere

P7.340

Resting State EEG Serves as a Promising Biomarker of Cognitive and Language Function in Young Children with ASD.  Kevin McEvoy, Shafali Jeste

P7.341

Pathology of the Neurovascular Unit in Cerebral X-linked Adrenoleukodystrophy  Sandra Jimenez, Patricia Musolino, Tracey Suter, Florian Eichler

P7.342

Cortical Involvement in Early and Late Stages of Metachromatic Leukodystrophy  Jan-Mendelt Tillema, Marloes Derks, Petra Pouwels, Pim de Graaf, Frederik Barkhof, Marjo Van Der Knaap, Nicole Wolf

P7.343

Stroke due to Extracranial Internal Carotid Artery Dissection After Roller Coaster Rides in a 4-year-old Boy  Amre Nouh, Daniel Vela-Duarte, Thomas Grobelny, George Hoganson, David Pasquale, Jose Biller

P7.344

Video EEG Monitoring in Infants: Predictors of Subclinical Seizures in the ICU Setting  Eileen Broomall, Anna Mrelashvili, Elaine Wirrell

Movement Disorders: Other Parkinsonian Disorders P7.345

Case Study with Video Clips: Midbrain Dysfunction and Restoration in a 30-year-old Woman with Hydrocephalus  Sarah Dolgonos, Emmanuelle Schindler, Joshua Lovinger, Duarte Machado

P7.336

Efficacy of EPA Enriched Phosphatidylserine-Omega-3 (Vayarin) on Children with ADHD  Stephanie Nguyen, Cindy Nguyen, Robert Chudnow, Van Miller, Anthony Riela, Gerald So, Patricia Mireles, Lina Shah

Obtaining Your CME and Evaluations To receive CME for education programs or scientific sessions, evaluations must be completed online or via the Annual Meeting mobile app. Wireless internet hotspots will be available at the convention center. Details will be provided prior to the meeting.

Fast, Easy Registration Online  ·  AAN.com/view/AM14 125

Thursday May 1



First Authors stand by Posters from 5:00 p.m.–6:30 p.m



Thursday, May 1 S54 MS and CNS Inflammatory Disease: Neuroimaging II

S55 Pediatric Stroke and Stroke in the Young

3:15 p.m. S54.001 The Origin of Chronic T2* and Phase Rims in MS Lesions: A Longitudinal 7T MRI Study   Martina Absinta, Pascal Sati, Massimo Filippi, Daniel Reich

3:15 p.m. S55.001 Moyamoya Disease in Children: Results of the International Pediatric Stroke Study   Sarah Lee, Michael Rivkin, Adam Kirton, Gabrielle DeVeber, Jorina Elbers

3:30 p.m. S54.002 Is Primary Progressive Multiple Sclerosis a Disease Entity of its Own? Preliminary Results of a 7T MRI Study   Joseph Kuchling, Ivan Bozin, Jan-Markus Dörr, Lutz Harms, Berit Rosche, Thoralf Niendorf, Friedemann Paul, Tim Sinnecker, Jens Wuerfel

3:30 p.m. S55.002 Intraoperative Neurophysiologic Monitoring of Surgical and Endovascular Treatment of Pediatric Arteriovenous Malformations   Viet Nguyen, Santiago Avila, Leslie Lee, Sungho Cho, Scheherazade Le, Jaime Lopez

3:45 p.m. S54.003 Early Neuronal Damage in the Cervical Cord of Patients with Primary Progressive Multiple Sclerosis Demonstrated by MR Spectroscopy and Q-space Imaging   Khaled Abdel-Aziz, Torben Schneider, Bhavana Solanky, Claudia Wheeler-Kingshott, Day Brian, Marios Yiannakas, Daniel Altmann, Amy Peters, Alan Thompson, Olga Ciccarelli 4:00 p.m. S54.004 Relationships Between Quantitative Spinal Cord MRI and Retinal Layers in Multiple Sclerosis   Jiwon Oh, Elias Sotirchos, Shiv Saidha, Anna Whetstone, Min Chen, Scott Newsome, Kathleen Zackowski, Jerry Prince, Marie Diener-West, Daniel Reich, Peter Calabresi 4:15 p.m. S54.005 Cortical Lesions in Multiple Sclerosis Correlate with Retinal Pathology as Measured by Optical Coherence Tomography   Daniel Harrison, Anna Whetstone, Omar Al-Louzi, Peter Calabresi 4:30 p.m. S54.006 The Effect of Cardiovascular Risk Factors on Lesion Burden and Brain Atrophy in Multiple Sclerosis   Natalie Kappus, Bianca Weinstock-Guttman, Jesper Hagemeier, Cheryl Kennedy, Rebecca Melia, Ellen Carl, Deepa Ramasamy, Maryia Cherneva, Jackie Durfee, Niels Bergsland, Michael Dwyer, Channa Kolb, Murali Ramanathan, Robert Zivadinov 4:45 p.m. S54.007 Early Clinical and MRI Predictors of Time to Second Attack and Disability in Children with Acute Demyelinating Syndromes: Findings from a Prospective National Cohort Study   Leonard Verhey, Ruth-Ann Marrie, Amit Bar-Or, Dessa Sadovnick, Manohar Shroff, Douglas Arnold, Brenda Banwell

126

3:45 p.m. S55.003 Marijuana Use and the Risk of Ischemic Stroke: The Stroke Prevention in Young Adults Study   Tara Dutta, Kathleen Ryan, Yuching Cheng, Steven Kittner, John Cole 4:00 p.m. S55.004 Trends in Substance Abuse Preceding Stroke in Young Adults: An Update   Felipe De Los Rios La Rosa, Dawn Kleindorfer, Jane Khoury, Joseph Broderick, Kathleen Alwell, Charles Moomaw, Pooja Khatri, Opeolu Adeoye, Matthew Flaherty, Daniel Woo, Jane Eilerman, Simona Ferioli, Brett Kissela 4:15 p.m. S55.005 Thrombophilia in Young Patients with Cerebrovascular Disease. AISYF Study   Luciana Leon Cejas, Ricardo Reisin 4:30 p.m. S55.006 Long Distance Travel Potentiates Other Novel Risk Factors in PFO Related Strokes—“Economy Class Strokes”   MingMing Ning, D Sena, K Feeney, T Wickham, M Elia, W Deng, I Chou, J Hung, L Chen, I Inglessis-Azuaje, S Silverman, R Schainfeld, D McMullin, G Dec, E Lo, I Palacios, F Buonanno 4:45 p.m. S55.007 Oral Contraceptive Use and Incident Stroke in Women with Sickle Cell Disease   Taqi Zafar, Malik Adil, Muhammad Umair, Saqib Chaudhry, Amna Zarar, Muhammad Suri, Adnan Qureshi

3:15 p.m.–5:00 p.m.

S56 Anterior Horn Disease 3:15 p.m.  Presentation of Sheila Essey Award: An Award for ALS Research Recipient: Jeremy Shefner, MD, PhD Syracuse, NY

3:45 p.m. S56.003 HuR Is Essential for TDP43 Expression Through Posttranscriptional Mechanisms: Implications for Motor Neuron Toxicity and ALS   Liang Lu, Lei Zheng, Ying Si, Shin Oh, Peter King 4:00 p.m. S56.004 GGGGCC Repeat Expansion of C9ORF72 Is Toxic via Sequestration of RNA Binding Proteins and Consequent Disruption of RNA Splicing   Johnathan CooperKnock, Matthew Walsh, Adrian Higginbottom, J Robin Highley, Joanna Bury, Mark Dickman, Magnus Rattray, Paul Heath, Matthew Wyles, Paul Ince, Stephen Wharton, Stuart Wilson, Janine Kirby, Guillaume Hautbergue, Pamela Shaw 4:15 p.m. S56.005 The TREM2 Variant p.R47H Is a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis   Matthew Harms, Janet Cady, Erica Koval, Bruno Benitez, Craig Zaidman, Jennifer Jockel-Balsarotti, Peggy Allred, Robert Baloh, John Ravits, Ericka Simpson, Stanley Appel, Alan Pestronk, Alison Goate, Timothy Miller, Carlos Cruchaga 4:30 p.m. S56.006 Spinal Muscular Atrophy Phenotype Is Ameliorated Either by SMN Increase or Modulation of Secondary Cell Death Events with RNA Therapy   Giulietta Riboldi, Monica Nizzardo, Chiara Simone, Federica Rizzo, Margherita Ruggieri, Serena Pagliarani, Gianna Ulzi, Sabrina Salani, Andrea DalMas, Monica Bucchia, Emanuele Frattini, Giulia Stuppia, Francesca Magri, Nereo Bresolin, Franco Pagani, Giacomo Comi, Stefania Corti 4:45 p.m. S56.007 iPSC-derived Neural Stem Cells Ameliorate the Phenotype of Spinal Muscular Atrophy with Respiratory Distress Type 1 (SMARD1)   Stefania Corti, Chiara Simone, Monica Nizzardo, Federica Rizzo, Margherita Ruggieri, Sabrina Salani, Monica Bucchia, Paola Rinchetti, Chiara Zanetta, Irene Faravelli, Erika Monguzzi, Francesca Magri, Nereo Bresolin, Giacomo Comi

2O14 Scientific Abstract Listing and Annual Meeting Information

S57 Movement Disorders: Imaging 3:15 p.m. S57.001 Abnormal Transcallosal Motor Projections In Cervical Dystonia: An fMRI and Tractographic Analysis   Jeff Waugh, Jake Kuster, Jacob Levenstein, Woodman Sandra, Trisha Multhaupt-Buell, Makris Nikos, Lewis Sudarsky, Hans Breiter, Nutan Sharma, Anne Blood 3:30 p.m. S57.002 Dopamine Transporter Imaging in Essential Tremor With and Without Parkinsonian Features   Olga Waln, Ying Wu, Reid Perlman, Anh Kim Van, Juliet Wendt, Joseph Jankovic 3:45 p.m. S57.003 Diffusion Tensor Imaging as a Biomarker for REM Sleep Behavior Disorder and Parkinson’s Disease   Matthew Brodsky, John Grinstead, David Lahna, Jeffrey Pollock 4:00 p.m. S57.004 Midbrain Microstructural Atrophy Associated with Parkinson’s Disease Motor and Cognitive Symptoms Using 7-Tesla MRI   Kathleen Poston, Laura Santoso, Jeffrey Bernstein, Matthew Cruadhlaoich, David Everling, Sophie YorkWilliams, Michelle Fenesy, Michael Zeineh, Geoffrey Kerchner 4:15 p.m. S57.005 Exploring the Neural Circuitry of REM Sleep Behavior Disorder in Parkinson’s Disease Using Functional MRI   Samuel Bolitho, James Shine, Sharon Naismith, Ron Grunstein, Peter Bell, Simon Lewis 4:30 p.m. S57.006 The ‘Swallow Tail’ Appearance of the Healthy Nigrosome—a New Accurate Test of Parkinson’s Disease: a Case-Control and Retrospective Cross-Sectional MRI Study at 3T   Stefan Schwarz, Mohammed Afzal, Paul Morgan, Nin Bajaj, Penny Gowland, Dorothee Auer 4:45 p.m. S57.007 Mapping Regional Grey and White Matter Damage in Patients with Progressive Supranuclear Palsy Syndrome   Francesca Caso, Federica Agosta, Maria Antonietta Volontè, Daniele Martinelli, Lidia Sarro, Francesca Spagnolo, Andrea Falini, Giancarlo Comi, Massimo Filippi

S58 Aging, Dementia, and Cognitive and Behavioral Neurology: Clinical Aspects 3:15 p.m. S58.001 Alzheimer Patients Show Significant Disturbance in Water Influx Into CSF Space Strongly Supporting β-amyloid Clearance Hypothesis   Tsutomu Nakada, Hironaka Igarashi, Yuji Suzuki, Ingrid Kwee 3:30 p.m. S58.002 Medical Risk Factors For Frontotemporal Degeneration: Analysis of the NACC Uniform Dataset   Mariel Deutsch, Mario Mendez, Edmond Teng 3:45 p.m. S58.003 Cholesterol, Statins and the Risk of Dementia in the Oldest-Old: The 90+ Study   Marcella Evans, Claudia Kawas, Maria Corrada 4:00 p.m. S58.004 The Effect of Triglycerides on Cognitive Function in Aging Adults: A Cross-Sectional Study   Vishnu Parthasarathy, Darvis Frazier, Laura Jastrzab, Linda Chao, Helena Chui, Brianne Bettcher, Joel Kramer 4:15 p.m. S58.005 Association of Type 2 Diabetes Cognitive Impairment Is Mediated by Brain Atrophy   Rosebud Roberts, David Knopman, Scott Przybelski, Michelle Mielke, Kejal Kantarci, Vernon Pankratz, Yonas Geda, Bradley Boeve, Walter Rocca, Ronald Petersen, Clifford Jack 4:30 p.m. S58.006 Factor Scores for Brain Reserve, Alzheimer and Vascular Pathology Are Independent Risk Factors for Dementia in a Populationbased Cohort Study: The Kame Project   Amy Borenstein, James Mortimer, Eric Larson 4:45 p.m. S58.007 Impaired Cerebral Autoregualtion Is Associated with a Greater 7-year Decline in Gait Speed in an Elderly Population: The MOBILIZE Boston Study   Farzaneh Sorond, Sushmita Purkayastha, Lewis Lipsitz, Suzanne Leveille

Scientific Sessions 3:15 p.m. S59.001 Malformation Risks of Antiepileptic Drug Monotherapies in Pregnancy: An Update from the UK and Ireland Epilepsy and Pregnancy Registers   Ellen Campbell, Fiona Kennedy, Aline Russell, W Smithson, Linda Parsons, Beth Irwin, Brenda Liggan, Norman Delanty, Patrick Morrison, Stephen Hunt, John Craig, Jim Morrow 3:30 p.m. S59.002 Congenital Malformations in Infants Born to Women with Epilepsy at Boston Medical Center   Gina Deck, Alexandra Lovett, Neil Nadkarni, Georgia Montouris 3:45 p.m. S59.003 Drivers for Epilepsy Readmissions: A Retrospective Cohort Study   Tracie Caller, Jasper Chen, Jessica Harrington, Barbara Jobst 4:00 p.m. S59.004 Antiepileptic Drug Prescribing for OEF/OIFVeterans with New-onset Epilepsy: 2008-2010   Mary Jo Pugh, Anne Van Cott, Christine Baca, Megan Amuan 4:15 p.m. S59.005 Factors Independently Associated with Anxiety and Depression in Epilepsy   Heidi Munger Clary, Marla Hamberger 4:30 p.m. S59.006 Comparison of Heart Rate Variability Parameters Between Partial and Idiopathic Generalized Epilepsy Patients in the Interictal Period   Kadriye Agan, Aslihan Ergun, Altug Cincin, Damla Ozbek Cetinkaya, Hatice Omercikoglu Ozden, Alper Kepez, Osman Yesildag, Ipek Midi 4:45 p.m. S59.007 Influences of Temporal Lobe Epilepsy and Temporal Lobe Resection on Olfactory Function   Richard Doty, Isabelle Tourbier, Taehoon Kim, Jonathan Silas, Paul Moberg, Ashwini Sharan, Michael Sperling, Bruce Turetsky

S60 Child Neurology II 3:15 p.m. S60.001 Evidence of Impaired Age-expected Growth and Atrophy of the Cerebellum in Pediatric Patients with Monophasic Acquired Demyelinating Syndrome and Multiple Sclerosis   Katrin Weier, Vladimir Fonov, Bérengère Aubert-Broche, Douglas Arnold, Brenda Banwell, D. Collins

S61 Muscle Disease: Gene Therapy and Models 3:15 p.m. S61.001 Restoration of Dystrophin Expression in a Novel Duchenne Mouse Model, the Dup2 Mouse, by IresMediated Translation of a Highly Functional N-truncated Dystrophin Protein   Kevin Flanigan, Adeline Vulin-Chaffiol, Nicolas Wein, Paul Janssen

3:30 p.m. S60.002 Incidence of Early Seizures with Levetiracetam Prophylaxis in Children After Traumatic Brain Injury   Melissa Chung, Nicole O’Brien

3:30 p.m. S61.002 β-Sarcoglycan Gene Transfer Leads to Functional Improvement in a Model of LGMD2E   Eric Pozsgai, Danielle Griffin, Kristin Heller, Jerry Mendell, Louise Rodino-Klapac

3:45 p.m. S60.003 Incidence of Epilepsy Following Perinatal Stroke: A Prospective Cohort Study   Rebecca Ichord, Niharika Gupta, Michael Uohara, Lori Billinghurst, Daniel Licht, Lauren Beslow

3:45 p.m. S61.003 MicroRNA-29 Overexpression Delivered by Adeno-Associated Virus Suppresses Fibrosis in mdx:utrn +/Mice   Eric Meadows, Janaiah Kota, Vinod Malik, Reed Clark, Zarife Sahenk, Scott Harper, Jerry Mendell

4:00 p.m. S60.004 Viral Infections during Pregnancy: a Risk Factor for the Development of Concurrent Autism and Epilepsy in the Offspring   Raman Sankar, Andrey Mazarati, James Washington III, Eduardo Pineda, Don Shin

4:00 p.m. S61.004 AAV Gene Transfer Utilizing Homologous Overlap Vectors Mediates Functional Recovery of Dysferlin Deficiency   Patricia Sondergaard, Eric Pozsgai, Danielle Griffin, Jerry Mendell, Louise Rodino-Klapac

4:15 p.m. S60.005 Predictors of Outcome in a Large Cohort of Infantile Spasms of Unknown Cause   Christopher Yuskaitis, Maura Madou, Katherine Howell, Annapurna Poduri, Elliott Sherr

4:15 p.m. S61.005 Fhl1 W122S Knock-in Mice Manifest Late-onset Mild Myopathy   Valentina Emmanuele, Akatzuki Kubota, Beatriz Garcia-Diaz, Caterina Garone, Orhan H. Akman, Kurenai Tanji, Catarina Quinzii, Michio Hirano

4:30 p.m. S60.006 Pellagra-like Syndrome Proves to be a Variant of Xeroderma PigmentosumCockayne Syndrome and Niacin Confers Clinical Benefit   Mustafa Salih, Hadia Hijazi, Muddathir Hamad, Hamdy Hassan, Shinu Ansari, Fowzan Alkuraya 4:45 p.m. S60.007 Presurgical Evaluations in Children with Pathology Confirmed Focal Cortical Dysplasia   Anna Mrelashvili, Katherine Nickels, Elaine Wirrell, Lily Wong-Kisiel

4:30 p.m. S61.006 Impaired Muscle Regeneration in CAPN3-KO Mice Related to MicroRNA Dysregulation   Zarife Sahenk, Cilwyn Braganza, Lei Chen, Syed-Rehan Hussain, Eric Meadows, Sarah Lewis, Kevin Flanigan, K. Reed Clark, Jerry Mendell 4:45 p.m. S61.007 Mutations in Zaspopathy Cause Disruption of Actinin-Crosslinked Actin Filaments, the Core Structure of Skeletal Muscle Z-discs   Xiaoyan Lin, Janelle Ruiz, Ilda Bajraktari, Rachel Ohman, Robert Griggs, Kenneth Fischbeck, Ami Mankodi

S62 Cerebrovascular Disease and Interventional Neurology: Cognitive and Behavioral 3:15 p.m. S62.001 Post-Surgical Cognitive Outcomes   Tania Giovannetti, Molly Fanning, Sarah Ratcliffe, Catherine Price, Steven Messe, Ola Selnes, Michael Acker, Thomas Floyd, Wilson Szeto, Joseph Bavaria 3:30 p.m. S62.002 Antiphospholipid Antibodies, Brain Infarcts, and Cognitive and Motor Decline in Aging (ABICMA): Final Cerebral Infarct Results from a Community-Based, Longitudinal, Clinical-Pathological Study   Steven Levine, Zoe Arvanitakis, Robin Brey, Jacob Rand, Julie Schneider, Lei Yu, Sue Leurgans, David Bennett 3:45 p.m. S62.003 Elevated Blood Pressure and Risk of Incident Amnestic Mild Cognitive Impairment/Alzheimer’s Disease   Steven Edland, Guerry Peavy, David Salmon, Douglas Galasko 4:00 p.m. S62.004 Influence of Pre-Existing Cognitive Impairment on the Outcome of Stroke Patients Treated by Thrombolytic Therapy. Results of the OPHELIECOG Study   Kei Murao, Didier Leys, Solene Moulin, Yasushi Okada 4:15 p.m. S62.005 Early Depression Screening Is Feasible in Hospitalized Stroke Patients   Rahul Karamchandani, Farhaan Vahidy, Suhas Bajgur, Kim Yen Thi Vu, H. Alex Choi, Adeolu Oladunjoye, Robert Hamilton, Sean Savitz 4:30 p.m. S62.006 Pre-Existing and Incident Cerebral Microbleeds Are Associated with Progression of Ischemic Vascular Lesions   Saloua Akoudad, Mohammad Ikram, Peter Koudstaal, Albert Hofman, Wiro Niessen, Steven Greenberg, Aad Van Der Lugt, Meike Vernooij 4:45 p.m. S62.007 Comparing Semi-quantitative and Volumetric Measurements of MRI White Matter Hyperintensities: The Northern Manhattan Study   Carly Oboudiyat, Hannah Gardener, Chensy Marquez, Mitchell Elkind, Ralph Sacco, Charles DeCarli, Clinton Wright

S63 Neuromyelitis Optica and Autoimmune Encephalitis 3:15 p.m. S63.001 Revised Diagnostic Criteria for Neuromyelitis Optica Spectrum Disorders   Dean Wingerchuk, Brenda Banwell, Jeffrey Bennett, Philippe Cabre, William Carroll, Tanuja Chitnis, Jerome De Seze, Kazuo Fujihara, Benjamin Greenberg, Anu Jacob, Sven Jarius, Marco Lana-Peixoto, Michael Levy, Jack Simon, Silvia Tenembaum, Anthony Traboulsee, Patrick Waters, Kay Wellik, Brian Weinshenker 3:30 p.m. S63.002 Differentiating NMO and MSassociated Optic Neuritis by MRI   Maureen Mealy, Anna Whetstone, Peter Calabresi, Michael Levy 3:45 p.m. S63.003 Clinical and Demographic Features of Children with NMO: Report from the U.S. Network of Pediatric MS Centers of Excellence   Tanuja Chitnis, Jayne Ness, Lauren Krupp, Emmanuelle Waubant, Tyler Hunt, Moses Rodriguez, Timothy Lotze, Mark Gorman, Anita Belman, Bianca Weinstock-Guttman, Marc Patterson, John Rose, Charlie Casper 4:00 p.m. S63.004 AQP4-IgG Assays Comparison in Laboratory Clinical Serivce   James Fryer, Vanda Lennon, Sean Pittock, Sarah Jenkins, Stacey Clardy, Erika Horta, Eric Jedynak, Claudia Lucchinetti, Elizabeth Shuster, Brian Weinshenker, Dean Wingerchuk, Andrew McKeon 4:15 p.m. S63.005 Therapeutic Effect of Plasma Exchange (PLEX) in Neuromyelitis Optica (NMO): Immediate and Long Term Response   Moogeh Baharnoori, Marika Hohol, Katerina Pavenski, Paul O’Connor 4:30 p.m. S63.006 Neuromyelitis Optica Spectrum with Autoantibodies Against Myelin-Oligodendrocyte Glycoprotein have Distinct Clinical Features and Prognosis from Seronegative Patients   Douglas Sato, Dagoberto Callegaro, Marco Lana-Peixoto, Patrick Waters, Satoru Tanaka, Frederico Jorge, Toshiyuki Takahashi, Tatsuro Misu, Samira Apostolos-Pereira, Natalia Talim, Renata Simm, Angelina Lino, Ichiro Nakashima, Kyoichi Nomura, Masashi Aoki, Kazuo Fujihara 4:45 p.m. S63.007 From Behavior to Synapse: A Murine Model of Passive Transfer of Antibodies from Patients with Anti-NMDAR Encephalitis   Mannara Francesco, Javier Gutierrez Cuesta, Frank Leypoldt, Jesús Planagumà, Elena Martín García, Ankit Jain, Francesc Graus, Rita Balice-Gordon, Rafael Maldonado Lopez, Josep Dalmau



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127

Thursday May 1

S59 Epilepsy and Clinical Neurophysiology (EEG): Reproduction, Health Care Delivery, and Co-morbidities



Thursday, May 1 1

Current as of 2/13/2014

Controversies in Neurology Plenary Session

5:30 p.m.–7:00 p.m.

The program features experts discussing the most current and controversial issues in neurology. It is set up as a series of debates in which two speakers argue opposing sides of a single topic, followed by a rebuttal. Each round concludes with a 10-minute question and answer period. Moderators: Joseph Jankovic, MD, FAAN Member, Science Committee

Walter A. Rocca, MD, MPH Member, Science Committee; Chair, Clinical Research Subcommittee

Does Preventing Relapses Protect Against Progressive MS? Pro: Maria Trojano, MD University of Bari, Bari, Italy

Con: Helen Tremlett, PhD, BPharm University of British Columbia, Vancouver, BC, Canada

Is Intervention for Asymptomatic AVM Useful? Pro: Robert M. Friedlander, MD UPMC Presbyterian, Pittsburgh, PA

Con: J. P. Mohr, MD, FAAN Columbia University, New York, NY

Should Neurologists Prescribe Marijuana for Neurological Disorders? 

Pro: Barbara S. Koppel, MD, FAAN Metropolitan Hospital, Rye, NY

Con: John C. M. Brust, MD, FAAN New York Neurological Institute, New York, NY

For Full Abstracts and Bios for Plenary Speakers Visit AAN.com/view/SearchAM

128

2O14 Scientific Abstract Listing and Annual Meeting Information



Friday, May 2

Integrated Neuroscience Session

Proteinopathy in Neurodegenerative Disease

I11 

8:00 a.m.–12:00 p.m.

Coordinators: Carol F. Lippa, MD, and David G. Munoz, MD Invited Speaker Session:  8:00 a.m.–10:30 a.m. 8:00 a.m.–8:15 a.m.

Neurodegenerative Disease: Past, Present, and Future  David G. Munoz, MD

8:15 a.m.–8:45 a.m.

Bioenergetic Consequences of Protein Misfolding in Neurodegenerative Diseases  M. Flint Beal, MD, FAAN

8:45 a.m.–9:15 a.m.

Molecular Correlates of Alzheimer Progression  Bradley T. Hyman, MD, PhD

9:15 a.m.–9:45 a.m.

Alpha-Synuclein Associated Mechanisms of Neuronal Injury: The Mitochondrial Link  J. Timothy Greenamyre, MD, PhD

9:45 a.m.–10:15 a.m. Prion-like Diseases: The Future is Unfolding  Neil R. Cashman, MD 10:15 a.m.–10:30 a.m. Panel Discussion

Poster Rounds:  10:30 a.m.–11:30 a.m. I11-1.001 An Abeta Oligomer Receptor

Antagonist and Antibodies to Specific Target Receptor Epitopes Displace Abeta Oligomers in Alzheimer’s Patient Brain Tissue Sections  Susan Catalano, Nicholas Izzo, Courtney Rehak, Raymond Yurko, Kelsie Mozzoni, Colleen Silky, Gary Look, Gilbert Rishton, Hank Safferstein, Tara Spires-Jones

I11-1.002 Imaging Tau Pathology in

Vivo in FTLD: Initial Experience with (18F) T807 PET  Bradford Dickerson, Kimiko Domoto-Reilly, Daisy Hochberg, Michael Brickhouse, Michael Stepanovic, Keith Johnson

I11-1.003 A CSF Signature of

Frontotemporal Lobar Degeneration with C9orf72 Repeat Expansions  William Hu, Jonathan Glass, Vivianna Van Deerlin, Murray Grossman, Kelly Watts, James Lah, John Trojanowski, Allan Levey

I11-1.004 Progressive Supranuclear Palsy (PSP): Diagnosis Through Skin Biopsy  Ildefonso Rodriguez-Leyva, Ana Calderon-Garcidueñas, Martha Santoyo, Erika Chi, Verónica Medina-Mier, Maria Jimenez-Capdeville

I11-1.006 Complement Factor H Is a

Biomarker for Mild Cognitive Impairment Not Due to Alzheimer’s Disease Trung Nguyen, Kelly Watts, James Lah, Jonathan Glass, Allan Levey, William Hu

I11-1.007 Cytoplasmic Redistribution of Mutant TDP-43 in a BAC Based Mouse Model of Amyotrophic Lateral Sclerosis  Kevin Talbot, David Gordon, Ruxandra Mutihac, Javier AlegreAbarrategui, Lucy Farrimond, Ben Davies, Richard Wade-Martins

I11-1.005 Spinocerebellar Ataxias

I11-1.008 Coenzyme Q10, Statin, and

Spinocerebellar Ataxias  Sheng-Han Kuo, Raymond Lo, Karla Figueroa, Stefan Pulst, Susan Perlman, George Wilmot, Christopher Gomez, Jeremy Schmahmann, Henry Paulson, Vikram Shakkottai, Sarah Ying, Theresa Zesiewicz, Khalaf Bushara, Michael Geschwind, Guangbin Xia, S Subramony, Tetsuo Ashizawa

I11-1.009 Epigenetic Mechanisms Linking Diabetes and Synaptic Plasticity  Giulio Pasinetti

I11-1.010 PACAP Deficit in Alzheimer’s

with Hypogonadism: Unraveling a Novel Group of Inherited Neurometabolic Disorders  Charles Lourenco, Claudia Sobreira, Roberto Giugliani, Stephan Zuchner, Wilson Marques, Jr.

Disease and Protection Against BetaAmyloid Toxicity PengCheng Han, Zhiwei Tang, Jun-Xiang Yin, Thomas Beach, Eric Reiman, Jiong Shi

Data Blitz:  11:30 a.m.–12:00 p.m. 11:30 a.m.

1II-2.001

11:35 a.m.

1II-2.002

RER1: A Novel Regulator of AlphaSynuclein  Nikolaus McFarland, Hyo-Jin Park, Lauren Ricchiuti

HuR Is Essential for TDP-43 Expression Through Posttranscriptional Mechanisms: Implications for Motor Neuron Toxicity and ALS  Liang Lu, Lei Zheng, Ying Si, Shin Oh, Peter King

11:40 a.m.

1II-2.003

α-Synuclein in Red Blood Cells Is a potential Diagnostic Biomarker for Parkinson’s Disease  Rodolfo Savica, Roy Dyer, Michelle Mielke, Bryan Klassen, Bradley Boeve, George Klee, J. Ahlskog, Walter Rocca, Marina Ramirez-Alvarado

11:45 a.m.

1II-2.004

Isradipine Rescues Alpha-synuclein Toxicity in a Zebrafish Model of Parkinson’s Disease by Upregulating Autophagy  Mark Stahl, Shubhangi Prabhudesai, Aaron Lulla, Jeff Bronstein

11:50 a.m.

Education Program Syllabi Full text syllabi and program slides will be available electronically only—online or via the Annual Meeting mobile app. All registered attendees will receive an email notification once syllabi are available. 130

2O14 Scientific Abstract Listing and Annual Meeting Information

1II-2.005

GGGGCC Repeat Expansion of C9ORF72 Is Toxic Via Sequestration of RNA Binding Proteins and Consequent Disruption of RNA Splicing  Johnathan Cooper-Knock, Matthew Walsh, Adrian Higginbottom, J Robin Highley, Joanna Bury, Mark Dickman, Magnus Rattray, Paul Heath, Matthew Wyles, Paul Ince, Stephen Wharton, Stuart Wilson, Janine Kirby, Guillaume Hautbergue, Pamela Shaw

Plenary Session

Current as of 2/13/2014 

Clinical Trials Plenary Session

12:00 p.m.–1:30 p.m.

This mid-day session covers important clinical topics that affect patient care identified from other society meetings. The latest updates within several clinical trials conducted over the course of the last year will be presented with an open panel discussion at the conclusion. Moderators: Natalia Sana Rost, MD, FAAN Vice-Chair, Science Committee

The Idiopathic Intracranial Hypertension Treatment Trial: A Multicenter, DoubleBlind, Randomized Clinical Trial Comparing Acetazolamide and Placebo on Visual Outcome Michael Wall, MD, FAAN University of Iowa, Iowa City, IA

Anti-angiogenic Therapy for Glioblastoma: A Randomized, DoubleBlinded Phase III Trial of Bevacizumab in Newly Diagnosed Patients Mark R. Gilbert, MD The University of Texas MD Anderson Cancer Center, Houston, TX

TOPIC: Efficacy and Safety of Once-daily Oral Teriflunomide in Patients with First Clinical Episode Consistent With Multiple Sclerosis

Petra Kaufmann, MD Member/Federal Liaison, Clinical Research Subcommittee

FAST-MAG Trial in Acute Ischemic Stroke Jeffrey L. Saver, MD, FAAN UCLA School of Medicine, Los Angeles, CA

CGRP Monoclonal Antibody LY2951742 for the Prevention of Migraine: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study  avid Dodick, MD D Mayo Clinic, Phoenix, AZ

Randomized, Double-blind, Placebo-controlled Trial of ALD403: An Anti-CGRP Peptide Antibody in the Prevention of Frequent Episodic Migraine Peter Goadsby, MD, PhD University of California, San Francisco, CA

Aaron E. Miller, MD, FAAN Mt. Sinai School of Medicine, New York, NY

For Full Abstracts and Bios for Plenary Speakers Visit AAN.com/view/SearchAM



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131



Section Topic Controversies/ Integrated Neuroscience

Friday, May 2 S64  Section Topic Controversies: Pain: Methods of Treatment

1:00 p.m.–2:30 p.m.

1:00 p.m.–1:05 p.m. Introduction Guy Burrows, MD

1:50 p.m.–2:05 p.m.

Headache: Classification  Morris Levin, MD

1:05 p.m.–1:20 p.m.

Interventional Pain Procedures for Headache and Facial Pain Syndromes Charles Brock, MD

2:05 p.m.–2:25 p.m.

Panel Discussion

2:25 p.m.–2:30 p.m. Conclusion  Guy Burrows, MD

1:20 p.m.–1:35 p.m.

Pain Connection with Sleep Disorders  lon Avidan, MD, MPH A

1:35 p.m.–1:50 p.m.

Opioids in Neurology Practice C hristopher Gibbons, MD

Concussion in Sports and the Military

I12 

1:00 p.m.–5:00 p.m.

Coordinators: Anthony G. Alessi, MD, FAAN, and Jack W. Tsao, MD, DPhil, FAAN Invited Speaker Session:  1:00 p.m.–3:30 p.m. 1:00 p.m.–1:10 p.m. Introduction 1:10 p.m.–1:40 p.m.

Headaches Following Concussion  Tad Seifert, MD

1:40 p.m.–2:10 p.m.

Imaging Following Concussion  Gary Small, MD, PhD

2:10 p.m.–2:40 p.m.

Sleep Disturbances Following Concussion  Joseph Krainin, MD

2:40 p.m.–3:10 p.m.

Blast Effects Causing TBI and Role of Blast Sensors  Geoffrey Ling, MD, PhD, FAAN

3:10 p.m.–3:30 p.m.

Questions and Answers

Poster Rounds:  3:30 p.m.–4:30 p.m. I12-1.001 fMRI Neuropsychological

I12-1.004 Alterations in Network

I12-1.002 Etiology and Epidemiology of

I12-1.005 Structural Imaging

Battery for Athletes with Concussion  David Hubbard, Adam Hampshire, Adrian Owen

Traumatic Brain Injury in Relation to Gender Differences Among African American Patients  Lien Diep, Robert Farney, Stacy Cary-Thompson, Jean Belcourt, Robert Farney, Janaki Kalyanam, Annapurni JayamTrouth

I12-1.003 Is There Chronic Brain

Damage in Retired NFL Players? Neuroradiology, Neuropsychology and Neurology of 45 Retired Players   Ira Casson, David Viano, E. Mark Haacke, Zhifeng Kou, Danielle LeStrange

Dynamics Following Blast-Induced Mild Traumatic Brain Injury  Andrei Vakhtin, Paul Taylor, Corey Ford Correlations with Memory Assessment and Concussion in Retired NFL Athletes Kyle Womack, Jeremy Strain, Nyaz Didehbani, Heather Conover, Michael Kraut, Munro Cullum, John Hart

I12-1.006 Progressive Return

to Activity Following Acute mTBI: A Standardized Approach  Robert Labutta, Therese West, Helen Coronel, Katherine Helmick

I12-1.007 Axonal Injury,

Neuroinflammation and Amyloid Pathology After Traumatic Brain Injury: Making Connections to Neurodegeneration David Sharp, Gregory Scott, Ramlackasingh Anil, Hellyer Peter, Leech Robert, Federico Turkheimer, Paul Matthews, David Brooks

I12-1.008 Neural Correlates of

Cognitive Anosognosia in Veterans with Mild Traumatic Brain Injury (mTBI)  Mohammed Ahmed, Ihtsham Haq, Robin Hurley, Katherine Taber, Jared Rowland, Ruth Yoash-Gantz, Stephen Kramer

I12-1.009 Comparison of Headache

in OEF/OIF Veterans with Traumatic Brain Injury (TBI) Against Controls Matched for Age, Sex, Race, and Deployment Time  James Couch, Kenneth Stewart

I12-1.010 The King-Devick Test

Is Vastly Superior to the Symbol Digit Modalities Test as a Sideline Determinant of Concussion in Mixed Martial Arts Fighters  Daniel Kantor

Data Blitz Session:  4:30 p.m.–5:00 p.m. 4:30 p.m.

I12-2.001

Effect of Concussion and Blast Exposure on Clinical Symptoms Following Deployment of U.S. Military Personnel  Mikias Wolde, Briana Perry, Jay Haran, Justin Campbell, Alia Creason, Catalina Sher, Lauren Stentz, Jack Tsao

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4:35 p.m.

I12-2.002

The Natural History of Acute Recovery of Blast-induced Mild Traumatic Brain Injury: A Case Series During War  Jason Hawley, David Larres, Elizandro Gonzales, Walter Carr

4:40 p.m.

I12-2.003

4:45 p.m.

I12-2.004

Field Utilization of the Cleveland Clinic Concussion iPad Assessment Tool  Jay Alberts, Joshua Hirsch, Susan Linder, David Schindler Development of a Medical Device for the Rapid Assessment of Concussion  Donald Weaver, Ying Tam, Christopher Barden, Ryan D’Arcy, Love Kalra, Lauren Petley, Chen Wei

2O14 Scientific Abstract Listing and Annual Meeting Information

4:50 p.m.

I12-2.005

Vision Testing Is Additive to the Sideline Assessment of Sports-Related Concussion  Rachel Ventura, Zoe Marinides, Steven Galetta, James Clugston, Laura Balcer

Plenary Session

Current as of 2/13/2014 

Neurology Year in Review Plenary Session

5:30 p.m.–7:00 p.m.

This plenary session will feature six speakers, each focusing on the latest research that has happened in the last year within a specific subspecialty topic. Moderator: Lisa M. DeAngelis, MD, FAAN

Chair, Science Committee

Multiple Sclerosis

Movement Disorders

Anne H. Cross, MD Washington University School of Medicine, St. Louis, MO

Kathleen M. Shannon, MD Rush University Medical Center, Chicago, IL

Headache/Pain

Neurocritical Care

Peter Goadsby, MD, PhD UCSF, San Francisco, CA

David M. Greer, MD Yale University School of Medicine, New Haven, CT

Neuromuscular

Alzheimer’s Disease

Robert C. Griggs, MD, FAAN University of Rochester, Rochester, NY

Todd E. Golde, MD, PhD University of Florida, Gainesville, FL

For Full Abstracts and Bios for Plenary Speakers Visit AAN.com/view/SearchAM



Fast, Easy Registration Online  ·  AAN.com/view/AM14

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AANonDemand.com/premeeting

2O14 Annual Meeting On Demand AAN is pleased to offer three educational products to enhance your experience at this year’s Annual Meeting. 1.  Best Value: AAN Annual Meeting On Demand— is the comprehensive digital library of content with more

than 500 hours* of presentations from the 2014 AAN Annual Meeting educational programs (including the Syllabi on CD and Neurology Update On Demand library). Watch presenters’ slides while listening to fully synchronized audio as if you were actually attending each session. Features of AAN Annual Meeting On Demand include:

¡¡ Online access to content within 24 hours of live presentations ¡¡ Streaming content for viewing on iPad® and most mobile devices ¡¡ Companion portable hard drive for offline access (shipped after the meeting)

¡¡ Downloadable MP3 files for convenient on-the-go audio (listen in the car, or on your MP3 player) ¡¡ Advanced Search: Search any word on the slides and immediately jump to that part of the presentation

2.  Neurology Update On Demand— offers a paired-down library of approximately 70 hours* of presentations focused on the

latest updates in the field of neurology. Sessions in this online only catalog will be available within 24 hours of the live presentation. Save $100 or more off the list price (savings depend on membership status and registration category).

3.  Syllabi on CD— serves as a quick reference tool with syllabi summaries of more than 160 programs presented during the 2014 Annual Meeting for only $299.

* T otal hours of presentations available subject to speaker permissions.

Pre-order now to save with deep discounts. AAN Annual Meeting On Demand + Syllabi Online, Portable Hard Drive, Mobile Streaming

$1,599 (List Price) $599  (save $1,000) $699  (save $900) $399  (save $1,200) $899  (save $700)

Member Attendee before May 3, 2014 Nonmember Attendee before May 3, 2014 Junior Attendee before May 3, 2014 Non Attendee before May 3, 2014

Syllabi CD CD

Neurology Update Online, Mobile Streaming

$299 (List Price) $249  (save $50) $299 $99  (save $200) $299

$599 (List Price) $399  (save $200) $499  (save $100) $249  (save $250) $499  (save $100)

To lock in the best prices, purchase the AAN Annual Meeting on Demand when you register for the 2014 Annual Meeting at AAN.com/view/register

Order one of three ways: 1.

When you register for the Annual Meeting online you are able to conveniently add the on demand products you wish to purchase. Register for the Annual Meeting and purchase these on demand products at AAN.com/view/register.

2.

If you are not attending this year’s Annual Meeting, you are still able to purchase on demand products to see what you missed! Visit AANonDemand.com/PreMeeting to learn more and purchase.

3.

Or call us at (800) 501-2303 or (818) 844-3299. Monday–Friday, 6:00 a.m.–5:00 p.m. PST.

Fast, Easy Registration Online  ·  AAN.com/view/AM14

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Connect at Social Events There’s no better way to combine an evening of great fun and entertainment with unparalleled networking than to attend the Opening Party, Closing Party—or both. Whether you attend the Annual Meeting at the beginning of the week, or the end, the events are not-to-be-missed. Comedy Show: The Water Coolers 8:30 p.m.–10:00 p.m.

Opening Party Sunday, April 27

6:00 p.m.–10:00 p.m.

Join your friends and colleagues for an exciting evening filled with delicious food, beverages, and entertainment. Each registered meeting attendee will receive one free ticket to these events. Guest tickets are available through registration for $50. Neurobowl® 6:00 p.m.–8:00 p.m.

This popular event hosted by AAN former president Thomas R. Swift, MD, FAAN, is one of the Annual Meeting’s premier happenings. Neurobowl showcases the best and brightest in neurology competing for the coveted Neurobowl trophy in an entertaining game-show format.

Ever start your day with 300 meetings scheduled, 700 emails in your inbox, and a soccer game at 3:00? Join the Water Coolers, the music and comedy act E Entertainment calls “the hottest ticket in town,” for a hilarious evening of laughout-loud song and sketch comedy that answers the question “does this stuff happen to anyone else?”

Closing Party Friday, May 2

7:30 p.m.–9:00 p.m.

Celebrate the end of a great meeting with the Closing Party! Each registered meeting attendee will receive one free ticket to this event. Guest tickets are available through registration for $50. Musical Entertainment 7:30 p.m.–9:00 p.m.

NFL star-turned-singer—and Public Leadership in Neurology Awardwinner—Ben Utecht will enchant you with his inimitable vocal stylings. After winning a Super Bowl ring in 2007, his career ended unexpectedly after a traumatic brain injury in 2009. Many saw this as an ending, but Ben saw an opportunity to pursue another lifelong passion—singing.

Exhibit Hall Opening Reception Main Stage: JellyRoll 8:30 p.m.–10:00 p.m.

Don’t miss this high-energy, 11-piece band that will get your feet moving with a repertoire including material from the classics to the newest top 40 hits. Fronted by the JellyRoll vocalists, driven by The JellyRoll Horns and Philadelphia’s tightest rhythm section, the awardwinning JellyRoll has won over audiences from Madison Square Garden in New York City to the White House in Washington, DC, with their unique blend of dance music.

136

Monday, April 28

4:30 p.m.–6:30 p.m.

Attend the opening reception to mingle with fellow attendees and preview the latest products and services available in the neurologic industry. Light hors d’oeuvres and beverages will be served. The exhibits will be open at this time.

2O14 Scientific Abstract Listing and Annual Meeting Information



Current as of 1/31/2014 –Programs and dates are subject to change

American Academy of Neurology and American Brain Foundation Awards Luncheon Wednesday, April 30

12:00 p.m.–1:30 p.m.

Public Leadership in Neurology Award Winner Ben Utecht

Run/Walk For Brain Research Tuesday, April 29

6:30 a.m.–8:30 a.m.

Support research in neurology and join us for a 5k run or onemile walk along the Philadelphia waterfront. Both occasional and seasoned runners—and walkers—will enjoy this beautiful trek for a good cause. All proceeds will go to the American Brain Foundation to help support research. The race is open to all meeting attendees and their families. Water and refreshments will be available following the race. The registration fee is $25. More information about this event will be posted as it becomes available on AAN.com/view/AMEvents. Bus service to and from the race site will be provided. For registration and details, visit AAN.com/view/RunWalk or contact Andrew Halverson at [email protected] or (612) 928-6117.

Reunion/Alumni Meetings Reconnect with your peers and program directors, and network with your fellow alumni at various department reunion meetings occurring throughout the Annual Meeting. If your department is interested in hosting its alumni meeting during the 2014 Annual Meeting, reserve your meeting today at AAN.com/view/alumni or by contacting Tammi Sand at [email protected] or (612) 928-6136.

NFL star-turned-singer Ben Utecht will receive the American Brain Foundation’s 2014 Public Leadership in Neurology Award for his commitment to spreading the word about how concussions and traumatic brain injury have affected his life. After winning a Super Bowl ring in 2007, his career ended unexpectedly after a traumatic brain injury in 2009. Many saw this as an ending, but Ben saw an opportunity to pursue another lifelong passion—singing. Join AAN leaders as they honor the recipients of the 2014 AAN and American Brain Foundation Awards. From enterprising high school students to world-renowned researchers, this program recognizes some of the top accomplishments in neuroscience research. Past keynote speakers on the importance of neurologic diseases include Billy McLaughlin, Tedy Bruschi, Dame Julie Andrews, Cuba Gooding Jr., Leeza Gibbons, and Michael J. Fox. Tickets are available for $60 through registration. Students and Junior members of the AAN may attend this event at no cost by requesting a ticket. Buy a ticket and show your support for award recipients. Reserve a Department Table and Be Recognized

Bring your department together and gain exposure for your team at the Awards Luncheon by reserving a department table. Give your residents and fellows the chance to sit together with department faculty and chairs in a place of honor among the top minds in the neurology/neuroscience academic community. For questions, contact Laurie Dixon at [email protected] or (612) 928-6154.

Yoga Sessions Need to relax before a day filled with the latestbreaking science and the best in education? Yoga sessions will be offered Sunday and Monday from 6:30 a.m.-7:30 a.m. If you need to unwind after the day we will be offering a Wednesday evening Yoga session from 5:00 p.m.-6:00 p.m. The registration fee is $10 per session. For registration and details please visit AAN.com/view/AMEvents.



Fast, Easy Registration Online  ·  AAN.com/view/AM14

137



Highlights for Students, Residents, and Fellows The AAN Annual Meeting is an ideal setting for students, residents, and fellows to gain exposure to a variety of interests and career disciplines, as well as network with leading neurologists and neurology professionals from around the world.

Registration FREE for Medical Students

Annual Meeting registration is FREE to medical students, graduate students, and PhD candidates who present a student ID card or are AAN members. Only $100 for Junior Residents and Junior Fellows

2014 Medical Students, Residents, and Fellows Guide

Annual Meeting registration is only $100 (a $740 savings from nonmember neurologist registration!) before the April 3, 2014, early registration deadline.

Opportunities to Save Money Rush Line Tickets

Check in at the Registration Booth located in the Convention Center each morning for FREE tickets to Education Programs for that day. A minimum of two tickets will be held for each program available on a first-come, first-served basis.

nts, ical Stude 2014 Med llows Guide , and Fe Residents

Co nn ec tin

uro log g All of Ne

y

3, 2014 26 – Ma y • Ap ril hia , PA Phi lad elp

Get 50% Off Education Program Registration

Junior members who register for two Education Programs at full price will receive 50% off the cost of a third Education Program of equal or lesser value. Volunteer Opportunities

Serve as a program monitor or a workshop volunteer to gain free access to the specific program (see page 142).

A detailed guide highlighting all events and opportunities of interest to Students, Residents, and Fellows is available at AAN.com/view/resident.

“[The Annual Meeting Science Programs give me] a lot of exposure to different researchers and to different work that people do in the field of neurology. When you come to this place, you are exposed to everything: the cutting-edge science, the new techniques, the basically new science, the new indications, the new guidelines.” Mohamed El Hag, MD (Resident) Cleveland, OH

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2O14 Scientific Abstract Listing and Annual Meeting Information

There’s no better way to combine an evening of great fun and entertainment with unparalleled networking than to attend the Opening Party, Closing Party—or both! Whether you attend the Annual Meeting at the beginning of the week, or the end, these parties are not-to-be-missed.

Opening Party Sunday, April 27 6:OO p.m.–1O:OO p.m.

Join your friends and colleagues for an exciting evening filled with entertainment, including:

Neurobowl® 6:OO p.m.–8:OO p.m.

This popular event is one of the Annual Meeting’s premier happenings. Neurobowl® showcases the best and brightest in neurology competing for the coveted Neurobowl® trophy in an entertaining game-show format.

Main Stage Music: JellyRoll 8:3O p.m.–1O:OO p.m. Don’t miss this high-energy, 11-piece band that will get your feet moving with a repertoire including material from the classics to the newest top 40 hits. Fronted by the JellyRoll vocalists, driven by The JellyRoll Horns and Philadelphia’s tightest rhythm section, the award-winning JellyRoll has won over audiences from Madison Square Garden in New York City to the White House in Washington, DC, with their unique blend of dance music.

Comedy Show: The Water Coolers 8:3O p.m.–1O:OO p.m. Ever start your day with 300 meetings scheduled, 700 emails in your inbox, and a soccer game at 3:00? Join The Water Coolers, the music and comedy act E Entertainment calls “the hottest ticket in town,” for a hilarious evening of laugh-out-loud song and sketch comedy that answers the question “does this stuff happen to anyone else?”

Closing Party Friday, May 2 7:3O p.m.–9:OO p.m.

Musical Entertainment

Former NFL star-turned-singer and Public Leadership in Neurology Award-winner Ben Utecht will enchant you with his inimitable vocal stylings.



General Information CME/Accreditation/Core Competencies Accreditation

The American Academy of Neurology Institute (AANI), the education subsidiary of the American Academy of Neurology, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education (CME) for physicians. AMA Credit Designation

The AANI designates this live activity for a maximum of (*) AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. *See individual program descriptions in this booklet for the maximum number of credits per program. CME/Participation Records

knowledge, skills, and professional performance and relationships that a physician uses to provide services for patients, the public or the profession. The content of CME is the body of knowledge and skills generally recognized and accepted by the profession as within the basic medical sciences, the discipline of clinical medicine, and the provision of health care to the public. (HOD policy #300.988) Certified CME is defined as: 1. Nonpromotional learning activities certified for credit prior to the activity by an organization authorized by the credit system owner, or 2. Nonpromotional learning activities for which the credit system owner directly awards credit Accredited CME providers may certify nonclinical subjects (e.g., office management, patient-physician communications, faculty development) for AMA PRA Category 1 Credit™ as long as these are appropriate to a physician audience and benefit the profession, patient care, or public health.

AANI has mechanisms in place to record, and when authorized by the participating physician, verify participation in the CME activity. To receive CME for the Annual Meeting live program, participants must: (1) register for the program(s); (2) attend the program(s); (3) submit the evaluation form for the program(s). CME is given only when all three steps are completed. AAN member CME and participation transcripts are available approximately four to six weeks following the close of the meeting via the AAN’s NeuroTracker AAN.com/cmeand-moc/track-and-view-transcript/ . Nonmembers’ CME credits and participation transcripts will be sent via email.

CME activities may describe or explain complementary and alternative health care practices. As with any CME activity, these need to include discussion of the existing level of scientific evidence that supports the practices. However, education that advocates specific alternative therapies or teaches how to perform associated procedures, without scientific evidence or general acceptance among the profession that supports their efficacy and safety, cannot be certified for AMA PRA Category 1 Credit™.

Core Competencies

The AANI, as an ACCME accredited provider, is responsible for validating the clinical content of CME activities that it provides. Specifically, 1. All the recommendations involving clinical medicine in a CME activity must be based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the care of patients. 2. All scientific research referred to, reported or used in CME in support or justification of a patient care recommendation must conform to the generally accepted standards of experimental design, data collection and analysis.

The AANI develops its activities/educational interventions in the context of the desirable physician attributes. Specifically, the AANI develops its educational interventions in the contents of the Accreditation Council for Graduate Medical Education (ACGME) Core Competencies which include: ¡¡ Patient Care ¡¡ Practice-Based Learning and Improvement ¡¡ Medical Knowledge ¡¡ Professionalism ¡¡ Interpersonal and Communication Skills ¡¡ Systems-Based Practice For more information on the definitions of the ACGME core competencies, please consult the following webpage: www.acgme.org Once again, this year’s Annual Meeting CME offerings, at the program and lecture level, are identified according to these competencies. Through identifying individual programs by competencies, attendees can easily identify and attend programs that meet each core competency. AMA CME Definition/ Educational Content of Certified CME

The AMA HOD and the Council on Medical Education have defined continuing medical education as follows: CME consists of educational activities which serve to maintain, develop, or increase the 140

Content Validation

Disclaimers/Disclosures AAN/AANI Education/Scientific Disclaimer

The primary purpose of the Annual Meeting is to meet the educational needs of its members and address practice gaps by providing practice-oriented and scientifically based educational activities that will maintain and advance competence and performance in the field of neurology. A diversity of opinions exists in the medical field and the views of the Annual Meeting faculty do not represent those of the AAN/AANI or constitute endorsement by the AAN/AANI. The AAN/AANI disclaims any and all liability for the claims that may result from the use or nonuse of information, publications, therapies, and/or services discussed at the Annual Meeting.

2O14 Scientific Abstract Listing and Annual Meeting Information

Relationship Disclosure and Conflict of Interest Resolution

Internet Kiosks

According to AANI and ACCME policies, everyone who is in a position to control the content of an education activity must disclose financial relationships with any commercial interest to the provider. An individual who refuses to disclose relevant financial relationships is disqualified from being a planning committee member, a teacher, or an author of CME, and cannot have control of, or responsibility for, the development, management, presentation or evaluation of the CME activity. In addition, the AANI must implement a mechanism to identify and resolve all conflicts of interest prior to the education activity being delivered to learners. The resolution of conflict is handled by the Education and Science Committees. Disclosures for everyone in the position to control Annual Meeting content can be found on the AAN Annual Meeting website. In addition, education and science faculty disclosures can also be found in the syllabi, slides, handouts, and/or is done verbally from the podium. Unlabeled Use Disclosure

The AANI requires all Annual Meeting presenters to disclose if a therapy/product is not labeled for the use being discussed or if the therapy/product is still investigational. Unlabeled use disclosures can be found in the program materials. Education Grants

Some Annual Meeting education and scientific programs are supported in part by educational grants from commercial entities. Disclosure of the educational grant is done through acknowledgement statements on the program materials, signs outside of the room, and verbally from the podium. Although educational grants are received, all programs are developed and implemented solely by the Education Committee and Science Committee. The terms, conditions, and purposes of the commercial support are documented in a written agreement between the AANI and commercial supporter. The AAN uses grant funds to support and enhance existing, as well as new, education programs.

The internet kiosks provide attendees with computer workstations and Internet access. Check email, search the AAN website, or complete online evaluations to obtain CME Credit. Wireless Connection

Wireless Internet hotspots will be available at the Pennsylvania Convention Center. Business Center

The Pennsylvania Convention Center has a business center that offers administrative and office services, including copy machines, faxes, and shipping services. The business center is located on the lobby level of the Pennsylvania Convention Center. First Aid Station

A First Aid station is located on the lobby level of the Pennsylvania Convention Center. The station is staffed by licensed medical professionals and fully equipped with supplies, including automatic external defibrillators (AED). The station is operational throughout the duration of the Annual Meeting. Brain Food

During the 2014 Annual Meeting, attendees will be provided with light, brain healthy, meals throughout each day. Small break carts will be placed in an accessible area to allow attendees registered for paid Education Programs will be served a great tasting, healthy snack during the break time to keep all energized and ready to learn. Prayer Room

A prayer room will be available in the Convention Center for attendees looking for a quiet space for thought, reflection, and prayer. Mother’s Room

A private room will be available in the Convention Center for nursing mothers and others with sensitive personal health needs. Please note that this room will not be staffed.

Services

Guidelines

Child Care Information

Photography and Recording of Programs

A variety of child care options are available in Philadelphia. Check with the concierge at your hotel on or before your arrival to make your arrangements.

The AAN strictly prohibits all unauthorized photography (flash, digital, or otherwise), audio and/or video recording during the Annual Meeting. Equipment will be confiscated. Photography is allowed only in the Poster Sessions.

Luggage Check

No luggage check is available at the Pennsylvania Convention Center. Check with your concierge at your hotel to make your arrangements. Shuttle Service

Complimentary shuttle bus service will be provided between designated official AAN hotels and the convention center. Schedules will be available at the Pennsylvania Convention Center and will also be posted in each hotel lobby.



Consent to Use of Photographic Images

Registration and attendance at, or participation in, AAN/AANI meetings and other related activities constitutes attendee’s authorization to AAN’s use and distribution (both now and in the future) of the attendee’s image or voice in photographs, video recordings, electronic reproductions, audio recordings and other media throughout the world and royalty free.

Fast, Easy Registration Online  ·  AAN.com/view/AM14 141

General Information Cell Phones

The AAN requests that attendees turn cellular phones and pagers to vibrate mode upon entering all Annual Meeting programs. Language

The official language of the Annual Meeting is English. No simultaneous translation is available. No Smoking

The Pennsylvania Convention Center is a nonsmoking facility. For the health and comfort of everyone, smoking is prohibited at Annual Meeting functions, which include all education and scientific activities and social functions. Press Room

Only authorized media may use the Press Room at the Annual Meeting. Journalists must check in at the Press Room and provide proper credentials. For more information, contact Rachel Seroka at [email protected] or (612) 807-6968. Volunteer Opportunities Education and Scientific Program Monitors

RED: 14AM RunWalk Ad MonitorsNeurology are needed for alloreducation programPractice, offerings and scientific Placed in AANnews, Journal, Neurology Clinical AMRAP 8.25"x5.4375", Full Bleed +0.125", (BWdirectors, if in NJ) faculty, session co-chairs, and platform sessions to 4C assist

staff as required. The AAN will waive all monitors' Annual Meeting registration, registration fee for monitored program, as well as grant CME credit for the monitored program. Space is available on a firstcome, first-served basis. For an application form or more information, contact Laurie Dixon at [email protected] or (612) 928-6154. Skills Workshop Volunteers

Volunteers are needed to participate in the Neurophysiologic Intraoperative Monitoring Skills Workshop on Sunday, April 27. Volunteers are also needed to participate in the EMG Clinical Skills Workshop Monday, April 28, and the Neuromuscular Ultrasound Skills Pavilion on Friday, May 2. Skills workshop subjects will receive a waived meeting registration and workshop fee as well as payment of $40 per noninvasive session and $60 per invasive session. Space is available on a first-come, first-served basis. For more information, contact Elizabeth Busch at [email protected] or (612) 928-6115. Weather/Attire

The climate in Philadelphia in April is generally warm and pleasant. In April, temperatures usually range from 66 degrees to 73 degrees Fahrenheit. The AAN promotes business casual attire for the duration of the Annual Meeting. Consider bringing a light jacket or sweater to Annual Meeting activities since meeting room temperatures and personal comfort levels vary.

Run/Walk for Brain Research On your mark, get set…help cure BRAIN DISEASE! Join your colleagues on Tuesday, April 29, 2014, at 6:30 a.m., for a friendly run/walk. All proceeds will go to the American Brain Foundation to help support research. Sign up for the Run/Walk at AAN.com/view/RunWalk

Annual Meeting App Coming Soon! The Mobile App puts all the information you need conveniently on your phone or tablet: ¡ View your itinerary ¡ Find room locations ¡ Access program slides and syllabi ¡ More A LITE version is available now, which allows you to browse programs, speakers, and convention details. Full version to be available prior to the meeting. Available for iPhone®, iPad®, or Android ®

Sponsored by:



Registration

The field of neurology is rapidly changing, and there’s nowhere like the AAN Annual Meeting to make sure you’re up to date. The 66th AAN Annual Meeting in Philadelphia offers breakthrough research, exceptional education programs, and boundless networking opportunities. Log in to the registration site where you can: ¡¡ Register quickly and easily ¡¡ Make your hotel selection and reservation

¡¡ Create your itinerary incorporating your education programs, scientific sessions and other Annual Meeting events ¡¡ Print your schedule and not miss a thing at the meeting!

Ways to Save The Annual Meeting offers a great value for the quality and quantity of programming. Try some of these savings tips: ¡¡ Renew your AAN membership or join the AAN now for maximum savings on registration and course fees at AAN.com/view/membership . ¡¡ Register now to avoid increased rates after the April 3, 2014, early registration deadline. ¡¡ Purchase education programs individually or select the new BUY ALL registration option and register for any course of interest for one flat rate.*

Member Type

General Registration1 Before April 3, 2014

General Registration After April 3, 2014

Students

$0

$0

Senior

$0

$0

Honorary Member

$0

$0

Junior and Non-Neurologist Member (Junior Intern, Resident or Junior Fellow, Business Administrator, Non-Neurologist Clinician, Research Scientist, Research Coordinator)

$100

$130

Member Neurologist (Active, Associate, Fellow)

$305

$420

Nonmember

$610

$840

* Skills Workshops and Skills Pavilions excluded from BUY ALL pricing. Attendee must identify courses to be included as part of “BUY ALL” purchase. Courses are subject to closure due to reaching maximum capacity. BUY ALL registration option is only available prior to early registration deadline of April 3, 2014. 144

Course Fees

Early: $45-$350 On-Site: $45-$350 Early: $85-$460 On-Site: $105-$480 Early: $85-$460 On-Site: $105-$480 Early: $45-$350 On-Site: $45-$350 Early: $85-$460 On-Site: $105-$480 Early: $115-$615 On-Site: $135-$635

BUY ALL* Registration Option2 Before April 3, 2014

$400 $400 $400

$400

$1,000 $2,000

(includes meeting access only, education courses must be paid for individually) 2  (includes access to meeting and ability to register for courses at no additional cost) 1 

2O14 Scientific Abstract Listing and Annual Meeting Information

Three Easy Ways to Register Online Fast, easy online registration available at AAN.com/view/AM14

Online registration walks you step-by-step through completing your registration, reserving a hotel, and personalizing your itinerary with top-tier education courses, scientific sessions, special Annual Meeting events, and more!

Fax/Mail A printable registration form is available at AAN.com/view/register

Download and print a registration form to complete and mail or fax to: Deadline: April 3 Mail: AAN Registration/CMR 33 New Montgomery, Suite 1100 Registrations received after April 3, 2014, San Francisco, CA 94105 will be processed at a higher rate.

Questions

Online: Email:

AAN.com/view/register [email protected]

Fax: (415) 293-4071

Telephone US/Canada:  (800) 676-4226

International:  (415) 979-2283

Fees General Registration Fee

Cancellations/Refunds of Registration

The general registration fee is mandatory for all registrants and is determined by AAN member type. Attendees selecting the new BUY ALL option will have the general registration fee included in the price.

Until April 3, 2014 April 4–April 18, 2014 After April 18, 2014

Education Programs

Purchase programs individually or select the new BUY ALL option to register for any course of interest for one flat rate (Note: Skills Workshops and Skills Pavilions are excluded from the BUY ALL registration package.) In addition, Junior Members who register for two Education Programs at full price will receive 50% off the cost of a third education program of equal or lesser value. Changes in Education Programs

Select education programs carefully. An administrative fee of $20 ($30 after April 3, 2014) will be charged for program cancellations without a replacement program. Many programs and events are included with your registration. See page 6 for details. Cancelled or Closed Programs

Education programs may be closed due to reaching maximum capacity or cancelled due to insufficient enrollment. In the event of cancellation, registration for the cancelled course will be fully refunded. The AAN is not responsible for airfare, hotel, or other costs incurred by participants in the event of program or registration closure or cancellation.



Refund less $50 administrative fee Refund less $100 administrative fee No refund

¡¡ All cancellations must be submitted in writing to [email protected] or faxed to (415) 293-4071. ¡¡ No-shows will not receive a refund. ¡¡ Name substitutions are not permitted. ¡¡ No refunds will be processed for amounts of $20 or less. Special Accommodations Deadline: April 3

The Pennsylvania Convention Center and the AAN are in compliance with the Americans with Disabilities Act or Human Rights Code and strive to accommodate all visitors. Information booths, designated parking, and assisted listening devices are available. If you require special accommodation to attend the Annual Meeting, submit your request while registering online or contact Laurie Dixon no later than April 3, 2014, at [email protected] or (612) 928-6154. Kosher meals may be provided at any breakfast or lunch, and must be arranged on or before April 3, 2014, through the registration website or by contacting AAN Registration/CMR at [email protected], (800) 676-4226, or (415) 979-2283. There is a $50 surcharge per meal. On-site requests cannot be accommodated. Group Registration Deadline: March 26

Group registrations are those in which 10 or more individuals’ fees are paid for with one check or credit card. Special registration instructions are available online AAN.com/view/register or by contacting CMR’s Group Registration at (800) 676-4226 (US/Canada) or (415) 979-2283 (International). See page 114 for housing information. Fast, Easy Registration Online  ·  AAN.com/view/AM14 145



Hotel Reservations Why Book a Hotel Room Through the AAN? Booking your room through the official AAN housing company assures you are getting a room at the hotel that best fits your needs. You are also helping the AAN maintain consistent and competitive registration fees. The reason is simple. When a city is selected as the site for the AAN Annual Meeting, contracts are signed with several hotels reserving a specific number of rooms to be available for meeting attendees. If these rooms are not sold, the AAN is liable financially. Penalties incurred affect the overall costs of the Annual Meeting and what the AAN charges for registration, exhibit space, and other services.

Save on Hotel Reservations Take advantage of the AAN’s special hotel rates to make your trip more affordable. Annual Meeting hotel reservations are processed by Convention Management Resources (CMR). AAN Online Hotel Reservations AAN.com/view/BookHotel

The AAN makes it easy and convenient to book your hotel rooms for the 66th Annual Meeting. Booking online allows you to: ¡¡ Take advantage of the AAN’s special hotel rates ¡¡ View room descriptions, photos, and availability ¡¡ Access maps of hotel proximity to Annual Meeting locations Telephone Reservations

All correspondence, questions, and inquiries should be directed to CMR at: Phone: Hours: Credit card reservations only Monday–Friday US/Canada (800) 676-4226 6:00 a.m.–6:00 p.m.(PST) International (415) 979-2283

Deposits

¡¡ All hotels require a credit card guarantee or a check deposit of $300 (US dollars) per room and $500 (US dollars) per suite. Deposits will be credited towards your first night’s room and tax. ¡¡ No hotel reservation will be processed without a credit card guarantee or a deposit. ¡¡ Deposits are refundable up to seven days prior to arrival, after which there will be no refunds. ¡¡ Credit cards will be charged for one night’s room and tax if you fail to arrive on the confirmed date of arrival or if you fail to cancel your reservation at least seven days prior to arrival. Confirmations, Changes, and Cancellations

¡¡ You will receive your hotel confirmation from CMR. This is the only confirmation you will receive. ¡¡ Please check your arrival and departure dates on the confirmation carefully. ¡¡ After March 26, 2014, contact CMR to book a room. After this date, however, rooms are subject to availability. Note: Some hotels may charge a penalty for changes made to your departure date after you have checked in. Group Accommodations

Blocks of 10 or more sleeping rooms are considered a group. Fax your written request to (415) 293-4071 or email to [email protected] and you will be contacted by an AAN Housing Consultant. Additional Tax/Assessments

¡¡ Rates do not include the 15.5% hotel tax. ¡¡ An $8 per night assessment fee is included to offset the expense of the meeting.

146

2O14 Scientific Abstract Listing and Annual Meeting Information

Corporate Therapeutic Updates Tuesday, April 29, 2O14 and Wednesday, April 3O, 2O14 Starting at 7:00 p.m. Registration is free and open to registered Annual Meeting attendees. Representatives from the following companies invite you to an informational session on therapeutic updates. This program provides you the opportunity to learn about current therapies and projects in the corporate pipeline.

Tuesday, April 29

Wednesday, April 3O

Baxter Healthcare Multifocal Motor Neuropathy (MMN) Location: Loews Philadelphia Hotel Common Wealth

Biogen Idec Tecfidera® (dimethyl fumarate): An Interactive, Case-Based Presentation Location: Philadelphia Marriott Downtown Grand Ballroom Salon EF

Biogen Idec TYSABRI® (natalizumab) Label Update Location: Philadelphia Marriott Downtown Grand Ballroom Salon EF Eisai Inc Now Available: FYCOMPA™ (perampanel) as an Adjunctive Therapy for the Treatment of Partial-Onset Seizures in Patients 12 Years and Older Location: Loews Philadelphia Hotel Congress ABC Genzyme, A Sanofi Company The Evolving Treatment Paradigm: Individualizing MS Care Location: Sheraton Philadelphia Downtown Hotel Liberty CD Time: 7:00 p.m.–8:30 p.m. Genzyme, A Sanofi Company Challenging Cases in Neuromuscular Disorders: Shortening the Diagnostic Odyssey Location: Sheraton Philadelphia Downtown Hotel Liberty AB Time: 8:45 p.m.–10:00 p.m. Medtronic, Inc. DBS Therapy Innovation Reception Location: Philadelphia Marriott Downtown Liberty ABC Mylan Mylan Neurology: Patient-Focused, High Quality Medicines Location: Philadelphia Marriott Downtown Grand Ballroom Salon GH Teva CNS The Evolution of COPAXONE ® Location: Loews Philadelphia Hotel Regency Ballroom B

*Commitments as of February 3, 2014

Novartis Pharma AG Basel, Switzerland Time for Change: Evolution of Outcome Measures in MS Location: Philadelphia Marriott Downtown Grand Ballroom Salon GH

RSVP is recommended for these events. Please visit www.AAN.com/view/CTU for more information. No CME will be given by any accredited organization for the Corporate Therapeutic Updates, and the AAN cannot affirm claims pertaining to FDA off-label medication, research use of pre-FDA drugs, or other research information that might be discussed. Corporate Therapeutic Updates are corporate events.

Hotel Map and Amenities Rate

Smoke Free Hotel

Distance to Convention Center

$251–$271

Y

2.0 Blocks

Y

No Charge

1

No Charge

$159

N

1.0 Blocks

Y

No Charge

0

N/A

$229

N

6.0 Blocks

Y

$9.95

1

No Charge

$242

N

4.0 Blocks

Y

$9.95

1

No Charge

$189

Y

Adjacent

Y

No Charge

1

No Charge

$289

Y

4.5 Blocks

Y

$18.00

1

No Charge

$159–$169

Y

1.0 Block

Y

No Charge

0

No Charge

$239

Y

1.0 Block

Y

No Charge

1

No Charge

$184

Y

4.0 Blocks

Y

No Charge

0

N/A

$239

Y

1.0 Block

Y

No Charge

0

No Charge

$219

N

2.7 Miles

Y

No Charge

0

No Charge

$259

Y

8.0 Blocks

Y

$10.00

1

No Charge

$259

Y

9.0 Blocks

Y

$11.99

1

No Charge

$275

Y

6.0 Blocks

Y

$9.99

2

No Charge

$239–$264

Y

1.6 Miles

Y

$9.95

1

No Charge

$269

Y

2.3 Miles

Y

No Charge

1

No Charge

Hotel Name & Address

1100 Arch Street

Holiday Inn Express Midtown

1305 Walnut Street Home2 Suites

1200 Arch Street Homewood Suites University City

4109 Walnut Street Hotel Monaco

433 Chestnut Street Hotel Palomar

117 South 17th Street Hyatt at the Bellevue

200 South Broad Street

Hyatt Regency at Penn’s Landing

201 South Columbus Blvd Inn at Penn

Filber t 3600 Sansom St. Street

S

St

N 21st

N 22nd

St.

St.

St. N 23rd

K A MT R A

Chestnu

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S 20 th

Spruce

St.

St.

St

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S 22nd

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St.

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S 23rd

16

Ludlow

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76 Filber t

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11

Chestnu

32

St.

S 31st St

Ludlow

St.

Market

S 32nd

16

Hilton Garden Inn Center City

St.

15

1301 Race Street

S 33 th

14

Hampton Inn City Center

St.

13

1 Logan Square

S 34th

12

Four Seasons

St.

11

1201 Race Street

S 36 th

10

Four Points City Center

St.

9

1776 Benjamin Franklin Pkwy

S 37th

8

Embassy Suites Center City

.

7

237 Broad Street

rsit y Ave

6

Doubletree Center City

S Unive

5

1227 Race Street

St.

4

Days Inn Philadelphia Convention Center Hotel

S 39 th

3

21 North Juniper Street

St.

2

Courtyard Downtown

S 40 th

1

High Speed Business Number of On-Site Internet Cost Center Restaurants Fitness Center per Day



Current as of 1/31/2014 –Subject to change

Rate

Smoke Free Hotel

Distance to Convention Center

$259

N

9.0 Blocks

Y

No Charge

0

No Charge

$299

Y

3.0 Blocks

Y

No Charge

4

No Charge

$249–$279

Y

1.0 Block

Y

$12.95

1

No Charge

Hotel Name & Address Latham Hotel

17

135 South 17th Street Le Meridien

18

1421 Arch Street Loews

19

1200 Market Street

20

Omni Hotel at Independence Park

$259–$279

Y

1.0 Mile

Y

No Charge

1

No Charge

 21

Philadelphia Marriott Downtown Headquarter Hotel

$279–$299

Y

1.0 Block

Y

No Charge

1

No Charge

$218

Y

10.0 Blocks

Y

No Charge

3

No Charge

$251

Y

2.0 Blocks

Y

No Charge

0

No Charge

$279

Y

4.5 Blocks

Y

$9.95

1

No Charge

$219

Y

10.0 Blocks

Y

$12.95

1

No Charge

$209

Y

2.2 Miles

Y

No Charge

1

No Charge

$199

Y

9.0 Blocks

Y

$9.95

1

No Charge

$259

Y

8.0 Blocks

Y

$5.95

1

No Charge

$209

Y

5.0 Blocks

Y

No Charge

2

No Charge

$299

Y

5.0 Blocks

Y

$12.95

1

No Charge

$199

Y

1.0 Mile

Y

No Charge

1

No Charge

arlton S 99 South 17thWCStreet t.

t.

N 8th S

t.

t. N 9th S

t. N 6th S

N Colu Market

Chestnu

St.

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t St.

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95

20

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31

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St.

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N 7th S

19

Walnut S

St. Broad St. S 15th

S 16 th

St.

22 Pine St.

Junipe

14

Market

Arch S

St.

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St

9

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t.

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24

8

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S 13 th

St.

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13

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St. S 19 th

28

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400 Arch Street Vin

N 10 th

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 31

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30

mb u s

Callow

t.

1800 Market Street

N 2nd S

Sonesta

 29

t.

120 South 17th Street

Walnut S

t.

t.

Sofitel

 28

N 3rd S

1 Dock Street

S 2nd S

Sheraton Society Hill

 27

t.

3549 Chestnut Street

N 4th S

Sheraton University City

 26

t.

201 North 17th Street

S 3rd S

Sheraton Downtown

 25

t.

10 Avenue of the Arts

N 5th S

Ritz Carlton

 24

t.

1 East Penn Square

S 4th S

Residence Inn Center City

 23

t.

1701 South Locust Street

S 5th S

Radisson Blu Warwick

St.

1201 Market Street

N 11th

401 Chestnut Street

 22

St

High Speed Business Number of On-Site Internet Cost Center Restaurants Fitness Center per Day

27 15



Travel Information Reservations and Discounts The official travel agency for the Annual Meeting is Association Travel Pros. For 2%–10% discounted airline tickets to the Annual Meeting, contact them at: Phone: (877) 309-4330 Email: [email protected] Hours: Monday–Friday, 8:30 a.m.–5:30 p.m. CST Closed weekends and holidays A $25 service fee will be assessed per ticket for reservations made via phone. You may also book online with all airline meeting discounts applied at www.aantvlmeetings.com . A $10 service fee will apply to online bookings.

Direct Through Airlines

You may also contact your preferred airline directly. You must reference the AAN Annual Meeting and provide the appropriate airline discount codes listed below. Airline Discount Codes Phone Number Website American A7544AG* Delta NMGW2 United ZQVV245289

(800) 433-1790 (800) 328-1111 (800) 521-4041

www.aa.com www.delta.com www.united.com

Discounts are subject to availability, so book well in advance. Normal mileage and status upgrades apply for all airline programs. A service fee will be charged for reservations made via phone. Travel Website

For travel forms and information updates, visit the AAN Annual Meeting website at AAN.com/view/AM14. * Please use discount code 7544AG for travel direct through www.aa.com.

Travel Tips Travel Documents/Passports and Entry Requirements

Non-US visitors must have valid travel documents/passports to enter Philadelphia to provide proof of their citizenship. Document requirements vary depending on your country of origin, citizenship, the reason for your visit, and the length of your stay, and may include passport or a birth certificate, photo ID, and/or a visa. For more information, or to request a Letter of Announcement for the 2014 Annual Meeting, visit AAN.com/view/AMinfo. Currency

Philadelphia’s currency is the US dollar; currency exchange is available at banks and kiosks throughout the city and at the airport. Cash machines/ATMs are available in most banks, hotels, and shopping centers. For denominations under one dollar, the currency is coins. Customs and Immigration

From an international point of arrival, upon arriving in Philadelphia, you will be required to go through a US Customs and Border Protection (CBP) inspection. Before you land, your flight crew will distribute an Immigration and Customs Declaration Form for you to complete; forms are also available at the airport upon your arrival. You will need to present this form, along with your passport, visa (if any), and return tickets to the CBP officer.

150

Measurements

Philadelphia uses the United States customary system for weights and measurements. If you choose to drive in Philadelphia, be aware the speed limits are posted in miles per hour. Medication

If you are entering Philadelphia with prescription drugs and syringes: keep the medication in its original, labeled container; include medical certificate with syringes showing they are for medical use and have them declared to US Customs officials; bring an extra prescription in case your medication is lost and/or to attest to your need to take such prescriptions; and carry the generic name of prescription medicines. Time Zone

Philadelphia is in the Eastern Standard Time Zone. In April it will be the same time as New York, one hour ahead of Chicago, three hours ahead of Los Angeles, five hours behind London, and 13 hours behind Tokyo. For more information, visit AAN.com/view/AMinfo.

2O14 Scientific Abstract Listing and Annual Meeting Information

2O14 Annual Meeting Supporters The American Academy of Neurology and the American Brain Foundation thank the following companies, foundations, and organizations for their demonstrated vision, commitment, and strong support of programs which find answers and improve lives through neurologic education and research. ACTRIMS

¡ Exhibit Guide

The Allergan Foundation ¡ Minority Scholars Program & Visiting Professor Program

Allergan, Inc. ¡ ¡ ¡ ¡ ¡ ¡ ¡

C18 Therapy of Headache C81 Chronic Migraine Education Program AANextra Brain Health Fair – Gold Event Sponsor Exhibit Guide Presentation Stage Residents and Fellows Career Forum and Reception

Athena Diagnostics ¡ Exhibit Hall Passport

Baxter

¡ Corporate Therapeutic Update (4/29) ¡ Exhibit Hall Passport

Biogen Idec ¡ ¡ ¡ ¡ ¡ ¡ ¡ ¡ ¡

5K Run/1K Walk for Brain Research Annual Meeting Mobile App Brain Health Fair – Gold Event Sponsor Corporate Therapeutic Update (4/29 and 4/30) Emerging Leaders Forum Exhibit Hall Coffee Break (5/1) Exhibit Hall Opening Reception Footprints Residents and Fellows Career Forum and Reception

Eisai Inc.

¡ Corporate Therapeutic Update (4/29) ¡ Exhibit Hall Passport

ElectroCore

¡ Exhibit Hall Passport

Eli Lilly and Company

¡ Emerging Leaders Forum

EMD Serono, Inc.

¡ Exhibit Hall Passport ¡ Resident Scholarship Fund

Geisinger Health System ¡ Exhibit Hall Passport

Genzyme, a Sanofi Company ¡ ¡ ¡ ¡ ¡ ¡ ¡ ¡ ¡ ¡ ¡ ¡ ¡

5K Run/1K Walk for Brain Research AANextra Brain Health Fair – Silver Event Sponsor Buy A Brain® campaign Carpet Marketing Corporate Therapeutic Update (2) (4/29) Door Drop Insert (4/28) Exhibit Guide Fellow Scholarship Fund Pillar Wrap Posters Online Presentation Stage Resident Scholarship Fund

The HCA Earn While You Learn Stipend Program ¡ Resident and Fellow Scholarship Fund

Ipsen Biopharmaceuticals, Inc.

¡ C28 Botulinum Toxins: Practical Issues and Clinical Uses for Neurologists ¡ C53 Clinical Usefulness of Botulinum Toxin and Treatment of Dystonia Skills Pavilion

Kronus, Inc.

¡ Exhibit Guide

Lundbeck LLC ¡ ¡ ¡ ¡

AANextra Door Drop Insert (4/28) Exhibit Hall Cell Phone Charging Station Exhibit Hall Passport

Medtronic, Inc. ¡ ¡ ¡ ¡

C95 Deep Brain Stimulation Management Corporate Therapeutic Update (4/29) Door Drop Insert (4/28) Presentation Stage

Merck & Co., Inc.

Brain Food Station (4/30) Door Drop Insert (4/28 and 4/29) Exhibit Guide Exhibit Hall Cell Phone Charging Stations (2) Exhibit Hall Coffee Breaks (4/29 and 4/30) Exhibit Hall Internet Center (2) Exhibit Hall Footprints Exhibit Hall Pillar Wrap Exhibit Hall Passport Presentation Stage

Supernus Pharmaceuticals, Inc. ¡ Door Drop Insert (4/28) ¡ Exhibit Guide ¡ Exhibit Hall Passport

Teva CNS ¡ ¡ ¡ ¡ ¡ ¡ ¡ ¡ ¡

Merz Pharmaceuticals LLC ¡ Women in Leadership Program

5K Run/1K Walk for Brain Research Brain Health Fair – Gold Event Sponsor Corporate Therapeutic Update (4/29) Emerging Leaders Forum Hotel Key Cards C99 Epilepsy Skills Pavilion C157 Therapy of Epilepsy Brain Health Fair – Silver Event Sponsor Exhibit Hall Passport

Walgreens Infusion Services

Mylan

Corporate Therapeutic Update (4/29) Exhibit Guide Exhibit Hall Passport Presentation Stage The Resident Experience

Novartis Pharmaceuticals Corporation ¡ ¡ ¡ ¡ ¡ ¡

¡ ¡ ¡ ¡ ¡ ¡ ¡ ¡ ¡ ¡

Upsher-Smith Laboratories, Inc.

¡ C10 Approach to Sleep Symptoms: Sleepy or Sleepless ¡ C147 Dementia Update

¡ ¡ ¡ ¡ ¡

Sunovion Pharmaceuticals Inc.

Airport Dioramas Corporate Therapeutic Update (4/30) Exhibit Guide Taxi Tops Wayfinding Kiosk Wi-Fi Access

PSAV - Presentation Services ¡ Neuro Film Festival®

Questcor Pharmaceuticals, Inc. ¡ Exhibit Hall Passport

¡ Exhibit Hall Passport

Wolters Kluwer Health/Lippincott Williams & Wilkins, publisher of the

AAN publications Neurology ®, Neurology ®Clinical Practice, Neurology ®Neuroimmunology & Neuroinflammation, Continuum: Lifelong Learning in Neurology ®, Neurology Today ®, and Neurology Now ® ¡ ¡ ¡ ¡ ¡ ¡ ¡

Book Bags Brain Health Fair—Silver Event Sponsor Exhibit Hall Cell Phone Charging Station Exhibit Hall Internet Center Resident Scholarship Fund Shuttle Buses Transit Shelters

XenoPort, Inc.

¡ Door Drop Insert (4/28)

Regency Therapeutics, a Division of Luitpold Pharmaceuticals ¡ Door Drop Insert (4/29)

* Commitments received as of January 31, 2014



Exhibitor Listing AbbVie ABCN/ABRET Acorda Therapeutics, Inc. ACRM/American Congress of Rehabilitation Medicine ACTRIMS Akorn Pharmaceuticals Allergan, Inc. Alzheimer’s Association American Association of Neuromuscular and Electrodiagnostic Medicine American Board of Psychiatry & Neurology American Headache Society American Neurological Association American Physician Institute American Society for Apheresis (ASFA) Athena Diagnostics, Inc. Aurora Health Care Avanir Medical Affairs Avanir Pharmaceuticals, Inc. AxelaCare Health Solutions Balanceback Banner Health Baxter Healthcare Bayer HealthCare Benign Essential Blepharospasm Research Foundation, Inc. Biogen Idec Biomed Pharmaceuticals Blackrock NeuroMed Cadwell Cambridge University Press Captureproof, Inc. Carle Physician Group Catalyst Pharmaceutical Partners, Inc. Charleston Area Medical Center Child Neurology Foundation Cleveland Clinic CNS Vital Signs Community Health Systems Compumedics USA CRC Press / Taylor & Francis Group Critical Care Assessment Cytokinetics Dementia Society of America

152

Current as of 1/31/2014 –Programs and dates are subject to change

Demos Medical Publishing DENT Neurologic Institute Depomed, Inc. DigiTrace EEG Services DynaMed/EBSCO Dysautonomia International Dystonia Medical Research Foundation EFNS-ENS Eisai Inc. Electrical Geodesics, Inc. (EGI) Electro-Cap International, Inc. ElectroCore Elsevier, Inc. EMD Serono, Inc. Forest Pharmaceuticals, Inc. FR Carrick Research Institute GBS/CIDP Foundation International GE Healthcare Geisinger Health System GeneDx Genentech,INC Genzyme Genzyme Corporation Global Neuro-Diagnostics Great Lakes NeuroTechnologies Grifols USA Hayes Locums Hospital Corporation of America (HCA) IcoMetrix Impeto Medical Interacoustics International Essential Tremor Foundation (IETF) International Parkinson and Movement Disorder Society (MD) Intrafusion IPSEN Biopharmaceuticals, Inc. Jackson & Coker Jari Electrode Supply Jari Electrode Supply KabaFusion Kadlec Health System Karger Publishers KEGO FMI Kennedy Krieger Institute Kronus, Inc.

La Lettre Du Neurologue LocumTenens. com Lundbeck Magstim Mallinckrodt Pharmaceuticals Max Neuro Supply Inc. Mayo Medical Laboratories McGraw-Hill Medical Neurogenetics MedLink Corporation Medtronic, Inc. Merz Neurosciences Ministry Health Care MotherToBabystudies Conducted By the Organization of Teratology Information Spec MS Coalition Multigon Industries, Inc. Multiple Sclerosis Association of America Multiple Sclerosis Foundation Mylan Inc. National Ataxia Foundation National Institute of Neurological Disorders and Stroke (NINDS) National Multiple Sclerosis Society Natus Neurology Incorporated Nervline-NeurologicDx Neurology Reviews Neurovirtual USA, Inc. Nihon Kohden America, Inc. Norton Healthcare Physician Services Novartis Pharma AG Novartis Pharmaceuticals Corporation Ochsner Health System Opexa Therapeutics Otometrics Oxford University Press Parkinson’s Action Network Pfizer Inc. Physicians Committee for Responsible Medicine Pikeville Medical Center, Inc. Piramal Imaging Polar Products Inc. Practical Neurology PracticeLink. com

2O14 Scientific Abstract Listing and Annual Meeting Information

PracticeMatch Services LLC PRC Clinical ProtoKinetics, LLC Providence Health & Services Questcor Pharmaceuticals, Inc. Regency Therapeutics, a Division of Luitpold Pharmaceuticals Rochester Electro-Medical, Inc. RosmanSearch, Inc. RRS Salem Health Sensonics Int’l Soothe Personalized Medicine Rx Southeast Health Spastic Paraplegia Foundation SpecialtyCare Spectrum Health Medical Group Springer St. Luke’s University Health Network Sunovion Pharmaceuticals Inc. Supernus Pharmaceuticals, Inc. Synapse Biomedical, Inc Tenet South Florida—Advanced Neuroscience Network TEVA Neuroscience, Inc. The Electrode Store The Guthy-Jackson Charitable Foundation The JAMA Network Tourette Syndrome Association Transgenomic, Inc UCB, Inc. United Council for Neurologic Subspecialties (UCNS) Upsher-Smith Laboratories, Inc. US WorldMeds Vanda Pharmaceuticals Inc. VISTA Staffing Solutions Walgreens Infusion Services Wiley Wolters Kluwer Health World Association of Sleep Medicine (WASM) WR Medical Electronics XenoPort, Inc.

2O14 Corporate Roundtable Members* Corporate Roundtable support enables the American Academy of Neurology and the American Brain Foundation to improve patient care through their support of neuroscience research, education, and patient outreach.

$40,000

$30,000 Supernus Pharmaceuticals, Inc.

$20,000 Acorda Therapeutics, Inc.

Medtronic, Inc.

Amgen, Inc.

Piramal Imaging

Baxter Healthcare Corporation

Questcor Pharmaceuticals, Inc.

Eisai Inc.

Sunovion Pharmaceuticals Inc.

EMD Serono, Inc.

Upsher-Smith Laboratories, Inc.

*Commitments as of January 31, 2014

July 11–13 • Chicago, IL

Shining the Spotlight on Concussion Research Chicago, IL • July 11–13, 2014

Register Now! AAN.com/view/ConcussionConference

66th Annual Meeting Committee Members Meeting Management Committee

Stefan M. Pulst, MD, FAAN, Chair Timothy A. Pedley, MD, FAAN, AAN President Terrence L. Cascino, MD, FAAN, AAN President Elect Brenda Banwell, MD Neil A. Busis, MD, FAAN Cynthia L. Comella, MD, FAAN John Corboy, MD, FAAN Lisa M. DeAngelis, MD, FAAN Mill Etienne, MD, MPH, CPH Jonathan P. Hosey, MD, FAAN Carlayne E. Jackson, MD, FAAN Ralph F. Józefowicz, MD, FAAN Jennifer R. Molano, MD John C. Morris, MD, FAAN Ronald C. Petersen, PhD, MD Michael Pursel, Bpharm, MBA, FASCP Maisha T. Robinson, MD Stephen M. Sergay, MB BCh, FAAN Bruce Sigsbee, MD, FAAN Thomas R. Swift, MD, FAAN Education Committee

Cynthia L. Comella, MD, FAAN, Chair Steven L. Lewis, MD, FAAN, Vice Chair Allen J. Aksamit Jr., MD, FAAN Imran I. Ali, MD, FAAN Allison Brashear, MD, FAAN Bruce A. C. Cree, MD, PhD, MCR Barry M. Czeisler, MD John W. Engstrom, MD, FAAN Charles C. Flippen II, MD, FAAN Blair Ford, MD, FAAN J. Clay Goodman, MD, FAAN Laurie Gutmann, MD, FAAN Jonathan P. Hosey, MD, FAAN Jaffar Khan, MD, FAAN Rebecca K. Lehman, MD Janis Miyasaki, MD, FAAN Mark L. Moster, MD, FAAN Bruce I. Ovbiagele, MD, MSc, FAAN Lori Ann Schuh, MD, FAAN Joseph I. Sirven, MD, FAAN A. Gordon Smith, MD, FAAN

Science Committee

Practice Committee

Lisa M. DeAngelis, MD, FAAN, Chair Natalia Sana Rost, MD, Vice Chair Gregory K. Bergey, MD, FAAN Edward H. Bertram, MD David Q. Beversdorf, MD Paul M. George, MD, PhD, MSE Neill R. Graff-Radford, MD, FAAN Joseph Jankovic, MD, FAAN Eric Klawiter, MD Walter J. Koroshetz, MD, FAAN Catherine Lomen-Hoerth, MD, PhD Randolph S. Marshall, MD, FAAN Mark F. Mehler, MD, FAAN Jose G. Merino, MD, M.Phil Massimo Pandolfo, MD Rosebud Roberts, MD Walter A. Rocca, MD, MPH Nina F. Schor, MD, PhD Ericka P. Simpson, MD Mark H. Tuszynski, MD, PhD Barbara G. Vickrey, MD, MPH, FAAN Aleksandar Videnovic, MD, MSc Ryan Walsh, MD, PhD

Jonathan P. Hosey, MD, FAAN, Chair Heidi B. Schwarz, MD, FAAN, Vice-Chair Wayne E. Anderson, MD Carmel Armon, MD, FAAN Sarah M. Benish, MD Bruce H. Cohen, MD, FAAN Richard M. Dubinsky, MD, MPH, FAAN Miriam L. Freimer, MD Joseph V. Fritz, PhD Larry B. Goldstein, MD, FAAN, FAHA Raghav Govindarajan, MD Cynthia L. Harden, MD Anna D. Hohler, MD, FAAN Donald J. Iverson, MD, FAAN Michael J. Kaminski, MD, FAAN David J. Likosky, MD, SFHM Pushpa Narayanaswami, MBBS, MD, FAAN Marilyn M. Rymer, MD Don B. Smith, MD, FAAN James C. Stevens, MD, FAAN Jack W. Tsao, MD, DPhil, FAAN Raissa Villanueva, MD David Z. Wang, DO, FAHA, FAAN

Medical Economics and Management Committee

Abstract Reviewers

Orly Avitzur, MD, MBA, FAAN, Chair Gregory J. Esper, MD, MBA, Vice-Chair Neil A. Busis, MD, FAAN Allison Brashear, MD, FAAN Bruce H. Cohen, MD, FAAN Peter D. Donofrio, MD, FAAN David A. Evans, MBA Terry D. Fife, MD, FAAN William S. Henderson, FACMPE Jonathan P. Hosey, MD, FAAN Lyell K. Jones, MD Joel M. Kaufman, MD, FAAN Constantine Moschonas, MD John Ney, MD Marianna V. Spanaki, MD, PhD



Alex Abou-Chebl, MD Andrew H. Ahn, MD, PhD Yama Akbari, MD,PhD Roger L. Albin, MD Phillip J. Albrecht, PhD Roy Alcalay, MD Jason Lamar Aldred, MD Beau M. Ances, MD, PhD, MS Liana Apostolova, MD Charles E. Argoff, MD Misha-Miroslav Backonja, MD Alison Baird, FRACP, PhD, MBBS,MPH Laura J. Balcer, MD, MSCE, FAAN Brenda Banwell, MD Sergio Baranzini, PhD Amit Bar-Or, MD, FRCPC Kevin M. Barrett, MD A. M. Barrett, MD Tracy T. Batchelor, MD, MPH E Martina Bebin, MD

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66th Annual Meeting Committee Members Joseph R. Berger, MD, FAAN Bibiana Bielekova, MD Kevin M. Biglan, MD Arnaud Biraben, MD Gretchen L. Birbeck, MD, MPH, DTMH, FAAN Karen Ann Blindauer, MD Christopher J. Boes, MD James H. Bower, MD, MSc K.C. Brennan, MD Jeffrey W. Britton, MD Matthew A. Brodsky, MD Amy Brodtmann, MD, PhD, FRACP Krzysztof Bujarski, MD Rami Burstein, PhD Cheryl Bushnell, MD, MHS Peter A. Calabresi, MD, FAAN Patrizia Casaccia, MD, PhD Sydney Cash, MD John N. Caviness, MD, FAAN Antonia Ceccarelli, MD Marc Chamberlain, MD, FAAN Seemant Chaturvedi, MD, FAAN, FAHA Tanuja Chitnis, MD Tracey Cho, MD Emma Ciafaloni, MD, FAAN Adam B. Cohen, MD Amy Colcher, MD Greg Cole, PhD Giacomo Pietro Comi, MD Francis X. Conidi, MD, DO Wayne T. Cornblath, MD, FAAN Fiona Evann Costello, MD Patricia K. Coyle, MD, FAAN Claire Creutzfeldt, MD Ricardo Cruciani, MD Kevin E. Crutchfield, MD Nabila Dahodwala, MD Debra G. Davis, MD Philip De Jager, MD, PhD Stephanie Debette, MD, PhD Suhayl S. Dhib-Jalbut, MD, FAAN Alan Lee Diamond, DO Bradford Dickerson, MD Mazen M. Dimachkie, MD, FAAN Barbara A. Dworetzky, MD 156

P. James B. Dyck, MD, FAAN Eric R. Eggenberger, DO, FAAN Deniz Erten-Lyons, MD Amelia Evoli, MD Stewart A. Factor, DO, FAAN Samuel A. Frank, MD Johanna Therese Fifi, MD Elizabeth Fisher, PhD Kevin M. Flanigan, MD, FAAN Roy L. Freeman, MD Deborah I. Friedman, MD, FAAN Jennifer A. Frontera, MD Jessica Gautreaux, MD Frank G. Gilliam, MD, MPH Darren R. Gitelman, MD Christopher Glisson, DO Alica M. Goldman, MD Jennifer G. Goldman, MD Myla Goldman, MD Pedro Gonzalez-Alegre, MD Ari Green, MD Robert S. Greenwood, MD, FAAN David M. Greer, MD Rishi Gupta, MD Roop Gursahani, MD Amy K. Guzik, MD Katrina A. Gwinn, MD Karen Gylys, PhD, RN Atticus Hainsworth, MD E. Clarke Haley, Jr., MD, FAAN Rashmi B. Halker, MD Roy H. Hamilton, MD, MS John Hart, MD Anhar Hassan, MBBCH Michael K. Hehir, II, MD Victor W. Henderson, MD, FAAN David N. Herrmann, MD, FAAN Michio Hirano, MD, FAAN Timea M. Hodics, MD Yolanda Holler, MD Julia Holtmann, MD Muhammad Shazam Hussain, MD Matilde Inglese, MD, PhD Kurt A. Jaeckle, MD, FAAN Alan C. Jackson, MD, FAAN

2O14 Scientific Abstract Listing and Annual Meeting Information

Carlayne E. Jackson, MD, FAAN Michael S. Jaffee, MD, FAAN Nathalie Jette, MD, MSc, FRCPC Glen Jickling, MD Barbara C. Jobst, MD, FAAN Nicholas Elwood Johnson, MD S. Andrew Josephson, MD Tudor G. Jovin, MD Vern C. Juel, MD, FAAN Larry Junck, MD Andres M. Kanner, MD Orhun H. Kantarci, MD Jonathan S. Katz, MD Daniel Kaufer, MD, FAAN Claudia Kawas, MD Mark Keegan, MD Omar A. Khan, MD, PhD Babar Khokhar, MD Eric Klawiter, MD Peter J. Koehler, MD, PhD, FAAN Matthew A. Koenig, MD Martin Kohrmann, MD Mohamad Koubeissi, MD, FAAN Jeff Kraakevik, MD Fred A. Lado, MD Annette M. Langer-Gould, MD Maarten G. Lansberg, MD Douglas J. Lanska, MD, FAAN Suzette M. LaRoche, MD, FAAN Alan D. Legatt, MD, PhD, FAAN Richard A. Lewis, MD, FAAN David S. Liebeskind, MD, FAAN Arne Lindgren, MD Italo Linfante, MD Carol F. Lippa, MD Eric L. Logigian, MD, FAAN Zachary N. London, MD Jau-Shin Lou, MD, PhD, FAAN Fred D. Lublin, MD, FAAN Jennifer Lyons, MD Jennifer J. Majersik, MD Andrew Mammen, MD, PhD Ruth-Ann Marrie, MD Randolph S. Marshall, MD, FAAN Warren P. Mason, MD

Katherine D. Mathews, MD Farrah J. Mateen, MD Kimford J. Meador, MD, FAAN Matthew N. Meriggioli, MD, FAAN Tom Mikkelsen, MD Martha Morrell, MD, FAAN Ellen M. Mowry, MD Tahseen Mozaffar, MD, FAAN Susanne Muehlschlegel, MD Nils Hendrik Mueller, MD Louis Burt Nabors, III, MD Abraham J. Nagy, MD Sandra Narayanan, MD Avindra Nath, MBBS, FAAN Mohit Neema, MD Lawrence C. Newman, MD, FAAN David E. Newman-Toker, MD, PhD, FAAN Thanh Ngoc Nguyen, MD Paul Alan Nyquist, MD, MPH Darin T. Okuda, MD Adriana Elena Palade, MD Mamatha Pasnoor, MD Neepa J. Patel, MD Steven G. Pavlakis, MD, FAAN Aimee Lucinda Pierce, MD Istvan Pirko, MD, FAAN Sean J. Pittock, MD Ela B. Plow, PhD Ann N. Poncelet, MD Shyam Prabhakaran, MD J. Javier Provencio, MD, FAAN Vinaykumar Puduvalli, MD John Pula, MD Svetlana Pundik, MD Mark S. Quigg, MD Goran Rakocevic, MD Anthony Reder, MD Daniel Reich, MD,PhD Awais Riaz, MD, PhD, FAAN John Ringman, MD Ramon L. Rodriguez, MD Michael R. Rose, MD Yelena Roshchina, MD Natalia Sana Rost, MD, FAAN Janet C. Rucker, MD



Robert L. Ruff, MD, PhD, FAAN Seward B. Rutkove, MD Ned C. Sacktor, MD Joseph E. Safdieh, MD Juan R. Sanchez-Ramos, MD, PhD Valeria Sansone, MD Sean I. Savitz, MD Michael Joel Schneck, MD, FAAN Todd J. Schwedt, MD Lauren Seeberger, MD Benjamin M. Segal, MD Duygu Selcen, MD, FAAN Linda M. Selwa, MD, FAAN Kathleen M. Shannon, MD William R. Shapiro, MD, FAAN Kazim Ali Sheikh, MD Kevin N. Sheth, MD Holly A. Shill, MD Joshua M. Shulman, MD Nancy L. Sicotte, MD, FAAN Lisa C. Silbert, MD, FAAN David K. Simon, MD, PhD Joseph I. Sirven, MD, FAAN Jeffrey Statland, MD Israel Steiner, MD Victor W. Sung, MD Firas A. Taha, MD Nilufer Taner, MD, PhD Alrabi Tawil, MD, FAAN Edmond Teng, MD, PhD Claudia M. Testa, MD, PhD William H. Theodore, MD, FAAN Parthasarathy Thirumala, MD Matthew J. Thurtell, MD Michel T. Torbey, MD, MPH Helen Tremlett, PhD, BPharm Jay A. Van Gerpen, MD Panayiotis N. Varelas, MD, PhD Kathryn Rae Wagner, MD, PhD David Walk, MD Michael Mei-Hwa Wang, MD Michael F. Waters, MD, PhD Nathaniel F. Watson, MD Emmanuelle Waubant, MD, FAAN Thomas W. Weber, MD

Bianca Weinstock-Guttman, MD Patrick Y. Wen, MD, FAAN Norman S. Werdiger, MD, FAAN Dean M. Wingerchuk, MD, FAAN Elaine C. Wirrell, MD George F. Wittenberg, MD, PhD Bradford B. Worrall, MD, MSc, FAAN James P. Wymer, MD, PhD, FAAN Dileep R. Yavagal, MD Manuel S. Yepes, MD Scott S. Zamvil, MD, PhD, FAAN Wendy C. Ziai, MD Charles Zollinger, MD

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Meeting Information and Contacts Hotel Reservation Deadline:

March 26, 2014 Meeting Registration Deadline:

April 3, 2014 Registration, Hotel, and Travel Reservations:

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Annual Meeting Oversight

Science Program

Corporate Relations

Catherine M. Rydell, CAE Chief Executive Officer/Executive Director, AAN, AAN Institute, and American Brain Foundation

[email protected]

Alberta Zais Director, Corporate Relations

Christine E. Phelps Deputy Executive Director, AANI and American Brain Foundation

Erin Jackson Senior Manager, Scientific Programs Nate Kosher Senior Administrator, Scientific Programs Registration

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158

Laurie Dixon Administrator, Registration and Logistics

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Lucy Persaud Samaroo Manager, Education

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Affiliate Events

Practice and Advocacy Related Issues

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2O14 Scientific Abstract Listing and Annual Meeting Information

[email protected] Rod Larson Chief Health Policy Officer For direct email and phone contacts, please contact Member Services at: [email protected] (800) 879-1960 or International (612) 928-6000

Take Your Commitment to Your Profession to the Next Level 2O14 AAN Physician Leadership Programs Whether you want to be a mentor or an advocate, to guide or inspire others, you need to cultivate the skills to be an effective leader.

NEW for 2O14! Monday, April 28, 9:OO a.m.-5:OO p.m.

Women in Leadership The AAN is seeking talented, highly motivated AAN member women with a commitment to neurology who are interested in learning from successful female members in the field of neurology, including members of the AAN Board of Directors, about how to lead at senior levels. If this is you, apply today for the new Women in Leadership course during the 2014 AAN Annual Meeting in Philadelphia! Selected recipients will receive complimentary registration for this course. Directors:

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Apply now at AAN.com/view/WomenLead. Sunday, April 27, 8:OO a.m.-12:OO p.m.

Life Reimagined Are you at a point in your life where you are asking “What’s next?” You’ve finished one chapter and have not written the next. Many of us face these transitions at midlife, but they can happen at any point. It’s a time of enormous potential and it defines a whole new phase of life. It’s called a Life Reimagined. Director:

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2O14 Scientific Abstract Listing and Annual Meeting Information

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